Laura Brege
CIK 1365619 · View on SEC EDGAR ↗
Insider
First SEC filing: March 25, 2021 · Latest: June 12, 2026
On this page
Insider at
Insider transactions
0 buys (P)
0 sells (S)
Net:
$0
+ 84 non-open-market transactions below
last 12 months, based on the transactions shown below
Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted
84 other filings hidden
| Date | Ticker | Code | Shares | Price | Value | Owned after | Δ own | A/D | vs now |
|---|---|---|---|---|---|---|---|---|---|
| Aug. 16, 2024 | PCRX | P | 1,000 | $12.81 | $12,810 | 17,552 Direct | +6.04% | Acquired | 87.3% (price as of 2026-08-21) |
| June 12, 2023 | ACAD | S 10b5-1 | 4,500 | $24.87 | $111,915 | 13,502 Direct | -25.00% | Disposed | 16.8% (price as of 2026-08-21) |
| June 5, 2023 | PCRX | S 10b5-1 | 600 | $38.74 | $23,244 | 9,547 Direct | -5.91% | Disposed | -38.1% (price as of 2026-08-21) |
| April 3, 2023 | PCRX | S 10b5-1 | 7,000 | $40.72 | $285,040 | 10,147 Direct | -40.82% | Disposed | -41.1% (price as of 2026-08-21) |
| Jan. 12, 2023 | ACAD | S 10b5-1 | 12,500 | $18.25 | $228,125 | 0 Direct | -100.00% | Disposed | 59.2% (price as of 2026-08-21) |
| Nov. 16, 2020 | PCRX | S | 12,000 | $65.95 | $791,400 | 7,921 Direct | -60.24% | Disposed | -63.6% (price as of 2026-08-21) |
| June 5, 2020 | PCRX | S | 2,100 | $48.70 | $102,270 | 6,661 Direct | -23.97% | Disposed | -50.7% (price as of 2026-08-21) |
| Jan. 7, 2020 | ACAD | S 10b5-1 | 10,000 | $42.19 | $421,900 | 0 Direct | -100.00% | Disposed | -31.1% (price as of 2026-08-21) |
| Sept. 10, 2019 | MIRM | P | 10,000 | $11.22 | $112,200 | 10,000 Direct | — | Acquired | 768.1% (price as of 2026-08-21) |
| Jan. 9, 2019 | ACAD | S 10b5-1 | 10,000 | $20.00 | $200,000 | 0 Direct | -100.00% | Disposed | 45.3% (price as of 2026-08-21) |
| Jan. 2, 2018 | ACAD | S 10b5-1 | 25,000 | $30.06 | $751,500 | 0 Direct | -100.00% | Disposed | -3.3% (price as of 2026-08-21) |
| June 6, 2016 | PCRX | S 10b5-1 | 1,000 | $46.95 | $46,950 | 1,000 Direct | -50.00% | Disposed | -48.9% (price as of 2026-08-21) |
| Feb. 11, 2015 | ACAD | S 10b5-1 | 10,000 | $33.63 | $336,300 | 0 Direct | -100.00% | Disposed | -13.6% (price as of 2026-08-21) |
| Sept. 15, 2014 | ACAD | S 10b5-1 | 10,000 | $28.07 | $280,700 | 0 Direct | -100.00% | Disposed | 3.5% (price as of 2026-08-21) |
| May 9, 2014 | PCRX | S 10b5-1 | 2,500 | $74.67 | $186,675 | 0 Direct | -100.00% | Disposed | -67.9% (price as of 2026-08-21) |
| May 9, 2014 | PCRX | S 10b5-1 | 7,500 | $73.57 | $551,775 | 2,500 Direct | -75.00% | Disposed | -67.4% (price as of 2026-08-21) |
Showing latest 100 of 132 transactions
P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding
Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.
Derivative holdings (Form 4 Table II)
Options, RSUs and convertible securities reported on Form 4 Table II.
| Date | Ticker | Security | Underlying | Exercise price | Expiration | Shares | A/D |
|---|---|---|---|---|---|---|---|
| June 15, 2026 | MIRM | Deferred Stock Units | Common Stock (1,980) | — | — | 1,980 | Acquired |
| June 15, 2026 | MIRM | Stock Option (right to buy) | Common Stock (3,772) | $101.00 | June 14, 2036 | 3,772 | Acquired |
| June 10, 2026 | PCRX | Stock Option (Right to Buy) | Common Stock (10,891) | $23.42 | June 10, 2036 | 10,891 | Acquired |
| June 5, 2026 | EWTX | Stock Option (Right to Buy) | Common Stock (16,377) | $35.59 | June 5, 2036 | 16,377 | Acquired |
| May 29, 2026 | ACAD | Restricted Stock Units | Common Stock (9,311) | — | — | 9,311 | Acquired |
| May 29, 2026 | ACAD | Director Stock Options (Right to Buy) | Common Stock (16,004) | $21.66 | May 28, 2036 | 16,004 | Acquired |
| May 29, 2026 | ACAD | Restricted Stock Units | Common Stock (8,107) | — | — | 8,107 | Disposed |
| June 11, 2025 | PCRX | Stock Option (Right to Buy) | Common Stock (11,279) | $24.34 | June 11, 2035 | 11,279 | Acquired |
| June 12, 2024 | PCRX | Stock Option (Right to Buy) | Common Stock (12,179) | $28.68 | June 12, 2034 | 12,179 | Acquired |
| June 5, 2024 | MIRM | Stock Option (right to buy) | Common Stock (8,779) | $26.30 | June 4, 2034 | 8,779 | Acquired |
| June 5, 2024 | MIRM | Restricted Stock Units | Common Stock (5,703) | — | — | 5,703 | Acquired |
| May 29, 2024 | ACAD | Restricted Stock Units | Common Stock (6,652) | — | — | 6,652 | Disposed |
| May 29, 2024 | ACAD | Director Stock Options (Right to Buy) | Common Stock (15,959) | $14.62 | May 28, 2034 | 15,959 | Acquired |
| May 29, 2024 | ACAD | Restricted Stock Units | Common Stock (9,387) | — | — | 9,387 | Acquired |
| June 14, 2023 | PCRX | Stock Option (Right to Buy) | Common Stock (12,925) | $38.74 | June 14, 2033 | 12,925 | Acquired |
| June 12, 2023 | MIRM | Stock Option (right to buy) | Common Stock (17,000) | $28.97 | June 11, 2033 | 17,000 | Acquired |
| June 1, 2023 | ACAD | Restricted Stock Units | Common Stock (6,652) | — | — | 6,652 | Acquired |
| June 1, 2023 | ACAD | Director Stock Options (Right to Buy) | Common Stock (11,045) | $23.90 | May 31, 2033 | 11,045 | Acquired |
| June 1, 2023 | ACAD | Restricted Stock Units | Common Stock (8,552) | — | — | 8,552 | Disposed |
| April 3, 2023 | PCRX | Stock Option (Right to Buy) | Common Stock (7,000) | $29.90 | June 12, 2023 | 7,000 | Disposed |
| Jan. 12, 2023 | ACAD | Stock Option (Right to Buy) | Common Stock (12,500) | $17.01 | June 6, 2023 | 12,500 | Disposed |
| June 8, 2022 | PCRX | Stock Option (Right to Buy) | Common Stock (8,225) | $59.39 | June 8, 2032 | 8,225 | Acquired |
| June 7, 2022 | ACAD | Restricted Stock Units | Common Stock (6,391) | — | — | 6,391 | Disposed |
| June 7, 2022 | ACAD | Restricted Stock Units | Common Stock (8,552) | — | — | 8,552 | Acquired |
| June 7, 2022 | ACAD | Director Stock Options (Right to Buy) | Common Stock (14,368) | $18.27 | June 6, 2032 | 14,368 | Acquired |
| June 2, 2022 | MIRM | Stock Option (right to buy) | Common Stock (17,000) | $23.51 | June 1, 2032 | 17,000 | Acquired |
| June 22, 2021 | ACAD | Restricted Stock Units | Common Stock (3,059) | — | — | 3,059 | Disposed |
| June 22, 2021 | ACAD | Director Stock Options (Right to Buy) | Common Stock (11,637) | $24.88 | June 21, 2031 | 11,637 | Acquired |
| June 22, 2021 | ACAD | Restricted Stock Units | Common Stock (6,391) | — | — | 6,391 | Acquired |
| June 9, 2021 | PCRX | Stock Option (Right to Buy) | Common Stock (7,626) | $60.96 | June 9, 2031 | 7,626 | Acquired |
| June 4, 2021 | MIRM | Stock Option (right to buy) | Common Stock (17,000) | $16.88 | June 3, 2031 | 17,000 | Acquired |
| Nov. 16, 2020 | PCRX | Stock Option (Right to Buy) | Common Stock (12,000) | $13.98 | June 2, 2021 | 12,000 | Disposed |
| June 23, 2020 | ACAD | Restricted Stock Units | Common Stock (3,059) | — | — | 3,059 | Acquired |
| June 23, 2020 | ACAD | Director Stock Options (Right to Buy) | Common Stock (5,579) | $52.73 | June 22, 2030 | 5,579 | Acquired |
| June 11, 2020 | MIRM | Stock Option (right to buy) | Common Stock (14,167) | $16.71 | June 10, 2030 | 14,167 | Acquired |
| June 9, 2020 | PCRX | Stock Option (Right to Buy) | Common Stock (8,027) | $47.65 | June 9, 2030 | 8,027 | Acquired |
| Jan. 7, 2020 | ACAD | Stock Option (Right to Buy) | Common Stock (10,000) | $1.75 | June 9, 2021 | 10,000 | Disposed |
| July 17, 2019 | MIRM | Stock Option (right to buy) | Common Stock (17,000) | $15.00 | July 16, 2029 | 17,000 | Acquired |
| June 26, 2019 | ACAD | Stock Option (Right to Buy) | Common Stock (15,000) | $25.24 | June 26, 2029 | 15,000 | Disposed |
| June 5, 2019 | PCRX | Stock Option (Right to Buy) | Common Stock (8,437) | $43.54 | June 5, 2029 | 8,437 | Acquired |
| Jan. 9, 2019 | ACAD | Stock Option (Right to Buy) | Common Stock (10,000) | $2.16 | June 11, 2019 | 10,000 | Disposed |
| June 13, 2018 | PCRX | Stock Option (Right to Buy) | Common Stock (4,693) | $38.35 | June 13, 2028 | 4,693 | Acquired |
| June 6, 2018 | ACAD | Stock option (right to buy) | Common Stock (15,000) | $17.52 | June 5, 2028 | 15,000 | Acquired |
| Jan. 2, 2018 | ACAD | Stock option (right to buy) | Common Stock (15,000) | $8.06 | April 30, 2018 | 15,000 | Disposed |
| Jan. 2, 2018 | ACAD | Stock option (right to buy) | Common Stock (10,000) | $8.49 | June 12, 2018 | 10,000 | Disposed |
| June 14, 2017 | PCRX | Stock Option (Right to Buy) | Common Stock (2,714) | $44.20 | June 14, 2027 | 2,714 | Acquired |
| June 13, 2017 | ACAD | Stock Option (right to buy) | Common Stock (15,000) | $27.25 | June 12, 2027 | 15,000 | Acquired |
| June 15, 2016 | PCRX | Stock Option (Right to Buy) | Common Stock (2,975) | $40.34 | June 15, 2026 | 2,975 | Acquired |
| June 10, 2016 | ACAD | Stock option (right to buy) | Common Stock (12,500) | $39.60 | June 9, 2026 | 12,500 | Acquired |
| June 15, 2015 | ACAD | Stock option (right to buy) | Common Stock (12,500) | $39.06 | June 14, 2025 | 12,500 | Acquired |
| June 3, 2015 | PCRX | Stock Option (Right to Buy) | Common Stock (4,000) | $79.43 | June 3, 2025 | 4,000 | Acquired |
| Feb. 11, 2015 | ACAD | Stock option (right to buy) | Common Stock (10,000) | $1.75 | June 9, 2021 | 10,000 | Disposed |
| Sept. 15, 2014 | ACAD | Stock option (right to buy) | Common Stock (10,000) | $1.75 | June 9, 2021 | 10,000 | Disposed |
| June 6, 2014 | ACAD | Stock option (right to buy) | Common Stock (12,500) | $21.99 | June 5, 2024 | 12,500 | Acquired |
| June 3, 2014 | PCRX | Stock Option (Right to Buy) | Common Stock (8,000) | $81.00 | June 3, 2024 | 8,000 | Acquired |
| May 9, 2014 | PCRX | Stock Option (Right to Buy) | Common Stock (3,000) | $13.98 | June 2, 2021 | 3,000 | Disposed |
| May 9, 2014 | PCRX | Stock Option (Right to Buy) | Common Stock (7,000) | $10.81 | June 4, 2022 | 7,000 | Disposed |
| April 4, 2014 | ACAD | Stock option (right to buy) | Common Stock (14,285) | $1.75 | June 9, 2021 | 14,285 | Disposed |
| Jan. 15, 2014 | ACAD | Stock option (right to buy) | Common stock (10,000) | $1.36 | June 7, 2022 | 10,000 | Disposed |
| Dec. 10, 2013 | ACAD | Stock option (right to buy) | Common stock (44,117) | $1.36 | June 7, 2022 | 44,117 | Disposed |
| Oct. 10, 2013 | ACAD | Stock option (right to buy) | Common stock (10,000) | $1.30 | June 10, 2020 | 10,000 | Disposed |
| Sept. 10, 2013 | ACAD | Stock option (right to buy) | Common stock (46,153) | $1.30 | June 10, 2020 | 46,153 | Disposed |
| June 12, 2013 | PCRX | Stock Option (Right to Buy) | Common Stock (7,000) | $29.20 | June 11, 2023 | 7,000 | Acquired |
| June 7, 2013 | ACAD | Stock option (right to buy) | Common stock (12,500) | $17.01 | June 6, 2023 | 12,500 | Acquired |
| July 6, 2012 | DCTH | Stock Option (right to buy) | Common Stock (54,586) | $2.00 | July 6, 2022 | 54,586 | Acquired |
| June 8, 2012 | ACAD | Stock option (right to buy) | Common stock (10,000) | $1.36 | June 7, 2022 | 10,000 | Acquired |
| June 8, 2012 | ACAD | Stock option (right to buy) | Common stock (44,117) | $1.36 | June 7, 2022 | 44,117 | Acquired |
| June 5, 2012 | PCRX | Common Stock | Common Stock (7,000) | $10.81 | June 4, 2022 | 7,000 | Acquired |
| June 10, 2011 | ACAD | Stock option (right to buy) | Common stock (10,000) | $1.75 | June 9, 2021 | 10,000 | Acquired |
| June 10, 2011 | ACAD | Stock option (right to buy) | Common stock (34,285) | $1.75 | June 9, 2021 | 34,285 | Acquired |
| June 2, 2011 | PCRX | Stock option (right to buy) | Common Stock (15,000) | $13.98 | June 2, 2021 | 15,000 | Acquired |
| June 11, 2010 | ACAD | Stock option (right to bou) | Common Stock (46,153) | $1.30 | June 10, 2020 | 46,153 | Acquired |
| June 11, 2010 | ACAD | Stock option (right to buy) | Common stock (10,000) | $1.30 | June 10, 2020 | 10,000 | Acquired |
| June 12, 2009 | ACAD | Stock Option (right to buy) | Common Stock (10,000) | $2.16 | June 11, 2019 | 10,000 | Acquired |
| June 13, 2008 | ACAD | Stock Option (right to buy) | Common Stock (10,000) | $8.49 | June 12, 2018 | 10,000 | Acquired |
| May 1, 2008 | ACAD | Option (right to buy) | Common Stock (15,000) | $8.06 | April 30, 2018 | 15,000 | Acquired |
Exercise/conversion price is blank when not applicable (e.g. RSUs).
Initial ownership (Form 3) 3 holdings
Securities held when first becoming an insider, per SEC Form 3.