SLS SELLAS Life Sciences Group, Inc. - Common Stock

NASDAQ · Biotechnology · Ver em SEC EDGAR ↗
$13,06
Preço · Ago 19, 2026
Fundamentais a partir de Ago 11, 2026

Sobre SELLAS Life Sciences Group, Inc. - Common Stock Visão geral da empresa da Wikipedia

Galena Biopharma, Inc. was a publicly traded pharmaceutical company based in San Ramon, California. The company was founded in Worcester, Massachusetts. In 2011, it moved to Oregon, and in 2015 moved to San Ramon, California. Mark Schwartz was the company's president and chief executive officer. As of December 29, 2017, the company was acquired by Sellas Life Sciences Group Ltd. through a reverse merger transaction. Galena Biopharma was renamed to Sellas Life Sciences Group, Inc..

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Galena Biopharma, Inc. (originally RXi Pharmaceuticals) was a publicly traded pharmaceutical company based in San Ramon, California. The company was founded in Worcester, Massachusetts. In 2011, it moved to Oregon, and in 2015 moved to San Ramon, California. Mark Schwartz was the company's president and chief executive officer. As of December 29, 2017, the company was acquired by Sellas Life Sciences Group Ltd. through a reverse merger transaction. Galena Biopharma was renamed to Sellas Life Sciences Group, Inc. (Nasdaq: SLS).

History

In November 2006, Argonaut Pharmaceuticals, Inc. changed the name to RXi Pharmaceuticals Corporation. RXi was a subsidiary of CytRx Corp., which provided $15 million in financing in April 2007. RXi was founded in part by Nobel Prize winner Craig Mello. In September 2007, RXi signed a licensing deal with TriLink Biotechnologies, a competitor in the RNA interference (RNAi) field, in which RXi would pay TriLink to use three of TriLink's technologies.

In March 2011, the company announced the planned acquisition of Arizona-based Apthera, Inc. for $7 million. The acquisition included the breast cancer drug NeuVax. In June 2011, NeuVax was approved by the United States Food and Drug Administration to start a stage three clinical trial.

In September 2011, the company separated its cancer therapies division. It was renamed Galena Biopharma Inc and moved to Lake Oswego, Oregon. RXi became a subsidiary of Galena and retained RNAi technologies. RXi Pharmaceuticals remained in Massachusetts as a publicly traded company. In January 2014, Galena bought Mills Pharmaceuticals. In April 2014, the company headquarters moved to Portland.

In November 2011, the company partnered with Genentech to combine drugs from each company for a cancer treatment. Galena is currently studying the combination of NeuVax and Herceptin in phase II trials.

Leadership

In March 2011, president and CEO Noah Beerman were replaced by Mark Ahn, and in August 2014, Ahn resigned and was replaced by Mark Schwartz. On January 31, 2017, Galena announced the resignation of Mark Schwartz effective that day, and reported in the same press release that it would be exploring strategic alternatives to maximize shareholder value going forward.

Stock

RXi went public in March 2008. CytRx retained 49% ownership of RXi's stock and gave shares of RXi to existing shareholders. Trading began on the Nasdaq market on March 12, 2008, under the ticker symbol of RXII. Fidelity Investments invested $8.5 million in the company in May 2008, followed by a $25 million private-equity investment by Yorkville in February 2009. In 2010, RXi received a National Institutes of Health grant of $600,000. By August 2010, the company had 30 employees. In April 2011, RXi raised about $12 million from a stock offering and received $580,000 in grants from the National Institutes of Health. The company reported a loss of $11.5 million loss for 2011.

In November 2012, an anonymous internet report caused Galena stock to decline. The company filed a lawsuit claiming the report was false and attempted to manipulate the stock. In 2014, Galena's involvement in a fraudulent stock promotion scheme was exposed. On February 1, 2014, analyst Matt Gravitt published an article that revealed Galena had paid MissionIR, DreamTeam brand, to promote Galena's stock. Galena's stock fell 20% following this revelation that received a heated response, and was one of the three most read articles in Seeking Alpha's history. Over the next few weeks, more revelations came out and the company admitted their stock promotion relationship and insider selling. Galena then disclosed that the SEC was investigation their relationship with The DreamTeam Group. By March 2014, five lawsuits were filed against Galena and several of its officers alleging that the company used misleading articles to boost stock prices. Motley Fool, discussing the 23% stock price drop during March 2015, noted there was stock dilution from the offering and also that Abstral's sales were below Galena's estimates from late 2013. Discussing the Motley Fool article, Portland Business Journal also noted the ongoing insider-trading lawsuits as a factor in the stock price. A few days later, Zacks Investment Research said Galena could be a "great candidate" to beat its earnings. In response, Galena's CEO said there were many positive aspects to the company, and that the lawsuits weren't a worry as they should get covered under Directors and officers liability insurance. The company moved to San Ramon, California, in the Bay Area in 2015.

Stock promotion scandal

The revelation that Galena was engaging in fraudulent stock promotion without adequate disclosure led to the investigation of other biotech companies who engaged in similar activities. Richard Pearson, an investor who went undercover to investigate the stock promotion firms, wrote an exposé on DreamTeam and its ties to articles about Galena, CytRx, and other companies on media websites. In April 2017, the Securities and Exchange Commission announced enforcement actions against 27 individuals and entities behind various alleged stock promotion schemes. Fraud charges were filed against three public companies, seven stock promotion or communications firms, and two company CEOs; also on this hit list are six individuals and nine writers.

Merger with Sellas Life Sciences

In 2017, Galena Biopharma Inc. announced a merger "with privately-held oncology company Sellas Life Sciences Group Ltd. in an all-stock transaction." The combined company was Sellas Life Science Group. The newly merged companies focused on the development of novel treatments for cancer.

Products

Galena acquired the experimental breast cancer drug NeuVax in 2011 and are currently in phase II trials to combine the drug with Genentech's Herceptin.

In 2013, Galena began selling its first developed drug, an analgesic for cancer pain named Abstral Sublingual.

Anagrelide controlled-released (GALE-401) was approved by the FDA for phase III clinical trials for the treatment of essential thrombocytosis in December 2016.

GALE-301 and GALE-302 are immunotherapies in phase I and II trials for ovarian and breast cancers.

== References ==

Fonte: Wikipedia (Inglês), CC BY-SA 4.0 · Ver na Wikipedia ↗

Wikidata ↗

SLS Instantâneo da Ação Preço, capitalização de mercado, P/E, EPS, ROE, dívida/patrimônio, intervalo de 52 semanas

Preço
$13.06
Capitalização de Mercado
$2.37B
P/E (TTM)
-61.9
EPS (TTM)
$-0.25
Receita (TTM)
$0
Rendimento div.
ROE
-55.4%
Dívida/Capital
Intervalo 52 Semanas
$1 – $16

SLS Gráfico de Preço da Ação OHLCV diário com indicadores técnicos — panorâmica, zoom e personalize sua visualização

Desempenho de 10 Anos Tendências de receita, lucro líquido, margens e EPS

Receita e Lucro Líquido $0
5-point trend, +0.00
2019-12-31 2023-12-31
EPS $-0.25
6-point trend, +88.2%
2020-12-31 2025-12-31
Fluxo de caixa livre
2016-12-31 2016-12-31
Margens

Avaliação Rácios P/E, P/S, P/B, EV/EBITDA — a ação está cara ou barata?

Métrica
Tendência de 5 anos
SLS
Mediana de Pares
P/E (TTM)
5-point trend, -265.4%
-61.9
55.4
P/B
5-point trend, +88.5%
33.4
6.4

Lucratividade Margens bruta, operacional e líquida; ROE, ROA, ROIC

Métrica
Tendência de 5 anos
SLS
Mediana de Pares
ROA
5-point trend, +4.0%
-54.9%
-32.7%
ROE
5-point trend, +37.2%
-55.4%
-37.9%
ROIC
5-point trend, +67.5%
-39.9%

Saúde financeira Dívida, liquidez, solvência — força do balanço patrimonial

Métrica
Tendência de 5 anos
SLS
Mediana de Pares
Current Ratio (Índice de liquidez corrente)
5-point trend, +131.7%
10.7
9.7
Quick Ratio (Índice de Liquidez Seca)
5-point trend, +138.7%
10.2

Crescimento Crescimento da receita, EPS e lucro líquido: YoY, CAGR 3 anos, CAGR 5 anos

Métrica
Tendência de 5 anos
SLS
Mediana de Pares

Métricas por Ação EPS, valor patrimonial por ação, fluxo de caixa por ação, dividendo por ação

Métrica
Tendência de 5 anos
SLS
Mediana de Pares
EPS (Diluted) (EPS (Diluído))
5-point trend, +81.3%
$-0.25

Eficiência de Capital Giro de ativos, giro de estoques, giro de contas a receber

Métrica
Tendência de 5 anos
SLS
Mediana de Pares

SLS Consenso dos analistas Opiniões de analistas otimistas e pessimistas, preço-alvo de 12 meses, potencial de alta

COMPRA 6 analistas
  • Compra forte 1 16,7%
  • Compra 4 66,7%
  • Manter 1 16,7%
  • Venda 0 0,0%
  • Venda forte 0 0,0%

Preço-alvo de 12 meses

2 analistas · 2026-08-14
Alvo mediano $27.50 +110,5%
Alvo médio $27.50 +110,5%

Histórico de Lucros EPS real vs. estimativa, surpresa %, taxa de acerto, próxima data de resultados

Surpresa Média
0.02%
Período EPS Actual EPS est. Surpresa
31 de Março de 2026 $-0.05 $-0.04 -0.01%
31 de Dezembro de 2025 $-0.05 $-0.07 0.02%
30 de Setembro de 2025 $-0.06 $-0.07 0.01%
30 de Junho de 2025 $-0.07 $-0.08 0.01%
31 de Março de 2025 $-0.07 $-0.11 0.04%
31 de Dezembro de 2024 $-0.08 $-0.11 0.03%

Comparação de pares (subindústria GICS) Métricas chave vs pares do setor

Ticker Capitalização de Mercado P/E Receita YoY Margem Líquida ROE Margem Bruta
SLS $577M -15.1 -55.4%
NRIX $1.80B -5.8 53.9% -314.9% -53.6%
BEAM $2.82B -34.2 120.0% -57.2% -7.0%
KOD $1.73B -6.5 -202.0%
RARE $2.22B -3.9 20.2% -85.4% -1613.2%
BCRX $1.66B 6.4 94.1% 30.2% -97.6%
COAG
KLRA
CDNA $959M -47.1 13.8% -5.6% -6.8%
PGEN $1.48B -3.1 146.7% -2588.2% 3159.1%

Fundamentos Completos Todas as métricas por ano — demonstração de resultados, balanço patrimonial, fluxo de caixa

Demonstração de Resultados 15
Dados anuais de Demonstração de Resultados para SLS
Métrica Tendência 202520242023202220212020201920182017201620152014
Revenue 6-point trend, -100.0% · · $0 $1M $8M $2M $0 · · · · $9M
Cost of Revenue 7-point trend, -100.0% $0 $0 $0 $100.0K $200.0K $0 · · · · · $1M
R&D Expense 6-point trend, +37.6% · · · · $16M $9M $7M $9M $6M $11M · ·
SG&A Expense 10-point trend, +166.8% $12M $12M $14M $13M $11M $10M $10M $13M $15M $5M · ·
Operating Expenses 12-point trend, -35.6% $28M $32M $38M $43M $33M $19M $20M $31M $23M $32M $34M $44M
Operating Income 11-point trend, +35.6% $-28M $-32M $-38M $-42M $-25M $-17M $-20M · $-23M $-16M $-34M $-44M
Other Non-op 12-point trend, +730.0% $1M $632.0K $529.0K $649.0K $4M $208.0K $-19M $-29M $-24M $5M $509.0K $170.0K
Pretax Income 12-point trend, +5.0% $-27M $-31M $-37M $-41M $-21M $-17M $-19M $-29M $-24M $-18M $-39M $-28M
Income Tax 12-point trend, +0.00 $0 $0 $0 $0 $-237.0K $-17.0K $-81.0K $-1M $300.0K $1.0K $365.0K $0
Net Income 12-point trend, +26.6% $-27M $-31M $-37M $-41M $-21M $-17M $-19M $-28M $-24M $-18M $-64M $-37M
EPS (Basic) 6-point trend, +88.2% $-0.25 $-0.50 $-1.34 $-2.13 $-1.34 $-2.11 · · · · · ·
EPS (Diluted) 6-point trend, +88.2% $-0.25 $-0.50 $-1.34 $-2.13 $-1.34 $-2.11 · · · · · ·
Shares (Basic) 6-point trend, +1267.1% 109,051,215 61,202,412 27,777,111 19,395,709 15,481,113 7,977,104 · · · · · ·
Shares (Diluted) 6-point trend, +1267.1% 109,051,215 61,202,412 27,777,111 19,395,709 15,481,113 7,977,104 · · · · · ·
EBITDA 8-point trend, +10.9% $-28M $-32M $-38M $-42M $-25M $-17M · · $-23M $-32M · ·
Balanço Patrimonial 22
Dados anuais de Balanço Patrimonial para SLS
Métrica Tendência 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +203.6% $72M $14M $3M $17M $21M $35M $7M $5M $2M $6M $1M $24M
Receivables 2-point trend, -100.0% · · · · $0 · · · · · · $2M
Inventory 2-point trend, -100.0% · · · · · · · · · · $0 $655.0K
Prepaid Expense 12-point trend, +168.2% $3M $2M $542.0K $531.0K $2M $395.0K $557.0K $387.0K $337.0K $332.0K $1M $1M
Current Assets 12-point trend, +44.4% $75M $16M $3M $18M $23M $37M $8M $6M $13M $6M $54M $52M
PP&E (Net) 3-point trend, -30.2% · · · · · · · · · $199.0K $335.0K $285.0K
Goodwill 12-point trend, -67.5% $2M $2M $2M $2M $2M $2M $2M $2M $2M $6M $6M $6M
Total Assets 12-point trend, -2.7% $78M $19M $6M $21M $26M $46M $17M $17M $34M $6M $82M $80M
Accounts Payable 12-point trend, +56.3% $3M $4M $6M $3M $2M $5M $4M $4M $12M $840.0K $2M $2M
Accrued Liabilities 12-point trend, -60.3% $4M $5M $8M $6M $3M $2M $1M $2M $3M $4M $5M $9M
Current Liabilities 12-point trend, -74.2% $7M $10M $14M $16M $5M $12M $5M $6M $25M $6M $57M $27M
Capital Leases 8-point trend, +457000.00 $457.0K $457.0K $460.0K $573.0K $610.0K $825.0K $0 $0 · · · ·
Deferred Tax 5-point trend, -100.0% · · · · $0 $239.0K $262.0K $357.0K $2M · · ·
Total Liabilities 12-point trend, -82.8% $7M $10M $14M $16M $6M $18M $11M $12M $31M $11M $69M $43M
Long-term Debt 4-point trend, -100.0% · · · · · · · $0 $11M · $5M $8M
Total Debt 2-point trend, -33.0% · · · · · · · · $11M $16M · ·
Common Stock 12-point trend, +25.0% $15.0K $7.0K $3.0K $2.0K $2.0K $1.0K $1.0K $1.0K $1.0K $2.0K $15.0K $12.0K
Retained Earnings 10-point trend, -803.6% $-275M $-248M $-217M $-180M $-139M $-118M $-101M $-82M $-54M $-30M · ·
Treasury Stock Flat — no change across 3 periods · · · · · · · · · $4M $4M $4M
Stockholders' Equity 12-point trend, +91.2% $71M $9M $-8M $5M $20M $28M $6M $5M $2M $-5M $-12M $37M
Liabilities + Equity 12-point trend, -2.7% $78M $19M $6M $21M $26M $46M $17M $17M $34M $6M $82M $80M
Shares Outstanding 12-point trend, +39.9% 153,103,459 73,977,459 32,132,890 21,005,405 15,895,637 14,254,554 5,080,100 440,529 5,766,891 1,268,489 8,095,337 109,425,701
Fluxo de Caixa 17
Dados anuais de Fluxo de Caixa para SLS
Métrica Tendência 202520242023202220212020201920182017201620152014
D&A 3-point trend, -96.5% · · · · · · · · · $3.0K $107.0K $86.0K
Stock-based Comp 12-point trend, -58.1% $2M $2M $2M $2M $1M $578.0K $573.0K $395.0K $3M $354.0K $2M $5M
Deferred Tax 9-point trend, +0.00 · · · $0 $-239.0K $-22.0K $-95.0K $-1M $39.0K $-41.0K $365.0K $0
Amort. of Intangibles 3-point trend, -100.0% · · · · · · · $0 $2M · · $440.0K
Other Non-cash · · · · · · · · · $-24M · ·
Operating Cash Flow 12-point trend, +33.8% $-28M $-35M $-31M $-24M $-26M $-10M $-18M $-30M $-11M $-12M $-48M $-43M
CapEx 3-point trend, -89.5% · · · · · · · · · $6.0K $153.0K $57.0K
Investing Cash Flow 9-point trend, +100.0% · $0 $-6M $-4M $0 · · $0 $12M $-85.0K $10M $-6M
Debt Issued 3-point trend, +1500000.00 · · · · · · · · · $2M $0 $0
Net Debt Issued 2-point trend, -100.0% · · · · · · $0 · · $18M · ·
Stock Issued 11-point trend, -100.0% · $0 $289.0K $1M $9M $30M $16M $22M $6M $34M $47M $11M
Net Stock Activity 8-point trend, -100.0% · $0 $289.0K $1M $9M $30M $16M · $6M $34M · ·
Dividends Paid 3-point trend, +0.00 · · · · · · $0 $487.0K $0 · · ·
Financing Cash Flow 12-point trend, +255.7% $86M $47M $22M $24M $12M $38M $20M $23M $6M $16M $44M $24M
Net Change in Cash 12-point trend, +339.9% $58M $11M $-15M $-4M $-14M $28M $2M $-7M $7M $5M $6M $-24M
Taxes Paid Flat — no change across 2 periods $0 $0 · · · · · · · · · ·
Free Cash Flow · · · · · · · · · $-45M · ·
Lucratividade 7
Dados anuais de Lucratividade para SLS
Métrica Tendência 202520242023202220212020201920182017201620152014
Operating Margin 4-point trend, -184.1% · · · -4195.0% -332.8% -893.8% · · 4986.8% · · ·
Net Margin 5-point trend, -180.3% · · · -4130.1% -272.4% -881.9% -16349.1% · 5141.6% · · ·
Pretax Margin 5-point trend, -181.2% · · · -4130.1% -275.5% -882.8% -16417.0% · 5086.8% · · ·
EBITDA Margin 4-point trend, -184.1% · · · -4195.0% -332.8% -893.8% · · 4986.8% · · ·
ROA 9-point trend, -72.6% -54.9% -240.8% -274.9% -174.9% -57.2% -53.5% -115.1% · -118.9% -31.8% · ·
ROE 9-point trend, +80.7% -55.4% -243.6% 632.7% -473.4% -88.2% -93.3% -340.3% · 1623.1% -287.3% · ·
ROIC 8-point trend, +44.8% -39.9% -332.9% 474.8% -864.8% -122.9% -60.7% · · -178.3% -72.3% · ·
Liquidez e Solvência 4
Dados anuais de Liquidez e Solvência para SLS
Métrica Tendência 202520242023202220212020201920182017201620152014
Current Ratio 9-point trend, +768.9% 10.7 1.7 0.2 1.1 4.6 3.0 1.6 · 0.5 1.2 · ·
Quick Ratio 9-point trend, +1619.8% 10.2 1.5 0.2 1.1 4.3 2.9 1.4 · 0.1 0.6 · ·
Debt / Equity 2-point trend, +827.7% · · · · · · · · 5.3 0.6 · ·
LT Debt / Equity · · · · · · · · 1.3 · · ·
Eficiência 1
Dados anuais de Eficiência para SLS
Métrica Tendência 202520242023202220212020201920182017201620152014
Asset Turnover 6-point trend, +100.0% · · 0.0 0.0 0.2 0.1 0.0 · -0.0 · · ·
Por Ação 5
Dados anuais de Por Ação para SLS
Métrica Tendência 202520242023202220212020201920182017201620152014
Book Value / Share 9-point trend, -75.5% $0.46 $0.13 $-0.25 $0.23 $1.28 $1.96 $1.20 · $0.36 $1.89 · ·
Revenue / Share 3-point trend, -100.0% · · $0.00 $0.05 $0.49 · · · · · · ·
Cash Flow / Share 5-point trend, +84.5% $-0.26 $-0.58 $-1.13 $-1.23 $-1.68 · · · · · · ·
Cash / Share 9-point trend, -60.6% $0.47 $0.19 $0.08 $0.82 $1.34 $2.48 $1.43 · $0.40 $1.19 · ·
EPS (TTM) 6-point trend, +88.2% $-0.25 $-0.50 $-1.34 $-2.13 $-1.34 $-2.11 · · · · · ·
Taxas de Crescimento 1
Dados anuais de Taxas de Crescimento para SLS
Métrica Tendência 202520242023202220212020201920182017201620152014
Revenue YoY 2-point trend, -128.9% · · · -86.8% 300.0% · · · · · · ·
Avaliação (TTM) 17
Dados anuais de Avaliação (TTM) para SLS
Métrica Tendência 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -100.0% $0 $0 $0 $1M $8M $2M $0 $10M $10M $10M $10M $9M
Net Income TTM 12-point trend, +26.6% $-27M $-31M $-37M $-41M $-21M $-17M $-19M $-28M $-24M $-18M $-64M $-37M
Market Cap 9-point trend, -98.7% $577M $77M $34M $50M $88M $83M $22M · $2.25B $44.20B · ·
Enterprise Value 2-point trend, -94.9% · · · · · · · · $2.26B $44.20B · ·
P/E 6-point trend, -447.6% -15.1 -2.1 -0.8 -1.1 -4.1 -2.8 · · · · · ·
P/S 5-point trend, -98.9% · · · 49.6 11.6 43.6 · · 223.1 4384.0 · ·
P/B 9-point trend, -99.5% 8.1 8.1 -4.3 10.2 4.3 3.0 3.6 · 1086.5 1542.5 · ·
P / Tangible Book 5-point trend, +163.3% 8.4 10.2 · 16.9 4.8 3.2 · · · · · ·
P / Cash Flow 9-point trend, +97.9% -20.3 -2.2 -1.1 -2.1 -3.4 -8.0 -1.2 · -204.7 -984.2 · ·
P / FCF · · · · · · · · · -984.0 · ·
EV / EBITDA 2-point trend, +93.0% · · · · · · · · -98.0 -1393.3 · ·
EV / FCF · · · · · · · · · -984.0 · ·
EV / Revenue 2-point trend, -94.9% · · · · · · · · 223.9 4383.9 · ·
Dividend Yield Flat — no change across 2 periods · · · · · · 0.00% · 0.00% · · ·
Earnings Yield 6-point trend, +81.7% -6.6% -48.1% -126.4% -90.2% -24.2% -36.3% · · · · · ·
Payout Ratio · · · · · · 0.00% · · · · ·
Annual Payout 3-point trend, +0.00 · · · · · · $0 $487.0K $0 · · ·

Demonstrações Financeiras Demonstração de resultados, balanço patrimonial, fluxo de caixa — anual, últimos 5 anos

Demonstração de Resultados
2025-12-312024-12-312023-12-312022-12-312021-12-31
Receita $0$1M$8M
Margem Operacional % -4195.0%-332.8%
Lucro líquido $-27M$-31M$-37M$-41M$-21M
EPS Diluído $-0.25$-0.50$-1.34$-2.13$-1.34
Balanço Patrimonial
2025-12-312024-12-312023-12-312022-12-312021-12-31
Índice de liquidez corrente 10.71.70.21.14.6
Índice de Liquidez Seca 10.21.50.21.14.3

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Investidores institucionais (13F) 231 declarantes · $1.2B total · Em 30 de Junho de 2026

Instituições que relatam a posse desta ação em seu Formulário 13F trimestral da SEC. Apenas posições compradas; um único declarante pode aparecer duas vezes para opções separadas. Grandes posições de compra/venda compensatórias geralmente refletem market-making ou inventário protegido, não convicção direcional.

Atividade institucional — Q2 2026 vs trimestre anterior
Novas posições Posições encerradas Aumentou Diminuído Variação líquida de ações
87 (+24 vs trimestre anterior) 19 (+4 vs trimestre anterior) 70 (+12 vs trimestre anterior) 38 (+15 vs trimestre anterior) +39.9M

Comparado a Q1 2026. Os registros do Formulário 13F da SEC devem ser feitos em até 45 dias após o final do trimestre, mais um pequeno período de tolerância para registrantes atrasados — trimestres ainda dentro desse período são ignorados em favor do par mais recente totalmente reportado.

Instituição Valor Ações % de 13F rastreado Tipo
STATE STREET CORP $191.829.196 12.996.558 15,97% Ações
VANGUARD CAPITAL MANAGEMENT LLC $121.417.310 8.226.105 10,11% Ações
SUSQUEHANNA INTERNATIONAL GROUP, LLP $105.640.272 7.157.200 8,79% Opção de compra
Anson Funds Management LP $66.420.000 4.500.000 5,53% Ações
CITADEL ADVISORS LLC $64.157.292 4.346.700 5,34% Opção de compra
GEODE CAPITAL MANAGEMENT, LLC $61.905.400 4.193.009 5,15% Ações
SUSQUEHANNA INTERNATIONAL GROUP, LLP $61.832.592 4.189.200 5,15% Opção de venda
CITADEL ADVISORS LLC $33.333.984 2.258.400 2,77% Opção de venda
VANGUARD PORTFOLIO MANAGEMENT LLC $31.897.821 2.161.099 2,66% Ações
SUSQUEHANNA INTERNATIONAL GROUP, LLP $30.266.812 2.050.597 2,52% Ações
JONES FINANCIAL COMPANIES LLLP $28.553.511 2.304.561 2,38% Ações
VANGUARD GROUP INC $27.868.421 7.392.154 2,32% Ações
Anson Funds Management LP $27.245.484 1.845.900 2,27% Opção de venda
PERCEPTIVE ADVISORS LLC $22.140.000 1.500.000 1,84% Opção de venda
VANGUARD FIDUCIARY TRUST CO $19.707.050 1.335.166 1,64% Ações
Sio Capital Management, LLC $18.165.132 1.230.700 1,51% Opção de venda
BNP PARIBAS FINANCIAL MARKETS $15.823.045 1.072.022 1,32% Ações
MILLENNIUM MANAGEMENT LLC $13.372.560 906.000 1,11% Opção de venda
BARCLAYS PLC $11.831.616 801.600 0,98% Opção de venda
Anson Funds Management LP $11.808.000 800.000 0,98% Opção de compra
BNP PARIBAS FINANCIAL MARKETS $11.734.200 7.950 0,98% Opção de venda
JANE STREET GROUP, LLC $11.058.192 749.200 0,92% Opção de compra
MORGAN STANLEY $9.922.380 672.248 0,83% Ações
BANK OF AMERICA CORP /DE/ $9.150.359 619.943 0,76% Ações
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $8.339.518 565.008 0,69% Ações
JANE STREET GROUP, LLC $7.462.700 505.603 0,62% Ações
Balyasny Asset Management L.P. $7.380.000 500.000 0,61% Opção de venda
LMR Partners LLP $6.642.000 450.000 0,55% Opção de venda
NOMURA HOLDINGS INC $6.273.000 425.000 0,52% Opção de compra
DIADEMA PARTNERS LP $5.904.000 400.000 0,49% Opção de compra
Swiss National Bank $5.319.504 360.400 0,44% Ações
XTX Topco Ltd $5.300.168 359.090 0,44% Ações
Ikarian Capital, LLC $5.235.372 354.700 0,44% Opção de venda
CITIGROUP INC $4.659.717 315.699 0,39% Ações
RENAISSANCE TECHNOLOGIES LLC $4.580.973 310.364 0,38% Ações
DAGCO, INC. $4.351.740 1.028.780 0,36% Ações
Everhart Financial Group, Inc. $4.251.146 288.018 0,35% Ações
Rafferty Asset Management, LLC $3.540.806 239.892 0,29% Ações
RHUMBLINE ADVISERS $3.400.726 230.402 0,28% Ações
Walleye Capital LLC $3.377.088 228.800 0,28% Opção de venda
GOLDMAN SACHS GROUP INC $3.125.991 211.788 0,26% Ações
TUDOR INVESTMENT CORP ET AL $3.087.792 209.200 0,26% Opção de venda
WELLINGTON MANAGEMENT GROUP LLP $2.992.738 202.760 0,25% Ações
BOOTHBAY FUND MANAGEMENT, LLC $2.982.996 202.100 0,25% Opção de venda
Jefferies Financial Group Inc. $2.958.775 200.459 0,25% Ações
Jefferies Financial Group Inc. $2.953.476 200.100 0,25% Opção de venda
Mariner, LLC $2.925.609 198.212 0,24% Ações
MILLENNIUM MANAGEMENT LLC $2.895.912 196.200 0,24% Opção de compra
Bank of New York Mellon Corp $2.801.212 189.784 0,23% Ações
ALPS ADVISORS INC $2.776.459 188.107 0,23% Ações
JANE STREET GROUP, LLC $2.405.880 163.000 0,20% Opção de venda
LPL Financial LLC $2.297.586 155.663 0,19% Ações
SIMPLEX TRADING, LLC $2.274.501 154.099 0,19% Ações
BlackRock, Inc. $2.222.708 150.590 0,19% Ações
WELLS FARGO & COMPANY/MN $2.208.775 149.646 0,18% Ações
Vontobel Holding Ltd. $2.166.207 146.762 0,18% Ações
TUDOR INVESTMENT CORP ET AL $2.069.352 140.200 0,17% Opção de compra
Vanguard Global Advisers, LLC $1.918.874 130.005 0,16% Ações
VANGUARD ASSET MANAGEMENT, Ltd $1.859.598 125.989 0,15% Ações
Caption Management, LLC $1.845.000 125.000 0,15% Opção de venda
PROFUND ADVISORS LLC $1.780.159 120.607 0,15% Ações
MetLife Investment Management, LLC $1.624.810 110.082 0,14% Ações
Daiwa Securities Group Inc. $1.589.652 107.700 0,13% Opção de venda
Daiwa Securities Group Inc. $1.512.900 102.500 0,13% Ações
DIADEMA PARTNERS LP $1.476.000 100.000 0,12% Opção de venda
HIGHBRIDGE CAPITAL MANAGEMENT LLC $1.467.144 99.400 0,12% Ações
STATE OF WISCONSIN INVESTMENT BOARD $1.405.300 95.210 0,12% Ações
Harvest Investment Services, LLC $1.394.554 94.482 0,12% Ações
ORBIMED ADVISORS LLC $1.365.300 92.500 0,11% Opção de venda
Zurcher Kantonalbank (Zurich Cantonalbank) $1.229.582 83.305 0,10% Ações
Invesco Ltd. $1.104.816 74.852 0,09% Ações
Gotham Asset Management, LLC $1.097.317 74.344 0,09% Ações
FULCRUM WEALTH ADVISORS, LLC $1.081.214 73.253 0,09% Ações
ALLIANCEBERNSTEIN L.P. $998.534 236.060 0,08% Ações
NEW YORK STATE COMMON RETIREMENT FUND $978.588 66.300 0,08% Ações
Verition Fund Management LLC $916.596 62.100 0,08% Opção de venda
OSAIC HOLDINGS, INC. $889.776 60.284 0,07% Ações
FIFTH THIRD BANCORP $888.404 60.190 0,07% Ações
State of New Jersey Common Pension Fund D $857.069 58.067 0,07% Ações
Verition Fund Management LLC $832.464 56.400 0,07% Opção de compra
Police & Firemen's Retirement System of New Jersey $821.630 55.666 0,07% Ações
ARIZONA STATE RETIREMENT SYSTEM $731.388 49.552 0,06% Ações
Caption Management, LLC $728.745 49.373 0,06% Ações
MANUFACTURERS LIFE INSURANCE COMPANY, THE $722.310 48.937 0,06% Ações
Russell Investments Group, Ltd. $704.494 47.730 0,06% Ações
SIG BROKERAGE, LP $689.292 46.700 0,06% Opção de compra
Vanguard Investments Australia, Ltd. $684.643 46.385 0,06% Ações
COMMONWEALTH EQUITY SERVICES, LLC $665.481 45.087 0,06% Ações
INSTRUMENTAL WEALTH, LLC $662.931 44.914 0,06% Ações
Persistent Asset Partners Ltd $655.647 758 0,05% Opção de compra
Virtus Investment Advisers, LLC $616.791 41.788 0,05% Ações
Accurate Wealth Management, LLC $614.707 47.462 0,05% Ações
AXXCESS WEALTH MANAGEMENT, LLC $610.665 41.373 0,05% Ações
KLP KAPITALFORVALTNING AS $600.732 40.700 0,05% Ações
SJS Investment Consulting Inc. $590.400 40.000 0,05% Ações
Wealthfront Advisers LLC $587.773 39.822 0,05% Ações
Quantinno Capital Management LP $546.651 37.036 0,05% Ações
Visionary Horizons, LLC $531.360 36.000 0,04% Ações
Kestra Advisory Services, LLC $516.305 34.980 0,04% Ações
NORTHSTAR ASSET MANAGEMENT Co $509.400 45.000 0,04% Ações

Executivos da empresa 42 insiders · 17 diretores · 9 conselheiros

Investidor com informação privilegiada Função Última atividade Ações detidas Compras 12m Vendas 12m Líquido 12m
Andelos M. Stergiou President and CEO 16 de Junho de 2026 A 1.759.183 0 0 $0
Noah D Beerman CEO and President 15 de Março de 2011 A 92.994 0 0 $0
John Thomas Burns CFO 7 de Janeiro de 2026 A 554.327 0 0 $0
Gene Mack CFO and Treasurer 20 de Abril de 2018 A 0 0 $0
Robert Eugene Kennedy Vice President and CFO 13 de Abril de 2011 A 379.294 0 0 $0
Stephen J. Dipalma CFO, EVP, Secretary 15 de Janeiro de 2009 A 0 0 $0
Dragan Cicic SVP, Chief Development Officer 7 de Janeiro de 2026 A 557.805 0 0 $0
Robert Francomano Chief Commercial Officer 22 de Janeiro de 2024 A 40.918 0 0 $0
Barbara A Wood EVP, Gen. Counsel, Corp. Sec. 22 de Janeiro de 2024 A 117.225 0 0 $0
Nicholas J. Sarlis Chief Medical Officer and SVP 14 de Março de 2019 A 0 0 $0
Gregory M Torre CRO and SVP 13 de Março de 2018 A 0 0 $0
Amy B Tata Principlw Acctg Officer & Cont 15 de Março de 2011 A 14.065 0 0 $0
Ramani Varanasi VP Business Development 15 de Março de 2011 A 41.083 0 0 $0
Anastasia Khvorova Chief Science Officer 15 de Março de 2011 A 60.559 0 0 $0
Pamela Pavco VP of Pharmaceutical Devlpmt 15 de Março de 2011 A 44.940 0 0 $0
Konstantinos Andrikopoulos VP, Legal 15 de Abril de 2010 A 5.750 0 0 $0
Dmitry Samarsky VP, Technology Development 31 de Março de 2010 S 0 0 0 $0
Katherine Bach Kalin Conselheiro 7 de Janeiro de 2026 A 154.400 1 0 $100.806
John Varian Conselheiro 7 de Janeiro de 2026 A 72.900 0 0 $0
Jane Wasman Conselheiro 7 de Janeiro de 2026 A 92.900 0 0 $0
David A Scheinberg Conselheiro 7 de Janeiro de 2026 A 73.082 0 0 $0
Robert L Van Nostrand Conselheiro 7 de Janeiro de 2026 A 82.900 0 0 $0
Stephen F Ghiglieri Conselheiro 14 de Março de 2019 A 0 0 $0
Fabio Lopez Conselheiro 12 de Junho de 2018 A 0 0 $0
Irving M. Einhorn 10 de Outubro de 2017 A 34.690 0 0 $0
William Ashton 10 de Outubro de 2017 A 38.154 0 0 $0
Richard Chin 10 de Outubro de 2017 A 31.339 0 0 $0
Rudolph Nisi 10 de Outubro de 2017 A 42.918 0 0 $0
Sanford Hillsberg 10 de Outubro de 2017 A 56.950 0 0 $0
Mary Ann Gray 10 de Outubro de 2017 A 39.167 0 0 $0
Stephen S Galliker 10 de Outubro de 2017 A 36.039 0 0 $0
Thomas J Knapp 6 de Fevereiro de 2017 A 0 0 $0
Bijan Nejadnik 17 de Janeiro de 2017 A 0 0 $0
Ryan Dunlap 1 de Junho de 2016 M 18.702 0 0 $0
Mark W. Schwartz 18 de Dezembro de 2015 A 415.972 0 0 $0
Steven A Kriegsman 19 de Junho de 2015 A 5.000 0 0 $0
Margaret Kivinski 16 de Janeiro de 2015 A 0 0 $0
Brian L Hamilton 30 de Junho de 2014 J 2.461 0 0 $0
Mark J Ahn 30 de Junho de 2014 A 116.225 0 0 $0
Rosemary Mazanet 29 de Janeiro de 2013 A 0 0 $0
CYTRX CORP 29 de Dezembro de 2010 S 0 0 0 $0
Tod Woolf 15 de Janeiro de 2009 A 0 0 $0

Executivos de declarações SEC Formulário 3/4/5; líquido = apenas P/V de mercado aberto

Ativistas e proprietários de 5%+ 2 participações

Investidores que apresentaram o Schedule 13D da SEC — propriedade benéfica acima de 5% com a intenção de influenciar o emissor (participações ativistas, campanhas no conselho, M&A). Cada linha mostra o estado mais recente conhecido da posição desse declarante.

Declarante Declarado Participação Status Propósito Declaração
Equilibria Capital Management Limited (2), EQC Private Markets SAC Fund II Ltd — EQC Biotech Sely S Fund (2), EQC Private Markets SAC Fund Ltd — EQC Biotech Sely I Fund (2), EQC Private Markets SAC Fund Ltd — EQC Biotech Sely II Fund (2), EQC Private Markets II SAC Fund Ltd — EQC Biotech Sely III Fund (2), Varibobi Financial Holdings Ltd. (2), Daniel Tafur (2), Fabio López (2) ×4 declarações 10 de Outubro de 2018 Declaração inicial SEC
Angelos M. Stergiou, M.D., Sc.D. h.c. 8 de Janeiro de 2018 Declaração inicial M&A / venda SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Participação em ETFs Detido por 29 ETFs

O peso reflete apenas participações diretas em ações (N-PORT); fundos alavancados ou baseados em derivativos podem deter exposição adicional a swaps não mostrada.

Fundo Peso Unidades Em Fonte
DWAS · Invesco Exchange-Traded Fund Trust … 0,77% 288.499 SH 8 de Agosto de 2026 Diário
IWC · iShares Trust 0,50% 640.415 SH 8 de Agosto de 2026 Diário
LABU · Direxion Shares ETF Trust 0,26% 268.465 NS 30 de Abril de 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0,23% 316.525 SH 8 de Agosto de 2026 Diário
ICOP · iShares Trust 0,22% 126.361 SH 8 de Agosto de 2026 Diário
CANC · Tema ETF Trust 0,22% 40.702 NS 31 de Maio de 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0,16% 202.339 SH 8 de Agosto de 2026 Diário
IWO · iShares Trust 0,14% 1.712.069 SH 8 de Agosto de 2026 Diário
VTWO · VANGUARD SCOTTSDALE FUNDS 0,08% 1.086.285 SH 8 de Agosto de 2026 Diário
IWM · iShares Trust 0,07% 4.828.431 SH 8 de Agosto de 2026 Diário
ISCG · iShares Trust 0,07% 57.511 SH 8 de Agosto de 2026 Diário
GSSC · Goldman Sachs ETF Trust 0,05% 51.293 NS 31 de Maio de 2026 N-PORT
PICK · iShares, Inc. 0,04% 122.564 SH 8 de Agosto de 2026 Diário
ITWO · ProShares Trust 0,04% 8.088 NS 31 de Maio de 2026 N-PORT
VHT · VANGUARD WORLD FUND 0,04% 540.244 SH 8 de Agosto de 2026 Diário
ISCF · iShares Trust 0,04% 30.200 SH 8 de Agosto de 2026 Diário
ISCB · iShares Trust 0,03% 8.283 SH 8 de Agosto de 2026 Diário
VXF · VANGUARD INDEX FUNDS 0,03% 2.134.285 SH 8 de Agosto de 2026 Diário
WSML · iShares Trust 0,03% 16.889 SH 8 de Agosto de 2026 Diário
RSSL · Global X Funds 0,03% 74.459 NS 30 de Abril de 2026 N-PORT
UWM · ProShares Trust 0,02% 6.326 NS 31 de Maio de 2026 N-PORT
URTY · ProShares Trust 0,02% 6.397 NS 31 de Maio de 2026 N-PORT
HDG · ProShares Trust 0,01% 161 NS 31 de Maio de 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0,01% 64.480 NS 31 de Maio de 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,00% 3.554 NS 31 de Maio de 2026 N-PORT
ITOT · iShares Trust 0,00% 273.812 SH 8 de Agosto de 2026 Diário
IWV · iShares Trust 0,00% 43.929 SH 8 de Agosto de 2026 Diário
VTI · VANGUARD INDEX FUNDS 0,00% 5.908.560 SH 8 de Agosto de 2026 Diário
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 15.706 SH 8 de Agosto de 2026 Diário