XENE Xenon Pharmaceuticals Inc. - Common Shares
$64,28
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 6, 2026
Rango 52S
$36–$73
77% of range
Calificación del Analista
BUY
26 analysts
Precio Objetivo
$81
+26% upside
P/E (TTM)
-14.7
ROE
-56.9%
Margen de Beneficio Neto
-4612.1%
Acerca de Xenon Pharmaceuticals Inc. - Common Shares Descripción general de la empresa de Wikipedia
XENE Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$64.28
Capitalización Bursátil
$5.14B
P/E (TTM)
-14.7
BPA (TTM)
$-4.36
Ingresos (TTM)
$8M
Rendimiento div.
—
ROE
-56.9%
Deuda/Capital
—
Rango 52S
$36 – $73
XENE Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
$8M
2016-12-31
→
2025-12-31
BPA
$-4.36
2016-12-31
→
2025-12-31
Flujo de caja libre
$-280M
2016-12-31
→
2025-12-31
Márgenes
-4612.1%
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
XENE
Mediana de Pares
P/E (TTM)
-14.7
—
P/S (TTM) (P/V (TTM))
685.7
418.4
P/B (P/C)
8.8
2.3
Price / FCF (Precio / FCF)
-18.4
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
XENE
Mediana de Pares
Operating Margin (Margen Operativo)
-4974.3%
—
Net Profit Margin (Margen de Beneficio Neto)
-4612.1%
-549.8%
ROA
-48.3%
-41.8%
ROE
-56.9%
-54.1%
ROIC
-64.3%
—
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
XENE
Mediana de Pares
Current Ratio (Ratio corriente)
13.4
12.6
Quick Ratio (Ratio Rápido)
13.1
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
XENE
Mediana de Pares
Revenue CAGR 3Y (Ingresos CAGR 3A)
-7.4%
—
Revenue CAGR 5Y (Ingresos CAGR 5A)
-25.3%
—
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
XENE
Mediana de Pares
XENE Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
26 analistas
- Compra fuerte 11 42,3%
- Compra 14 53,8%
- Mantener 1 3,8%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
19 analistas · 2026-08-16
Mediana
$80.00
← Por Debajo de Todos los Objetivos
$64.28
Mín
$69.00
Máx
$100.00
Objetivo mediano
$80.00
+24,5%
Objetivo medio
$81.30
+26,5%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
0.01%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-1.11 | $-1.16 | 0.05% |
| 31 de marzo de 2026 | $-1.17 | $-1.21 | 0.04% |
| 31 de diciembre de 2025 | $-1.31 | $-1.22 | -0.09% |
| 30 de septiembre de 2025 | $-1.15 | $-1.18 | 0.03% |
| 30 de junio de 2025 | $-1.07 | $-1.01 | -0.06% |
| 31 de marzo de 2025 | $-0.83 | $-0.93 | 0.10% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| XENE | $3.59B | -10.3 | — | -4612.1% | -56.9% | — |
| AUPH | $2.11B | 7.7 | 20.4% | 101.5% | 62.7% | — |
| ABUS | $926M | -28.3 | 128.2% | -237.9% | -42.0% | — |
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
| ACOG | $141M | -5.5 | — | -202.2% | -43.8% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 16
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $8M | $0 | $0 | $9M | $18M | $32M | $7M | · | $311.0K | $2M | $16M | $28M | |
| R&D Expense | $301M | $210M | $168M | $106M | $75M | $51M | $39M | $24M | $26M | $20M | $15M | $12M | |
| SG&A Expense | $80M | $69M | $47M | $33M | $22M | $13M | $11M | $8M | $7M | $7M | $10M | $5M | |
| Operating Expenses | $381M | $279M | $214M | $139M | $97M | $63M | $50M | $38M | $33M | $27M | $25M | $17M | |
| Operating Income | $-373M | $-279M | $-214M | $-129M | $-79M | $-31M | $-43M | $-38M | $-33M | $-25M | $-9M | $11M | |
| Interest Expense | · | · | · | · | · | $484.0K | $1M | $1M | · | · | · | · | |
| Interest Income | $27M | $42M | $28M | $9M | $466.0K | $2M | $2M | $1M | $477.0K | $504.0K | $542.0K | $568.0K | |
| Other Non-op | $28M | $41M | $31M | $4M | $105.0K | $2M | · | · | · | · | · | · | |
| Pretax Income | $-345M | $-238M | $-183M | $-125M | $-79M | $-29M | $-42M | $-35M | · | · | · | · | |
| Income Tax | $1M | $-4M | $-292.0K | $118.0K | $-6.0K | $-257.0K | $-23.0K | $-24.0K | · | · | · | $0 | |
| Net Income | $-346M | $-234M | $-182M | $-125M | $-79M | $-29M | $-42M | $-34M | $-31M | $-23M | $-16M | $13M | |
| EPS (Basic) | $-4.36 | $-3.01 | $-2.73 | $-2.06 | $-1.77 | $-0.81 | · | $-1.63 | $-1.71 | $-1.48 | $-1.10 | $4.11 | |
| EPS (Diluted) | $-4.36 | $-3.01 | $-2.73 | $-2.06 | $-1.77 | $-0.81 | · | $-1.63 | $-1.72 | $-1.48 | $-1.10 | $3.28 | |
| Shares (Basic) | 79,253,751 | 77,894,643 | 66,889,005 | 60,542,142 | 43,627,452 | 34,542,213 | · | 19,425,711 | 17,985,061 | 15,493,474 | 14,281,837 | 3,165,572 | |
| Shares (Diluted) | 79,253,751 | 77,894,643 | 66,889,005 | 60,542,142 | 43,627,452 | 34,542,213 | · | 19,425,711 | 18,001,759 | 15,493,474 | 14,281,837 | 3,963,797 | |
| EBITDA | $-373M | $-279M | $-214M | $-129M | $-79M | $-31M | $-43M | $-38M | $-33M | $-25M | $-9M | $12M |
Balance general 23
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $199M | $143M | $149M | $57M | $176M | $45M | $25M | $68M | $20M | $17M | $59M | $72M | |
| Short-term Investments | $350M | $484M | $489M | $535M | $376M | $132M | $117M | $52M | $23M | $47M | · | $12M | |
| Receivables | · | $1M | $874.0K | $986.0K | $3M | $2M | $813.0K | $151.0K | $438.0K | $200.0K | $315.0K | $215.0K | |
| Prepaid Expense | $10M | $7M | $6M | $7M | $4M | $3M | $3M | $2M | $716.0K | $1M | $2M | $686.0K | |
| Current Assets | $561M | $635M | $645M | $600M | $559M | $182M | $145M | $121M | $45M | $66M | $61M | $85M | |
| PP&E (Net) | $9M | $10M | $10M | $6M | $4M | $4M | $2M | $991.0K | $1M | $1M | $2M | $2M | |
| Accum. Depreciation | $15M | $13M | $11M | $9M | $13M | $15M | $15M | $16M | $16M | $15M | $15M | $14M | |
| Total Assets | $633M | $798M | $965M | $754M | $572M | $189M | $148M | $122M | $46M | $67M | $64M | $87M | |
| Accounts Payable | $40M | $34M | $26M | $22M | $14M | $11M | $9M | $4M | $3M | $4M | $3M | $3M | |
| Accrued Liabilities | $36M | · | · | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $42M | $36M | $27M | $23M | $14M | $15M | $43M | $4M | $4M | $4M | $3M | $14M | |
| Capital Leases | $6M | $8M | $10M | $10M | $8M | $3M | $743.0K | · | · | · | · | · | |
| Other Non-current Liabilities | $3M | $0 | · | · | · | · | · | · | · | · | · | · | |
| Total Liabilities | $51M | $43M | $37M | $33M | $22M | $18M | $56M | $19M | $10M | $4M | $3M | $15M | |
| Long-term Debt | · | · | · | · | · | · | $16M | · | $7M | · | · | · | |
| Total Debt | · | · | · | · | · | · | $16M | $15M | $7M | · | · | · | |
| Common Stock | $1.60B | $1.46B | $1.44B | $1.07B | $783M | $398M | $294M | $266M | $174M | $173M | $149M | $147M | |
| Paid-in Capital | · | · | · | · | · | · | · | · | · | · | · | $30M | |
| Retained Earnings | $-1.25B | $-899M | $-665M | $-483M | $-357M | $-278M | $-250M | $-208M | $-173M | $-143M | $-120M | $-104M | |
| AOCI | $335.0K | $-2M | $-77.0K | $-3M | $-990.0K | $-990.0K | $-990.0K | $-990.0K | $-990.0K | $-990.0K | $-990.0K | $-990.0K | |
| Stockholders' Equity | $582M | $755M | $928M | $721M | $550M | $171M | $92M | $103M | $36M | $64M | $61M | $73M | |
| Liabilities + Equity | $633M | $798M | $965M | $754M | $572M | $189M | $148M | $122M | $46M | $67M | $64M | $87M | |
| Shares Outstanding | 80,010,790 | 76,416,086 | 75,370,977 | 62,587,701 | 51,634,752 | 35,012,125 | 28,139,228 | 25,750,721 | 17,998,420 | 17,930,590 | 14,385,336 | 14,181,333 |
Flujo de Efectivo 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $3M | $3M | $2M | $1M | $906.0K | $644.0K | $429.0K | $586.0K | $649.0K | $864.0K | $1M | $738.0K | |
| Stock-based Comp | $54M | $51M | $32M | $20M | $10M | $6M | $3M | $3M | $2M | $2M | $4M | $760.0K | |
| Deferred Tax | $-3M | $-9M | $-292.0K | $-44.0K | $58.0K | $-285.0K | $-133.0K | $-105.0K | · | · | · | · | |
| Other Non-cash | · | · | · | · | · | · | · | · | · | · | · | $-14M | |
| Operating Cash Flow | $-279M | $-181M | $-151M | $-101M | $-70M | $-48M | $-5M | $-35M | $-29M | $-20M | $-18M | $266.0K | |
| CapEx | $799.0K | $3M | $6M | $3M | $2M | $3M | $1M | $507.0K | $315.0K | $279.0K | $551.0K | $2M | |
| Investing Cash Flow | $218M | $165M | $-111M | $-293M | $-247M | $-17M | $-66M | $-29M | $24M | · | · | · | |
| Stock Issued | · | · | · | · | · | $102M | $27M | $103M | · | $24M | $278.0K | $43M | |
| Net Stock Activity | · | · | · | · | · | $102M | $27M | $103M | · | $24M | $278.0K | $43M | |
| Financing Cash Flow | $117M | $12M | $354M | $278M | $448M | $86M | $28M | $112M | $7M | · | · | · | |
| Net Change in Cash | $56M | $-6M | $91M | $-118M | $131M | $20M | $-43M | $47M | $3M | $-42M | $-13M | $34M | |
| Taxes Paid | $8M | · | · | · | · | · | · | · | · | · | · | · | |
| Free Cash Flow | $-280M | $-184M | $-151M | $-101M | $-72M | $-51M | $-6M | $-35M | $-29M | $-20M | $-19M | $-1M | |
| Levered FCF | · | · | · | · | · | $-51M | $-7M | · | · | · | · | · |
Rentabilidad 7
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -4974.3% | · | · | -1368.9% | -428.5% | -97.3% | -627.0% | · | -10474.3% | -1376.4% | -60.1% | 39.1% | |
| Net Margin | -4612.1% | · | · | -1329.0% | -427.9% | -89.6% | -609.1% | · | -9872.7% | -1275.5% | -101.1% | 45.9% | |
| Pretax Margin | -4598.6% | · | · | -1327.7% | -427.9% | -90.5% | -609.4% | · | · | · | · | · | |
| EBITDA Margin | -4974.3% | · | · | -1368.9% | -428.5% | -97.3% | -627.0% | · | -10474.3% | -1376.4% | -60.1% | 41.8% | |
| ROA | -48.3% | -26.6% | -21.2% | -18.9% | -20.7% | -17.1% | -30.8% | -40.9% | -54.0% | -35.0% | -20.8% | 18.4% | |
| ROE | -56.9% | -30.2% | -23.3% | -17.0% | -19.8% | -16.3% | -50.0% | -32.2% | -61.5% | -36.8% | -23.5% | -465.5% | |
| ROIC | -64.3% | -36.4% | -23.0% | -17.9% | -14.4% | -18.1% | -39.8% | · | · | · | · | · |
Liquidez y Solvencia 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 13.4 | 17.8 | 23.6 | 26.4 | 39.0 | 12.3 | 3.3 | 29.5 | 11.0 | 18.7 | 21.9 | 5.9 | |
| Quick Ratio | 13.1 | 17.7 | 23.4 | 26.1 | 38.7 | 12.1 | 3.3 | 29.0 | 10.8 | 18.3 | 21.2 | 5.9 | |
| Debt / Equity | · | · | · | · | · | · | 0.2 | 0.1 | 0.2 | · | · | · | |
| LT Debt / Equity | · | · | · | · | · | · | 0.1 | 0.1 | 0.2 | · | · | · | |
| Interest Coverage | · | · | · | · | · | -64.7 | -29.9 | -27.3 | · | · | · | · |
Eficiencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | · | 0.0 | 0.0 | 0.2 | 0.1 | · | 0.0 | 0.0 | 0.2 | 0.4 | |
| Receivables Turnover | · | · | · | 5.0 | 8.0 | 24.4 | 14.2 | · | 1.0 | 7.0 | 58.8 | 86.6 |
Tasas de Crecimiento 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | · | · | · | -48.8% | -42.7% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | -7.4% | · | · | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | -25.3% | · | · | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $8M | $0 | $0 | $9M | $18M | $32M | $7M | $311.0K | $311.0K | $2M | $16M | $28M | |
| Net Income TTM | $-346M | $-234M | $-182M | $-125M | $-79M | $-29M | $-42M | $-34M | $-31M | $-23M | $-16M | $13M | |
| Market Cap | $3.59B | $3.00B | $3.47B | $2.47B | $1.61B | $538M | $369M | $162M | $51M | $138M | $116M | $280M | |
| Enterprise Value | · | · | · | · | · | · | $243M | $58M | $14M | · | · | · | |
| P/E | -10.3 | -13.0 | -16.9 | -19.1 | -17.6 | -19.0 | -7.0 | -3.9 | -1.6 | -5.2 | -7.3 | 6.0 | |
| P/S | 478.1 | · | · | 261.6 | 87.5 | 16.7 | 54.0 | 522.5 | 163.5 | 76.6 | 7.4 | 9.9 | |
| P/B | 6.2 | 4.0 | 3.7 | 3.4 | 2.9 | 3.1 | 4.0 | 1.6 | 1.4 | 2.2 | 1.9 | 3.8 | |
| P / Tangible Book | 6.2 | 4.0 | 3.7 | 3.4 | 2.9 | 3.1 | · | · | · | · | · | · | |
| P / Cash Flow | -12.8 | -16.5 | -23.9 | -25.1 | -23.2 | -11.2 | -79.6 | -4.7 | -1.8 | -7.1 | -6.4 | 1052.9 | |
| P / FCF | -12.8 | -16.2 | -23.0 | -24.4 | -22.5 | -10.6 | -62.8 | -4.6 | -1.8 | -7.0 | -6.2 | -221.8 | |
| EV / EBITDA | · | · | · | · | · | · | -5.7 | -1.5 | -0.4 | · | · | · | |
| EV / FCF | · | · | · | · | · | · | -41.4 | -1.7 | -0.5 | · | · | · | |
| EV / Revenue | · | · | · | · | · | · | 35.6 | 187.1 | 45.0 | · | · | · | |
| Earnings Yield | -9.7% | -7.7% | -5.9% | -5.2% | -5.7% | -5.3% | -14.3% | -25.8% | -60.9% | -19.2% | -13.7% | 16.6% |
Estado de resultados 15
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 | $8M | $0 | $0 | $0 | $0 | · | · | · | · | $0 | $132.0K | |
| R&D Expense | $99M | $89M | $88M | $77M | $75M | $61M | $59M | $57M | $50M | $44M | $41M | $43M | $44M | $40M | $35M | $29M | |
| SG&A Expense | $24M | $24M | $22M | $19M | $19M | $19M | $18M | $17M | $19M | $15M | $13M | $13M | $12M | $10M | $9M | $9M | |
| Operating Expenses | $123M | $112M | $110M | $96M | $94M | $80M | $77M | $74M | $69M | $59M | $54M | $56M | $56M | $49M | $43M | $38M | |
| Operating Income | $-123M | $-112M | $-110M | $-96M | $-94M | $-73M | $-77M | $-74M | $-69M | $-59M | $-54M | $-56M | $-56M | $-49M | $-43M | $-38M | |
| Interest Income | $12M | $7M | $5M | $6M | $7M | $8M | $9M | $10M | $11M | $11M | $9M | $7M | $7M | $5M | $4M | $3M | |
| Other Non-op | $12M | $7M | $5M | $6M | $9M | $8M | $8M | $11M | $11M | $12M | $9M | $7M | $8M | $8M | $7M | $391.0K | |
| Pretax Income | $-111M | $-105M | $-105M | $-90M | $-85M | $-65M | $-70M | $-63M | $-58M | $-48M | $-45M | $-49M | $-48M | $-41M | $-36M | $-38M | |
| Income Tax | $-585.0K | $-3M | $538.0K | $677.0K | $-626.0K | $427.0K | $-4M | $-320.0K | $-333.0K | $412.0K | $-205.0K | $-157.0K | $-220.0K | $290.0K | $1M | $-587.0K | |
| Net Income | $-111M | $-102M | $-105M | $-91M | $-85M | $-65M | $-66M | $-63M | $-58M | $-48M | $-45M | $-48M | $-47M | $-42M | $-37M | $-37M | |
| EPS (Basic) | $-1.11 | $-1.17 | $-1.31 | $-1.15 | $-1.07 | $-0.83 | $-0.83 | $-0.81 | $-0.75 | $-0.62 | $-0.65 | $-0.73 | $-0.72 | $-0.63 | $-0.59 | $-0.57 | |
| EPS (Diluted) | $-1.11 | $-1.17 | $-1.31 | $-1.15 | $-1.07 | $-0.83 | $-0.83 | $-0.81 | $-0.75 | $-0.62 | $-0.65 | $-0.73 | $-0.72 | $-0.63 | $-0.59 | $-0.57 | |
| Shares (Basic) | 99,609,804 | 87,345,717 | -157,635,173 | 79,247,976 | 78,953,445 | 78,687,503 | -155,297,289 | 77,926,205 | 77,671,128 | 77,594,599 | -130,698,977 | 66,002,163 | 65,861,138 | 65,724,681 | -115,968,641 | 65,465,069 | |
| Shares (Diluted) | 99,609,804 | 87,345,717 | -157,635,173 | 79,247,976 | 78,953,445 | 78,687,503 | -155,297,289 | 77,926,205 | 77,671,128 | 77,594,599 | -130,698,977 | 66,002,163 | 65,861,138 | 65,724,681 | -115,968,641 | 65,465,069 | |
| EBITDA | $-123M | $-112M | · | $-96M | $-94M | $-73M | · | $-74M | $-69M | $-59M | · | $-56M | $-56M | $-49M | · | $-38M |
Balance general 20
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $120M | $546M | $199M | $105M | $135M | $117M | $143M | $88M | $137M | $59M | · | $100M | $65M | $70M | · | $103M | |
| Short-term Investments | $811M | $549M | $350M | $358M | $352M | $433M | $484M | $566M | $585M | $641M | · | $427M | $475M | $458M | · | $535M | |
| Receivables | · | · | · | · | · | · | · | $938.0K | $853.0K | $833.0K | · | $805.0K | $2M | $2M | · | $2M | |
| Prepaid Expense | $14M | $11M | $10M | $17M | $12M | $7M | $7M | $5M | $6M | $7M | · | $4M | $3M | $4M | · | $9M | |
| Current Assets | $946M | $1.11B | $561M | $480M | $500M | $566M | $635M | $660M | $728M | $707M | · | $531M | $545M | $533M | · | $649M | |
| PP&E (Net) | $8M | $8M | $9M | $9M | $9M | $10M | $10M | $10M | $10M | $9M | · | $10M | $10M | $8M | · | $5M | |
| Accum. Depreciation | · | · | $15M | · | · | · | $13M | · | · | · | · | · | · | · | · | · | |
| Total Assets | $1.30B | $1.39B | $633M | $608M | $674M | $743M | $798M | $836M | $884M | $919M | · | $671M | $685M | $720M | · | $776M | |
| Accounts Payable | $44M | $38M | $40M | $37M | $32M | $31M | $34M | $28M | $30M | $21M | · | $23M | $27M | $21M | · | $16M | |
| Accrued Liabilities | $41M | $33M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $45M | $40M | $42M | $38M | $33M | $32M | $36M | $30M | $31M | $22M | · | $25M | $28M | $22M | · | $16M | |
| Capital Leases | $5M | $6M | $6M | $7M | $7M | $7M | $8M | $8M | $9M | $9M | · | $10M | $10M | $10M | · | $7M | |
| Other Non-current Liabilities | $3M | $3M | $3M | $3M | · | · | $0 | · | · | · | · | · | · | · | · | · | |
| Total Liabilities | $53M | $49M | $51M | $48M | $40M | $39M | $43M | $38M | $40M | $31M | · | $35M | $38M | $33M | · | $23M | |
| Common Stock | $2.43B | $2.42B | $1.60B | $1.48B | $1.47B | $1.46B | $1.46B | $1.44B | $1.44B | $1.44B | · | $1.12B | $1.08B | $1.07B | · | $1.06B | |
| Retained Earnings | $-1.46B | $-1.35B | $-1.25B | $-1.14B | $-1.05B | $-965M | $-899M | $-834M | $-771M | $-713M | · | $-620M | $-572M | $-524M | · | $-445M | |
| AOCI | $-3M | $-1M | $335.0K | $477.0K | $113.0K | $-836.0K | $-2M | $1M | $-2M | $-2M | · | $-3M | $-3M | $-2M | · | $-3M | |
| Stockholders' Equity | $1.24B | $1.34B | $582M | $560M | $634M | $704M | $755M | $798M | $844M | $888M | $928M | $637M | $646M | $687M | $721M | $753M | |
| Liabilities + Equity | $1.30B | $1.39B | $633M | $608M | $674M | $743M | $798M | $836M | $884M | $919M | · | $671M | $685M | $720M | · | $776M | |
| Shares Outstanding | 96,752,884 | 96,624,123 | 80,010,790 | 77,120,168 | 76,939,811 | 76,586,359 | 76,416,086 | 75,794,409 | 75,667,550 | 75,459,681 | · | 65,002,249 | 63,718,350 | 63,107,020 | · | 62,542,542 |
Flujo de Efectivo 9
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $558.0K | $587.0K | $611.0K | $641.0K | $632.0K | $659.0K | $666.0K | $636.0K | $628.0K | $586.0K | $-629.0K | $2M | $602.0K | $354.0K | $296.0K | $358.0K | |
| Stock-based Comp | $17M | $17M | $14M | $14M | $14M | $12M | $14M | $13M | $15M | $9M | $9M | $9M | $8M | $6M | $6M | $6M | |
| Deferred Tax | $-2M | $447.0K | $-1M | $-701.0K | $-170.0K | $-1M | $-9M | $-322.0K | $-333.0K | $403.0K | $-200.0K | $-156.0K | $-224.0K | $288.0K | $5.0K | $-203.0K | |
| Operating Cash Flow | $-95M | $-89M | $-81M | $-72M | $-64M | $-62M | $-54M | $-51M | $-34M | $-46M | $-35M | $-48M | $-33M | $-34M | $-35M | $-30M | |
| CapEx | $275.0K | $133.0K | $318.0K | $281.0K | $157.0K | $43.0K | $783.0K | $590.0K | $2M | $188.0K | $78.0K | $1M | $2M | $2M | $2M | $386.0K | |
| Investing Cash Flow | $-331M | $-407M | $63M | $39M | $82M | $35M | $99M | $2M | $112M | $-43M | $-240M | $54M | $28M | $47M | $-12M | $-234M | |
| Financing Cash Flow | $26.0K | $843M | $114M | $2M | $65.0K | $1M | $12M | $0 | $0 | $0 | $324M | · | · | · | $6.0K | $699.0K | |
| Net Change in Cash | $-426M | $347M | $95M | $-31M | $19M | $-26M | $55M | $-49M | $78M | $-90M | $49M | $35M | $-5M | $12M | $-46M | $-266M | |
| Free Cash Flow | · | $-89M | · | · | · | $-62M | · | · | · | $-43M | · | · | · | $-37M | · | · |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | -969.8% | · | · | · | · | · | · | · | · | · | -28884.8% | |
| Net Margin | · | · | · | · | · | -867.3% | · | · | · | · | · | · | · | · | · | -28143.9% | |
| Pretax Margin | · | · | · | · | · | -861.6% | · | · | · | · | · | · | · | · | · | -28588.6% | |
| EBITDA Margin | · | · | · | · | · | -969.8% | · | · | · | · | · | · | · | · | · | -28884.8% | |
| ROA | -11.2% | -9.6% | · | -12.6% | -10.9% | -7.8% | · | -8.3% | -7.4% | -5.9% | · | -6.7% | -6.4% | -6.5% | · | -7.1% | |
| ROE | -11.8% | -10.0% | · | -13.4% | -11.5% | -8.2% | · | -8.8% | -7.8% | -6.1% | · | -7.0% | -6.6% | -6.8% | · | -7.4% | |
| ROIC | -9.9% | -8.2% | · | -17.3% | -14.8% | -10.4% | · | -9.2% | -8.1% | -6.7% | · | -8.7% | -8.6% | -7.2% | · | -5.0% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 21.0 | 27.8 | · | 12.5 | 15.1 | 17.7 | · | 22.2 | 23.3 | 31.8 | · | 21.5 | 19.3 | 23.7 | · | 41.8 | |
| Quick Ratio | 20.7 | 27.5 | · | 12.1 | 14.8 | 17.2 | · | 22.1 | 23.1 | 31.5 | · | 21.3 | 19.2 | 23.5 | · | 41.2 |
Eficiencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · | · | · | · | · | · | · | · | 0.0 | |
| Receivables Turnover | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.0 |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $8M | · | $8M | $8M | $8M | · | · | · | · | · | $18M | $18M | $18M | · | $18M | |
| Net Income TTM | $-389M | $-343M | · | $-303M | $-270M | $-234M | · | $-217M | $-202M | $-186M | · | $-175M | $-157M | $-130M | · | $-103M | |
| Market Cap | $5.84B | $5.62B | · | $3.10B | $2.41B | $2.57B | · | $2.98B | $2.95B | $3.25B | · | $2.22B | $2.45B | $2.26B | · | $2.26B | |
| P/E | -13.4 | -13.8 | · | -10.4 | -9.0 | -11.1 | · | -13.5 | -13.8 | -15.9 | · | -12.9 | -15.6 | -17.0 | · | -19.7 | |
| P/S | · | 749.2 | · | 412.9 | 321.1 | 342.6 | · | · | · | · | · | 126.5 | 139.7 | 128.6 | · | 128.6 | |
| P/B | 4.7 | 4.2 | · | 5.5 | 3.8 | 3.6 | · | 3.7 | 3.5 | 3.7 | · | 3.5 | 3.8 | 3.3 | · | 3.0 | |
| P / Tangible Book | 4.7 | 4.2 | · | 5.5 | 3.8 | 3.6 | · | 3.7 | 3.5 | 3.7 | · | 3.5 | 3.8 | 3.3 | · | 3.0 | |
| P / Cash Flow | · | -63.2 | · | · | · | -41.7 | · | · | · | -75.2 | · | · | · | -65.6 | · | · | |
| P / FCF | · | -63.1 | · | · | · | -41.6 | · | · | · | -74.9 | · | · | · | -61.7 | · | · | |
| Earnings Yield | -7.5% | -7.3% | · | -9.6% | -11.1% | -9.0% | · | -7.4% | -7.2% | -6.3% | · | -7.8% | -6.4% | -5.9% | · | -5.1% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $8M | $0 | $0 | $9M | $18M |
| Margen Operativo % | -4974.3% | — | — | -1368.9% | -428.5% |
| Beneficio neto | $-346M | $-234M | $-182M | $-125M | $-79M |
| EPS Diluido | $-4.36 | $-3.01 | $-2.73 | $-2.06 | $-1.77 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 13.4 | 17.8 | 23.6 | 26.4 | 39.0 |
| Ratio Rápido | 13.1 | 17.7 | 23.4 | 26.1 | 38.7 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-280M | $-184M | $-151M | $-101M | $-72M |
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Propietarios institucionales (13F) 334 declarantes · $4.2B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 58 (-17 vs trimestre anterior) | 22 (-10 vs trimestre anterior) | 113 (-7 vs trimestre anterior) | 87 (+22 vs trimestre anterior) | -3.8M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| FMR LLC | $413 296 388 | 6 847 190 | 9,78% | Acciones |
| Avoro Capital Advisors LLC | $348 746 620 | 5 777 777 | 8,25% | Acciones |
| Polar Capital Holdings Plc | $275 878 760 | 4 570 556 | 6,53% | Acciones |
| Driehaus Capital Management LLC | $266 704 101 | 4 418 557 | 6,31% | Acciones |
| Capital International Investors | $142 548 530 | 2 361 639 | 3,37% | Acciones |
| STATE STREET CORP | $118 885 244 | 1 969 629 | 2,81% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $99 162 305 | 1 642 848 | 2,35% | Acciones |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $97 523 411 | 1 615 696 | 2,31% | Acciones |
| Affinity Asset Advisors, LLC | $96 274 200 | 1 595 000 | 2,28% | Acciones |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $90 980 266 | 1 507 294 | 2,15% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $90 846 349 | 1 562 276 | 2,15% | Acciones |
| Siren, L.L.C. | $79 588 523 | 1 318 564 | 1,88% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $74 162 795 | 1 228 797 | 1,75% | Acciones |
| Pictet Asset Management Holding SA | $71 645 411 | 1 187 723 | 1,70% | Acciones |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $69 677 471 | 1 154 365 | 1,65% | Acciones |
| BRAIDWELL LP | $68 294 443 | 1 131 452 | 1,62% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $61 270 953 | 1 015 092 | 1,45% | Acciones |
| CITADEL ADVISORS LLC | $60 749 141 | 1 006 447 | 1,44% | Acciones |
| ORBIMED ADVISORS LLC | $53 869 550 | 892 471 | 1,27% | Acciones |
| Caligan Partners LP | $53 717 020 | 889 944 | 1,27% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $53 377 571 | 884 319 | 1,26% | Acciones |
| FEDERATED HERMES, INC. | $53 342 365 | 883 737 | 1,26% | Acciones |
| Capital World Investors | $52 077 099 | 862 775 | 1,23% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $45 248 934 | 749 651 | 1,07% | Acciones |
| Caption Management, LLC | $43 942 080 | 728 000 | 1,04% | Opción de compra |
| Vestal Point Capital, LP | $42 252 000 | 700 000 | 1,00% | Acciones |
| Alyeska Investment Group, L.P. | $42 112 689 | 697 692 | 1,00% | Acciones |
| Rock Springs Capital Management LP | $41 280 627 | 683 907 | 0,98% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $40 080 911 | 664 031 | 0,95% | Acciones |
| First Turn Management, LLC | $36 228 072 | 600 200 | 0,86% | Acciones |
| TUDOR INVESTMENT CORP ET AL | $32 919 559 | 545 387 | 0,78% | Acciones |
| Octagon Capital Advisors LP | $29 576 400 | 490 000 | 0,70% | Acciones |
| NOVO HOLDINGS A/S | $29 301 038 | 485 438 | 0,69% | Acciones |
| Candriam S.C.A. | $27 905 802 | 462 768 | 0,66% | Acciones |
| Logos Global Management LP | $27 162 000 | 450 000 | 0,64% | Acciones |
| Trails Edge Capital Partners, LP | $26 558 400 | 440 000 | 0,63% | Acciones |
| LOOMIS SAYLES & CO L P | $26 465 868 | 438 467 | 0,63% | Acciones |
| ALGERT GLOBAL LLC | $25 337 498 | 419 773 | 0,60% | Acciones |
| Aberdeen Group plc | $24 671 305 | 408 736 | 0,58% | Acciones |
| Parkman Healthcare Partners LLC | $23 985 796 | 397 379 | 0,57% | Acciones |
| Fiera Capital Corp | $23 968 111 | 397 086 | 0,57% | Acciones |
| Nicholas Investment Partners, LP | $23 893 144 | 395 844 | 0,57% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $22 742 260 | 376 777 | 0,54% | Acciones |
| BAKER BROS. ADVISORS LP | $22 345 755 | 370 208 | 0,53% | Acciones |
| Jones Hill Capital LP | $22 206 444 | 367 900 | 0,53% | Acciones |
| GOLDMAN SACHS GROUP INC | $21 955 648 | 363 745 | 0,52% | Acciones |
| TimesSquare Capital Management, LLC | $20 892 888 | 359 293 | 0,49% | Acciones |
| AMERIPRISE FINANCIAL INC | $18 371 048 | 304 358 | 0,43% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $18 108 000 | 300 000 | 0,43% | Acciones |
| Soleus Capital Management, L.P. | $16 116 120 | 267 000 | 0,38% | Acciones |
| DAFNA Capital Management LLC | $15 136 598 | 250 772 | 0,36% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $15 058 190 | 249 473 | 0,36% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $15 018 836 | 248 821 | 0,36% | Acciones |
| NAN FUNG TRINITY (HK) LTD | $14 955 095 | 247 765 | 0,35% | Acciones |
| Redmile Group, LLC | $13 845 015 | 229 374 | 0,33% | Acciones |
| Schonfeld Strategic Advisors LLC | $13 721 637 | 227 330 | 0,32% | Acciones |
| D. E. Shaw & Co., Inc. | $13 515 932 | 223 922 | 0,32% | Acciones |
| Patient Square Capital LP | $13 279 200 | 220 000 | 0,31% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $12 704 030 | 210 471 | 0,30% | Acciones |
| JENNISON ASSOCIATES LLC | $12 558 501 | 208 060 | 0,30% | Acciones |
| Trexquant Investment LP | $12 220 184 | 202 455 | 0,29% | Acciones |
| DNB Asset Management AS | $12 099 222 | 200 451 | 0,29% | Acciones |
| Integral Health Asset Management, LLC | $12 072 000 | 200 000 | 0,29% | Acciones |
| Eversept Partners, LP | $11 862 672 | 196 532 | 0,28% | Acciones |
| Balyasny Asset Management L.P. | $11 671 391 | 193 363 | 0,28% | Acciones |
| TWO SIGMA ADVISERS, LP | $11 622 722 | 259 320 | 0,28% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $11 438 220 | 189 500 | 0,27% | Opción de compra |
| RENAISSANCE TECHNOLOGIES LLC | $11 293 960 | 187 110 | 0,27% | Acciones |
| SILVERARC CAPITAL MANAGEMENT, LLC | $11 276 516 | 186 821 | 0,27% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $11 066 583 | 183 343 | 0,26% | Acciones |
| NEXTBio Capital Management LP | $11 059 461 | 183 225 | 0,26% | Acciones |
| Iron Triangle Partners LP | $10 473 896 | 233 688 | 0,25% | Acciones |
| ADAR1 Capital Management, LLC | $10 052 958 | 166 550 | 0,24% | Acciones |
| PEREGRINE CAPITAL MANAGEMENT LLC | $9 953 002 | 164 894 | 0,24% | Acciones |
| Swiss National Bank | $9 820 572 | 162 700 | 0,23% | Acciones |
| Foresite Capital Management IV, LLC | $9 657 600 | 160 000 | 0,23% | Acciones |
| Woodline Partners LP | $9 374 029 | 155 302 | 0,22% | Acciones |
| BANK OF AMERICA CORP /DE/ | $9 207 133 | 152 537 | 0,22% | Acciones |
| BlackRock, Inc. | $8 785 700 | 145 555 | 0,21% | Acciones |
| NEUBERGER BERMAN GROUP LLC | $8 336 802 | 138 118 | 0,20% | Acciones |
| Susquehanna Portfolio Strategies, LLC | $8 031 441 | 133 059 | 0,19% | Acciones |
| Point72 Asset Management, L.P. | $7 869 616 | 130 378 | 0,19% | Acciones |
| Granahan Investment Management, LLC | $7 813 179 | 129 443 | 0,18% | Acciones |
| RHUMBLINE ADVISERS | $7 448 289 | 123 398 | 0,18% | Acciones |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $7 294 370 | 121 310 | 0,17% | Acciones |
| AXA Investment Managers S.A. | $7 072 704 | 176 157 | 0,17% | Acciones |
| Squarepoint Ops LLC | $6 812 773 | 112 869 | 0,16% | Acciones |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $6 615 637 | 109 603 | 0,16% | Acciones |
| AXIOM INVESTORS LLC /DE | $6 533 246 | 108 238 | 0,15% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $6 337 800 | 105 000 | 0,15% | Acciones |
| Burkehill Global Management, LP | $6 036 000 | 100 000 | 0,14% | Acciones |
| ALPS ADVISORS INC | $5 891 740 | 97 610 | 0,14% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $5 606 116 | 92 878 | 0,13% | Acciones |
| Bank of New York Mellon Corp | $5 469 280 | 90 611 | 0,13% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $5 393 238 | 92 747 | 0,13% | Acciones |
| ExodusPoint Capital Management, LP | $5 105 913 | 84 591 | 0,12% | Acciones |
| CAPITAL FUND MANAGEMENT S.A. | $5 098 609 | 84 470 | 0,12% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $4 955 556 | 82 100 | 0,12% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $4 694 197 | 77 770 | 0,11% | Acciones |
| Walleye Capital LLC | $4 645 004 | 76 955 | 0,11% | Acciones |
Informantes de la empresa 32 insiders · 15 directivos · 16 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Ian Mortimer | PRESIDENT & CEO | 12 de marzo de 2026 M | 19 923 | 0 | 18 | $-21 298 042 |
| Thomas Patrick Kelly | Chief Financial Officer | 15 de octubre de 2025 A | — | 0 | 0 | $0 |
| Sherry Aulin | Chief Financial Officer | 18 de diciembre de 2024 M | 0 | 0 | 0 | $0 |
| Christopher John Kenney | Chief Medical Officer | 12 de marzo de 2026 M | 7 069 | 0 | 2 | $-244 425 |
| Andrea Difabio | Chief Legal Officer | 12 de marzo de 2026 M | 7 301 | 0 | 2 | $-230 812 |
| Darren S Cline | Chief Commercial Officer | 9 de enero de 2026 A | — | 0 | 0 | $0 |
| Christopher Von Seggern | Chief Commercial Officer | 11 de marzo de 2024 A | 4 000 | 0 | 0 | $0 |
| James R. Empfield | EVP, Drug Discovery | 11 de marzo de 2024 A | 10 000 | 0 | 0 | $0 |
| Sherrington Robin | EVP, Strategy & Innovation | 11 de marzo de 2024 A | 8 398 | 0 | 0 | $0 |
| Ernesto Aycardi-Fonseca | CMO | 12 de marzo de 2020 A | — | 0 | 0 | $0 |
| Charles J. Cohen | VP, Biology | 11 de diciembre de 2018 M | 6 550 | 0 | 0 | $0 |
| Paul Y. Goldberg | SVP, Clinical Development | 23 de octubre de 2017 A | 6 000 | 0 | 0 | $0 |
| Raymond Winquist | Head, Translational Research | 18 de agosto de 2017 P | 1 000 | 0 | 0 | $0 |
| Karen G. Corraini | Gen. Counsel & Corp. Secretary | 17 de marzo de 2015 A | — | 0 | 0 | $0 |
| Gary Bridger | EVP, Research & Development | 21 de noviembre de 2014 A | — | 0 | 0 | $0 |
| Gillian Cannon | Consejero | 5 de junio de 2026 S | 1 455 | 0 | 1 | $-63 237 |
| Gary Patou | Consejero | 5 de junio de 2026 S | 24 896 | 0 | 1 | $-70 251 |
| Elizabeth A. Garofalo | Consejero | 3 de junio de 2026 A | 2 645 | 0 | 0 | $0 |
| Justin D. Gover | Consejero | 3 de junio de 2026 A | 2 645 | 0 | 0 | $0 |
| Dawn Svoronos | Consejero | 3 de junio de 2026 A | 26 229 | 0 | 0 | $0 |
| Patrick Machado | Consejero | 3 de junio de 2026 A | 2 645 | 0 | 0 | $0 |
| Mohammad Azab | Consejero | 19 de diciembre de 2023 M | 74 225 | 0 | 0 | $0 |
| Simon N. Pimstone | Consejero | 2 de junio de 2023 A | 6 000 | 0 | 0 | $0 |
| Michael R Hayden | Consejero | 3 de junio de 2021 A | 116 206 | 0 | 0 | $0 |
| Frank A Holler | Consejero | 27 de mayo de 2021 M | 143 653 | 0 | 0 | $0 |
| Michael M Tarnow | Consejero | 18 de mayo de 2021 M | 77 942 | 0 | 0 | $0 |
| Clarissa Desjardins | Consejero | 1 de junio de 2020 A | — | 0 | 0 | $0 |
| Richard H Scheller | Consejero | 16 de septiembre de 2019 A | 7 000 | 0 | 0 | $0 |
| Johnston L Evans | Consejero | 4 de mayo de 2015 A | 444 655 | 0 | 0 | $0 |
| Evan A. Stein | Consejero | 30 de abril de 2015 J | 4 172 | 0 | 0 | $0 |
| Associates, Llp Mx | Propietario del 10% | 9 de noviembre de 2014 C | 1 474 660 | 0 | 0 | $0 |
| Steven Gannon | — | 11 de agosto de 2026 S | 1 870 | 0 | 1 | $-640 600 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Propiedad de ETFs Mantenido por 41 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| IBRN · iShares Trust | 4,76% | 5 685 SH | 8 de agosto de 2026 | Diario |
| SBIO · ALPS ETF Trust | 2,90% | 85 746 NS | 31 de mayo de 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 1,92% | 14 366 NS | 31 de mayo de 2026 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 1,35% | 4 977 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,94% | 6 264 NS | 30 de abril de 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,88% | 8 393 NS | 31 de mayo de 2026 | N-PORT |
| GSC · Goldman Sachs ETF Trust | 0,74% | 34 036 NS | 31 de mayo de 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,72% | 6 855 NS | 31 de mayo de 2026 | N-PORT |
| SMMV · iShares Trust | 0,59% | 26 652 SH | 8 de agosto de 2026 | Diario |
| MEDI · Harbor ETF Trust | 0,50% | 2 438 NS | 30 de abril de 2026 | N-PORT |
| IBB · iShares Trust | 0,45% | 665 671 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,42% | 5 259 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,39% | 889 435 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,35% | 104 976 SH | 8 de agosto de 2026 | Diario |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0,27% | 535 NS | 30 de abril de 2026 | N-PORT |
| NUSC · Nushares ETF Trust | 0,26% | 60 188 NS | 30 de abril de 2026 | N-PORT |
| BIB · ProShares Trust | 0,23% | 3 074 NS | 31 de mayo de 2026 | N-PORT |
| IWM · iShares Trust | 0,20% | 2 483 574 SH | 8 de agosto de 2026 | Diario |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,19% | 26 381 NS | 31 de mayo de 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,18% | 564 724 SH | 8 de agosto de 2026 | Diario |
| ESLG · Strategy Shares | 0,16% | 565 NS | 30 de abril de 2026 | N-PORT |
| RSSL · Global X Funds | 0,15% | 37 381 NS | 30 de abril de 2026 | N-PORT |
| ESML · iShares Trust | 0,14% | 61 538 SH | 8 de agosto de 2026 | Diario |
| ITWO · ProShares Trust | 0,12% | 4 067 NS | 31 de mayo de 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,11% | 24 922 NS | 30 de abril de 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,09% | 3 887 SH | 8 de agosto de 2026 | Diario |
| FHLC · FIDELITY COVINGTON TRUST | 0,07% | 36 576 NS | 30 de abril de 2026 | N-PORT |
| UWM · ProShares Trust | 0,07% | 3 181 NS | 31 de mayo de 2026 | N-PORT |
| AVIE · AMERICAN CENTURY ETF TRUST | 0,05% | 101 NS | 31 de mayo de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,05% | 9 276 NS | 31 de mayo de 2026 | N-PORT |
| URTY · ProShares Trust | 0,05% | 3 221 NS | 31 de mayo de 2026 | N-PORT |
| PDN · Invesco Exchange-Traded Fund Trust … | 0,05% | 2 770 SH | 8 de agosto de 2026 | Diario |
| WSML · iShares Trust | 0,05% | 4 847 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,04% | 14 319 SH | 8 de agosto de 2026 | Diario |
| HDG · ProShares Trust | 0,02% | 81 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 23 963 NS | 31 de mayo de 2026 | N-PORT |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,01% | 8 110 SH | 8 de agosto de 2026 | Diario |
| ESGV · VANGUARD WORLD FUND | 0,01% | 21 635 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,01% | 26 801 SH | 8 de agosto de 2026 | Diario |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 1 120 NS | 31 de mayo de 2026 | N-PORT |
| VT · VANGUARD INTERNATIONAL EQUITY INDEX… | 0,00% | 77 770 SH | 8 de agosto de 2026 | Diario |