Performance vs S&P 500

03
Tracked Q1 2025–Q2 2026 +174.5%
S&P 500 total return (same window) +37.0%
Excess return +137.5%

Annualized: +124.4% · S&P 500: +28.7%

Approximates a buy-and-hold portfolio built from quarterly SEC 13F snapshots. Excludes cash, short positions, options/derivatives, and non-13(f) securities — reflects the disclosed long-equity book only, not total fund AUM. SEC filing lag is up to 45 days; this is not a real-time-copyable timing.

Priceable coverage: 98.5% · Options excluded: 0.0%

Sector breakdown

04
Healthcare 72.2%
Other/Unmapped 27.8%

Full portfolio 7 positions

05
Type Streak 8Q trend
PHVS Pharvaris N.V. - Ordinary Shares $160,569,809 30.92% 4,643,430 $29,509,471 Up ×1
Unknown issuer (CUSIP: 698955101) $144,149,497 27.75% 5,266,697 Up ×1
ALMS Alumis Inc. - Common Stock $127,429,401 24.53% 4,528,408 $27,668,573
ACHV Achieve Life Sciences, Inc. - Common Shares $38,623,122 7.44% 5,914,720 Up ×1
ALXO ALX Oncology Holdings Inc. - Common Stock $26,671,201 5.14% 12,884,638 $837,502
HRMY Harmony Biosciences Holdings, Inc. - Common Stock $17,192,584 3.31% 472,194 $3,490,260 Down ×1
LYEL Lyell Immunopharma, Inc. - Common Stock $4,744,643 0.91% 337,697 $-2,029,559

Biggest new bets

09

New positions opened this quarter, largest first.

SecurityValueShares% of portfolio
Unknown issuer (CUSIP: 698955101) $144,149,497 5,266,697 27.75%
ACHV $38,623,122 5,914,720 7.44%

Top movers (QoQ)

10
SecurityActionShares ΔValue Δ
PHVS Bought more +4K +$29.5M
ALMS Price move only +0 +$27.7M
HRMY Trimmed -17K +$3.5M
LYEL Price move only +0 -$2.0M
ALXO Price move only +0 +$838K

Exited positions

11

Includes corporate events (mergers, delistings) — not all exits are sells

Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.

SecurityQuarterShares beforeValue beforePrice since exit
SLRN June 30, 2025 3,806,410 $9,401,833 No longer tracked
LYEL (filed as LYELXXXX) June 30, 2025 7,102,190 $3,820,978 4.8%
ARTV June 30, 2026 531,337 $3,421,810 -29.6%