PLRX Pliant Therapeutics, Inc. - Common Stock
$1.14
Price · Aug 18, 2026
Fundamentals as of Aug 11, 2026
52W Range
$1–$2
13% of range
Analyst Rating
HOLD
10 analysts
Price Target
$2
+119% upside
P/E (TTM)
-0.5
ROE
-74.4%
Net Profit Margin
—
About Pliant Therapeutics, Inc. - Common Stock Company overview from Wikipedia
PLRX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$1.14
Market Cap
$71M
P/E (TTM)
-0.5
EPS (TTM)
$-2.43
Revenue (TTM)
$0
Div Yield
—
ROE
-74.4%
Debt/Equity
—
52W Range
$1 – $2
PLRX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$0
2019-12-31
→
2025-12-31
EPS
$-2.43
2019-12-31
→
2025-12-31
Free Cash Flow
$-129M
2020-12-31
→
2025-12-31
Margins
—
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
PLRX
Peer Median
P/E (TTM)
-0.5
44.2
P/B
0.4
3.1
Price / FCF
-0.5
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
PLRX
Peer Median
ROA
-48.0%
-54.4%
ROE
-74.4%
-87.0%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
PLRX
Peer Median
Current Ratio
12.0
2.0
Quick Ratio
11.7
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
PLRX
Peer Median
Revenue YoY
-83.7%
—
Revenue CAGR 3Y
-66.4%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
PLRX
Peer Median
PLRX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
SELL
10 analysts
- Strong Buy 0 0.0%
- Buy 0 0.0%
- Hold 6 60.0%
- Sell 2 20.0%
- Strong Sell 2 20.0%
12-Month Price Target
2 analysts · 2026-08-16
Median
$2.50
← Below all targets
$1.14
Low
$2.00
High
$3.00
Median target
$2.50
+119.3%
Mean target
$2.50
+119.3%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-0.01%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $-0.32 | $-0.36 | 0.04% |
| Dec. 31, 2025 | $-0.38 | $-0.39 | 0.01% |
| Sept. 30, 2025 | $-0.43 | $-0.53 | 0.10% |
| June 30, 2025 | $-0.71 | $-0.71 | -0.00% |
| March 31, 2025 | $-0.92 | $-0.74 | -0.18% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| PLRX | $75M | -0.5 | -83.7% | — | -74.4% | — |
| LONA | $71M | -0.3 | — | — | -353.4% | — |
| CING | — | — | — | — | — | — |
| ELOX | — | — | — | — | 30.1% | — |
| TELO | $46M | -4.0 | — | — | -325.7% | — |
| IMA | — | -0.7 | -77.1% | -5668.6% | 192.1% | — |
| TLPH | $56M | — | — | -51035.7% | -120.8% | — |
| BSEM | — | — | — | — | — | — |
| SCLX | — | — | — | — | — | — |
| SCYX | $28M | -3.7 | 450.0% | -41.8% | -18.4% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 15
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $2M | $10M | $8M | $42M | $57M | |
| R&D Expense | $109M | $169M | $128M | $97M | $78M | $66M | $47M | |
| SG&A Expense | $47M | $59M | $58M | $40M | $28M | $17M | $11M | |
| Operating Expenses | $156M | $228M | $186M | $137M | $105M | $83M | $58M | |
| Operating Income | $-156M | $-228M | $-184M | $-127M | $-98M | $-42M | $-1M | |
| Interest Expense | · | · | $1M | $791.0K | $0 | · | · | |
| Interest Income | · | · | · | · | · | $478.0K | $816.0K | |
| Other Non-op | · | · | · | · | · | $-366.0K | $-216.0K | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-149M | $-210M | $-161M | $-123M | $-97M | $-42M | $-631.0K | |
| EPS (Basic) | $-2.43 | $-3.47 | $-2.75 | $-2.94 | $-2.71 | $-1.95 | $-4.22 | |
| EPS (Diluted) | $-2.43 | $-3.47 | $-2.75 | $-2.94 | $-2.71 | $-1.95 | $-4.22 | |
| Shares (Basic) | 61,366,887 | 60,538,639 | 58,719,083 | 42,015,908 | 35,846,421 | 21,344,236 | 1,623,358 | |
| Shares (Diluted) | 61,366,887 | 60,538,639 | 58,719,083 | 42,015,908 | 35,846,421 | 21,344,236 | 1,623,358 | |
| EBITDA | $-156M | $-228M | $-184M | $-127M | · | $-42M | · |
Balance Sheet 23
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $45M | $71M | $63M | $34M | $52M | $51M | $86M | |
| Short-term Investments | $145M | $285M | $431M | $298M | $149M | $226M | $17M | |
| Receivables | · | · | $0 | $2M | $2M | $9M | $7M | |
| Prepaid Expense | $4M | $7M | $11M | $7M | $7M | $4M | $2M | |
| Current Assets | $196M | $362M | $506M | $340M | $209M | $291M | $112M | |
| PP&E (Net) | $3M | $6M | $4M | $4M | $5M | $4M | $4M | |
| PP&E (Gross) | $14M | $16M | $12M | $11M | $10M | $8M | $6M | |
| Accum. Depreciation | $11M | $11M | $9M | $7M | $5M | $3M | $2M | |
| Other Non-current Assets | $392.0K | $435.0K | $392.0K | $394.0K | $838.0K | $451.0K | $3M | |
| Total Assets | $225M | $397M | $512M | $351M | $221M | $296M | $119M | |
| Accounts Payable | $480.0K | $6M | $5M | $2M | $3M | $2M | $1M | |
| Accrued Liabilities | $10M | $12M | $10M | $9M | $12M | $10M | $7M | |
| Current Liabilities | $16M | $33M | $29M | $24M | $17M | $12M | $8M | |
| Capital Leases | $28M | $29M | $0 | $3M | $5M | $0 | · | |
| Other Non-current Liabilities | · | · | · | · | $0 | $866.0K | $912.0K | |
| Total Liabilities | $44M | $93M | $39M | $37M | $22M | $12M | $9M | |
| Long-term Debt | $0 | $30M | $10M | $10M | $0 | · | · | |
| Common Stock | $6.0K | $6.0K | $6.0K | $5.0K | $3.0K | $3.0K | $1.0K | |
| Retained Earnings | $-859M | $-710M | $-500M | $-338M | $-215M | $-118M | $-76M | |
| AOCI | $-15.0K | $321.0K | $345.0K | $-2M | $-201.0K | $-32.0K | $-1.0K | |
| Stockholders' Equity | $181M | $304M | $474M | $313M | $199M | $283M | $-76M | |
| Liabilities + Equity | $225M | $397M | $512M | $351M | $221M | $296M | $119M | |
| Shares Outstanding | 61,449,290 | 60,860,838 | 59,921,002 | 48,941,254 | 36,083,301 | 35,552,795 | 1,846,024 |
Cash Flow 8
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $26M | $38M | $44M | $23M | $10M | $4M | $2M | |
| Operating Cash Flow | $-128M | $-156M | $-116M | $-95M | $-75M | $-37M | $-3M | |
| CapEx | $374.0K | $4M | $921.0K | $2M | $2M | $2M | $964.0K | |
| Investing Cash Flow | $134M | $140M | $-127M | $-150M | $74M | $-211M | $-18M | |
| Financing Cash Flow | $-32M | $23M | $274M | $227M | $3M | $213M | $46M | |
| Net Change in Cash | $-26M | $8M | $31M | $-18M | $783.0K | $-35M | $25M | |
| Taxes Paid | $0 | $0 | · | · | · | · | · | |
| Free Cash Flow | $-129M | $-159M | $-117M | $-96M | · | $-39M | · |
Profitability 5
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | -11654.8% | -1313.4% | · | -99.6% | · | |
| Net Margin | · | · | -10211.1% | -1273.3% | · | -99.3% | · | |
| EBITDA Margin | · | · | -11654.8% | -1313.4% | · | -99.6% | · | |
| ROA | -48.0% | -46.3% | -37.4% | -43.1% | · | -20.0% | · | |
| ROE | -74.4% | -64.7% | -33.0% | -37.9% | · | -14.2% | · |
Liquidity & Solvency 3
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.0 | 10.9 | 17.7 | 14.2 | · | 25.1 | · | |
| Quick Ratio | 11.7 | 10.7 | 17.3 | 13.9 | · | 24.7 | · | |
| Interest Coverage | · | · | -145.3 | · | · | · | · |
Efficiency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.0 | 0.0 | · | 0.2 | · | |
| Receivables Turnover | · | · | 1.6 | 4.9 | · | 5.1 | · |
Growth Rates 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Revenue YoY | · | · | -83.7% | 27.9% | -81.9% | · | · | |
| Revenue CAGR 3Y | · | · | -66.4% | · | · | · | · |
Valuation (TTM) 10
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $0 | $2M | $10M | $8M | $42M | · | |
| Net Income TTM | $-149M | $-210M | $-161M | $-123M | $-97M | $-42M | · | |
| Market Cap | $75M | $802M | $1.09B | $946M | · | $808M | · | |
| P/E | -0.5 | -3.8 | -6.6 | -6.6 | -5.0 | -11.7 | · | |
| P/S | · | · | 686.8 | 97.7 | · | 19.3 | · | |
| P/B | 0.4 | 2.6 | 2.3 | 3.0 | · | 2.9 | · | |
| P / Tangible Book | 0.4 | 2.6 | 2.3 | 3.0 | · | 2.9 | · | |
| P / Cash Flow | -0.6 | -5.2 | -9.3 | -10.0 | · | -21.7 | · | |
| P / FCF | -0.6 | -5.0 | -9.3 | -9.8 | · | -20.8 | · | |
| Earnings Yield | -199.2% | -26.4% | -15.2% | -15.2% | -20.1% | -8.6% | · |
Income Statement 13
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $248.0K | $1M | $2M | $1M | |
| R&D Expense | $17M | $14M | $16M | $18M | $32M | $43M | $39M | $48M | $46M | $37M | $33M | $32M | $33M | $29M | $25M | $25M | |
| SG&A Expense | $7M | $8M | $8M | $10M | $13M | $15M | $15M | $14M | $15M | $15M | $14M | $15M | $15M | $14M | $14M | $9M | |
| Operating Expenses | $24M | $22M | $24M | $28M | $46M | $59M | $53M | $62M | $61M | $52M | $47M | $48M | $48M | $43M | $39M | $33M | |
| Operating Income | $-24M | $-22M | $-24M | $-28M | $-46M | $-59M | $-53M | $-62M | $-61M | $-52M | $-47M | $-48M | $-47M | $-42M | $-37M | $-32M | |
| Interest Expense | · | · | · | · | · | · | · | · | · | $445.0K | · | $317.0K | $319.0K | $311.0K | · | $301.0K | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-22M | $-20M | $-24M | $-26M | $-43M | $-56M | $-50M | $-58M | $-56M | $-47M | $-41M | $-41M | $-41M | $-38M | $-35M | $-31M | |
| EPS (Basic) | $-0.36 | $-0.32 | $-0.37 | $-0.43 | $-0.71 | $-0.92 | $-0.82 | $-0.95 | $-0.92 | $-0.78 | $-0.68 | $-0.70 | $-0.70 | $-0.67 | $-0.69 | $-0.65 | |
| EPS (Diluted) | $-0.36 | $-0.32 | $-0.37 | $-0.43 | $-0.71 | $-0.92 | $-0.82 | $-0.95 | $-0.92 | $-0.78 | $-0.68 | $-0.70 | $-0.70 | $-0.67 | $-0.69 | $-0.65 | |
| Shares (Basic) | 61,919,233 | 61,803,467 | -122,648,447 | 61,406,475 | 61,386,183 | 61,222,676 | -120,756,013 | 60,730,935 | 60,382,796 | 60,180,921 | -116,199,840 | 59,688,451 | 59,172,869 | 56,057,603 | -77,072,725 | 46,799,058 | |
| Shares (Diluted) | 61,919,233 | 61,803,467 | -122,648,447 | 61,406,475 | 61,386,183 | 61,222,676 | -120,756,013 | 60,730,935 | 60,382,796 | 60,180,921 | -116,199,840 | 59,688,451 | 59,172,869 | 56,057,603 | -77,072,725 | 46,799,058 | |
| EBITDA | $-24M | $-22M | · | $-28M | $-46M | $-59M | · | $-62M | $-61M | $-52M | · | $-48M | $-47M | $-42M | · | $-32M |
Balance Sheet 22
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $25M | $22M | $45M | $94M | $87M | $92M | $71M | $80M | $80M | $114M | $63M | $58M | $55M | $103M | · | $45M | |
| Short-term Investments | $133M | $149M | $145M | $148M | $176M | $214M | $285M | $325M | $356M | $368M | $431M | $466M | $500M | $475M | · | $316M | |
| Receivables | · | · | · | · | · | · | · | · | · | · | · | $0 | $2M | $3M | · | $1M | |
| Prepaid Expense | $4M | $3M | $4M | $4M | $5M | $6M | $7M | $6M | $11M | $8M | $11M | $11M | $9M | $8M | · | $4M | |
| Current Assets | $163M | $175M | $196M | $246M | $267M | $311M | $362M | $410M | $448M | $490M | $506M | $534M | $566M | $588M | · | $366M | |
| PP&E (Net) | $2M | $3M | $3M | $4M | $5M | $5M | $6M | $6M | $5M | $6M | $4M | $4M | $4M | $4M | · | $5M | |
| PP&E (Gross) | $13M | $13M | $14M | $16M | $17M | $16M | $16M | $16M | $15M | $15M | $12M | $12M | $12M | $11M | · | $11M | |
| Accum. Depreciation | $11M | $10M | $11M | $12M | $12M | $11M | $11M | $10M | $10M | $9M | $9M | $8M | $8M | $7M | · | $6M | |
| Other Non-current Assets | $554.0K | $389.0K | $392.0K | $392.0K | $391.0K | $427.0K | $435.0K | $427.0K | $437.0K | $392.0K | $392.0K | $392.0K | $672.0K | $644.0K | · | $397.0K | |
| Total Assets | $190M | $203M | $225M | $277M | $300M | $345M | $397M | $446M | $484M | $522M | $512M | $540M | $575M | $598M | · | $377M | |
| Accounts Payable | $2M | $362.0K | $480.0K | $485.0K | $1M | $6M | $6M | $7M | $3M | $7M | $5M | $3M | $2M | $1M | · | $3M | |
| Accrued Liabilities | $4M | $4M | $10M | $8M | $7M | $7M | $12M | $10M | $8M | $6M | $10M | $8M | $7M | · | · | $20M | |
| Current Liabilities | $16M | $10M | $16M | $18M | $21M | $28M | $33M | $40M | $31M | $30M | $29M | $27M | $30M | $23M | · | $26M | |
| Capital Leases | $26M | $27M | $28M | $28M | $29M | $29M | $29M | $30M | $30M | $24M | $0 | $0 | $2M | $3M | · | $4M | |
| Total Liabilities | $43M | $37M | $44M | $76M | $80M | $88M | $93M | $100M | $91M | $84M | $39M | $37M | $42M | $36M | · | $40M | |
| Long-term Debt | $0 | $0 | $0 | $30M | $30M | $30M | $30M | $30M | $30M | $30M | $10M | $10M | $10M | $10M | · | $10M | |
| Common Stock | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | · | $5.0K | |
| Retained Earnings | $-902M | $-879M | $-859M | $-836M | $-810M | $-766M | $-710M | $-660M | $-603M | $-547M | $-500M | $-459M | $-417M | $-376M | · | $-303M | |
| AOCI | $-397.0K | $-341.0K | $-15.0K | $34.0K | $-1.0K | $159.0K | $321.0K | $848.0K | $-617.0K | $-489.0K | $345.0K | $-2M | $-2M | $-1M | · | $-2M | |
| Stockholders' Equity | $147M | $165M | $181M | $200M | $220M | $257M | $304M | $346M | $393M | $437M | $474M | $503M | $533M | $562M | $313M | $337M | |
| Liabilities + Equity | $190M | $203M | $225M | $277M | $300M | $345M | $397M | $446M | $484M | $522M | $512M | $540M | $575M | $598M | · | $377M | |
| Shares Outstanding | 61,920,154 | 61,914,569 | 61,449,290 | 61,449,290 | 61,386,183 | 61,386,183 | 60,860,838 | 60,849,503 | 60,425,144 | 60,318,542 | 59,921,002 | 59,890,980 | 59,222,685 | 58,978,902 | 48,941,254 | 48,749,842 |
Cash Flow 7
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $4M | $4M | $5M | $6M | $6M | $9M | $8M | $9M | $11M | $10M | $9M | $10M | $13M | $12M | $11M | $5M | |
| Operating Cash Flow | $-13M | $-19M | $-18M | $-21M | $-41M | $-49M | $-48M | $-32M | $-45M | $-30M | $-25M | $-36M | $-25M | $-30M | $-31M | $-18M | |
| CapEx | $0 | $0 | $0 | $0 | $112.0K | $262.0K | $209.0K | $896.0K | $1M | $1M | $61.0K | $94.0K | $603.0K | $163.0K | $166.0K | $696.0K | |
| Investing Cash Flow | $15M | $-4M | $2M | $28M | $35M | $69M | $39M | $31M | $11M | $60M | $32M | $38M | $-23M | $-174M | $20M | $-178M | |
| Financing Cash Flow | $0 | $74.0K | $-32M | $72.0K | $0 | $498.0K | $102.0K | $543.0K | $684.0K | $22M | $219.0K | $699.0K | $161.0K | $273M | $284.0K | $216M | |
| Net Change in Cash | $3M | $-23M | $-48M | $7M | $-5M | $21M | $-8M | $-770.0K | $-34M | $51M | $7M | $3M | $-48M | $69M | $-11M | $20M | |
| Free Cash Flow | · | $-19M | · | · | · | $-49M | · | · | · | $-32M | · | · | · | $-30M | · | · |
Profitability 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | · | · | · | · | -19083.9% | -3160.3% | · | -2155.7% | |
| Net Margin | · | · | · | · | · | · | · | · | · | · | · | · | -16609.7% | -2818.9% | · | -2065.8% | |
| EBITDA Margin | · | · | · | · | · | · | · | · | · | · | · | · | -19083.9% | -3160.3% | · | -2155.7% | |
| ROA | -9.1% | -7.3% | · | -7.3% | -11.1% | -13.0% | · | -11.7% | -10.5% | -8.4% | · | -9.0% | -10.8% | -9.4% | · | -10.0% | |
| ROE | -12.2% | -9.5% | · | -9.6% | -14.1% | -16.2% | · | -13.6% | -12.1% | -9.4% | · | -9.9% | -12.1% | -10.2% | · | -11.0% |
Liquidity & Solvency 3
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 9.9 | 16.9 | · | 13.9 | 13.0 | 11.0 | · | 10.3 | 14.5 | 16.1 | · | 19.5 | 19.2 | 25.4 | · | 14.0 | |
| Quick Ratio | 9.6 | 16.5 | · | 13.7 | 12.8 | 10.8 | · | 10.1 | 14.1 | 15.9 | · | 19.1 | 18.9 | 25.1 | · | 13.8 | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | -117.7 | · | -150.4 | -148.4 | -135.4 | · | · |
Efficiency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | |
| Receivables Turnover | · | · | · | · | · | · | · | · | · | · | · | 0.0 | 0.1 | 0.6 | · | 1.0 |
Valuation (TTM) 10
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $0 | · | $0 | $0 | $0 | · | $0 | $248.0K | $2M | · | $3M | $8M | $9M | · | $9M | |
| Net Income TTM | $-112M | $-146M | · | $-184M | $-213M | $-217M | · | $-202M | $-185M | $-167M | · | $-151M | $-139M | $-126M | · | $-115M | |
| Market Cap | $71M | $78M | · | $91M | $71M | $83M | · | $682M | $650M | $899M | · | $1.04B | $1.07B | $1.57B | · | $1.02B | |
| P/E | -0.6 | -0.5 | · | -0.5 | -0.3 | -0.4 | · | -3.3 | -3.5 | -5.2 | · | -6.4 | -6.4 | -9.1 | · | -7.0 | |
| P/S | · | · | · | · | · | · | · | · | 2619.2 | 568.8 | · | 339.2 | 133.3 | 173.3 | · | 109.2 | |
| P/B | 0.5 | 0.5 | · | 0.5 | 0.3 | 0.3 | · | 2.0 | 1.7 | 2.1 | · | 2.1 | 2.0 | 2.8 | · | 3.0 | |
| P / Tangible Book | 0.5 | 0.5 | · | 0.5 | 0.3 | 0.3 | · | 2.0 | 1.7 | 2.1 | · | 2.1 | 2.0 | 2.8 | · | 3.0 | |
| P / Cash Flow | · | -4.1 | · | · | · | -1.7 | · | · | · | -29.7 | · | · | · | -51.8 | · | · | |
| P / FCF | · | -4.1 | · | · | · | -1.7 | · | · | · | -28.3 | · | · | · | -51.5 | · | · | |
| Earnings Yield | -159.7% | -188.9% | · | -203.4% | -301.7% | -264.4% | · | -29.9% | -28.8% | -19.1% | · | -15.7% | -15.7% | -11.0% | · | -14.4% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $2M | $10M | $8M |
| Operating Margin % | — | — | -11654.8% | -1313.4% | — |
| Net Income | $-149M | $-210M | $-161M | $-123M | $-97M |
| Diluted EPS | $-2.43 | $-3.47 | $-2.75 | $-2.94 | $-2.71 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Current Ratio | 12.0 | 10.9 | 17.7 | 14.2 | — |
| Quick Ratio | 11.7 | 10.7 | 17.3 | 13.9 | — |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $-129M | $-159M | $-117M | $-96M | — |
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Institutional owners (13F) 101 filers · $54.3M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 16 (+6 vs prior Q) | 12 (-1 vs prior Q) | 16 (-9 vs prior Q) | 23 (-1 vs prior Q) | +1.8M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | $7,001,038 | 6,141,261 | 12.90% | Shares |
| ADAR1 Capital Management, LLC | $6,281,085 | 5,509,724 | 11.57% | Shares |
| Fernwood Investment Management, LLC | $5,602,834 | 425,424 | 10.32% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $2,782,000 | 2,440,351 | 5.13% | Shares |
| TWO SIGMA INVESTMENTS, LP | $2,579,628 | 2,262,832 | 4.75% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $2,336,856 | 2,049,874 | 4.31% | Shares |
| Monaco Asset Management SAM | $2,210,172 | 1,938,747 | 4.07% | Shares |
| Lynx1 Capital Management LP | $2,049,800 | 1,798,070 | 3.78% | Shares |
| BML Capital Management, LLC | $1,762,596 | 1,546,137 | 3.25% | Shares |
| CITADEL ADVISORS LLC | $1,616,545 | 1,418,022 | 2.98% | Shares |
| Prosight Management, LP | $1,562,066 | 1,370,233 | 2.88% | Shares |
| TWO SIGMA ADVISERS, LP | $1,519,632 | 1,245,600 | 2.80% | Shares |
| Peapod Lane Capital LLC | $1,492,275 | 1,309,013 | 2.75% | Shares |
| Woodline Partners LP | $1,478,049 | 1,296,534 | 2.72% | Shares |
| Ikarian Capital, LLC | $1,140,000 | 1,000,000 | 2.10% | Shares |
| Eversept Partners, LP | $1,016,224 | 891,425 | 1.87% | Shares |
| Redmile Group, LLC | $880,224 | 772,126 | 1.62% | Shares |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $733,157 | 643,120 | 1.35% | Shares |
| MILLENNIUM MANAGEMENT LLC | $637,770 | 559,447 | 1.18% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $631,138 | 553,630 | 1.16% | Shares |
| UBS Group AG | $615,643 | 540,038 | 1.13% | Shares |
| Connor, Clark & Lunn Investment Management Ltd. | $611,132 | 536,081 | 1.13% | Shares |
| DAFNA Capital Management LLC | $555,180 | 487,000 | 1.02% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $529,052 | 463,750 | 0.97% | Shares |
| XTX Topco Ltd | $502,562 | 440,844 | 0.93% | Shares |
| Laurion Capital Management LP | $470,587 | 412,796 | 0.87% | Shares |
| TORNO CAPITAL, LLC | $400,647 | 351,445 | 0.74% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $389,596 | 341,751 | 0.72% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $345,420 | 303,000 | 0.64% | Shares |
| Verdad Advisers, LP | $320,731 | 281,343 | 0.59% | Shares |
| ArrowMark Colorado Holdings LLC | $320,555 | 281,189 | 0.59% | Shares |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | $313,500 | 275,000 | 0.58% | Shares |
| STATE STREET CORP | $288,897 | 253,418 | 0.53% | Shares |
| Stonepine Capital Management, LLC | $262,813 | 230,538 | 0.48% | Shares |
| Rangeley Capital, LLC | $256,500 | 225,000 | 0.47% | Shares |
| Congress Wealth Management LLC / DE / | $231,907 | 199,920 | 0.43% | Shares |
| Marquette Asset Management, LLC | $198,930 | 174,500 | 0.37% | Shares |
| HighMark Wealth Management LLC | $189,495 | 166,224 | 0.35% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $175,232 | 153,712 | 0.32% | Shares |
| JANE STREET GROUP, LLC | $148,144 | 129,951 | 0.27% | Shares |
| NORTHERN TRUST CORP | $142,567 | 125,059 | 0.26% | Shares |
| ALGERT GLOBAL LLC | $140,678 | 123,402 | 0.26% | Shares |
| OSAIC HOLDINGS, INC. | $131,013 | 114,924 | 0.24% | Shares |
| Invesco Ltd. | $119,333 | 104,678 | 0.22% | Shares |
| Bond & Devick Financial Network, Inc. | $114,182 | 100,160 | 0.21% | Shares |
| KOTLER KEVIN | $113,460 | 93,000 | 0.21% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $98,175 | 86,118 | 0.18% | Shares |
| MARSHALL WACE, LLP | $94,582 | 82,966 | 0.17% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $93,366 | 81,900 | 0.17% | Put option |
| Cubist Systematic Strategies, LLC | $80,463 | 54,367 | 0.15% | Shares |
| JANE STREET GROUP, LLC | $70,566 | 61,900 | 0.13% | Call option |
| AMERIPRISE FINANCIAL INC | $62,847 | 55,129 | 0.12% | Shares |
| Squarepoint Ops LLC | $46,528 | 40,814 | 0.09% | Shares |
| Headlands Technologies LLC | $38,404 | 33,688 | 0.07% | Shares |
| Quadrature Capital Ltd | $37,939 | 33,280 | 0.07% | Shares |
| GOLDMAN SACHS GROUP INC | $37,508 | 32,902 | 0.07% | Shares |
| TUDOR INVESTMENT CORP ET AL | $33,891 | 29,729 | 0.06% | Shares |
| FEDERATED HERMES, INC. | $33,123 | 29,055 | 0.06% | Shares |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $32,490 | 28,500 | 0.06% | Shares |
| Point72 Asia (Singapore) Pte. Ltd. | $32,419 | 21,905 | 0.06% | Shares |
| Spark Investment Management LLC | $25,764 | 22,600 | 0.05% | Shares |
| Blackstone Inc. | $25,315 | 22,206 | 0.05% | Shares |
| VANGUARD GROUP INC | $23,799 | 19,507 | 0.04% | Shares |
| Point72 Asset Management, L.P. | $22,883 | 20,073 | 0.04% | Shares |
| Vanguard Global Advisers, LLC | $22,238 | 19,507 | 0.04% | Shares |
| Nuveen Asset Management, LLC | $22,020 | 1,672 | 0.04% | Shares |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $20,594 | 18,065 | 0.04% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $17,647 | 15,480 | 0.03% | Shares |
| NewEdge Advisors, LLC | $17,100 | 15,000 | 0.03% | Shares |
| BlackRock, Inc. | $15,894 | 13,942 | 0.03% | Shares |
| AlphaQuest LLC | $14,294 | 11,716 | 0.03% | Shares |
| JANE STREET GROUP, LLC | $13,794 | 12,100 | 0.03% | Put option |
| Fiduciary Trust Co | $13,247 | 11,620 | 0.02% | Shares |
| Qube Research & Technologies Ltd | $11,438 | 10,033 | 0.02% | Shares |
| SIMPLEX TRADING, LLC | $5,614 | 4,925 | 0.01% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $2,747 | 2,416,508 | 0.01% | Shares |
| ROYAL BANK OF CANADA | $1,000 | 445 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $752 | 660 | 0.00% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $749 | 657 | 0.00% | Shares |
| HARBOUR INVESTMENTS, INC. | $672 | 590 | 0.00% | Shares |
| BESSEMER GROUP INC | $601 | 527,309 | 0.00% | Shares |
| FMR LLC | $478 | 419 | 0.00% | Shares |
| Bank of New York Mellon Corp | $388 | 340 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $342 | 300 | 0.00% | Shares |
| CWM, LLC | $267 | 212 | 0.00% | Shares |
| GSA CAPITAL PARTNERS LLP | $185 | 162,206 | 0.00% | Shares |
| Point72 (DIFC) Ltd | $166 | 112 | 0.00% | Shares |
| Truvestments Capital LLC | $57 | 50 | 0.00% | Shares |
| WELLS FARGO & COMPANY/MN | $57 | 50 | 0.00% | Shares |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $41 | 36 | 0.00% | Shares |
| SEI INVESTMENTS CO | $10 | 11 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $9 | 8 | 0.00% | Shares |
| JPMORGAN CHASE & CO | $8 | 7 | 0.00% | Shares |
| COMERICA BANK | $7 | 6 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $6 | 5 | 0.00% | Shares |
| IFG Advisory, LLC | $5 | 4 | 0.00% | Shares |
| Global Retirement Partners, LLC | $5 | 4 | 0.00% | Shares |
| FIFTH THIRD BANCORP | $5 | 4 | 0.00% | Shares |
| BARCLAYS PLC | $1 | 1 | 0.00% | Shares |
| MORGAN STANLEY | $1 | 1 | 0.00% | Shares |
Company insiders 21 insiders · 7 officers · 13 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Bernard Coulie | President and CEO | July 17, 2023 S | 342,103 | 0 | 0 | $0 |
| Keith Lamont Cummings | Chief Financial Officer | July 17, 2023 S | 203,999 | 0 | 0 | $0 |
| Hans Hull | Chief Business Officer | Aug. 4, 2023 M | 194,855 | 0 | 0 | $0 |
| Mike Ouimette | General Counsel & Corp. Sec'y | July 20, 2023 S | 60,443 | 0 | 0 | $0 |
| Eric Lefebvre | Chief Medical Officer | July 17, 2023 S | 167,215 | 0 | 0 | $0 |
| Lily Cheung | Chief Human Resource Officer | Jan. 19, 2023 A | — | 0 | 0 | $0 |
| Barbara Howes | Chief Human Resource Officer | Jan. 23, 2021 A | 24,799 | 0 | 0 | $0 |
| Flavia Borellini | Director | July 9, 2026 A | — | 0 | 0 | $0 |
| Robert Iannone | Director | July 9, 2026 A | — | 0 | 0 | $0 |
| Steve E. Krognes | Director | June 11, 2026 A | — | 0 | 0 | $0 |
| Darren S Cline | Director | June 11, 2026 A | — | 0 | 0 | $0 |
| John T Curnutte | Director | June 11, 2026 A | — | 0 | 0 | $0 |
| Thomas A Mccourt | Director | June 11, 2026 A | — | 0 | 0 | $0 |
| Hoyoung Huh | Director | June 11, 2026 A | 239,619 | 0 | 0 | $0 |
| Gayle A Crowell | Director | June 11, 2026 A | — | 0 | 0 | $0 |
| Smital Shah | Director | June 7, 2023 A | — | 0 | 0 | $0 |
| Katharine Knobil | Director | June 7, 2023 A | — | 0 | 0 | $0 |
| Suzanne Louise Bruhn | Director | June 7, 2023 A | — | 0 | 0 | $0 |
| David E I Pyott | Director | June 7, 2023 A | — | 0 | 0 | $0 |
| Neil Exter | — | June 29, 2021 A | 0 | 0 | 0 | $0 |
| Charles J Homcy | — | June 29, 2021 A | — | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 1 position
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT, LLC, KEVIN TANG, TANG CAPITAL PARTNERS, LP, TANG CAPITAL PARTNERS INTERNATIONAL, LP, TANG CAPITAL PARTNERS III, INC, TANG CAPITAL PARTNERS IV, INC, CONCENTRA BIOSCIENCES, LLC | March 10, 2025 | 9.60% | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 5 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| IWC · iShares Trust | 0.01% | 206,605 SH | Aug. 8, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.00% | 104,218 SH | Aug. 8, 2026 | Daily |
| VXF · VANGUARD INDEX FUNDS | 0.00% | 615,799 SH | Aug. 8, 2026 | Daily |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 1,746,470 SH | Aug. 8, 2026 | Daily |
| VHT · VANGUARD WORLD FUND | 0.00% | 153,712 SH | Aug. 8, 2026 | Daily |