GPCR — الملاك المؤسسيون (13F)
المؤسسات التي تبلغ عن حيازتها لهذا السهم في نموذج SEC 13F ربع السنوي الخاص بها. المراكز الطويلة فقط؛ قد يظهر مقدم واحد مرتين لأرجل خيارات منفصلة. الأرجل الكبيرة المتعاكسة من خيارات البيع/الشراء تعكس عادةً صناعة السوق أو المخزون المتحوط، وليس القناعة الاتجاهية.
| مؤسسة | القيمة | الأسهم | % من 13F المتتبعة | النوع |
|---|---|---|---|---|
| FMR LLC | $419179123 | 7810306 | 11,69% | الأسهم |
| WELLINGTON MANAGEMENT GROUP LLP | $396054169 | 7379433 | 11,05% | الأسهم |
| Avoro Capital Advisors LLC | $351836637 | 6555555 | 9,81% | الأسهم |
| JANUS HENDERSON GROUP PLC | $258260143 | 5354981 | 7,20% | الأسهم |
| Deep Track Capital, LP | $254399664 | 4740072 | 7,10% | الأسهم |
| BVF INC/IL | $180697390 | 3366823 | 5,04% | الأسهم |
| MORGAN STANLEY | $150632372 | 2806640 | 4,20% | الأسهم |
| ORBIMED ADVISORS LLC | $118578498 | 2209400 | 3,31% | الأسهم |
| PRINCIPAL FINANCIAL GROUP INC | $94070254 | 1752753 | 2,62% | الأسهم |
| AMERICAN CENTURY COMPANIES INC | $90282956 | 1682179 | 2,52% | الأسهم |
| RTW INVESTMENTS, LP | $86274901 | 1607507 | 2,41% | الأسهم |
| Driehaus Capital Management LLC | $83361264 | 1553219 | 2,33% | الأسهم |
| BAKER BROS. ADVISORS LP | $76883831 | 1432529 | 2,14% | الأسهم |
| Casdin Capital, LLC | $63062250 | 1175000 | 1,76% | الأسهم |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $58285620 | 1086000 | 1,63% | الأسهم |
| CAPITOLIS LIQUID GLOBAL MARKETS LLC | $55875837 | 1041100 | 1,56% | الأسهم |
| Siren, L.L.C. | $46852139 | 872967 | 1,31% | الأسهم |
| Pacific Heights Asset Management LLC | $42936000 | 800000 | 1,20% | الأسهم |
| Rock Springs Capital Management LP | $34365813 | 640317 | 0,96% | الأسهم |
| Aberdeen Group plc | $34344238 | 639915 | 0,96% | الأسهم |
| FRANKLIN RESOURCES INC | $31066308 | 578839 | 0,87% | الأسهم |
| BANK OF AMERICA CORP /DE/ | $30238858 | 563422 | 0,84% | الأسهم |
| ALLIANCEBERNSTEIN L.P. | $29484326 | 611708 | 0,82% | الأسهم |
| BlackRock, Inc. | $27433368 | 511149 | 0,77% | الأسهم |
| Logos Global Management LP | $26835000 | 500000 | 0,75% | الأسهم |
| Parkman Healthcare Partners LLC | $26065426 | 485661 | 0,73% | الأسهم |
| Davern Capital Partners, LP | $23939987 | 446059 | 0,67% | الأسهم |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $22476996 | 418800 | 0,63% | الأسهم |
| UBS Group AG | $20340179 | 378986 | 0,57% | الأسهم |
| DEUTSCHE BANK AG\ | $17811302 | 331867 | 0,50% | الأسهم |
| NEXTBio Capital Management LP | $16771660 | 312496 | 0,47% | الأسهم |
| Catalio Capital Management, LP | $14842438 | 276550 | 0,41% | الأسهم |
| MARSHALL WACE, LLP | $14361663 | 267592 | 0,40% | الأسهم |
| HSG Holding Ltd | $14279548 | 266062 | 0,40% | الأسهم |
| SEB Asset Management AB | $13151433 | 245043 | 0,37% | الأسهم |
| GOLDMAN SACHS GROUP INC | $13030539 | 242790 | 0,36% | الأسهم |
| AMERIPRISE FINANCIAL INC | $12371685 | 230514 | 0,35% | الأسهم |
| NATIONAL BANK OF CANADA /FI/ | $11581986 | 215800 | 0,32% | الأسهم |
| TWO SIGMA INVESTMENTS, LP | $10957053 | 204156 | 0,31% | الأسهم |
| Eversept Partners, LP | $10535528 | 196302 | 0,29% | الأسهم |
| Schonfeld Strategic Advisors LLC | $10234062 | 190685 | 0,29% | الأسهم |
| Woodline Partners LP | $8254875 | 153808 | 0,23% | الأسهم |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $8218000 | 153119 | 0,23% | الأسهم |
| ArrowMark Colorado Holdings LLC | $8081575 | 150579 | 0,23% | الأسهم |
| Susquehanna Portfolio Strategies, LLC | $7994039 | 148948 | 0,22% | الأسهم |
| CenterBook Partners LP | $7944770 | 148030 | 0,22% | الأسهم |
| Rhenman & Partners Asset Management AB | $7787517 | 145100 | 0,22% | الأسهم |
| GOLDMAN SACHS GROUP INC | $7782150 | 145000 | 0,22% | عقد خيار الشراء |
| B Group, Inc. | $7513800 | 140000 | 0,21% | الأسهم |
| HighVista Strategies LLC | $7019177 | 130784 | 0,20% | الأسهم |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $6745728 | 125689 | 0,19% | الأسهم |
| Squarepoint Ops LLC | $6739610 | 125575 | 0,19% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6566202 | 122344 | 0,18% | الأسهم |
| D. E. Shaw & Co., Inc. | $6188151 | 115300 | 0,17% | الأسهم |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $6027141 | 112300 | 0,17% | الأسهم |
| Soleus Capital Management, L.P. | $5742690 | 107000 | 0,16% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5302596 | 98800 | 0,15% | عقد خيار الشراء |
| Avidity Partners Management LP | $5259660 | 98000 | 0,15% | الأسهم |
| GEODE CAPITAL MANAGEMENT, LLC | $5215811 | 97183 | 0,15% | الأسهم |
| Qube Research & Technologies Ltd | $5012939 | 93403 | 0,14% | الأسهم |
| PEREGRINE CAPITAL MANAGEMENT LLC | $4949930 | 92229 | 0,14% | الأسهم |
| PFM Health Sciences, LP | $4913489 | 91550 | 0,14% | الأسهم |
| PLATINUM INVESTMENT MANAGEMENT LTD | $4849782 | 90363 | 0,14% | الأسهم |
| MILLENNIUM MANAGEMENT LLC | $4807115 | 89568 | 0,13% | الأسهم |
| ExodusPoint Capital Management, LP | $4200536 | 78266 | 0,12% | الأسهم |
| Boxer Capital Management, LLC | $4025250 | 75000 | 0,11% | الأسهم |
| Cormorant Asset Management, LP | $4025250 | 75000 | 0,11% | الأسهم |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $4025250 | 75000 | 0,11% | الأسهم |
| CITADEL ADVISORS LLC | $4014516 | 74800 | 0,11% | عقد خيار الشراء |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3869607 | 72100 | 0,11% | عقد خيار البيع |
| ALPS ADVISORS INC | $3855277 | 71833 | 0,11% | الأسهم |
| TD Asset Management Inc | $3701191 | 68962 | 0,10% | الأسهم |
| Point72 Europe (London) LLP | $3267516 | 116697 | 0,09% | الأسهم |
| Brevan Howard Capital Management LP | $3258144 | 60336 | 0,09% | الأسهم |
| Burkehill Global Management, LP | $3220200 | 60000 | 0,09% | الأسهم |
| RAYMOND JAMES FINANCIAL INC | $3185689 | 59357 | 0,09% | الأسهم |
| JANE STREET GROUP, LLC | $3026988 | 56400 | 0,08% | عقد خيار الشراء |
| CITADEL ADVISORS LLC | $2908914 | 54200 | 0,08% | عقد خيار البيع |
| TUDOR INVESTMENT CORP ET AL | $2879718 | 53656 | 0,08% | الأسهم |
| ANTIPODES PARTNERS Ltd | $2751232 | 51262 | 0,08% | الأسهم |
| SCOGGIN MANAGEMENT LP | $2683500 | 50000 | 0,07% | عقد خيار الشراء |
| Buckland Partners Management Co LLC | $2683500 | 50000 | 0,07% | الأسهم |
| SEVEN GRAND MANAGERS, LLC | $2683500 | 50000 | 0,07% | الأسهم |
| DAFNA Capital Management LLC | $2495655 | 46500 | 0,07% | الأسهم |
| Mariner, LLC | $2484116 | 46285 | 0,07% | الأسهم |
| OSAIC HOLDINGS, INC. | $2403594 | 44786 | 0,07% | الأسهم |
| STATE STREET CORP | $2395238 | 44629 | 0,07% | الأسهم |
| VOYA INVESTMENT MANAGEMENT LLC | $2383485 | 44410 | 0,07% | الأسهم |
| BANQUE PICTET & CIE SA | $2325628 | 43332 | 0,06% | الأسهم |
| Jump Financial, LLC | $2289455 | 42658 | 0,06% | الأسهم |
| BANK OF MONTREAL /CAN/ | $2284733 | 42570 | 0,06% | الأسهم |
| Cinctive Capital Management LP | $2193869 | 40877 | 0,06% | الأسهم |
| Jefferies Financial Group Inc. | $2180344 | 40625 | 0,06% | الأسهم |
| Jones Hill Capital LP | $2177231 | 40567 | 0,06% | الأسهم |
| STEMPOINT CAPITAL LP | $2049013 | 38178 | 0,06% | الأسهم |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2045256 | 38108 | 0,06% | الأسهم |
| CAPITAL FUND MANAGEMENT S.A. | $2000871 | 37281 | 0,06% | الأسهم |
| PSquared Asset Management AG | $1996524 | 37200 | 0,06% | الأسهم |
| FLAX POND CAPITAL, LLC | $1932120 | 36000 | 0,05% | الأسهم |
| TrueMark Investments, LLC | $1803312 | 33600 | 0,05% | الأسهم |
| NOMURA ASSET MANAGEMENT CO LTD | $1759839 | 32790 | 0,05% | الأسهم |
| DCF Advisers, LLC | $1722807 | 32100 | 0,05% | الأسهم |
| EXCHANGE TRADED CONCEPTS, LLC | $1651587 | 30773 | 0,05% | الأسهم |
| SPHERA FUNDS MANAGEMENT LTD. | $1534962 | 28600 | 0,04% | الأسهم |
| Verition Fund Management LLC | $1530615 | 28519 | 0,04% | الأسهم |
| Y-Intercept (Hong Kong) Ltd | $1479843 | 27573 | 0,04% | الأسهم |
| Seven Fleet Capital Management LP | $1441572 | 26800 | 0,04% | الأسهم |
| MML INVESTORS SERVICES, LLC | $1374006 | 25601 | 0,04% | الأسهم |
| Birchview Capital, LP | $1288080 | 24000 | 0,04% | الأسهم |
| NOMURA HOLDINGS INC | $1227594 | 22873 | 0,03% | الأسهم |
| BARCLAYS PLC | $1085798 | 20231 | 0,03% | الأسهم |
| BNP PARIBAS FINANCIAL MARKETS | $954306 | 17781 | 0,03% | الأسهم |
| ADAR1 Capital Management, LLC | $939225 | 17500 | 0,03% | الأسهم |
| STIFEL FINANCIAL CORP | $806771 | 15032 | 0,02% | الأسهم |
| LPL Financial LLC | $769252 | 14333 | 0,02% | الأسهم |
| WEXFORD CAPITAL LP | $735762 | 13709 | 0,02% | الأسهم |
| SEI INVESTMENTS CO | $734422 | 13684 | 0,02% | الأسهم |
| BRANDYWINE MANAGERS, LLC | $716870 | 13357 | 0,02% | الأسهم |
| Gladstone Institutional Advisory LLC | $712469 | 13275 | 0,02% | الأسهم |
| Fulcrum Asset Management LLP | $684996 | 13252 | 0,02% | الأسهم |
| China Universal Asset Management Co., Ltd. | $665991 | 12409 | 0,02% | الأسهم |
| ENVESTNET ASSET MANAGEMENT INC | $621241 | 11575 | 0,02% | الأسهم |
| Verdad Advisers, LP | $608349 | 11335 | 0,02% | الأسهم |
| DNB Asset Management AS | $578509 | 10779 | 0,02% | الأسهم |
| FOX RUN MANAGEMENT, L.L.C. | $578348 | 10776 | 0,02% | الأسهم |
| WELLS FARGO & COMPANY/MN | $558033 | 10398 | 0,02% | الأسهم |
| HighTower Advisors, LLC | $538253 | 10029 | 0,02% | الأسهم |
| Quinn Opportunity Partners LLC | $536700 | 10000 | 0,01% | الأسهم |
| SmartHarvest Portfolios, LLC | $532836 | 9928 | 0,01% | الأسهم |
| CITIGROUP INC | $519526 | 9680 | 0,01% | الأسهم |
| Gilbert & Cook, Inc. | $491993 | 9167 | 0,01% | الأسهم |
| IMC-Chicago, LLC | $462528 | 8618 | 0,01% | الأسهم |
| Cubist Systematic Strategies, LLC | $456736 | 16312 | 0,01% | الأسهم |
| JANE STREET GROUP, LLC | $450828 | 8400 | 0,01% | عقد خيار البيع |
| SIMPLEX TRADING, LLC | $422436 | 7871 | 0,01% | الأسهم |
| Clearstead Advisors, LLC | $420021 | 7826 | 0,01% | الأسهم |
| Quadcap Wealth Management, LLC | $409769 | 7635 | 0,01% | الأسهم |
| Virtus Investment Advisers, LLC | $409073 | 7622 | 0,01% | الأسهم |
| Allianz Asset Management GmbH | $407892 | 7600 | 0,01% | الأسهم |
| MISSION WEALTH MANAGEMENT, LP | $406980 | 7583 | 0,01% | الأسهم |
| Vestmark Advisory Solutions, Inc. | $404350 | 7534 | 0,01% | الأسهم |
| Parallel Advisors, LLC | $394582 | 7352 | 0,01% | الأسهم |
| Cetera Investment Advisers | $356261 | 6638 | 0,01% | الأسهم |
| EntryPoint Capital, LLC | $329319 | 6136 | 0,01% | الأسهم |
| Good Life Advisors, LLC | $311100 | 15000 | 0,01% | الأسهم |
| Mirae Asset Global Investments Co., Ltd. | $274093 | 5107 | 0,01% | الأسهم |
| NORTHERN TRUST CORP | $272644 | 5080 | 0,01% | الأسهم |
| Concurrent Investment Advisors, LLC | $268350 | 5000 | 0,01% | الأسهم |
| Bellevue Group AG | $255577 | 4762 | 0,01% | الأسهم |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $249297 | 4645 | 0,01% | الأسهم |
| Independent Advisor Alliance | $243823 | 4543 | 0,01% | الأسهم |
| SECTORAL ASSET MANAGEMENT INC | $232123 | 4325 | 0,01% | الأسهم |
| PEAK6 LLC | $222999 | 4155 | 0,01% | الأسهم |
| Walleye Trading LLC | $220745 | 4113 | 0,01% | الأسهم |
| Prospera Financial Services Inc | $220042 | 4100 | 0,01% | الأسهم |
| E. Ohman J:or Asset Management AB | $217768 | 4518 | 0,01% | الأسهم |
| GABELLI FUNDS LLC | $217364 | 4050 | 0,01% | الأسهم |
| TUDOR INVESTMENT CORP ET AL | $214680 | 4000 | 0,01% | عقد خيار الشراء |
| Invesco Ltd. | $212050 | 3951 | 0,01% | الأسهم |
| JPMORGAN CHASE & CO | $205933 | 3984 | 0,01% | الأسهم |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | $187845 | 3500 | 0,01% | الأسهم |
| State of Wyoming | $166431 | 3101 | 0,00% | الأسهم |
| PNC Financial Services Group, Inc. | $149310 | 2782 | 0,00% | الأسهم |
| ASSETMARK, INC | $146304 | 2726 | 0,00% | الأسهم |
| NATIXIS | $135095 | 2482 | 0,00% | الأسهم |
| Rockefeller Capital Management L.P. | $134926 | 2514 | 0,00% | الأسهم |
| Sterling Capital Management LLC | $109755 | 2045 | 0,00% | الأسهم |
| Farther Finance Advisors, LLC | $88878 | 1656 | 0,00% | الأسهم |
| GF FUND MANAGEMENT CO. LTD. | $88609 | 1651 | 0,00% | الأسهم |
| Federation des caisses Desjardins du Quebec | $80490 | 1500 | 0,00% | الأسهم |
| Steward Partners Investment Advisory, LLC | $75138 | 1400 | 0,00% | الأسهم |
| Tower Research Capital LLC (TRC) | $48142 | 897 | 0,00% | الأسهم |
| IFP Advisors, Inc | $46049 | 858 | 0,00% | الأسهم |
| PRICE T ROWE ASSOCIATES INC /MD/ | $45380 | 845532 | 0,00% | الأسهم |
| GAMMA Investing LLC | $44868 | 836 | 0,00% | الأسهم |
| ROYAL BANK OF CANADA | $30000 | 550 | 0,00% | الأسهم |
| WOLFF WIESE MAGANA LLC | $21468 | 400 | 0,00% | الأسهم |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $20663 | 385 | 0,00% | الأسهم |
| North Star Investment Management Corp. | $17711 | 330 | 0,00% | الأسهم |
| Quarry LP | $13149 | 245 | 0,00% | الأسهم |
| Godfrey Financial Associates, Inc. | $13149 | 245 | 0,00% | الأسهم |
| JONES FINANCIAL COMPANIES LLLP | $8699 | 175 | 0,00% | الأسهم |
| Dynamic Wealth Strategies, LLC | $8051 | 150 | 0,00% | الأسهم |
| CWM, LLC | $6025 | 125 | 0,00% | الأسهم |
| Key Financial Inc | $5367 | 100 | 0,00% | الأسهم |
| SHP Wealth Management | $5367 | 100 | 0,00% | الأسهم |
| SIGNATUREFD, LLC | $5367 | 100 | 0,00% | الأسهم |
| HUNTINGTON NATIONAL BANK | $4240 | 79 | 0,00% | الأسهم |
| Rakuten Securities, Inc. | $3220 | 60 | 0,00% | الأسهم |
| Arax Advisory Partners | $1825 | 34 | 0,00% | الأسهم |
| GSA CAPITAL PARTNERS LLP | $1538 | 28665 | 0,00% | الأسهم |
| Transamerica Financial Advisors, LLC | $1180 | 22 | 0,00% | الأسهم |
| Ares Financial Consulting, LLC | $1073 | 20 | 0,00% | الأسهم |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | $928 | 17297 | 0,00% | الأسهم |
| Smartleaf Asset Management LLC | $879 | 17 | 0,00% | الأسهم |
| Janney Capital Management LLC | $592 | 8513 | 0,00% | الأسهم |
| Caitong International Asset Management Co., Ltd | $537 | 10 | 0,00% | الأسهم |
| Cullen/Frost Bankers, Inc. | $429 | 8 | 0,00% | الأسهم |
| Larson Financial Group LLC | $322 | 6 | 0,00% | الأسهم |
| Janney Montgomery Scott LLC | $288 | 5364 | 0,00% | الأسهم |
| SG Americas Securities, LLC | $130 | 2427 | 0,00% | الأسهم |
| Point72 Asia (Singapore) Pte. Ltd. | $28 | 1 | 0,00% | الأسهم |
| Capital Analysts, LLC | $1 | 18 | 0,00% | الأسهم |
| BESSEMER GROUP INC | $1 | 22 | 0,00% | الأسهم |