Insider at

04

Insider transactions

05
4 buys (P) 0 sells (S) Net: $1,484,780 + 63 non-open-market transactions below 12 months to the week close of 2026-10-23

Price change vs the latest weekly close (updated to the current quote in your browser when available), split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

63 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
Dec. 16, 2025 AKTX P 618,658 · · 618,658 Direct · Acquired
Dec. 16, 2025 AKTX P 618,658 $0.40 $247,463 618,658 Direct · Acquired
Dec. 16, 2025 AKTX P 3,093,293 · · 3,093,293 Direct · Acquired
Dec. 16, 2025 AKTX P 3,093,293 $0.40 $1,237,317 3,093,293 Direct · Acquired

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
Aug. 18, 2026 AKTX Stock Option (Right to Buy) American Depositary Shares representing Ordinary Shares (30,000) $7.90 Aug. 18, 2036 30,000 Acquired
Aug. 18, 2026 AKTX Stock Option (Right to Buy) American Depositary Shares representing Ordinary Shares (15,000) $7.90 Aug. 18, 2036 15,000 Acquired
June 11, 2026 PLRX Stock Option (Right to Buy) Common Stock (70,000) $1.14 June 11, 2036 70,000 Acquired
Dec. 16, 2025 AKTX Warrants to purchase American Depositary Shares ("ADRs") [F1,F2] American Depositary Shares representing Ordinary Shares (618,658) $0.39 · 618,658 Acquired
Dec. 16, 2025 AKTX Pre-Funded Warrants to purchase ADRs [F1,F2] American Depositary Shares representing Ordinary Shares (618,658) · · 618,658 Acquired
Dec. 16, 2025 AKTX Warrants to purchase ADRs [F1,F5] American Depositary Shares representing Ordinary Shares (3,093,293) $0.39 · 3,093,293 Acquired
Dec. 16, 2025 AKTX Pre-Funded Warrants to purchase ADRs [F1,F5] American Depositary Shares representing Ordinary Shares (3,093,293) · · 3,093,293 Acquired
June 5, 2025 PLRX Common Stock (Right to Buy) Common Stock (30,000) $1.61 June 5, 2035 30,000 Acquired
March 20, 2025 AKTX Stock Option (Right to Buy) American Depositary Shares representing Ordinary Shares [F1] (175,000) $1.50 March 20, 2035 175,000 Acquired
March 20, 2025 AKTX Stock Option (Right to Buy) American Depositary Shares representing Ordinary Shares [F1] (225,000) $1.50 March 20, 2035 225,000 Acquired
March 6, 2025 AKTX Series A Warrants (Right to Buy) American Depositary Shares representing Ordinary Shares [F1] (892,857) $0.87 March 6, 2026 892,857 Acquired
March 6, 2025 AKTX Series B Warrants (Right to Buy) American Depositary Shares representing Ordinary Shares [F1] (892,857) $0.87 March 6, 2030 892,857 Acquired
June 13, 2024 PLRX Common Stock (Right to Buy) Common Stock (26,764) $13.06 June 13, 2034 26,764 Acquired
June 7, 2023 PLRX Stock Option (Right to Buy) Common Stock (14,000) $23.09 June 7, 2033 14,000 Acquired
June 16, 2022 PLRX Stock Option (right to buy) Common Stock (15,000) $6.80 June 15, 2032 15,000 Acquired
June 29, 2021 PLRX Stock Option (right to buy) Common Stock (13,286) $28.20 June 28, 2031 13,286 Acquired
June 5, 2020 PLRX Series A Preferred Stock Common Stock (139,860) · · 1,000,000 Acquired
June 13, 2018 CTMX Stock Option (Right to Buy) Common Stock (14,000) $25.25 June 12, 2028 14,000 Acquired
May 15, 2018 GERN Stock Option (right to buy) Common Stock (70,000) $3.43 May 14, 2028 70,000 Acquired
June 20, 2017 CTMX Stock Option (right to buy) Common Stock (14,000) $13.78 June 19, 2027 14,000 Acquired
May 9, 2017 GERN Stock Option (right to buy) Common Stock (50,000) $2.63 May 9, 2027 50,000 Acquired
Oct. 31, 2016 RZLT Stock Option (right to buy) Common Stock $1.20 Oct. 31, 2026 4,000,000 Acquired
June 10, 2016 CTMX Stock Option (right to buy) Common Stock (28,000) $10.17 June 9, 2026 28,000 Acquired
May 17, 2016 GERN Stock Option (right to buy) Common Stock (50,000) $2.74 May 17, 2026 50,000 Acquired
March 31, 2016 RZLT Warrant to purchase common stock Common Stock (234,700) $1.25 March 31, 2019 234,700 Acquired
May 18, 2015 GERN Stock Option (right to buy) Common Stock (35,000) $3.88 May 18, 2025 35,000 Acquired
May 20, 2014 GERN Stock Option (right to buy) Common Stock (35,000) $1.94 May 20, 2024 35,000 Acquired
May 22, 2013 GERN Stock Option (right to buy) Common Stock (35,000) $1.10 May 22, 2023 35,000 Acquired
May 17, 2012 GERN Stock Option (right to buy) Common Stock (35,000) $1.41 May 17, 2022 35,000 Acquired
April 30, 2012 RZLT Stock Option (right to buy) Common Stock (350,000) $3.12 April 30, 2019 350,000 Acquired
May 20, 2011 GERN Employee Stock Option (right to buy) Common Stock (15,000) $4.65 May 20, 2021 15,000 Acquired
May 20, 2011 GERN Employee Stock Option (right to buy) Common Stock (57,500) $4.65 May 20, 2021 57,500 Acquired
March 9, 2011 GERN Stock Option (right to buy) Common Stock (75,000) $5.00 March 9, 2021 75,000 Acquired
Dec. 2, 2008 NKTR Stock Option [F1] Common Stock (15,000) $5.15 Dec. 2, 2016 15,000 Acquired
Dec. 2, 2008 NKTR Restricted Stock Unit [F1] Common Stock (5,000) $0.01 · 5,000 Acquired
March 20, 2008 NKTR Stock Option [F1] Common Stock (37,500) $6.65 March 20, 2016 37,500 Acquired
March 3, 2008 NKTR Stock Option [F1] Common Stock (8,750) $6.95 March 3, 2016 8,750 Acquired
March 3, 2008 NKTR Restricted Stock Units Common Stock (2,900) $0.01 · 2,900 Acquired
March 3, 2008 NKTR Stock Option Common Stock (8,700) $6.95 March 3, 2016 8,700 Acquired
March 3, 2008 NKTR Restricted Stock Units Common Stock (2,900) $0.01 · 2,900 Acquired
Dec. 21, 2007 NKTR Employee Stock Option Common Stock (250,000) $6.98 Dec. 21, 2015 250,000 Acquired
June 6, 2007 NKTR Stock Option (Right to Buy) Common Stock (100,000) $10.84 June 6, 2015 100,000 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 18 holdings

07

Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Nov. 22, 2024 AKTX Ordinary Shares, par value $0.0001 per share [F1] 7,605,994,000 Direct
Nov. 22, 2024 AKTX Ordinary Shares, par value $0.0001 per share [F1] 218,914,000 Indirect
Nov. 22, 2024 AKTX Warrants (Right to Buy)→ Ordinary Shares, par value $0.0001 per share [F1] (103,482,000) 103,482,000 Direct
Nov. 22, 2024 AKTX Stock Option (Right to Buy)→ Ordinary Shares, par value $0.0001 per share [F1] (704,400,000) 704,400,000 Direct
June 2, 2020 PLRX Common Stock 99,759 Indirect
June 2, 2020 PLRX Series A Preferred Stock→ Common Stock (139,860) 139,860 Indirect
Oct. 7, 2015 CTMX Stock Option (right to buy)→ Common Stock (7,941) 7,941 Direct
Oct. 7, 2015 CTMX Stock Option (right to buy)→ Common Stock (95,301) 95,301 Direct
Oct. 7, 2015 CTMX Stock Option (right to buy)→ Common Stock (146,325) 146,325 Direct
Oct. 7, 2015 CTMX Stock Option (right to buy)→ Common Stock (110,426) 110,426 Direct
Feb. 8, 2013 RZLT Common Stock 4,000,000 Indirect
Feb. 8, 2013 RZLT Option to Purchase Common Stock→ Common Stock (2,500,000) 2,500,000 Direct
May 21, 2010 GERN Stock Option (right to buy)→ Common Stock (45,000) 45,000 Direct
May 29, 2007 NKTR Common Stock 8,000 Direct
May 29, 2007 NKTR Stock Option (Right to Buy)→ Common Stock (90,000) 90,000 Direct
May 29, 2007 NKTR Restricted Stock Unit→ Common Stock (12,000) 12,000 Direct
May 29, 2007 NKTR Stock Option (Right to Buy)→ Common Stock (10,000) 10,000 Direct
May 29, 2007 NKTR Stock Option (Right to Buy)→ Common Stock (40,000) 40,000 Direct

Holdings reported on Form 4 3 reported holdings

08

Positions listed on each Form 4 without a transaction in that filing (Table I and II holdings), newest filing first.

DateTickerSecuritySharesExercise priceExpirationOwnership
March 24, 2025 AKTX American Depositary Shares representing Ordinary Shares [F1] 4,695,854 · · Direct
March 24, 2025 AKTX American Depositary Shares representing Ordinary Shares [F1] 109,457 · · Indirect
March 10, 2025 AKTX American Depositary Shares representing Ordinary Shares [F1] 109,457 · · Indirect