MIST Milestone Pharmaceuticals Inc. - Common Shares

NASDAQ · Pharmaceuticals · View on SEC EDGAR ↗
$1.09
Price · Aug 19, 2026
Fundamentals as of Aug 12, 2026

MIST Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$1.09
Market Cap
$128M
P/E (TTM)
-1.6
EPS (TTM)
$-0.75
Revenue (TTM)
Div Yield
ROE
-525.0%
Debt/Equity
52W Range
$1 – $3

MIST Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
EPS $-0.75
6-point trend, +55.9%
2020-12-31 2025-12-31
Free Cash Flow $-49M
3-point trend, +4.3%
2019-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
MIST
Peer Median
P/E (TTM)
5-point trend, +58.1%
-1.6
P/B
5-point trend, +50.5%
3.1
0.5
Price / FCF
3-point trend, +42.8%
-2.6

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
MIST
Peer Median
ROA
5-point trend, -27.7%
-66.7%
-73.1%
ROE
5-point trend, -1077.6%
-525.0%
-92.8%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
MIST
Peer Median
Current Ratio
5-point trend, -45.6%
8.0
4.8
Quick Ratio
5-point trend, -47.3%
7.6

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
MIST
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
MIST
Peer Median
EPS (Diluted)
5-point trend, +26.5%
$-0.75

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
MIST
Peer Median

MIST Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 12 analysts
  • Strong Buy 3 25.0%
  • Buy 7 58.3%
  • Hold 2 16.7%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

6 analysts · 2026-08-17
Median target $7.00 +542.1%
Mean target $6.33 +480.9%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.10%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.21 $-0.20 -0.01%
March 31, 2026 $-0.20 $0.31 -0.51%
Dec. 31, 2025 $-0.18 $-0.16 -0.02%
Sept. 30, 2025 $-0.12 $-0.17 0.05%
June 30, 2025 $-0.20 $-0.18 -0.02%
March 31, 2025 $-0.31 $-0.19 -0.12%
Dec. 31, 2024 $-0.20 $-0.16 -0.04%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 11
Annual Income Statement data for MIST
Metric Trend 20252024202320222021202020192018
R&D Expense 8-point trend, +7.5% $18M $14M $31M $40M $39M $34M $42M $17M
SG&A Expense 8-point trend, +466.0% $17M $17M $16M $16M $12M $10M $7M $3M
Operating Income 8-point trend, -160.9% $-62M $-42M $-61M $-60M $-43M $-51M $-58M $-24M
Interest Expense · · $3M · · · · ·
Interest Income 3-point trend, -26.4% $3M $4M $4M · · · · ·
Pretax Income 8-point trend, -172.8% $-63M $-42M $-60M $-58M $-43M $-50M $-55M $-23M
Income Tax 3-point trend, -123.0% · · · · · $-17.0K $-56.0K $74.0K
Net Income 8-point trend, -172.0% $-63M $-42M $-60M $-58M $-43M $-50M $-55M $-23M
EPS (Basic) 6-point trend, +55.9% $-0.75 $-0.67 $-1.39 $-1.38 $-1.02 $-1.70 · ·
EPS (Diluted) 6-point trend, +55.9% $-0.75 $-0.67 $-1.39 $-1.38 $-1.02 $-1.70 · ·
EBITDA 5-point trend, -7.2% $-62M $-42M · · $-43M $-51M $-58M ·
Balance Sheet 22
Annual Balance Sheet data for MIST
Metric Trend 20252024202320222021202020192018
Cash & Equivalents 8-point trend, -15.0% $73M $25M $14M $8M $114M $72M $120M $86M
Short-term Investments 7-point trend, +113396.6% $33M $44M $52M $57M $0 $70M · $29.0K
Inventory $648.0K · · · · · · ·
Prepaid Expense 8-point trend, +29.1% $2M $2M $3M $6M $4M $5M $2M $1M
Current Assets 8-point trend, +27.1% $112M $74M $73M $72M $119M $149M $122M $88M
PP&E (Net) 8-point trend, +1603.3% $511.0K $197.0K $277.0K $257.0K $215.0K $308.0K $405.0K $30.0K
PP&E (Gross) 8-point trend, +2136.6% $917.0K $488.0K $468.0K $377.0K $454.0K $454.0K $454.0K $41.0K
Accum. Depreciation 8-point trend, +3590.9% $406.0K $291.0K $191.0K $120.0K $239.0K $146.0K $49.0K $11.0K
Total Assets 8-point trend, +28.9% $114M $75M $75M $74M $120M $150M $123M $88M
Accounts Payable 8-point trend, +26.1% $6M $8M $7M $6M $7M $6M $8M $4M
Accrued Liabilities $8M · · · · · · ·
Current Liabilities 8-point trend, +208.4% $14M $8M $7M $6M $7M $6M $8M $5M
Capital Leases 7-point trend, +192.9% $539.0K $874.0K $1M $2M $474.0K $696.0K $184.0K ·
Other Non-current Liabilities $83.0K · · · · · · ·
Total Liabilities 8-point trend, +1483.8% $72M $62M $58M $8M $7M $7M $9M $5M
Long-term Debt 4-point trend, +57191000.00 $57M $53M $50M · · · $0 ·
Common Stock 8-point trend, +17193.7% $353M $288M $261M $274M $252M $252M $226M $2M
Paid-in Capital 8-point trend, +2314.5% $64M $40M $34M $24M $16M $9M $4M $3M
Retained Earnings 8-point trend, -639.0% $-431M $-368M $-326M $-266M $-208M $-163M $-113M $-58M
Stockholders' Equity 8-point trend, -50.0% $42M $13M $17M $66M $113M $143M $115M $84M
Liabilities + Equity 8-point trend, +28.9% $114M $75M $75M $74M $120M $150M $123M $88M
Shares Outstanding 8-point trend, +17701.4% 106,236,344 53,353,984 33,483,111 34,286,002 29,897,559 29,827,997 24,505,748 596,787
Cash Flow 11
Annual Cash Flow data for MIST
Metric Trend 20252024202320222021202020192018
D&A 8-point trend, +1040.0% $114.0K $105.0K $92.0K $89.0K $93.0K $97.0K $38.0K $10.0K
Stock-based Comp 8-point trend, +1078.7% $7M $6M $10M $9M $7M $5M $1M $633.0K
Other Non-cash 5-point trend, +126.2% $6M $7M · · $2M $-6M $3M ·
Operating Cash Flow 8-point trend, -133.0% $-49M $-29M $-46M $-52M $-33M $-51M $-51M $-21M
CapEx 6-point trend, +5940.0% $302.0K $33.0K $112.0K $272.0K · · $413.0K $5.0K
Investing Cash Flow 8-point trend, -29.7% $11M $8M $5M $-57M $70M $-70M $-384.0K $16M
Stock Issued 4-point trend, +50.9% $38M $27M · $3M · $25M · ·
Net Stock Activity 3-point trend, +50.9% $38M $27M · · · $25M · ·
Financing Cash Flow 8-point trend, +6.8% $86M $32M $48M $3M $5M $73M $85M $80M
Net Change in Cash 8-point trend, -36.4% $48M $12M $6M $-107M $42M $-48M $34M $75M
Free Cash Flow 3-point trend, +4.3% $-49M $-29M · · · · $-52M ·
Profitability 3
Annual Profitability data for MIST
Metric Trend 20252024202320222021202020192018
ROA 5-point trend, -27.7% -66.7% -55.1% · · -31.8% -36.5% -52.2% ·
ROE 5-point trend, -1077.6% -525.0% -223.5% · · -35.7% -40.7% -44.6% ·
ROIC 2-point trend, +29.6% · · · · · -35.4% -50.3% ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for MIST
Metric Trend 20252024202320222021202020192018
Current Ratio 5-point trend, -45.6% 8.0 9.1 · · 17.6 24.1 14.7 ·
Quick Ratio 5-point trend, -47.3% 7.6 8.6 · · 16.8 23.1 14.4 ·
Per Share 3
Annual Per Share data for MIST
Metric Trend 20252024202320222021202020192018
Book Value / Share 5-point trend, -91.6% $0.39 $0.25 · · $3.77 $4.80 $4.69 ·
Cash / Share 5-point trend, -85.9% $0.69 $0.47 · · $3.82 $2.42 $4.89 ·
EPS (TTM) 6-point trend, +55.9% $-0.75 $-0.67 $-1.39 $-1.38 $-1.02 $-1.70 · ·
Valuation (TTM) 8
Annual Valuation (TTM) data for MIST
Metric Trend 20252024202320222021202020192018
Net Income TTM 7-point trend, -14.2% $-63M $-42M $-60M $-58M $-43M $-50M $-55M ·
Market Cap 5-point trend, -45.3% $215M $126M · · $196M $200M $392M ·
P/E 6-point trend, +31.7% -2.7 -3.5 -1.2 -2.9 -6.4 -3.9 · ·
P/B 5-point trend, +50.5% 5.1 9.6 · · 1.7 1.4 3.4 ·
P / Tangible Book 6-point trend, +267.9% 5.1 9.6 3.3 2.0 1.7 1.4 · ·
P / Cash Flow 5-point trend, +42.9% -4.4 -4.4 · · -5.9 -3.9 -7.7 ·
P / FCF 3-point trend, +42.8% -4.3 -4.4 · · · · -7.6 ·
Earnings Yield 6-point trend, -46.4% -37.1% -28.4% -83.2% -34.8% -15.6% -25.4% · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-63M$-42M$-60M$-58M$-43M
Diluted EPS $-0.75$-0.67$-1.39$-1.38$-1.02
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 8.09.117.6
Quick Ratio 7.68.616.8
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-49M$-29M

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Institutional owners (13F) 90 filers · $53.0M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
10 (-11 vs prior Q) 11 (-2 vs prior Q) 23 (+2 vs prior Q) 25 (+3 vs prior Q) +10.4M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
RTW INVESTMENTS, LP $10,496,670 7,833,336 19.79% Shares
Propel Bio Management, LLC $9,955,651 7,429,590 18.77% Shares
Point72 Asset Management, L.P. $7,250,925 5,411,138 13.67% Shares
Simplify Asset Management Inc. $4,488,168 3,349,379 8.46% Shares
MILLENNIUM MANAGEMENT LLC $4,210,573 3,142,219 7.94% Shares
TWO SIGMA INVESTMENTS, LP $2,733,620 2,040,015 5.15% Shares
Kalehua Capital Management LLC $1,700,778 1,269,237 3.21% Shares
TWO SIGMA ADVISERS, LP $1,251,576 619,592 2.36% Shares
Lion Point Capital, LP $1,098,800 820,000 2.07% Shares
TORONTO DOMINION BANK $1,005,000 750,000 1.89% Shares
Boxer Capital Management, LLC $893,332 666,666 1.68% Shares
AMERIPRISE FINANCIAL INC $893,332 666,666 1.68% Shares
BOOTHBAY FUND MANAGEMENT, LLC $619,976 462,669 1.17% Shares
UBS Group AG $554,345 413,690 1.05% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $482,259 359,895 0.91% Shares
AMH Equity Ltd $463,342 231,671 0.87% Shares
GUARDIAN WEALTH ADVISORS, LLC / NC $454,863 339,450 0.86% Shares
Aptus Capital Advisors, LLC $454,863 339,450 0.86% Shares
Seven Fleet Capital Management LP $362,112 270,233 0.68% Shares
Squarepoint Ops LLC $310,644 231,824 0.59% Shares
LPL Financial LLC $295,970 220,873 0.56% Shares
Balyasny Asset Management L.P. $295,467 220,498 0.56% Shares
BNP PARIBAS FINANCIAL MARKETS $232,763 173,704 0.44% Shares
CITADEL ADVISORS LLC $220,162 164,300 0.42% Put option
TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC $201,000 150,000 0.38% Shares
Wealthspire Advisors, LLC $188,443 140,629 0.36% Shares
Valeo Financial Advisors, LLC $175,137 130,699 0.33% Shares
ADAR1 Capital Management, LLC $134,000 100,000 0.25% Shares
Cascades Capital Asset Management, LLC $112,037 83,610 0.21% Shares
Quadrature Capital Ltd $86,646 64,661 0.16% Shares
JANE STREET GROUP, LLC $77,435 57,787 0.15% Shares
CITADEL ADVISORS LLC $75,174 56,100 0.14% Call option
SIMPLEX TRADING, LLC $72,589 54,171 0.14% Shares
Bay Rivers Group $62,488 46,633 0.12% Shares
GEODE CAPITAL MANAGEMENT, LLC $54,657 40,789 0.10% Shares
October Effect Ltd $53,600 40,000 0.10% Shares
Focus Partners Wealth $48,240 36,000 0.09% Shares
MORGAN STANLEY $42,244 31,525 0.08% Shares
CITADEL ADVISORS LLC $42,138 31,446 0.08% Shares
JANE STREET GROUP, LLC $41,808 31,200 0.08% Put option
Mariner, LLC $37,192 27,830 0.07% Shares
RAYMOND JAMES FINANCIAL INC $35,644 26,600 0.07% Shares
XTX Topco Ltd $35,265 26,317 0.07% Shares
MARSHALL WACE, LLP $34,335 25,623 0.06% Shares
Welch & Forbes LLC $33,500 25,000 0.06% Shares
Tower Research Capital LLC (TRC) $32,408 24,185 0.06% Shares
NATIONAL BANK OF CANADA /FI/ $31,490 23,500 0.06% Shares
Exit Wealth Advisors, LLC. $30,407 22,692 0.06% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $30,284 22,600 0.06% Put option
STATE STREET CORP $30,236 22,564 0.06% Shares
Stephenson & Company, Inc. $26,800 20,000 0.05% Shares
Taylor Financial Group, Inc. $26,800 20,000 0.05% Shares
HighTower Advisors, LLC $26,800 20,000 0.05% Shares
JOURNEY STRATEGIC WEALTH LLC $23,800 20,000 0.04% Shares
Federation des caisses Desjardins du Quebec $22,487 16,781 0.04% Shares
TWO SIGMA SECURITIES, LLC $22,438 16,745 0.04% Shares
Cetera Investment Advisers $21,933 16,368 0.04% Shares
JANE STREET GROUP, LLC $21,440 16,000 0.04% Call option
Pathstone Holdings, LLC $20,770 15,500 0.04% Shares
AE Wealth Management LLC $20,100 15,000 0.04% Shares
Vision Retirement, LLC $20,100 15,000 0.04% Shares
JONES FINANCIAL COMPANIES LLLP $19,840 16,000 0.04% Shares
EARNED WEALTH ADVISORS, LLC $19,773 14,756 0.04% Shares
Bronte Capital Management Pty Ltd. $19,283 14,390 0.04% Shares
WINTON GROUP Ltd $19,162 14,300 0.04% Shares
Beta Wealth Group, Inc. $18,930 14,127 0.04% Shares
Strategic Family Wealth Counselors, L.L.C. $18,593 13,875 0.04% Shares
Creative Planning $17,527 13,080 0.03% Shares
Rockefeller Capital Management L.P. $16,750 12,500 0.03% Shares
Safeguard Investment Advisory Group, LLC $16,624 12,406 0.03% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $16,482 12,300 0.03% Call option
Eaton Financial Holdings Company, LLC $13,735 10,250 0.03% Shares
INTEGRAL INVESTMENT ADVISORS, INC. $13,400 10,000 0.03% Shares
Secure Asset Management, LLC $13,400 10,000 0.03% Shares
CWM, LLC $11,900 10,000 0.02% Shares
ROYAL BANK OF CANADA $9,000 6,458 0.02% Shares
US BANCORP \DE\ $4,288 3,200 0.01% Shares
Arax Advisory Partners $4,090 3,053 0.01% Shares
PNC Financial Services Group, Inc. $3,752 2,800 0.01% Shares
Aptus Capital Advisors, LLC $670 500 0.00% Call option
Medallion Wealth Advisors, LLC $456 340 0.00% Shares
Rialto Wealth Management, LLC $402 300 0.00% Shares
GROUP ONE TRADING LLC $300 224 0.00% Shares
MERCER GLOBAL ADVISORS INC /ADV $165 123 0.00% Shares
Caitong International Asset Management Co., Ltd $126 94 0.00% Shares
OLIVER LAGORE VANVALIN INVESTMENT GROUP $80 100 0.00% Shares
SG Americas Securities, LLC $61 45,574 0.00% Shares
Cambridge Investment Research Advisors, Inc. $18 13,480 0.00% Shares
Virtu Financial LLC $16 11,613 0.00% Shares
SBI Securities Co., Ltd. $8 6 0.00% Shares

Company insiders 22 insiders · 8 officers · 12 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Joseph Oliveto President and CEO Feb. 16, 2023 A 280,555 0 0 $0
Amit Hasija CFO & EVP of Corp. Development Feb. 16, 2023 A 0 0 $0
Jeffrey Edward Nelson Chief Operating Officer Feb. 16, 2023 A 0 0 $0
David Bharucha Chief Medical Officer Feb. 16, 2023 A 10,000 0 0 $0
Lorenz Muller Chief Commercial Officer Feb. 16, 2023 A 108,386 0 0 $0
Francis Plat Chief Medical Officer March 24, 2021 A 0 0 $0
Timothy Maness Chief Accounting Officer Sept. 9, 2019 A 0 0 $0
Philippe Douville Chief Scientific Officer May 13, 2019 C 43,392 0 0 $0
Stuart Duty Director June 10, 2026 A 0 0 $0
Robert James Wills Director June 10, 2026 A 15,000 0 0 $0
Andrew Saik Director June 10, 2026 A 0 0 $0
Seth H. Z. Fischer Director June 10, 2026 A 0 0 $0
Michael John Tomsicek Director June 10, 2026 A 15,000 0 0 $0
Lisa M. Giles Director June 10, 2026 A 0 0 $0
Joseph C Papa Director June 10, 2026 A 0 0 $0
Richard C Pasternak Director June 7, 2023 A 10,000 0 0 $0
Debra K. Liebert Director June 7, 2023 A 4,000 0 0 $0
Paul F Truex Director May 31, 2022 M 81,780 0 0 $0
Paul R Edick Director June 5, 2020 A 0 0 $0
FONDS DE SOLIDARITE DES TRAVAILLEURS DU QUEBEC 10% owner July 29, 2020 S 2,254,920 0 0 $0
Novo Holdings A/S 10% owner Nov. 25, 2019 S 2,434,470 0 0 $0
BDC CAPITAL INC. 10% owner May 8, 2019 P 2,388,088 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 2 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Alta Fundamental Advisers LLC, Gilbert Li, Jeremy Carton ×2 filings July 16, 2024 Initial filing Board campaign SEC
Novo Holdings A/S ×6 filings Oct. 24, 2022 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.