CBIO Crescent Biopharma, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$18.40
Price · May 20, 2026
Fundamentals as of Apr 29, 2026

CBIO Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$18.40
Market Cap
$327M
P/E (TTM)
-24.2
EPS (TTM)
$-0.59
Revenue (TTM)
$11M
Div Yield
ROE
-90.0%
Debt/Equity
52W Range
$9 – $27

CBIO Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $11M
6-point trend, +58516.2%
2016-12-31 2025-12-31
EPS $-0.59
6-point trend, +56.0%
2019-12-31 2024-12-31
Free Cash Flow $-72M
10-point trend, -138.0%
2016-12-31 2025-12-31
Margins -1419.6%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
CBIO
Peer Median
P/E (TTM)
5-point trend, +79.3%
-24.2
19.2
P/S (TTM)
5-point trend, -98.3%
30.1
31.6
P/B
5-point trend, -98.3%
1.6
2.4
Price / FCF
5-point trend, +96.6%
-4.5

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
CBIO
Peer Median
Operating Margin
5-point trend, -177.7%
-1407.5%
Net Profit Margin
5-point trend, -182.7%
-1419.6%
-94.7%
ROA
5-point trend, -108.7%
-111.6%
-39.0%
ROE
5-point trend, -26.3%
-90.0%
-50.4%
ROIC
-76.2%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
CBIO
Peer Median
Current Ratio
5-point trend, -14.6%
6.6
5.4
Quick Ratio
5-point trend, -16.0%
6.4

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
CBIO
Peer Median
Revenue YoY
5-point trend, +6.7%
-86.7%
Revenue CAGR 3Y
5-point trend, +6.7%
424.9%
Revenue CAGR 5Y
5-point trend, +6.7%
1.3%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
CBIO
Peer Median
EPS (Diluted)
5-point trend, +47.3%
$-0.59

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
CBIO
Peer Median

Dividends Yield, payout ratio, dividend history, 5Y CAGR

Dividend Yield
Payout Ratio
5Y Div CAGR
Ex-dateAmount
Jan. 13, 2023$24.0000
Sept. 21, 2022$143.0000

CBIO Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 15 analysts
  • Strong Buy 6 40.0%
  • Buy 8 53.3%
  • Hold 1 6.7%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

7 analysts · 2026-05-20
Median target $30.00 +63.0%
Mean target $30.29 +64.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.20%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.70 $-0.97 0.27%
Dec. 31, 2025 $-0.54 $-2.57 2.0%
Sept. 30, 2025 $-1.27 $-2.02 0.75%
June 30, 2025 $-4.93 $-1.80 -3.1%
March 31, 2025 $-4.00 $-5.10 1.1%

Peer Comparison Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CBIO $327M -24.2 -86.7% -1419.6% -90.0%
ALT $400M -3.6 105.0% -214861.0% -45.6%
RIGL $784M 2.2 64.1% 124.7% 155.1%
STRO $99M -0.5 65.2% -186.5% 232.2%
XOMA $315M 18.2 83.1% 60.8% 43.5%
TECX $391M -5.2 -27.7%
PRME $626M -2.6 55.3% -4342.4% -221.4%
IMMX $277M -5.9 -59.8%
PROK 1075.0% -7725.2% 6.9%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for CBIO
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 8-point trend, -27.8% $11M · $10.0K $75.0K $1M $10M · · · $18.5K $20M $15M
R&D Expense 12-point trend, +605.6% $138M $14M $20M $28M $47M $45M $47M $40M $24M $23M $25M $20M
SG&A Expense 12-point trend, +284.9% $25M $18M $19M $19M $17M $17M $14M $11M $10M $9M $8M $7M
Operating Expenses 12-point trend, +524.7% $163M $40M $39M $47M $65M $62M $61M $52M $34M $32M $33M $26M
Operating Income 12-point trend, -1270.1% $-153M $-40M $-39M $-47M $-63M $-52M $-61M $-52M $-34M $-32M $-13M $-11M
Other Non-op 6-point trend, +11742.7% · $2M $2M · · · · · $651.2K $103.6K $15.3K $18.2K
Pretax Income $-152M · · · · · · · · · · ·
Income Tax $2M · · · · · · · · · · ·
Net Income 12-point trend, -1284.2% $-154M $-38M $-37M $-47M $-63M $-51M $-58M $-48M $-33M $-32M $-13M $-11M
EPS (Basic) 7-point trend, +1.7% · $-0.59 $-0.58 $-0.89 $-1.23 $-1.12 $-1.34 · · · · $-0.60
EPS (Diluted) 7-point trend, +1.7% · $-0.59 $-0.58 $-0.89 $-1.23 $-1.12 $-1.34 · · · · $-0.60
Shares (Basic) 7-point trend, +249.4% · 64,477,249 63,342,465 52,531,173 51,453,204 45,721,139 43,254,782 · · · · 18,452,252
Shares (Diluted) 7-point trend, +249.4% · 64,477,249 63,342,465 52,531,173 51,453,204 45,721,139 43,254,782 · · · · 18,452,252
EBITDA 12-point trend, -1270.1% $-153M $-40M $-39M $-47M $-63M $-52M $-61M $-52M $-34M $-32M $-13M $-11M
Balance Sheet 21
Annual Balance Sheet data for CBIO
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +286.2% $213M $35M $42M $48M $90M $137M $158M $210M $124M $40M $47M $55M
Receivables 2-point trend, +18000000.00 $18M $0 · · · · · · · · · ·
Prepaid Expense 12-point trend, +496.2% $5M $38.0K $2M $3M $533.8K $1M $4M $2M $3M $478.5K $441.8K $916.2K
Other Current Assets 2-point trend, +14276.3% $5M $38.0K · · · · · · · · · ·
Current Assets 12-point trend, +321.7% $237M $35M $44M $51M $91M $138M $163M $212M $127M $41M $47M $56M
PP&E (Net) 11-point trend, +87.1% $846.0K $0 · $242.4K $368.8K $620.7K $822.9K $957.2K $1M $1M $521.4K $452.3K
PP&E (Gross) 9-point trend, +93.6% · · · $3M $3M $3M $3M $3M $2M $2M $1M $1M
Accum. Depreciation 9-point trend, +163.6% · · · $2M $2M $2M $2M $2M $1M $1M $902.1K $905.5K
Other Non-current Assets 2-point trend, +49.6% $1M $813.0K · · · · · · · · · ·
Total Assets 12-point trend, +319.6% $240M $36M $45M $52M $94M $143M $168M $215M $129M $42M $48M $57M
Accounts Payable 11-point trend, -62.3% · $329.3K $868.1K $970.2K $2M $2M $1M $3M $3M $2M $564.2K $874.0K
Accrued Liabilities 12-point trend, +245.1% $16M $2M $5M $7M $9M $9M $9M $6M $4M $3M $6M $5M
Current Liabilities 12-point trend, +458.3% $36M $10M $7M $9M $12M $12M $11M $9M $8M $6M $8M $6M
Capital Leases 6-point trend, -57.1% $1M $0 $66.8K · $918.6K $2M $3M · · · · ·
Total Liabilities 12-point trend, +477.1% $37M $47M $7M $9M $13M $15M $14M $9M $9M $7M $8M $6M
Common Stock 12-point trend, +47.8% $28.0K $1.0K $64.4K $54.4K $52.3K $49.0K $43.5K $43.2K $34.4K $23.2K $19.0K $18.9K
Paid-in Capital 12-point trend, +196.2% $371M $2M $495M $462M $454M $438M $413M $406M $272M $154M $128M $125M
Retained Earnings 12-point trend, -130.9% $-172M $-18M $-456M $-420M $-373M $-309M $-258M $-201M $-152M $-119M $-87M $-74M
Stockholders' Equity 12-point trend, +299.6% $203M $-15M $38M $43M $82M $128M $154M $205M $120M $35M $40M $51M
Liabilities + Equity 12-point trend, +319.6% $240M $36M $45M $52M $94M $143M $168M $215M $129M $42M $48M $57M
Shares Outstanding 12-point trend, +45.5% 27,556,767 1,018,604 64,393,744 54,377,798 52,313,894 49,017,622 43,466,933 43,160,751 34,359,799 23,250,023 19,050,204 18,939,838
Cash Flow 11
Annual Cash Flow data for CBIO
Metric Trend 202520242023202220212020201920182017201620152014
Stock-based Comp 12-point trend, +713.4% $13M $5M $4M $4M $6M $7M $6M $5M $4M $3M $2M $2M
Deferred Tax $0 · · · · · · · · · · ·
Restructuring · $7M · · · · · · · · · ·
Operating Cash Flow 12-point trend, -1570.7% $-72M $-31M $-35M $-46M $-57M $-39M $-52M $-43M $-30M $-30M $-8M $-4M
CapEx 12-point trend, +332.3% $919.0K $10.0K $21.4K $84.2K $14.9K $68.5K $144.9K $125.6K $294.1K $704.2K $268.6K $212.6K
Investing Cash Flow 11-point trend, -27048.4% $-73M $20.0K $-21.4K $-84.2K $-14.9K $-68.5K $-144.9K $-125.6K $-294.1K $-704.2K $-268.6K ·
Stock Issued 9-point trend, -100.0% $0 · $29M $4M $11M $18M · $128M $114M $24M · $57M
Net Stock Activity 9-point trend, -100.0% $0 · $29M $4M $11M $18M · $128M $114M $24M · $57M
Financing Cash Flow 11-point trend, +282918.9% $323M $5.4K $29M $4M $11M $18M $412.9K $129M $114M $24M $114.1K ·
Net Change in Cash 12-point trend, +237.6% $179M $-31M $-6M $-42M $-47M $-21M $-52M $86M $84M $-7M $-8M $53M
Free Cash Flow 12-point trend, -1512.1% $-72M $-31M $-35M $-47M $-58M $-39M $-52M $-43M $-30M $-30M $-9M $-4M
Profitability 7
Annual Profitability data for CBIO
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 8-point trend, -1798.7% -1407.5% · -392752.9% -63204.4% -5470.7% -506.8% · · · -172505.3% -63.7% -74.1%
Net Margin 8-point trend, -1818.1% -1419.6% · -368994.2% -62251.7% -5469.0% -502.1% · · · -171945.1% -63.6% -74.0%
Pretax Margin -1401.2% · · · · · · · · · · ·
EBITDA Margin 8-point trend, -1798.7% -1407.5% · -392752.9% -63204.4% -5470.7% -506.8% · · · -172505.3% -63.7% -74.1%
ROA 12-point trend, -213.8% -111.6% -134.3% -76.0% -63.9% -53.5% -32.8% -30.2% -28.1% -38.9% -70.0% -24.2% -35.6%
ROE 12-point trend, -117.2% -90.0% -1888.5% -86.9% -102.6% -71.2% -38.3% -36.0% -22.8% -42.9% -84.0% -28.0% -41.4%
ROIC -76.2% · · · · · · · · · · ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for CBIO
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 12-point trend, -24.5% 6.6 1.9 6.4 5.7 7.7 11.1 14.8 24.2 15.6 6.4 6.1 8.7
Quick Ratio 12-point trend, -25.0% 6.4 1.9 6.1 5.4 7.6 11.0 14.4 24.0 15.2 6.3 6.0 8.5
Efficiency 2
Annual Efficiency data for CBIO
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 8-point trend, -83.6% 0.1 · 0.0 0.0 0.0 0.1 · · · 0.0 0.4 0.5
Receivables Turnover 1.2 · · · · · · · · · · ·
Per Share 5
Annual Per Share data for CBIO
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 12-point trend, +174.6% $7.37 $0.08 $0.60 $0.79 $1.56 $2.62 $3.55 $4.76 $3.48 $1.52 $2.12 $2.68
Revenue / Share 4-point trend, -100.0% · · $0.00 $0.00 $0.02 · · · · · · $0.81
Cash Flow / Share 5-point trend, -107.9% · $-0.48 $-0.55 $-0.88 $-1.12 · · · · · · $-0.23
Cash / Share 12-point trend, +165.5% $7.74 $0.17 $0.65 $0.88 $1.73 $2.80 $3.64 $4.86 $3.61 $1.72 $2.46 $2.91
EPS (TTM) 12-point trend, +18.3% $-0.49 $-0.59 $-0.58 $-0.89 $-1.23 $-1.12 $-1.34 $-0.75 $-0.75 $-0.75 $-0.71 $-0.60
Growth Rates 3
Annual Growth Rates data for CBIO
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 3-point trend, +2.2% · · -86.7% -93.5% -88.6% · · · · · · ·
Revenue CAGR 3Y 2-point trend, +571.8% 424.9% · -90.0% · · · · · · · · ·
Revenue CAGR 5Y 1.3% · · · · · · · · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for CBIO
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 8-point trend, -27.8% $11M · $10.0K $75.0K $1M $10M · · · $18.5K $20M $15M
Net Income TTM 12-point trend, -1284.2% $-154M $-38M $-37M $-47M $-63M $-51M $-58M $-48M $-33M $-32M $-13M $-11M
Market Cap 12-point trend, -97.6% $327M $1.61B $15.20B $16.48B $7.53B $18.43B $22.99B $40.87B $57.69B $14.18B $10.90B $13.64B
P/E 12-point trend, +98.0% -24.2 -42.4 -406.9 -340.4 -117.1 -335.7 -394.8 -1262.7 -2238.7 -813.3 -805.6 -1200.0
P/S 8-point trend, -96.7% 30.1 · 1519692.4 219686.3 6495.4 1813.5 · · · 766622.4 542.9 907.5
P/B 12-point trend, -99.4% 1.6 303.4 395.6 383.8 92.3 143.7 149.1 198.9 481.9 401.8 269.2 268.4
P / Tangible Book 5-point trend, -98.9% 1.6 · 395.6 383.8 92.3 143.7 · · · · · ·
P / Cash Flow 12-point trend, +99.9% -4.6 -51.8 -435.7 -354.7 -131.0 -469.7 -442.3 -943.3 -1938.0 -477.0 -1322.1 -3185.0
P / FCF 12-point trend, +99.9% -4.5 -51.8 -435.4 -354.0 -131.0 -468.8 -441.1 -940.5 -1919.0 -466.0 -1280.4 -3034.3
Earnings Yield 12-point trend, -5062.5% -4.1% -2.4% -0.25% -0.29% -0.85% -0.30% -0.25% -0.08% -0.04% -0.12% -0.12% -0.08%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $11M$10.0K$75.0K$1M
Operating Margin % -1407.5%-392752.9%-63204.4%-5470.7%
Net Income $-154M$-38M$-37M$-47M$-63M
Diluted EPS $-0.59$-0.58$-0.89$-1.23
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 6.61.96.45.77.7
Quick Ratio 6.41.96.15.47.6
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-72M$-31M$-35M$-47M$-58M

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