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ANNX Annexon, Inc. - common stock
NASDAQ · Biotechnology · Ver en SEC EDGAR ↗ cerrar Oct 2, 2026 10-K/10-Q Ago 12, 2026
$4,19
· % del rango de 52 semanas
· por encima del mínimo
· a alto
$2,54mínimo 52 semanas
$7,18máximo 52 semanas
Capitalización Bursátil
$626M
P/E
-3.1
BPA
$-1.34
tus insignias
Rango 52S
$3–$7
Calificación del Analista
BUY
Precio Objetivo
$15
P/E
-3.1
ROE
-100.7%
Margen de Beneficio Neto
·
Tu barra de insignias está vacía — fija una métrica en cualquier lugar de esta página.
ANNX Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$4.19
Capitalización Bursátil
$626M
P/E
-3.1
BPA
$-1.34
ROE
-100.7%
Rango 52S
$3–$7
ANNX Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
rango
barras
La granularidad de las barras se adapta al período seleccionado; pase el ratón sobre el gráfico para ver la apertura/máximo/mínimo/cierre de una barra.
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
BPA$-1.342021-12-31 → 2025-12-31
Flujo de caja libre$-186M2020-12-31 → 2025-12-31
Valoración y ratios
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
| Métrica | Tendencia a 5 años | ANNX | promedio 5A | Mediana de Pares | Veredicto |
|---|---|---|---|---|---|
| P/E | -3.1promedio 5A ≈-3.4 | ≈-3.4 | · | · | |
| P/B (P/C) | 3.0promedio 5A ≈2.0 | ≈2.0 | 3.3 | Valor razonable | |
| Price / FCF (Precio / FCF) | -3.4promedio 5A ≈-3.6 | ≈-3.6 | · | · | |
| Price / Cash Flow (Precio / Flujo de Caja) | -3.4promedio 5A ≈-3.6 | ≈-3.6 | · | · | |
| Price / Tangible Book (Precio / Valor Contable Tangible) | 3.0promedio 5A ≈2.0 | ≈2.0 | · | · |
La mediana de empresas comparables se calcula sobre una base estandarizada por métrica y puede no coincidir siempre con la base TTM/MRQ que se muestra para esta acción.
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
| Métrica | Tendencia a 5 años | ANNX | promedio 5A | Mediana de Pares | Veredicto |
|---|---|---|---|---|---|
| ROA | -65.9%promedio 5A ≈-49.0% | ≈-49.0% | -45.7% | Débil | |
| ROE | -100.7%promedio 5A ≈-64.2% | ≈-64.2% | -51.4% | Débil | |
| ROIC | -102.2%promedio 5A ≈-70.7% | ≈-70.7% | -47.7% | Débil |
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
| Métrica | Tendencia a 5 años | ANNX | promedio 5A | Mediana de Pares | Veredicto |
|---|---|---|---|---|---|
| Ratio corriente (MRQ) | 5.5promedio 5A ≈10.7 | ≈10.7 | 6.1 | Baja liquidez | |
| Quick Ratio (Ratio Rápido) | 3.8promedio 5A ≈5.5 | ≈5.5 | 4.6 | En línea |
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Aún no hay datos para este grupo de ratios
Aún no hay datos fundamentales para este ticker.
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Aún no hay datos para este grupo de ratios
Aún no hay datos fundamentales para este ticker.
valor · ≈ promedio 5A · mediana sectorial · veredicto relativo a la mediana
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
-3.0%
Próximo informe
Nov 09, 2026
| Período | Informe | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|---|
| 30 de junio de 2026 | Ago 17, 2026 | $-0.28 | $-0.24 | -14.8% |
| 31 de marzo de 2026 | May 18, 2026 | $-0.23 | $-0.29 | 22.0% |
| 31 de diciembre de 2025 | $-0.28 | $-0.32 | 12.2% | |
| 30 de septiembre de 2025 | $-0.37 | $-0.35 | -6.7% | |
| 30 de junio de 2025 | $-0.34 | $-0.37 | 8.8% | |
| 31 de marzo de 2025 | $-0.37 | $-0.30 | -22.4% | |
| 31 de diciembre de 2024 | $-0.33 | $-0.27 | -20.2% |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $185M | $119M | $114M | $113M | $100M | $49M | $25M | |
| SG&A Expense | $32M | $35M | $30M | $33M | $31M | $14M | $8M | |
| Operating Expenses | $216M | $154M | $144M | $146M | $131M | $63M | $33M | |
| Operating Income | $-216M | $-154M | $-144M | $-146M | $-131M | $-63M | $-33M | |
| Other Non-op | · | · | · | · | · | $57.0K | $1M | |
| Pretax Income | $-207M | $-138M | $134M | $142M | $130M | $-63M | $-37M | |
| Income Tax | $0 | $0 | $0 | $0 | · | · | $4.0K | |
| Net Income | $-207M | $-138M | $-134M | $-142M | $-130M | $-63M | $-37M | |
| EPS (Basic) | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 | · | · | |
| EPS (Diluted) | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 | · | · | |
| Shares (Basic) | 155,105,832 | 137,404,145 | 75,673,081 | 54,673,572 | 38,316,273 | · | · | |
| Shares (Diluted) | 155,105,832 | 137,404,145 | 75,673,081 | 54,673,572 | 38,316,273 | · | · | |
| EBITDA | $-214M | $-152M | $-142M | $-143M | $-129M | $-63M | · |
Balance general
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $162M | $49M | $225M | $140M | $75M | $269M | $44M | |
| Prepaid Expense | $4M | $4M | $4M | $5M | $5M | $3M | $1M | |
| Other Current Assets | · | · | $63.0K | $203.0K | $463.0K | $3.0K | $79.0K | |
| Current Assets | $242M | $316M | $264M | $248M | $248M | $354M | $45M | |
| PP&E (Net) | $11M | $13M | $15M | $17M | $18M | $2M | $2M | |
| PP&E (Gross) | $20M | $20M | $20M | $20M | $19M | $4M | $3M | |
| Accum. Depreciation | $9M | $7M | $5M | $3M | $789.0K | $2M | $1M | |
| Other Non-current Assets | $9M | $3M | · | · | · | · | $2M | |
| Total Assets | $278M | $350M | $298M | $285M | $287M | $356M | $50M | |
| Accounts Payable | $15M | $10M | $5M | $7M | $11M | $4M | $2M | |
| Accrued Liabilities | · | · | $10M | $13M | $9M | $6M | $2M | |
| Current Liabilities | $43M | $31M | $18M | $22M | $22M | $11M | $5M | |
| Capital Leases | $23M | $26M | $29M | $32M | $33M | · | · | |
| Total Liabilities | $66M | $57M | $47M | $54M | $55M | $12M | $6M | |
| Common Stock | $149.0K | $109.0K | $78.0K | $48.0K | $39.0K | $38.0K | $4.0K | |
| Paid-in Capital | $1.13B | $1.00B | $823M | $670M | $528M | $510M | $2M | |
| Retained Earnings | $-917M | $-711M | $-572M | $-438M | $-296M | $-166M | $-103M | |
| AOCI | $-29.0K | $10.0K | $-52.0K | $-372.0K | $-180.0K | $-77.0K | $-80.0K | |
| Stockholders' Equity | $212M | $293M | $251M | $231M | $232M | $344M | $-100M | |
| Liabilities + Equity | $278M | $350M | $298M | $285M | $287M | $356M | $50M | |
| Shares Outstanding | 149,362,800 | 109,381,556 | 78,369,099 | 47,722,995 | 38,560,854 | 38,157,618 | 433,749 |
Flujo de Efectivo
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $2M | $2M | $667.0K | $493.0K | |
| Stock-based Comp | $16M | $19M | $18M | $19M | $16M | $5M | $2M | |
| Other Non-cash | $2M | $-1M | $-7M | $5M | $6M | $5M | · | |
| Operating Cash Flow | $-186M | $-118M | $-121M | $-116M | $-106M | $-53M | $-28M | |
| CapEx | $137.0K | $15.0K | $193.0K | $7M | $2M | $464.0K | $267.0K | |
| Investing Cash Flow | $190M | $-219M | $71M | $58M | $-88M | $-83M | $-267.0K | |
| Stock Issued | $28M | $44M | $18M | · | · | · | · | |
| Net Stock Activity | $28M | $44M | · | · | · | · | · | |
| Financing Cash Flow | $109M | $161M | $136M | $123M | $2M | $361M | $28M | |
| Free Cash Flow | $-186M | $-118M | $-121M | $-123M | $-108M | $-54M | · |
Rentabilidad
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -65.9% | -42.7% | -46.1% | -49.6% | -40.5% | -31.2% | · | |
| ROE | -100.7% | -44.2% | -65.9% | -57.7% | -52.5% | -17.9% | · | |
| ROIC | -102.2% | -52.6% | -57.4% | · | · | · | · |
Liquidez y Solvencia
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.7 | 10.4 | 14.7 | 11.1 | 11.4 | 33.3 | · | |
| Quick Ratio | 3.8 | 1.6 | 12.6 | 6.3 | 3.4 | 25.3 | · |
Por Acción
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $1.42 | $2.68 | $3.20 | $4.84 | $6.01 | $9.02 | · | |
| Cash Flow / Share | $-1.20 | $-0.86 | $-1.60 | $-2.13 | · | · | · | |
| Cash / Share | $1.08 | $0.45 | $2.87 | $2.93 | $1.94 | $7.04 | · | |
| Dividend / Share | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | · | |
| EPS (TTM) | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 | · | · |
Valoración (TTM)
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-207M | $-138M | $-134M | $-142M | $-130M | $-63M | · | |
| Market Cap | $750M | $561M | $356M | $247M | $443M | $955M | · | |
| P/E | -3.7 | -5.1 | -2.6 | -2.0 | -3.4 | · | · | |
| P/B | 3.5 | 1.9 | 1.4 | 1.1 | 1.9 | 2.8 | · | |
| P / Tangible Book | 3.5 | 1.9 | 1.4 | 1.1 | 1.9 | 2.8 | · | |
| P / Cash Flow | -4.0 | -4.8 | -2.9 | -2.1 | -4.2 | -18.0 | · | |
| P / FCF | -4.0 | -4.8 | -2.9 | -2.0 | -4.1 | -17.8 | · | |
| Earnings Yield | -26.7% | -19.7% | -39.0% | -50.3% | -29.6% | · | · |
Estado de resultados
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $47M | $36M | $43M | $50M | $44M | $48M | $43M | $30M | $25M | $21M | $23M | $28M | $30M | $32M | $29M | $28M | |
| SG&A Expense | $11M | $10M | $8M | $7M | $8M | $9M | $9M | $9M | $9M | $8M | $7M | $7M | $7M | $9M | $8M | $8M | |
| Operating Expenses | $57M | $46M | $50M | $57M | $52M | $57M | $52M | $39M | $34M | $29M | $30M | $35M | $38M | $41M | $37M | $36M | |
| Operating Income | $-57M | $-46M | $-50M | $-57M | $-52M | $-57M | $-52M | $-39M | $-34M | $-29M | $-30M | $-35M | $-38M | $-41M | $-37M | $-36M | |
| Net Income | $-55M | $-44M | $-48M | $-55M | $-49M | $-54M | $-49M | $-35M | $-30M | $-25M | $-28M | $-32M | $-35M | $-39M | $-34M | $-35M | |
| EPS (Basic) | $-0.28 | $-0.23 | $-0.26 | $-0.37 | $-0.34 | $-0.37 | $-0.32 | $-0.25 | $-0.23 | $-0.21 | $-0.35 | $-0.43 | $-0.47 | $-0.52 | $-0.21 | $-0.51 | |
| EPS (Diluted) | $-0.28 | $-0.23 | $-0.26 | $-0.37 | $-0.34 | $-0.37 | $-0.32 | $-0.25 | $-0.23 | $-0.21 | $-0.35 | $-0.43 | $-0.47 | $-0.52 | $-0.21 | $-0.51 | |
| Shares (Basic) | 201,003,269 | 194,200,100 | · | 149,123,701 | 148,320,803 | 148,108,809 | · | 139,933,019 | 130,132,960 | 122,673,202 | · | 75,342,495 | 75,230,003 | 73,855,642 | · | 68,652,859 | |
| Shares (Diluted) | 201,003,269 | 194,200,100 | · | 149,123,701 | 148,320,803 | 148,108,809 | · | 139,933,019 | 130,132,960 | 122,673,202 | · | 75,342,495 | 75,230,003 | 73,855,642 | · | 68,652,859 | |
| EBITDA | $-57M | $-46M | · | $-57M | $-52M | $-57M | · | $-39M | $-34M | $-28M | · | $-35M | $-38M | $-41M | · | $-36M |
Balance general
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $199M | $175M | $162M | $139M | $132M | $97M | $49M | $80M | $157M | $152M | $225M | $133M | $114M | $144M | $140M | $211M | |
| Prepaid Expense | $4M | $3M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $6M | $4M | $4M | $5M | $4M | $5M | $5M | |
| Other Current Assets | · | · | · | · | · | · | · | · | · | $23.0K | · | $13.0K | $167.0K | $165.0K | $203.0K | $57.0K | |
| Current Assets | $213M | $228M | $242M | $193M | $231M | $268M | $316M | $344M | $374M | $271M | $264M | $169M | $198M | $233M | $248M | $275M | |
| PP&E (Net) | $10M | $10M | $11M | $11M | $12M | $12M | $13M | $13M | $14M | $14M | $15M | $15M | $16M | $16M | $17M | $17M | |
| PP&E (Gross) | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $19M | |
| Accum. Depreciation | $10M | $10M | $9M | $9M | $8M | $8M | $7M | $7M | $6M | $6M | $5M | $4M | $4M | $3M | $3M | $2M | |
| Other Non-current Assets | $8M | $9M | $9M | $9M | $5M | $5M | $3M | $3M | · | $361.0K | · | · | · | $12.0K | · | $204.0K | |
| Total Assets | $246M | $263M | $278M | $229M | $265M | $303M | $350M | $379M | $406M | $304M | $298M | $204M | $233M | $269M | $285M | $313M | |
| Accounts Payable | $16M | $18M | $15M | $18M | $12M | $10M | $10M | $7M | $4M | $4M | $5M | $5M | $7M | $10M | $7M | $7M | |
| Accrued Liabilities | · | · | · | · | · | · | · | · | $11M | $7M | · | $10M | $9M | $11M | $13M | $11M | |
| Current Liabilities | $38M | $36M | $43M | $44M | $41M | $34M | $31M | $20M | $17M | $13M | $18M | $17M | $18M | $23M | $22M | $20M | |
| Capital Leases | $22M | $22M | $23M | $24M | $25M | $26M | $26M | $27M | $28M | $29M | $29M | $30M | $30M | $31M | $32M | $32M | |
| Total Liabilities | $60M | $58M | $66M | $68M | $66M | $59M | $57M | $47M | $45M | $42M | $47M | $47M | $48M | $54M | $54M | $52M | |
| Common Stock | $175.0K | $162.0K | $149.0K | $115.0K | $110.0K | $109.0K | $109.0K | $106.0K | $106.0K | $90.0K | $78.0K | $53.0K | $53.0K | $53.0K | $48.0K | $48.0K | |
| Paid-in Capital | $1.20B | $1.17B | $1.13B | $1.03B | $1.01B | $1.01B | $1.00B | $993M | $988M | $860M | $823M | $702M | $697M | $692M | $670M | $665M | |
| Retained Earnings | $-1.02B | $-962M | $-917M | $-869M | $-814M | $-765M | $-711M | $-662M | $-627M | $-598M | $-572M | $-545M | $-512M | $-477M | $-438M | $-404M | |
| AOCI | $-82.0K | $-81.0K | $-29.0K | $-76.0K | $-93.0K | $-91.0K | $10.0K | $77.0K | $-89.0K | $-102.0K | $-52.0K | $-123.0K | $-171.0K | $-217.0K | $-372.0K | $-406.0K | |
| Stockholders' Equity | $186M | $205M | $212M | $161M | $199M | $244M | $293M | $332M | $361M | $262M | $251M | $157M | $185M | $215M | $231M | $261M | |
| Liabilities + Equity | $246M | $263M | $278M | $229M | $265M | $303M | $350M | $379M | $406M | $304M | $298M | $204M | $233M | $269M | $285M | $313M | |
| Shares Outstanding | · | · | 149,362,800 | · | · | · | 109,381,556 | · | · | · | 78,369,099 | · | · | · | 47,722,995 | · |
Flujo de Efectivo
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $540.0K | $539.0K | $543.0K | $546.0K | $540.0K | $537.0K | $537.0K | $538.0K | $537.0K | $538.0K | $538.0K | $538.0K | $536.0K | $536.0K | $530.0K | $518.0K | |
| Stock-based Comp | $5M | $4M | $3M | $4M | $4M | $5M | $5M | $5M | $5M | $5M | $4M | $5M | $5M | $5M | $5M | $5M | |
| Other Non-cash | · | $-7M | · | · | · | $-1M | · | · | · | $-8M | · | · | · | $540.0K | · | · | |
| Operating Cash Flow | $-48M | $-47M | $-46M | $-52M | $-38M | $-50M | $-36M | $-32M | $-22M | $-28M | $-23M | $-28M | $-36M | $-33M | $-27M | $-31M | |
| CapEx | $137.0K | $0 | $0 | $48.0K | $15.0K | $74.0K | $6.0K | · | · | · | $7.0K | $19.0K | $30.0K | $137.0K | $282.0K | $169.0K | |
| Investing Cash Flow | $40M | $27M | $-27M | $46M | $73M | $98M | $1M | $-46M | $-97M | $-77M | $-2M | $48M | $6M | $20M | $-44M | $14M | |
| Stock Issued | $32M | $34M | $14M | $14M | $0 | $0 | $5M | $0 | $7M | $33M | $0 | $450.0K | $450.0K | $18M | · | · | |
| Net Stock Activity | · | $34M | · | · | · | · | · | · | · | $33M | · | · | · | $18M | · | · | |
| Financing Cash Flow | $32M | $33M | $95M | $14M | $153.0K | $59.0K | $5M | $175.0K | $124M | $32M | $118M | $0 | $345.0K | $18M | $108.0K | $123M | |
| Free Cash Flow | · | $-47M | · | · | · | $-50M | · | · | · | · | · | · | · | $-33M | · | · |
Rentabilidad
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -21.7% | -15.6% | · | -18.1% | -14.7% | -17.9% | · | -11.9% | -9.3% | -9.1% | · | -13.8% | -15.5% | · | · | -11.3% | |
| ROE | -28.7% | -19.7% | · | -22.3% | -17.5% | -21.5% | · | -14.3% | -10.8% | -10.9% | · | -17.5% | -20.0% | · | · | -13.4% |
Liquidez y Solvencia
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.5 | 6.4 | · | 4.4 | 5.7 | 8.0 | · | 17.2 | 21.8 | 20.6 | · | 9.9 | 11.0 | · | · | 13.6 | |
| Quick Ratio | 5.2 | 4.9 | · | 3.2 | 3.3 | 2.9 | · | 4.0 | 9.2 | 11.6 | · | 7.8 | 6.4 | · | · | 10.4 |
Por Acción
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash Flow / Share | · | $-0.24 | · | · | · | $-0.34 | · | · | · | $-0.23 | · | · | · | $-0.45 | · | · | |
| EPS (TTM) | $-1.14 | $-1.20 | · | $-1.40 | $-1.28 | $-1.17 | · | $-1.04 | $-1.22 | $-1.46 | · | $-1.63 | $-1.71 | $-2.20 | · | $-3.36 |
Valoración (TTM)
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-203M | $-196M | · | $-207M | $-187M | $-167M | · | $-118M | $-115M | $-121M | · | $-141M | $-143M | $-145M | · | $-145M | |
| P/E | -5.0 | -4.6 | · | -2.2 | -1.9 | -1.6 | · | -5.7 | -4.0 | -4.9 | · | -1.4 | -2.1 | -1.8 | · | -1.8 | |
| Earnings Yield | -20.0% | -21.7% | · | -45.9% | -53.3% | -60.6% | · | -17.6% | -24.9% | -20.4% | · | -69.1% | -48.6% | -57.1% | · | -54.4% |
Período más reciente a la izquierda · valores nulos mostrados como ·
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
| Métrica | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Beneficio neto | $-207M | $-138M | $-134M | $-142M | $-130M |
| EPS Diluido | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 |
| Métrica | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Ratio corriente | 5.7 | 10.4 | 14.7 | 11.1 | 11.4 |
| Ratio Rápido | 3.8 | 1.6 | 12.6 | 6.3 | 3.4 |
| Métrica | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Flujo de caja libre | $-186M | $-118M | $-121M | $-123M | $-108M |
Propietarios institucionales (13F) 230 declarantes · $1.1B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Tenedores
230
Valor en tenencia
$1.1B
Nuevas posiciones
34
Posiciones cerradas
27
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 34 (-34 vs trimestre anterior) | 27 (+12 vs trimestre anterior) | 81 (-9 vs trimestre anterior) | 78 (+30 vs trimestre anterior) | +26.8M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| FMR LLC | $111 450 614 | 19 518 496 | 10,53% | Acciones |
| BlackRock, Inc. | $77 311 938 | 13 539 744 | 7,31% | Acciones |
| Redmile Group, LLC | $67 776 998 | 11 869 877 | 6,41% | Acciones |
| STATE STREET CORP | $56 096 873 | 9 824 321 | 5,30% | Acciones |
| BVF INC/IL | $49 666 568 | 8 698 173 | 4,69% | Acciones |
| Woodline Partners LP | $39 542 133 | 6 925 067 | 3,74% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $39 233 496 | 6 871 015 | 3,71% | Acciones |
| VANGUARD GROUP INC | $38 922 003 | 7 753 387 | 3,68% | Acciones |
| MAK CAPITAL ONE LLC | $33 473 048 | 5 862 180 | 3,16% | Acciones |
| GOLDMAN SACHS GROUP INC | $33 264 057 | 5 825 579 | 3,14% | Acciones |
| Siren, L.L.C. | $25 458 869 | 4 458 646 | 2,41% | Acciones |
| Bain Capital Life Sciences Investors, LLC | $25 339 444 | 4 437 731 | 2,39% | Acciones |
| Bellevue Group AG | $23 411 091 | 4 100 016 | 2,21% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $23 056 071 | 4 037 193 | 2,18% | Acciones |
| MPM BIOIMPACT LLC | $20 238 261 | 3 544 354 | 1,91% | Acciones |
| AMERIPRISE FINANCIAL INC | $20 039 948 | 3 509 623 | 1,89% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $19 985 000 | 3 500 000 | 1,89% | Acciones |
| GREAT POINT PARTNERS LLC | $19 985 000 | 3 500 000 | 1,89% | Acciones |
| MORGAN STANLEY | $17 954 827 | 3 144 453 | 1,70% | Acciones |
| Palo Alto Investors LP | $16 833 594 | 2 948 090 | 1,59% | Acciones |
| Balyasny Asset Management L.P. | $16 164 873 | 2 830 976 | 1,53% | Acciones |
| Nuveen, LLC | $15 788 607 | 2 765 080 | 1,49% | Acciones |
| Qube Research & Technologies Ltd | $15 702 277 | 2 749 961 | 1,48% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12 829 228 | 2 246 800 | 1,21% | Acciones |
| Opaleye Management Inc. | $9 789 515 | 1 714 451 | 0,93% | Acciones |
| Logos Global Management LP | $8 565 000 | 1 500 000 | 0,81% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $8 550 585 | 1 497 756 | 0,81% | Acciones |
| Point72 Asset Management, L.P. | $7 895 211 | 1 382 699 | 0,75% | Acciones |
| NORTHERN TRUST CORP | $7 720 182 | 1 352 046 | 0,73% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7 182 032 | 1 257 799 | 0,68% | Acciones |
| Tetragon Partners GP Ltd | $7 094 418 | 1 242 455 | 0,67% | Acciones |
| Candriam S.C.A. | $6 817 695 | 1 195 142 | 0,64% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $6 765 956 | 1 184 931 | 0,64% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $6 312 120 | 1 105 450 | 0,60% | Acciones |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $5 923 360 | 1 037 366 | 0,56% | Acciones |
| JPMORGAN CHASE & CO | $5 593 995 | 1 004 308 | 0,53% | Acciones |
| WELLS FARGO & COMPANY/MN | $5 584 694 | 978 055 | 0,53% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $5 526 857 | 967 926 | 0,52% | Acciones |
| KENNEDY CAPITAL MANAGEMENT LLC | $5 129 830 | 898 394 | 0,48% | Acciones |
| Ishara Investments LP | $4 682 200 | 820 000 | 0,44% | Acciones |
| Ensign Peak Advisors, Inc | $4 570 946 | 800 516 | 0,43% | Acciones |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $4 213 609 | 737 935 | 0,40% | Acciones |
| Y-Intercept (Hong Kong) Ltd | $4 194 480 | 734 585 | 0,40% | Acciones |
| Russell Investments Group, Ltd. | $4 027 213 | 705 291 | 0,38% | Acciones |
| AQR CAPITAL MANAGEMENT LLC | $3 950 245 | 691 812 | 0,37% | Acciones |
| Parkman Healthcare Partners LLC | $3 660 276 | 641 029 | 0,35% | Acciones |
| UBS Group AG | $3 557 866 | 623 094 | 0,34% | Acciones |
| DEUTSCHE BANK AG\ | $3 520 153 | 616 489 | 0,33% | Acciones |
| BANK OF AMERICA CORP /DE/ | $3 507 002 | 614 186 | 0,33% | Acciones |
| CITADEL ADVISORS LLC | $3 406 483 | 596 582 | 0,32% | Acciones |
Activistas y propietarios del %+ 5 3 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Satter Muneer A | 21 de noviembre de 2025 | 7,20% | Enmienda | · | SEC |
| Muneer A. Satter ×2 presentaciones | 17 de febrero de 2023 | · | Presentación inicial | · | SEC |
| Clarus Lifesciences III, L.P., Clarus Ventures III GP, L.P., Blackstone Clarus III L.L.C., Blackstone Holdings II L.P., Blackstone Holdings I/II GP L.L.C., Blackstone Inc., Blackstone Group Management L.L.C., Stephen A. Schwarzman ×2 presentaciones | 27 de agosto de 2021 | · | Presentación inicial | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Informantes de la empresa 17 insiders · 8 directivos · 10 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Douglas Love | PRESIDENT AND CEO | 24 de septiembre de 2026 P | 390 476 | 1 | 0 | $99 829 |
| Jennifer Lew | EVP & CHIEF FINANCIAL OFFICER | 2 de marzo de 2026 S | 170 700 | 0 | 2 | $-70 281 |
| Ted Yednock | EVP & CHIEF INNOVATION OFFICER | 11 de junio de 2026 M | 184 807 | 0 | 2 | $-70 317 |
| Dean Richard Artis | EVP & CHIEF SCIENTIFIC OFFICER | 2 de marzo de 2026 S | 180 093 | 0 | 2 | $-58 983 |
| Michael Overdorf | EVP & CHIEF BUSINESS OFFICER | 2 de marzo de 2026 S | 182 625 | 0 | 2 | $-55 265 |
| Jamie Dananberg | CHIEF MEDICAL OFFICER | 2 de marzo de 2026 S | 123 582 | 0 | 2 | $-58 582 |
| Larry Mattheakis | EVP & Chief Scientific Officer | 11 de julio de 2022 A | 17 188 | 0 | 0 | $0 |
| Sanjay Chandru Keswani | EVP & Chief Medical Officer | 11 de febrero de 2022 A | 12 500 | 0 | 0 | $0 |
| Mark S. Blumenkranz | Consejero | 10 de agosto de 2026 A | · | 0 | 0 | $0 |
| Bettina M. Cockroft | Consejero | 11 de junio de 2026 A | · | 0 | 0 | $0 |
| William H. Carson | Consejero | 11 de junio de 2026 A | 78 405 | 6 | 0 | $193 296 |
| Jung Choi | Consejero | 11 de junio de 2026 A | 33 000 | 1 | 0 | $138 270 |
| William D. Waddill | Consejero | 11 de junio de 2026 A | · | 0 | 0 | $0 |
| William A Jones JR | Consejero | 11 de junio de 2026 A | · | 0 | 0 | $0 |
| Satter Muneer A | Consejero | 11 de junio de 2026 A | 10 342 134 | 6 | 0 | $11 974 803 |
| Thomas G Wiggans | Consejero | 5 de junio de 2025 A | · | 0 | 0 | $0 |
| Ricky Sun | Consejero | 2 de junio de 2021 A | · | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Propiedad de ETFs Mantenido por 31 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0,72% | 65 989 NS | 31 de julio de 2026 | N-PORT |
| IBRN · iShares Trust | 0,62% | 11 173 SH | 11 de septiembre de 2026 | Diario |
| LABU · Direxion Shares ETF Trust | 0,22% | 211 825 NS | 31 de julio de 2026 | N-PORT |
| IWC · iShares Trust | 0,15% | 529 206 SH | 11 de septiembre de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,13% | 451 913 SH | 19 de agosto de 2026 | Diario |
| FFSM · FIDELITY COVINGTON TRUST | 0,11% | 311 203 NS | 31 de julio de 2026 | N-PORT |
| PWS · Pacer Funds Trust | 0,06% | 2 894 NS | 31 de julio de 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,06% | 37 296 SH | 1 de octubre de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,05% | 13 416 SH | 1 de octubre de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,05% | 166 500 SH | 19 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,05% | 1 238 553 SH | 11 de septiembre de 2026 | Diario |
| IWO · iShares Trust | 0,04% | 1 460 473 SH | 11 de septiembre de 2026 | Diario |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,03% | 210 621 SH | 1 de octubre de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,03% | 893 974 SH | 19 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,03% | 74 211 NS | 31 de julio de 2026 | N-PORT |
| IWM · iShares Trust | 0,02% | 3 987 933 SH | 11 de septiembre de 2026 | Diario |
| DFAS · Dimensional ETF Trust | 0,01% | 326 558 NS | 31 de julio de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 1 754 465 SH | 19 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,01% | 366 971 SH | 19 de agosto de 2026 | Diario |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 56 295 NS | 31 de julio de 2026 | N-PORT |
| WSML · iShares Trust | 0,00% | 7 332 SH | 11 de septiembre de 2026 | Diario |
| DCOR · Dimensional ETF Trust | 0,00% | 15 800 NS | 31 de julio de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 218 518 NS | 31 de julio de 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 54 863 SH | 11 de septiembre de 2026 | Diario |
| ITOT · iShares Trust | 0,00% | 219 924 SH | 11 de septiembre de 2026 | Diario |
| DFAU · Dimensional ETF Trust | 0,00% | 19 704 NS | 31 de julio de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 22 484 NS | 31 de julio de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 4 970 636 SH | 19 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 13 754 SH | 19 de agosto de 2026 | Diario |
| ISCB · iShares Trust | · | 6 291 SH | 11 de septiembre de 2026 | Diario |
| ISCV · iShares Trust | · | 31 162 SH | 11 de septiembre de 2026 | Diario |
ANNX Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
calificación · 17 analistas
COMPRA
Objetivo mediano
$14.00
+234,1%
4 23,5%
Compra fuerte
10 58,8%
Compra
3 17,6%
Mantener
0 0,0%
Venta
0 0,0%
Venta fuerte
Precio objetivo a 12 meses
7 analistas · 2026-09-28Objetivo medio $15.29 +264,8%
← Por Debajo de Todos los Objetivos
Precio Actual $4.19
Mín$7.00
Media$15.29
Máx$27.00
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
Base del ejercicio fiscal, precios al cierre del último ejercicio fiscal de cada empresa.
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| ANNX | $750M | -3.7 | · | · | -100.7% | · |
| JBIO | $761M | -4.8 | · | · | -47.7% | · |
| ARDX | $1.42B | -22.4 | 22.1% | -15.1% | -40.2% | · |
| OBX | · | · | · | · | · | · |
| AVTX | $336M | -3.1 | -86.6% | -132642.4% | -83.4% | · |
| DSGN | $567M | -7.7 | · | · | -32.8% | · |
| GERN | $845M | -10.2 | -60.2% | · | -34.4% | · |
| ACHV | · | -4.0 | · | · | · | · |
| CADL | $310M | -7.8 | · | · | -53.7% | · |
| FDMT | $432M | -3.1 | 230194.6% | -164.4% | -30.2% | · |
Mis Métricas Tu lista de seguimiento personal — filas seleccionadas de Fundamentales Completos
Seleccione las métricas que le importan: haga clic en el + junto a cualquier fila en Fundamentales completos arriba.
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Fuente: SEC 10-Q presentada el Ago 12, 2026