MIRM Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03

Price $82.93

Market Cap (MRQ) $5.37B

P/E (TTM) -5.7

EPS (TTM) $-14.54

Revenue (TTM) $618M

ROE (TTM) -703.0%

52W Range $63–$130

MIRM Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04

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About Mirum Pharmaceuticals, Inc. - common stock Company overview from Wikipedia

05 · wikidata

Wikidata ↗

sectorHealthcare industryBiotechnology employees433 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06

Revenue$521M

2020-12-31 → 2025-12-31

EPS$-0.47

2021-12-31 → 2025-12-31

Free Cash Flow$55M

2019-12-31 → 2025-12-31

Net margin-139.2%

2021-12-31 → 2025-12-31

Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric	MIRM	5Y avg	Peer Median	Verdict
P/E (TTM)	-5.75Y avg ≈-41.7	≈-41.7	·	·
P/S (TTM)	8.75Y avg ≈11.2	≈11.2	15.4	Undervalued
P/B (MRQ)	-515.35Y avg ≈7.3	≈7.3	·	·
Price / FCF (TTM)	-23.55Y avg ≈52.0	≈52.0	·	·
Price / Cash Flow (TTM)	-23.65Y avg ≈47.6	≈47.6	·	·
Price / Tangible Book (MRQ)	-20.85Y avg ≈29.9	≈29.9	·	·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric	MIRM	5Y avg	Peer Median	Verdict
Operating Margin (TTM)	-134.9%5Y avg ≈-233.0%	≈-233.0%	-38.2%	Top tier
EBITDA Margin (TTM)	-130.7%5Y avg ≈-228.1%	≈-228.1%	-38.2%	Top tier
Pretax Margin (TTM)	-138.7%5Y avg ≈-148.0%	≈-148.0%	-37.2%	In line
Net Profit Margin (TTM)	-139.2%5Y avg ≈-146.6%	≈-146.6%	-42.9%	In line
ROA (TTM)	-97.2%5Y avg ≈-24.5%	≈-24.5%	-22.3%	Top tier
ROE (TTM)	-703.0%5Y avg ≈-58.4%	≈-58.4%	-35.2%	Top tier
ROIC	-7.7%5Y avg ≈-64.7%	≈-64.7%	-30.0%	Top tier

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric	5Y trend	MIRM	5Y avg	Peer Median	Verdict
Current Ratio (MRQ)		2.95Y avg ≈3.4	≈3.4	7.7	Low liquidity
Quick Ratio (MRQ)		2.65Y avg ≈3.2	≈3.2	3.5	Low liquidity

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric	5Y trend	MIRM	5Y avg	Peer Median	Verdict
Revenue YoY		54.7%5Y avg ≈145.0%	≈145.0%	·	·
Revenue CAGR 3Y		89.1%	·	·	·

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric	MIRM	5Y avg	Peer Median	Verdict
EPS (Diluted)	$-0.475Y avg ≈$-2.62	≈$-2.62	·	·
Revenue / Share	$10.395Y avg ≈$6.08	≈$6.08	·	·
Cash Flow / Share	$1.115Y avg ≈$-0.99	≈$-0.99	·	·
Cash / Share	$5.725Y avg ≈$3.65	≈$3.65	·	·

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric	MIRM	5Y avg	Peer Median	Verdict
Asset Turnover	0.75Y avg ≈0.4	≈0.4	0.2	Top tier
Receivables Turnover	5.25Y avg ≈6.2	≈6.2	8.4	Weak
Revenue / Employee	≈$1.2M	·	·	·

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14

Avg Surprise -63.1%

Next Report Nov 04, 2026

Period	Report	EPS Actual	EPS Est	Surprise
June 30, 2026	Aug 4, 2026	$-1.06	$-0.69	-52.6%
March 31, 2026		$-1.08	$-0.36	-199.7%
Dec. 31, 2025		$-0.10	$0.04	-330.9%
Sept. 30, 2025		$0.05	$-0.17	129.8%
June 30, 2025		$-0.12	$-0.33	64.0%
March 31, 2025		$-0.30	$-0.34	10.7%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15

Income Statement 14

Metric	2025	2024	2023	2022	2021	2020
Revenue	$521M	$337M	$186M	$77M	$19M	$0
SG&A Expense	$257M	$202M	$146M	$89M	$59M	$23M
Operating Expenses	$543M	$424M	$296M	$208M	$193M	$104M
Operating Income	$-22M	$-88M	$-109M	$-131M	$-173M	$-104M
Interest Income	$13M	$14M	$14M	$4M	$366.0K	$2M
Other Non-op	$2M	$1M	$-3M	$365.0K	$-582.0K	$-192.0K
Pretax Income	$-21M	$-87M	$-162M	$-142M	$-84M	$-103M
Income Tax	$2M	$1M	$991.0K	$-6M	$37.0K	$6.0K
Net Income	$-23M	$-88M	$-163M	$-136M	$-84M	$-103M
EPS (Basic)	$-0.47	$-1.85	$-4.00	$-4.01	$-2.77	·
EPS (Diluted)	$-0.47	$-1.85	$-4.00	$-4.02	$-2.77	·
Shares (Basic)	50,198,304	47,522,594	40,885,124	33,839,072	30,321,722	·
Shares (Diluted)	50,198,304	47,522,594	40,885,124	33,982,493	30,321,722	·
EBITDA	$2M	$-64M	$-98M	$-128M	$-173M	$-104M

Balance Sheet 23

Metric	2025	2024	2023	2022	2021	2020
Cash & Equivalents	$297M	$223M	$286M	$28M	$31M	$142M
Short-term Investments	$87M	$58M	$0	$124M	$125M	$90M
Receivables	$123M	$78M	$68M	$24M	$3M	$0
Inventory	$25M	$22M	$22M	$6M	$2M	$0
Prepaid Expense	$18M	$12M	$11M	$9M	$5M	$5M
Current Assets	$550M	$393M	$388M	$190M	$167M	$236M
PP&E (Net)	$2M	$1M	$706.0K	$914.0K	$981.0K	$1M
Accum. Depreciation	$1M	$700.0K	$2M	$1M	$700.0K	$300.0K
Intangibles	$261M	$250M	$253M	$59M	$19M	$0
Other Non-current Assets	$12M	$5M	$4M	$1M	$2M	$1M
Total Assets	$843M	$671M	$647M	$353M	$295M	$241M
Accounts Payable	$10M	$15M	$7M	$9M	$9M	$3M
Accrued Liabilities	$196M	$112M	$79M	$54M	$31M	$13M
Current Liabilities	$206M	$127M	$87M	$65M	$43M	$18M
Capital Leases	$8M	$8M	$617.0K	$1M	$2M	$3M
Other Non-current Liabilities	$5M	$3M	$4M	$5M	$17.0K	$29.0K
Total Liabilities	$528M	$445M	$398M	$211M	$174M	$69M
Common Stock	$5.0K	$5.0K	$5.0K	$4.0K	$3.0K	$3.0K
Retained Earnings	$-668M	$-644M	$-556M	$-393M	$-257M	$-173M
AOCI	$351.0K	$-373.0K	$2M	$-217.0K	$-35.0K	$83.0K
Stockholders' Equity	$315M	$226M	$249M	$142M	$120M	$172M
Liabilities + Equity	$843M	$671M	$647M	$353M	$295M	$241M
Shares Outstanding	51,896,391	48,338,096	46,723,143	36,956,345	30,582,596	29,776,544

Cash Flow 14

Metric	2025	2024	2023	2022	2021	2020
D&A	$24M	$24M	$11M	$3M	$595.0K	$305.0K
Stock-based Comp	$71M	$48M	$35M	$27M	$23M	$13M
Deferred Tax	$0	$0	$0	$-7M	$0	·
Amort. of Intangibles	$24M	$23M	$10M	$3M	$300.0K	·
Other Non-cash	$-16M	$26M	$47M	$-8M	$-72M	$1M
Operating Cash Flow	$56M	$10M	$-71M	$-120M	$-133M	$-89M
CapEx	$954.0K	$993.0K	$109.0K	$278.0K	$24.0K	$225.0K
Investing Cash Flow	$-24M	$-90M	$-107M	$8M	$49M	$38M
Stock Issued	$0	$0	$14M	$21M	$0	·
Net Stock Activity	$0	$0	$14M	$21M	·	·
Financing Cash Flow	$40M	$18M	$337M	$109M	$73M	$181M
Net Change in Cash	$75M	$-63M	$158M	$-3M	$-11M	$130M
Taxes Paid	$2M	$1M	$125.0K	$0	·	·
Free Cash Flow	$55M	$9M	$-71M	$-120M	$-133M	$-89M

Profitability 7

Metric	2025	2024	2023	2022	2021	2020
Operating Margin	-4.2%	-26.0%	-58.6%	-170.3%	-906.1%	·
Net Margin	-4.5%	-26.1%	-87.7%	-176.0%	-438.8%	·
Pretax Margin	-4.1%	-25.8%	-87.2%	-184.4%	-438.7%	·
EBITDA Margin	0.40%	-19.0%	-52.8%	-166.1%	-903.0%	·
ROA	-3.1%	-13.4%	-32.7%	-41.9%	-31.4%	-53.3%
ROE	-8.2%	-38.4%	-63.1%	-87.2%	-95.1%	-70.7%
ROIC	-7.7%	-39.3%	-44.2%	-88.2%	-144.3%	-60.6%

Liquidity & Solvency 2

Metric	Trend	2025	2024	2023	2022	2021	2020
Current Ratio		2.7	3.1	4.5	2.9	3.9	12.8
Quick Ratio		2.5	2.8	4.1	2.7	3.8	12.6

Efficiency 2

Metric	Trend	2025	2024	2023	2022	2021	2020
Asset Turnover		0.7	0.5	0.4	0.2	0.1	·
Receivables Turnover		5.2	4.6	4.1	5.7	11.7	·

Per Share 5

Metric	2025	2024	2023	2022	2021	2020
Book Value / Share	$6.06	$4.67	$5.32	$3.84	$3.93	$5.78
Revenue / Share	$10.39	$7.09	$4.56	$2.27	·	·
Cash Flow / Share	$1.11	$0.22	$-1.74	$-3.54	·	·
Cash / Share	$5.72	$4.60	$6.13	$0.76	$1.02	$4.77
EPS (TTM)	$-0.47	$-1.85	$-4.00	$-4.02	$-2.77	·

Growth Rates 2

Metric	Trend	2025	2024	2023	2022	2021	2020
Revenue YoY		54.7%	80.8%	141.9%	302.7%	·	·
Revenue CAGR 3Y		89.1%	160.1%	·	·	·	·

Valuation (TTM) 10

Metric	2025	2024	2023	2022	2021	2020
Revenue TTM	$521M	$337M	$186M	$77M	$19M	$0
Net Income TTM	$-23M	$-88M	$-163M	$-136M	$-84M	$-103M
Market Cap	$4.10B	$2.00B	$1.38B	$721M	$488M	$520M
P/E	-168.1	-22.4	-7.4	-4.9	-5.8	·
P/S	7.9	5.9	7.4	9.4	25.5	·
P/B	13.0	8.9	5.5	5.1	4.1	3.0
P / Tangible Book	76.2	·	·	8.7	4.8	3.0
P / Cash Flow	73.4	193.6	-19.4	-6.0	-3.7	-5.8
P / FCF	74.7	214.2	-19.4	-6.0	-3.7	-5.8
Earnings Yield	-0.60%	-4.5%	-13.6%	-20.6%	-17.4%	·

Income Statement 14

Metric	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Revenue	$176M	$160M	$149M	$133M	$128M	$112M	$99M	$90M	$78M	$69M	$70M	$48M	$37M	$32M	$28M	$19M
SG&A Expense	$81M	$96M	$74M	$62M	$63M	$58M	$57M	$51M	$49M	$46M	$46M	$37M	$33M	$30M	$26M	$23M
Operating Expenses	$219M	$949M	$153M	$130M	$133M	$127M	$124M	$103M	$102M	$96M	$102M	$73M	$62M	$59M	$62M	$52M
Operating Income	$-43M	$-789M	$-5M	$3M	$-5M	$-15M	$-24M	$-13M	$-24M	$-26M	$-33M	$-25M	$-24M	$-27M	$-34M	$-33M
Interest Income	$4M	$3M	$3M	$3M	$3M	$3M	$3M	$3M	$3M	$4M	$4M	$4M	$4M	$2M	$2M	$1M
Other Non-op	$-24M	$0	$-218.0K	$395.0K	$86.0K	$2M	$231.0K	$-1M	$312.0K	$2M	$-3M	$1M	$-274.0K	$-811.0K	$-588.0K	$-192.0K
Pretax Income	$-66M	$-790M	$-5M	$3M	$-5M	$-14M	$-24M	$-14M	$-24M	$-25M	$-35M	$-23M	$-74M	$-30M	$-36M	$-36M
Income Tax	$2M	$475.0K	$767.0K	$-262.0K	$402.0K	$1M	$-576.0K	$347.0K	$635.0K	$624.0K	$225.0K	$249.0K	$316.0K	$201.0K	$140.0K	$13.0K
Net Income	$-67M	$-790M	$-6M	$3M	$-6M	$-15M	$-24M	$-14M	$-25M	$-25M	$-36M	$-24M	$-74M	$-30M	$-36M	$-36M
EPS (Basic)	$-1.06	$-13.43	$-0.11	$0.06	$-0.12	$-0.30	$-0.49	$-0.30	$-0.52	$-0.54	$-0.69	$-0.57	$-1.94	$-0.80	$-0.98	$-1.02
EPS (Diluted)	$-1.06	$-13.43	$-0.10	$0.05	$-0.12	$-0.30	$-0.49	$-0.30	$-0.52	$-0.54	$-0.69	$-0.57	$-1.94	$-0.80	$-0.99	$-1.02
Shares (Basic)	63,374,183	58,851,021	·	50,639,231	49,726,823	48,889,058	·	47,782,619	47,235,080	46,927,550	·	41,098,920	38,107,334	37,675,306	·	34,927,790
Shares (Diluted)	63,374,183	58,851,021	·	56,993,841	49,726,823	48,889,058	·	47,782,619	47,235,080	46,927,550	·	41,098,920	38,107,334	37,675,306	·	34,927,790
EBITDA	$-43M	$-783M	·	$3M	$-5M	$-9M	·	$-13M	$-24M	$-21M	·	$-25M	$-24M	$-26M	·	$-33M

Balance Sheet 23

Metric	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Cash & Equivalents	$331M	$325M	$297M	$282M	$228M	$212M	$223M	$223M	$233M	$303M	·	$303M	$297M	$49M	·	$36M
Short-term Investments	$108M	$61M	$87M	$94M	$76M	$66M	$58M	$61M	$45M	·	·	$3M	$33M	$83M	·	$150M
Receivables	$145M	$133M	$123M	$107M	$107M	$96M	$78M	$69M	$60M	$55M	·	$48M	$35M	$25M	·	$16M
Inventory	$26M	$26M	$25M	$24M	$23M	$22M	$22M	$22M	$20M	$22M	·	$22M	$9M	$7M	·	$7M
Prepaid Expense	$27M	$25M	$18M	$24M	$19M	$15M	$12M	$12M	$9M	$10M	·	$12M	$10M	$9M	·	$7M
Current Assets	$636M	$569M	$550M	$531M	$453M	$411M	$393M	$387M	$368M	$389M	·	$389M	$384M	$172M	·	$216M
PP&E (Net)	$2M	$2M	$2M	$1M	$1M	$1M	$1M	$1M	$1M	$501.0K	·	$787.0K	$866.0K	$877.0K	·	$795.0K
Accum. Depreciation	·	·	$1M	·	·	·	$700.0K	·	·	·	·	·	·	·	·	·
Intangibles	$247M	$254M	$261M	$232M	$238M	$244M	$250M	$256M	$262M	$257M	·	$258M	$56M	$58M	·	$45M
Other Non-current Assets	$22M	$16M	$12M	$10M	$7M	$5M	$5M	$5M	$4M	$4M	·	$2M	$1M	$1M	·	$2M
Total Assets	$1.04B	$891M	$843M	$785M	$726M	$690M	$671M	$668M	$661M	$652M	·	$651M	$444M	$334M	·	$364M
Accounts Payable	$23M	$59M	$10M	$12M	$18M	$12M	$15M	$10M	$10M	$16M	·	$7M	$14M	$6M	·	$11M
Accrued Liabilities	·	·	$196M	·	·	·	$112M	$105M	$101M	$90M	·	$66M	$43M	$40M	·	$38M
Current Liabilities	$223M	$273M	$206M	$160M	$145M	$128M	$127M	$116M	$112M	$106M	·	$75M	$58M	$49M	·	$51M
Capital Leases	$10M	$11M	$8M	$7M	$8M	$7M	$8M	$8M	$8M	$328.0K	·	$868.0K	$1M	$1M	·	$1M
Other Non-current Liabilities	$11M	$6M	$5M	$16M	$9M	$14M	$3M	$4M	$4M	$4M	·	$7.0K	$10.0K	$772.0K	·	$4M
Total Liabilities	$1.06B	$648M	$528M	$493M	$471M	$457M	$445M	$436M	$432M	$417M	·	$382M	$365M	$192M	·	$195M
Common Stock	$6.0K	$6.0K	$5.0K	$5.0K	$5.0K	$5.0K	$5.0K	$5.0K	$5.0K	$5.0K	·	$5.0K	$4.0K	$4.0K	·	$4.0K
Retained Earnings	$-1.52B	$-1.46B	$-668M	$-662M	$-665M	$-659M	$-644M	$-620M	$-606M	$-582M	·	$-521M	$-497M	$-423M	·	$-356M
AOCI	$-674.0K	$-28.0K	$351.0K	$37.0K	$352.0K	$-258.0K	$-373.0K	$920.0K	$-477.0K	$-13.0K	·	$-1M	$76.0K	$136.0K	·	$-413.0K
Stockholders' Equity	$-10M	$242M	$315M	$292M	$255M	$233M	$226M	$232M	$229M	$235M	$249M	$269M	$79M	$141M	$142M	$169M
Liabilities + Equity	$1.04B	$891M	$843M	$785M	$726M	$690M	$671M	$668M	$661M	$652M	·	$651M	$444M	$334M	·	$364M
Shares Outstanding	64,754,699	60,926,165	51,896,391	51,314,176	50,058,392	49,451,223	48,338,096	47,968,121	47,571,847	47,061,106	·	46,595,745	38,222,058	38,012,247	·	36,813,754

Cash Flow 13

Metric	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
D&A	$7M	$7M	$6M	$6M	$6M	$6M	$6M	$6M	$6M	$6M	$5M	$3M	$1M	$1M	$1M	$1M
Stock-based Comp	$31M	$36M	$19M	$18M	$18M	$16M	$13M	$12M	$12M	$11M	$10M	$8M	$8M	$9M	$7M	$7M
Amort. of Intangibles	$7M	$7M	$6M	$6M	$6M	$6M	$6M	$6M	$6M	$6M	$5M	$3M	$1M	$1M	$1M	$1M
Other Non-cash	·	$518M	·	·	·	$-9M	·	·	·	$23M	·	·	·	$-14M	·	·
Operating Cash Flow	$-44M	$-229M	$6M	$40M	$12M	$-2M	$-5M	$4M	$-4M	$15M	$-17M	$-18M	$-2M	$-19M	$-34M	$-26M
CapEx	$23.0K	$664.0K	$600.0K	$187.0K	$126.0K	$41.0K	$20.0K	$181.0K	$779.0K	$13.0K	$0	$0	$68.0K	$41.0K	$242.0K	$19.0K
Investing Cash Flow	$-160M	$-12M	$1M	$-2M	$-7M	$-16M	$641.0K	$-18M	$-73M	$-13.0K	$-2M	$-183M	$36M	$27M	$27M	$-80M
Stock Issued	·	·	·	·	·	·	$0	$0	$0	$0	$0	$0	$0	$14M	$0	$0
Net Stock Activity	·	·	·	·	·	·	·	·	·	$0	·	·	·	$14M	·	·
Financing Cash Flow	$211M	$270M	$9M	$16M	$9M	$6M	$5M	$4M	$7M	$1M	$2M	$207M	$115M	$13M	$-329.0K	$86M
Net Change in Cash	$6M	$28M	$16M	$54M	$16M	$-11M	$-466.0K	$-10M	$-69M	$17M	$-17M	$6M	$148M	$21M	$-8M	$-20M
Taxes Paid	$907.0K	$220.0K	$6.0K	$504.0K	$1M	$162.0K	$233.0K	$432.0K	$200.0K	$139.0K	$125.0K	$0	$0	$0	·	·
Free Cash Flow	·	$-229M	·	·	·	$-2M	·	·	·	$15M	·	·	·	$-34M	·	·

Profitability 7

Metric	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Operating Margin	-24.1%	-493.8%	·	2.0%	-3.9%	-13.6%	·	-14.0%	-31.1%	-38.2%	·	-52.7%	-64.7%	-85.9%	·	-175.1%
Net Margin	-38.1%	-494.2%	·	2.2%	-4.6%	-13.2%	·	-15.8%	-31.6%	-36.5%	·	-49.4%	-197.4%	-95.3%	·	-190.1%
Pretax Margin	-37.2%	-493.9%	·	2.0%	-4.3%	-12.2%	·	-15.4%	-30.8%	-35.6%	·	-48.9%	-196.6%	-94.7%	·	-190.1%
EBITDA Margin	-24.1%	-489.5%	·	2.0%	-3.9%	-8.2%	·	-14.0%	-31.1%	-30.0%	·	-52.7%	-64.7%	-81.7%	·	-175.1%
ROA	-7.6%	-100.0%	·	0.40%	-0.85%	-2.2%	·	-2.2%	-4.5%	-5.1%	·	-4.7%	-20.0%	-9.8%	·	-11.9%
ROE	-54.9%	-332.2%	·	1.1%	-2.4%	-6.3%	·	-5.7%	-16.0%	-13.5%	·	-10.8%	-78.2%	-24.1%	·	-31.6%
ROIC	418.7%	-325.8%	·	0.98%	-2.1%	-7.0%	·	-5.6%	-10.9%	-11.6%	·	-9.4%	-31.0%	-19.4%	·	-19.4%

Liquidity & Solvency 2

Metric	Trend	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Current Ratio		2.9	2.1	·	3.3	3.1	3.2	·	3.3	3.3	3.7	·	5.2	6.6	3.5	·	4.2
Quick Ratio		2.6	1.9	·	3.0	2.8	2.9	·	3.0	3.0	3.4	·	4.7	6.3	3.2	·	3.9

Efficiency 2

Metric	Trend	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Asset Turnover		0.2	0.2	·	0.2	0.2	0.2	·	0.1	0.1	0.1	·	0.1	0.1	0.1	·	0.1
Receivables Turnover		1.4	1.4	·	1.5	1.5	1.5	·	1.6	1.6	1.7	·	1.5	1.5	1.9	·	2.3

Per Share 5

Metric	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Book Value / Share	$-0.16	$3.98	·	$5.69	$5.10	$4.72	·	$4.84	$4.81	$4.99	·	$5.77	$2.06	$3.71	·	$4.60
Revenue / Share	$2.78	$2.72	·	$2.33	$2.57	$2.28	·	$1.89	$1.65	$1.48	·	$1.16	$0.98	$0.84	·	$0.54
Cash Flow / Share	·	$-3.89	·	·	·	$-0.04	·	·	·	$0.32	·	·	·	$-0.90	·	·
Cash / Share	$5.11	$5.33	·	$5.50	$4.56	$4.28	·	$4.65	$4.90	$6.44	·	$6.50	$7.78	$1.30	·	$0.97
EPS (TTM)	$-14.54	$-13.60	·	$-0.86	$-1.21	$-1.61	·	$-2.05	$-2.32	$-3.74	·	$-4.30	$-4.75	$-3.65	·	$-1.12

Valuation (TTM) 9

Metric	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Revenue TTM	$618M	$570M	·	$472M	$429M	$379M	·	$307M	$264M	$224M	·	$145M	$116M	$96M	·	$52M
Net Income TTM	$-860M	$-799M	·	$-41M	$-59M	$-77M	·	$-100M	$-109M	$-159M	·	$-164M	$-176M	$-129M	·	$-42M
Market Cap	$7.58B	$5.63B	·	$3.76B	$2.55B	$2.23B	·	$1.87B	$1.63B	$1.18B	·	$1.47B	$989M	$913M	·	$773M
P/E	-8.1	-6.8	·	-85.2	-42.1	-28.0	·	-19.0	-14.7	-6.7	·	-7.3	-5.4	-6.6	·	-18.8
P/S	12.3	9.9	·	8.0	5.9	5.9	·	6.1	6.2	5.3	·	10.2	8.5	9.5	·	14.8
P/B	-727.4	23.2	·	12.9	10.0	9.6	·	8.1	7.1	5.0	·	5.5	12.6	6.5	·	4.6
P / Tangible Book	·	·	·	62.5	147.4	·	·	·	·	·	·	137.1	44.6	10.9	·	6.2
P / Cash Flow	·	-24.6	·	·	·	-1136.0	·	·	·	77.7	·	·	·	-27.0	·	·
Earnings Yield	-12.4%	-14.7%	·	-1.2%	-2.4%	-3.6%	·	-5.3%	-6.8%	-14.9%	·	-13.6%	-18.4%	-15.2%	·	-5.3%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16

Metric	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Revenue	$521M	$337M	$186M	$77M	$19M
Operating Margin %	-4.2%	-26.0%	-58.6%	-170.3%	-906.1%
Net Income	$-23M	$-88M	$-163M	$-136M	$-84M
Diluted EPS	$-0.47	$-1.85	$-4.00	$-4.02	$-2.77

Metric	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Current Ratio	2.7	3.1	4.5	2.9	3.9
Quick Ratio	2.5	2.8	4.1	2.7	3.8

Metric	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Free Cash Flow	$55M	$9M	$-71M	$-120M	$-133M

Institutional owners (13F) 346 filers · $8.2B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 346

Value held $8.2B

New positions 62

Exited positions 41

Institutional activity — Q2 2026 vs prior quarter

New positions	Exited positions	Increased	Decreased	Net shares change
62 (-11 vs prior Q)	41 (+10 vs prior Q)	126 (+12 vs prior Q)	98 (+11 vs prior Q)	-2.9M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution	Value	Shares	% of tracked 13F	Type
Frazier Life Sciences Management, L.P.	$899,060,606	7,679,684	11.02%	Shares
JANUS HENDERSON GROUP PLC	$641,764,403	6,945,813	7.86%	Shares
BlackRock, Inc.	$513,944,677	4,390,063	6.30%	Shares
FMR LLC	$429,683,688	3,670,314	5.26%	Shares
VANGUARD PORTFOLIO MANAGEMENT LLC	$278,277,614	2,377,019	3.41%	Shares
VANGUARD CAPITAL MANAGEMENT LLC	$263,888,541	2,254,109	3.23%	Shares
STATE STREET CORP	$254,122,561	2,170,689	3.11%	Shares
VANGUARD GROUP INC	$205,065,069	2,596,089	2.51%	Shares
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	$164,453,029	1,404,741	2.02%	Shares
GEODE CAPITAL MANAGEMENT, LLC	$163,213,962	1,393,908	2.00%	Shares
Invesco Ltd.	$159,693,314	1,364,084	1.96%	Shares
WELLINGTON MANAGEMENT GROUP LLP	$153,360,177	1,309,987	1.88%	Shares
EVENTIDE ASSET MANAGEMENT, LLC	$146,202,247	1,248,389	1.79%	Shares
TANG CAPITAL MANAGEMENT LLC	$144,701,681	1,236,027	1.77%	Shares
Capital World Investors	$135,037,904	1,153,480	1.65%	Shares
FRANKLIN RESOURCES INC	$134,954,787	1,152,770	1.65%	Shares
NOVO HOLDINGS A/S	$131,703,750	1,125,000	1.61%	Shares
TCG Crossover Management, LLC	$124,334,076	1,062,049	1.52%	Shares
BVF INC/IL	$123,629,081	1,056,027	1.51%	Shares
Polar Capital Holdings Plc	$98,985,495	845,524	1.21%	Shares
Rock Springs Capital Management LP	$93,438,835	798,145	1.14%	Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	$88,042,000	752,044	1.08%	Shares
AMERIPRISE FINANCIAL INC	$85,074,348	726,694	1.04%	Shares
TWO SIGMA INVESTMENTS, LP	$80,815,528	690,318	0.99%	Shares
Bank of New York Mellon Corp	$78,433,863	669,974	0.96%	Shares
Clearbridge Investments, LLC	$74,893,623	639,734	0.92%	Shares
BNP PARIBAS FINANCIAL MARKETS	$70,994,409	606,427	0.87%	Shares
Woodline Partners LP	$66,483,351	567,894	0.81%	Shares
BANK OF AMERICA CORP /DE/	$65,761,029	561,724	0.81%	Shares
GOLDMAN SACHS GROUP INC	$64,373,750	549,874	0.79%	Shares
Pictet Asset Management Holding SA	$61,630,682	526,443	0.76%	Shares
Balyasny Asset Management L.P.	$57,267,132	489,170	0.70%	Shares
EMERALD ADVISERS, LLC	$54,823,296	468,295	0.67%	Shares
NORTHERN TRUST CORP	$52,919,855	452,036	0.65%	Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	$52,614,653	449,429	0.64%	Shares
BAKER BROS. ADVISORS LP	$52,210,293	445,975	0.64%	Shares
LOOMIS SAYLES & CO L P	$51,936,466	443,636	0.64%	Shares
RENAISSANCE TECHNOLOGIES LLC	$51,766,598	442,185	0.63%	Shares
FEDERATED HERMES, INC.	$51,116,860	436,635	0.63%	Shares
NEXT CENTURY GROWTH INVESTORS LLC	$49,194,335	420,213	0.60%	Shares
Connor, Clark & Lunn Investment Management Ltd.	$49,176,775	420,063	0.60%	Shares
BOONE CAPITAL MANAGEMENT LLC	$48,659,092	415,641	0.60%	Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/	$45,021,610	384,570	0.55%	Shares
UBS Group AG	$44,458,503	379,760	0.54%	Shares
Candriam S.C.A.	$43,992,694	376,143	0.54%	Shares
MORGAN STANLEY	$41,138,902	351,404	0.50%	Shares
ADAGE CAPITAL PARTNERS GP, L.L.C.	$40,974,500	350,000	0.50%	Shares
Palo Alto Investors LP	$40,834,953	348,808	0.50%	Shares
VANGUARD FIDUCIARY TRUST CO	$40,767,286	348,230	0.50%	Shares
Octagon Capital Advisors LP	$39,675,023	338,900	0.49%	Shares

Show all 346 institutional owners →

Activists & 5%+ owners 7 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer	Filed	Stake	Status	Purpose	Filing
Frazier Life Sciences IX, L.P., FHMLS IX, L.P., FHMLS IX, L.L.C., Frazier Life Sciences X, L.P., FHMLS X, L.P., FHMLS X, L.L.C., Frazier Life Sciences Public Fund, L.P., FHMLSP, L.P., FHMLSP, L.L.C., Frazier Life Sciences XI, L.P., FHMLS XI, L.P., FHMLS XI, L.L.C., Frazier Life Sciences XII, L.P., FHMLS XII, L.P., FHMLS XII, L.L.C., James N. Topper, Patrick J. Heron ×9 filings	Jan. 27, 2026	6.80%	Amendment	Passive investment	SEC
	Dec. 29, 2023	·	Initial filing	·	SEC
New Enterprise Associates 16, L.P., NEA Partners 16, L.P., NEA 16 GP, LLC, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad H. Makhzoumi, Scott D. Sandell, Paul Walker ×2 filings	June 23, 2023	·	Initial filing	·	SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person	Dec. 1, 2022	·	Initial filing	·	SEC
Novo Holdings A/S ×7 filings	Aug. 18, 2022	·	Initial filing	·	SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person	Dec. 22, 2020	·	Initial filing	·	SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person	Aug. 1, 2019	·	Initial filing	Passive investment	SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 33 insiders · 9 officers · 12 directors

19

Insider	Role	Last activity	Shares owned	Buys 12m	Sells 12m	Net 12m
Christopher Peetz	CHIEF EXECUTIVE OFFICER	Sept. 1, 2026 M	194,440	0	19	$-16,289,473
Eric Bjerkholt	CHIEF FINANCIAL OFFICER	Sept. 11, 2026 M	44,745	0	12	$-3,562,112
Ian Clements	Chief Financial Officer	Nov. 10, 2022 A	30,011	0	0	$0
Peter Radovich	PRESIDENT AND COO	June 5, 2026 M	57,260	0	4	$-2,315,469
Jolanda Howe	SVP, GLOBAL CONTROLLER	Sept. 2, 2026 S	616	0	9	$-5,553,171
Joanne Quan	CHIEF MEDICAL OFFICER	March 15, 2026 M	18,864	0	3	$-1,464,161
Pamela Vig	CHIEF SCIENTIFIC OFFICER	June 24, 2024 M	27,406	0	0	$0
Lara Longpre	CHIEF DEVELOPMENT OFFICER	Jan. 9, 2023 S	104,369	0	0	$0
Edwin Jonathan Tucker	Chief Medical Officer	Nov. 10, 2021 A	45,838	0	0	$0
Lon Cardon	Director	June 15, 2026 A	9,680	0	0	$0
William Fairey	Director	June 15, 2026 A	2,500	0	0	$0
Saira Ramasastry	Director	June 15, 2026 A	0	0	9	$-1,917,580
Laurent Fischer	Director	June 15, 2026 A	10,727	0	0	$0
Laura Brege	Director	June 15, 2026 A	15,703	0	0	$0
Patrick J. Heron	Director	June 15, 2026 A	459,010	1	0	$8,999,984
Timothy P Walbert	Director	June 15, 2026 A	9,680	0	0	$0
Michael G Grey	Director	June 15, 2026 A	0	0	3	$-11,100,000
Niall O'Donnell, Ph.D.	Director	Nov. 15, 2022 S	1,621,118	0	0	$0
Carol L Brosgart	Director	June 2, 2022 A	·	0	0	$0
Edward T. Mathers	Director	June 2, 2022 A	·	0	0	$0
Carmen Chang	10% owner	June 13, 2023 J	135	0	0	$0
New Enterprise Associates 16, L.P.	10% owner	June 13, 2023 J	2,186,243	0	0	$0
Mohamad Makhzoumi	10% owner	June 13, 2023 J	11,348	0	0	$0
Ali Behbahani	10% owner	June 13, 2023 J	135	0	0	$0
Anthony A. Florence, Jr.	10% owner	June 13, 2023 J	11,348	0	0	$0
Paul Walker	10% owner	June 13, 2023 J	114	0	0	$0
Forest Baskett	10% owner	June 13, 2023 J	1,548	0	0	$0
Scott D. Sandell	10% owner	June 13, 2023 J	11,348	0	0	$0
Peter W. Sonsini	10% owner	July 22, 2019 C	4,186,243	0	0	$0
Novo Holdings A/S	10% owner	July 22, 2019 C	2,445,147	0	0	$0
Joshua Makower	10% owner	July 22, 2019 C	4,186,243	0	0	$0
David M Mott	10% owner	July 22, 2019 C	4,186,243	0	0	$0
Peter J Barris	10% owner	July 22, 2019 C	4,186,243	0	0	$0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 37 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund	Weight	Units	As of	Source
BBP · ETFis Series Trust I	1.47%	13,661 NS	July 31, 2026	N-PORT
LABU · Direxion Shares ETF Trust	0.77%	35,899 NS	July 31, 2026	N-PORT
FNY · First Trust Exchange-Traded AlphaDE…	0.58%	31,362 NS	July 31, 2026	N-PORT
ESSC · Strategy Shares	0.39%	1,309 NS	July 31, 2026	N-PORT
IBB · iShares Trust	0.37%	379,636 SH	Sept. 11, 2026	Daily
IBBQ · Invesco Exchange-Traded Fund Trust …	0.36%	4,593 SH	Oct. 2, 2026	Daily
VTWG · VANGUARD SCOTTSDALE FUNDS	0.33%	50,804 SH	Aug. 19, 2026	Daily
IWO · iShares Trust	0.31%	445,371 SH	Sept. 11, 2026	Daily
FNX · First Trust Exchange-Traded AlphaDE…	0.27%	35,193 NS	July 31, 2026	N-PORT
BKSE · BNY Mellon ETF Trust	0.24%	2,013 NS	July 31, 2026	N-PORT
PWS · Pacer Funds Trust	0.22%	490 NS	July 31, 2026	N-PORT
ROSC · Lattice Strategies Trust	0.20%	1,161 NS	July 31, 2026	N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr…	0.18%	12,040 NS	July 31, 2026	N-PORT
FAD · First Trust Exchange-Traded AlphaDE…	0.17%	9,414 NS	July 31, 2026	N-PORT
VBK · VANGUARD INDEX FUNDS	0.17%	686,321 SH	Aug. 19, 2026	Daily
VTWO · VANGUARD SCOTTSDALE FUNDS	0.17%	273,231 SH	Aug. 19, 2026	Daily
RSSL · Global X Funds	0.16%	22,732 NS	July 31, 2026	N-PORT
IWM · iShares Trust	0.16%	1,212,070 SH	Sept. 11, 2026	Daily
ISCG · iShares Trust	0.15%	14,024 SH	Sept. 11, 2026	Daily
FSMD · FIDELITY COVINGTON TRUST	0.14%	32,141 NS	July 31, 2026	N-PORT
VFMO · VANGUARD WELLINGTON FUND	0.11%	18,506 SH	Aug. 19, 2026	Daily
VB · VANGUARD INDEX FUNDS	0.07%	1,188,816 SH	Aug. 19, 2026	Daily
VHT · VANGUARD WORLD FUND	0.07%	126,877 SH	Aug. 19, 2026	Daily
FHLC · FIDELITY COVINGTON TRUST	0.06%	20,071 NS	July 31, 2026	N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe…	0.06%	1,996 SH	Oct. 2, 2026	Daily
VXF · VANGUARD INDEX FUNDS	0.06%	552,499 SH	Aug. 19, 2026	Daily
ESML · iShares Trust	0.05%	14,579 SH	Sept. 11, 2026	Daily
WSML · iShares Trust	0.04%	2,608 SH	Sept. 11, 2026	Daily
PRFZ · Invesco Exchange-Traded Fund Trust	0.04%	12,440 SH	Oct. 2, 2026	Daily
VTI · VANGUARD INDEX FUNDS	0.01%	1,648,584 SH	Aug. 19, 2026	Daily
VTHR · VANGUARD SCOTTSDALE FUNDS	0.01%	3,912 SH	Aug. 19, 2026	Daily
ITOT · iShares Trust	0.01%	62,879 SH	Sept. 11, 2026	Daily
IWV · iShares Trust	0.01%	12,733 SH	Sept. 11, 2026	Daily
TILT · FlexShares Trust	0.01%	1,296 NS	July 31, 2026	N-PORT
ISCB · iShares Trust	·	1,994 SH	Sept. 11, 2026	Daily
SMLF · iShares Trust	·	54,129 SH	Sept. 11, 2026	Daily
SMMV · iShares Trust	·	7,592 SH	Aug. 19, 2026	Daily

MIRM Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21

rating · 20 analysts BUY

Median target $138.50 +67.0%

8 40.0% Strong Buy

11 55.0% Buy

1 5.0% Hold

0 0.0% Sell

0 0.0% Strong Sell

12-Month Price Target

14 analysts · 2026-09-29

Mean target $145.79 +75.8%

← Below all targets Current price $82.93

Low$118.00 Mean$145.79 High$195.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker	Market Cap	P/E	Rev YoY	Net Margin	ROE	Gross Margin
MIRM	$4.10B	-168.1	54.7%	-4.5%	-8.2%	·
SRRK	$4.78B	-13.4	·	·	-157.9%	·
KOD	$1.73B	-6.5	·	·	-202.0%	·
ORKA	$1.48B	-3.3	·	·	-25.9%	·
COGT	$5.72B	-16.4	·	·	-83.1%	·
TVTX	$3.47B	-131.8	110.5%	-5.2%	-34.6%	·
PTCT	$6.19B	9.8	114.5%	39.4%	-331.5%	·
ERAS	$1.06B	-8.5	·	·	-35.7%	·
DNTH	$1.78B	-9.8	-67.3%	-7973.3%	-40.8%	·

Latest News Recent headlines mentioning this company

23

Mirum Pharma (MIRM) Earnings Call Transcript Yahoo Finance · 6 months ago Hedge Fund Boone Capital Initiated a Stake in HealthEquity. Is the Stock a Buy? Yahoo Finance · 6 months, 2 weeks ago

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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MIRM Mirum Pharmaceuticals, Inc. - common stock