SERA Sera Prognostics, Inc. - Class A Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$1.96
Price · Aug 17, 2026
Fundamentals as of Aug 12, 2026

SERA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$1.96
Market Cap
P/E (TTM)
-4.4
EPS (TTM)
$-0.67
Revenue (TTM)
$81.0K
Div Yield
ROE
-39.0%
Debt/Equity
52W Range
$2 – $4

SERA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $81.0K
6-point trend, +224.0%
2020-12-31 2025-12-31
EPS $-0.67
6-point trend, +94.7%
2020-12-31 2025-12-31
Free Cash Flow $-26M
5-point trend, +20.0%
2021-12-31 2025-12-31
Margins -39417.3%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
SERA
Peer Median
P/E (TTM)
5-point trend, -49.3%
-4.4
2.6

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
SERA
Peer Median
Operating Margin
5-point trend, -4.4%
-45066.7%
Net Profit Margin
5-point trend, +7.7%
-39417.3%
-351.5%
ROA
5-point trend, +15.4%
-36.6%
-60.9%
ROE
5-point trend, -60.8%
-39.0%
-99.5%
ROIC
-48.4%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
SERA
Peer Median
Current Ratio
5-point trend, -87.1%
1.7
2.6
Quick Ratio
5-point trend, -87.0%
1.6

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
SERA
Peer Median
Revenue YoY
5-point trend, -1.2%
5.2%
Revenue CAGR 3Y
5-point trend, -1.2%
-32.9%
Revenue CAGR 5Y
5-point trend, -1.2%
26.5%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
SERA
Peer Median
EPS (Diluted)
5-point trend, +71.2%
$-0.67

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
SERA
Peer Median

SERA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 10 analysts
  • Strong Buy 4 40.0%
  • Buy 5 50.0%
  • Hold 1 10.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

2 analysts · 2026-08-18
Median target $5.50 +180.6%
Mean target $5.50 +180.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.02%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.18 $-0.16 -0.02%
March 31, 2026 $-0.17 $-0.17 0.00%
Dec. 31, 2025 $-0.16 $-0.19 0.03%
Sept. 30, 2025 $-0.16 $-0.20 0.04%
June 30, 2025 $-0.16 $-0.23 0.07%
March 31, 2025 $-0.20 $-0.23 0.03%
Dec. 31, 2024 $-0.25 $-0.24 -0.01%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
SERA -4.4 5.2% -39417.3% -39.0%
KLRS $193M -3.0 -65.8%
ACRV $76M -1.2 -61.0%
ATRA $132M 7.0 -6.3% 27.1% -88.9%
ACET -0.5
ELTX -3.1
FRMM -6881.3% -368.1%
ANVS $94M -2.5 -164.0%
CYPH $97M 16.6 6.1%
NMAD

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for SERA
Metric Trend 202520242023202220212020
Revenue 6-point trend, +224.0% $81.0K $77.0K $306.0K $268.0K $82.0K $25.0K
Cost of Revenue 3-point trend, -21.9% $164.0K $82.0K $210.0K · · ·
R&D Expense 6-point trend, +69.2% $13M $15M $15M $14M $11M $8M
SG&A Expense 6-point trend, +154.7% $17M $16M $16M $17M $14M $7M
Operating Expenses 6-point trend, +103.3% $37M $37M $40M $46M $35M $18M
Operating Income 6-point trend, -103.1% $-37M $-37M $-40M $-46M $-35M $-18M
Interest Expense 3-point trend, -83.6% $9.0K $28.0K $55.0K · · ·
Other Non-op 6-point trend, +12165.8% $5M $4M $4M $2M $1M $-38.0K
Pretax Income 2-point trend, +2.9% $-32M $-33M · · · ·
Income Tax Flat — no change across 6 periods $0 $0 $0 $0 $0 $0
Net Income 6-point trend, -60.9% $-32M $-33M $-36M $-44M $-35M $-20M
EPS (Basic) 6-point trend, +94.7% $-0.67 $-0.99 $-1.16 $-1.43 $-2.33 $-12.76
EPS (Diluted) 6-point trend, +94.7% $-0.67 $-0.99 $-1.16 $-1.43 $-2.33 $-12.76
Shares (Basic) 6-point trend, +2963.6% 47,662,078 33,156,936 31,200,652 30,943,426 15,003,144 1,555,745
Shares (Diluted) 6-point trend, +2963.6% 47,662,078 33,156,936 31,200,652 30,943,426 15,003,144 1,555,745
EBITDA 5-point trend, -2.4% $-36M $-36M $-39M $-45M $-35M ·
Balance Sheet 21
Annual Balance Sheet data for SERA
Metric Trend 202520242023202220212020
Cash & Equivalents 6-point trend, -70.9% $4M $4M $4M $30M $59M $14M
Short-term Investments 6-point trend, +35257000.00 $35M $42M $45M $53M $46M $0
Receivables 6-point trend, +500.0% $12.0K $34.0K $160.0K $113.0K $27.0K $2.0K
Prepaid Expense 6-point trend, +686.4% $2M $1M $795.0K $1M $2M $198.0K
Current Assets 6-point trend, +196.9% $41M $48M $61M $90M $110M $14M
PP&E (Net) 2-point trend, +83.7% · · · · $2M $965.0K
PP&E (Gross) 2-point trend, +22.3% · · · · $8M $6M
Accum. Depreciation 2-point trend, +11.3% · · · · $6M $5M
Intangibles 3-point trend, +910000.00 $910.0K $1M $0 · · ·
Other Non-current Assets 6-point trend, +2476.5% $3M $737.0K $1M $2M $157.0K $98.0K
Total Assets 6-point trend, +588.9% $102M $73M $95M $116M $147M $15M
Accounts Payable 6-point trend, +95.5% $862.0K $2M $1M $2M $1M $441.0K
Current Liabilities 6-point trend, +115.2% $24M $25M $24M $16M $8M $11M
Capital Leases 6-point trend, +1740.2% $2M $0 $644.0K $1M $0 $127.0K
Total Liabilities 6-point trend, +115.1% $27M $25M $25M $17M $8M $12M
Common Stock 6-point trend, +4000.00 $4.0K $3.0K $3.0K $3.0K $3.0K $0
Paid-in Capital 6-point trend, +6469.3% $387M $328M $317M $311M $305M $6M
Retained Earnings 6-point trend, -137.1% $-312M $-280M $-247M $-211M $-166M $-131M
AOCI 6-point trend, +262000.00 $262.0K $60.0K $-15.0K $-981.0K $-183.0K $0
Stockholders' Equity 6-point trend, +160.1% $75M $48M $70M $99M $139M $-126M
Liabilities + Equity 6-point trend, +588.9% $102M $73M $95M $116M $147M $15M
Cash Flow 13
Annual Cash Flow data for SERA
Metric Trend 202520242023202220212020
D&A 6-point trend, +5.0% $940.0K $833.0K $900.0K $756.0K $659.0K $895.0K
Stock-based Comp 6-point trend, +603.9% $5M $7M $5M $5M $3M $726.0K
Deferred Tax Flat — no change across 6 periods $0 $0 $0 $0 $0 $0
Amort. of Intangibles 2-point trend, +510.5% $116.0K $19.0K · · · ·
Other Non-cash 5-point trend, +161.3% $255.0K $11M $3M $4M $-416.0K ·
Operating Cash Flow 6-point trend, -51.9% $-26M $-14M $-27M $-35M $-32M $-17M
CapEx 6-point trend, +387.2% $726.0K $56.0K $128.0K $791.0K $1M $149.0K
Investing Cash Flow 6-point trend, -19028.9% $-29M $12M $438.0K $6M $-83M $-149.0K
Stock Issued $54M · · · · ·
Net Stock Activity $54M · · · · ·
Financing Cash Flow 6-point trend, +489.8% $54M $3M $752.0K $5.0K $160M $9M
Free Cash Flow 5-point trend, +20.0% $-26M $-14M $-27M $-35M $-33M ·
Levered FCF $-26M · · · · ·
Profitability 7
Annual Profitability data for SERA
Metric Trend 202520242023202220212020
Operating Margin 5-point trend, -4.4% -45066.7% -47577.9% -13013.4% -17034.3% -43164.6% ·
Net Margin 5-point trend, +7.7% -39417.3% -42724.7% -11843.8% -16487.3% -42693.9% ·
Pretax Margin -39417.3% · · · · ·
EBITDA Margin 5-point trend, -3.6% -43906.2% -46496.1% -12719.3% -16752.2% -42361.0% ·
ROA 5-point trend, +15.4% -36.6% -39.2% -34.2% -33.6% -43.3% ·
ROE 5-point trend, -60.8% -39.0% -64.2% -49.8% -42.9% -24.3% ·
ROIC -48.4% · · · · ·
Liquidity & Solvency 3
Annual Liquidity & Solvency data for SERA
Metric Trend 202520242023202220212020
Current Ratio 5-point trend, -87.1% 1.7 1.9 2.5 5.8 13.1 ·
Quick Ratio 5-point trend, -87.0% 1.6 1.9 2.0 5.3 12.5 ·
Interest Coverage 2-point trend, -210.0% -4056.0 -1308.4 · · · ·
Efficiency 2
Annual Efficiency data for SERA
Metric Trend 202520242023202220212020
Asset Turnover 5-point trend, -10.0% 0.0 0.0 0.0 0.0 0.0 ·
Receivables Turnover 5-point trend, -37.7% 3.5 0.8 2.2 3.8 5.7 ·
Per Share 3
Annual Per Share data for SERA
Metric Trend 202520242023202220212020
Revenue / Share 5-point trend, -69.1% $0.00 $0.00 $0.01 $0.01 $0.01 ·
Cash Flow / Share 5-point trend, +74.5% $-0.54 $-0.43 $-0.87 $-1.12 $-2.11 ·
EPS (TTM) 5-point trend, +71.2% $-0.67 $-0.99 $-1.16 $-1.43 $-2.33 ·
Growth Rates 3
Annual Growth Rates data for SERA
Metric Trend 202520242023202220212020
Revenue YoY 5-point trend, -97.7% 5.2% -74.8% 14.2% 226.8% 228.0% ·
Revenue CAGR 3Y 3-point trend, -125.2% -32.9% -2.1% 130.5% · · ·
Revenue CAGR 5Y 26.5% · · · · ·
Valuation (TTM) 4
Annual Valuation (TTM) data for SERA
Metric Trend 202520242023202220212020
Revenue TTM 5-point trend, -1.2% $81.0K $77.0K $306.0K $268.0K $82.0K ·
Net Income TTM 5-point trend, +8.8% $-32M $-33M $-36M $-44M $-35M ·
P/E 5-point trend, -49.3% -4.4 -8.2 -5.2 -0.9 -2.9 ·
Earnings Yield 5-point trend, +33.0% -22.7% -12.2% -19.4% -113.5% -33.9% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $81.0K$77.0K$306.0K$268.0K$82.0K
Operating Margin % -45066.7%-47577.9%-13013.4%-17034.3%-43164.6%
Net Income $-32M$-33M$-36M$-44M$-35M
Diluted EPS $-0.67$-0.99$-1.16$-1.43$-2.33
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 1.71.92.55.813.1
Quick Ratio 1.61.92.05.312.5
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-26M$-14M$-27M$-35M$-33M

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Institutional owners (13F) 54 filers · $31.4M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
5 (-5 vs prior Q) 9 (-2 vs prior Q) 9 (+2 vs prior Q) 13 (-1 vs prior Q) -1.5M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BAKER BROS. ADVISORS LP $10,006,669 5,498,170 31.91% Shares
Whetstone Capital Advisors, LLC $6,018,538 3,306,889 19.19% Shares
Aberdeen Group plc $5,011,416 2,753,525 15.98% Shares
Vivo Capital, LLC $3,003,801 1,650,440 9.58% Shares
VANGUARD CAPITAL MANAGEMENT LLC $2,361,981 1,297,792 7.53% Shares
CAPTRUST FINANCIAL ADVISORS $975,074 535,755 3.11% Shares
GEODE CAPITAL MANAGEMENT, LLC $509,821 279,927 1.63% Shares
VANGUARD GROUP INC $500,500 169,661 1.60% Shares
AWM Investment Company, Inc. $377,435 207,382 1.20% Shares
VANGUARD FIDUCIARY TRUST CO $311,053 170,908 0.99% Shares
Nuveen Asset Management, LLC $304,574 37,417 0.97% Shares
STATE STREET CORP $227,121 124,792 0.72% Shares
MILLENNIUM MANAGEMENT LLC $134,655 73,986 0.43% Shares
Perigon Wealth Management, LLC $132,287 72,685 0.42% Shares
NORTHERN TRUST CORP $124,843 68,595 0.40% Shares
Bank of New York Mellon Corp $107,307 58,960 0.34% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $101,383 55,705 0.32% Shares
Requisite Capital Management, LLC $101,279 55,648 0.32% Shares
MORGAN STANLEY $92,769 50,972 0.30% Shares
Qube Research & Technologies Ltd $92,585 50,871 0.30% Shares
Ballentine Partners, LLC $90,388 49,664 0.29% Shares
Twelve Points Wealth Management LLC $78,966 43,388 0.25% Shares
HighTower Advisors, LLC $76,866 42,234 0.25% Shares
CITADEL ADVISORS LLC $75,368 41,411 0.24% Shares
Catalyst Funds Management Pty Ltd $70,780 38,890 0.23% Shares
GOLDMAN SACHS GROUP INC $59,225 32,541 0.19% Shares
Birch Hill Investment Advisors LLC $49,673 27,293 0.16% Shares
Cetera Investment Advisers $45,500 25,000 0.15% Shares
DIMENSIONAL FUND ADVISORS LP $42,830 23,533 0.14% Shares
Point72 Asia (Singapore) Pte. Ltd. $31,404 10,263 0.10% Shares
XTX Topco Ltd $30,591 16,808 0.10% Shares
TWO SIGMA INVESTMENTS, LP $29,522 16,221 0.09% Shares
Riverview Capital Advisers, LLC $23,058 12,669 0.07% Shares
Wagner Wealth Management, LLC $22,568 12,400 0.07% Shares
Focus Partners Wealth $22,124 12,156 0.07% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $20,693 10,504 0.07% Shares
UBS Group AG $20,510 11,269 0.07% Shares
Vanguard Global Advisers, LLC $20,328 11,169 0.06% Shares
Geneos Wealth Management Inc. $19,656 10,800 0.06% Shares
BlackRock, Inc. $12,691 6,973 0.04% Shares
Cubist Systematic Strategies, LLC $7,124 2,328 0.02% Shares
BARCLAYS PLC $5,786 3,179 0.02% Shares
FMR LLC $4,621 2,539 0.01% Shares
CWM, LLC $2,036 1,003 0.01% Shares
Global Retirement Partners, LLC $1,820 1,000 0.01% Shares
Point72 (DIFC) Ltd $713 233 0.00% Shares
JPMORGAN CHASE & CO $402 222 0.00% Shares
BNP PARIBAS FINANCIAL MARKETS $339 186 0.00% Shares
NISA INVESTMENT ADVISORS, LLC $235 129 0.00% Shares
Silicon Valley Capital Partners $116 57 0.00% Shares
Caitong International Asset Management Co., Ltd $7 4 0.00% Shares
SBI Securities Co., Ltd. $7 4 0.00% Shares
MERCER GLOBAL ADVISORS INC /ADV $5 3 0.00% Shares
ROYAL BANK OF CANADA $0 45 0.00% Shares

Company insiders 19 insiders · 10 officers · 10 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Zhenya Lindgardt Chief Executive Officer June 11, 2026 S 865,009 0 8 $-246,362
Austin Aerts Chief Financial Officer June 11, 2026 S 301,190 0 9 $-68,639
Jay M Moyes Chief Financial Officer July 19, 2021 C 2,830 0 0 $0
Tiffany Eul Davis Inglis Chief Medical Officer June 11, 2026 S 92,075 0 1 $-728
Dyaarl Lee Anderson Jr. Chief Commercial Officer June 11, 2026 S 77,998 0 1 $-9,525
Benjamin Jackson General Counsel June 11, 2026 S 161,756 0 6 $-36,959
Paul Kearney Chief Data Officer March 11, 2026 S 163,961 0 7 $-134,991
John J. Boniface Chief Scientific Officer March 11, 2026 S 145,842 0 5 $-38,174
Robert Gardner Harrison Chief Information Officer March 11, 2026 S 76,712 0 11 $-64,188
Thomas Garite VP, Clinical Sciences Aug. 26, 2021 A 0 0 $0
Joshua Phillips Director July 10, 2026 A 81,691 0 0 $0
Jane F Barlow Director July 10, 2026 A 47,088 0 0 $0
Mansoor Raza Mirza Director July 10, 2026 A 81,937 0 3 $-2,280
Kim P. Kamdar Director July 10, 2026 A 58,420 0 0 $0
Mark Christopher Capone Director July 10, 2026 A 44,379 0 0 $0
Sandra Aj Lawrence Director July 10, 2026 A 41,175 0 5 $-27,804
Gregory C Critchfield Director July 10, 2026 A 846,886 0 0 $0
Jeffrey Thomas Elliott Director June 4, 2026 0 0 $0
Ryan Trimble Director June 5, 2025 A 22,713 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 2 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker, Felix J. Baker Feb. 14, 2025 16.10% Initial filing SEC
Chione Ltd., Marcin Czernik, Andreas Hadjimichael, Anastasis Nikolaou, Wiaczeslaw Smolokowski ×2 filings Feb. 14, 2025 7.60% Amendment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 4 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IWC · iShares Trust 0.01% 102,359 SH Aug. 8, 2026 Daily
AVSC · AMERICAN CENTURY ETF TRUST 0.00% 5,403 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.00% 380,212 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 887,016 SH Aug. 8, 2026 Daily