NKTR Nektar Therapeutics - Common Stock

NASDAQ · Pharmaceuticals · View on SEC EDGAR ↗
$75.92
Price · Aug 19, 2026
Fundamentals as of Aug 14, 2026

About Nektar Therapeutics - Common Stock Company overview from Wikipedia

Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances, which improves drug characteristics like retention and solubility. It is a technology supplier to a number of pharmaceutical companies including Affymax, Amgen, Merck, Pfizer and UCB Pharma, etc. The company developed the world's first inhalable non-injectable insulin, Exubera, which was awarded as the bronze award by Wall Street Journal for its technological breakthrough.

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Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances, which improves drug characteristics like retention and solubility. It is a technology supplier to a number of pharmaceutical companies including Affymax, Amgen, Merck, Pfizer and UCB Pharma, etc. The company developed the world's first inhalable non-injectable insulin, Exubera, which was awarded as the bronze award by Wall Street Journal for its technological breakthrough.

Background

The company is engaged in developing a proprietary pipeline of drug candidates for several therapeutic areas including oncology, pain, anti-infectives, anti-viral and immunology. The company's research and development involve in small molecule and biologic drug candidates. Its drug candidate base consists of naloxegol (Movantik), a Phase III oral opioid antagonist, etirinotecan pegol, a topoisomerase inhibitor under Phase III clinical study as of 2012, NKTR 061, NKTR-181, NKTR-214, etc.

In 2013, the company was assigned a patent which was developed by the company and other four co-inventors. The products of the company is served as a supplement to improve the pharmacokinetics, pharmacodynamics, half-life, bioavailability and other areas of drugs for the patients worldwide. As of March 2014, the company had a market capitalization of $1.7 billion with an enterprise value of $1.67 billion.

As of December 2024, at a stock price-per-share of roughly $1, the market cap is roughly $171 million. Nektar underwent periods of downsizing after unsuccessful partnerships were ended with Eli Lilly in 2023 and Bristol Myers Squibb in 2022, resulting in layoffs of most company employees.

Pipeline

Etirinotecan pegol was in the phase III BEACON trial as well as in the I-SPY2 adaptive clinical trial for breast cancer in 2016. The European Medicines Agency refused a marketing authorisation in 2017.

Bempegaldesleukin (NKTR-214) is a CD122-biased immune-stimulatory cytokine, Phase I results were announced in November 2016. It is now in a phase 2 trial in combination with nivolumab for various advanced cancers.

In 2023 Nektar's partnership with Eli Lilly in development of "rezpeg" was ended. Eli Lilly claimed the drug lacked suitable efficacy, while Nektar responded that Eli Lilly had botched the analysis.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

NKTR Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$75.92
Market Cap
$2.24B
P/E (TTM)
-11.3
EPS (TTM)
$-9.73
Revenue (TTM)
$55M
Div Yield
ROE
-500.1%
Debt/Equity
52W Range
$25 – $109

NKTR Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $55M
10-point trend, -66.6%
2016-12-31 2025-12-31
EPS $-9.73
10-point trend, -784.5%
2016-12-31 2025-12-31
Free Cash Flow $-209M
10-point trend, -69.1%
2016-12-31 2025-12-31
Margins -297.1%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
NKTR
Peer Median
P/E (TTM)
5-point trend, +93.9%
-11.3
29.4
P/S (TTM)
5-point trend, -95.8%
40.5
4.9
P/B
5-point trend, -82.7%
24.9
6.5
Price / FCF
5-point trend, +95.3%
-10.7

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
NKTR
Peer Median
Operating Margin
5-point trend, +42.1%
-253.7%
Net Profit Margin
5-point trend, +42.2%
-297.1%
-9.0%
ROA
5-point trend, -42.4%
-56.2%
-8.2%
ROE
5-point trend, -606.9%
-500.1%
-19.4%
ROIC
5-point trend, -137.1%
-155.8%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
NKTR
Peer Median
Current Ratio
5-point trend, -46.7%
5.0
3.6
Quick Ratio
5-point trend, -49.6%
0.3

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
NKTR
Peer Median
Revenue YoY
5-point trend, -45.8%
-43.9%
Revenue CAGR 3Y
5-point trend, -45.8%
-15.7%
Revenue CAGR 5Y
5-point trend, -45.8%
-18.4%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
NKTR
Peer Median
EPS (Diluted)
5-point trend, -240.2%
$-9.73

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
NKTR
Peer Median

NKTR Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 17 analysts
  • Strong Buy 7 41.2%
  • Buy 8 47.1%
  • Hold 2 11.8%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

9 analysts · 2026-08-16
Median target $151.00 +98.9%
Mean target $153.22 +101.8%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.21%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-1.23 $-2.02 0.79%
March 31, 2026 $-1.82 $-1.63 -0.19%
Dec. 31, 2025 $-1.78 $-2.52 0.74%
Sept. 30, 2025 $-1.87 $-2.74 0.87%
June 30, 2025 $-2.95 $-3.10 0.15%
March 31, 2025 $-3.60 $-2.51 -1.1%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
NKTR $862M -4.3 -43.9% -297.1% -500.1%
ALMS -3.4 -1011.8% -61.9%
TARS $3.48B -51.5 146.7% -14.7% -19.7%
SUPN $2.86B -73.1 8.6% -5.4% -3.6%
ATAI $223M -1.4 -1.9% -48464.0% -83.1%
TRVI $1.61B -39.1 -22.4%
AMRX 57.3 8.1% 2.4% -80.0% 36.9%
AMLX $1.33B -7.9 -77.1% -61.2%
PBH $3.33B 15.2 -4.3% 17.5% 10.2% 54.7%
RAPP $1.45B -10.6 -29.8%
OCUL $2.62B -8.5 -18.5% -511.9% -55.4%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 17
Annual Income Statement data for NKTR
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, -72.5% $55M $98M $90M $92M $102M $153M $115M $1.19B $308M $165M $231M $201M
Cost of Revenue 12-point trend, -100.0% $0 $31M $34M $22M $25M $19M $21M $24M $31M $30M $34M $29M
R&D Expense 12-point trend, -20.6% $117M $121M $114M $218M $400M $409M $435M $400M $268M $204M $183M $148M
SG&A Expense 12-point trend, +67.8% $69M $77M $77M $92M $123M $105M $99M $81M $52M $44M $43M $41M
Operating Expenses 12-point trend, -10.1% $195M $204M $354M $468M $548M $578M $555M $505M $367M $278M $260M $217M
Operating Income 12-point trend, -749.9% $-140M $-105M $-264M $-376M $-446M $-425M $-440M $688M $-60M $-113M $-29M $-16M
Interest Expense 9-point trend, -100.0% · · · $0 $0 $7M $21M $22M $22M $22M $18M $18M
Interest Income 5-point trend, +282.2% $10M $14M $19M $7M $3M · · · · · · ·
Other Non-op 12-point trend, -55.7% $361.0K $-390.0K $-6M $-116.0K $-162.0K $18M $46M $38M $5M $2M $2M $814.0K
Pretax Income 12-point trend, -201.7% $-164M $-119M $-276M $-365M $-523M $-444M $-440M $683M $-96M $-153M $-81M $-54M
Income Tax 12-point trend, +73.0% $-138.0K $-239.0K $-200.0K $3M $557.0K $493.0K $613.0K $1M $616.0K $876.0K $506.0K $-512.0K
Net Income 12-point trend, -204.3% $-164M $-119M $-276M $-368M $-524M $-444M $-441M $681M $-97M $-154M $-81M $-54M
EPS (Basic) 10-point trend, -784.5% $-9.73 $-8.68 $-1.45 $-1.97 $-2.86 $-2.49 $-2.52 $4.02 $-0.62 $-1.10 · ·
EPS (Diluted) 10-point trend, -784.5% $-9.73 $-8.68 $-1.45 $-1.97 $-2.86 $-2.49 $-2.52 $3.78 $-0.62 $-1.10 · ·
Shares (Basic) 10-point trend, -87.9% 16,870,930 13,710,775 190,001,000 187,138,000 183,298,000 178,581,000 174,993,000 169,600,000 155,953,000 139,596,000 · ·
Shares (Diluted) 10-point trend, -87.9% 16,870,930 13,710,775 190,001,000 187,138,000 183,298,000 178,581,000 174,993,000 180,119,000 155,953,000 139,596,000 · ·
EBITDA 11-point trend, -377.0% $-140M $-101M $-257M $-364M $-433M $-413M $-429M $697M $-47M $-113M $-29M ·
Balance Sheet 24
Annual Balance Sheet data for NKTR
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +22.2% $15M $44M $35M $88M $25M $199M $96M $195M $5M $60M $56M $12M
Short-term Investments 4-point trend, +29.2% · · · · · · · · $291M $329M $253M $225M
Receivables 11-point trend, -100.0% · $0 $1M $6M $22M $39M $37M $43M $5M $16M $20M $4M
Inventory 12-point trend, -100.0% $0 $0 $16M $19M $16M $15M $13M $11M $11M $11M $11M $13M
Other Current Assets 12-point trend, +132.7% $21M $6M $10M $16M $23M $22M $15M $21M $8M $10M $10M $9M
Current Assets 12-point trend, -7.6% $266M $261M $331M $546M $796M $1.14B $1.42B $1.44B $327M $426M $350M $288M
PP&E (Net) 12-point trend, -97.1% $2M $3M $19M $32M $61M $60M $66M $49M $47M $66M $71M $70M
Accum. Depreciation 11-point trend, -83.0% · $16M $87M $125M $148M $138M $128M $121M $115M $111M $103M $94M
Goodwill 10-point trend, -100.0% · · $0 $77M $77M $77M $77M $77M $77M $77M $77M $77M
Other Non-current Assets 12-point trend, +115.8% $14M $5M $5M $2M $3M $1M $344.0K $4M $994.0K $817.0K $754.0K $7M
Total Assets 12-point trend, -36.5% $280M $304M $398M $711M $1.12B $1.54B $1.98B $2.15B $509M $569M $499M $442M
Accounts Payable 12-point trend, +298.4% $11M $12M $10M $13M $10M $22M $19M $6M $5M $3M $2M $3M
Accrued Liabilities 5-point trend, +247.0% $22M $30M $22M $37M · · · · · · · $6M
Current Liabilities 12-point trend, -16.4% $54M $61M $51M $68M $85M $116M $354M $82M $56M $72M $61M $64M
Capital Leases 11-point trend, +1476.6% $65M $83M $99M $113M $126M $136M $143M $0 · $2M $1M $4M
Other Non-current Liabilities 12-point trend, -41.4% $9M $7M $5M $8M $4M $9M $768.0K $10M $6M $7M $10M $15M
Total Liabilities 12-point trend, -53.0% $191M $243M $267M $344M $438M $461M $572M $433M $421M $481M $492M $405M
Common Stock 12-point trend, -84.6% $2.0K $1.0K $19.0K $19.0K $19.0K $18.0K $17.0K $17.0K $15.0K $15.0K $13.0K $13.0K
Retained Earnings 12-point trend, -110.5% $-3.76B $-3.60B $-3.48B $-3.20B $-2.83B $-2.31B $-1.86B $-1.42B $-2.12B $-2.02B $-1.87B $-1.79B
Treasury Stock 2-point trend, +3000000.00 · $3M $0 · · · · · · · · ·
AOCI 12-point trend, +101.1% $17.0K $61.0K $80.0K $-7M $-4M $-2M $-1M $-6M $-2M $-2M $-2M $-2M
Stockholders' Equity 12-point trend, +147.3% $90M $61M $131M $367M $680M $1.08B $1.41B $1.72B $88M $88M $6M $36M
Liabilities + Equity 12-point trend, -36.5% $280M $304M $398M $711M $1.12B $1.54B $1.98B $2.15B $509M $569M $499M $442M
Shares Outstanding 12-point trend, -84.5% 20,378,832 12,385,001 12,757,984 188,560,000 185,468,000 180,091,000 176,505,000 173,530,000 159,524,000 153,212,000 135,289,000 131,216,000
Cash Flow 14
Annual Cash Flow data for NKTR
Metric Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, -92.1% $1M $4M $7M $12M $13M $12M $11M $9M $13M $13M $11M $13M
Stock-based Comp · · · · · · · · · · · $17M
Deferred Tax 12-point trend, +306.5% $64.0K $-10.0K $-140.0K $3M $-102.0K $-36.0K $-21.0K $93.0K $35.0K $-115.0K $-22.0K $-31.0K
Other Non-cash 8-point trend, -1770.0% · $-61M $77M $49M $98M $119M $101M $28M $4M · · ·
Operating Cash Flow 12-point trend, -46.8% $-209M $-176M $-193M $-304M $-413M $-313M $-329M $718M $-80M $-117M $-73M $-142M
CapEx 12-point trend, -98.3% $171.0K $1M $865.0K $6M $15M $7M $26M $14M $10M $6M $11M $10M
Investing Cash Flow 10-point trend, +98.5% $-1M $143M $140M $366M $203M $496M $207M $-1.38B $-29M $-82M · ·
Stock Repurchased 3-point trend, +0.00 $0 $3M $0 · · · · · · · · ·
Net Stock Activity 2-point trend, +100.0% $0 $-3M · · · · · · · · · ·
Financing Cash Flow 10-point trend, -11.3% $181M $42M $30.0K $2M $36M $-80M $23M $852M $54M $204M · ·
Net Change in Cash 12-point trend, -9.1% $-29M $9M $-53M $63M $-174M $103M $-99M $190M $-55M $4M $43M $-27M
Taxes Paid 12-point trend, -120.2% $-195.0K $76.0K $3M $272.0K $325.0K $539.0K $555.0K $618.0K $556.0K $757.0K $860.0K $964.0K
Free Cash Flow 11-point trend, -147.6% $-209M $-177M $-193M $-310M $-428M $-321M $-355M $704M $-90M $-123M $-84M ·
Levered FCF 8-point trend, -201.6% · · · $-310M $-428M $-327M $-376M $682M $-112M $-146M $-103M ·
Profitability 7
Annual Profitability data for NKTR
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, -1892.6% -253.7% -106.9% -292.6% -408.6% -437.8% -278.0% -383.9% 57.6% -19.4% -68.2% -12.7% ·
Net Margin 11-point trend, -744.7% -297.1% -120.9% -306.3% -400.0% -514.0% -290.6% -384.5% 57.1% -31.4% -92.8% -35.2% ·
Pretax Margin 11-point trend, -750.5% -297.3% -121.1% -306.5% -396.5% -513.5% -290.3% -383.9% 57.2% -31.2% -92.3% -35.0% ·
EBITDA Margin 11-point trend, -1892.6% -253.7% -102.7% -284.8% -395.4% -425.0% -269.8% -374.3% 58.4% -15.3% -68.2% -12.7% ·
ROA 11-point trend, -226.6% -56.2% -33.9% -49.8% -40.3% -39.5% -25.3% -21.3% 51.2% -17.9% -28.8% -17.2% ·
ROE 11-point trend, -31.7% -500.1% -217.0% -190.2% -94.5% -70.7% -39.5% -30.4% 38.9% -109.9% -324.7% -379.7% ·
ROIC 11-point trend, +66.1% -155.8% -172.9% -201.2% -103.5% -65.7% -39.5% -31.4% 40.0% -68.3% -128.8% -459.7% ·
Liquidity & Solvency 3
Annual Liquidity & Solvency data for NKTR
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -13.0% 5.0 4.3 6.5 8.0 9.3 9.8 4.0 17.5 5.8 5.9 5.7 ·
Quick Ratio 11-point trend, -94.7% 0.3 0.7 0.7 1.4 0.6 2.1 0.4 2.9 5.4 5.6 5.4 ·
Interest Coverage 6-point trend, -3762.2% · · · · · -62.1 -20.6 31.9 -2.7 -5.0 -1.6 ·
Efficiency 3
Annual Efficiency data for NKTR
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, -61.3% 0.2 0.3 0.2 0.1 0.1 0.1 0.1 0.9 0.6 0.3 0.5 ·
Inventory Turnover 10-point trend, +35.8% · 3.8 1.9 1.2 1.6 1.4 1.8 2.2 2.8 2.7 2.8 ·
Receivables Turnover 10-point trend, +733.7% · 163.4 25.1 6.5 3.3 4.0 2.9 49.5 29.7 9.3 19.6 ·
Per Share 5
Annual Per Share data for NKTR
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, +9180.2% $4.41 $0.33 $0.68 $1.94 $3.66 $5.98 $7.96 $9.90 $0.55 $0.58 $0.05 ·
Revenue / Share 8-point trend, -50.6% $3.27 $0.48 $0.47 $0.49 $0.56 $0.86 $0.66 $6.63 · · · ·
Cash Flow / Share 8-point trend, -410.0% $-12.36 $-0.85 $-1.01 $-1.62 $-2.25 $-1.75 $-1.88 $3.99 · · · ·
Cash / Share 11-point trend, +80.6% $0.74 $0.24 $0.18 $0.47 $0.14 $1.10 $0.55 $1.12 $0.03 $0.39 $0.41 ·
EPS (TTM) 12-point trend, -2062.2% $-9.73 $-8.68 $-1.45 $-1.97 $-2.86 $-2.49 $-2.52 $3.78 $-0.62 $-1.10 $-0.61 $-0.45
Growth Rates 3
Annual Growth Rates data for NKTR
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -31.6% -43.9% 9.2% -2.1% -9.7% -33.4% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +3.1% -15.7% -1.1% -16.2% · · · · · · · · ·
Revenue CAGR 5Y -18.4% · · · · · · · · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for NKTR
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -72.5% $55M $98M $90M $92M $102M $153M $115M $1.19B $308M $165M $231M $201M
Net Income TTM 12-point trend, -204.3% $-164M $-119M $-276M $-368M $-524M $-444M $-441M $681M $-97M $-154M $-81M $-54M
Market Cap 11-point trend, -97.5% $862M $2.59B $1.61B $6.39B $37.59B $45.92B $57.16B $85.56B $142.90B $28.20B $34.19B ·
P/E 12-point trend, +99.2% -4.3 -1.6 -5.8 -17.2 -70.9 -102.4 -128.5 130.4 -1444.8 -167.3 -414.3 -516.7
P/S 11-point trend, -89.5% 15.6 26.3 17.8 69.4 368.8 300.3 498.7 71.7 464.4 170.5 148.2 ·
P/B 11-point trend, -99.8% 9.6 42.7 12.3 17.4 55.3 42.6 40.7 49.8 1627.1 320.0 5318.8 ·
P / Tangible Book 6-point trend, -79.1% 9.6 42.7 12.3 22.0 62.3 45.9 · · · · · ·
P / Cash Flow 11-point trend, +99.1% -4.1 -14.7 -8.3 -21.0 -91.1 -146.6 -173.9 119.1 -1777.1 -241.0 -467.9 ·
P / FCF 11-point trend, +99.0% -4.1 -14.6 -8.3 -20.6 -87.9 -143.3 -161.0 121.5 -1586.2 -228.5 -405.7 ·
Earnings Yield 12-point trend, -12010.5% -23.0% -62.2% -17.3% -5.8% -1.4% -0.98% -0.78% 0.77% -0.07% -0.60% -0.24% -0.19%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $55M$98M$90M$92M$102M
Operating Margin % -253.7%-106.9%-292.6%-408.6%-437.8%
Net Income $-164M$-119M$-276M$-368M$-524M
Diluted EPS $-9.73$-8.68$-1.45$-1.97$-2.86
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 5.04.36.58.09.3
Quick Ratio 0.30.70.71.40.6
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-209M$-177M$-193M$-310M$-428M

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 269 filers · $2.1B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
88 (+20 vs prior Q) 41 (+9 vs prior Q) 91 (+21 vs prior Q) 48 (-8 vs prior Q) +8.5M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Two Seas Capital LP $215,868,856 3,092,234 10.35% Shares
FMR LLC $192,088,149 2,751,585 9.21% Shares
BVF INC/IL $166,920,946 2,391,075 8.00% Shares
VANGUARD CAPITAL MANAGEMENT LLC $104,495,029 1,496,849 5.01% Shares
TWO SIGMA INVESTMENTS, LP $83,911,899 1,202,004 4.02% Shares
Vestal Point Capital, LP $69,810,000 1,000,000 3.35% Shares
STATE STREET CORP $63,504,691 909,679 3.04% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $57,502,497 823,700 2.76% Call option
Prosight Management, LP $56,546,100 810,000 2.71% Shares
GEODE CAPITAL MANAGEMENT, LLC $52,759,799 755,586 2.53% Shares
ARMISTICE CAPITAL, LLC $50,542,440 724,000 2.42% Shares
GILDER GAGNON HOWE & CO LLC $41,946,944 600,873 2.01% Shares
MILLENNIUM MANAGEMENT LLC $33,377,557 478,120 1.60% Shares
BRAIDWELL LP $33,063,203 473,617 1.59% Shares
Sofinnova Investments, Inc. $32,933,775 471,763 1.58% Shares
Woodline Partners LP $32,871,784 470,875 1.58% Shares
ORBIMED ADVISORS LLC $32,485,804 465,346 1.56% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $27,540,045 394,500 1.32% Put option
EMERALD ADVISERS, LLC $27,236,930 390,158 1.31% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $24,331,577 348,540 1.17% Shares
DAFNA Capital Management LLC $22,226,108 318,380 1.07% Shares
Deep Track Capital, LP $20,943,000 300,000 1.00% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $19,893,826 284,971 0.95% Shares
22NW, LP $19,624,638 281,115 0.94% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $19,475,384 278,977 0.93% Shares
PRIMECAP MANAGEMENT CO/CA/ $19,047,658 272,850 0.91% Shares
Nearwater Capital Markets, Ltd $18,255,315 261,500 0.88% Shares
BARCLAYS PLC $17,968,815 257,396 0.86% Shares
EMERALD MUTUAL FUND ADVISERS TRUST $17,842,528 255,587 0.86% Shares
ADAR1 Capital Management, LLC $17,046,485 244,184 0.82% Shares
Creek Drive Management Group LLC $16,963,830 243,000 0.81% Shares
SEVEN GRAND MANAGERS, LLC $16,754,400 240,000 0.80% Shares
VANGUARD FIDUCIARY TRUST CO $16,724,731 239,575 0.80% Shares
NORGES BANK $15,030,093 215,300 0.72% Shares
Bronte Capital Management Pty Ltd. $13,852,678 198,434 0.66% Shares
TWO SIGMA ADVISERS, LP $13,039,744 308,414 0.63% Shares
CITADEL ADVISORS LLC $12,251,655 175,500 0.59% Put option
GREAT POINT PARTNERS LLC $12,216,750 175,000 0.59% Shares
Caption Management, LLC $11,944,491 171,100 0.57% Call option
MILLENNIUM MANAGEMENT LLC $11,867,700 170,000 0.57% Call option
CITADEL ADVISORS LLC $11,434,878 163,800 0.55% Call option
AMERIPRISE FINANCIAL INC $11,050,085 158,288 0.53% Shares
Quinn Opportunity Partners LLC $10,686,236 153,076 0.51% Shares
GOLDMAN SACHS GROUP INC $10,011,801 143,415 0.48% Shares
Rhenman & Partners Asset Management AB $9,860,662 141,250 0.47% Shares
Qube Research & Technologies Ltd $9,111,671 130,521 0.44% Shares
LMR Partners LLP $9,075,300 130,000 0.44% Put option
Soleus Capital Management, L.P. $8,960,951 128,362 0.43% Shares
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. $8,570,364 122,767 0.41% Shares
Stonepine Capital Management, LLC $8,422,856 120,654 0.40% Shares
SummitTX Capital, L.P. $7,883,923 112,934 0.38% Shares
APEIRON CAPITAL Ltd $7,429,948 106,431 0.36% Shares
CITIGROUP INC $7,034,824 100,771 0.34% Shares
ING GROEP NV $6,981,000 100,000 0.33% Shares
LMR Partners LLP $6,981,000 100,000 0.33% Shares
Susquehanna Portfolio Strategies, LLC $6,685,704 95,770 0.32% Shares
Militia Capital Management LLC $6,282,900 90,000 0.30% Shares
ACT CAPITAL MANAGEMENT, LLC $6,234,033 89,300 0.30% Shares
Tetragon Partners GP Ltd $6,073,191 86,996 0.29% Shares
READYSTATE ASSET MANAGEMENT LP $5,941,529 85,110 0.28% Shares
Birchview Capital, LP $5,654,610 81,000 0.27% Shares
BlackRock, Inc. $5,444,412 77,989 0.26% Shares
GROUP ONE TRADING LLC $4,912,600 70,371 0.24% Shares
ALGERT GLOBAL LLC $4,686,345 67,130 0.22% Shares
Moody Aldrich Partners LLC $4,477,264 64,135 0.21% Shares
WOLVERINE TRADING, LLC $4,330,620 73,500 0.21% Put option
Swiss National Bank $4,300,296 61,600 0.21% Shares
F/m Investments LLC $4,229,439 60,585 0.20% Shares
BANK OF AMERICA CORP /DE/ $4,227,764 60,561 0.20% Shares
ExodusPoint Capital Management, LP $4,084,374 58,507 0.20% Shares
Trexquant Investment LP $3,956,831 56,680 0.19% Shares
K2 PRINCIPAL FUND, L.P. $3,522,962 50,465 0.17% Shares
WOLVERINE TRADING, LLC $3,403,101 57,758 0.16% Shares
RHUMBLINE ADVISERS $3,008,381 43,094 0.14% Shares
MORGAN STANLEY $2,943,050 42,158 0.14% Shares
Voleon Capital Management LP $2,850,901 40,838 0.14% Shares
Anson Funds Management LP $2,829,748 40,535 0.14% Shares
Atom Investors LP $2,828,631 40,519 0.14% Shares
WOLVERINE TRADING, LLC $2,792,808 47,400 0.13% Call option
Burkehill Global Management, LP $2,792,400 40,000 0.13% Shares
NOMURA HOLDINGS INC $2,792,400 40,000 0.13% Put option
IRIDIAN ASSET MANAGEMENT LLC/CT $2,708,768 38,802 0.13% Shares
NOMURA HOLDINGS INC $2,698,645 38,657 0.13% Shares
Jefferies Financial Group Inc. $2,664,299 38,165 0.13% Shares
ALLIANCEBERNSTEIN L.P. $2,590,200 36,000 0.12% Shares
Connor, Clark & Lunn Investment Management Ltd. $2,575,780 36,897 0.12% Shares
ALPS ADVISORS INC $2,386,664 34,188 0.11% Shares
FRED ALGER MANAGEMENT, LLC $2,350,712 33,673 0.11% Shares
TUDOR INVESTMENT CORP ET AL $2,345,616 33,600 0.11% Call option
Bank of New York Mellon Corp $2,306,522 33,040 0.11% Shares
Ghisallo Capital Management LLC $2,233,920 32,000 0.11% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $2,063,670 28,682 0.10% Shares
Blackstone Inc. $2,002,011 28,678 0.10% Shares
KVP Capital Advisors, LP $1,877,889 26,900 0.09% Shares
Ishara Investments LP $1,860,437 26,650 0.09% Shares
Erste Asset Management GmbH $1,830,920 28,000 0.09% Shares
Caption Management, LLC $1,822,041 26,100 0.09% Put option
WINTON GROUP Ltd $1,808,079 25,900 0.09% Shares
K2 PRINCIPAL FUND, L.P. $1,745,250 25,000 0.08% Call option
Empowered Funds, LLC $1,636,416 23,441 0.08% Shares

Company insiders 40 insiders · 20 officers · 18 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Howard W Robin President & CEO July 24, 2026 A 55,045 0 20 $-2,224,055
Jillian B. Thomsen Chief Financial Officer Feb. 16, 2023 S 313,497 0 0 $0
Gil M Labrucherie SVP, COO & CFO May 16, 2022 S 312,905 0 0 $0
Timothy Harkness SVP & Chief Financial Officer Aug. 23, 2007 A 0 0 $0
Louis Drapeau Sr. VP Finance, CFO May 14, 2007 A 6,000 0 0 $0
Milton J Harris President of Nektar AL March 4, 2004 S 743,904 0 0 $0
John Nicholson SVP & Chief Operating Officer Aug. 16, 2019 S 162,759 0 0 $0
Bharat M Chowrira Chief Operating Officer Feb. 1, 2010 A 0 0 $0
Jonathan Zalevsky Chief R&D Officer July 24, 2026 A 9,756 0 12 $-1,052,364
Mark Andrew Wilson Chief Legal Officer Nov. 21, 2025 A 21,585 0 2 $-52,171
John Northcott SVP & Chief Commercial Officer May 16, 2022 S 223,210 0 0 $0
Stephen K Doberstein SVP & Chief Scientific Officer Sept. 5, 2019 P 107,668 0 0 $0
Maninder Hora SVP Pharma Dev & Mfg Ops May 16, 2019 S 94,694 0 0 $0
Ivan P. Gergel SVP & Chief Medical Officer Nov. 15, 2017 A 56,553 0 0 $0
Robert Medve SVP & Chief Medical Officer Feb. 5, 2014 A 0 0 $0
Rinko Ghosh Chief Business Officer Feb. 6, 2013 A 9,753 0 0 $0
Randall W Moreadith SVP Drug Development Feb. 23, 2009 A 0 0 $0
John Stuart Patton Chief Scientific Officer Nov. 14, 2008 M 313,880 0 0 $0
Nevan C Elam SVP & Head of Pulmonary Bus Feb. 25, 2008 A 1,400 0 0 $0
David Johnston SVP, Research & Development May 14, 2007 D 6,600 0 0 $0
Diana Brainard Director Sept. 30, 2025 A 28,560 0 0 $0
Jeffrey Robert Ajer Director Sept. 30, 2025 A 34,153 0 0 $0
Robert Chess Director Sept. 30, 2025 A 255,273 0 0 $0
Scott R Greer Director Sept. 30, 2025 A 303,574 0 0 $0
Roy A Whitfield Director Sept. 30, 2025 A 216,250 0 0 $0
Myriam Curet Director Sept. 19, 2023 A 27,418 0 0 $0
Karin Eastham Director Sept. 16, 2022 A 23,233 0 0 $0
Lutz Lingnau Director Sept. 22, 2020 A 35,800 0 0 $0
Christopher A Kuebler Director Sept. 27, 2018 A 45,250 0 0 $0
Dennis L Winger Director Aug. 21, 2018 M 42,750 0 0 $0
Joseph J Krivulka Director Sept. 19, 2017 A 82,000 0 0 $0
Susan Wang Director Nov. 20, 2015 M 20,000 0 0 $0
BROWN MICHAEL A/CA Director Sept. 15, 2009 A 10,000 0 0 $0
Hoyoung Huh Director Dec. 2, 2008 A 0 0 $0
Irwin Lerner Director Dec. 2, 2008 A 10,000 0 0 $0
James B Glavin Director Sept. 4, 2003 A 0 0 $0
Masuoka K. Lorianne Feb. 8, 2011 A 0 0 $0
Ajit Gill President & CEO March 23, 2006 S 87,991 0 0 $0
Ajay Bansal March 10, 2006 S 5,166 0 0 $0
Melvin Perelman Sept. 2, 2004 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Nektar Therapeutics ( Aug. 22, 2005 Initial filing M&A / sale SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 28 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
LFSC · RBB Fund, Inc. 3.14% 50,876 NS May 31, 2026 N-PORT
SPIT · RBB Fund, Inc. 3.11% 10,455 NS April 30, 2026 N-PORT
PILL · Direxion Shares ETF Trust 1.55% 2,353 NS April 30, 2026 N-PORT
BBC · ETFis Series Trust I 1.15% 5,045 NS April 30, 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0.58% 1,726 SH Aug. 8, 2026 Daily
IHE · iShares Trust 0.55% 120,730 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.16% 59,612 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.14% 278,376 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.13% 33,135 SH Aug. 8, 2026 Daily
TMFX · RBB Fund, Inc. 0.09% 455 NS May 31, 2026 N-PORT
IWM · iShares Trust 0.08% 877,973 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.07% 198,365 SH Aug. 8, 2026 Daily
ISCV · iShares Trust 0.07% 6,414 SH Aug. 8, 2026 Daily
SCHA · SCHWAB STRATEGIC TRUST 0.04% 151,830 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.03% 11,131 NS April 30, 2026 N-PORT
ISCB · iShares Trust 0.03% 1,294 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.03% 387,471 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.03% 92,340 SH Aug. 8, 2026 Daily
WSML · iShares Trust 0.02% 1,887 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.02% 3,096 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.02% 32,466 SH Aug. 8, 2026 Daily
ONEQ · Fidelity Commonwealth Trust 0.00% 6,903 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 48,124 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 9,139 SH Aug. 8, 2026 Daily
TILT · FlexShares Trust 0.00% 770 NS April 30, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 18,540 NS May 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 1,075,430 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 2,837 SH Aug. 8, 2026 Daily