CTMX CytomX Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$3.52
Price · Aug 19, 2026
Fundamentals as of Aug 6, 2026

CTMX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$3.52
Market Cap
$599M
P/E (TTM)
EPS (TTM)
Revenue (TTM)
$76M
Div Yield
ROE
-15.9%
Debt/Equity
52W Range
$2 – $8

CTMX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $76M
10-point trend, +406.6%
2016-12-31 2025-12-31
EPS
Free Cash Flow $-76M
7-point trend, +4.4%
2018-12-31 2025-12-31
Margins -22.8%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
CTMX
Peer Median
P/S (TTM)
5-point trend, +106.0%
7.9
26.1
P/B
5-point trend, +15.4%
6.1
3.0
Price / FCF
5-point trend, -108.9%
-7.9

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
CTMX
Peer Median
Operating Margin
5-point trend, +39.4%
-29.3%
Net Profit Margin
5-point trend, +30.5%
-22.8%
-130.5%
ROA
5-point trend, -35.9%
-12.8%
-28.0%
ROE
5-point trend, +76.4%
-15.9%
-36.6%
ROIC
5-point trend, +66.6%
-22.9%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
CTMX
Peer Median
Current Ratio
5-point trend, -3.8%
3.1
10.4
Quick Ratio
5-point trend, -83.5%
0.3

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
CTMX
Peer Median
Revenue YoY
5-point trend, +104.2%
-44.8%
Revenue CAGR 3Y
5-point trend, +104.2%
12.8%
Revenue CAGR 5Y
5-point trend, +104.2%
2.2%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
CTMX
Peer Median

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
CTMX
Peer Median

CTMX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 14 analysts
  • Strong Buy 6 42.9%
  • Buy 7 50.0%
  • Hold 1 7.1%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

8 analysts · 2026-08-14
Median target $12.00 +240.9%
Mean target $12.25 +248.0%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.01%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.09 $-0.08 -0.01%
March 31, 2026 $-0.10 $-0.12 0.02%
Dec. 31, 2025 $-0.22 $-0.10 -0.12%
Sept. 30, 2025 $-0.09 $-0.05 -0.04%
June 30, 2025 $-0.00 $-0.08 0.08%
March 31, 2025 $0.27 $0.13 0.14%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CTMX $725M -44.8% -22.8% -15.9%
RIGL $784M 2.2 64.1% 124.7% 155.1%
AURA $347M -3.1 -29.7% -1601.4% -68.2%
MNPR
FDMT $432M -3.1 230194.6% -164.4% -30.2%
ACHV -4.0
NGNE $319M -4.9 -33.6%
STTK $231M -5.2 -82.5% -4880.9% -70.0%
RGNX $733M -3.8 104.5% -113.8% -122.5%
BBOT $1.00B -2.9 -146.2%
IRWD $550M 22.5 -15.7% 8.1% -8.5%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for CTMX
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +1400.9% $76M $138M $101M $53M $37M $68M $27M $60M $72M $15M $8M $5M
R&D Expense 12-point trend, +142.8% $69M $83M $78M $112M $114M $113M $132M $104M $92M $55M $28M $28M
SG&A Expense 12-point trend, +356.2% $30M $30M $30M $43M $39M $36M $37M $34M $26M $20M $13M $7M
Operating Expenses 12-point trend, +182.9% $99M $113M $108M $154M $153M $149M $168M $137M $118M $75M $41M $35M
Operating Income 12-point trend, +24.9% $-22M $25M $-6M $-101M $-116M $-81M $-141M $-78M $-46M $-60M $-33M $-30M
Interest Expense 3-point trend, +246.8% · · · · · · · · · $2M $2M $487.0K
Interest Income 12-point trend, +74271.4% $5M $7M $10M $2M $255.0K $2M $8M $8M $3M $736.0K $1M $7.0K
Other Non-op 12-point trend, +150.9% $28.0K $-38.0K $-30.0K $340.0K $-83.0K $-27.0K $-135.0K $-68.0K $-27.0K $-69.0K $-2M $-55.0K
Pretax Income 12-point trend, +43.5% $-17M $32M $3M $-99M $-116M $-79M $-133M $-70M $-44M $-59M $-35M $-30M
Income Tax 12-point trend, +2280.0% $238.0K $224.0K $4M $0 $0 $-14M $-427.0K $14M $-513.0K $-19.0K $10.0K $10.0K
Net Income 12-point trend, +42.7% $-17M $32M $-569.0K $-99M $-116M $-65M $-133M $-85M $-43M $-59M $-35M $-30M
Shares (Basic) 7-point trend, +204.3% 137,935,873 84,439,303 73,808,237 65,739,844 64,146,848 46,145,563 45,335,927 · · · · ·
Shares (Diluted) 7-point trend, +204.3% 137,935,873 84,745,116 73,808,237 65,739,844 64,146,848 46,145,563 45,335,927 · · · · ·
EBITDA 8-point trend, +32.6% $-22M $25M $-6M $-101M · $-49M $-111M $-78M · · $-33M ·
Balance Sheet 27
Annual Balance Sheet data for CTMX
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, -80.3% $13M $38M $17M $194M $206M $192M $188M $248M $178M $105M $60M $64M
Short-term Investments 4-point trend, +196562000.00 · · · · · · · · $197M $77M $127M $0
Receivables 12-point trend, +7.4% $2M $3M $3M $36M $790.0K $798.0K $13.0K $97.0K $10M $2M $372.0K $2M
Prepaid Expense 12-point trend, +907.5% $5M $4M $5M $7M $4M $7M $7M $9M $4M $4M $2M $482.0K
Current Assets 12-point trend, +115.3% $144M $107M $183M $237M $310M $324M $303M $445M $389M $188M $190M $67M
PP&E (Net) 12-point trend, -56.8% $1M $2M $4M $5M $6M $7M $7M $7M $4M $4M $3M $3M
PP&E (Gross) 12-point trend, +263.8% $18M $19M $19M $19M $20M $18M $16M $14M $9M $8M $6M $5M
Accum. Depreciation 12-point trend, +749.4% $17M $16M $15M $14M $14M $11M $9M $7M $5M $4M $3M $2M
Goodwill Flat — no change across 12 periods $949.0K $949.0K $949.0K $949.0K $949.0K $949.0K $949.0K $949.0K $949.0K $949.0K $949.0K $949.0K
Intangibles Flat — no change across 2 periods · · · · · · · · · · $2M $2M
Other Non-current Assets 12-point trend, -93.7% $31.0K $66.0K $83.0K $27.0K $901.0K $2M $2M $1M $1M $3M $364.0K $492.0K
Total Assets 12-point trend, +107.4% $152M $121M $202M $261M $339M $359M $341M $457M $398M $199M $197M $73M
Accounts Payable 12-point trend, -32.2% $1M $1M $1M $3M $3M $3M $4M $5M $4M $7M $5M $2M
Accrued Liabilities 12-point trend, +737.6% $14M $12M $18M $24M $34M $23M $30M $27M $16M $9M $5M $2M
Current Liabilities 12-point trend, +317.6% $47M $86M $156M $153M $78M $68M $86M $98M $61M $36M $16M $11M
Capital Leases 7-point trend, -100.0% $0 $4M $9M $14M $18M $22M $25M · · · · ·
Deferred Tax 3-point trend, +2.8% · · · · · · · · · $513.0K $507.0K $499.0K
Other Non-current Liabilities 10-point trend, +1648.2% $4M $4M $4M $0 · · $850.0K $3M $2M $566.0K $198.0K $249.0K
Total Liabilities 12-point trend, -29.8% $53M $121M $249M $347M $340M $366M $290M $326M $328M $121M $71M $75M
Long-term Debt · · · · · · · · · · · $3M
Common Stock 12-point trend, +100.0% $2.0K $1.0K $1.0K $1.0K $1.0K $1.0K $1.0K $1.0K $1.0K $1.0K $1.0K $1.0K
Paid-in Capital 11-point trend, +232.7% $811M $691M $676M $637M $623M $500M $468M $446M $289M $255M $244M ·
Retained Earnings 12-point trend, -811.1% $-712M $-692M $-723M $-723M $-624M $-508M $-443M $-315M $-219M $-176M $-117M $-78M
AOCI 11-point trend, +246.1% $111.0K $27.0K $95.0K $10.0K $-242.0K $-47.0K $57.0K $-93.0K $-94.0K $-27.0K $-76.0K ·
Stockholders' Equity 12-point trend, +226.1% $99M $-456.0K $-47M $-86M $-459.0K $-8M $25M $136M $70M $78M $126M $-79M
Liabilities + Equity 12-point trend, +107.4% $152M $121M $202M $261M $339M $359M $341M $457M $398M $199M $197M $73M
Shares Outstanding 12-point trend, +16978.1% 170,186,365 80,099,889 67,310,838 66,228,046 65,392,758 48,251,819 45,523,088 45,083,209 38,478,560 36,490,169 36,033,209 996,520
Cash Flow 14
Annual Cash Flow data for CTMX
Metric Trend 202520242023202220212020201920182017201620152014
D&A 5-point trend, +140.6% · · · · · · · $2M $2M $2M $1M $783.0K
Stock-based Comp 12-point trend, +1039.6% $6M $8M $9M $13M $13M $15M $19M $17M $11M $10M $4M $553.0K
Deferred Tax 10-point trend, -100.0% $0 $0 $0 $0 $0 · $-37.0K · $-514.0K $-20.0K $8.0K $9.0K
Amort. of Intangibles Flat — no change across 9 periods $146.0K $146.0K $146.0K $146.0K $146.0K $146.0K $146.0K $146.0K $146.0K · · ·
Operating Cash Flow 12-point trend, -337.7% $-76M $-86M $-56M $-111M $-119M $5M $-140M $-76M $170M $-2M $-27M $32M
CapEx 12-point trend, -86.8% $220.0K $310.0K $840.0K $2M $2M $2M $3M $4M $2M $2M $2M $2M
Investing Cash Flow 10-point trend, -230.3% $-60M $100M $-151M $98M $22M $-19M $80M $6M $-121M $46M · ·
Stock Issued 8-point trend, +449.4% $110M $7M · $0 $108M $11M $0 $135M $20M · · ·
Net Stock Activity 5-point trend, -18.5% $110M $7M · $0 · $11M · $135M · · · ·
Financing Cash Flow 10-point trend, +10989.0% $110M $8M $30M $648.0K $110M $17M $2M $140M $24M $996.0K · ·
Net Change in Cash 4-point trend, +30.9% · · · · · · · · $73M $45M $-5M $56M
Taxes Paid 3-point trend, -100.0% · · · · $0 $0 $13M · · · · ·
Free Cash Flow 8-point trend, -161.3% $-76M $-87M $-57M $-113M · $3M $-144M $-79M · · $-29M ·
Levered FCF · · · · · · · · · · $-31M ·
Profitability 7
Annual Profitability data for CTMX
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 8-point trend, +93.2% -29.3% 18.1% -6.4% -190.6% · -48.4% -192.9% -130.9% · · -430.5% ·
Net Margin 8-point trend, +95.0% -22.8% 23.1% -0.56% -186.8% · -32.8% -177.8% -142.2% · · -458.7% ·
Pretax Margin 8-point trend, +95.1% -22.5% 23.2% 3.3% -186.8% · -46.6% -178.6% -118.2% · · -458.6% ·
EBITDA Margin 8-point trend, +93.2% -29.3% 18.1% -6.4% -190.6% · -48.4% -192.9% -130.9% · · -430.5% ·
ROA 8-point trend, +51.2% -12.8% 19.8% -0.25% -33.1% · -9.4% -25.6% -19.8% · · -26.2% ·
ROE 8-point trend, +89.3% -15.9% -266.6% 1.1% 119.4% · -67.2% -153.5% -58.6% · · -148.9% ·
ROIC 8-point trend, +13.1% -22.9% -5443.1% -2.3% 118.2% · -68.6% -216.1% -71.6% · · -26.3% ·
Liquidity & Solvency 3
Annual Liquidity & Solvency data for CTMX
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 8-point trend, -74.4% 3.1 1.3 1.2 1.6 · 3.2 3.5 4.5 · · 12.1 ·
Quick Ratio 8-point trend, -97.4% 0.3 0.5 0.1 1.5 · 1.9 2.2 2.5 · · 11.9 ·
Interest Coverage · · · · · · · · · · -19.2 ·
Efficiency 2
Annual Efficiency data for CTMX
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 8-point trend, +880.9% 0.6 0.9 0.4 0.2 · 0.3 0.1 0.1 · · 0.1 ·
Receivables Turnover 8-point trend, +405.8% 29.8 42.3 5.1 2.9 · 247.5 1045.3 11.6 · · 5.9 ·
Per Share 4
Annual Per Share data for CTMX
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 8-point trend, -83.4% $0.58 $-0.01 $-0.70 $-1.29 · $1.03 $1.12 $2.90 · · $3.50 ·
Revenue / Share 4-point trend, -31.7% $0.55 $1.63 $1.37 $0.81 · · · · · · · ·
Cash Flow / Share 4-point trend, +67.5% $-0.55 $-1.02 $-0.76 $-1.69 · · · · · · · ·
Cash / Share 8-point trend, -95.5% $0.07 $0.48 $0.26 $2.92 · $3.98 $4.14 $5.49 · · $1.66 ·
Growth Rates 3
Annual Growth Rates data for CTMX
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +1.4% -44.8% 36.4% 90.4% 42.5% -45.5% · · · · · · ·
Revenue CAGR 3Y 3-point trend, -8.5% 12.8% 54.7% 13.9% · · · · · · · · ·
Revenue CAGR 5Y 2.2% · · · · · · · · · · ·
Valuation (TTM) 8
Annual Valuation (TTM) data for CTMX
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 11-point trend, +888.1% $76M $138M $101M $53M $37M $68M $27M $60M $72M $15M $8M ·
Net Income TTM 11-point trend, +50.9% $-17M $32M $-569.0K $-99M $-116M $-65M $-133M $-85M $-43M $-59M $-35M ·
Market Cap 8-point trend, -3.6% $725M $83M $104M $106M · $316M $378M $681M · · $752M ·
P/S 8-point trend, -90.2% 9.5 0.6 1.0 2.0 · 4.6 14.1 11.4 · · 97.5 ·
P/B 8-point trend, +22.8% 7.3 -180.9 -2.2 -1.2 · 6.3 7.4 5.2 · · 6.0 ·
P / Tangible Book 7.4 · · · · · · · · · · ·
P / Cash Flow 8-point trend, +65.0% -9.6 -1.0 -1.9 -1.0 · 60.1 -2.7 -9.0 · · -27.4 ·
P / FCF 8-point trend, +63.1% -9.6 -1.0 -1.8 -0.9 · 107.1 -2.6 -8.6 · · -25.9 ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $76M$138M$101M$53M$37M
Operating Margin % -29.3%18.1%-6.4%-190.6%
Net Income $-17M$32M$-569.0K$-99M$-116M
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 3.11.31.21.6
Quick Ratio 0.30.50.11.5
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-76M$-87M$-57M$-113M

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 188 filers · $639.8M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
56 (-19 vs prior Q) 45 (+26 vs prior Q) 57 (-1 vs prior Q) 41 (+12 vs prior Q) +8.4M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
FMR LLC $99,932,816 26,648,751 15.62% Shares
Kynam Capital Management, LP $81,386,599 21,703,093 12.72% Shares
STATE STREET CORP $44,052,135 11,747,236 6.89% Shares
PERCEPTIVE ADVISORS LLC $39,146,944 10,439,185 6.12% Shares
BANK OF AMERICA CORP /DE/ $33,995,602 9,065,494 5.31% Shares
VANGUARD CAPITAL MANAGEMENT LLC $31,970,464 8,525,457 5.00% Shares
Point72 Asset Management, L.P. $29,291,374 7,811,033 4.58% Shares
Venrock Adviser, LLC $18,682,965 4,982,124 2.92% Shares
BAKER BROS. ADVISORS LP $18,659,348 4,975,826 2.92% Shares
Elmind Capital, LP $17,062,500 4,550,000 2.67% Shares
Nextech Invest Ltd. $16,687,245 4,449,932 2.61% Shares
TWO SIGMA INVESTMENTS, LP $15,497,411 4,132,643 2.42% Shares
GEODE CAPITAL MANAGEMENT, LLC $15,057,333 4,014,472 2.35% Shares
Eversept Partners, LP $13,344,364 3,558,497 2.09% Shares
Siren, L.L.C. $12,966,416 3,457,711 2.03% Shares
ADAR1 Capital Management, LLC $12,619,193 3,365,118 1.97% Shares
WELLINGTON MANAGEMENT GROUP LLP $11,990,888 3,197,570 1.87% Shares
CITADEL ADVISORS LLC $11,663,138 3,110,170 1.82% Shares
Woodline Partners LP $7,650,788 2,040,210 1.20% Shares
Qube Research & Technologies Ltd $6,842,115 1,824,564 1.07% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $6,566,876 1,751,167 1.03% Shares
DIMENSIONAL FUND ADVISORS LP $6,503,445 1,734,252 1.02% Shares
MILLENNIUM MANAGEMENT LLC $6,321,862 1,685,830 0.99% Shares
TUDOR INVESTMENT CORP ET AL $5,177,576 1,380,687 0.81% Shares
GOLDMAN SACHS GROUP INC $5,175,859 1,380,229 0.81% Shares
VANGUARD FIDUCIARY TRUST CO $4,752,863 1,267,430 0.74% Shares
SPHERA FUNDS MANAGEMENT LTD. $3,296,250 879,000 0.52% Shares
Ally Bridge Group (NY) LLC $2,906,250 775,000 0.45% Shares
DV EQUITIES, LLC $2,677,500 714,000 0.42% Shares
GILDER GAGNON HOWE & CO LLC $2,641,586 704,423 0.41% Shares
Caption Management, LLC $2,625,000 700,000 0.41% Call option
FIRST TRUST ADVISORS LP $2,248,860 599,696 0.35% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $2,062,031 549,875 0.32% Shares
Ensign Peak Advisors, Inc $1,893,956 505,055 0.30% Shares
SCHULHOFF & CO INC $1,790,812 477,550 0.28% Shares
Exome Asset Management LLC $1,725,251 460,067 0.27% Shares
DAFNA Capital Management LLC $1,644,026 438,407 0.26% Shares
Caption Management, LLC $1,575,000 420,000 0.25% Put option
TWO SIGMA ADVISERS, LP $1,429,332 335,524 0.22% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,395,000 372,000 0.22% Call option
Seven Fleet Capital Management LP $1,392,743 371,398 0.22% Shares
Assenagon Asset Management S.A. $1,365,649 364,173 0.21% Shares
Jump Financial, LLC $1,302,750 347,400 0.20% Shares
Swiss National Bank $1,220,250 325,400 0.19% Shares
Caption Management, LLC $1,125,000 300,000 0.18% Shares
BlackRock, Inc. $1,118,576 298,287 0.17% Shares
CITIGROUP INC $1,040,974 277,593 0.16% Shares
LMR Partners LLP $1,024,549 273,213 0.16% Shares
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $890,180 189,400 0.14% Shares
MARSHALL WACE, LLP $855,715 228,190 0.13% Shares
RHUMBLINE ADVISERS $834,420 222,514 0.13% Shares
Rafferty Asset Management, LLC $830,164 221,377 0.13% Shares
Stonepine Capital Management, LLC $768,750 205,000 0.12% Shares
Focus Partners Wealth $742,043 197,878 0.12% Shares
Bank of New York Mellon Corp $708,754 189,001 0.11% Shares
Verdad Advisers, LP $661,526 176,407 0.10% Shares
LPL Financial LLC $643,999 171,733 0.10% Shares
HighVista Strategies LLC $636,866 169,831 0.10% Shares
WELLS FARGO & COMPANY/MN $586,268 156,338 0.09% Shares
AWM Investment Company, Inc. $562,500 150,000 0.09% Shares
CANADA PENSION PLAN INVESTMENT BOARD $530,625 141,500 0.08% Shares
CITADEL ADVISORS LLC $491,250 131,000 0.08% Call option
ALLIANCEBERNSTEIN L.P. $490,257 104,310 0.08% Shares
Walleye Capital LLC $474,473 126,526 0.07% Shares
NLB Skladi, upravljanje premozenja, d.o.o. $468,750 125,000 0.07% Shares
VANGUARD ASSET MANAGEMENT, Ltd $460,849 122,893 0.07% Shares
Velan Capital Investment Management LP $450,000 120,000 0.07% Shares
Squarepoint Ops LLC $420,570 112,152 0.07% Shares
PROFUND ADVISORS LLC $417,668 111,378 0.07% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $415,381 88,379 0.06% Shares
Virtus Investment Advisers, LLC $407,636 108,703 0.06% Shares
ALPS ADVISORS INC $401,625 107,100 0.06% Shares
MetLife Investment Management, LLC $392,381 104,635 0.06% Shares
Aspire Growth Partners LLC $383,452 102,254 0.06% Shares
Robertson Stephens Wealth Management, LLC $360,000 96,000 0.06% Shares
ALGERT GLOBAL LLC $340,875 90,900 0.05% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $340,024 90,673 0.05% Shares
CITADEL ADVISORS LLC $332,250 88,600 0.05% Put option
BARCLAYS PLC $321,191 85,651 0.05% Shares
Miller Financial Services LLC $318,750 85,000 0.05% Shares
Engineers Gate Manager LP $311,738 83,130 0.05% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $307,125 81,900 0.05% Put option
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $306,068 81,618 0.05% Shares
Zurcher Kantonalbank (Zurich Cantonalbank) $299,310 79,816 0.05% Shares
Vanguard Global Advisers, LLC $268,564 71,617 0.04% Shares
Invesco Ltd. $266,194 70,985 0.04% Shares
Skopos Labs, Inc. $260,747 55,478 0.04% Shares
China Universal Asset Management Co., Ltd. $242,426 64,647 0.04% Shares
VANGUARD GROUP INC $232,472 54,571 0.04% Shares
JANUS HENDERSON GROUP PLC $219,724 46,700 0.03% Shares
RAYMOND JAMES FINANCIAL INC $213,000 56,800 0.03% Shares
State of Wyoming $206,201 54,987 0.03% Shares
AMERICAN CENTURY COMPANIES INC $205,871 54,899 0.03% Shares
Private Advisor Group, LLC $204,383 54,502 0.03% Shares
Police & Firemen's Retirement System of New Jersey $196,871 52,499 0.03% Shares
State of New Jersey Common Pension Fund D $196,590 52,424 0.03% Shares
Toroso Investments, LLC $194,950 45,763 0.03% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $189,484 50,529 0.03% Shares
TUDOR INVESTMENT CORP ET AL $188,625 50,300 0.03% Call option
Congress Park Capital LLC $184,392 49,171 0.03% Shares

Company insiders 30 insiders · 12 officers · 15 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Sean A. Mccarthy CEO March 16, 2023 S 388,821 0 0 $0
Christopher Ogden Chief Financial Officer June 15, 2026 S 295,324 0 1 $-4,953
Jeffrey B Landau Chief Financial Officer March 16, 2023 S 69,248 0 0 $0
Carlos Campoy Chief Financial Officer March 16, 2023 S 38,224 0 0 $0
Debanjan Ray Chief Financial Officer Aug. 1, 2018 M 5,928 0 0 $0
Ii Robert C. Goeltz Chief Financial Officer May 12, 2017 M 32,756 0 0 $0
Marcia Belvin SVP, Chief Scientific Officer March 22, 2023 A 140,820 0 0 $0
Amy C. Peterson EVP, Chief Development Officer March 16, 2023 S 58,433 0 0 $0
Lloyd A Rowland General Counsel March 16, 2023 S 71,095 0 0 $0
Rachel Humphrey Chief Medical Officer March 2, 2018 M 30,234 0 0 $0
William Michael Kavanaugh CSO, Head Res.&Non-Clin. Dev. Jan. 24, 2018 A 19,047 0 0 $0
Cynthia J Ladd Senior VP and General Counsel Jan. 25, 2017 A 3,000 0 0 $0
Charles S. Fuchs Director July 24, 2026 A 0 0 $0
Zhen Su Director June 17, 2026 A 0 0 $0
Alan Ashworth Director June 17, 2026 A 0 0 $0
Mani Mohindru Director June 17, 2026 A 0 0 $0
Matthew P. Young Director June 17, 2026 A 0 0 $0
Halley E Gilbert Director June 17, 2026 A 0 0 $0
James R Meyers Director June 17, 2026 A 0 0 $0
Elaine V Jones Director June 17, 2026 A 5,142 0 0 $0
Hoyoung Huh Director June 13, 2018 A 0 0 $0
John A Scarlett Director June 13, 2018 A 0 0 $0
Frederick W Gluck Director June 13, 2018 A 271,643 0 0 $0
Marion Mccourt Director June 20, 2017 A 0 0 $0
Neil Exter Director June 20, 2017 A 0 0 0 $0
Timothy M Shannon Director Nov. 29, 2016 S 3,244,381 0 0 $0
Robert I Tepper 10% owner Oct. 4, 2017 S 29,516 0 0 $0
Kevin P Starr 10% owner April 12, 2017 S 31,419 0 0 $0
Hadley Harbor Master Investors (Cayman) L.P. 10% owner Oct. 14, 2015 C 749,055 0 0 $0
Alejandra Carvajal Aug. 3, 2026 A 100,000 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 37 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
FMED · Fidelity Covington Trust 0.98% 112,069 NS May 31, 2026 N-PORT
BBC · ETFis Series Trust I 0.74% 65,872 NS April 30, 2026 N-PORT
IDNA · iShares Trust 0.64% 375,908 SH Aug. 8, 2026 Daily
QQQS · Invesco Exchange-Traded Fund Trust … 0.47% 31,061 SH Aug. 8, 2026 Daily
CANC · Tema ETF Trust 0.47% 228,987 NS May 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.21% 258,130 NS April 30, 2026 N-PORT
BFOR · ALPS ETF Trust 0.18% 105,982 NS May 31, 2026 N-PORT
IWC · iShares Trust 0.14% 602,006 SH Aug. 8, 2026 Daily
FFSM · FIDELITY COVINGTON TRUST 0.09% 290,427 NS April 30, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.05% 11,848 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.04% 1,218,047 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.03% 6,265 NS May 31, 2026 N-PORT
IWO · iShares Trust 0.02% 890,900 SH Aug. 8, 2026 Daily
ISCV · iShares Trust 0.02% 41,747 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.02% 1,024,499 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.02% 70,221 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.02% 104,846 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.02% 4,514,184 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.02% 751,702 SH Aug. 8, 2026 Daily
TECB · iShares Trust 0.01% 17,020 SH Aug. 8, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.01% 74,256 NS April 30, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.01% 2,095,997 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 484,160 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.01% 82,872 SH Aug. 8, 2026 Daily
ISCB · iShares Trust 0.01% 8,428 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.01% 297,321 NS April 30, 2026 N-PORT
WSML · iShares Trust 0.00% 5,815 SH Aug. 8, 2026 Daily
DCOR · Dimensional ETF Trust 0.00% 12,796 NS April 30, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.00% 1,429 NS April 30, 2026 N-PORT
IWV · iShares Trust 0.00% 59,165 SH Aug. 8, 2026 Daily
DFAU · Dimensional ETF Trust 0.00% 24,102 NS April 30, 2026 N-PORT
ITOT · iShares Trust 0.00% 224,306 SH Aug. 8, 2026 Daily
DFAC · Dimensional ETF Trust 0.00% 71,243 NS April 30, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 14,903 NS April 30, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 6,230,387 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 14,861 SH Aug. 8, 2026 Daily
DFUV · Dimensional ETF Trust 0.00% 282 NS April 30, 2026 N-PORT