PTCT PTC Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · Ver em SEC EDGAR ↗
$72,62
Preço · Ago 19, 2026
Fundamentais a partir de Jul 30, 2026

Sobre PTC Therapeutics, Inc. - Common Stock Visão geral da empresa da Wikipedia

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

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PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

In September 2009, PTC entered into an agreement with Roche for the development of orally bioavailable small molecules for central nervous system diseases. PTC acquired the Bio-e platform in 2019.

Products

In 2017, PTC acquired Emflaza (deflazacort) from Marathon Pharmaceuticals. PTC also owns Translarna, (Ataluren) marketed for nonsense mutation Duchenne muscular dystrophy. Together, the two products generated revenues of 174 million dollars and 260 million dollars in 2017 and 2018 respectively.

PTC has the commercialization rights for WAYLIVRA (volanesorsen) in Latin America.

In 2018, PTC acquired Agilis Biotherapeutics and a gene therapy candidate, GT-AADC, with its compelling clinical data in treating aromatic L-amino acid decarboxylase (AADC) deficiency. AADC deficiency is a rare CNS disorder arising from reductions in the enzyme AADC that result from mutations in the dopa decarboxylase (DDC) gene. As of 2024, the AAV based treatment for AADC deficiency has been approved by the FDA and commercialized in the United States as Kebilidi. It is the first FDA-approved gene therapy treatment for AADC deficiency. This same product was granted EMA approval for use in the European Union under the name Upstaza.

Pipeline

In 2020, PTC acquired Censa Pharmaceuticals, Inc., a biopharmaceutical company focused on the development of CNSA-001 (sepiapterin), a clinical-stage investigational therapy for orphan metabolic diseases, including phenylketonuria (PKU) and other diseases associated with defects in the tetrahydrobiopterin (BH4) biochemical pathways diagnosed at birth.

In 2020, PTC announced the FDA approval of Evrysdi (risdiplam) for the treatment of spinal muscular atrophy (SMA) in adults and children 2 months and older.

In 2024, Novartis has committed $1 billion upfront in a licensing deal with PTC Therapeutics for an experimental treatment for Huntington’s disease, with the potential for an additional $1.9 billion tied to achieving specific development, regulatory, and commercial milestones. PTC Therapeutics’ therapy, known as PTC518, is an oral medication designed to reduce the production of the mutant protein linked to the genetic mutation responsible for the disease. This mutant protein is believed to contribute to neuronal death, driving disease progression. In June, interim data from a Phase 2 trial indicated that PTC518 successfully lowered levels of the mutant protein in both blood and cerebrospinal fluid.

Fonte: Wikipedia (Inglês), CC BY-SA 4.0 · Ver na Wikipedia ↗

Wikidata ↗

PTCT Instantâneo da Ação Preço, capitalização de mercado, P/E, EPS, ROE, dívida/patrimônio, intervalo de 52 semanas

Preço
$72.62
Capitalização de Mercado
$5.92B
P/E (TTM)
9.3
EPS (TTM)
$7.78
Receita (TTM)
$1.73B
Rendimento div.
ROE
-331.5%
Dívida/Capital
-1.4
Intervalo 52 Semanas
$48 – $91

PTCT Gráfico de Preço da Ação OHLCV diário com indicadores técnicos — panorâmica, zoom e personalize sua visualização

Desempenho de 10 Anos Tendências de receita, lucro líquido, margens e EPS

Receita e Lucro Líquido $1.73B
10-point trend, +1992.6%
2016-12-31 2025-12-31
EPS $7.78
7-point trend, +282.2%
2019-12-31 2025-12-31
Fluxo de caixa livre $702M
9-point trend, +766.7%
2016-12-31 2025-12-31
Margens 39.4%

Avaliação Rácios P/E, P/S, P/B, EV/EBITDA — a ação está cara ou barata?

Métrica
Tendência de 5 anos
PTCT
Mediana de Pares
P/E (TTM)
5-point trend, +282.1%
9.3
37.2
P/S (TTM)
5-point trend, -68.0%
3.4
9.9
P/B
5-point trend, -441.5%
-28.8
8.3
EV / EBITDA
5-point trend, +156.1%
4.7
Price / FCF (Preço / FCF)
5-point trend, +143.9%
8.4

Lucratividade Margens bruta, operacional e líquida; ROE, ROA, ROIC

Métrica
Tendência de 5 anos
PTCT
Mediana de Pares
Operating Margin (Margem Operacional)
5-point trend, +144.2%
50.1%
Net Profit Margin (Margem de Lucro Líquido)
5-point trend, +134.3%
39.4%
-15.1%
ROA
5-point trend, +229.7%
29.7%
-23.3%
ROE
5-point trend, -275.6%
-331.5%
-30.6%
ROIC
5-point trend, +1860.3%
1044.7%

Saúde financeira Dívida, liquidez, solvência — força do balanço patrimonial

Métrica
Tendência de 5 anos
PTCT
Mediana de Pares
Debt / Equity (Dívida / Patrimônio Líquido)
5-point trend, -317.7%
-1.4
Current Ratio (Índice de liquidez corrente)
5-point trend, -47.1%
2.3
6.3
Quick Ratio (Índice de Liquidez Seca)
5-point trend, -48.1%
2.2

Crescimento Crescimento da receita, EPS e lucro líquido: YoY, CAGR 3 anos, CAGR 5 anos

Métrica
Tendência de 5 anos
PTCT
Mediana de Pares
Revenue YoY (Receita Ano a Ano)
5-point trend, +221.3%
114.5%
Revenue CAGR 3Y (CAGR Receita 3A)
5-point trend, +221.3%
35.3%
Revenue CAGR 5Y (CAGR Receita 5A)
5-point trend, +221.3%
35.4%

Métricas por Ação EPS, valor patrimonial por ação, fluxo de caixa por ação, dividendo por ação

Métrica
Tendência de 5 anos
PTCT
Mediana de Pares
EPS (Diluted) (EPS (Diluído))
5-point trend, +204.7%
$7.78

Eficiência de Capital Giro de ativos, giro de estoques, giro de contas a receber

Métrica
Tendência de 5 anos
PTCT
Mediana de Pares

PTCT Consenso dos analistas Opiniões de analistas otimistas e pessimistas, preço-alvo de 12 meses, potencial de alta

COMPRA 21 analistas
  • Compra forte 6 28,6%
  • Compra 11 52,4%
  • Manter 3 14,3%
  • Venda 1 4,8%
  • Venda forte 0 0,0%

Preço-alvo de 12 meses

14 analistas · 2026-08-13
Alvo mediano $98.00 +34,9%
Alvo médio $97.86 +34,8%

Histórico de Lucros EPS real vs. estimativa, surpresa %, taxa de acerto, próxima data de resultados

Surpresa Média
1.9%
Período EPS Actual EPS est. Surpresa
30 de Junho de 2026 $0.92 $0.43 0.49%
31 de Março de 2026 $-0.03 $-0.48 0.45%
31 de Dezembro de 2025 $-1.67 $0.04 -1.7%
30 de Setembro de 2025 $0.20 $-1.40 1.6%
30 de Junho de 2025 $-0.83 $-1.08 0.25%
31 de Março de 2025 $10.04 $-0.22 10.3%

Comparação de pares (subindústria GICS) Métricas chave vs pares do setor

Ticker Capitalização de Mercado P/E Receita YoY Margem Líquida ROE Margem Bruta
PTCT $6.19B 9.8 114.5% 39.4% -331.5%
MIRM $4.10B -168.1 54.7% -4.5% -8.2%
COGT $5.72B -16.4 -83.1%
DNTH $1.78B -9.8 -67.3% -7973.3% -40.8%
ERAS $1.06B -8.5 -35.7%
CAI $7.62B -8.4 97.0% -8.4% -13.2%
TVTX $3.47B -131.8 110.5% -5.2% -34.6%
ACAD $4.55B 11.6 11.9% 36.5% 38.1%
DYN $3.23B -5.6 -57.8%
PBLS
CELC $4.81B -26.3 -244.3%

Fundamentos Completos Todas as métricas por ano — demonstração de resultados, balanço patrimonial, fluxo de caixa

Demonstração de Resultados 15
Dados anuais de Demonstração de Resultados para PTCT
Métrica Tendência 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +6755.4% $1.73B $807M $938M $699M $539M $381M $307M $265M $194M $83M $37M $25M
Cost of Revenue 5-point trend, +12135000.00 · · · · · · $12M $13M $5M $0 $0 ·
R&D Expense 12-point trend, +470.2% $455M $534M $667M $651M $541M $478M $257M $172M $117M $118M $122M $80M
SG&A Expense 12-point trend, +674.5% $347M $301M $333M $326M $286M $245M $203M $154M $121M $97M $82M $45M
Operating Expenses 12-point trend, +592.9% $864M $1.11B $1.38B $1.15B $913M $813M $548M $380M $259M $215M $204M $125M
Operating Income 12-point trend, +972.1% $867M $-303M $-440M $-447M $-374M $-432M $-241M $-116M $-64M $-132M $-167M $-99M
Other Non-op 12-point trend, -8391.1% $-18M $7M $10M $-49M $-58M $85M $14M $129.0K $-1M $-1M $-465.0K $-213.0K
Pretax Income 12-point trend, +807.6% $697M $-363M $-696M $-587M $-518M $-403M $-240M $-128M $-78M $-142M $-170M $-98M
Income Tax 12-point trend, +397.8% $14M $176.0K $-70M $-28M $6M $35M $12M $-29.0K $1M $569.0K $485.0K $-5M
Net Income 12-point trend, +828.1% $683M $-363M $-627M $-559M $-524M $-438M $-252M $-128M $-79M $-142M $-170M $-94M
EPS (Basic) 10-point trend, +388.9% $8.58 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 $-2.75 $-2.02 · · $-2.97
EPS (Diluted) 8-point trend, +362.0% $7.78 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 · · · · $-2.97
Shares (Basic) 8-point trend, +152.0% 79,534,290 76,845,055 74,838,292 71,728,634 70,466,393 66,027,908 58,863,185 · · · · 31,565,310
Shares (Diluted) 8-point trend, +179.8% 88,311,494 76,845,055 74,838,292 71,728,634 70,466,393 66,027,908 58,863,185 · · · · 31,565,310
EBITDA 11-point trend, +1011.1% $906M $-227M $-203M · $-310M $-388M $-209M $-90M $-47M $-132M $-167M $-99M
Balanço Patrimonial 27
Dados anuais de Balanço Patrimonial para PTCT
Métrica Tendência 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +1879.3% $985M $780M $594M $280M $190M $209M $288M $169M $112M $58M $58M $50M
Short-term Investments 12-point trend, +261.9% $961M $360M $283M $131M $584M $895M $399M $58M $79M $173M $281M $265M
Receivables 12-point trend, +3986.0% $182M $159M $161M $156M $110M $70M $56M $68M $40M $25M $11M $4M
Inventory 10-point trend, +79647000.00 $80M $23M $31M $22M $16M $19M $19M $16M $11M $0 · ·
Prepaid Expense 12-point trend, +1632.5% $67M $44M $150M $106M $55M $39M $18M $9M $7M $5M $6M $4M
Current Assets 12-point trend, +602.8% $2.27B $1.37B $1.22B $694M $954M $1.23B $779M $321M $249M $261M $356M $324M
PP&E (Net) 12-point trend, +504.6% $55M $61M $87M $73M $53M $34M $22M $13M $8M $7M $9M $9M
PP&E (Gross) 12-point trend, +200.4% $102M $94M $138M $110M $80M $52M $33M $20M $41M $38M $37M $34M
Accum. Depreciation 12-point trend, +88.6% $47M $33M $51M $37M $27M $18M $12M $7M $33M $31M $28M $25M
Goodwill 9-point trend, +82341000.00 $82M $82M $82M $82M $82M $82M $82M $82M $0 · · ·
Intangibles 10-point trend, +388753000.00 $389M $119M $379M $706M $725M $715M $710M $701M $133M $0 · ·
Total Assets 12-point trend, +769.9% $2.90B $1.71B $1.90B $1.71B $1.94B $2.21B $1.62B $1.12B $392M $269M $365M $333M
Accounts Payable 12-point trend, +1001.9% $45M $17M $6M $27M $23M $19M $10M $6M $15M $6M $6M $4M
Current Liabilities 12-point trend, +2882.1% $968M $581M $603M $406M $509M $277M $236M $167M $82M $50M $45M $32M
Capital Leases 7-point trend, +937.7% $94M $75M $98M $101M $74M $79M $9M · · · · ·
Deferred Tax 7-point trend, +55905000.00 · · $56M $103M $137M $137M $131M $122M $0 · · ·
Other Non-current Liabilities 11-point trend, +501.8% $14M $21M $141.0K $3M · $1M $141.0K $58.0K $243.0K $335.0K $2M $2M
Total Liabilities 12-point trend, +8832.1% $3.10B $2.80B $2.71B $2.05B $1.94B $1.73B $1.03B $768M $235M $150M $139M $35M
Long-term Debt 4-point trend, +197.6% · · · · $431M · $314M $153M $145M · · ·
Total Debt 10-point trend, +203.0% $287M $285M $284M · $431M $309M $314M $153M $145M $98M $95M ·
Common Stock 12-point trend, +142.4% $80.0K $77.0K $75.0K $72.0K $71.0K $70.0K $62.0K $51.0K $42.0K $34.0K $34.0K $33.0K
Paid-in Capital 12-point trend, +280.8% $2.75B $2.57B $2.47B $2.31B $2.12B $2.17B $1.80B $1.29B $967M $856M $820M $722M
Retained Earnings 12-point trend, -601.5% $-2.96B $-3.65B $-3.28B $-2.66B $-2.10B $-1.63B $-1.19B $-939M $-814M $-735M $-593M $-423M
AOCI 12-point trend, +1524.8% $11M $-26M $-1M $5M $-24M $-61M $-11M $1M $4M $-1M $-1M $-737.0K
Stockholders' Equity 12-point trend, -168.8% $-205M $-1.10B $-819M $-347M $1M $482M $594M $351M $156M $120M $226M $298M
Liabilities + Equity 12-point trend, +769.9% $2.90B $1.71B $1.90B $1.71B $1.94B $2.21B $1.62B $1.12B $392M $269M $365M $333M
Shares Outstanding 12-point trend, +147.7% 81,474,366 77,704,188 75,708,889 73,104,692 70,828,226 69,718,096 61,935,870 50,606,147 41,612,395 34,169,410 33,916,559 32,898,392
Fluxo de Caixa 16
Dados anuais de Fluxo de Caixa para PTCT
Métrica Tendência 202520242023202220212020201920182017201620152014
D&A 11-point trend, +1249.6% $39M $76M $237M $129M $64M $43M $32M $26M $18M $3M $3M ·
Stock-based Comp 12-point trend, +286.1% $75M $75M $102M $110M $104M $70M $42M $33M $31M $35M $34M $19M
Deferred Tax 12-point trend, -3000.00 $-3.0K $-56M $-47M $-34M $377.0K $6M $9M $0 $199.0K $-199.0K $0 $0
Amort. of Intangibles 11-point trend, +24742000.00 $25M $61M $223M $117M $55M $37M $28M $23M $15M $0 $0 ·
Restructuring · · · · · · · · $0 · · ·
Other Non-cash 8-point trend, -513.8% $-85M $161M $177M · $105M $124M $70M $41M $20M · · ·
Operating Cash Flow 12-point trend, +1341.7% $711M $-108M $-158M $-357M $-251M $-194M $-99M $-28M $-10M $-104M $-124M $-57M
CapEx 12-point trend, +90.0% $9M $7M $28M $32M $28M $18M $14M $7M $3M $2M $3M $5M
Investing Cash Flow 12-point trend, -493.8% $-862M $44M $-177M $290M $219M $-562M $-387M $-43M $13M $104M $-21M $-145M
Net Debt Issued 2-point trend, +100.0% · · · · · · · · · $0 · $-49.0K
Stock Issued 7-point trend, -88.1% · · · · · $28M $324M $118M $0 $0 $0 $236M
Net Stock Activity 5-point trend, -88.1% · · · · · $28M $324M $118M · $0 · $236M
Financing Cash Flow 12-point trend, +39.6% $331M $256M $646M $168M $21M $669M $613M $132M $44M $968.0K $154M $237M
Net Change in Cash 12-point trend, +491.3% $203M $185M $314M $99M $-19M $-79M $126M $58M $53M $299.0K $8M $34M
Taxes Paid 12-point trend, +36854000.00 $37M $18M $14M $5M $8M $26M $2M $2M $1M $943.0K $111.0K $0
Free Cash Flow 11-point trend, +1233.9% $702M $-114M $-187M · $-280M $-212M $-112M $-35M $-13M $-105M $-127M $-62M
Lucratividade 7
Dados anuais de Lucratividade para PTCT
Métrica Tendência 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, +112.7% 50.1% -37.5% -46.9% · -69.5% -113.4% -78.6% -43.7% -33.1% -159.7% -454.6% -393.8%
Net Margin 11-point trend, +110.6% 39.4% -45.0% -66.8% · -97.3% -115.1% -82.0% -48.4% -40.6% -171.8% -463.6% -371.4%
Pretax Margin 11-point trend, +110.3% 40.2% -45.0% -74.2% · -96.2% -105.8% -78.2% -48.4% -40.0% -171.1% -462.3% -390.0%
EBITDA Margin 11-point trend, +113.3% 52.3% -28.1% -21.6% · -57.6% -102.0% -68.1% -33.8% -24.0% -159.7% -454.6% -393.8%
ROA 11-point trend, +176.7% 29.7% -20.2% -34.8% · -25.3% -22.9% -18.3% -17.0% -23.9% -44.8% -48.6% -38.6%
ROE 11-point trend, -669.1% -331.5% 33.8% 84.1% · -985.1% -88.3% -40.0% -34.8% -57.2% -82.2% -65.0% -43.1%
ROIC 11-point trend, +3393.6% 1044.7% 37.2% 74.0% · -87.4% -59.4% -27.8% -23.0% -21.7% -60.9% -52.3% -31.7%
Liquidez e Solvência 4
Dados anuais de Liquidez e Solvência para PTCT
Métrica Tendência 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -76.4% 2.3 2.4 2.0 · 1.9 4.4 3.3 1.9 3.0 5.3 7.8 10.0
Quick Ratio 11-point trend, -77.7% 2.2 2.2 1.7 · 1.7 4.2 3.1 1.8 2.8 5.2 7.7 9.8
Debt / Equity 10-point trend, -433.5% -1.4 -0.3 -0.3 · 300.0 0.6 0.5 0.4 0.9 0.8 0.4 ·
LT Debt / Equity 9-point trend, -162.1% · -0.3 -0.3 · 196.0 0.6 0.5 0.4 0.9 0.8 0.4 ·
Eficiência 3
Dados anuais de Eficiência para PTCT
Métrica Tendência 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, +622.2% 0.8 0.4 0.5 · 0.3 0.2 0.2 0.4 0.6 0.3 0.1 0.1
Inventory Turnover 2-point trend, -19.5% · · · · · · 0.7 · 0.9 · · ·
Receivables Turnover 11-point trend, +8.9% 10.2 5.1 5.9 · 6.0 6.1 5.0 4.9 6.0 4.6 4.7 9.3
Por Ação 5
Dados anuais de Por Ação para PTCT
Métrica Tendência 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, -127.8% $-2.52 $-14.13 $-10.81 · $0.02 $6.91 $9.60 $6.93 $3.76 $3.50 $6.66 $9.07
Revenue / Share 5-point trend, +2350.3% $19.60 $10.50 $12.53 · $7.64 · · · · · · $0.80
Cash Flow / Share 5-point trend, +543.8% $8.05 $-1.40 $-2.12 · $-3.57 · · · · · · $-1.81
Cash / Share 11-point trend, +699.2% $12.09 $10.03 $7.85 · $2.68 $3.00 $4.65 $3.35 $2.69 $1.71 $1.71 $1.51
EPS (TTM) 12-point trend, +362.0% $7.78 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 $-3.21 $-3.21 $-3.21 $-3.21 $-2.97
Taxas de Crescimento 3
Dados anuais de Taxas de Crescimento para PTCT
Métrica Tendência 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +176.3% 114.5% -14.0% 34.2% 29.8% 41.4% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +0.7% 35.3% 14.4% 35.0% · · · · · · · · ·
Revenue CAGR 5Y 35.4% · · · · · · · · · · ·
Avaliação (TTM) 13
Dados anuais de Avaliação (TTM) para PTCT
Métrica Tendência 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +6755.4% $1.73B $807M $938M $699M $539M $381M $307M $265M $194M $83M $37M $25M
Net Income TTM 12-point trend, +828.1% $683M $-363M $-627M $-559M $-524M $-438M $-252M $-128M $-79M $-142M $-170M $-94M
Market Cap 11-point trend, +263.4% $6.19B $3.51B $2.09B · $2.82B $4.25B $2.97B $1.74B $694M $373M $1.10B $1.70B
Enterprise Value 10-point trend, +430.1% $4.53B $2.65B $1.49B · $2.48B $3.46B $2.60B $1.66B $648M $239M $855M ·
P/E 12-point trend, +156.0% 9.8 -9.5 -3.3 -4.9 -5.4 -9.2 -11.2 -10.7 -5.2 -3.4 -10.1 -17.4
P/S 11-point trend, -94.7% 3.6 4.3 2.2 · 5.2 11.2 9.7 6.6 3.6 4.5 29.9 67.5
P/B 11-point trend, -628.2% -30.1 -3.2 -2.5 · 1961.8 8.8 5.0 5.0 4.4 3.1 4.9 5.7
P / Cash Flow 11-point trend, +129.3% 8.7 -32.6 -13.2 · -11.2 -21.9 -30.2 -62.8 -69.0 -3.6 -8.8 -29.7
P / FCF 11-point trend, +132.0% 8.8 -30.7 -11.2 · -10.1 -20.1 -26.5 -50.0 -52.7 -3.5 -8.6 -27.5
EV / EBITDA 10-point trend, +197.8% 5.0 -11.7 -7.4 · -8.0 -8.9 -12.5 -18.6 -13.9 -1.8 -5.1 ·
EV / FCF 10-point trend, +195.9% 6.5 -23.2 -8.0 · -8.9 -16.3 -23.2 -47.9 -49.2 -2.3 -6.7 ·
EV / Revenue 10-point trend, -88.7% 2.6 3.3 1.6 · 4.6 9.1 8.5 6.3 3.3 2.9 23.2 ·
Earnings Yield 12-point trend, +278.4% 10.2% -10.5% -30.4% -20.4% -18.6% -10.9% -8.9% -9.3% -19.2% -29.4% -9.9% -5.7%

Demonstrações Financeiras Demonstração de resultados, balanço patrimonial, fluxo de caixa — anual, últimos 5 anos

Demonstração de Resultados
2025-12-312024-12-312023-12-312022-12-312021-12-31
Receita $1.73B$807M$938M$699M$539M
Margem Operacional % 50.1%-37.5%-46.9%-69.5%
Lucro líquido $683M$-363M$-627M$-559M$-524M
EPS Diluído $7.78$-4.73$-8.37$-7.79$-7.43
Balanço Patrimonial
2025-12-312024-12-312023-12-312022-12-312021-12-31
Dívida / Patrimônio Líquido -1.4-0.3-0.3300.0
Índice de liquidez corrente 2.32.42.01.9
Índice de Liquidez Seca 2.22.21.71.7
Fluxo de Caixa
2025-12-312024-12-312023-12-312022-12-312021-12-31
Fluxo de caixa livre $702M$-114M$-187M$-280M

Sinais de trading Sinais recentes de compra/venda com preço de entrada e relação risco/recompensa

Minhas Métricas Sua lista pessoal — linhas selecionadas de Fundamentos Completos

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Investidores institucionais (13F) 404 declarantes · $5.4B total · Em 30 de Junho de 2026

Instituições que relatam a posse desta ação em seu Formulário 13F trimestral da SEC. Apenas posições compradas; um único declarante pode aparecer duas vezes para opções separadas. Grandes posições de compra/venda compensatórias geralmente refletem market-making ou inventário protegido, não convicção direcional.

Atividade institucional — Q2 2026 vs trimestre anterior
Novas posições Posições encerradas Aumentou Diminuído Variação líquida de ações
83 (+22 vs trimestre anterior) 43 (-9 vs trimestre anterior) 133 (-4 vs trimestre anterior) 109 (+6 vs trimestre anterior) +2.1M

Comparado a Q1 2026. Os registros do Formulário 13F da SEC devem ser feitos em até 45 dias após o final do trimestre, mais um pequeno período de tolerância para registrantes atrasados — trimestres ainda dentro desse período são ignorados em favor do par mais recente totalmente reportado.

Instituição Valor Ações % de 13F rastreado Tipo
RTW INVESTMENTS, LP $631.875.072 7.746.415 11,70% Ações
JANUS HENDERSON GROUP PLC $479.178.655 7.034.622 8,87% Ações
VANGUARD PORTFOLIO MANAGEMENT LLC $401.986.014 4.928.111 7,45% Ações
STATE STREET CORP $375.136.515 4.598.952 6,95% Ações
VANGUARD CAPITAL MANAGEMENT LLC $305.000.589 3.739.127 5,65% Ações
WELLINGTON MANAGEMENT GROUP LLP $292.435.873 3.585.091 5,42% Ações
WESTFIELD CAPITAL MANAGEMENT CO LP $159.563.645 1.956.156 2,96% Ações
GEODE CAPITAL MANAGEMENT, LLC $155.132.041 1.901.417 2,87% Ações
Hood River Capital Management LLC $141.818.662 1.738.613 2,63% Ações
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC $140.519.660 1.722.688 2,60% Ações
TANG CAPITAL MANAGEMENT LLC $122.355.000 1.500.000 2,27% Ações
Driehaus Capital Management LLC $117.469.528 1.440.107 2,18% Ações
Jefferies Financial Group Inc. $110.693.916 1.357.042 2,05% Ações
FULLER & THALER ASSET MANAGEMENT, INC. $94.361.749 1.156.819 1,75% Ações
Pictet Asset Management Holding SA $93.629.635 1.147.844 1,73% Ações
ARMISTICE CAPITAL, LLC $87.393.690 1.071.395 1,62% Ações
Blue Sparrow, LLC /DE $85.705.599 1.050.700 1,59% Ações
D. E. Shaw & Co., Inc. $77.478.857 949.845 1,43% Ações
Palo Alto Investors LP $74.950.268 918.846 1,39% Ações
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $64.449.436 790.112 1,19% Ações
RENAISSANCE TECHNOLOGIES LLC $59.015.895 723.500 1,09% Ações
Boston Partners $57.080.953 699.871 1,06% Ações
FMR LLC $56.956.987 698.259 1,05% Ações
BANK OF AMERICA CORP /DE/ $56.350.840 690.828 1,04% Ações
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $53.377.940 654.382 0,99% Ações
DIMENSIONAL FUND ADVISORS LP $51.486.821 631.199 0,95% Ações
VANGUARD FIDUCIARY TRUST CO $47.953.943 587.887 0,89% Ações
Ensign Peak Advisors, Inc $41.442.128 508.056 0,77% Ações
AMERICAN CENTURY COMPANIES INC $40.866.277 500.995 0,76% Ações
MANUFACTURERS LIFE INSURANCE COMPANY, THE $36.050.432 441.957 0,67% Ações
Parkman Healthcare Partners LLC $35.539.315 435.691 0,66% Ações
LOOMIS SAYLES & CO L P $35.387.921 433.835 0,66% Ações
Defilade Capital Management, L.P. $35.376.827 433.699 0,66% Ações
GOLDMAN SACHS GROUP INC $34.153.522 418.702 0,63% Ações
SUSQUEHANNA INTERNATIONAL GROUP, LLP $32.274.149 395.662 0,60% Ações
BNP PARIBAS FINANCIAL MARKETS $30.892.190 378.720 0,57% Ações
Qube Research & Technologies Ltd $25.398.777 311.374 0,47% Ações
ARMISTICE CAPITAL, LLC $24.471.000 300.000 0,45% Opção de compra
Public Sector Pension Investment Board $23.249.326 285.023 0,43% Ações
SEGALL BRYANT & HAMILL, LLC $22.165.424 271.735 0,41% Ações
CITADEL ADVISORS LLC $20.338.011 249.332 0,38% Ações
MORGAN STANLEY $18.990.210 232.808 0,35% Ações
Boxer Capital Management, LLC $16.314.000 200.000 0,30% Ações
RHUMBLINE ADVISERS $15.718.994 192.706 0,29% Ações
AMERIPRISE FINANCIAL INC $13.904.178 170.457 0,26% Ações
PRUDENTIAL FINANCIAL INC $13.746.176 168.520 0,25% Ações
BlackRock, Inc. $13.589.562 166.600 0,25% Ações
Rock Springs Capital Management LP $13.238.648 162.298 0,25% Ações
Hudson Bay Capital Management LP $13.033.091 159.778 0,24% Ações
Russell Investments Group, Ltd. $12.687.724 155.544 0,23% Ações
Schonfeld Strategic Advisors LLC $12.025.457 147.425 0,22% Ações
MARSHALL WACE, LLP $11.724.301 143.733 0,22% Ações
Swiss National Bank $11.539.300 141.465 0,21% Ações
Universal- Beteiligungs- und Servicegesellschaft mbH $11.063.583 135.633 0,20% Ações
Legal & General Group Plc $10.362.979 127.044 0,19% Ações
CITIGROUP INC $9.272.143 113.671 0,17% Ações
FIRST TRUST ADVISORS LP $9.246.285 113.354 0,17% Ações
Longaeva Partners L.P. $9.119.771 111.803 0,17% Ações
JUPITER ASSET MANAGEMENT LTD $8.927.184 109.442 0,17% Ações
SCHRODER INVESTMENT MANAGEMENT GROUP $8.215.404 100.716 0,15% Ações
SECTOR GAMMA AS $8.157.000 100.000 0,15% Ações
WCM INVESTMENT MANAGEMENT, LLC $7.651.184 93.799 0,14% Ações
PANAGORA ASSET MANAGEMENT INC $7.256.141 88.956 0,13% Ações
VOYA INVESTMENT MANAGEMENT LLC $7.239.501 88.752 0,13% Ações
ALLIANCEBERNSTEIN L.P. $7.217.488 105.937 0,13% Ações
Aquatic Capital Management LLC $6.808.648 83.470 0,13% Ações
XTX Topco Ltd $6.682.459 81.923 0,12% Ações
MOORE CAPITAL MANAGEMENT, LP $6.165.713 75.588 0,11% Ações
PINNACLE ASSOCIATES LTD $5.745.383 70.435 0,11% Ações
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $5.744.722 84.320 0,11% Ações
VANGUARD ASSET MANAGEMENT, Ltd $5.614.300 68.828 0,10% Ações
Capricorn Fund Managers Ltd $5.212.323 63.900 0,10% Ações
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5.000.241 61.300 0,09% Opção de compra
INTECH INVESTMENT MANAGEMENT LLC $4.696.882 57.581 0,09% Ações
ExodusPoint Capital Management, LP $4.672.166 57.278 0,09% Ações
LOS ANGELES CAPITAL MANAGEMENT LLC $4.561.884 55.926 0,08% Ações
BARCLAYS PLC $4.169.858 51.120 0,08% Ações
ORBIMED ADVISORS LLC $4.005.087 49.100 0,07% Ações
MetLife Investment Management, LLC $3.932.653 48.212 0,07% Ações
Point72 Europe (London) LLP $3.829.919 62.407 0,07% Ações
MILLENNIUM MANAGEMENT LLC $3.792.516 46.494 0,07% Ações
Phocas Financial Corp. $3.766.087 46.170 0,07% Ações
MARTINGALE ASSET MANAGEMENT L P $3.627.826 44.475 0,07% Ações
Quadrature Capital Ltd $3.589.488 44.005 0,07% Ações
SUSQUEHANNA INTERNATIONAL GROUP, LLP $3.531.981 43.300 0,07% Opção de venda
STATE OF WISCONSIN INVESTMENT BOARD $3.436.299 42.127 0,06% Ações
CREDIT AGRICOLE S A $3.344.370 41.000 0,06% Ações
Fisher Asset Management, LLC $3.322.345 40.730 0,06% Ações
HSBC HOLDINGS PLC $3.200.425 38.732 0,06% Ações
NEW YORK STATE COMMON RETIREMENT FUND $3.134.490 38.427 0,06% Ações
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $3.114.179 38.178 0,06% Ações
CenterBook Partners LP $3.082.938 37.795 0,06% Ações
Rafferty Asset Management, LLC $3.069.805 37.634 0,06% Ações
FIFTH THIRD BANCORP $3.044.843 37.328 0,06% Ações
BURNEY CO/ $3.044.192 37.320 0,06% Ações
Vanguard Global Advisers, LLC $3.033.180 37.185 0,06% Ações
Arrowpoint Investment Partners (Singapore) Pte. Ltd. $3.007.731 36.873 0,06% Ações
Louisiana State Employees Retirement System $2.969.148 36.400 0,05% Ações
JANE STREET GROUP, LLC $2.854.950 35.000 0,05% Opção de venda
CASTLEARK MANAGEMENT LLC $2.765.223 33.900 0,05% Ações

Executivos da empresa 33 insiders · 13 diretores · 14 conselheiros

Investidor com informação privilegiada Função Última atividade Ações detidas Compras 12m Vendas 12m Líquido 12m
Stuart Walter Peltz Chief Executive Officer 1 de Fevereiro de 2022 S 38.728 0 0 $0
Pierre Gravier CHIEF FINANCIAL OFFICER 14 de Julho de 2026 S 83.986 0 1 $-280.743
Emily Luisa Hill Chief Financial Officer 1 de Fevereiro de 2022 S 37.169 0 0 $0
Shane William Charles Kovacs Chief Financial Officer 9 de Maio de 2017 M 37.850 0 0 $0
Claudia De Oliveira Ribeiro Hirawat President 15 de Janeiro de 2015 M 39.247 0 0 $0
Marcio Souza Chief Operating Officer 10 de Fevereiro de 2020 M 6.744 0 0 $0
Neil Gregory Almstead CHIEF TECHNICAL OPS OFFICER 9 de Julho de 2026 M 60.299 0 20 $-9.184.852
Mark Elliott Boulding EXEC. VP AND CLO 6 de Julho de 2026 M 105.272 0 12 $-1.254.986
Christine Marie Utter SVP, CHIEF ACCOUNTING OFFICER 17 de Junho de 2026 M 70.199 0 1 $-1.487.474
Eric Pauwels CHIEF BUSINESS OFFICER 10 de Junho de 2026 S 73.411 0 28 $-7.477.160
Mark Rothera Chief Commercial Officer 24 de Maio de 2017 M 33.739 0 0 $0
Tuyen Ong Chief Medical Officer 3 de Janeiro de 2017 A 6.000 0 0 $0
Robert J. Spiegel Chief Medical Officer 4 de Janeiro de 2016 A 3.239 0 0 $0
Hege Elisabeth Sollie-Zetlmayer Conselheiro 28 de Julho de 2026 A 52.526 0 0 $0
Mary L. Smith Conselheiro 9 de Julho de 2026 M 21.813 0 2 $-1.425.060
Stephanie Okey Conselheiro 7 de Janeiro de 2022 A 4.163 0 0 $0
Emma Reeve Conselheiro 7 de Janeiro de 2022 A 7.528 0 0 $0
Allan Steven Jacobson Conselheiro 7 de Janeiro de 2022 A 8.348 0 0 $0
Dawn Svoronos Conselheiro 7 de Janeiro de 2022 A 29.755 0 0 $0
Jerome B Zeldis Conselheiro 7 de Janeiro de 2022 A 6.500 0 0 $0
Cameron Geoffrey Mcdonough Conselheiro 3 de Janeiro de 2017 A 0 0 $0
Adam Koppel Conselheiro 3 de Janeiro de 2017 A 2.333.333 0 0 $0
Ronald C Renaud JR Conselheiro 3 de Janeiro de 2017 A 0 0 $0
Richard Aldrich Conselheiro 8 de Junho de 2015 M 0 0 0 $0
Michael L Kranda Conselheiro 16 de Março de 2015 S 2.242 0 0 $0
Axel Bolte Conselheiro 25 de Junho de 2013 P 20.000 0 0 $0
HBM Healthcare Investments (Cayman) Ltd. Detentor de 10% 17 de Dezembro de 2013 S 2.441.504 0 0 $0
Matthew B. Klein 4 de Agosto de 2026 S 383.868 0 1 $-705.722
Michael Schmertzler 2 de Janeiro de 2026 A 163.266 0 0 $0
Glenn Steele JR MD PHD 2 de Janeiro de 2026 A 22.500 0 1 $-916.200
David P Southwell 2 de Janeiro de 2026 A 20.850 0 0 $0
Complete Pharma Holdings II, LLC 28 de Abril de 2017 J 0 0 0 $0
CREDIT SUISSE/ 25 de Junho de 2013 C 2.256.882 0 0 $0

Executivos de declarações SEC Formulário 3/4/5; líquido = apenas P/V de mercado aberto

Ativistas e proprietários de 5%+ 3 participações

Investidores que apresentaram o Schedule 13D da SEC — propriedade benéfica acima de 5% com a intenção de influenciar o emissor (participações ativistas, campanhas no conselho, M&A). Cada linha mostra o estado mais recente conhecido da posição desse declarante.

Declarante Declarado Participação Status Propósito Declaração
Brookside Capital Partners Fund, L.P., Brookside Capital Trading Fund, L.P. ×5 declarações 30 de Janeiro de 2015 Declaração inicial SEC
HBM Healthcare Investments (Cayman) Ltd. (“HBM”) ×2 declarações 12 de Novembro de 2014 Declaração inicial SEC
HBM Healthcare Investments (Cayman) Ltd. 5 de Julho de 2013 Declaração inicial SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Participação em ETFs Detido por 87 ETFs

O peso reflete apenas participações diretas em ações (N-PORT); fundos alavancados ou baseados em derivativos podem deter exposição adicional a swaps não mostrada.

Fundo Peso Unidades Em Fonte
IBRN · iShares Trust 3,81% 4.145 SH 8 de Agosto de 2026 Diário
PSCH · Invesco Exchange-Traded Fund Trust … 3,08% 71.992 SH 8 de Agosto de 2026 Diário
PBE · Invesco Exchange-Traded Fund Trust 2,59% 128.216 SH 8 de Agosto de 2026 Diário
XSMO · Invesco Exchange-Traded Fund Trust 1,52% 642.023 SH 8 de Agosto de 2026 Diário
BBP · ETFis Series Trust I 1,37% 12.510 NS 30 de Abril de 2026 N-PORT
SIXS · EXCHANGE TRADED CONCEPTS TRUST 1,30% 22.380 NS 31 de Maio de 2026 N-PORT
RZG · Invesco Exchange-Traded Fund Trust 1,25% 23.662 SH 8 de Agosto de 2026 Diário
GURU · Global X Funds 1,03% 9.268 NS 30 de Abril de 2026 N-PORT
LABU · Direxion Shares ETF Trust 0,93% 73.928 NS 30 de Abril de 2026 N-PORT
VAMO · Cambria ETF Trust 0,83% 10.625 NS 30 de Abril de 2026 N-PORT
VIOG · VANGUARD ADMIRAL FUNDS 0,74% 98.733 SH 8 de Agosto de 2026 Diário
VMAX · Lattice Strategies Trust 0,72% 5.120 NS 30 de Abril de 2026 N-PORT
IJT · iShares Trust 0,66% 770.376 SH 8 de Agosto de 2026 Diário
FNY · First Trust Exchange-Traded AlphaDE… 0,51% 40.257 NS 30 de Abril de 2026 N-PORT
MMSC · First Trust Exchange-Traded Fund VI… 0,49% 3.490 NS 31 de Maio de 2026 N-PORT
CLSE · Trust for Professional Managers 0,49% 40.488 NS 31 de Maio de 2026 N-PORT
IBB · iShares Trust 0,44% 588.017 SH 8 de Agosto de 2026 Diário
HQGO · Lattice Strategies Trust 0,43% 3.203 NS 30 de Abril de 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0,41% 4.514 SH 8 de Agosto de 2026 Diário
OASC · Unified Series Trust 0,40% 4.569 NS 31 de Maio de 2026 N-PORT
BRNY · EA Series Trust 0,40% 34.057 NS 30 de Abril de 2026 N-PORT
VIOO · VANGUARD ADMIRAL FUNDS 0,37% 290.018 SH 8 de Agosto de 2026 Diário
XJR · iShares Trust 0,37% 9.802 SH 8 de Agosto de 2026 Diário
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,34% 35.034 NS 31 de Maio de 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0,34% 75.795 SH 8 de Agosto de 2026 Diário
ESSC · Strategy Shares 0,34% 1.335 NS 30 de Abril de 2026 N-PORT
IJR · iShares Trust 0,32% 5.058.562 SH 8 de Agosto de 2026 Diário
IWO · iShares Trust 0,31% 641.280 SH 8 de Agosto de 2026 Diário
BIB · ProShares Trust 0,31% 3.062 NS 31 de Maio de 2026 N-PORT
FSCC · Federated Hermes ETF Trust 0,31% 11.451 NS 31 de Maio de 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0,30% 39.411 NS 31 de Maio de 2026 N-PORT
SAA · ProShares Trust 0,26% 961 NS 31 de Maio de 2026 N-PORT
ROUS · Lattice Strategies Trust 0,25% 22.443 NS 30 de Abril de 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0,24% 27.276 NS 30 de Abril de 2026 N-PORT
BKSE · BNY Mellon ETF Trust 0,23% 2.877 NS 30 de Abril de 2026 N-PORT
AFSM · First Trust Exchange-Traded Fund VI… 0,23% 3.003 NS 31 de Maio de 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0,20% 477.030 SH 8 de Agosto de 2026 Diário
FNX · First Trust Exchange-Traded AlphaDE… 0,20% 39.967 NS 30 de Abril de 2026 N-PORT
VBK · VANGUARD INDEX FUNDS 0,19% 1.099.640 SH 8 de Agosto de 2026 Diário
PRFZ · Invesco Exchange-Traded Fund Trust 0,18% 72.691 SH 8 de Agosto de 2026 Diário
IWM · iShares Trust 0,18% 2.102.256 SH 8 de Agosto de 2026 Diário
LRGF · iShares Trust 0,16% 84.151 SH 8 de Agosto de 2026 Diário
ISCG · iShares Trust 0,16% 22.792 SH 8 de Agosto de 2026 Diário
RSSL · Global X Funds 0,16% 34.125 NS 30 de Abril de 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0,15% 11.071 NS 30 de Abril de 2026 N-PORT
ITWO · ProShares Trust 0,15% 3.710 NS 31 de Maio de 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0,14% 35.428 SH 8 de Agosto de 2026 Diário
FSMD · FIDELITY COVINGTON TRUST 0,14% 49.932 NS 30 de Abril de 2026 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0,14% 5.350 SH 8 de Agosto de 2026 Diário
SMDX · Tidal Trust III 0,13% 2.579 NS 30 de Abril de 2026 N-PORT