LYEL Lyell Immunopharma, Inc. - Common Stock
LYEL Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
LYEL Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
LYEL Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 3 23,1%
- Compra 8 61,5%
- Mantener 1 7,7%
- Venta 1 7,7%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
7 analistas · 2026-08-14Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-1.92 | $-2.06 | 0.14% |
| 31 de marzo de 2026 | $-1.10 | $-2.41 | 1.3% |
| 31 de diciembre de 2025 | $-7.50 | $-2.28 | -5.2% |
| 30 de septiembre de 2025 | $-2.13 | $-2.70 | 0.57% |
| 30 de junio de 2025 | $-2.89 | $-3.65 | 0.77% |
| 31 de marzo de 2025 | $-3.54 | $-3.67 | 0.13% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| LYEL | $654M | -1.9 | -41.0% | -762355.6% | -100.3% | — |
| SABS | — | — | — | — | — | — |
| ABEO | $290M | 5.2 | 147.5% | 1223.1% | 44.1% | — |
| IMRX | — | -5.2 | — | — | -45.3% | — |
| TLSI | — | — | — | — | — | — |
| IKT | $270M | -4.2 | 111.0% | -1299.0% | -38.2% | — |
| AGEN | $111M | — | 10.4% | -2.7% | 1.0% | — |
| FATE | $113M | -0.9 | -51.2% | -2051.1% | -58.2% | — |
| VNDA | $521M | -2.4 | 8.7% | -102.0% | -54.2% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 13
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue | $36.0K | $61.0K | $130.0K | $85M | $11M | $8M | |
| R&D Expense | · | · | $183M | $159M | $139M | $182M | |
| SG&A Expense | $45M | $52M | $67M | $117M | $89M | $47M | |
| Operating Expenses | $269M | $359M | $247M | $272M | $225M | $220M | |
| Operating Income | $-269M | $-359M | $-247M | $-187M | $-215M | $-212M | |
| Other Non-op | $-18M | $5M | $2M | $2M | $-161.0K | $2M | |
| Income Tax | $0 | · | · | · | · | · | |
| Net Income | $-274M | $-343M | $-235M | $-183M | $-250M | $-204M | |
| EPS (Basic) | $-16.06 | $-26.23 | $-18.70 | $-0.74 | $-1.84 | $-15.69 | |
| EPS (Diluted) | $-16.06 | $-26.23 | $-18.70 | $-0.74 | $-1.84 | $-15.69 | |
| Shares (Basic) | 17,093,000 | 13,074,000 | 12,549,000 | 247,080,000 | 135,918,000 | 13,258,000 | |
| Shares (Diluted) | 17,093,000 | 13,074,000 | 12,549,000 | 247,080,000 | 135,918,000 | 13,258,000 | |
| EBITDA | $-258M | $-339M | $-227M | $-169M | $-201M | · |
Balance general 21
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $60M | $106M | $146M | $124M | $294M | $140M | |
| Short-term Investments | $187M | $265M | $401M | $517M | $321M | $472M | |
| Prepaid Expense | $14M | $9M | $8M | $11M | $11M | $5M | |
| Current Assets | $261M | $380M | $555M | $651M | $626M | $618M | |
| PP&E (Net) | $35M | $48M | $103M | $123M | $120M | $77M | |
| PP&E (Gross) | $109M | $119M | $154M | $155M | $135M | $82M | |
| Accum. Depreciation | $74M | $71M | $52M | $32M | $15M | $5M | |
| Other Non-current Assets | $5M | $5M | $4M | $5M | $3M | $3M | |
| Total Assets | $340M | $491M | $750M | $938M | $1.13B | $908M | |
| Accounts Payable | $3M | $5M | $5M | $4M | $3M | $9M | |
| Current Liabilities | $49M | $54M | $35M | $37M | $47M | $49M | |
| Capital Leases | $42M | $51M | $57M | $63M | $67M | $51M | |
| Other Non-current Liabilities | $517.0K | $3M | $4M | $4M | $5M | $532.0K | |
| Total Liabilities | $92M | $108M | $95M | $104M | $198M | $190M | |
| Common Stock | $2.0K | $1.0K | $25.0K | $25.0K | $24.0K | $2.0K | |
| Paid-in Capital | $1.87B | $1.73B | $1.66B | $1.61B | $1.52B | $41M | |
| Retained Earnings | $-1.62B | $-1.35B | $-1.00B | $-767M | $-584M | $-334M | |
| AOCI | $242.0K | $291.0K | $-94.0K | $-8M | $-2M | $256.0K | |
| Stockholders' Equity | $248M | $383M | $655M | $833M | $930M | $-293M | |
| Liabilities + Equity | $340M | $491M | $750M | $938M | $1.13B | $908M | |
| Shares Outstanding | 21,251,000 | 14,744,000 | 12,698,000 | 12,479,000 | 242,738,000 | 15,570,000 |
Flujo de Efectivo 13
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $12M | $20M | $20M | $18M | $14M | $4M | |
| Stock-based Comp | $42M | $33M | $47M | $82M | $62M | $33M | |
| Restructuring | · | · | $6M | · | · | · | |
| Other Non-cash | $71M | $128M | $4M | $-86M | $48M | · | |
| Operating Cash Flow | $-150M | $-162M | $-164M | $-170M | $-126M | $-161M | |
| CapEx | $780.0K | $464.0K | $3M | $24M | $66M | $51M | |
| Investing Cash Flow | $54M | $122M | $184M | $-12M | $-122M | $-274M | |
| Stock Issued | $50M | $0 | $0 | · | · | · | |
| Stock Repurchased | · | · | · | $0 | $0 | $12M | |
| Net Stock Activity | $50M | · | · | $0 | $0 | · | |
| Financing Cash Flow | $50M | $1M | $2M | $11M | $401M | $477M | |
| Net Change in Cash | $-46M | $-39M | $22M | $-170M | $153M | $42M | |
| Free Cash Flow | $-151M | $-163M | $-166M | $-194M | $-192M | · |
Rentabilidad 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Operating Margin | -748344.4% | -588123.0% | -190006.1% | -220.9% | -2016.7% | · | |
| Net Margin | -762355.6% | -562285.2% | -180486.1% | -216.2% | -2349.5% | · | |
| EBITDA Margin | -716291.7% | -555941.0% | -174429.2% | -199.6% | -1888.8% | · | |
| ROA | -66.1% | -55.3% | -27.8% | -17.7% | -24.6% | · | |
| ROE | -100.3% | -75.1% | -34.7% | -22.1% | -26.1% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 5.3 | 7.1 | 16.1 | 17.6 | 13.4 | · | |
| Quick Ratio | 5.0 | 6.9 | 15.8 | 17.3 | 13.2 | · |
Eficiencia 1
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | · |
Tasas de Crecimiento 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue YoY | -41.0% | -53.1% | -99.9% | 695.1% | 37.3% | · | |
| Revenue CAGR 3Y | -92.5% | -82.1% | -74.4% | · | · | · | |
| Revenue CAGR 5Y | -65.8% | · | · | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue TTM | $36.0K | $61.0K | $130.0K | $85M | $11M | · | |
| Net Income TTM | $-274M | $-343M | $-235M | $-183M | $-250M | · | |
| Market Cap | $654M | $3.77B | $9.85B | $17.32B | $37.58B | · | |
| P/E | -1.9 | -0.5 | -2.1 | -93.8 | -84.1 | · | |
| P/S | 18169.6 | 61875.6 | 75796.7 | 204.5 | 3528.2 | · | |
| P/B | 2.6 | 9.9 | 15.0 | 20.8 | 40.4 | · | |
| P / Tangible Book | 2.6 | 9.9 | 15.0 | 20.8 | 40.4 | · | |
| P / Cash Flow | -4.4 | -23.2 | -60.2 | -102.1 | -297.6 | · | |
| P / FCF | -4.3 | -23.2 | -59.2 | -89.4 | -196.0 | · | |
| Earnings Yield | -52.2% | -204.9% | -48.2% | -1.1% | -1.2% | · |
Estado de resultados 12
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $4.0K | $2.0K | $6.0K | $15.0K | $8.0K | $7.0K | $11.0K | $34.0K | $13.0K | $3.0K | $13.0K | $25.0K | $27.0K | $65.0K | $48M | $3.0K | |
| R&D Expense | $40M | $37M | · | $28M | $35M | $43M | · | $40M | $40M | $43M | · | $44M | $47M | $45M | · | $42M | |
| SG&A Expense | $10M | $10M | $11M | $11M | $10M | $14M | $15M | $12M | $12M | $13M | $13M | $16M | $19M | $19M | $26M | $26M | |
| Operating Expenses | $47M | $44M | $128M | $37M | $47M | $57M | $201M | $51M | $52M | $56M | $60M | $59M | $66M | $63M | $63M | $66M | |
| Operating Income | $-47M | $-44M | $-128M | $-37M | $-47M | $-57M | $-201M | $-51M | $-52M | $-56M | $-60M | $-59M | $-66M | $-63M | $-15M | $-66M | |
| Other Non-op | $398.0K | $18M | $-16M | $-5M | $1M | $1M | $4M | $-43.0K | $-645.0K | $1M | $-506.0K | $2M | $-326.0K | $1M | $3M | $-1M | |
| Net Income | $-45M | $-24M | $-141M | $-39M | $-43M | $-52M | $-192M | $-45M | $-46M | $-61M | $-53M | $-51M | $-64M | $-67M | $-8M | $-70M | |
| EPS (Basic) | $-1.92 | $-1.10 | $-10.86 | $-2.13 | $-2.89 | $-3.54 | $-18.92 | $-3.48 | $-3.59 | $-0.24 | $-17.97 | $-0.20 | $-0.26 | $-0.27 | $-0.03 | $-0.28 | |
| EPS (Diluted) | $-1.92 | $-1.10 | $-10.86 | $-2.13 | $-2.89 | $-3.54 | $-18.92 | $-3.48 | $-3.59 | $-0.24 | $-17.97 | $-0.20 | $-0.26 | $-0.27 | $-0.03 | $-0.28 | |
| Shares (Basic) | 23,364,000 | 21,876,000 | -311,066,000 | 18,268,000 | 14,793,000 | 14,755,000 | -266,763,000 | 12,815,000 | 12,770,000 | 254,252,000 | -738,564,000 | 251,318,000 | 250,204,000 | 249,591,000 | -491,730,000 | 248,320,000 | |
| Shares (Diluted) | 23,364,000 | 21,876,000 | -311,066,000 | 18,268,000 | 14,793,000 | 14,755,000 | -266,763,000 | 12,815,000 | 12,770,000 | 254,252,000 | -738,564,000 | 251,318,000 | 250,204,000 | 249,591,000 | -491,730,000 | 248,320,000 | |
| EBITDA | $-47M | $-42M | · | $-37M | $-47M | $-54M | · | $-51M | $-52M | $-51M | · | $-59M | $-66M | $-58M | · | $-66M |
Balance general 21
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $73M | $91M | $60M | $124M | $99M | $120M | $106M | $100M | $133M | $126M | $146M | $286M | $224M | $109M | $124M | $116M | |
| Short-term Investments | $131M | $163M | $187M | $196M | $178M | $181M | $265M | $340M | $358M | $401M | · | $289M | $371M | $503M | · | $532M | |
| Prepaid Expense | $9M | $13M | $14M | $9M | $5M | $8M | $9M | $9M | $9M | $8M | · | $11M | $11M | $12M | · | $12M | |
| Current Assets | $214M | $267M | $261M | $328M | $282M | $309M | $380M | $450M | $500M | $534M | · | $587M | $606M | $624M | · | $660M | |
| PP&E (Net) | $31M | $33M | $35M | $37M | $39M | $44M | $48M | $88M | $93M | $98M | · | $108M | $114M | $119M | · | $126M | |
| PP&E (Gross) | · | · | $109M | · | · | · | $119M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $74M | · | · | · | $71M | · | · | · | · | · | · | · | · | · | |
| Other Non-current Assets | $6M | $5M | $5M | $3M | $3M | $3M | $5M | $5M | $4M | $4M | · | $4M | $5M | $5M | · | $3M | |
| Total Assets | $311M | $351M | $340M | $408M | $385M | $430M | $491M | $619M | $654M | $694M | · | $795M | $835M | $880M | · | $977M | |
| Accounts Payable | $4M | $5M | $3M | $3M | $3M | $4M | $5M | $4M | $4M | $5M | · | $4M | $6M | $6M | · | $5M | |
| Current Liabilities | $40M | $37M | $49M | $32M | $37M | $41M | $54M | $34M | $31M | $32M | · | $35M | $34M | $31M | · | $51M | |
| Capital Leases | $37M | $39M | $42M | $44M | $47M | $49M | $51M | $51M | $53M | $55M | · | $59M | $60M | $62M | · | $65M | |
| Other Non-current Liabilities | $537.0K | $527.0K | $517.0K | $3M | $3M | $3M | $3M | $4M | $3M | $4M | · | $4M | $4M | $4M | · | $4M | |
| Total Liabilities | $77M | $77M | $92M | $79M | $87M | $93M | $108M | $89M | $88M | $91M | · | $97M | $98M | $97M | · | $157M | |
| Common Stock | $2.0K | $2.0K | $2.0K | $2.0K | $1.0K | $30.0K | $1.0K | $26.0K | $26.0K | $25.0K | · | $25.0K | $25.0K | $25.0K | · | $25.0K | |
| Paid-in Capital | $1.92B | $1.92B | $1.87B | $1.81B | $1.74B | $1.73B | $1.73B | $1.68B | $1.68B | $1.67B | · | $1.65B | $1.64B | $1.62B | · | $1.59B | |
| Retained Earnings | $-1.69B | $-1.64B | $-1.62B | $-1.48B | $-1.44B | $-1.40B | $-1.35B | $-1.15B | $-1.11B | $-1.06B | · | $-949M | $-898M | $-834M | · | $-759M | |
| AOCI | $-158.0K | $-9.0K | $242.0K | $201.0K | $57.0K | $158.0K | $291.0K | $760.0K | $-397.0K | $-404.0K | · | $-1M | $-2M | $-4M | · | $-10M | |
| Stockholders' Equity | $234M | $274M | $248M | $329M | $299M | $337M | $383M | $531M | $567M | $603M | $655M | $698M | $737M | $784M | $833M | $820M | |
| Liabilities + Equity | $311M | $351M | $340M | $408M | $385M | $430M | $491M | $619M | $654M | $694M | · | $795M | $835M | $880M | · | $977M | |
| Shares Outstanding | 23,397,000 | 23,328,000 | 21,251,000 | 19,294,000 | 14,831,000 | 295,284,000 | 14,744,000 | 256,564,000 | 255,948,000 | 254,927,000 | 12,698,000 | 251,869,000 | 251,027,000 | 249,609,000 | 249,567,000 | 249,240,000 |
Flujo de Efectivo 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $3M | $3M | $3M | $5M | $5M | $5M | $5M | $5M | $5M | $5M | $5M | $5M | $5M | |
| Stock-based Comp | $5M | $4M | $26M | $5M | $5M | $6M | $8M | $8M | $8M | $9M | $8M | $11M | $14M | $14M | $18M | $19M | |
| Other Non-cash | · | $-21M | · | · | · | $-12M | · | · | · | $4M | · | · | · | $2M | · | · | |
| Operating Cash Flow | $-34M | $-39M | $-32M | $-29M | $-34M | $-55M | $-47M | $-35M | $-38M | $-42M | $-41M | $-38M | $-39M | $-46M | $-40M | $-37M | |
| CapEx | $256.0K | $89.0K | $304.0K | $62.0K | $168.0K | $246.0K | $44.0K | $59.0K | $331.0K | $30.0K | $25.0K | $195.0K | $933.0K | $2M | $5M | $3M | |
| Investing Cash Flow | $16M | $17M | $-31M | $3M | $13M | $69M | $54M | $2M | $45M | $22M | $-101M | $100M | $153M | $32M | $47M | $-57M | |
| Stock Issued | · | · | $0 | · | · | · | $0 | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $522.0K | $52M | $222.0K | $50M | $183.0K | $1.0K | $437.0K | $0 | $862.0K | $27.0K | $759.0K | $-143.0K | $1M | $-69.0K | $863.0K | $5M | |
| Net Change in Cash | $-18M | $31M | $-63M | $25M | $-22M | $15M | $7M | $-33M | $8M | $-20M | $-141M | $62M | $115M | $-14M | $7M | $-89M | |
| Free Cash Flow | · | $-39M | · | · | · | $-55M | · | · | · | $-42M | · | · | · | $-48M | · | · |
Rentabilidad 5
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1183425.0% | -2213050.0% | · | -248353.3% | -589250.0% | -819528.6% | · | -148544.1% | -396369.2% | -1852500.0% | · | -236156.0% | -244092.6% | -96240.0% | · | -2214566.7% | |
| Net Margin | -1118875.0% | -1207650.0% | · | -258973.3% | -533550.0% | -745642.9% | · | -131126.5% | -352376.9% | -2022233.3% | · | -203412.0% | -236629.6% | -103013.9% | · | -2341800.0% | |
| EBITDA Margin | -1183425.0% | -2096450.0% | · | -248353.3% | -589250.0% | -770371.4% | · | -148544.1% | -396369.2% | -1685033.3% | · | -236156.0% | -244092.6% | -88506.2% | · | -2214566.7% | |
| ROA | -12.8% | -6.2% | · | -7.6% | -8.2% | -9.3% | · | -6.3% | -6.2% | -7.7% | · | -5.7% | -6.9% | -6.9% | · | -6.5% | |
| ROE | -16.8% | -7.9% | · | -9.0% | -9.9% | -11.1% | · | -7.3% | -7.0% | -8.8% | · | -6.7% | -8.0% | -8.0% | · | -7.8% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.4 | 7.2 | · | 10.3 | 7.6 | 7.5 | · | 13.4 | 16.2 | 16.5 | · | 16.7 | 17.6 | 20.3 | · | 12.9 | |
| Quick Ratio | 5.1 | 6.9 | · | 10.0 | 7.5 | 7.3 | · | 13.1 | 15.9 | 16.3 | · | 16.4 | 17.3 | 19.9 | · | 12.7 |
Eficiencia 1
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $29.0K | $32.0K | · | $64.0K | $62.0K | $57.0K | · | $75.0K | $68.0K | $120.0K | · | $120.0K | $36M | $36M | · | $39M | |
| Net Income TTM | $-150M | $-158M | · | $-178M | $-185M | $-203M | · | $-202M | $-221M | $-242M | · | $-252M | $-237M | $-242M | · | $-224M | |
| Market Cap | $329M | $468M | · | $313M | $131M | $3.18B | · | $7.08B | $7.42B | $11.37B | · | $7.40B | $15.97B | $11.78B | · | $36.54B | |
| P/E | -1.7 | -2.1 | · | -1.9 | -0.9 | -1.4 | · | -3.7 | -6.8 | -46.0 | · | -29.1 | -66.2 | -48.2 | · | -161.1 | |
| P/S | 11335.4 | 14623.7 | · | 4895.9 | 2114.6 | 55741.3 | · | 94415.6 | 109154.3 | 94747.9 | · | 61707.9 | 445.5 | 324.0 | · | 935.6 | |
| P/B | 1.4 | 1.7 | · | 1.0 | 0.4 | 9.4 | · | 13.3 | 13.1 | 18.9 | · | 10.6 | 21.7 | 15.0 | · | 44.6 | |
| P / Tangible Book | 1.4 | 1.7 | · | 1.0 | 0.4 | 9.4 | · | 13.3 | 13.1 | 18.9 | · | 10.6 | 21.7 | 15.0 | · | 44.6 | |
| P / Cash Flow | · | -12.2 | · | · | · | -58.0 | · | · | · | -270.6 | · | · | · | -254.9 | · | · | |
| P / FCF | · | -12.1 | · | · | · | -57.8 | · | · | · | -270.4 | · | · | · | -246.8 | · | · | |
| Earnings Yield | -57.2% | -48.2% | · | -53.4% | -114.7% | -69.6% | · | -27.2% | -14.8% | -2.2% | · | -3.4% | -1.5% | -2.1% | · | -0.62% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $36.0K | $61.0K | $130.0K | $85M | $11M |
| Margen Operativo % | -748344.4% | -588123.0% | -190006.1% | -220.9% | -2016.7% |
| Beneficio neto | $-274M | $-343M | $-235M | $-183M | $-250M |
| EPS Diluido | $-16.06 | $-26.23 | $-18.70 | $-0.74 | $-1.84 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 5.3 | 7.1 | 16.1 | 17.6 | 13.4 |
| Ratio Rápido | 5.0 | 6.9 | 15.8 | 17.3 | 13.2 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-151M | $-163M | $-166M | $-194M | $-192M |
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Propietarios institucionales (13F) 94 declarantes · $203.2M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 30 (+14 vs trimestre anterior) | 9 (+3 vs trimestre anterior) | 25 (+1 vs trimestre anterior) | 19 (+11 vs trimestre anterior) | +295K |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| ARCH Venture Management, LLC | $45 525 211 | 3 247 162 | 22,41% | Acciones |
| MWG Caph Ltd | $31 029 810 | 1 008 116 | 15,27% | Acciones |
| GSK plc | $21 252 859 | 1 512 659 | 10,46% | Acciones |
| MWG Management Ltd. | $16 371 804 | 1 008 116 | 8,06% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $11 054 175 | 786 774 | 5,44% | Acciones |
| Orland Properties Ltd | $10 603 507 | 754 698 | 5,22% | Acciones |
| Almitas Capital LLC | $8 168 768 | 581 407 | 4,02% | Acciones |
| Foresite Capital Management V, LLC | $6 693 223 | 476 386 | 3,29% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $5 162 996 | 367 473 | 2,54% | Acciones |
| Opaleye Management Inc. | $4 833 551 | 344 025 | 2,38% | Acciones |
| venBio Partners LLC | $4 744 643 | 337 697 | 2,34% | Acciones |
| Alphabet Inc. | $4 120 247 | 293 256 | 2,03% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $3 712 787 | 264 152 | 1,83% | Acciones |
| VANGUARD GROUP INC | $2 675 552 | 86 925 | 1,32% | Acciones |
| STATE STREET CORP | $2 603 774 | 185 322 | 1,28% | Acciones |
| HSG Holding Ltd | $2 139 801 | 152 299 | 1,05% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $1 829 169 | 130 190 | 0,90% | Acciones |
| Qube Research & Technologies Ltd | $1 552 961 | 110 531 | 0,76% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1 511 359 | 107 570 | 0,74% | Acciones |
| Velan Capital Investment Management LP | $1 475 250 | 105 000 | 0,73% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $1 307 985 | 93 095 | 0,64% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1 291 069 | 91 891 | 0,64% | Acciones |
| MIC Capital Management UK LLP | $1 222 743 | 87 028 | 0,60% | Acciones |
| GOLDMAN SACHS GROUP INC | $1 219 245 | 86 779 | 0,60% | Acciones |
| MARSHALL WACE, LLP | $1 188 350 | 84 580 | 0,58% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $779 269 | 55 464 | 0,38% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $743 624 | 52 927 | 0,37% | Acciones |
| Squarepoint Ops LLC | $594 624 | 42 322 | 0,29% | Acciones |
| Ikarian Capital, LLC | $577 188 | 41 081 | 0,28% | Acciones |
| JANE STREET GROUP, LLC | $476 309 | 33 901 | 0,23% | Acciones |
| CANADA PENSION PLAN INVESTMENT BOARD | $413 225 | 29 411 | 0,20% | Acciones |
| Point72 Asset Management, L.P. | $366 424 | 26 080 | 0,18% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $363 895 | 25 900 | 0,18% | Opción de compra |
| AMERICAN CENTURY COMPANIES INC | $344 787 | 24 540 | 0,17% | Acciones |
| Jump Financial, LLC | $308 482 | 21 956 | 0,15% | Acciones |
| Clearstead Advisors, LLC | $280 410 | 19 958 | 0,14% | Acciones |
| EntryPoint Capital, LLC | $272 710 | 19 410 | 0,13% | Acciones |
| CITADEL ADVISORS LLC | $262 665 | 18 695 | 0,13% | Acciones |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $252 900 | 18 000 | 0,12% | Acciones |
| CITADEL ADVISORS LLC | $251 495 | 17 900 | 0,12% | Opción de venta |
| Susquehanna Portfolio Strategies, LLC | $251 144 | 17 875 | 0,12% | Acciones |
| MORGAN STANLEY | $239 257 | 17 029 | 0,12% | Acciones |
| CITADEL ADVISORS LLC | $238 850 | 17 000 | 0,12% | Opción de compra |
| Allspring Global Investments Holdings, LLC | $226 837 | 16 145 | 0,11% | Acciones |
| RHUMBLINE ADVISERS | $217 234 | 15 462 | 0,11% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $199 510 | 14 200 | 0,10% | Opción de venta |
| Nuveen, LLC | $176 960 | 12 595 | 0,09% | Acciones |
| Graham Capital Management, L.P. | $163 008 | 11 602 | 0,08% | Acciones |
| Brevan Howard Capital Management LP | $162 376 | 11 557 | 0,08% | Acciones |
| BANK OF AMERICA CORP /DE/ | $152 737 | 10 871 | 0,08% | Acciones |
| Walleye Capital LLC | $146 837 | 10 451 | 0,07% | Acciones |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $133 545 | 9 505 | 0,07% | Acciones |
| DEUTSCHE BANK AG\ | $129 091 | 9 188 | 0,06% | Acciones |
| Bank of New York Mellon Corp | $127 799 | 9 096 | 0,06% | Acciones |
| BlackRock, Inc. | $111 051 | 7 904 | 0,05% | Acciones |
| WELLS FARGO & COMPANY/MN | $110 714 | 7 880 | 0,05% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $110 222 | 7 845 | 0,05% | Acciones |
| Vanguard Global Advisers, LLC | $72 568 | 5 165 | 0,04% | Acciones |
| CITIGROUP INC | $62 972 | 4 482 | 0,03% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $60 879 | 4 333 | 0,03% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $57 605 | 4 100 | 0,03% | Acciones |
| Invesco Ltd. | $52 716 | 3 752 | 0,03% | Acciones |
| China Universal Asset Management Co., Ltd. | $52 182 | 3 714 | 0,03% | Acciones |
| JPMORGAN CHASE & CO | $49 738 | 3 901 | 0,02% | Acciones |
| BARCLAYS PLC | $49 147 | 3 498 | 0,02% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $48 416 | 3 446 | 0,02% | Acciones |
| FMR LLC | $30 222 | 2 151 | 0,01% | Acciones |
| NORTHERN TRUST CORP | $20 583 | 1 465 | 0,01% | Acciones |
| Tower Research Capital LLC (TRC) | $19 164 | 1 364 | 0,01% | Acciones |
| Mirae Asset Global Investments Co., Ltd. | $14 668 | 1 044 | 0,01% | Acciones |
| Legal & General Group Plc | $12 884 | 917 | 0,01% | Acciones |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $12 715 | 905 | 0,01% | Acciones |
| Ameritas Investment Partners, Inc. | $11 999 | 854 | 0,01% | Acciones |
| JONES FINANCIAL COMPANIES LLLP | $11 900 | 1 025 | 0,01% | Acciones |
| Russell Investments Group, Ltd. | $10 565 | 752 | 0,01% | Acciones |
| GF FUND MANAGEMENT CO. LTD. | $6 351 | 452 | 0,00% | Acciones |
| ROYAL BANK OF CANADA | $6 000 | 418 | 0,00% | Acciones |
| Truvestments Capital LLC | $4 215 | 300 | 0,00% | Acciones |
| UBS Group AG | $3 513 | 250 | 0,00% | Acciones |
| SIMPLEX TRADING, LLC | $3 175 | 226 | 0,00% | Acciones |
| Sterling Capital Management LLC | $2 670 | 190 | 0,00% | Acciones |
| Quarry LP | $2 515 | 179 | 0,00% | Acciones |
| GROUP ONE TRADING LLC | $1 236 | 88 | 0,00% | Acciones |
| Caitong International Asset Management Co., Ltd | $955 | 68 | 0,00% | Acciones |
| ACADIAN ASSET MANAGEMENT LLC | $836 | 59 748 | 0,00% | Acciones |
| US BANCORP \DE\ | $815 | 58 | 0,00% | Acciones |
| Cornerstone Financial Management LLC | $646 | 46 | 0,00% | Acciones |
| HRT FINANCIAL LP | $513 | 36 575 | 0,00% | Acciones |
| GAMMA Investing LLC | $492 | 35 | 0,00% | Acciones |
| PRICE T ROWE ASSOCIATES INC /MD/ | $431 | 30 657 | 0,00% | Acciones |
| GSA CAPITAL PARTNERS LLP | $368 | 26 225 | 0,00% | Acciones |
| NISA INVESTMENT ADVISORS, LLC | $351 | 25 | 0,00% | Acciones |
| Optiver Holding B.V. | $281 | 20 | 0,00% | Acciones |
| CWM, LLC | $40 | 2 | 0,00% | Acciones |
Informantes de la empresa 21 insiders · 7 directivos · 10 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Elizabeth Homans | Chief Executive Officer | 16 de marzo de 2022 A | — | 0 | 0 | $0 |
| Charles W. Newton | Chief Financial Officer | 9 de febrero de 2024 A | 48 729 | 0 | 0 | $0 |
| David Shook | Chief Medical Officer | 10 de junio de 2026 S | 20 923 | 0 | 1 | $-24 989 |
| Matthew Lang | Chief Business Officer | 9 de febrero de 2024 A | 50 000 | 0 | 0 | $0 |
| Tina M. Albertson | Chief Medical Officer | 24 de febrero de 2023 A | — | 0 | 0 | $0 |
| Rahsaan Thompson | Chief Legal Officer | 24 de febrero de 2023 A | — | 0 | 0 | $0 |
| Heather D Turner | Chief General Counsel | 16 de marzo de 2022 A | — | 0 | 0 | $0 |
| Mark Bachleda | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| Elizabeth G Nabel | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| Richard Klausner | Consejero | 10 de junio de 2026 A | 930 880 | 0 | 0 | $0 |
| Sumant Ramachandra | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| Cathy Friedman | Consejero | 10 de junio de 2026 A | 236 370 | 0 | 0 | $0 |
| Otis W Brawley | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| William Jl Rieflin | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| Hans Edgar Bishop | Consejero | 8 de septiembre de 2023 A | 4 685 614 | 0 | 0 | $0 |
| Robert Nelsen | Consejero | 8 de septiembre de 2023 A | 18 206 358 | 0 | 0 | $0 |
| Innovative Cellular Therapeutics Holdings Ltd | Propietario del 10% | 27 de julio de 2026 J | 2 818 980 | 0 | 2 | $-274 |
| Veronica Sanchez Bulis | — | 10 de agosto de 2026 S | 14 799 | 0 | 2 | $-13 008 |
| Gary K. Lee | — | 10 de agosto de 2026 S | 17 677 | 0 | 2 | $-4 339 |
| Stephen J. Hill | — | 10 de agosto de 2026 S | 17 805 | 0 | 2 | $-2 960 |
| Lynn Seely | — | 10 de agosto de 2026 S | 73 488 | 0 | 5 | $-204 066 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Propiedad de ETFs Mantenido por 21 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| IWC · iShares Trust | 0,03% | 31 581 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,02% | 1 253 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,02% | 787 NS | 31 de mayo de 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,01% | 23 005 NS | 31 de mayo de 2026 | N-PORT |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,01% | 8 183 SH | 8 de agosto de 2026 | Diario |
| IWN · iShares Trust | 0,01% | 88 790 SH | 8 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,01% | 55 895 SH | 8 de agosto de 2026 | Diario |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 67 448 NS | 31 de mayo de 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,00% | 9 023 SH | 8 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,00% | 222 372 SH | 8 de agosto de 2026 | Diario |
| DFAS · Dimensional ETF Trust | 0,00% | 12 766 NS | 30 de abril de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 339 NS | 30 de abril de 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 9 101 NS | 31 de mayo de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 1 396 NS | 30 de abril de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 163 755 SH | 8 de agosto de 2026 | Diario |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 604 461 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,00% | 54 398 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 1 151 SH | 8 de agosto de 2026 | Diario |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 346 NS | 31 de mayo de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 409 NS | 30 de abril de 2026 | N-PORT |
| VHT · VANGUARD WORLD FUND | 0,00% | 28 159 SH | 8 de agosto de 2026 | Diario |