your badges 52W Range $4–$31 11% of range Analyst Rating STRONG BUY 16 analysts Price Target $32 +369% upside P/E -1.9 ROE -93.6% Net Profit Margin -5933.5%

ALMS Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $6.85
P/E (TTM) -1.9
EPS (TTM) $-3.66
Revenue (TTM) $7M
ROE (TTM) -93.6%
52W Range $4–$31

ALMS Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

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10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$24M
2025-12-31 → 2025-12-31
EPS$-2.86
2023-12-31 → 2025-12-31
Free Cash Flow$-370M
2025-12-31 → 2025-12-31
Net margin-5933.5%
2025-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend ALMS 5Y avg Peer Median Verdict
P/E (TTM) -1.9 · · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

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Avg Surprise 5.0%
Next Report Nov 11, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 13, 2026 $-0.79 $-0.74 -6.2%
March 31, 2026 May 14, 2026 $-0.74 $-0.78 4.7%
Dec. 31, 2025 $-0.94 $-1.00 5.8%
Sept. 30, 2025 $-1.06 $-0.93 -13.4%
June 30, 2025 $-1.68 $-1.41 -19.6%
March 31, 2025 $-1.82 $-1.52 -20.1%
Dec. 31, 2024 $-0.23 $-1.42 83.8%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 14
Metric Trend 2025
Revenue $24M
R&D Expense $386M
SG&A Expense $92M
Operating Expenses $478M
Operating Income $-454M
Other Non-op $-169.0K
Pretax Income $-252M
Income Tax $-9M
Net Income $-243M
EPS (Basic) $-2.86
EPS (Diluted) $-2.86
Shares (Basic) 85,029,624
Shares (Diluted) 85,029,624
EBITDA $-450M
Balance Sheet 20
Metric Trend 2025
Cash & Equivalents $90M
Short-term Investments $219M
Prepaid Expense $7M
Current Assets $318M
PP&E (Net) $18M
PP&E (Gross) $26M
Accum. Depreciation $8M
Other Non-current Assets $6M
Total Assets $412M
Accounts Payable $10M
Current Liabilities $73M
Capital Leases $32M
Deferred Tax $2M
Other Non-current Liabilities $207.0K
Total Liabilities $111M
Paid-in Capital $1.20B
Retained Earnings $-902M
AOCI $188.0K
Stockholders' Equity $301M
Liabilities + Equity $412M
Cash Flow 11
Metric Trend 2025
D&A $3M
Stock-based Comp $44M
Deferred Tax $-9M
Other Non-cash $-165M
Operating Cash Flow $-370M
CapEx $653.0K
Investing Cash Flow $288M
Stock Repurchased $17.0K
Net Stock Activity $-17.0K
Financing Cash Flow $2M
Free Cash Flow $-370M
Profitability 7
Metric Trend 2025
Operating Margin -1886.9%
Net Margin -1011.8%
Pretax Margin -1047.3%
EBITDA Margin -1872.4%
ROA -64.6%
ROE -61.9%
ROIC -145.5%
Liquidity & Solvency 2
Metric Trend 2025
Current Ratio 4.3
Quick Ratio 4.2
Efficiency 1
Metric Trend 2025
Asset Turnover 0.1
Per Share 3
Metric Trend 2025
Revenue / Share $0.28
Cash Flow / Share $-4.35
EPS (TTM) $-2.86
Valuation (TTM) 4
Metric Trend 2025
Revenue TTM $24M
Net Income TTM $-243M
P/E -3.4
Earnings Yield -29.3%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-31
Revenue $24M · ·
Operating Margin % -1886.9% · ·
Net Income $-243M $-294M $-155M
Diluted EPS $-2.86 $-10.38 $-72.08

Institutional owners (13F) 218 filers · $3.2B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 218
Value held $3.2B
New positions 27
Exited positions 21
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
27 (-71 vs prior Q) 21 (0 vs prior Q) 81 (+16 vs prior Q) 66 (+34 vs prior Q) +3.5M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
AyurMaya Capital Management Company, LP $426,031,355 15,139,707 13.18% Shares
BlackRock, Inc. $231,258,771 8,218,151 7.16% Shares
FMR LLC $190,484,444 6,769,170 5.89% Shares
Deep Track Capital, LP $178,648,422 6,348,558 5.53% Shares
SAMSARA BIOCAPITAL, LLC $178,554,463 6,345,219 5.53% Shares
Foresite Capital Management V, LLC $165,941,439 5,896,995 5.14% Shares
venBio Partners LLC $127,429,401 4,528,408 3.94% Shares
Foresite Capital Management VI LLC $119,529,434 4,247,670 3.70% Shares
VANGUARD CAPITAL MANAGEMENT LLC $118,629,882 4,215,703 3.67% Shares
Nextech Invest Ltd. $99,643,684 3,540,998 3.08% Shares
Cormorant Asset Management, LP $92,456,671 3,285,596 2.86% Shares
Saturn V Capital Management LP $82,040,566 2,915,443 2.54% Shares
Octagon Capital Advisors LP $79,655,898 2,830,700 2.47% Shares
STATE STREET CORP $61,549,665 2,187,266 1.90% Shares
GEODE CAPITAL MANAGEMENT, LLC $61,033,791 2,168,517 1.89% Shares
MPM BIOIMPACT LLC $56,815,223 2,019,020 1.76% Shares
BAKER BROS. ADVISORS LP $56,631,750 2,012,500 1.75% Shares
SR One Capital Management, LP $55,151,473 1,959,896 1.71% Shares
JANUS HENDERSON GROUP PLC $46,790,086 2,124,408 1.45% Shares
VANGUARD GROUP INC $40,048,110 4,103,290 1.24% Shares
Invesco Ltd. $33,022,796 1,173,518 1.02% Shares
NOVO HOLDINGS A/S $30,954,000 1,100,000 0.96% Shares
PRINCIPAL FINANCIAL GROUP INC $30,055,208 1,068,060 0.93% Shares
D. E. Shaw & Co., Inc. $27,246,105 968,234 0.84% Shares
UBS Group AG $26,783,540 951,796 0.83% Shares
JPMORGAN CHASE & CO $26,407,356 969,617 0.82% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $25,922,878 921,211 0.80% Shares
Ikarian Capital, LLC $24,497,220 870,548 0.76% Shares
GREAT POINT PARTNERS LLC $24,089,557 856,061 0.75% Shares
GOLDMAN SACHS GROUP INC $23,409,581 831,897 0.72% Shares
NORTHERN TRUST CORP $20,369,111 723,849 0.63% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $19,701,771 700,134 0.61% Shares
Integral Health Asset Management, LLC $19,698,000 700,000 0.61% Shares
MILLENNIUM MANAGEMENT LLC $18,576,396 660,142 0.57% Shares
VANGUARD FIDUCIARY TRUST CO $17,221,961 612,010 0.53% Shares
Opaleye Management Inc. $15,477,000 550,000 0.48% Shares
ORBIMED ADVISORS LLC $15,425,307 548,163 0.48% Shares
ROYCE & ASSOCIATES LP $14,782,026 525,303 0.46% Shares
Woodline Partners LP $13,677,503 486,052 0.42% Shares
Spruce Street Capital LP $11,047,032 392,574 0.34% Shares
Trium Capital LLP $10,982,142 390,268 0.34% Shares
CITIGROUP INC $10,845,156 385,400 0.34% Shares
TWO SIGMA INVESTMENTS, LP $10,583,989 376,119 0.33% Shares
MARSHALL WACE, LLP $10,355,915 368,014 0.32% Shares
Ikarian Capital, LLC $10,026,282 356,300 0.31% Call option
MORGAN STANLEY $9,037,528 321,163 0.28% Shares
VOLORIDGE INVESTMENT MANAGEMENT, LLC $9,029,029 320,861 0.28% Shares
Weiss Asset Management LP $8,761,980 311,371 0.27% Shares
Artia Global Partners LP $7,838,284 278,546 0.24% Shares
BARCLAYS PLC $7,702,368 273,716 0.24% Shares

Show all 218 institutional owners →

Activists & 5%+ owners 4 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Foresite Capital Fund VI LP, Foresite Capital Management VI, LLC, Foresite Capital Fund V, L.P., Foresite Capital Management V, LLC, Foresite Capital Opportunity Fund V, L.P., Foresite Capital Opportunity Management V, LLC, James B. Tananbaum ×5 filings Aug. 17, 2026 14.50% Initial filing Passive investment SEC
AyurMaya Capital Management Company, LP, David E. Goel ×4 filings July 2, 2026 12.30% Amendment · SEC
Samsara BioCapital, L.P., Samsara BioCapital GP, LLC, Samsara Opportunity Fund, L.P., Samsara Opportunity Fund GP, LLC, Srinivas Akkaraju ×5 filings Jan. 13, 2026 5.40% Amendment · SEC
Foresite Capital Fund VI, L.P. (“Fund VI”), Foresite Capital Management VI, LLC (“FCM VI”), Foresite Capital Fund V, L.P. (“Fund V”), Labs Co-Invest V, LLC (“Labs Co-Invest”), Foresite Capital Management V, LLC (“FCM V”), Foresite Capital Opportunity Fund V, L.P. (“Opportunity Fund V”), Foresite Capital Opportunity Management V, LLC (“FCOM V”), Foresite Labs Fund I, L.P. (“Labs Fund I”), Foresite Labs Management I, LLC (“FLM I”), Foresite Labs Affiliates 2021, LLC (“Labs Affiliates”), Foresite Labs, LLC (“Labs”), James B. Tananbaum (“Tananbaum”) July 5, 2024 · Initial filing Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 16 insiders · 9 officers · 8 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Martin Babler President, CEO and Chairman Jan. 26, 2026 A 106,454 0 0 $0
John R. Schroer Chief Financial Officer Aug. 3, 2026 S 24,718 0 1 $-86,546
Sanam Pangali Chief Legal Officer Aug. 3, 2026 S 9,747 0 2 $-175,969
Mark Christopher Bradley Chief Development Officer Aug. 3, 2026 S 48,533 0 1 $-67,824
Jorn Drappa Chief Medical Officer Aug. 3, 2026 S 56,892 0 1 $-64,527
David M Goldstein Chief Scientific Officer Aug. 3, 2026 S 30,970 0 1 $-68,457
Roy C. Hardiman Chief Business & Strategy Ofcr Aug. 3, 2026 S 207,746 0 1 $-70,988
Derrick Richardson SVP, People and Culture July 29, 2025 A 42,800 0 0 $0
Sara Klein Chief Legal Officer Feb. 18, 2025 A 33,796 0 0 $0
Srinivas Akkaraju Director Sept. 8, 2026 P 2,298,783 19 2 $28,781,826
Lynn A. Tetrault Director June 30, 2026 A 3,553 0 0 $0
Sapna Srivastava Director June 30, 2026 A 3,553 0 0 $0
Zhengbin Yao Director June 30, 2026 A 27,082 0 0 $0
Patrick Machado Director June 30, 2026 A 3,553 0 0 $0
James B. Tananbaum Director April 1, 2026 J 680,486 7 0 $10,627,638
Alan Colowick Director April 2, 2025 P 18,404 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 31 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PILL · Direxion Shares ETF Trust 1.60% 11,709 NS July 31, 2026 N-PORT
BBC · ETFis Series Trust I 0.78% 12,870 NS July 31, 2026 N-PORT
JDOC · J.P. Morgan Exchange-Traded Fund Tr… 0.57% 1,834 NS July 31, 2026 N-PORT
FYC · First Trust Exchange-Traded AlphaDE… 0.40% 183,577 NS July 31, 2026 N-PORT
IHE · iShares Trust 0.19% 315,239 SH Sept. 11, 2026 Daily
FYX · First Trust Exchange-Traded AlphaDE… 0.19% 93,000 NS July 31, 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0.18% 126,318 SH Aug. 19, 2026 Daily
NUSC · Nushares ETF Trust 0.14% 65,999 NS July 31, 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0.13% 84,673 SH Aug. 19, 2026 Daily
FFSM · FIDELITY COVINGTON TRUST 0.13% 68,851 NS July 31, 2026 N-PORT
BKSE · BNY Mellon ETF Trust 0.09% 2,847 NS July 31, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.08% 16,630 NS July 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.08% 19,808 NS July 31, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.07% 454,674 SH Aug. 19, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.06% 9,159 SH Oct. 1, 2026 Daily
IBB · iShares Trust 0.06% 642,829 SH Sept. 11, 2026 Daily
IWO · iShares Trust 0.05% 736,616 SH Sept. 11, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.03% 976,842 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.03% 203,834 SH Aug. 19, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.03% 32,186 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.03% 2,019,132 SH Sept. 11, 2026 Daily
ESML · iShares Trust 0.02% 61,022 SH Sept. 11, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 76,856 SH Oct. 1, 2026 Daily
WSML · iShares Trust 0.01% 3,980 SH Sept. 11, 2026 Daily
ITOT · iShares Trust 0.00% 113,341 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.00% 23,246 SH Sept. 10, 2026 Daily
DFAU · Dimensional ETF Trust 0.00% 612 NS July 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 3,140,764 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 6,510 SH Aug. 19, 2026 Daily
DFAT · Dimensional ETF Trust 0.00% 1 NS July 31, 2026 N-PORT
ISCB · iShares Trust · 3,324 SH Sept. 11, 2026 Daily

ALMS Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 16 analysts BUY
Median target $32.00 +367.2%
8 50.0% Strong Buy
6 37.5% Buy
2 12.5% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

8 analysts · 2026-09-30

Mean target $32.12 +369.0%

← Below all targets Current price $6.85
Low$15.00 Mean$32.12 High$46.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ALMS · -3.4 · -1011.8% -61.9% ·
AMPH $1.22B 13.2 -1.7% 13.6% 12.7% 49.5%
PCRX $1.06B 161.8 3.6% 0.97% 0.97% ·
ANRO $568M -8.1 · · -46.1% ·
SPTX · · · · · ·
APMD · · · · · ·
SGP · · · · 50.0% ·
LXRX $421M -8.2 60.2% -101.1% -39.7% ·
COLL $1.47B 26.8 23.6% 8.1% 23.5% 59.4%
LLY · 46.8 44.7% 31.7% 101.2% ·

Latest News Recent headlines mentioning this company

23
This Biotech Stock Is Up 355%. One Fund Added a $169 Million Position Last Quarter Nasdaq · 4 months, 1 week ago Alumis Stock Is Up Over 300%. One Major Healthcare Investor Is Cutting Back Nasdaq · 4 months, 2 weeks ago Why One Fund’s $4 Million Alumis Buy Looks Like a Bet on a Breakthrough Autoimmune Drug Nasdaq · 4 months, 3 weeks ago

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Source: SEC 10-Q filed Aug 13, 2026