VNDA Vanda Pharmaceuticals Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$5.58
Price · Aug 19, 2026
Fundamentals as of Aug 6, 2026

VNDA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$5.58
Market Cap
$335M
P/E (TTM)
-1.5
EPS (TTM)
$-3.74
Revenue (TTM)
$216M
Div Yield
ROE
-54.2%
Debt/Equity
52W Range
$4 – $10

VNDA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $216M
10-point trend, +48.0%
2016-12-31 2025-12-31
EPS $-3.74
10-point trend, -812.2%
2016-12-31 2025-12-31
Free Cash Flow $-110M
10-point trend, -1061.3%
2016-12-31 2025-12-31
Margins -102.0%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
VNDA
Peer Median
P/E (TTM)
5-point trend, -108.7%
-1.5
4.8
P/S (TTM)
5-point trend, -26.1%
1.6
25.4
P/B
5-point trend, -8.3%
1.0
1.8
Price / FCF
5-point trend, -134.3%
-3.0

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
VNDA
Peer Median
Operating Margin
5-point trend, -545.8%
-70.0%
Net Profit Margin
5-point trend, -926.7%
-102.0%
-892.4%
ROA
5-point trend, -754.9%
-38.5%
-40.4%
ROE
5-point trend, -916.3%
-54.2%
-52.2%
ROIC
5-point trend, -1225.1%
-73.5%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
VNDA
Peer Median
Current Ratio
5-point trend, -62.8%
2.4
6.5
Quick Ratio
5-point trend, -15.4%
1.0

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
VNDA
Peer Median
Revenue YoY
5-point trend, -19.6%
8.7%
Revenue CAGR 3Y
5-point trend, -19.6%
-5.3%
Revenue CAGR 5Y
5-point trend, -19.6%
-2.7%
EPS YoY
5-point trend, -744.8%
-63.6%
Net Income YoY
5-point trend, -765.0%
-60.0%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
VNDA
Peer Median
EPS (Diluted)
5-point trend, -744.8%
$-3.74

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
VNDA
Peer Median

VNDA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 10 analysts
  • Strong Buy 2 20.0%
  • Buy 6 60.0%
  • Hold 2 20.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

4 analysts · 2026-08-17
Median target $11.50 +106.3%
Mean target $12.19 +118.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.07%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-1.04 $-0.60 -0.44%
March 31, 2026 $-0.82 $-0.70 -0.12%
Dec. 31, 2025 $-0.46 $-1.35 0.89%
Sept. 30, 2025 $-0.38 $-0.46 0.08%
June 30, 2025 $-0.46 $-0.36 -0.10%
March 31, 2025 $-0.50 $-0.61 0.11%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
VNDA $521M -2.4 8.7% -102.0% -54.2%
LYEL $654M -1.9 -41.0% -762355.6% -100.3%
IKT $270M -4.2 111.0% -1299.0% -38.2%
AGEN $111M 10.4% -2.7% 1.0%
FATE $113M -0.9 -51.2% -2051.1% -58.2%
CAMP $318M -2.3 436.5% -2298.5% -183.4%
IRD $140M -2.5 29.1% -349.3% -302.2%
AVXL $771M -16.5 -36.1% -991.4% -47.7%
ELDN $114M -2.9 -69.4%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for VNDA
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +330.9% $216M $199M $193M $254M $269M $248M $227M $193M $165M $146M $110M $50M
Cost of Revenue 2-point trend, +1382.1% · · · · · · · · · · $23M $2M
R&D Expense 12-point trend, +468.2% $109M $74M $77M $86M $75M $56M $49M $44M $39M $29M $29M $19M
SG&A Expense 12-point trend, +181.1% $238M $146M $113M $136M $124M $141M $130M $106M $124M $100M $85M $85M
Operating Expenses 12-point trend, +1120.4% $367M $239M $207M $248M $227M $221M $204M $171M $182M $165M $150M $30M
Operating Income 12-point trend, -853.5% $-151M $-41M $-14M $6M $42M $27M $23M $22M $-17M $-19M $-40M $20M
Pretax Income 12-point trend, -786.8% $-139M $-23M $6M $11M $42M $32M $29M $25M $-15M $-18M $-40M $20M
Income Tax 12-point trend, +81827000.00 $82M $-4M $4M $5M $9M $8M $-87M $138.0K $136.0K $104.0K $0 $0
Net Income 12-point trend, -1192.2% $-220M $-19M $3M $6M $33M $23M $116M $25M $-16M $-18M $-40M $20M
EPS (Basic) 12-point trend, -744.8% $-3.74 $-0.33 $0.04 $0.11 $0.60 $0.43 $2.17 $0.50 $-0.35 $-0.41 $-0.94 $0.58
EPS (Diluted) 12-point trend, -780.0% $-3.74 $-0.33 $0.04 $0.11 $0.58 $0.42 $2.11 $0.48 $-0.35 $-0.41 $-0.94 $0.55
Shares (Basic) 12-point trend, +69.5% 58,930,157 58,149,087 57,380,975 56,461,877 55,548,122 54,427,683 53,137,562 50,859,947 44,735,146 43,449,441 42,250,254 34,774,163
Shares (Diluted) 12-point trend, +60.6% 58,930,157 58,149,087 57,557,911 56,983,171 56,921,836 55,190,802 54,847,060 53,045,257 44,735,146 43,449,441 42,250,254 36,686,723
EBITDA 11-point trend, -276.2% $-151M $-41M $-14M $6M $42M $27M $23M $22M $-17M $-19M $-40M ·
Balance Sheet 24
Annual Balance Sheet data for VNDA
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +39.3% $85M $102M $136M $135M $52M $61M $45M $61M $34M $40M $51M $61M
Receivables 12-point trend, +1393.7% $55M $47M $34M $34M $32M $30M $26M $29M $18M $20M $16M $4M
Inventory 12-point trend, -64.2% $2M $2M $1M $1M $1M $1M $1M $994.0K $840.0K $779.0K $1M $5M
Prepaid Expense 12-point trend, +775.0% $27M $15M $9M $18M $12M $10M $14M $12M $8M $12M $6M $3M
Other Current Assets 4-point trend, +1661.0% · · · · · · · · $3M $2M $979.0K $154.0K
Current Assets 12-point trend, +145.0% $347M $439M $433M $519M $478M $409M $354M $299M $170M $174M $167M $142M
PP&E (Net) 12-point trend, -7.8% $2M $2M $2M $3M $3M $4M $4M $4M $5M $5M $5M $2M
PP&E (Gross) 12-point trend, +256.5% $15M $14M $13M $13M $12M $12M $10M $10M $10M $8M $7M $4M
Accum. Depreciation 12-point trend, +628.0% $13M $12M $11M $10M $9M $8M $7M $5M $4M $3M $2M $2M
Intangibles 12-point trend, +338.1% $117M $114M $121M $19M $20M $22M $23M $25M $26M $28M $39M $27M
Other Non-current Assets · · · · · · · · · · · $28.0K
Total Assets 12-point trend, +184.8% $489M $656M $648M $634M $594M $533M $484M $332M $205M $210M $213M $172M
Accounts Payable 12-point trend, +836.7% $68M $39M $38M $46M $34M $32M $28M $22M $20M $16M $16M $7M
Accrued Liabilities · · · · · · · · · · · $7M
Current Liabilities 12-point trend, +1764.4% $145M $100M $88M $91M $74M $66M $60M $53M $70M $50M $51M $8M
Capital Leases 8-point trend, +2991000.00 $3M $5M $7M $9M $10M $11M $12M $0 · · · ·
Other Non-current Liabilities 12-point trend, +207.4% $10M $10M $9M $7M $4M $3M $843.0K $4M $4M $4M $4M $3M
Total Liabilities 12-point trend, +1385.8% $162M $118M $104M $107M $89M $80M $73M $57M $74M $79M $80M $11M
Common Stock 12-point trend, +43.9% $59.0K $58.0K $58.0K $57.0K $56.0K $55.0K $54.0K $52.0K $45.0K $44.0K $43.0K $41.0K
Retained Earnings 12-point trend, -37.1% $-395M $-174M $-155M $-158M $-164M $-197M $-221M $-336M $-361M $-346M $-328M $-288M
AOCI 12-point trend, +3831.2% $629.0K $74.0K $-30.0K $-1M $-175.0K $239.0K $249.0K $1.0K $-34.0K $58.0K $39.0K $16.0K
Stockholders' Equity 12-point trend, +103.5% $327M $539M $545M $527M $505M $453M $411M $275M $131M $131M $133M $161M
Liabilities + Equity 12-point trend, +184.8% $489M $656M $648M $634M $594M $533M $484M $332M $205M $210M $213M $172M
Shares Outstanding 12-point trend, +42.5% 59,101,630 58,310,644 57,534,499 56,783,764 55,900,855 54,865,092 53,549,612 52,477,593 44,938,133 44,000,614 42,815,291 41,486,361
Cash Flow 13
Annual Cash Flow data for VNDA
Metric Trend 202520242023202220212020201920182017201620152014
D&A · · · · · · · · · · · $530.0K
Stock-based Comp 12-point trend, +61.2% $9M $12M $14M $16M $15M $13M $13M $12M $10M $9M $8M $6M
Deferred Tax 10-point trend, +78410.6% $81M $-6M $-1M $1M $7M $6M $-88M $0 $0 $-104.0K · ·
Amort. of Intangibles 12-point trend, +210.9% $7M $7M $2M $2M $1M $1M $2M $2M $2M $11M $13M $2M
Operating Cash Flow 12-point trend, -34.2% $-109M $-16M $13M $32M $64M $52M $46M $30M $-2M $-8M $12M $-82M
CapEx 12-point trend, +29.8% $998.0K $490.0K $383.0K $679.0K $552.0K $2M $1M $368.0K $2M $1M $3M $769.0K
Investing Cash Flow 9-point trend, +1027.2% $95M $-17M $-12M $50M $-77M $-41M $-68M $-110M $-10M · · ·
Stock Issued 6-point trend, -100.0% · · · · · $0 $0 $101M $0 $0 · $62M
Net Stock Activity 3-point trend, -100.0% · · · · · $0 $0 $101M · · · ·
Financing Cash Flow 9-point trend, -155.3% $-3M $-155.0K $0 $734.0K $4M $6M $6M $107M $5M · · ·
Net Change in Cash 12-point trend, -352.1% $-17M $-34M $792.0K $83M $-9M $16M $-16M $27M $-7M $-10M $-10M $-4M
Taxes Paid 5-point trend, -90000.00 $-90.0K $2M $4M $0 $0 · · · · · · ·
Free Cash Flow 11-point trend, -1213.1% $-110M $-16M $12M $31M $64M $50M $45M $30M $-4M $-10M $10M ·
Profitability 7
Annual Profitability data for VNDA
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, -91.3% -70.0% -20.5% -7.2% 2.5% 15.7% 11.0% 10.0% 11.3% -10.2% -12.7% -36.6% ·
Net Margin 11-point trend, -181.3% -102.0% -9.5% 1.3% 2.5% 12.3% 9.4% 50.9% 13.1% -9.4% -12.3% -36.3% ·
Pretax Margin 10-point trend, -423.3% -64.2% -11.5% 3.3% 4.4% 15.8% 12.8% 12.8% 13.1% -9.3% -12.3% · ·
EBITDA Margin 11-point trend, -91.3% -70.0% -20.5% -7.2% 2.5% 15.7% 11.0% 10.0% 11.3% -10.2% -12.7% -36.6% ·
ROA 11-point trend, -85.9% -38.5% -2.9% 0.39% 1.0% 5.9% 4.6% 28.3% 9.4% -7.5% -8.5% -20.7% ·
ROE 11-point trend, -99.8% -54.2% -3.5% 0.46% 1.2% 6.6% 5.2% 28.5% 9.4% -11.8% -13.6% -27.1% ·
ROIC 10-point trend, -416.7% -73.5% -6.2% -1.0% 0.67% 6.5% 4.4% 22.1% 7.9% -13.0% -14.2% · ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for VNDA
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -26.3% 2.4 4.4 4.9 5.7 6.4 6.2 6.0 5.6 2.4 3.5 3.2 ·
Quick Ratio 11-point trend, -26.6% 1.0 1.5 1.9 1.8 1.1 1.4 1.2 1.7 0.7 1.2 1.3 ·
Efficiency 3
Annual Efficiency data for VNDA
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, -34.0% 0.4 0.3 0.3 0.4 0.5 0.5 0.6 0.7 0.8 0.7 0.6 ·
Inventory Turnover · · · · · · · · · · 7.3 ·
Receivables Turnover 11-point trend, -61.4% 4.3 4.9 5.7 7.7 8.6 8.8 8.2 8.3 8.7 8.0 11.0 ·
Per Share 5
Annual Per Share data for VNDA
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, +78.2% $5.54 $9.24 $9.47 $9.28 $9.03 $8.26 $7.67 $5.25 $2.92 $2.98 $3.11 ·
Revenue / Share 11-point trend, +40.9% $3.67 $3.42 $3.35 $4.46 $4.72 $4.50 $4.14 $3.64 $3.69 $3.36 $2.60 ·
Cash Flow / Share 11-point trend, -730.4% $-1.86 $-0.27 $0.22 $0.56 $1.13 $0.94 $0.84 $0.57 $-0.04 $-0.19 $0.29 ·
Cash / Share 11-point trend, +20.9% $1.44 $1.75 $2.36 $2.38 $0.93 $1.11 $0.84 $1.16 $0.75 $0.92 $1.19 ·
EPS (TTM) 12-point trend, -780.0% $-3.74 $-0.33 $0.04 $0.11 $0.58 $0.42 $2.11 $0.48 $-0.35 $-0.41 $-0.94 $0.55
Growth Rates 7
Annual Growth Rates data for VNDA
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +5.4% 8.7% 3.2% -24.3% -5.3% 8.3% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +34.7% -5.3% -9.6% -8.1% · · · · · · · · ·
Revenue CAGR 5Y -2.7% · · · · · · · · · · ·
EPS YoY 3-point trend, -267.0% · · -63.6% -81.0% 38.1% · · · · · · ·
EPS CAGR 3Y · · -54.3% · · · · · · · · ·
Net Income YoY 3-point trend, -242.7% · · -60.0% -81.1% 42.1% · · · · · · ·
Net Income CAGR 3Y · · -52.4% · · · · · · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for VNDA
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +330.9% $216M $199M $193M $254M $269M $248M $227M $193M $165M $146M $110M $50M
Net Income TTM 12-point trend, -1192.2% $-220M $-19M $3M $6M $33M $23M $116M $25M $-16M $-18M $-40M $20M
Market Cap 11-point trend, +30.8% $521M $279M $243M $420M $877M $721M $879M $1.37B $683M $702M $399M ·
P/E 12-point trend, -109.1% -2.4 -14.5 105.5 67.2 27.1 31.3 7.8 54.4 -43.4 -38.9 -9.9 26.0
P/S 11-point trend, -33.5% 2.4 1.4 1.3 1.6 3.3 2.9 3.9 7.1 4.1 4.8 3.6 ·
P/B 11-point trend, -46.8% 1.6 0.5 0.4 0.8 1.7 1.6 2.1 5.0 5.2 5.3 3.0 ·
P / Tangible Book 6-point trend, +48.6% 2.5 0.7 0.6 0.8 1.8 1.7 · · · · · ·
P / Cash Flow 11-point trend, -114.9% -4.8 -17.7 19.0 13.1 13.7 13.9 19.1 45.7 -344.5 -86.6 32.0 ·
P / FCF 11-point trend, -111.7% -4.7 -17.2 19.6 13.4 13.8 14.4 19.6 46.3 -187.3 -73.8 40.2 ·
Earnings Yield 12-point trend, -1204.2% -42.4% -6.9% 0.95% 1.5% 3.7% 3.2% 12.9% 1.8% -2.3% -2.6% -10.1% 3.8%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $216M$199M$193M$254M$269M
Operating Margin % -70.0%-20.5%-7.2%2.5%15.7%
Net Income $-220M$-19M$3M$6M$33M
Diluted EPS $-3.74$-0.33$0.04$0.11$0.58
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 2.44.44.95.76.4
Quick Ratio 1.01.51.91.81.1
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-110M$-16M$12M$31M$64M

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Institutional owners (13F) 185 filers · $213.7M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
34 (-12 vs prior Q) 24 (-6 vs prior Q) 57 (-2 vs prior Q) 57 (+17 vs prior Q) +3.7M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
VANGUARD GROUP INC $28,922,050 3,279,144 13.53% Shares
STATE STREET CORP $21,520,399 3,516,405 10.07% Shares
RENAISSANCE TECHNOLOGIES LLC $21,061,129 3,441,361 9.85% Shares
VANGUARD CAPITAL MANAGEMENT LLC $15,447,125 2,524,040 7.23% Shares
DIMENSIONAL FUND ADVISORS LP $10,108,839 1,651,771 4.73% Shares
MILLENNIUM MANAGEMENT LLC $9,809,216 1,602,813 4.59% Shares
TWO SIGMA ADVISERS, LP $9,254,826 1,049,300 4.33% Shares
TWO SIGMA INVESTMENTS, LP $8,256,321 1,349,072 3.86% Shares
GEODE CAPITAL MANAGEMENT, LLC $7,778,105 1,270,570 3.64% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $7,425,555 1,213,326 3.47% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $6,921,928 1,131,034 3.24% Shares
GOLDMAN SACHS GROUP INC $4,472,692 730,832 2.09% Shares
Qube Research & Technologies Ltd $4,462,777 729,212 2.09% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $3,955,087 646,256 1.85% Shares
BlackRock, Inc. $3,085,673 504,195 1.44% Shares
AIGH Capital Management LLC $3,060,692 500,113 1.43% Shares
VANGUARD FIDUCIARY TRUST CO $2,446,880 399,817 1.14% Shares
Quantinno Capital Management LP $1,920,383 313,788 0.90% Shares
Point72 Asset Management, L.P. $1,905,535 311,362 0.89% Shares
LOS ANGELES CAPITAL MANAGEMENT LLC $1,854,978 303,101 0.87% Shares
Y-Intercept (Hong Kong) Ltd $1,800,082 294,131 0.84% Shares
IEQ CAPITAL, LLC $1,730,607 282,779 0.81% Shares
Susquehanna Portfolio Strategies, LLC $1,451,566 237,184 0.68% Shares
KENNEDY CAPITAL MANAGEMENT LLC $1,436,933 234,793 0.67% Shares
CITADEL ADVISORS LLC $1,422,949 232,508 0.67% Shares
Monaco Asset Management SAM $1,354,270 221,286 0.63% Shares
AMERIPRISE FINANCIAL INC $1,326,865 216,808 0.62% Shares
Connor, Clark & Lunn Investment Management Ltd. $1,317,061 215,206 0.62% Shares
Mariner, LLC $1,061,705 173,480 0.50% Shares
AMERICAN CENTURY COMPANIES INC $970,638 158,601 0.45% Shares
BANK OF AMERICA CORP /DE/ $968,809 158,302 0.45% Shares
Man Group plc $939,769 153,557 0.44% Shares
KOTLER KEVIN $882,000 100,000 0.41% Shares
KLP KAPITALFORVALTNING AS $828,648 135,400 0.39% Shares
MERCER GLOBAL ADVISORS INC /ADV $749,982 122,546 0.35% Shares
Jefferies Financial Group Inc. $749,253 122,427 0.35% Shares
Trexquant Investment LP $741,077 121,091 0.35% Shares
MARSHALL WACE, LLP $723,910 118,286 0.34% Shares
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO $622,098 101,650 0.29% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $587,520 96,000 0.27% Call option
HSBC HOLDINGS PLC $579,427 94,988 0.27% Shares
Corient Private Wealth LP $578,029 94,449 0.27% Shares
FRANKLIN RESOURCES INC $557,960 91,170 0.26% Shares
CWM, LLC $534,599 77,366 0.25% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $525,181 97,400 0.25% Shares
FMR LLC $524,466 85,697 0.25% Shares
STRS OHIO $520,812 85,100 0.24% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $502,122 82,046 0.23% Shares
ALLIANCEBERNSTEIN L.P. $495,675 71,733 0.23% Shares
BARCLAYS PLC $486,480 79,490 0.23% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $472,635 77,228 0.22% Shares
Creative Planning $444,661 72,657 0.21% Shares
RHUMBLINE ADVISERS $440,476 71,975 0.21% Shares
CITADEL ADVISORS LLC $436,968 71,400 0.20% Call option
Bank of New York Mellon Corp $412,549 67,410 0.19% Shares
Balyasny Asset Management L.P. $397,353 64,927 0.19% Shares
Inscription Capital, LLC $390,933 63,878 0.18% Shares
Rafferty Asset Management, LLC $389,862 63,703 0.18% Shares
PANAGORA ASSET MANAGEMENT INC $363,093 59,329 0.17% Shares
Brandywine Global Investment Management, LLC $347,420 39,390 0.16% Shares
FEDERATED HERMES, INC. $339,837 55,529 0.16% Shares
DEUTSCHE BANK AG\ $321,582 52,546 0.15% Shares
MARTINGALE ASSET MANAGEMENT L P $320,340 52,343 0.15% Shares
Cubist Systematic Strategies, LLC $318,467 63,821 0.15% Shares
FULLER & THALER ASSET MANAGEMENT, INC. $302,083 49,360 0.14% Shares
WELLS FARGO & COMPANY/MN $276,006 45,099 0.13% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $239,292 39,100 0.11% Put option
Arax Advisory Partners $222,873 36,417 0.10% Shares
CAPTRUST FINANCIAL ADVISORS $222,621 36,376 0.10% Shares
Engineers Gate Manager LP $210,999 34,477 0.10% Shares
WINTON GROUP Ltd $206,856 33,800 0.10% Shares
JPMORGAN CHASE & CO $205,997 33,550 0.10% Shares
XTX Topco Ltd $203,619 33,271 0.10% Shares
PROFUND ADVISORS LLC $196,470 32,103 0.09% Shares
Focus Partners Wealth $188,368 30,779 0.09% Shares
MetLife Investment Management, LLC $187,046 30,563 0.09% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $178,588 29,181 0.08% Shares
Grantham, Mayo, Van Otterloo & Co. LLC $173,465 28,344 0.08% Shares
UBS Group AG $165,687 27,073 0.08% Shares
ExodusPoint Capital Management, LP $163,018 26,637 0.08% Shares
BRIGHTON JONES LLC $159,641 26,085 0.07% Shares
Jain Global LLC $154,224 25,200 0.07% Shares
Nuveen Asset Management, LLC $150,382 31,395 0.07% Shares
Vanguard Global Advisers, LLC $149,316 24,398 0.07% Shares
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $141,372 23,100 0.07% Shares
HORIZON KINETICS ASSET MANAGEMENT LLC $138,606 22,648 0.06% Shares
DIKER MANAGEMENT LLC $134,000 21,880 0.06% Shares
Cerity Partners LLC $133,385 21,795 0.06% Shares
Invesco Ltd. $131,415 21,473 0.06% Shares
Merit Financial Group, LLC $129,120 21,098 0.06% Shares
CITADEL ADVISORS LLC $126,684 20,700 0.06% Put option
SYON CAPITAL LLC $124,854 20,401 0.06% Shares
CANADA PENSION PLAN INVESTMENT BOARD $123,012 20,100 0.06% Shares
Pallas Capital Advisors LLC $113,863 18,605 0.05% Shares
Optiver Holding B.V. $110,705 18,089 0.05% Shares
PRUDENTIAL FINANCIAL INC $107,363 17,543 0.05% Shares
Entropy Technologies, LP $104,572 17,087 0.05% Shares
BNP PARIBAS FINANCIAL MARKETS $104,217 17,029 0.05% Shares
Krilogy Financial LLC $99,805 16,308 0.05% Shares
LPL Financial LLC $96,727 15,805 0.05% Shares

Company insiders 45 insiders · 18 officers · 16 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Kevin Patrick Moran SVP, CFO & Treasurer Feb. 18, 2026 A 453,822 0 0 $0
James Patrick Kelly EVP & Chief Financial Officer March 3, 2020 S 186,869 0 0 $0
Stephanie Rast Irish Acting CFO/Treasurer Feb. 19, 2010 S 2,249 0 0 $0
Steven A Shallcross Sr. VP, CFO, Treasurer Jan. 4, 2008 A 0 0 0 $0
McGuire Daniel Patrick SVP, GC and Secretary June 4, 2026 A 109,982 0 0 $0
Joakim Wijkstrom SVP, Chief Marketing Officer Feb. 18, 2026 A 364,269 0 0 $0
Timothy Williams SVP & General Counsel Feb. 18, 2026 A 419,884 0 0 $0
Gunther Birznieks SVP, Business Development Feb. 18, 2026 A 536,628 0 0 $0
Aranthan Jones II Chief Corp. Affairs Officer Sept. 15, 2021 M 81,980 0 0 $0
Gian Piero Reverberi SVP & Chief Commercial Officer March 2, 2020 S 165,384 0 0 $0
Richard L. Gulino SVP, General Counsel & Sec. Feb. 28, 2018 A 115,073 0 0 $0
Paolo Baroldi SVP & Chief Medical Officer Jan. 3, 2017 M 54,365 0 0 $0
Thomas Edward Gibbs SVP, Chief Commercial Officer April 20, 2015 A 0 0 $0
Robert Repella SVP & Chief Commercial Officer Nov. 21, 2013 M 15,000 0 0 $0
John Joseph Feeney SVP & Chief Medical Officer Feb. 16, 2012 S 11,942 0 0 $0
William D Clark Sr. VP, Chief Business Officer Feb. 19, 2010 S 168,279 0 0 $0
Albert W. Gianchetti Sr.VP,Chief Commercial Officer Jan. 4, 2008 A 3,000 0 0 $0
Deepak Shripad Phadke Vice President Manufacturing Dec. 12, 2006 M 0 0 0 $0
Charles Cliff Duncan Director June 4, 2026 A 98,701 0 0 $0
Tage Honore Director June 4, 2026 A 135,069 0 1 $-240,900
Stephen Ray Mitchell Director June 4, 2026 A 112,846 0 0 $0
Anne Sempowski Ward Director June 4, 2026 A 160,667 0 0 $0
Phaedra Chrousos Director June 4, 2026 A 164,950 0 0 $0
Richard W Dugan Director June 4, 2026 A 219,054 0 0 $0
Thomas Watkins Director June 2, 2022 M 63,064 0 0 $0
Michael F Cola Director June 13, 2019 A 15,000 0 0 $0
Vincent Milano Director June 13, 2018 A 10,000 0 0 $0
Kenneth Bate Director June 15, 2017 A 5,000 0 0 $0
Howard H Pien Director June 18, 2015 A 0 0 $0
Steven K Galson Director May 22, 2014 A 0 0 $0
Argeris N Karabelas Director June 16, 2011 A 0 0 0 $0
Brian K Halak Director March 26, 2010 J 7,276 0 0 $0
James B Tananbaum Director May 16, 2007 A 11,041 0 0 $0
Wayne T Hockmeyer Director April 18, 2006 C 1,601,798 0 0 $0
DP VI Associates, L.P. 10% owner Dec. 12, 2006 S 21,068 0 0 $0
Domain Partners VI, L.P. 10% owner Dec. 12, 2006 J 1,954,450 0 0 $0
Robert J More 10% owner Dec. 12, 2006 S 21,068 0 0 $0
Kathleen K Schoemaker 10% owner Dec. 12, 2006 S 21,068 0 0 $0
Brian H Dovey 10% owner Dec. 12, 2006 S 21,068 0 0 $0
Nicole Vitullo 10% owner Dec. 12, 2006 S 21,068 0 0 $0
BLAIR JAMES C 10% owner Dec. 12, 2006 S 21,068 0 0 $0
TREU JESSE I 10% owner Dec. 12, 2006 S 21,068 0 0 $0
MEDIMMUNE INC /DE 10% owner April 18, 2006 C 1,601,798 0 0 $0
Mihael Hristos Polymeropoulos March 2, 2026 S 2,704,496 0 1 $-1,276,440
David Russ Ramsay March 12, 2010 S 0 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 2 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Tang Capital Partners, LP, Tang Capital Management, LLC, Kevin C. Tang ×3 filings Feb. 18, 2009 Initial filing SEC
Care Capital, LLC, Care Capital II, LLC, Care Capital Offshore Investments II, LP, Care Capital Investments II, LP, Jan Leschly, David Ramsay, Argeris Karabelas Feb. 13, 2007 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 43 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
QQQS · Invesco Exchange-Traded Fund Trust … 0.38% 17,337 SH Aug. 8, 2026 Daily
IBRN · iShares Trust 0.30% 4,456 SH Aug. 8, 2026 Daily
SBIO · ALPS ETF Trust 0.24% 60,925 NS May 31, 2026 N-PORT
HAPS · Harbor ETF Trust 0.24% 52,295 NS April 30, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.14% 99,351 NS April 30, 2026 N-PORT
FSCC · Federated Hermes ETF Trust 0.12% 52,235 NS May 31, 2026 N-PORT
VFMF · VANGUARD WELLINGTON FUND 0.09% 101,215 SH Aug. 8, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.08% 256,365 SH Aug. 8, 2026 Daily
IWC · iShares Trust 0.06% 183,719 SH Aug. 8, 2026 Daily
JPSE · J.P. Morgan Exchange-Traded Fund Tr… 0.04% 33,401 NS April 30, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.03% 135,610 NS May 31, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.03% 42,387 NS May 31, 2026 N-PORT
IBB · iShares Trust 0.02% 415,984 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.02% 3,243 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.02% 46,913 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 111,691 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.02% 2,186 NS May 31, 2026 N-PORT
IWN · iShares Trust 0.02% 511,376 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.01% 24,139 NS April 30, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 309,952 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.01% 194,530 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.01% 2,623 NS May 31, 2026 N-PORT
IWM · iShares Trust 0.01% 1,375,350 SH Aug. 8, 2026 Daily
SCHA · SCHWAB STRATEGIC TRUST 0.01% 286,177 NS May 31, 2026 N-PORT
DFSV · Dimensional ETF Trust 0.01% 68,013 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.01% 2,050 NS May 31, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.01% 2,824 NS April 30, 2026 N-PORT
URTY · ProShares Trust 0.00% 2,076 NS May 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 160,380 NS April 30, 2026 N-PORT
AVSU · AMERICAN CENTURY ETF TRUST 0.00% 1,556 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 2,091 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 52 NS May 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 6,317 NS April 30, 2026 N-PORT
ITOT · iShares Trust 0.00% 118,725 SH Aug. 8, 2026 Daily
DFAU · Dimensional ETF Trust 0.00% 10,453 NS April 30, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 40,824 NS May 31, 2026 N-PORT
AVUS · AMERICAN CENTURY ETF TRUST 0.00% 11,217 NS May 31, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 12,885 NS April 30, 2026 N-PORT
IWV · iShares Trust 0.00% 15,111 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 703,477 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 1,761,840 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 5,171 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.00% 155,868 SH Aug. 8, 2026 Daily