UPB — Institutionelle Eigentümer (13F)
Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.
| Institution | Wert | Aktien | % der verfolgten 13F | Typ |
|---|---|---|---|---|
| VANGUARD GROUP INC | $64.846.119 | 2.388.439 | 15,74% | Aktien |
| FMR LLC | $56.487.247 | 8.162.897 | 13,71% | Aktien |
| ORBIMED ADVISORS LLC | $39.399.636 | 5.693.589 | 9,56% | Aktien |
| NORGES BANK | $26.078.843 | 3.768.619 | 6,33% | Aktien |
| BlackRock, Inc. | $25.973.237 | 3.753.358 | 6,30% | Aktien |
| Decheng Capital LLC | $18.856.087 | 2.724.868 | 4,58% | Aktien |
| ENAVATE SCIENCES GP, LLC | $17.021.145 | 2.459.703 | 4,13% | Aktien |
| VANGUARD CAPITAL MANAGEMENT LLC | $12.986.999 | 1.876.734 | 3,15% | Aktien |
| MILLENNIUM MANAGEMENT LLC | $7.914.923 | 1.143.775 | 1,92% | Aktien |
| D. E. Shaw & Co., Inc. | $7.169.425 | 1.036.044 | 1,74% | Aktien |
| JPMORGAN CHASE & CO | $7.013.464 | 1.012.044 | 1,70% | Aktien |
| Qube Research & Technologies Ltd | $6.771.220 | 978.500 | 1,64% | Aktien |
| Parkman Healthcare Partners LLC | $6.471.909 | 935.247 | 1,57% | Aktien |
| GEODE CAPITAL MANAGEMENT, LLC | $6.445.888 | 931.261 | 1,56% | Aktien |
| SEB Asset Management AB | $6.079.022 | 878.473 | 1,48% | Aktien |
| Woodline Partners LP | $5.753.849 | 831.481 | 1,40% | Aktien |
| STATE STREET CORP | $5.302.955 | 766.323 | 1,29% | Aktien |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $4.931.656 | 712.667 | 1,20% | Aktien |
| Y-Intercept (Hong Kong) Ltd | $4.799.401 | 693.555 | 1,16% | Aktien |
| Bain Capital Life Sciences Investors, LLC | $4.158.567 | 600.949 | 1,01% | Aktien |
| AQR CAPITAL MANAGEMENT LLC | $3.770.493 | 544.869 | 0,92% | Aktien |
| MORGAN STANLEY | $3.630.453 | 524.632 | 0,88% | Aktien |
| BNP PARIBAS FINANCIAL MARKETS | $3.539.898 | 511.546 | 0,86% | Aktien |
| Walleye Capital LLC | $3.449.551 | 498.490 | 0,84% | Aktien |
| Trexquant Investment LP | $3.227.696 | 466.430 | 0,78% | Aktien |
| Point72 Asset Management, L.P. | $3.134.836 | 453.011 | 0,76% | Aktien |
| BANK OF AMERICA CORP /DE/ | $2.710.993 | 391.762 | 0,66% | Aktien |
| DIMENSIONAL FUND ADVISORS LP | $2.640.811 | 381.613 | 0,64% | Aktien |
| Altshuler Shaham Ltd | $2.630.022 | 380.061 | 0,64% | Aktien |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $2.475.672 | 357.756 | 0,60% | Aktien |
| SAMSARA BIOCAPITAL, LLC | $2.447.722 | 353.717 | 0,59% | Aktien |
| Propel Bio Management, LLC | $2.424.692 | 350.389 | 0,59% | Aktien |
| WELLINGTON MANAGEMENT GROUP LLP | $2.369.083 | 342.353 | 0,57% | Aktien |
| NORTHERN TRUST CORP | $2.057.634 | 297.346 | 0,50% | Aktien |
| Squarepoint Ops LLC | $2.013.056 | 290.904 | 0,49% | Aktien |
| Voleon Capital Management LP | $1.973.819 | 285.234 | 0,48% | Aktien |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1.816.196 | 262.456 | 0,44% | Aktien |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1.751.397 | 253.092 | 0,43% | Aktien |
| GOLDMAN SACHS GROUP INC | $1.708.666 | 246.917 | 0,41% | Aktien |
| XTX Topco Ltd | $1.677.034 | 242.346 | 0,41% | Aktien |
| DEUTSCHE BANK AG\ | $1.670.814 | 241.447 | 0,41% | Aktien |
| VANGUARD FIDUCIARY TRUST CO | $1.658.143 | 239.616 | 0,40% | Aktien |
| UBS Group AG | $1.624.221 | 234.714 | 0,39% | Aktien |
| Schonfeld Strategic Advisors LLC | $1.562.258 | 225.760 | 0,38% | Aktien |
| Jump Financial, LLC | $1.544.703 | 223.223 | 0,37% | Aktien |
| SPHERA FUNDS MANAGEMENT LTD. | $1.520.324 | 219.700 | 0,37% | Aktien |
| Boxer Capital Management, LLC | $1.038.000 | 150.000 | 0,25% | Aktien |
| RENAISSANCE TECHNOLOGIES LLC | $908.596 | 131.300 | 0,22% | Aktien |
| EntryPoint Capital, LLC | $895.766 | 129.446 | 0,22% | Aktien |
| ALGERT GLOBAL LLC | $820.920 | 118.630 | 0,20% | Aktien |
| Bank of New York Mellon Corp | $593.369 | 85.747 | 0,14% | Aktien |
| Nuveen, LLC | $586.608 | 84.770 | 0,14% | Aktien |
| AMERICAN CENTURY COMPANIES INC | $541.102 | 78.194 | 0,13% | Aktien |
| Man Group plc | $510.855 | 73.823 | 0,12% | Aktien |
| ALLIANCEBERNSTEIN L.P. | $465.120 | 51.680 | 0,11% | Aktien |
| Simplify Asset Management Inc. | $429.822 | 62.113 | 0,10% | Aktien |
| ALPS ADVISORS INC | $382.178 | 55.228 | 0,09% | Aktien |
| Quantinno Capital Management LP | $379.479 | 54.838 | 0,09% | Aktien |
| Virtus Investment Advisers, LLC | $371.175 | 53.638 | 0,09% | Aktien |
| Invesco Ltd. | $369.508 | 53.397 | 0,09% | Aktien |
| Brevan Howard Capital Management LP | $348.553 | 50.369 | 0,08% | Aktien |
| Swiss National Bank | $332.852 | 48.100 | 0,08% | Aktien |
| Russell Investments Group, Ltd. | $329.000 | 47.543 | 0,08% | Aktien |
| Allspring Global Investments Holdings, LLC | $298.819 | 43.182 | 0,07% | Aktien |
| RHUMBLINE ADVISERS | $293.288 | 42.384 | 0,07% | Aktien |
| TWO SIGMA INVESTMENTS, LP | $292.889 | 42.325 | 0,07% | Aktien |
| ExodusPoint Capital Management, LP | $284.031 | 41.045 | 0,07% | Aktien |
| CITIGROUP INC | $279.145 | 40.339 | 0,07% | Aktien |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $267.347 | 38.634 | 0,06% | Aktien |
| Stonepine Capital Management, LLC | $231.349 | 33.432 | 0,06% | Aktien |
| Mariner, LLC | $229.337 | 33.141 | 0,06% | Aktien |
| WELLS FARGO & COMPANY/MN | $204.119 | 29.497 | 0,05% | Aktien |
| BARCLAYS PLC | $202.120 | 29.208 | 0,05% | Aktien |
| Creative Planning | $197.102 | 28.483 | 0,05% | Aktien |
| Quantbot Technologies LP | $194.992 | 28.178 | 0,05% | Aktien |
| AXQ CAPITAL, LP | $187.311 | 27.068 | 0,05% | Aktien |
| nVerses Capital, LLC | $166.280 | 24.029 | 0,04% | Aktien |
| DNB Asset Management AS | $163.312 | 23.600 | 0,04% | Aktien |
| VANGUARD ASSET MANAGEMENT, Ltd | $157.250 | 22.724 | 0,04% | Aktien |
| Graham Capital Management, L.P. | $155.755 | 22.508 | 0,04% | Aktien |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $154.904 | 22.385 | 0,04% | Aktien |
| Verdad Advisers, LP | $150.925 | 21.810 | 0,04% | Aktien |
| MetLife Investment Management, LLC | $144.296 | 20.852 | 0,04% | Aktien |
| SEI INVESTMENTS CO | $138.580 | 20.026 | 0,03% | Aktien |
| WINTON GROUP Ltd | $137.016 | 19.800 | 0,03% | Aktien |
| IEQ CAPITAL, LLC | $135.182 | 19.535 | 0,03% | Aktien |
| DIADEMA PARTNERS LP | $132.124 | 19.093 | 0,03% | Aktien |
| Shay Capital LLC | $124.560 | 18.000 | 0,03% | Aktien |
| Quadrature Capital Ltd | $124.477 | 17.988 | 0,03% | Aktien |
| Entropy Technologies, LP | $121.391 | 17.542 | 0,03% | Aktien |
| STATE OF WISCONSIN INVESTMENT BOARD | $118.090 | 17.065 | 0,03% | Aktien |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $112.222 | 16.217 | 0,03% | Aktien |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $108.886 | 15.735 | 0,03% | Aktien |
| JANE STREET GROUP, LLC | $107.910 | 15.594 | 0,03% | Aktien |
| CITADEL ADVISORS LLC | $103.800 | 15.000 | 0,03% | Kaufoption |
| MERCER GLOBAL ADVISORS INC /ADV | $92.396 | 13.352 | 0,02% | Aktien |
| Vanguard Global Advisers, LLC | $90.368 | 13.059 | 0,02% | Aktien |
| Legal & General Group Plc | $86.922 | 12.561 | 0,02% | Aktien |
| Engineers Gate Manager LP | $86.438 | 12.491 | 0,02% | Aktien |
| STRS OHIO | $83.040 | 12.000 | 0,02% | Aktien |
| JANE STREET GROUP, LLC | $82.348 | 11.900 | 0,02% | Kaufoption |
| CANADA PENSION PLAN INVESTMENT BOARD | $79.580 | 11.500 | 0,02% | Aktien |
| HSBC HOLDINGS PLC | $77.602 | 10.793 | 0,02% | Aktien |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $75.428 | 10.017 | 0,02% | Aktien |
| PRELUDE CAPITAL MANAGEMENT, LLC | $73.006 | 10.550 | 0,02% | Aktien |
| AMERIPRISE FINANCIAL INC | $72.570 | 10.487 | 0,02% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $69.892 | 10.100 | 0,02% | Kaufoption |
| Police & Firemen's Retirement System of New Jersey | $65.436 | 9.456 | 0,02% | Aktien |
| China Universal Asset Management Co., Ltd. | $59.934 | 8.661 | 0,01% | Aktien |
| KLP KAPITALFORVALTNING AS | $40.828 | 5.900 | 0,01% | Aktien |
| NEW YORK STATE COMMON RETIREMENT FUND | $35.984 | 5.200 | 0,01% | Aktien |
| CWM, LLC | $34.947 | 3.883 | 0,01% | Aktien |
| Persistent Asset Partners Ltd | $33.597 | 4.855 | 0,01% | Aktien |
| Tower Research Capital LLC (TRC) | $33.133 | 4.788 | 0,01% | Aktien |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $32.524 | 4.700 | 0,01% | Aktien |
| NISA INVESTMENT ADVISORS, LLC | $29.604 | 4.278 | 0,01% | Aktien |
| Vanguard Investments Australia, Ltd. | $28.344 | 4.096 | 0,01% | Aktien |
| Ameritas Investment Partners, Inc. | $18.968 | 2.741 | 0,00% | Aktien |
| Mirae Asset Global Investments Co., Ltd. | $16.843 | 2.434 | 0,00% | Aktien |
| Global Retirement Partners, LLC | $12.940 | 1.870 | 0,00% | Aktien |
| Arax Advisory Partners | $12.255 | 1.771 | 0,00% | Aktien |
| GAMMA Investing LLC | $8.055 | 1.164 | 0,00% | Aktien |
| GF FUND MANAGEMENT CO. LTD. | $7.923 | 1.145 | 0,00% | Aktien |
| ROYAL BANK OF CANADA | $7.000 | 1.091 | 0,00% | Aktien |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $6.678 | 965 | 0,00% | Aktien |
| Quarry LP | $6.180 | 893 | 0,00% | Aktien |
| Allworth Financial LP | $5.384 | 778 | 0,00% | Aktien |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $5.292 | 588 | 0,00% | Aktien |
| Rockefeller Capital Management L.P. | $5.107 | 738 | 0,00% | Aktien |
| Sterling Capital Management LLC | $4.913 | 710 | 0,00% | Aktien |
| PNC Financial Services Group, Inc. | $2.678 | 387 | 0,00% | Aktien |
| Farther Finance Advisors, LLC | $2.443 | 353 | 0,00% | Aktien |
| ROTHSCHILD INVESTMENT LLC | $1.986 | 287 | 0,00% | Aktien |
| EverSource Wealth Advisors, LLC | $1.882 | 272 | 0,00% | Aktien |
| US BANCORP \DE\ | $1.827 | 264 | 0,00% | Aktien |
| IFP Advisors, Inc | $1.675 | 242 | 0,00% | Aktien |
| Torren Management, LLC | $1.458 | 162 | 0,00% | Aktien |
| ACADIAN ASSET MANAGEMENT LLC | $1.208 | 175.110 | 0,00% | Aktien |
| HRT FINANCIAL LP | $1.180 | 170.590 | 0,00% | Aktien |
| Physician Wealth Advisors, Inc. | $1.108 | 160 | 0,00% | Aktien |
| Essential Partners LLC | $1.010 | 146 | 0,00% | Aktien |
| N.E.W. Advisory Services LLC | $830 | 120 | 0,00% | Aktien |
| SJS Investment Consulting Inc. | $526 | 76 | 0,00% | Aktien |
| GSA CAPITAL PARTNERS LLP | $480 | 69.348 | 0,00% | Aktien |
| PRICE T ROWE ASSOCIATES INC /MD/ | $195 | 28.058 | 0,00% | Aktien |
| Silver Grove Financial Group, Inc. | $194 | 28 | 0,00% | Aktien |
| SG Americas Securities, LLC | $141 | 20.338 | 0,00% | Aktien |
| SIMPLEX TRADING, LLC | $138 | 20 | 0,00% | Aktien |
| OSAIC HOLDINGS, INC. | $131 | 19 | 0,00% | Aktien |
| Clearstead Advisors, LLC | $105 | 15 | 0,00% | Aktien |
| JPL Wealth Management, LLC | $97 | 14 | 0,00% | Aktien |
| Freestone Grove Partners LP | $7 | 1 | 0,00% | Aktien |
| NATIONAL BANK OF CANADA /FI/ | $7 | 1 | 0,00% | Aktien |
| Covestor Ltd | $0 | 39 | 0,00% | Aktien |