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SPRO NASDAQ US

Spero Therapeutics, Inc. - Common Stock

Healthcare · Biotechnology Website · IPO Nov 2017
$2.43
▼ $-0.02 (-0.82%)
Vol 214K
5
Quality Score
fail
Mkt Cap
$131.3M
ROE
-125.9%
Margin
-108.1%
D/E
0.00
Beta
1.44
52W
$1–$3

Wall Street Consensus

6 analysts · Apr 2026
0
Strong Buy
0
Buy
3
Hold
1
Sell
2
Strong Sell
0.0%
Buy Rating

Price Chart

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Earnings

Beat rate: 80.0%
Next Report May 11, 2026
EPS Estimate: $-0.18
Quarter EPS Est EPS Act Surprise
Mar 2026 $-0.18 — —
Dec 2025 $-0.20 $0.53 +$0.73
Sep 2025 $-0.26 $-0.13 +$0.13
Jun 2025 $-0.39 $-0.03 +$0.36

Fundamentals Trend

Metric 2025-06-30 2025-09-02 2025-10-02 2025-11-03 2025-12-03 2026-01-02
ROE (TTM) -120.3% -120.3% -120.3% -120.3% -120.3% -125.9%
P/E (TTM) — — — — — —
Net Margin -12.0% -110.3% -110.3% -110.3% -110.3% -108.1%
Gross Margin — — — — — —
D/E Ratio 0.00 0.00 0.00 0.00 0.00 0.00
Current Ratio 3.97 3.97 3.97 3.97 3.97 3.83

Key Ratios

ROA (TTM)
-57.6%
P/S (TTM)
3.24
P/B
1.2
EPS (TTM)
$-0.79
CF/Share
$-0.02
Rev Growth 3Y
+38.0%
52W High
$3.22
52W Low
$0.51
$0.51 52-Week Range $3.22

How does SPRO compare to Biotechnology peers?

Peer group: Micro-cap Biotechnology (All) · 528 companies

SPRO AAPG ABEO ABOS ABP

SPRO valuation vs Biotechnology peers

P/E ratio
—
▼ 0% below peers (18.8)
vs Peers
vs Industry
Undervalued
P/S ratio
3.2
▼ 75% below peers (12.9)
vs Peers
vs Industry
Undervalued
P/B ratio
1.2
▼ 51% below peers (2.5)
vs Peers
vs Industry
Undervalued
Div yield
—
▼ 0% below peers (0.0%)
vs Peers
vs Industry
Low yield

SPRO profitability vs Biotechnology peers

ROE
-125.9%
▼ 87% below peers (-67.3%)
vs Peers
vs Industry
Weak
Net margin
-108.1%
▲ 62% above peers (-286.8%)
vs Peers
vs Industry
Below avg
Gross margin
—
▼ 0% below peers (78.6%)
vs Peers
vs Industry
In line
ROA
-57.6%
▼ 23% below peers (-46.7%)
vs Peers
vs Industry
Below avg

SPRO financial health vs Biotechnology peers

D/E ratio
0.0
▼ 0% below peers (0.0)
vs Peers
vs Industry
Low debt
Current ratio
3.8
▼ 14% below peers (4.4)
vs Peers
vs Industry
In line
Beta
1.4
▲ 49% above peers (1.0)
vs Peers
vs Industry
More volatile

SPRO fundamentals radar

SPRO Peer median Industry

SPRO profitability vs leverage

Bubble size = market cap · X = net margin · Y = D/E ratio

SPRO vs peers: key metrics

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