Insider at

04

Insider transactions

05
0 buys (P) 2 sells (S) Net: $-5,249,138 + 44 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

44 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
Dec. 19, 2025 TYRA S 10b5-1 10,000 $25.00 $250,000 3,823,425 Indirect -0.26% Disposed -18.3% (price as of 2026-10-02)
Nov. 21, 2025 TYRA S 10b5-1 246,871 $20.25 $4,999,138 3,833,425 Indirect -6.05% Disposed 0.9% (price as of 2026-10-02)
Sept. 17, 2021 TYRA P 156,250 $16.00 $2,500,000 4,080,296 Indirect +3.98% Acquired 27.7% (price as of 2026-10-02)
July 29, 2021 VIR S 10b5-1 2,348 $37.58 $88,238 36,030 Direct -6.12% Disposed -70.3% (price as of 2026-10-02)
July 29, 2021 VIR S 10b5-1 9,322 $36.63 $341,465 38,378 Direct -19.54% Disposed -69.5% (price as of 2026-10-02)
July 15, 2021 VIR S 10b5-1 11,670 $35.56 $414,985 46,029 Direct -20.23% Disposed -68.6% (price as of 2026-10-02)
July 1, 2021 VIR S 10b5-1 890 $46.22 $41,136 57,699 Direct -1.52% Disposed -75.8% (price as of 2026-10-02)
July 1, 2021 VIR S 10b5-1 5,986 $45.23 $270,747 58,589 Direct -9.27% Disposed -75.3% (price as of 2026-10-02)
July 1, 2021 VIR S 10b5-1 4,794 $44.31 $212,422 64,575 Direct -6.91% Disposed -74.8% (price as of 2026-10-02)
June 17, 2021 VIR S 10b5-1 11,670 $43.95 $512,896 69,369 Direct -14.40% Disposed -74.6% (price as of 2026-10-02)
June 3, 2021 VIR S 10b5-1 11,670 $44.56 $520,015 81,039 Direct -12.59% Disposed -74.9% (price as of 2026-10-02)
May 20, 2021 VIR S 10b5-1 9,095 $44.77 $407,183 89,335 Direct -9.24% Disposed -75.1% (price as of 2026-10-02)
May 20, 2021 VIR S 10b5-1 2,575 $43.57 $112,193 98,430 Direct -2.55% Disposed -74.4% (price as of 2026-10-02)
May 1, 2020 VIR S 15,758 $27.90 $439,648 74,234 Direct -17.51% Disposed -60.0% (price as of 2026-10-02)
May 1, 2020 VIR S 2,700 $28.60 $77,220 71,534 Direct -3.64% Disposed -60.9% (price as of 2026-10-02)
June 24, 2015 GKOS P 5,000 $18.00 $90,000 5,000 Direct · Acquired 809.7% (price as of 2026-10-02)
Dec. 12, 2006 VNDA S 12,900 $25.62 $330,498 21,068 Indirect -37.98% Disposed -81.9% (price as of 2026-10-02)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
May 28, 2026 TYRA Stock Option (Right to Buy) Common Stock (13,160) $32.68 May 27, 2036 13,160 Acquired
May 27, 2026 VIR Stock Option (Right to Buy) Common Stock (16,000) $9.10 May 26, 2036 16,000 Acquired
May 30, 2025 VIR Stock Option (Right to Buy) Common Stock (16,000) $4.94 May 29, 2035 16,000 Acquired
May 29, 2025 TYRA Stock Option (Right to Buy) Common Stock (22,200) $9.25 May 28, 2035 22,200 Acquired
May 30, 2024 VIR Stock Option (Right to Buy) Common Stock (16,000) $10.39 May 29, 2034 16,000 Acquired
May 29, 2024 TYRA Stock Option (Right to Buy) Common Stock (18,600) $15.94 May 28, 2034 18,600 Acquired
May 31, 2023 TYRA Stock Option (Right to Buy) Common Stock (14,500) $14.47 May 30, 2033 14,500 Acquired
May 22, 2023 VIR Stock Option (Right to Buy) Common Stock (12,054) $25.74 May 21, 2033 12,054 Acquired
June 13, 2022 TYRA Stock Option (Right to Buy) Common Stock (14,500) $5.38 June 12, 2032 14,500 Acquired
May 23, 2022 VIR Stock Option (Right to Buy) Common Stock (12,810) $24.14 May 22, 2032 12,810 Acquired
Sept. 17, 2021 TYRA Series A Preferred Stock Common Stock (3,148,365) · · 1,212,122 Disposed
Sept. 17, 2021 TYRA Series B Preferred Stock Common Stock (662,752) · · 255,160 Disposed
May 21, 2021 VIR Stock Option (Right to Buy) Common Stock (6,748) $45.28 May 20, 2031 6,748 Acquired
May 21, 2020 VIR Stock Option (Right to Buy) Common Stock (24,355) $37.06 May 20, 2030 24,355 Acquired
May 21, 2020 VIR Stock Option (Right to Buy) Common Stock (28,888) $37.06 May 21, 2030 28,888 Acquired
Oct. 16, 2019 VIR Series B Convertible Preferred Stock Common Stock (277,777) · · 277,777 Disposed
Oct. 16, 2019 VIR Series A-2 Convertible Preferred Stock Common Stock (60,822) · · 60,822 Disposed
Oct. 16, 2019 VIR Series A-1 Convertible Preferred Stock Common Stock (1,666,666) · · 1,666,666 Disposed
April 18, 2006 VNDA Series B Preferred Stock Common Stock (33,968) · · 112,431 Disposed
April 18, 2006 VNDA Series B Preferred Stock Common Stock (3,169,626) · · 10,490,691 Disposed

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 8 holdings

07

Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Sept. 14, 2021 TYRA Common Stock 112,929 Indirect
Sept. 14, 2021 TYRA Series A Preferred Stock→ Common Stock (3,148,365) 3,148,365 Indirect
Sept. 14, 2021 TYRA Series B Preferred Stock→ Common Stock (662,752) 662,752 Indirect
Oct. 10, 2019 VIR Series A-1 Convertible Preferred Stock→ Common Stock (1,666,666) 1,666,666 Indirect
Oct. 10, 2019 VIR Series A-2 Convertible Preferred Stock→ Common Stock (60,822) 60,822 Direct
Oct. 10, 2019 VIR Series B Convertible Preferred Stock→ Common Stock (277,777) 277,777 Indirect
April 12, 2006 VNDA Series B Preferred Stock→ Common Stock · Indirect
April 12, 2006 VNDA Series B Preferred Stock→ Common Stock · Indirect