UPB Upstream Bio, Inc. - Common Stock
$7,27
Kurs · Aug 18, 2026
Fundamentaldaten per Aug 11, 2026
52W-Spanne
$6–$34
5% of range
Analystenbewertung
BUY
13 analysts
Kursziel
$38
+426% upside
P/E (TTM)
-2.7
ROE
-38.3%
Nettogewinnmarge
-5026.0%
UPB Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne
Kurs
$7.27
Marktkapitalisierung
$394M
P/E (TTM)
-2.7
EPS (TTM)
$-2.66
Umsatz (TTM)
$3M
Dividendenrendite
—
ROE
-38.3%
Verschuldungsgrad
—
52W-Spanne
$6 – $34
UPB Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen
Configure
10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends
Umsatz & Nettoergebnis
$3M
2023-12-31
→
2025-12-31
EPS
$-2.66
2023-12-31
→
2025-12-31
Freier Cashflow
$-133M
2024-12-31
→
2025-12-31
Margen
-5026.0%
Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?
Kennzahl
5-Jahres-Trend
UPB
Peer-Median
P/E (TTM)
-2.7
4.6
P/S (TTM) (K/V (TTM))
138.2
9.4
P/B (K/B)
1.2
3.7
Price / FCF (Kurs / FCF)
-3.0
—
Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC
Kennzahl
5-Jahres-Trend
UPB
Peer-Median
Operating Margin (Betriebsgewinnmarge)
-5618.8%
—
Net Profit Margin (Nettogewinnmarge)
-5026.0%
-186.4%
ROA
-34.3%
-48.0%
ROE
-38.3%
-67.6%
Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke
Kennzahl
5-Jahres-Trend
UPB
Peer-Median
Current Ratio (Liquiditätsgrad)
26.2
5.2
Quick Ratio
25.4
—
Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR
Kennzahl
5-Jahres-Trend
UPB
Peer-Median
Revenue YoY (Umsatz YoY)
20.4%
—
Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag
Kennzahl
5-Jahres-Trend
UPB
Peer-Median
UPB Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial
KAUF
13 Analysten
- Starker Kauf 2 15,4%
- Kauf 8 61,5%
- Halten 3 23,1%
- Verkauf 0 0,0%
- Starker Verkauf 0 0,0%
12-Monats-Kursziel
8 Analysten · 2026-08-13
Median
$39.50
← Unter allen Zielen
$7.27
Tief
$8.00
Hoch
$75.00
Median-Ziel
$39.50
+443,3%
Mittelwert-Ziel
$38.25
+426,1%
Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum
Durchschn. Überraschung
-0.18%
| Zeitraum | EPS Actual | EPS est. | Überraschung |
|---|---|---|---|
| 31. März 2026 | $-0.75 | $-0.78 | 0.03% |
| 31. Dezember 2025 | $-0.79 | $-0.71 | -0.08% |
| 30. September 2025 | $-0.63 | $-0.79 | 0.16% |
| 30. Juni 2025 | $-0.74 | $-0.62 | -0.12% |
| 31. März 2025 | $-0.51 | $-0.49 | -0.02% |
| 31. Dezember 2024 | $-1.59 | $-0.57 | -1.0% |
Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen
| Ticker | Marktkapitalisierung | P/E | Umsatz Vj. | Nettomarge | ROE | Bruttogewinnmarge |
|---|---|---|---|---|---|---|
| UPB | $1.47B | -10.2 | 20.4% | -5026.0% | -38.3% | — |
| FENC | $263M | -22.6 | -6.1% | -21.8% | -69.6% | — |
| LXEO | $725M | -5.3 | — | — | -51.9% | — |
| FHTX | $306M | -4.6 | 36.8% | -240.3% | 80.2% | — |
| XFOR | $364M | -2.1 | 150.0% | -1218.5% | -83.2% | — |
| PALI | $375M | -7.8 | — | — | -25.4% | — |
| RCKT | — | — | — | — | — | — |
Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow
Gewinn- und Verlustrechnung 14
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $3M | $2M | $2M | |
| R&D Expense | $137M | $63M | $32M | |
| SG&A Expense | $26M | $17M | $11M | |
| Operating Expenses | $163M | $80M | $42M | |
| Operating Income | $-160M | $-78M | $-40M | |
| Interest Income | $17M | $12M | $4M | |
| Other Non-op | $17M | $15M | $20M | |
| Income Tax | $0 | $0 | $0 | |
| Net Income | $-143M | $-63M | $-21M | |
| EPS (Basic) | $-2.66 | $-5.58 | $-12.95 | |
| EPS (Diluted) | $-2.66 | $-5.58 | $-12.95 | |
| Shares (Basic) | 53,852,752 | 13,682,326 | 2,953,756 | |
| Shares (Diluted) | 53,852,752 | 13,682,326 | 2,953,756 | |
| EBITDA | $-160M | $-78M | · |
Bilanz 22
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $102M | $326M | $26M | |
| Short-term Investments | $240M | $145M | $84M | |
| Receivables | $668.0K | $613.0K | $98.0K | |
| Prepaid Expense | $10M | $8M | $7M | |
| Other Current Assets | $727.0K | · | · | |
| Current Assets | $352M | $479M | $117M | |
| PP&E (Net) | $559.0K | $582.0K | $159.0K | |
| PP&E (Gross) | $903.0K | $738.0K | $226.0K | |
| Accum. Depreciation | $344.0K | $156.0K | $67.0K | |
| Goodwill | · | $0 | · | |
| Total Assets | $354M | $482M | $117M | |
| Accounts Payable | $3M | $4M | $2M | |
| Current Liabilities | $13M | $11M | $7M | |
| Capital Leases | $549.0K | $1M | · | |
| Total Liabilities | $14M | $12M | $9M | |
| Common Stock | $54.0K | $53.0K | $3.0K | |
| Paid-in Capital | $673M | $661M | $5M | |
| Retained Earnings | $-334M | $-191M | $-128M | |
| AOCI | $530.0K | $-25.0K | $21.0K | |
| Stockholders' Equity | $340M | $470M | $-123M | |
| Liabilities + Equity | $354M | $482M | $117M | |
| Shares Outstanding | 54,237,750 | 53,603,398 | 2,992,479 |
Cashflow 9
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| D&A | $188.0K | $89.0K | $60.0K | |
| Stock-based Comp | $10M | $6M | $3M | |
| Other Non-cash | $-352.0K | $-2M | · | |
| Operating Cash Flow | $-133M | $-59M | $-38M | |
| CapEx | $165.0K | $511.0K | $144.0K | |
| Investing Cash Flow | $-93M | $-59M | $-83M | |
| Financing Cash Flow | $2M | $419M | $130M | |
| Net Change in Cash | $-224M | $300M | $9M | |
| Free Cash Flow | $-133M | $-60M | · |
Rentabilität 5
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | -5618.8% | -3281.2% | · | |
| Net Margin | -5026.0% | -2650.0% | · | |
| EBITDA Margin | -5612.2% | -3277.4% | · | |
| ROA | -34.3% | -21.0% | · | |
| ROE | -38.3% | -40.6% | · |
Liquidität & Solvenz 2
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 26.2 | 44.6 | · | |
| Quick Ratio | 25.4 | 43.9 | · |
Effizienz 2
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | |
| Receivables Turnover | 4.5 | 6.7 | · |
Wachstumsraten 1
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | 20.4% | -0.42% | · |
Bewertung (TTM) 10
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $3M | $2M | · | |
| Net Income TTM | $-143M | $-63M | · | |
| Market Cap | $1.47B | $881M | · | |
| P/E | -10.2 | -2.9 | · | |
| P/S | 516.0 | 371.8 | · | |
| P/B | 4.3 | 1.9 | · | |
| P / Tangible Book | 4.3 | 1.9 | · | |
| P / Cash Flow | -11.0 | -14.9 | · | |
| P / FCF | -11.0 | -14.8 | · | |
| Earnings Yield | -9.8% | -33.9% | · |
Gewinn- und Verlustrechnung 14
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $773.0K | $1M | $668.0K | $683.0K | $937.0K | $566.0K | $613.0K | $607.0K | $510.0K | $640.0K | $450.0K | |
| R&D Expense | $36M | $37M | $40M | $33M | $38M | $26M | $22M | $15M | $14M | $12M | $12M | |
| SG&A Expense | $7M | $8M | $7M | $6M | $7M | $7M | $5M | $4M | $4M | $4M | $3M | |
| Operating Expenses | $43M | $45M | $47M | $39M | $45M | $33M | $27M | $20M | $18M | $16M | $15M | |
| Operating Income | $-42M | $-44M | $-46M | $-38M | $-44M | $-32M | $-26M | $-19M | $-18M | $-15M | $-14M | |
| Interest Income | $3M | $3M | $4M | $4M | $4M | $5M | $5M | $3M | $3M | $1M | $2M | |
| Other Non-op | $3M | $3M | $4M | $4M | $4M | $5M | $5M | $3M | $3M | $4M | $2M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-40M | $-41M | $-42M | $-34M | $-40M | $-27M | $-21M | $-16M | $-15M | $-11M | $-12M | |
| EPS (Basic) | $-0.73 | $-0.75 | $-0.78 | $-0.63 | $-0.74 | $-0.51 | $12.56 | $-6.96 | $-6.50 | $-4.68 | $-5.05 | |
| EPS (Diluted) | $-0.73 | $-0.75 | $-0.78 | $-0.63 | $-0.74 | $-0.51 | $12.56 | $-6.96 | $-6.50 | $-4.68 | $-5.05 | |
| Shares (Basic) | 54,567,976 | 54,332,319 | -107,466,785 | 53,930,946 | 53,770,868 | 53,617,723 | 4,654,757 | 3,023,155 | 3,008,807 | 2,995,607 | 8,952 | |
| Shares (Diluted) | 54,567,976 | 54,332,319 | -107,466,785 | 53,930,946 | 53,770,868 | 53,617,723 | 4,654,757 | 3,023,155 | 3,008,807 | 2,995,607 | 8,952 | |
| EBITDA | $-42M | $-44M | · | $-38M | $-44M | $-32M | · | $-19M | · | · | · |
Bilanz 21
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $79M | $97M | $102M | $72M | $45M | $71M | $326M | $33M | · | · | $26M | |
| Short-term Investments | $182M | $198M | $240M | $300M | $348M | $360M | $145M | $188M | · | · | $84M | |
| Receivables | $772.0K | $1M | $668.0K | $683.0K | $937.0K | $566.0K | $613.0K | $607.0K | · | · | $98.0K | |
| Prepaid Expense | $18M | $21M | $10M | $16M | $24M | $22M | $8M | $6M | · | · | $7M | |
| Other Current Assets | $1M | · | · | · | · | · | · | · | · | · | · | |
| Current Assets | $280M | $316M | $352M | $389M | $418M | $454M | $479M | $227M | · | · | $117M | |
| PP&E (Net) | $460.0K | $510.0K | $559.0K | $616.0K | $544.0K | $539.0K | $582.0K | $578.0K | · | · | $159.0K | |
| PP&E (Gross) | $903.0K | $903.0K | $903.0K | $903.0K | $785.0K | $738.0K | $738.0K | $685.0K | · | · | $226.0K | |
| Accum. Depreciation | $443.0K | $393.0K | $344.0K | $287.0K | $241.0K | $199.0K | $156.0K | $107.0K | · | · | $67.0K | |
| Total Assets | $281M | $318M | $354M | $391M | $421M | $456M | $482M | $233M | · | · | $117M | |
| Accounts Payable | $2M | $2M | $3M | $4M | $3M | $5M | $4M | $5M | · | · | $2M | |
| Current Liabilities | $10M | $14M | $13M | $12M | $11M | $10M | $11M | $11M | · | · | $7M | |
| Capital Leases | $226.0K | $390.0K | $549.0K | $703.0K | $849.0K | $992.0K | $1M | $1M | · | · | · | |
| Total Liabilities | $10M | $14M | $14M | $13M | $12M | $11M | $12M | $12M | · | · | $9M | |
| Common Stock | $54.0K | $54.0K | $54.0K | $56.0K | $54.0K | $53.0K | $53.0K | $3.0K | · | · | $3.0K | |
| Paid-in Capital | $686M | $679M | $673M | $670M | $666M | $663M | $661M | $9M | · | · | $5M | |
| Retained Earnings | $-415M | $-375M | $-334M | $-292M | $-258M | $-218M | $-191M | $-170M | · | · | $-128M | |
| AOCI | $-123.0K | $100.0K | $530.0K | $493.0K | $258.0K | $368.0K | $-25.0K | $351.0K | · | · | $21.0K | |
| Stockholders' Equity | $271M | $304M | $340M | $379M | $409M | $446M | $470M | $-160M | · | · | $-123M | |
| Liabilities + Equity | $281M | $318M | $354M | $391M | $421M | $456M | $482M | $233M | · | · | $117M | |
| Shares Outstanding | 54,771,041 | 54,419,986 | 54,237,750 | 53,999,522 | 53,798,151 | 53,640,895 | 53,603,398 | 3,025,452 | · | · | 2,992,479 |
Cashflow 8
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $50.0K | $49.0K | $57.0K | $46.0K | $42.0K | $43.0K | $49.0K | $14.0K | $13.0K | $13.0K | $14.0K | |
| Stock-based Comp | $4M | $5M | $3M | $3M | $3M | $3M | $2M | $2M | $1M | $643.0K | $711.0K | |
| Other Non-cash | · | $-12M | · | · | · | $-17M | · | · | · | · | · | |
| Operating Cash Flow | $-36M | $-48M | $-31M | $-22M | $-39M | $-41M | $-20M | $-14M | $-8M | $-18M | $-16M | |
| CapEx | · | · | $54.0K | $64.0K | · | · | $185.0K | · | · | · | $0 | |
| Investing Cash Flow | $16M | $42M | $59M | $48M | $13M | $-213M | $42M | $1M | $-117M | $14M | $-5M | |
| Financing Cash Flow | $3M | $598.0K | $1M | $760.0K | $612.0K | $-34.0K | $271M | $-2M | $141M | $9M | $-133.0K | |
| Net Change in Cash | $-17M | $-5M | $29M | $27M | $-26M | $-255M | $293M | $-14M | $16M | $6M | $-21M |
Rentabilität 5
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -5481.0% | -4218.1% | · | -5539.4% | -4732.9% | -5656.0% | · | -3112.5% | · | · | · | |
| Net Margin | -5136.1% | -3925.6% | · | -4941.1% | -4265.3% | -4818.0% | · | -2634.6% | · | · | · | |
| EBITDA Margin | -5481.0% | -4213.3% | · | -5539.4% | -4732.9% | -5648.4% | · | -3112.5% | · | · | · | |
| ROA | -11.3% | -10.5% | · | -10.8% | -19.0% | -12.0% | · | -13.7% | · | · | · | |
| ROE | -11.7% | -10.8% | · | -30.9% | -19.6% | -12.2% | · | 20.0% | · | · | · |
Liquidität & Solvenz 2
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 28.0 | 23.1 | · | 32.7 | 38.3 | 47.4 | · | 20.9 | · | · | · | |
| Quick Ratio | 26.2 | 21.6 | · | 31.3 | 36.1 | 45.1 | · | 20.3 | · | · | · |
Effizienz 2
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | · | · | · | |
| Receivables Turnover | 0.9 | 1.3 | · | 1.1 | 2.0 | 2.0 | · | 2.0 | · | · | · |
Bewertung (TTM) 9
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $3M | $3M | · | $3M | $3M | $2M | · | $2M | · | · | · | |
| Net Income TTM | $-154M | $-142M | · | $-117M | $-98M | $-69M | · | $-45M | · | · | · | |
| Market Cap | $379M | $490M | · | $1.02B | $591M | $328M | · | · | · | · | · | |
| P/E | -2.4 | -3.4 | · | -2.1 | -0.7 | -0.3 | · | · | · | · | · | |
| P/S | 110.6 | 152.1 | · | 363.7 | 225.5 | 141.3 | · | · | · | · | · | |
| P/B | 1.4 | 1.6 | · | 2.7 | 1.4 | 0.7 | · | · | · | · | · | |
| P / Tangible Book | 1.4 | 1.6 | · | 2.7 | 1.4 | 0.7 | · | · | · | · | · | |
| P / Cash Flow | · | -10.2 | · | · | · | -8.0 | · | · | · | · | · | |
| Earnings Yield | -41.2% | -29.2% | · | -47.0% | -134.0% | -304.7% | · | · | · | · | · |
Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre
Gewinn- und Verlustrechnung
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Umsatz | $3M | $2M | $2M |
| Betriebsgewinnmarge % | -5618.8% | -3281.2% | — |
| Nettoergebnis | $-143M | $-63M | $-21M |
| Verwässerte EPS | $-2.66 | $-5.58 | $-12.95 |
Bilanz
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Liquiditätsgrad | 26.2 | 44.6 | — |
| Quick Ratio | 25.4 | 43.9 | — |
Cashflow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Freier Cashflow | $-133M | $-60M | — |
Meine Kennzahlen Ihre persönliche Watchlist — ausgewählte Zeilen aus den vollständigen Fundamentaldaten
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Wählen Sie die Kennzahlen, die für Sie wichtig sind — klicken Sie auf das ➕ neben jeder Zeile in den vollständigen Fundamentaldaten oben.
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Institutionelle Eigentümer (13F) 157 Einreicher · $351.5M gesamt · Stand 30. Juni 2026
Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.
Institutionelle Aktivität — Q2 2026 vs. Vorquartal
| Neue Positionen | Geschlossene Positionen | Erhöht | Abgenommen | Nettoveränderung der Aktien |
|---|---|---|---|---|
| 45 (+1 vs. Vorquartal) | 25 (-11 vs. Vorquartal) | 59 (+14 vs. Vorquartal) | 30 (-4 vs. Vorquartal) | +6.8M |
Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.
| Institution | Wert | Aktien | % der verfolgten 13F | Typ |
|---|---|---|---|---|
| VANGUARD GROUP INC | $57.916.706 | 2.133.212 | 16,48% | Aktien |
| FMR LLC | $50.318.247 | 7.271.423 | 14,31% | Aktien |
| ORBIMED ADVISORS LLC | $39.399.636 | 5.693.589 | 11,21% | Aktien |
| NORGES BANK | $26.078.843 | 3.768.619 | 7,42% | Aktien |
| Decheng Capital LLC | $18.856.087 | 2.724.868 | 5,36% | Aktien |
| ENAVATE SCIENCES GP, LLC | $17.021.145 | 2.459.703 | 4,84% | Aktien |
| VANGUARD CAPITAL MANAGEMENT LLC | $12.986.999 | 1.876.734 | 3,69% | Aktien |
| MILLENNIUM MANAGEMENT LLC | $7.914.923 | 1.143.775 | 2,25% | Aktien |
| Qube Research & Technologies Ltd | $6.771.220 | 978.500 | 1,93% | Aktien |
| Parkman Healthcare Partners LLC | $6.471.909 | 935.247 | 1,84% | Aktien |
| SEB Asset Management AB | $6.079.022 | 878.473 | 1,73% | Aktien |
| D. E. Shaw & Co., Inc. | $5.795.971 | 837.568 | 1,65% | Aktien |
| Woodline Partners LP | $5.753.849 | 831.481 | 1,64% | Aktien |
| GEODE CAPITAL MANAGEMENT, LLC | $5.539.562 | 800.289 | 1,58% | Aktien |
| STATE STREET CORP | $5.302.955 | 766.323 | 1,51% | Aktien |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $4.931.656 | 712.667 | 1,40% | Aktien |
| Y-Intercept (Hong Kong) Ltd | $4.799.401 | 693.555 | 1,37% | Aktien |
| Bain Capital Life Sciences Investors, LLC | $4.158.567 | 600.949 | 1,18% | Aktien |
| BNP PARIBAS FINANCIAL MARKETS | $3.539.898 | 511.546 | 1,01% | Aktien |
| Walleye Capital LLC | $3.449.551 | 498.490 | 0,98% | Aktien |
| Trexquant Investment LP | $3.227.696 | 466.430 | 0,92% | Aktien |
| Point72 Asset Management, L.P. | $3.134.836 | 453.011 | 0,89% | Aktien |
| BANK OF AMERICA CORP /DE/ | $2.710.993 | 391.762 | 0,77% | Aktien |
| Altshuler Shaham Ltd | $2.630.022 | 380.061 | 0,75% | Aktien |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $2.475.672 | 357.756 | 0,70% | Aktien |
| SAMSARA BIOCAPITAL, LLC | $2.447.722 | 353.717 | 0,70% | Aktien |
| Propel Bio Management, LLC | $2.424.692 | 350.389 | 0,69% | Aktien |
| WELLINGTON MANAGEMENT GROUP LLP | $2.369.083 | 342.353 | 0,67% | Aktien |
| DIMENSIONAL FUND ADVISORS LP | $2.363.464 | 341.541 | 0,67% | Aktien |
| Squarepoint Ops LLC | $2.013.056 | 290.904 | 0,57% | Aktien |
| Voleon Capital Management LP | $1.973.819 | 285.234 | 0,56% | Aktien |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1.816.196 | 262.456 | 0,52% | Aktien |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1.751.397 | 253.092 | 0,50% | Aktien |
| GOLDMAN SACHS GROUP INC | $1.708.666 | 246.917 | 0,49% | Aktien |
| XTX Topco Ltd | $1.677.034 | 242.346 | 0,48% | Aktien |
| VANGUARD FIDUCIARY TRUST CO | $1.658.143 | 239.616 | 0,47% | Aktien |
| UBS Group AG | $1.624.200 | 234.711 | 0,46% | Aktien |
| Schonfeld Strategic Advisors LLC | $1.562.258 | 225.760 | 0,44% | Aktien |
| SPHERA FUNDS MANAGEMENT LTD. | $1.520.324 | 219.700 | 0,43% | Aktien |
| BlackRock, Inc. | $1.054.823 | 152.431 | 0,30% | Aktien |
| Boxer Capital Management, LLC | $1.038.000 | 150.000 | 0,30% | Aktien |
| RENAISSANCE TECHNOLOGIES LLC | $908.596 | 131.300 | 0,26% | Aktien |
| EntryPoint Capital, LLC | $895.766 | 129.446 | 0,25% | Aktien |
| ALGERT GLOBAL LLC | $820.920 | 118.630 | 0,23% | Aktien |
| AMERICAN CENTURY COMPANIES INC | $541.102 | 78.194 | 0,15% | Aktien |
| Man Group plc | $510.855 | 73.823 | 0,15% | Aktien |
| JPMORGAN CHASE & CO | $505.093 | 72.885 | 0,14% | Aktien |
| ALLIANCEBERNSTEIN L.P. | $465.120 | 51.680 | 0,13% | Aktien |
| Simplify Asset Management Inc. | $429.822 | 62.113 | 0,12% | Aktien |
| ALPS ADVISORS INC | $382.178 | 55.228 | 0,11% | Aktien |
| Quantinno Capital Management LP | $379.479 | 54.838 | 0,11% | Aktien |
| Nuveen Asset Management, LLC | $371.314 | 22.586 | 0,11% | Aktien |
| Virtus Investment Advisers, LLC | $371.175 | 53.638 | 0,11% | Aktien |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $356.949 | 39.661 | 0,10% | Aktien |
| Brevan Howard Capital Management LP | $348.553 | 50.369 | 0,10% | Aktien |
| Swiss National Bank | $332.852 | 48.100 | 0,09% | Aktien |
| MORGAN STANLEY | $311.220 | 44.974 | 0,09% | Aktien |
| Allspring Global Investments Holdings, LLC | $298.819 | 43.182 | 0,09% | Aktien |
| RHUMBLINE ADVISERS | $293.288 | 42.384 | 0,08% | Aktien |
| TWO SIGMA INVESTMENTS, LP | $292.889 | 42.325 | 0,08% | Aktien |
| ExodusPoint Capital Management, LP | $284.031 | 41.045 | 0,08% | Aktien |
| CITIGROUP INC | $265.084 | 38.307 | 0,08% | Aktien |
| Stonepine Capital Management, LLC | $231.349 | 33.432 | 0,07% | Aktien |
| Mariner, LLC | $229.337 | 33.141 | 0,07% | Aktien |
| DEUTSCHE BANK AG\ | $228.561 | 33.029 | 0,07% | Aktien |
| WELLS FARGO & COMPANY/MN | $204.119 | 29.497 | 0,06% | Aktien |
| Bank of New York Mellon Corp | $197.711 | 28.571 | 0,06% | Aktien |
| Quantbot Technologies LP | $194.992 | 28.178 | 0,06% | Aktien |
| BARCLAYS PLC | $193.608 | 27.978 | 0,06% | Aktien |
| AXQ CAPITAL, LP | $187.311 | 27.068 | 0,05% | Aktien |
| nVerses Capital, LLC | $166.280 | 24.029 | 0,05% | Aktien |
| DNB Asset Management AS | $163.312 | 23.600 | 0,05% | Aktien |
| VANGUARD ASSET MANAGEMENT, Ltd | $157.250 | 22.724 | 0,04% | Aktien |
| Graham Capital Management, L.P. | $155.755 | 22.508 | 0,04% | Aktien |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $154.904 | 22.385 | 0,04% | Aktien |
| Verdad Advisers, LP | $150.925 | 21.810 | 0,04% | Aktien |
| MetLife Investment Management, LLC | $144.296 | 20.852 | 0,04% | Aktien |
| SEI INVESTMENTS CO | $138.580 | 20.026 | 0,04% | Aktien |
| WINTON GROUP Ltd | $137.016 | 19.800 | 0,04% | Aktien |
| IEQ CAPITAL, LLC | $135.182 | 19.535 | 0,04% | Aktien |
| DIADEMA PARTNERS LP | $132.124 | 19.093 | 0,04% | Aktien |
| Shay Capital LLC | $124.560 | 18.000 | 0,04% | Aktien |
| Quadrature Capital Ltd | $124.477 | 17.988 | 0,04% | Aktien |
| Entropy Technologies, LP | $121.391 | 17.542 | 0,03% | Aktien |
| STATE OF WISCONSIN INVESTMENT BOARD | $118.090 | 17.065 | 0,03% | Aktien |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $112.222 | 16.217 | 0,03% | Aktien |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $108.886 | 15.735 | 0,03% | Aktien |
| CITADEL ADVISORS LLC | $103.800 | 15.000 | 0,03% | Kaufoption |
| MERCER GLOBAL ADVISORS INC /ADV | $92.396 | 13.352 | 0,03% | Aktien |
| Vanguard Global Advisers, LLC | $90.368 | 13.059 | 0,03% | Aktien |
| Engineers Gate Manager LP | $86.438 | 12.491 | 0,02% | Aktien |
| Invesco Ltd. | $84.611 | 12.227 | 0,02% | Aktien |
| STRS OHIO | $83.040 | 12.000 | 0,02% | Aktien |
| JANE STREET GROUP, LLC | $82.348 | 11.900 | 0,02% | Kaufoption |
| CANADA PENSION PLAN INVESTMENT BOARD | $79.580 | 11.500 | 0,02% | Aktien |
| HSBC HOLDINGS PLC | $77.602 | 10.793 | 0,02% | Aktien |
| JANE STREET GROUP, LLC | $77.324 | 11.174 | 0,02% | Aktien |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $75.428 | 10.017 | 0,02% | Aktien |
| PRELUDE CAPITAL MANAGEMENT, LLC | $73.006 | 10.550 | 0,02% | Aktien |
| AMERIPRISE FINANCIAL INC | $72.570 | 10.487 | 0,02% | Aktien |
Unternehmensinsider 12 Insider · 5 Führungskräfte · 7 Direktoren
| Insider | Rolle | Letzte Aktivität | Gehaltene Aktien | Käufe 12m | Verkäufe 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Everett Rand Sutherland | Chief Executive Officer | 16. Juni 2026 S | 70.812 | 0 | 2 | $-32.224 |
| Michael Gray | CFO and COO | 16. Juni 2026 S | 28.795 | 0 | 2 | $-13.118 |
| Allison Ambrose | General Counsel | 16. Juni 2026 S | 16.048 | 0 | 2 | $-7.323 |
| Aaron Deykin | Chief Medical Officer | 16. Juni 2026 S | 33.197 | 0 | 2 | $-13.765 |
| Adam Houghton | Chief Business Officer | 16. Juni 2026 S | 23.601 | 0 | 2 | $-10.764 |
| Marcella K. Ruddy | Direktor | 9. Juni 2026 A | — | 0 | 0 | $0 |
| Harold Edward Fleming | Direktor | 9. Juni 2026 A | — | 0 | 0 | $0 |
| CHIMOVITS EREZ | Direktor | 9. Juni 2026 A | 4.554.873 | 0 | 0 | $0 |
| Liam Ratcliffe | Direktor | 9. Juni 2026 A | — | 0 | 0 | $0 |
| Daniella Beckman | Direktor | 9. Juni 2026 A | — | 0 | 0 | $0 |
| Ronald C Renaud JR | Direktor | 9. Juni 2026 A | — | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | 10%-Eigentümer | 15. Oktober 2024 C | 894.733 | 0 | 0 | $0 |
Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten
Aktivisten & 5%+-Eigentümer 2 Beteiligungen
Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.
| Anmelder | Eingereicht | Beteiligung | Status | Zweck | Einreichung |
|---|---|---|---|---|---|
| AI Upstream LLC, Access Industries Holdings LLC, AI Biotechnology LLC, Access Industries Management, LLC, Len Blavatnik | 22. Oktober 2024 | — | Erste Einreichung | — | SEC |
| OrbiMed Advisors LLC, OrbiMed Capital GP VIII LLC, OrbiMed Advisors Israel II Limited, OrbiMed Israel GP II, L.P. | 17. Oktober 2024 | — | Erste Einreichung | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF-Besitz Gehalten von 32 ETFs
Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.
| Fonds | Gewicht | Anteile | Stand | Quelle |
|---|---|---|---|---|
| FMED · Fidelity Covington Trust | 0,51% | 24.900 NS | 31. Mai 2026 | N-PORT |
| SBIO · ALPS ETF Trust | 0,29% | 55.699 NS | 31. Mai 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,25% | 10.169 NS | 30. April 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,07% | 92.201 NS | 30. April 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,03% | 2.927 SH | 8. August 2026 | Täglich |
| BIB · ProShares Trust | 0,02% | 1.997 NS | 31. Mai 2026 | N-PORT |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,02% | 31.318 SH | 8. August 2026 | Täglich |
| IBB · iShares Trust | 0,02% | 264.706 SH | 8. August 2026 | Täglich |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,02% | 62.606 NS | 31. Mai 2026 | N-PORT |
| IWN · iShares Trust | 0,02% | 334.907 SH | 8. August 2026 | Täglich |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,01% | 202.528 SH | 8. August 2026 | Täglich |
| RSSL · Global X Funds | 0,01% | 14.420 NS | 30. April 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,01% | 33.677 SH | 8. August 2026 | Täglich |
| IWM · iShares Trust | 0,01% | 902.359 SH | 8. August 2026 | Täglich |
| DFAS · Dimensional ETF Trust | 0,01% | 108.557 NS | 30. April 2026 | N-PORT |
| ITWO · ProShares Trust | 0,01% | 1.544 NS | 31. Mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 161.663 NS | 31. Mai 2026 | N-PORT |
| UWM · ProShares Trust | 0,00% | 1.208 NS | 31. Mai 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,00% | 11.160 NS | 30. April 2026 | N-PORT |
| URTY · ProShares Trust | 0,00% | 1.224 NS | 31. Mai 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 1.388 NS | 31. Mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 31 NS | 31. Mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 10.145 NS | 30. April 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 2.366 NS | 30. April 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 49.987 SH | 8. August 2026 | Täglich |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 20.416 NS | 31. Mai 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 9.569 SH | 8. August 2026 | Täglich |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,00% | 34 NS | 31. Mai 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 386.877 SH | 8. August 2026 | Täglich |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1.443.025 SH | 8. August 2026 | Täglich |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 2.529 SH | 8. August 2026 | Täglich |
| VHT · VANGUARD WORLD FUND | 0,00% | 72.742 SH | 8. August 2026 | Täglich |