Performance vs S&P 500

03
Tracked Q1 2025–Q2 2026 +68.1%
S&P 500 total return (same window) +37.0%
Excess return +31.1%

Annualized: +51.6% · S&P 500: +28.7%

Approximates a buy-and-hold portfolio built from quarterly SEC 13F snapshots. Excludes cash, short positions, options/derivatives, and non-13(f) securities — reflects the disclosed long-equity book only, not total fund AUM. SEC filing lag is up to 45 days; this is not a real-time-copyable timing.

Priceable coverage: 94.9% · Options excluded: 0.0%

Sector breakdown

04
Healthcare 99.9%
Other/Unmapped 0.1%

Full portfolio 11 positions

05
Type Streak 8Q trend
NAMS NewAmsterdam Pharma Company N.V. - Ordinary Shares $287,738,063 38.34% 8,490,353 $-6,718,726 Down ×1
MPLT MapLight Therapeutics, Inc. - Common Stock $115,634,176 15.41% 3,226,400 $50,041,464
DYN Dyne Therapeutics, Inc. - Common Stock $85,469,766 11.39% 3,848,256 $1,267,048 Down ×2
VOR Vor Biopharma Inc. - Common Stock $75,800,487 10.10% 4,117,354 $2,346,892
GLTO Galecto, Inc. - Common Stock $63,490,410 8.46% 2,441,000 $268,510
REPL Replimune Group, Inc. - Common Stock $31,088,634 4.14% 2,808,368 $9,604,619
CBIO Crescent Biopharma, Inc. - Common Stock $30,201,336 4.02% 1,677,852 $-620,805
AURA Aura Biosciences, Inc. - Common Stock $28,781,803 3.84% 4,053,775 Up ×1
ENGN enGene Holdings Inc. - Common Stock $16,664,330 2.22% 9,632,561 $-48,933,410
BCYC Bicycle Therapeutics plc - American Depositary Shares $14,706,143 1.96% 3,468,430 $-1,387,372
ENGNW enGene Holdings Inc. - Warrants $834,376 0.11% 2,878,148 $-6,447,338

Biggest new bets

09

New positions opened this quarter, largest first.

SecurityValueShares% of portfolio
AURA $28,781,803 4,053,775 3.84%

Top movers (QoQ)

10
SecurityActionShares ΔValue Δ
MPLT Price move only +0 +$50.0M
ENGN Price move only +0 -$48.9M
REPL Price move only +0 +$9.6M
NAMS Trimmed -709K -$6.7M
VOR Price move only +0 +$2.3M
BCYC Price move only +0 -$1.4M
DYN Trimmed -796K +$1.3M
CBIO Price move only +0 -$621K
GLTO Price move only +0 +$269K

1 position hidden — reported move looks larger than the position itself (data completeness check)

Exited positions

11

Includes corporate events (mergers, delistings) — not all exits are sells

Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.

SecurityQuarterShares beforeValue beforePrice since exit
RAPT March 31, 2026 1,833,333 $62,094,989 No longer tracked
ATXS Dec. 31, 2025 4,107,537 $29,902,869 No longer tracked