ALMS Alumis Inc. - Common Stock

NASDAQ · Pharmaceuticals · View on SEC EDGAR ↗
$25.56
Price · Aug 19, 2026
Fundamentals as of Aug 13, 2026
52W Range
$4–$31
79% of range
Analyst Rating
STRONG BUY
16 analysts
Price Target
$40
+58% upside
P/E (TTM)
-3.4
ROE
-61.9%
Net Profit Margin
-1011.8%

ALMS Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$25.55
Market Cap
—
P/E (TTM)
-3.4
EPS (TTM)
$-2.86
Revenue (TTM)
$24M
Div Yield
—
ROE
-61.9%
Debt/Equity
—
52W Range
$4 – $31

ALMS Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $24M
2025-12-31 → 2025-12-31
EPS $-2.86
3-point trend, +96.0%
2023-12-31 → 2025-12-31
Free Cash Flow $-370M
2025-12-31 → 2025-12-31
Margins -1011.8%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
ALMS
Peer Median
P/E (TTM)
2-point trend, -350.7%
-3.4
38.7

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
ALMS
Peer Median
Operating Margin
-1886.9%
—
Net Profit Margin
-1011.8%
15.3%
ROA
-64.6%
-6.4%
ROE
-61.9%
-16.8%
ROIC
-145.5%
—

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
ALMS
Peer Median
Current Ratio
4.3
12.8
Quick Ratio
4.2
—

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
ALMS
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
ALMS
Peer Median
EPS (Diluted)
3-point trend, +96.0%
$-2.86
—

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
ALMS
Peer Median

ALMS Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 16 analysts
  • Strong Buy 8 50.0%
  • Buy 6 37.5%
  • Hold 2 12.5%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

9 analysts · 2026-08-19
Median target $39.00 +52.6%
Mean target $40.33 +57.8%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.10%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.74 $-0.78 0.04%
Dec. 31, 2025 $-0.94 $-1.00 0.06%
Sept. 30, 2025 $-1.06 $-0.93 -0.13%
June 30, 2025 $-1.68 $-1.41 -0.27%
March 31, 2025 $-1.82 $-1.52 -0.30%
Dec. 31, 2024 $-0.23 $-1.42 1.2%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ALMS — -3.4 — -1011.8% -61.9% —
ELVN $915M -8.4 — — -21.9% —
GPCR $14.78B -86.9 — — -12.3% —
OGN $1.87B 10.0 -2.9% 3.0% 25.2% 53.3%
MBX $1.42B -13.3 — — -29.6% —
AMLX $1.33B -7.9 -77.1% — -61.2% —
TARS $3.48B -51.5 146.7% -14.7% -19.7% —
SUPN $2.86B -73.1 8.6% -5.4% -3.6% —
ATAI $223M -1.4 -1.9% -48464.0% -83.1% —
TRVI $1.61B -39.1 — — -22.4% —

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for ALMS
Metric Trend 2025
Revenue $24M
R&D Expense $386M
SG&A Expense $92M
Operating Expenses $478M
Operating Income $-454M
Other Non-op $-169.0K
Pretax Income $-252M
Income Tax $-9M
Net Income $-243M
EPS (Basic) $-2.86
EPS (Diluted) $-2.86
Shares (Basic) 85,029,624
Shares (Diluted) 85,029,624
EBITDA $-450M
Balance Sheet 20
Annual Balance Sheet data for ALMS
Metric Trend 2025
Cash & Equivalents $90M
Short-term Investments $219M
Prepaid Expense $7M
Current Assets $318M
PP&E (Net) $18M
PP&E (Gross) $26M
Accum. Depreciation $8M
Other Non-current Assets $6M
Total Assets $412M
Accounts Payable $10M
Current Liabilities $73M
Capital Leases $32M
Deferred Tax $2M
Other Non-current Liabilities $207.0K
Total Liabilities $111M
Paid-in Capital $1.20B
Retained Earnings $-902M
AOCI $188.0K
Stockholders' Equity $301M
Liabilities + Equity $412M
Cash Flow 11
Annual Cash Flow data for ALMS
Metric Trend 2025
D&A $3M
Stock-based Comp $44M
Deferred Tax $-9M
Other Non-cash $-165M
Operating Cash Flow $-370M
CapEx $653.0K
Investing Cash Flow $288M
Stock Repurchased $17.0K
Net Stock Activity $-17.0K
Financing Cash Flow $2M
Free Cash Flow $-370M
Profitability 7
Annual Profitability data for ALMS
Metric Trend 2025
Operating Margin -1886.9%
Net Margin -1011.8%
Pretax Margin -1047.3%
EBITDA Margin -1872.4%
ROA -64.6%
ROE -61.9%
ROIC -145.5%
Liquidity & Solvency 2
Annual Liquidity & Solvency data for ALMS
Metric Trend 2025
Current Ratio 4.3
Quick Ratio 4.2
Efficiency 1
Annual Efficiency data for ALMS
Metric Trend 2025
Asset Turnover 0.1
Per Share 3
Annual Per Share data for ALMS
Metric Trend 2025
Revenue / Share $0.28
Cash Flow / Share $-4.35
EPS (TTM) $-2.86
Valuation (TTM) 4
Annual Valuation (TTM) data for ALMS
Metric Trend 2025
Revenue TTM $24M
Net Income TTM $-243M
P/E -3.4
Earnings Yield -29.3%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-31
Revenue $24M——
Operating Margin % -1886.9%——
Net Income $-243M$-294M$-155M
Diluted EPS $-2.86$-10.38$-72.08
Balance Sheet
2025-12-312024-12-312023-12-31
Current Ratio 4.3——
Quick Ratio 4.2——
Cash Flow
2025-12-312024-12-312023-12-31
Free Cash Flow $-370M——

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 219 filers · $2.8B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
32 (-60 vs prior Q) 20 (-1 vs prior Q) 75 (+13 vs prior Q) 64 (+30 vs prior Q) +12.9M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
AyurMaya Capital Management Company, LP $426,031,355 15,139,707 15.31% Shares
Deep Track Capital, LP $178,648,422 6,348,558 6.42% Shares
SAMSARA BIOCAPITAL, LLC $178,554,463 6,345,219 6.42% Shares
FMR LLC $167,396,981 5,948,720 6.02% Shares
Foresite Capital Management V, LLC $165,941,439 5,896,995 5.96% Shares
venBio Partners LLC $127,429,401 4,528,408 4.58% Shares
Foresite Capital Management VI LLC $119,529,434 4,247,670 4.30% Shares
VANGUARD CAPITAL MANAGEMENT LLC $118,629,882 4,215,703 4.26% Shares
Nextech Invest Ltd. $99,643,684 3,540,998 3.58% Shares
Cormorant Asset Management, LP $92,456,671 3,285,596 3.32% Shares
Saturn V Capital Management LP $82,040,566 2,915,443 2.95% Shares
Octagon Capital Advisors LP $79,655,898 2,830,700 2.86% Shares
STATE STREET CORP $61,549,665 2,187,266 2.21% Shares
MPM BIOIMPACT LLC $56,815,223 2,019,020 2.04% Shares
BAKER BROS. ADVISORS LP $56,631,750 2,012,500 2.04% Shares
SR One Capital Management, LP $55,151,473 1,959,896 1.98% Shares
GEODE CAPITAL MANAGEMENT, LLC $52,423,177 1,862,525 1.88% Shares
JANUS HENDERSON GROUP PLC $46,151,361 2,095,408 1.66% Shares
NOVO HOLDINGS A/S $30,954,000 1,100,000 1.11% Shares
PRINCIPAL FINANCIAL GROUP INC $29,885,271 1,062,021 1.07% Shares
D. E. Shaw & Co., Inc. $27,246,105 968,234 0.98% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $25,922,878 921,211 0.93% Shares
Ikarian Capital, LLC $24,497,220 870,548 0.88% Shares
GREAT POINT PARTNERS LLC $24,089,557 856,061 0.87% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $19,701,771 700,134 0.71% Shares
Integral Health Asset Management, LLC $19,698,000 700,000 0.71% Shares
MILLENNIUM MANAGEMENT LLC $18,576,396 660,142 0.67% Shares
VANGUARD FIDUCIARY TRUST CO $17,221,961 612,010 0.62% Shares
Opaleye Management Inc. $15,477,000 550,000 0.56% Shares
ORBIMED ADVISORS LLC $15,425,307 548,163 0.55% Shares
GOLDMAN SACHS GROUP INC $15,172,778 539,189 0.55% Shares
ROYCE & ASSOCIATES LP $14,782,026 525,303 0.53% Shares
Woodline Partners LP $13,677,503 486,052 0.49% Shares
Nextech Invest Ltd. $11,609,204 1,476,998 0.42% Shares
Spruce Street Capital LP $11,047,032 392,574 0.40% Shares
Trium Capital LLP $10,982,142 390,268 0.39% Shares
CITIGROUP INC $10,697,196 380,142 0.38% Shares
TWO SIGMA INVESTMENTS, LP $10,583,989 376,119 0.38% Shares
Ikarian Capital, LLC $10,026,282 356,300 0.36% Call option
VOLORIDGE INVESTMENT MANAGEMENT, LLC $9,029,029 320,861 0.32% Shares
Weiss Asset Management LP $8,761,980 311,371 0.31% Shares
Artia Global Partners LP $7,838,284 278,546 0.28% Shares
Yu Fan $7,110,190 252,672 0.26% Shares
BOOTHBAY FUND MANAGEMENT, LLC $6,825,019 242,538 0.25% Shares
Omega Fund Management, LLC $6,788,916 241,255 0.24% Shares
SCHRODER INVESTMENT MANAGEMENT GROUP $6,413,806 236,323 0.23% Shares
TOWERVIEW LLC $6,255,353 222,294 0.22% Shares
JPMORGAN CHASE & CO $5,970,230 216,591 0.21% Shares
Exome Asset Management LLC $5,752,323 204,418 0.21% Shares
DIADEMA PARTNERS LP $5,628,000 200,000 0.20% Call option
HighVista Strategies LLC $5,627,100 199,968 0.20% Shares
TYBOURNE CAPITAL MANAGEMENT (HK) LTD $5,583,008 1,399,250 0.20% Shares
MARSHALL WACE, LLP $5,458,767 193,986 0.20% Shares
BANK OF AMERICA CORP /DE/ $5,409,184 192,224 0.19% Shares
Susquehanna Portfolio Strategies, LLC $4,862,001 172,779 0.17% Shares
BlackRock, Inc. $4,784,841 170,037 0.17% Shares
Ensign Peak Advisors, Inc $4,135,736 146,970 0.15% Shares
VANGUARD GROUP INC $3,906,303 400,236 0.14% Shares
MOORE CAPITAL MANAGEMENT, LP $3,849,636 136,803 0.14% Shares
Swiss National Bank $3,824,226 135,900 0.14% Shares
STEMPOINT CAPITAL LP $3,819,611 135,736 0.14% Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $3,795,000 134,850 0.14% Shares
VICTORY CAPITAL MANAGEMENT INC $3,723,794 132,331 0.13% Shares
Quantinno Capital Management LP $3,688,929 131,092 0.13% Shares
Elmind Capital, LP $3,658,200 130,000 0.13% Shares
PRUDENTIAL FINANCIAL INC $3,474,812 123,483 0.12% Shares
WELLS FARGO & COMPANY/MN $3,145,377 111,776 0.11% Shares
STIFEL FINANCIAL CORP $3,097,510 110,075 0.11% Shares
BOOTHBAY FUND MANAGEMENT, LLC $2,943,444 104,600 0.11% Call option
MANUFACTURERS LIFE INSURANCE COMPANY, THE $2,820,050 100,215 0.10% Shares
Caption Management, LLC $2,814,000 100,000 0.10% Call option
Ghisallo Capital Management LLC $2,814,000 100,000 0.10% Shares
TD Asset Management Inc $2,729,636 97,002 0.10% Shares
RHUMBLINE ADVISERS $2,723,010 96,767 0.10% Shares
FIRST TRUST ADVISORS LP $2,646,454 94,046 0.10% Shares
Harvest Investment Services, LLC $2,610,407 92,765 0.09% Shares
BARCLAYS PLC $2,596,309 92,264 0.09% Shares
Caption Management, LLC $2,532,600 90,000 0.09% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $2,490,390 88,500 0.09% Call option
ALLIANCEBERNSTEIN L.P. $2,299,800 104,394 0.08% Shares
Ally Bridge Group (NY) LLC $2,151,556 76,459 0.08% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $2,040,150 72,500 0.07% Put option
Mariner, LLC $2,018,263 71,726 0.07% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $1,781,015 80,845 0.06% Shares
WELLINGTON MANAGEMENT GROUP LLP $1,725,657 61,324 0.06% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,652,296 58,717 0.06% Shares
ALGERT GLOBAL LLC $1,625,648 57,770 0.06% Shares
CITADEL ADVISORS LLC $1,581,468 56,200 0.06% Call option
ACT CAPITAL MANAGEMENT, LLC $1,452,024 51,600 0.05% Shares
VANGUARD ASSET MANAGEMENT, Ltd $1,424,306 50,615 0.05% Shares
STATE OF WISCONSIN INVESTMENT BOARD $1,418,622 50,413 0.05% Shares
Vanguard Global Advisers, LLC $1,400,134 49,756 0.05% Shares
Squarepoint Ops LLC $1,339,183 47,590 0.05% Shares
MetLife Investment Management, LLC $1,303,220 46,312 0.05% Shares
CITADEL ADVISORS LLC $1,224,090 43,500 0.04% Put option
FRED ALGER MANAGEMENT, LLC $1,211,624 43,057 0.04% Shares
JANE STREET GROUP, LLC $1,136,856 40,400 0.04% Put option
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1,023,536 36,373 0.04% Shares
Corient Private Wealth LP $997,142 35,435 0.04% Shares
Trexquant Investment LP $960,615 34,137 0.03% Shares

Company insiders 12 insiders · 0 officers · 6 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Lynn A. Tetrault Director June 30, 2026 A 3,553 0 0 $0
Sapna Srivastava Director June 30, 2026 A 3,553 0 0 $0
Zhengbin Yao Director June 30, 2026 A 27,082 0 0 $0
Patrick Machado Director June 30, 2026 A 3,553 0 0 $0
Srinivas Akkaraju Director June 30, 2026 A 3,553 15 0 $19,069,488
James B. Tananbaum Director April 1, 2026 J 680,486 7 0 $10,627,638
Sanam Pangali — Aug. 3, 2026 S 9,747 0 2 $-175,969
Mark Christopher Bradley — Aug. 3, 2026 S 48,533 0 1 $-67,824
Jorn Drappa — Aug. 3, 2026 S 56,892 0 1 $-64,527
David M Goldstein — Aug. 3, 2026 S 30,970 0 1 $-68,457
John R. Schroer — Aug. 3, 2026 S 24,718 0 1 $-86,546
Roy C. Hardiman — Aug. 3, 2026 S 207,746 0 1 $-70,988

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 4 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Foresite Capital Fund VI LP, Foresite Capital Management VI, LLC, Foresite Capital Fund V, L.P., Foresite Capital Management V, LLC, Foresite Capital Opportunity Fund V, L.P., Foresite Capital Opportunity Management V, LLC, James B. Tananbaum ×5 filings Aug. 17, 2026 14.50% Initial filing Passive investment SEC
AyurMaya Capital Management Company, LP, David E. Goel ×4 filings July 2, 2026 12.30% Amendment — SEC
Samsara BioCapital, L.P., Samsara BioCapital GP, LLC, Samsara Opportunity Fund, L.P., Samsara Opportunity Fund GP, LLC, Srinivas Akkaraju ×5 filings Jan. 13, 2026 5.40% Amendment — SEC
Foresite Capital Fund VI, L.P. (“Fund VI”), Foresite Capital Management VI, LLC (“FCM VI”), Foresite Capital Fund V, L.P. (“Fund V”), Labs Co-Invest V, LLC (“Labs Co-Invest”), Foresite Capital Management V, LLC (“FCM V”), Foresite Capital Opportunity Fund V, L.P. (“Opportunity Fund V”), Foresite Capital Opportunity Management V, LLC (“FCOM V”), Foresite Labs Fund I, L.P. (“Labs Fund I”), Foresite Labs Management I, LLC (“FLM I”), Foresite Labs Affiliates 2021, LLC (“Labs Affiliates”), Foresite Labs, LLC (“Labs”), James B. Tananbaum (“Tananbaum”) July 5, 2024 — Initial filing Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 38 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
BBC · ETFis Series Trust I 1.59% 24,020 NS April 30, 2026 N-PORT
PILL · Direxion Shares ETF Trust 1.25% 6,551 NS April 30, 2026 N-PORT
JDOC · J.P. Morgan Exchange-Traded Fund Tr… 0.54% 2,446 NS April 30, 2026 N-PORT
IHE · iShares Trust 0.52% 304,339 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.23% 6,715 SH Aug. 8, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.18% 126,318 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.18% 613,997 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.14% 4,674 NS May 31, 2026 N-PORT
IWO · iShares Trust 0.14% 718,737 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.13% 84,673 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.10% 99,832 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.07% 454,674 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.07% 2,015,040 SH Aug. 8, 2026 Daily
SMMV · iShares Trust 0.06% 6,398 SH Aug. 8, 2026 Daily
ESML · iShares Trust 0.06% 61,746 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.04% 3,225 NS May 31, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.04% 389,927 NS May 31, 2026 N-PORT
ISCB · iShares Trust 0.03% 3,324 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.03% 976,842 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.03% 203,834 SH Aug. 8, 2026 Daily
GSSC · Goldman Sachs ETF Trust 0.03% 11,873 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.03% 29,655 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.02% 2,523 NS May 31, 2026 N-PORT
WSML · iShares Trust 0.02% 3,939 SH Aug. 8, 2026 Daily
URTY · ProShares Trust 0.02% 2,551 NS May 31, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.01% 9,842 NS May 31, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.01% 33,350 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.01% 64 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.01% 1,965 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 113,351 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 22,996 SH Aug. 8, 2026 Daily
SCHB · SCHWAB STRATEGIC TRUST 0.00% 46,445 NS May 31, 2026 N-PORT
AVSU · AMERICAN CENTURY ETF TRUST 0.00% 60 NS May 31, 2026 N-PORT
AVUS · AMERICAN CENTURY ETF TRUST 0.00% 1,484 NS May 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 612 NS April 30, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 3,140,764 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 6,510 SH Aug. 8, 2026 Daily
DFAT · Dimensional ETF Trust 0.00% 1 NS April 30, 2026 N-PORT