UNCY Unicycive Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$5.72
Price · Aug 19, 2026
Fundamentals as of Aug 12, 2026

UNCY Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$5.72
Market Cap
$126M
P/E (TTM)
-3.4
EPS (TTM)
$-1.67
Revenue (TTM)
Div Yield
ROE
-113.9%
Debt/Equity
52W Range
$4 – $9

UNCY Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
2-point trend, -29.0%
2022-12-31 2023-12-31
EPS $-1.67
5-point trend, -94.2%
2021-12-31 2025-12-31
Free Cash Flow $-31M
4-point trend, -100.2%
2022-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
UNCY
Peer Median
P/E (TTM)
5-point trend, +85.6%
-3.4
P/B
5-point trend, -77.5%
4.2
1.2
Price / FCF
4-point trend, +22.5%
-4.0

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
UNCY
Peer Median
ROA
5-point trend, +37.8%
-65.7%
-85.8%
ROE
5-point trend, -101.8%
-113.9%
-122.3%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
UNCY
Peer Median
Current Ratio
5-point trend, -70.4%
2.6
4.5
Quick Ratio
5-point trend, -72.3%
2.2

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
UNCY
Peer Median
Revenue YoY
2-point trend, -29.0%
-29.0%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
UNCY
Peer Median
EPS (Diluted)
5-point trend, -94.2%
$-1.67

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
UNCY
Peer Median

UNCY Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 15 analysts
  • Strong Buy 3 20.0%
  • Buy 11 73.3%
  • Hold 1 6.7%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

10 analysts · 2026-08-19
Median target $27.50 +380.8%
Mean target $32.40 +466.4%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.16%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.54 $-0.49 -0.05%
Dec. 31, 2025 $-0.82 $-0.48 -0.34%
Sept. 30, 2025 $-0.33 $-0.57 0.24%
June 30, 2025 $-0.52 $-0.75 0.23%
March 31, 2025 $-0.50 $-1.16 0.66%
Dec. 31, 2024 $-2.60 $-0.92 -1.7%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
UNCY $128M -3.5 -29.0% -113.9%
CRBU $151M -1.0 11.7% -1327.4% -102.8%
OKUR -0.7 -1733.7% -88.6%
CNTN $112M -2.7 -18.0%
TNYA $154M -1.2 -81.2%
CNTB $159M -2.8 -99.8% -86687.5% -97.9%
SPRB $120M -1.7 -51.3% -139.9%
EQ $95M -4.0 13.9% -133.1%
IMDX $215M -4.5 115.6% -1238.5% 330.8% 56.7%
HURA -1.2

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for UNCY
Metric Trend 2025202420232022
Revenue 2-point trend, -29.0% · · $675.0K $951.0K
R&D Expense 4-point trend, -26.7% $9M $20M $13M $12M
SG&A Expense 4-point trend, +210.6% $20M $12M $9M $7M
Operating Expenses 4-point trend, +55.3% $30M $32M $21M $19M
Operating Income 4-point trend, -63.5% $-30M $-32M $-21M $-18M
Interest Expense 2-point trend, +1266.7% · · $82.0K $6.0K
Interest Income 3-point trend, +64.6% $1M $1M $615.0K ·
Other Non-op 4-point trend, +49466.7% $3M $-5M $-10M $-6.0K
Net Income 4-point trend, -47.1% $-27M $-37M $-31M $-18M
EPS (Basic) 4-point trend, -39.2% $-1.67 $-5.65 $-1.28 $-1.20
EPS (Diluted) 4-point trend, -39.2% $-1.67 $-5.65 $-1.28 $-1.20
Shares (Basic) 4-point trend, +5.5% 15,886,876 6,698,513 24,539,309 15,057,049
Shares (Diluted) 4-point trend, +5.5% 15,886,876 6,698,513 24,539,309 15,057,049
EBITDA 4-point trend, -67.5% $-30M $-32M $-21M $-18M
Balance Sheet 21
Annual Balance Sheet data for UNCY
Metric Trend 2025202420232022
Cash & Equivalents 4-point trend, +6317.1% $29M $26M $10M $455.0K
Short-term Investments $12M · · ·
Inventory · · · $2M
Prepaid Expense 4-point trend, +251.4% $8M $5M $4M $2M
Current Assets 4-point trend, +1751.8% $49M $31M $13M $3M
PP&E (Net) 4-point trend, +200.0% $66.0K $75.0K $26.0K $22.0K
PP&E (Gross) 4-point trend, +375.9% $138.0K $114.0K $42.0K $29.0K
Accum. Depreciation 4-point trend, +928.6% $72.0K $39.0K $16.0K $7.0K
Total Assets 4-point trend, +1643.6% $49M $32M $14M $3M
Accounts Payable 4-point trend, -57.1% $383.0K $1M $839.0K $892.0K
Accrued Liabilities 4-point trend, -31.9% $2M $4M $3M $2M
Current Liabilities 4-point trend, +476.7% $19M $24M $18M $3M
Capital Leases 2-point trend, -74.9% · $117.0K $466.0K ·
Total Liabilities 4-point trend, +476.7% $19M $24M $18M $3M
Common Stock 4-point trend, +46.7% $22.0K $11.0K $35.0K $15.0K
Paid-in Capital 4-point trend, +371.4% $158M $109M $61M $34M
Retained Earnings 4-point trend, -276.0% $-128M $-101M $-65M $-34M
AOCI $-1.0K · · ·
Stockholders' Equity 4-point trend, +6580.0% $30M $7M $-4M $-466.0K
Liabilities + Equity 4-point trend, +1643.6% $49M $32M $14M $3M
Shares Outstanding 4-point trend, +45.2% 22,114,245 11,384,236 34,756,049 15,231,655
Cash Flow 11
Annual Cash Flow data for UNCY
Metric Trend 2025202420232022
D&A · · · $428.0K
Stock-based Comp 4-point trend, +152.2% $3M $2M $2M $1M
Other Non-cash · · · $932.0K
Operating Cash Flow 4-point trend, -100.1% $-31M $-29M $-18M $-16M
CapEx 4-point trend, +1100.0% $24.0K $72.0K $12.0K $2.0K
Investing Cash Flow 4-point trend, -604650.0% $-12M $-72.0K $-12.0K $-2.0K
Stock Issued · · · $11.0K
Dividends Paid · $1M · ·
Financing Cash Flow 4-point trend, +9965.8% $46M $45M $28M $-471.0K
Net Change in Cash · · · $-16M
Free Cash Flow 4-point trend, -100.2% $-31M $-29M $-18M $-16M
Profitability 5
Annual Profitability data for UNCY
Metric Trend 2025202420232022
Operating Margin 2-point trend, -62.1% · · -3077.6% -1898.2%
Net Margin 2-point trend, -138.3% · · -4525.0% -1898.8%
EBITDA Margin 2-point trend, -66.1% · · -3077.6% -1853.2%
ROA 4-point trend, +60.8% -65.7% -160.2% -359.1% -167.5%
ROE 4-point trend, +86.9% -113.9% 359.8% 16290.1% -868.2%
Liquidity & Solvency 3
Annual Liquidity & Solvency data for UNCY
Metric Trend 2025202420232022
Current Ratio 4-point trend, +221.1% 2.6 1.3 0.8 0.8
Quick Ratio 4-point trend, +1472.3% 2.2 1.1 0.6 0.1
Interest Coverage 2-point trend, +91.6% · · -253.3 -3008.7
Efficiency 1
Annual Efficiency data for UNCY
Metric Trend 2025202420232022
Asset Turnover 2-point trend, -10.0% · · 0.1 0.1
Per Share 5
Annual Per Share data for UNCY
Metric Trend 2025202420232022
Book Value / Share 4-point trend, +4562.4% $1.37 $0.07 $-0.11 $-0.03
Revenue / Share 2-point trend, -56.5% · · $0.03 $0.06
Cash Flow / Share 4-point trend, -89.6% $-1.97 $-0.43 $-0.74 $-1.04
Cash / Share 4-point trend, +4315.7% $1.32 $0.23 $0.28 $0.03
EPS (TTM) 4-point trend, -39.2% $-1.67 $-5.65 $-1.28 $-1.20
Growth Rates 1
Annual Growth Rates data for UNCY
Metric Trend 2025202420232022
Revenue YoY · · -29.0% ·
Valuation (TTM) 13
Annual Valuation (TTM) data for UNCY
Metric Trend 2025202420232022
Revenue TTM 2-point trend, -29.0% · · $675.0K $951.0K
Net Income TTM 4-point trend, -47.1% $-27M $-37M $-31M $-18M
Market Cap 4-point trend, +55.1% $128M $904M $302M $82M
P/E 4-point trend, +23.2% -3.5 -1.4 -6.8 -4.5
P/S 2-point trend, +416.8% · · 446.9 86.5
P/B 4-point trend, +102.4% 4.2 121.6 -79.2 -176.5
P / Tangible Book 2-point trend, -96.5% 4.2 121.6 · ·
P / Cash Flow 4-point trend, +22.5% -4.1 -31.6 -16.5 -5.3
P / FCF 4-point trend, +22.5% -4.1 -31.6 -16.5 -5.3
Dividend Yield · 0.12% · ·
Earnings Yield 4-point trend, -30.2% -28.9% -71.2% -14.8% -22.2%
Payout Ratio 2-point trend, -1.0% · -3.0% -2.9% ·
Annual Payout · $1M · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $675.0K$951.0K
Operating Margin % -3077.6%-1898.2%
Net Income $-27M$-37M$-31M$-18M$-10M
Diluted EPS $-1.67$-5.65$-1.28$-1.20$-0.86
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 2.61.30.80.88.7
Quick Ratio 2.21.10.60.17.9
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-31M$-29M$-18M$-16M

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Institutional owners (13F) 90 filers · $54.1M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
41 (+18 vs prior Q) 7 (+5 vs prior Q) 21 (+9 vs prior Q) 17 (+6 vs prior Q) +1.3M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Nantahala Capital Management, LLC $6,572,786 1,401,447 12.16% Shares
VANGUARD CAPITAL MANAGEMENT LLC $5,025,246 1,071,481 9.29% Shares
Octagon Capital Advisors LP $4,690,000 1,000,000 8.67% Shares
DIADEMA PARTNERS LP $3,717,294 792,600 6.87% Call option
Vivo Capital, LLC $2,579,500 550,000 4.77% Shares
Logos Global Management LP $2,221,010 473,563 4.11% Shares
GEODE CAPITAL MANAGEMENT, LLC $2,214,737 472,056 4.10% Shares
STATE STREET CORP $2,111,260 450,162 3.90% Shares
Caption Management, LLC $1,969,800 420,000 3.64% Call option
Diametric Capital, LP $1,754,679 374,132 3.25% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,570,212 334,800 2.90% Call option
J. Goldman & Co LP $1,535,248 327,345 2.84% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,476,412 314,800 2.73% Put option
DIADEMA PARTNERS LP $1,424,240 303,676 2.63% Shares
MILLENNIUM MANAGEMENT LLC $1,273,129 271,456 2.35% Shares
Dauntless Investment Group, LLC $1,003,660 214,000 1.86% Shares
CITIGROUP INC $850,034 181,244 1.57% Shares
JANE STREET GROUP, LLC $839,041 178,900 1.55% Put option
VANGUARD PORTFOLIO MANAGEMENT LLC $793,529 169,196 1.47% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $750,583 160,039 1.39% Shares
Jump Financial, LLC $717,570 153,000 1.33% Shares
VANGUARD FIDUCIARY TRUST CO $698,646 148,965 1.29% Shares
CITADEL ADVISORS LLC $692,713 147,700 1.28% Put option
DIMENSIONAL FUND ADVISORS LP $597,952 127,495 1.11% Shares
VANGUARD GROUP INC $583,197 101,074 1.08% Shares
Seven Fleet Capital Management LP $521,136 103,400 0.96% Shares
Caption Management, LLC $515,900 110,000 0.95% Shares
LOS ANGELES CAPITAL MANAGEMENT LLC $445,639 95,019 0.82% Shares
CITADEL ADVISORS LLC $433,825 92,500 0.80% Call option
GOLDMAN SACHS GROUP INC $427,071 91,060 0.79% Shares
Persistent Asset Partners Ltd $363,044 77,408 0.67% Shares
Scientech Research LLC $349,358 74,490 0.65% Shares
UBS Group AG $325,378 69,377 0.60% Shares
CITADEL ADVISORS LLC $286,878 61,168 0.53% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $257,209 54,842 0.48% Shares
CANTOR FITZGERALD, L. P. $234,500 50,000 0.43% Shares
SIMPLEX TRADING, LLC $189,579 40,422 0.35% Shares
JANE STREET GROUP, LLC $138,355 29,500 0.26% Call option
RHUMBLINE ADVISERS $137,353 29,288 0.25% Shares
MORGAN STANLEY $134,021 28,576 0.25% Shares
PRELUDE CAPITAL MANAGEMENT, LLC $130,002 27,719 0.24% Shares
Chicago Partners Investment Group LLC $116,899 21,410 0.22% Shares
Cubist Systematic Strategies, LLC $104,409 23,947 0.19% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $103,929 19,948 0.19% Shares
WELLS FARGO & COMPANY/MN $103,504 22,069 0.19% Shares
ALLIANCEBERNSTEIN L.P. $101,210 21,580 0.19% Shares
JPMORGAN CHASE & CO $78,001 10,130 0.14% Shares
MetLife Investment Management, LLC $72,920 15,548 0.13% Shares
Bank of New York Mellon Corp $70,406 15,012 0.13% Shares
SEI INVESTMENTS CO $69,229 14,761 0.13% Shares
Nuveen, LLC $69,229 14,761 0.13% Shares
BANK OF AMERICA CORP /DE/ $66,035 14,080 0.12% Shares
Persistent Asset Partners Ltd $55,238 491 0.10% Call option
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $52,767 11,251 0.10% Shares
JANE STREET GROUP, LLC $52,401 11,173 0.10% Shares
XTX Topco Ltd $49,714 10,600 0.09% Shares
Invesco Ltd. $45,695 9,743 0.08% Shares
Vanguard Global Advisers, LLC $36,896 7,867 0.07% Shares
BlackRock, Inc. $36,000 7,676 0.07% Shares
Police & Firemen's Retirement System of New Jersey $33,796 7,206 0.06% Shares
NEW YORK STATE COMMON RETIREMENT FUND $30,485 6,500 0.06% Shares
STRS OHIO $22,512 4,800 0.04% Shares
NORTHERN TRUST CORP $17,944 3,826 0.03% Shares
BNP PARIBAS FINANCIAL MARKETS $17,512 3,734 0.03% Shares
BARCLAYS PLC $15,337 3,270 0.03% Shares
GABLES CAPITAL MANAGEMENT INC. $14,070 3,000 0.03% Shares
Legal & General Group Plc $11,092 2,365 0.02% Shares
GROUP ONE TRADING LLC $10,787 2,300 0.02% Shares
Ameritas Investment Partners, Inc. $10,398 2,217 0.02% Shares
Rockefeller Capital Management L.P. $9,849 2,100 0.02% Shares
Russell Investments Group, Ltd. $9,159 1,953 0.02% Shares
Tower Research Capital LLC (TRC) $8,386 1,788 0.02% Shares
Integrated Wealth Concepts LLC $4,690 1,000 0.01% Shares
ROYAL BANK OF CANADA $4,000 792 0.01% Shares
OSAIC HOLDINGS, INC. $2,973 634 0.01% Shares
SBI Securities Co., Ltd. $2,612 557 0.00% Shares
FIDUCIARY FINANCIAL ADVISORS $2,345 500 0.00% Shares
DEUTSCHE BANK AG\ $2,087 445 0.00% Shares
TFC Financial Management, Inc. $1,407 300 0.00% Shares
Larson Financial Group LLC $938 200 0.00% Shares
Sterling Capital Management LLC $633 135 0.00% Shares
HARBOUR INVESTMENTS, INC. $469 100 0.00% Shares
MARSHALL WACE, LLP $450 96 0.00% Shares
FMR LLC $394 84 0.00% Shares
Fortitude Family Office, LLC $352 75 0.00% Shares
Caitong International Asset Management Co., Ltd $244 52 0.00% Shares
PRICE T ROWE ASSOCIATES INC /MD/ $95 20,048 0.00% Shares
Virtu Financial LLC $54 11,610 0.00% Shares
Bogart Wealth, LLC $28 6 0.00% Shares
DANSKE BANK A/S $5 1 0.00% Shares

Company insiders 9 insiders · 4 officers · 6 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Shalabh K. Gupta CEO May 14, 2026 A 2,527,449 0 0 $0
John Townsend CFO May 14, 2026 A 0 0 $0
Douglas Jermasek EVP, Corporate Strategy May 14, 2026 A 175,012 0 0 $0
Pramod Gupta EVP, Pharmaceuticals and BD May 14, 2026 A 41,845 0 0 $0
Sara Kenkare-Mitra Director May 14, 2026 A 0 0 $0
Sandeep Laumas Director May 14, 2026 A 0 0 $0
Gaurav Aggarwal Director Aug. 25, 2025 D 1,789,915 0 0 $0
John L Ryan Director Sept. 5, 2023 A 0 0 $0
Brigitte Schiller Director July 15, 2022 M 26,738 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 14 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
DFAS · Dimensional ETF Trust 0.00% 67,827 NS April 30, 2026 N-PORT
DFSU · Dimensional ETF Trust 0.00% 2,981 NS April 30, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 3,419 NS April 30, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 8,341 NS April 30, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTI · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
IWN · iShares Trust Aug. 17, 2026 Daily
IWO · iShares Trust Aug. 18, 2026 Daily
IWM · iShares Trust Aug. 18, 2026 Daily
IWC · iShares Trust Aug. 18, 2026 Daily