CBIO Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $14.32
Market Cap (MRQ) $397M
P/E -29.2
EPS $-0.59
Revenue $11M
ROE -90.0%
52W Range $9–$27

CBIO Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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Stock splits 1
Ex-date Split Type
June 16, 2025 1-for-100 Reverse

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$11M
2016-12-31 → 2025-12-31
EPS$-0.59
2019-12-31 → 2024-12-31
Free Cash Flow$-72M
2016-12-31 → 2025-12-31
Net margin-1419.6%
2016-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend CBIO 5Y avg Peer Median Verdict
P/E -29.25Y avg ≈-186.2 ≈-186.2 · ·
P/S 36.45Y avg ≈436476.1 ≈436476.1 144.0 Undervalued
P/B (MRQ) 2.45Y avg ≈235.3 ≈235.3 3.0 Fair value
Price / FCF (TTM) -5.45Y avg ≈-195.4 ≈-195.4 · ·
Price / Cash Flow (TTM) -5.55Y avg ≈-195.6 ≈-195.6 · ·
Price / Tangible Book 1.95Y avg ≈218.3 ≈218.3 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Dividends Yield, payout ratio, dividend history, 5Y CAGR

13
Annualized Payout≈$96.00Paid quarterly
Ex-dateAmountCurrencyYield
Jan 13, 2023$24.00USD≈55.3%
Sep 21, 2022$143.00USD≈223.4%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -0.05%
Next Report Nov 04, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 $-0.74 $-0.81 8.7%
March 31, 2026 $-0.70 $-0.97 27.5%
Dec. 31, 2025 $-0.54 $-2.57 79.0%
Sept. 30, 2025 $-1.27 $-2.02 37.2%
June 30, 2025 $-4.93 $-1.80 -174.2%
March 31, 2025 $-4.00 $-5.10 21.6%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $11M·$10.0K$75.0K$1M$10M···$18.5K$20M$15M
R&D Expense $138M$14M$20M$28M$47M$45M$47M$40M$24M$23M$25M$20M
SG&A Expense $25M$18M$19M$19M$17M$17M$14M$11M$10M$9M$8M$7M
Operating Expenses $163M$40M$39M$47M$65M$62M$61M$52M$34M$32M$33M$26M
Operating Income $-153M$-40M$-39M$-47M$-63M$-52M$-61M$-52M$-34M$-32M$-13M$-11M
Other Non-op ·$2M$2M·····$651.2K$103.6K$15.3K$18.2K
Pretax Income $-152M···········
Income Tax $2M···········
Net Income $-154M$-38M$-37M$-47M$-63M$-51M$-58M$-48M$-33M$-32M$-13M$-11M
EPS (Basic) ·$-0.59$-0.58$-0.89$-1.23$-1.12$-1.34····$-0.60
EPS (Diluted) ·$-0.59$-0.58$-0.89$-1.23$-1.12$-1.34····$-0.60
Shares (Basic) ·64,477,24963,342,46552,531,17351,453,20445,721,13943,254,782····18,452,252
Shares (Diluted) ·64,477,24963,342,46552,531,17351,453,20445,721,13943,254,782····18,452,252
EBITDA $-153M$-40M$-39M$-47M$-63M$-52M$-61M$-52M$-34M$-32M$-13M$-11M
Balance Sheet 21
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $213M$35M$42M$48M$90M$137M$158M$210M$124M$40M$47M$55M
Receivables $18M$0··········
Prepaid Expense $5M$38.0K$2M$3M$533.8K$1M$4M$2M$3M$478.5K$441.8K$916.2K
Other Current Assets $5M$38.0K··········
Current Assets $237M$35M$44M$51M$91M$138M$163M$212M$127M$41M$47M$56M
PP&E (Net) $846.0K$0·$242.4K$368.8K$620.7K$822.9K$957.2K$1M$1M$521.4K$452.3K
PP&E (Gross) ···$3M$3M$3M$3M$3M$2M$2M$1M$1M
Accum. Depreciation ···$2M$2M$2M$2M$2M$1M$1M$902.1K$905.5K
Other Non-current Assets $1M$813.0K··········
Total Assets $240M$36M$45M$52M$94M$143M$168M$215M$129M$42M$48M$57M
Accounts Payable ·$329.3K$868.1K$970.2K$2M$2M$1M$3M$3M$2M$564.2K$874.0K
Accrued Liabilities $16M$2M$5M$7M$9M$9M$9M$6M$4M$3M$6M$5M
Current Liabilities $36M$10M$7M$9M$12M$12M$11M$9M$8M$6M$8M$6M
Capital Leases $1M$0$66.8K·$918.6K$2M$3M·····
Total Liabilities $37M$47M$7M$9M$13M$15M$14M$9M$9M$7M$8M$6M
Common Stock $28.0K$1.0K$64.4K$54.4K$52.3K$49.0K$43.5K$43.2K$34.4K$23.2K$19.0K$18.9K
Paid-in Capital $371M$2M$495M$462M$454M$438M$413M$406M$272M$154M$128M$125M
Retained Earnings $-172M$-18M$-456M$-420M$-373M$-309M$-258M$-201M$-152M$-119M$-87M$-74M
Stockholders' Equity $203M$-15M$38M$43M$82M$128M$154M$205M$120M$35M$40M$51M
Liabilities + Equity $240M$36M$45M$52M$94M$143M$168M$215M$129M$42M$48M$57M
Shares Outstanding 27,556,7671,018,60464,393,74454,377,79852,313,89449,017,62243,466,93343,160,75134,359,79923,250,02319,050,20418,939,838
Cash Flow 11
Metric Trend 202520242023202220212020201920182017201620152014
Stock-based Comp $13M$5M$4M$4M$6M$7M$6M$5M$4M$3M$2M$2M
Deferred Tax $0···········
Restructuring ·$7M··········
Operating Cash Flow $-72M$-31M$-35M$-46M$-57M$-39M$-52M$-43M$-30M$-30M$-8M$-4M
CapEx $919.0K$10.0K$21.4K$84.2K$14.9K$68.5K$144.9K$125.6K$294.1K$704.2K$268.6K$212.6K
Investing Cash Flow $-73M$20.0K$-21.4K$-84.2K$-14.9K$-68.5K$-144.9K$-125.6K$-294.1K$-704.2K$-268.6K·
Stock Issued $0·$29M$4M$11M$18M·$128M$114M$24M·$57M
Net Stock Activity $0·$29M$4M$11M$18M·$128M$114M$24M·$57M
Financing Cash Flow $323M$5.4K$29M$4M$11M$18M$412.9K$129M$114M$24M$114.1K·
Net Change in Cash $179M$-31M$-6M$-42M$-47M$-21M$-52M$86M$84M$-7M$-8M$53M
Free Cash Flow $-72M$-31M$-35M$-47M$-58M$-39M$-52M$-43M$-30M$-30M$-9M$-4M
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin -1407.5%·-392752.9%-63204.4%-5470.7%-506.8%···-172505.3%-63.7%-74.1%
Net Margin -1419.6%·-368994.2%-62251.7%-5469.0%-502.1%···-171945.1%-63.6%-74.0%
Pretax Margin -1401.2%···········
EBITDA Margin -1407.5%·-392752.9%-63204.4%-5470.7%-506.8%···-172505.3%-63.7%-74.1%
ROA -111.6%-134.3%-76.0%-63.9%-53.5%-32.8%-30.2%-28.1%-38.9%-70.0%-24.2%-35.6%
ROE -90.0%-1888.5%-86.9%-102.6%-71.2%-38.3%-36.0%-22.8%-42.9%-84.0%-28.0%-41.4%
ROIC -76.2%···········
Liquidity & Solvency 2
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 6.61.96.45.77.711.114.824.215.66.46.18.7
Quick Ratio 6.41.96.15.47.611.014.424.015.26.36.08.5
Efficiency 2
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.1·0.00.00.00.1···0.00.40.5
Receivables Turnover 1.2···········
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $7.37$0.08$0.60$0.79$1.56$2.62$3.55$4.76$3.48$1.52$2.12$2.68
Revenue / Share ··$0.00$0.00$0.02······$0.81
Cash Flow / Share ·$-0.48$-0.55$-0.88$-1.12······$-0.23
Cash / Share $7.74$0.17$0.65$0.88$1.73$2.80$3.64$4.86$3.61$1.72$2.46$2.91
EPS (TTM) $-0.49$-0.59$-0.58$-0.89$-1.23$-1.12$-1.34$-0.75$-0.75$-0.75$-0.71$-0.60
Growth Rates 3
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY ··-86.7%-93.5%-88.6%·······
Revenue CAGR 3Y 424.9%·-90.0%·········
Revenue CAGR 5Y 1.3%···········
Valuation (TTM) 10
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $11M·$10.0K$75.0K$1M$10M···$18.5K$20M$15M
Net Income TTM $-154M$-38M$-37M$-47M$-63M$-51M$-58M$-48M$-33M$-32M$-13M$-11M
Market Cap $327M$1.61B$15.20B$16.48B$7.53B$18.43B$22.99B$40.87B$57.69B$14.18B$10.90B$13.64B
P/E -24.2-42.4-406.9-340.4-117.1-335.7-394.8-1262.7-2238.7-813.3-805.6-1200.0
P/S 30.1·1519692.4219686.36495.41813.5···766622.4542.9907.5
P/B 1.6303.4395.6383.892.3143.7149.1198.9481.9401.8269.2268.4
P / Tangible Book 1.6·395.6383.892.3143.7······
P / Cash Flow -4.6-51.8-435.7-354.7-131.0-469.7-442.3-943.3-1938.0-477.0-1322.1-3185.0
P / FCF -4.5-51.8-435.4-354.0-131.0-468.8-441.1-940.5-1919.0-466.0-1280.4-3034.3
Earnings Yield -4.1%-2.4%-0.25%-0.29%-0.85%-0.30%-0.25%-0.08%-0.04%-0.12%-0.12%-0.08%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $11M · $10.0K $75.0K $1M
Operating Margin % -1407.5% · -392752.9% -63204.4% -5470.7%
Net Income $-154M $-38M $-37M $-47M $-63M
Diluted EPS · $-0.59 $-0.58 $-0.89 $-1.23

Institutional owners (13F) 82 filers · $526.1M total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 82
Value held $526.1M
New positions 32
Exited positions 12
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
32 (+15 vs prior Q) 12 (+2 vs prior Q) 17 (0 vs prior Q) 14 (+6 vs prior Q) +4.0M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
FMR LLC $74,403,252 4,133,514 14.14% Shares
BVF INC/IL $49,477,734 2,748,763 9.40% Shares
Fairmount Funds Management LLC $49,461,588 2,747,866 9.40% Shares
Venrock Adviser, LLC $38,404,368 2,133,576 7.30% Shares
Logos Global Management LP $34,200,000 1,900,000 6.50% Shares
FCPM III SERVICES B.V. $30,201,336 1,677,852 5.74% Shares
Balyasny Asset Management L.P. $29,932,506 1,662,917 5.69% Shares
Vestal Point Capital, LP $29,340,000 1,630,000 5.58% Shares
Opaleye Management Inc. $23,748,318 1,319,351 4.51% Shares
BlackRock, Inc. $22,891,716 1,271,762 4.35% Shares
TANG CAPITAL MANAGEMENT LLC $20,880,000 1,160,000 3.97% Shares
VANGUARD CAPITAL MANAGEMENT LLC $13,819,590 767,755 2.63% Shares
MILLENNIUM MANAGEMENT LLC $7,269,462 403,859 1.38% Shares
GEODE CAPITAL MANAGEMENT, LLC $6,923,843 384,576 1.32% Shares
JENNISON ASSOCIATES LLC $6,813,126 378,507 1.30% Shares
RTW INVESTMENTS, LP $6,711,408 372,856 1.28% Shares
NEXTBio Capital Management LP $6,711,408 372,856 1.28% Shares
VANGUARD GROUP INC $6,612,021 557,506 1.26% Shares
Remedium Capital Partners, LLC $6,502,500 361,250 1.24% Shares
STATE STREET CORP $5,680,566 315,587 1.08% Shares
AMERIPRISE FINANCIAL INC $5,446,224 302,568 1.04% Shares
Point72 Asset Management, L.P. $5,400,000 300,000 1.03% Shares
MARSHALL WACE, LLP $3,857,400 214,300 0.73% Shares
PERCEPTIVE ADVISORS LLC $3,724,956 206,942 0.71% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $3,398,454 188,803 0.65% Shares
TWO SIGMA INVESTMENTS, LP $3,363,732 186,874 0.64% Shares
STEMPOINT CAPITAL LP $3,282,876 182,382 0.62% Shares
UBS Group AG $3,153,276 175,182 0.60% Shares
NORTHERN TRUST CORP $2,498,004 138,778 0.47% Shares
Exome Asset Management LLC $2,299,842 127,769 0.44% Shares
SECTORAL ASSET MANAGEMENT INC $2,183,400 121,300 0.42% Shares
Woodline Partners LP $1,700,784 94,488 0.32% Shares
VANGUARD FIDUCIARY TRUST CO $1,354,050 75,225 0.26% Shares
Burkehill Global Management, LP $1,332,000 74,000 0.25% Shares
Blackstone Inc. $1,127,646 62,647 0.21% Shares
SILVERARC CAPITAL MANAGEMENT, LLC $1,063,872 59,104 0.20% Shares
Y-Intercept (Hong Kong) Ltd $914,832 50,824 0.17% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $904,644 50,258 0.17% Shares
Nuveen, LLC $857,322 47,629 0.16% Shares
Bank of New York Mellon Corp $824,004 45,778 0.16% Shares
Stonepine Capital Management, LLC $720,000 40,000 0.14% Shares
BANK OF AMERICA CORP /DE/ $464,778 25,821 0.09% Shares
RHUMBLINE ADVISERS $458,766 25,487 0.09% Shares
MOORE CAPITAL MANAGEMENT, LP $450,000 25,000 0.09% Shares
Squarepoint Ops LLC $434,988 24,166 0.08% Shares
AMERICAN CENTURY COMPANIES INC $410,490 22,805 0.08% Shares
TWO SIGMA ADVISERS, LP $385,450 32,500 0.07% Shares
WELLS FARGO & COMPANY/MN $354,600 19,700 0.07% Shares
ADAR1 Capital Management, LLC $328,950 18,275 0.06% Shares
Virtus Investment Advisers, LLC $328,644 18,258 0.06% Shares

Show all 82 institutional owners →

Activists & 5%+ owners 4 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Fairmount Funds Management LLC, Fairmount Healthcare Fund II L.P., Peter Harwin, Tomas Kiselak ×3 filings July 20, 2026 16.52% Amendment Passive investment SEC
Adage Capital Management, L.P., Robert Atchinson, Phillip Gross ×2 filings June 20, 2025 0.37% Amendment · SEC
May 8, 2024 · Initial filing · SEC
New Enterprise Associates 10, Limited Partnership, NEA Partners 10, Limited Partnership, New Enterprise Associates 13, L.P., NEA Partners 13, L.P., NEA 13 GP, LTD, Anthony A. Florence, Jr, Mohamad H. Makhzoumi, Scott D. Sandell ×4 filings Feb. 29, 2024 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 34 insiders · 16 officers · 18 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Joshua T Brumm Chief Executive Officer Sept. 18, 2026 S 271,765 0 3 $-920,842
Harout Semerjian Chief Executive Officer Jan. 12, 2024 A 25,000 0 0 $0
Richard William Scalzo Chief Financial Officer Sept. 16, 2026 S 19,730 0 2 $-30,172
Brian M. Hahn SVP Finance, CFO June 18, 2024 P 70,643 0 0 $0
Jonathan Mcneill President and COO Sept. 18, 2026 S 134,588 0 3 $-446,912
Jan Pinkas Chief Scientific Officer Sept. 16, 2026 S 21,581 0 2 $-34,949
Barbara Harlin Bispham General Counsel and Corporate Secretary. Sept. 16, 2026 S 18,710 0 2 $-33,010
Ellie Eunkyung Im Chief Medical Officer Sept. 16, 2026 S 21,446 0 2 $-33,082
Ryan Lynch Treasurer, Senior Vice President of Finance and Chief Accounting Officer. Sept. 16, 2026 S 13,631 0 2 $-12,661
Christopher Grant Doughty Chief Business Officer Dec. 15, 2025 A 62,194 0 0 $0
Edwin Rock Chief Medical Officer June 21, 2024 P 680,403 0 0 $0
Bruce S Johnson SVP & Chief Commercial Officer Jan. 12, 2024 A 138,980 0 0 $0
Chinmaya Rath SVP and Chief Business Officer Jan. 12, 2024 A · 0 0 $0
Armand Girard SVP, Chief Business Officer Nov. 11, 2022 P 29,161 0 0 $0
John L. Magnani SVP of Research, CSO Nov. 11, 2022 P 366,078 0 0 $0
Helen M. Thackray SVP Clinical Development, CMO Jan. 20, 2021 A 183,115 0 0 $0
Alexandra Balcom Director June 2, 2026 A · 0 0 $0
Susan Moran Director June 2, 2026 A · 0 0 $0
Jonathan Violin Director June 2, 2026 A · 0 0 $0
David Charles Lubner Director June 2, 2026 A · 0 0 $0
Rachel K. King Director May 1, 2024 A 515,194 0 0 $0
Scott Koenig Director May 1, 2024 A 36,750 0 0 $0
Scott Thomas Jackson Director May 1, 2024 A 5,250 0 0 $0
Mark Alan Goldberg Director May 1, 2024 A 24,828 0 0 $0
Timothy R Pearson Director May 1, 2024 A 24,650 0 0 $0
Patricia S Andrews Director May 1, 2024 A 58,608 0 0 $0
JUNIUS DANIEL M Director May 1, 2024 A 98,459 0 0 $0
James M Barrett Director May 18, 2018 A 4,995,664 0 0 $0
John J. Baldwin Director June 29, 2016 M 1,210 0 0 $0
Franklin H Top JR Director May 17, 2016 A 12,294 0 0 $0
Michael A Henos Director July 15, 2015 A 469,454 0 0 $0
William M. Gust Director Jan. 15, 2014 C 409,947 0 0 $0
Scott D. Sandell 10% owner Jan. 26, 2023 S 2,237,196 0 0 $0
Peter J Barris 10% owner May 10, 2018 X 4,995,664 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 10 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IWC · iShares Trust 0.10% 72,879 SH Sept. 11, 2026 Daily
IWO · iShares Trust 0.03% 202,796 SH Sept. 11, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.02% 23,282 SH Aug. 19, 2026 Daily
IWM · iShares Trust 0.01% 544,047 SH Sept. 11, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 124,281 SH Aug. 19, 2026 Daily
RSSL · Global X Funds 0.01% 10,277 NS July 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.00% 83,801 SH Aug. 19, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 661,946 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 1,832 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.00% 39,408 SH Aug. 19, 2026 Daily

CBIO Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 15 analysts BUY
Median target $28.00 +95.5%
6 40.0% Strong Buy
7 46.7% Buy
2 13.3% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

5 analysts · 2026-09-30

Mean target $30.60 +113.7%

← Below all targets Current price $14.32
Low$27.00 Mean$30.60 High$35.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CBIO $327M -24.2 -86.7% -1419.6% -90.0% ·
ALT $400M -3.6 105.0% -214861.0% -45.6% ·
ALLO $314M -1.6 -76.8% · -59.9% ·
MPLT $773M -0.9 · · -151.1% ·
MNPR · · · · · ·
NGNE $319M -4.9 · · -33.6% ·
ZURA · · · · · ·
CAPR $1.66B -12.8 -11.6% · -51.1% ·
PROK · · 1075.0% -7725.2% 6.9% ·
PBYI $300M 9.8 -0.91% 13.6% 26.5% ·
RGNX $733M -3.8 104.5% -113.8% -122.5% ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Jul 30, 2026