ZYME Zymeworks Inc. - Common Stock
Acerca de Zymeworks Inc. - Common Stock Descripción general de la empresa de Wikipedia
Zymeworks Inc. is a publicly held biotechnology company based in Vancouver, British Columbia, that develops protein therapeutics for the treatment of cancer as well as for autoimmune and inflammatory diseases. The products are based upon the company's molecular modeling software for optimizing protein structure. In 2014, Zymeworks raised $44 million across various funding rounds according to PitchBook, placing it among the top 10 HealthTech businesses in the world to raise the most capital that year. In May 2017, Zymeworks held an IPO on the Toronto Stock Exchange, raising $59 million. This was the largest Canadian biotech IPO in more than a decade. By alphabetical order, Zymeworks is the last company on the Toronto Stock Exchange.
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Zymeworks Inc. is a publicly held biotechnology company based in Vancouver,
British Columbia, that develops protein therapeutics for the treatment of cancer as well as for autoimmune and inflammatory diseases. The products are based upon the company's molecular modeling software for optimizing protein structure. In 2014, Zymeworks raised $44 million across various funding rounds according to PitchBook, placing it among the top 10 HealthTech businesses in the world to raise the most capital that year. In May 2017, Zymeworks held an IPO on the Toronto Stock Exchange, raising $59 million. This was the largest Canadian biotech IPO in more than a decade. By alphabetical order, Zymeworks is the last company on the Toronto Stock Exchange.
In May 2019, Zymeworks announced that GSK has expanded its 2016 licensing and collaboration agreement for the research, development and commercialization of bispecific antibodies across multiple disease areas. The extended agreement has meant that GSK can have access to Zymeworks' heavy-light chain pairing technology, which enables the development of bispecific and multifunctional therapeutics.
In September 2019, Zymeworks announced that, following their clinical trials, it has been confirmed that their ZW25 monotherapy can provide durable disease control in patients with a variety of HER2-expressing solid tumors that have progressed following standard of care treatments.
In May 2022, Zymeworks rejected an unsolicited takeover proposal from a Dubai hedge fund, All Blue Falcons FZE, an arm of All Blue Capital.
Azymetric
This is an IgG1-based heterodimeric antibody scaffold that consists of two different heavy chains engineered to exclusively assemble into a single molecule, allowing bi-specific binding to two different antigens or drug targets. The Azymetric scaffold is engineered by making amino acid changes in the CH3 region of the constant Fc domain of the IgG1. This scaffold can also be engineered with tailored effector function and optimized serum half-life.
Awards and recognition
Deal of the Year, Lifesciences BC Awards, 2018
Life Sciences Company of the Year, Lifesciences BC Awards, 2016
Emerging company of the year – Health, BIOTECanada Gold Leaf Awards, 2015
12th Place, BC's Leading Innovators, 2011
Life Science Emerging Rocket, 2009, 2010, 2011
Early stage Company of the year – Industrial & Agriculture, BIOTECanada Gold Leaf Awards, 2009
== References ==
Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗
ZYME Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
ZYME Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
ZYME Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 6 33,3%
- Compra 11 61,1%
- Mantener 1 5,6%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
12 analistas · 2026-08-16Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.62 | $-0.50 | -0.12% |
| 31 de marzo de 2026 | $-0.59 | $-0.20 | -0.39% |
| 31 de diciembre de 2025 | $-0.55 | $-0.42 | -0.13% |
| 30 de septiembre de 2025 | $-0.26 | $-0.33 | 0.07% |
| 30 de junio de 2025 | $0.03 | $-0.50 | 0.53% |
| 31 de marzo de 2025 | $-0.30 | $-0.42 | 0.12% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
| AUPH | $2.11B | 7.7 | 20.4% | 101.5% | 62.7% | — |
| ABUS | $926M | -28.3 | 128.2% | -237.9% | -42.0% | — |
| ACOG | $141M | -5.5 | — | -202.2% | -43.8% | — |
| PMN | $15M | -0.3 | — | — | 4840.3% | — |
| XENE | $3.59B | -10.3 | — | -4612.1% | -56.9% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue | $106M | $76M | $76M | $412M | $27M | |
| R&D Expense | · | · | $144M | $209M | $200M | |
| SG&A Expense | $62M | $62M | $70M | $73M | $43M | |
| Operating Expenses | $199M | $213M | $214M | $282M | $242M | |
| Operating Income | $-93M | $-137M | $-138M | $131M | $-216M | |
| Other Non-op | $51.0K | $-218.0K | $291.0K | $-42.0K | $118.0K | |
| Pretax Income | $-80M | $-117M | $-119M | $135M | $-212M | |
| Income Tax | $1M | $6M | $-568.0K | $11M | $-516.0K | |
| Net Income | $-81M | $-123M | $-119M | $124M | $-212M | |
| EPS (Basic) | $-1.08 | $-1.62 | $-1.72 | $1.91 | $-4.11 | |
| EPS (Diluted) | $-1.08 | $-1.62 | $-1.72 | $1.90 | $-4.61 | |
| Shares (Basic) | 75,404,897 | 75,846,681 | 68,863,010 | 65,194,775 | 51,553,869 | |
| Shares (Diluted) | 75,413,396 | 75,878,738 | 68,863,010 | 65,249,184 | 52,131,596 | |
| EBITDA | $-93M | $-137M | $-138M | · | · |
Balance general 23
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Cash & Equivalents | $41M | $66M | $158M | $401M | $202M | |
| Short-term Investments | · | · | $217M | $91M | $51M | |
| Receivables | $5M | $56M | $19M | $33M | $16M | |
| Prepaid Expense | $15M | $19M | $19M | $19M | $20M | |
| Current Assets | $249M | $300M | $413M | $545M | $288M | |
| PP&E (Net) | $16M | $18M | $20M | $25M | $23M | |
| PP&E (Gross) | $36M | $35M | $41M | $38M | $37M | |
| Accum. Depreciation | $21M | $18M | $21M | $13M | $14M | |
| Goodwill | $12M | $12M | $12M | $12M | $12M | |
| Intangibles | $1M | $5M | $8M | $9M | $4M | |
| Total Assets | $347M | $463M | $581M | $649M | $389M | |
| Accounts Payable | $36M | $60M | $46M | $87M | $63M | |
| Current Liabilities | $42M | $88M | $56M | $96M | $72M | |
| Capital Leases | $15M | $16M | $22M | $25M | $31M | |
| Deferred Tax | $6M | $5M | $3M | $2M | $2M | |
| Other Non-current Liabilities | $278.0K | $923.0K | $2M | $3M | $3M | |
| Total Liabilities | $78M | $124M | $116M | $156M | $140M | |
| Common Stock | $1.11B | $1.02B | $997M | $886M | $741M | |
| Retained Earnings | $-953M | $-830M | $-677M | $-559M | $-683M | |
| AOCI | $-6M | $-7M | $-7M | $-7M | $-7M | |
| Stockholders' Equity | $269M | $339M | $465M | $493M | $249M | |
| Liabilities + Equity | $347M | $463M | $581M | $649M | $389M | |
| Shares Outstanding | 74,638,413 | 68,964,319 | 70,115,997 | 63,059,501 | 46,633,935 |
Flujo de Efectivo 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Stock-based Comp | $28M | $18M | $8M | $4M | $11M | |
| Deferred Tax | $945.0K | $691.0K | $-757.0K | $2M | $-953.0K | |
| Amort. of Intangibles | $4M | $4M | $3M | $1M | $3M | |
| Restructuring | · | · | $0 | · | · | |
| Operating Cash Flow | $-33M | $-110M | $-118M | $144M | $-192M | |
| CapEx | $2M | $2M | $2M | $8M | $12M | |
| Investing Cash Flow | $27M | $39M | $-207M | $-54M | $145M | |
| Stock Issued | $0 | $0 | $26M | $108M | $0 | |
| Stock Repurchased | $42M | $30M | $0 | $0 | · | |
| Net Stock Activity | $-42M | $-30M | $26M | · | · | |
| Financing Cash Flow | $-19M | $-20M | $82M | $109M | $8M | |
| Net Change in Cash | $-25M | $-91M | $-243M | $199M | $-40M | |
| Taxes Paid | $1M | $3M | $165.0K | $10M | · | |
| Free Cash Flow | $-35M | $-112M | $-121M | · | · |
Rentabilidad 7
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Operating Margin | -87.3% | -179.7% | -181.6% | · | · | |
| Net Margin | -76.6% | -160.8% | -156.1% | · | · | |
| Pretax Margin | -75.3% | -152.8% | -156.9% | · | · | |
| EBITDA Margin | -87.3% | -179.7% | -181.6% | · | · | |
| ROA | -20.0% | -23.5% | -19.3% | · | · | |
| ROE | -26.9% | -34.8% | -26.7% | · | · | |
| ROIC | -35.1% | -42.6% | -29.6% | · | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Current Ratio | 5.9 | 3.4 | 7.4 | · | · | |
| Quick Ratio | 1.1 | 1.4 | 7.1 | · | · |
Eficiencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Asset Turnover | 0.3 | 0.1 | 0.1 | · | · | |
| Receivables Turnover | 3.5 | 2.0 | 2.9 | · | · |
Tasas de Crecimiento 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue YoY | 38.9% | 0.38% | -81.6% | 1446.0% | -31.5% | |
| Revenue CAGR 3Y | -36.4% | 41.9% | 25.0% | · | · | |
| Revenue CAGR 5Y | 22.2% | · | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue TTM | $106M | $76M | $76M | $412M | · | |
| Net Income TTM | $-81M | $-123M | $-119M | $124M | · | |
| Market Cap | $1.97B | $1.01B | $729M | · | · | |
| P/E | -24.4 | -9.0 | -6.0 | 4.1 | · | |
| P/S | 18.5 | 13.2 | 9.6 | · | · | |
| P/B | 7.3 | 3.0 | 1.6 | · | · | |
| P / Tangible Book | 7.7 | 3.1 | 1.6 | 1.0 | · | |
| P / Cash Flow | -59.5 | -9.2 | -6.2 | · | · | |
| P / FCF | -56.9 | -9.0 | -6.0 | · | · | |
| Earnings Yield | -4.1% | -11.1% | -16.6% | 24.2% | · |
Estado de resultados 14
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $5M | $2M | $3M | $28M | $49M | $27M | $31M | $16M | $19M | $10M | $17M | $17M | $7M | $36M | $402M | $3M | |
| R&D Expense | · | · | · | · | · | · | · | · | · | $32M | · | $33M | $39M | $46M | · | $37M | |
| SG&A Expense | $19M | $15M | $15M | $14M | $15M | $17M | $16M | $14M | $16M | $16M | $15M | $17M | $22M | $17M | $30M | $16M | |
| Operating Expenses | $47M | $50M | $47M | $50M | $49M | $53M | $53M | $50M | $62M | $48M | $40M | $50M | $61M | $63M | $83M | $53M | |
| Operating Income | $-42M | $-47M | $-44M | $-22M | $-674.0K | $-26M | $-22M | $-34M | $-43M | $-38M | $-23M | $-33M | $-54M | $-27M | $319M | $-50M | |
| Other Non-op | $196.0K | $120.0K | $-18.0K | $26.0K | $-621.0K | $49.0K | $-253.0K | $-37.0K | $53.0K | $19.0K | $-278.0K | $370.0K | $230.0K | $-31.0K | $-27.0K | $-98.0K | |
| Pretax Income | $-45M | $-46M | $-41M | $-18M | $2M | $-22M | $-18M | $-30M | $-38M | $-32M | $-19M | $-28M | $-49M | $-23M | $320M | $-48M | |
| Income Tax | $-273.0K | $-2M | $-270.0K | $1M | $-186.0K | $496.0K | $6M | $226.0K | $68.0K | $75.0K | $-5M | $1M | $2M | $1M | $11M | $-29.0K | |
| Net Income | $-45M | $-44M | $-41M | $-20M | $2M | $-23M | $-24M | $-30M | $-38M | $-32M | $-14M | $-29M | $-51M | $-24M | $309M | $-48M | |
| EPS (Basic) | $-0.62 | $-0.59 | $-0.55 | $-0.26 | $0.03 | $-0.30 | $-0.32 | $-0.39 | $-0.49 | $-0.42 | $-0.19 | $-0.41 | $-0.76 | $-0.36 | $4.78 | $-0.72 | |
| EPS (Diluted) | $-0.62 | $-0.59 | $-0.55 | $-0.26 | $0.03 | $-0.30 | $-0.32 | $-0.39 | $-0.49 | $-0.42 | $-0.18 | $-0.41 | $-0.76 | $-0.37 | $4.78 | $-0.72 | |
| Shares (Basic) | 72,993,313 | 74,668,790 | -150,871,069 | 75,767,778 | 75,337,168 | 75,171,020 | -152,889,276 | 76,128,531 | 76,392,593 | 76,214,833 | -135,733,099 | 70,575,773 | 67,281,028 | 66,739,308 | -129,002,888 | 66,477,016 | |
| Shares (Diluted) | 72,993,313 | 74,694,762 | -152,966,654 | 75,775,214 | 77,378,449 | 75,226,387 | -152,922,738 | 76,157,101 | 76,396,217 | 76,248,158 | -135,739,304 | 70,575,773 | 67,284,511 | 66,742,030 | -128,961,927 | 66,478,157 | |
| EBITDA | $-42M | $-47M | · | $-22M | $-674.0K | $-26M | · | $-34M | $-43M | $-38M | · | $-33M | $-54M | $-27M | · | $-50M |
Balance general 23
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $179M | $244M | $41M | $65M | $98M | $76M | $66M | $122M | $71M | $115M | · | $94M | $142M | $182M | · | $96M | |
| Short-term Investments | · | · | · | · | · | · | · | · | · | · | · | $201M | $198M | $159M | · | $70M | |
| Receivables | $6M | $5M | $5M | $29M | $3M | $25M | $56M | $24M | $32M | $31M | · | $67M | $49M | $67M | · | $7M | |
| Prepaid Expense | $22M | $16M | $15M | $10M | $12M | $17M | $19M | $23M | $21M | $18M | · | $12M | $31M | $19M | · | $18M | |
| Current Assets | $298M | $386M | $249M | $292M | $296M | $306M | $300M | $344M | $383M | $394M | · | $375M | $420M | $426M | · | $191M | |
| PP&E (Net) | $14M | $15M | $16M | $16M | $16M | $17M | $18M | $18M | $18M | $19M | · | $21M | $22M | $24M | · | $26M | |
| PP&E (Gross) | · | · | $36M | · | · | · | $35M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $21M | · | · | · | $18M | · | · | · | · | · | · | · | · | · | |
| Goodwill | $12M | $12M | $12M | $12M | $12M | $12M | $12M | $12M | $12M | $12M | · | $12M | $12M | $12M | · | $12M | |
| Intangibles | $998.0K | $1M | $1M | $1M | $2M | $3M | $5M | $6M | $7M | $7M | · | $8M | $7M | $8M | · | $9M | |
| Total Assets | $397M | $478M | $347M | $397M | $408M | $426M | $463M | $487M | $516M | $554M | · | $556M | $602M | $601M | · | $300M | |
| Accounts Payable | $27M | $30M | $36M | $34M | $31M | $38M | $60M | $52M | $44M | $47M | · | $68M | $70M | $59M | · | $52M | |
| Current Liabilities | $47M | $36M | $42M | $42M | $39M | $65M | $88M | $84M | $55M | $57M | · | $73M | $94M | $67M | · | $58M | |
| Capital Leases | $13M | $14M | $15M | $16M | $15M | $15M | $16M | $17M | $17M | $21M | · | $22M | $23M | $24M | · | $25M | |
| Deferred Tax | $4M | $4M | $6M | $5M | $5M | $5M | $5M | $3M | $3M | $3M | · | $2M | $2M | $2M | · | $2M | |
| Other Non-current Liabilities | $278.0K | $278.0K | $278.0K | $278.0K | $828.0K | $856.0K | $923.0K | $929.0K | $1M | $2M | · | $2M | $4M | $4M | · | $3M | |
| Total Liabilities | $317M | $315M | $78M | $77M | $74M | $101M | $124M | $120M | $109M | $116M | · | $132M | $153M | $127M | · | $121M | |
| Common Stock | $1.13B | $1.13B | $1.11B | $1.09B | $1.07B | $1.02B | $1.02B | $1.01B | $1.01B | $1.00B | · | $932M | $929M | $900M | · | $885M | |
| Retained Earnings | $-1.17B | $-1.07B | $-953M | $-886M | $-851M | $-853M | $-830M | $-798M | $-747M | $-709M | · | $-663M | $-634M | $-583M | · | $-868M | |
| AOCI | $-7M | $-7M | $-6M | $-6M | $-6M | $-6M | $-7M | $-6M | $-8M | $-8M | · | $-8M | $-8M | $-6M | · | $-7M | |
| Stockholders' Equity | $80M | $164M | $269M | $320M | $335M | $325M | $339M | $367M | $406M | $438M | $465M | $424M | $449M | $474M | $493M | $180M | |
| Liabilities + Equity | $397M | $478M | $347M | $397M | $408M | $426M | $463M | $487M | $516M | $554M | · | $556M | $602M | $601M | · | $300M | |
| Shares Outstanding | 71,412,072 | 73,102,689 | 74,638,413 | 75,139,281 | 74,846,147 | 69,584,811 | 68,964,319 | 69,584,882 | 70,831,545 | 70,677,106 | · | 67,922,559 | 67,687,384 | 64,083,770 | · | 61,694,387 |
Flujo de Efectivo 12
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $11M | $7M | $9M | $7M | $6M | $6M | $5M | $5M | $5M | $4M | $3M | $2M | $367.0K | $2M | $4M | $5M | |
| Amort. of Intangibles | $176.0K | $176.0K | $185.0K | $648.0K | $2M | $2M | $2M | $980.0K | $812.0K | $702.0K | $673.0K | $672.0K | $678.0K | $679.0K | $529.0K | $166.0K | |
| Operating Cash Flow | $-32M | $-46M | $-10M | $-31M | $12M | $-3M | $-42M | $-6M | $-25M | $-38M | $14M | $-43M | $-6M | $-83M | $327M | $-73M | |
| CapEx | $0 | $216.0K | $581.0K | $410.0K | $514.0K | $16.0K | $314.0K | $899.0K | $593.0K | $185.0K | $356.0K | $930.0K | $802.0K | $386.0K | $348.0K | $981.0K | |
| Investing Cash Flow | $17M | $70M | $5M | $368.0K | $9M | $12M | $-6M | $72M | $-20M | $-7M | $-1M | $-7M | $-61M | $-138M | $-22M | $-30M | |
| Stock Issued | · | · | · | · | · | · | $0 | $0 | · | · | $0 | $0 | $26M | $0 | $0 | $0 | |
| Stock Repurchased | $52M | $76M | $25M | $16M | $0 | $0 | $9M | · | · | · | $0 | · | · | · | · | · | |
| Net Stock Activity | · | $-76M | · | · | · | · | · | · | · | · | · | · | · | $0 | · | · | |
| Financing Cash Flow | $-50M | $179M | $-19M | $-2M | $1M | $1M | $-9M | $-15M | $1M | $2M | $51M | $2M | $28M | $2M | $-377.0K | $628.0K | |
| Net Change in Cash | $-65M | $203M | $-24M | $-33M | $22M | $10M | $-56M | $51M | $-44M | $-43M | $63M | $-48M | $-39M | $-219M | $305M | $-103M | |
| Taxes Paid | $863.0K | $245.0K | $107.0K | $660.0K | $196.0K | $387.0K | $3M | $106.0K | $106.0K | $0 | · | · | · | · | · | · | |
| Free Cash Flow | · | $-46M | · | · | · | $-3M | · | · | · | $-38M | · | · | · | $-84M | · | · |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -919.0% | -1956.7% | · | -80.1% | -1.4% | -94.5% | · | -213.8% | -222.9% | -376.9% | · | -201.4% | -772.8% | -76.7% | · | -1914.0% | |
| Net Margin | -980.8% | -1834.0% | · | -71.0% | 4.8% | -83.5% | · | -186.6% | -195.8% | -315.6% | · | -173.8% | -730.5% | -68.5% | · | -1818.6% | |
| Pretax Margin | -986.8% | -1925.0% | · | -66.1% | 4.4% | -81.7% | · | -185.2% | -195.5% | -314.8% | · | -167.1% | -706.9% | -64.5% | · | -1819.7% | |
| EBITDA Margin | -919.0% | -1956.7% | · | -80.1% | -1.4% | -94.5% | · | -213.8% | -222.9% | -376.9% | · | -201.4% | -772.8% | -76.7% | · | -1914.0% | |
| ROA | -11.2% | -9.8% | · | -4.4% | 0.50% | -4.6% | · | -5.7% | -6.7% | -5.5% | · | -6.7% | -17.0% | -8.1% | · | -31.9% | |
| ROE | -21.7% | -18.1% | · | -5.7% | 0.63% | -5.9% | · | -7.5% | -8.8% | -6.9% | · | -9.5% | -22.8% | -10.3% | · | -53.2% | |
| ROIC | -52.2% | -27.4% | · | -7.4% | -0.22% | -8.1% | · | -9.4% | -10.6% | -8.6% | · | -8.2% | -12.5% | -6.1% | · | -28.0% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 6.3 | 10.8 | · | 6.9 | 7.7 | 4.7 | · | 4.1 | 7.0 | 6.9 | · | 5.1 | 4.5 | 6.3 | · | 3.3 | |
| Quick Ratio | 3.9 | 7.0 | · | 2.2 | 2.6 | 1.5 | · | 1.7 | 1.9 | 2.6 | · | 5.0 | 4.2 | 6.1 | · | 3.0 |
Eficiencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.1 | 0.1 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.1 | · | 0.0 | |
| Receivables Turnover | 1.1 | 0.2 | · | 1.0 | 2.8 | 1.0 | · | 0.4 | 0.5 | 0.2 | · | 0.4 | 0.3 | 1.1 | · | 0.8 |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $83M | $106M | · | $119M | $111M | $72M | · | $62M | $53M | $69M | · | $62M | $51M | $46M | · | $14M | |
| Net Income TTM | $-106M | $-84M | · | $-70M | $-88M | $-122M | · | $-128M | $-149M | $-136M | · | $-152M | $-188M | $-209M | · | $-246M | |
| Market Cap | $1.87B | $1.83B | · | $1.28B | $939M | $829M | · | $873M | $603M | $744M | · | $431M | $585M | $579M | · | $379M | |
| P/E | -18.2 | -22.4 | · | -18.6 | -10.9 | -7.4 | · | -7.3 | -4.1 | -5.4 | · | -2.8 | -3.1 | -2.8 | · | -1.5 | |
| P/S | 22.4 | 17.3 | · | 10.7 | 8.5 | 11.4 | · | 14.1 | 11.4 | 10.8 | · | 7.0 | 11.5 | 12.7 | · | 26.4 | |
| P/B | 23.2 | 11.2 | · | 4.0 | 2.8 | 2.6 | · | 2.4 | 1.5 | 1.7 | · | 1.0 | 1.3 | 1.2 | · | 2.1 | |
| P / Tangible Book | 27.7 | 12.2 | · | 4.2 | 2.9 | 2.7 | · | 2.5 | 1.6 | 1.8 | · | 1.1 | 1.4 | 1.3 | · | 2.4 | |
| P / Cash Flow | · | -40.0 | · | · | · | -243.3 | · | · | · | -19.7 | · | · | · | -7.0 | · | · | |
| P / FCF | · | -39.9 | · | · | · | -242.1 | · | · | · | -19.6 | · | · | · | -6.9 | · | · | |
| Earnings Yield | -5.5% | -4.5% | · | -5.4% | -9.2% | -13.4% | · | -13.6% | -24.4% | -18.6% | · | -35.6% | -32.6% | -35.9% | · | -67.2% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $106M | $76M | $76M | $412M | $27M |
| Margen Operativo % | -87.3% | -179.7% | -181.6% | — | — |
| Beneficio neto | $-81M | $-123M | $-119M | $124M | $-212M |
| EPS Diluido | $-1.08 | $-1.62 | $-1.72 | $1.90 | $-4.61 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 5.9 | 3.4 | 7.4 | — | — |
| Ratio Rápido | 1.1 | 1.4 | 7.1 | — | — |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-35M | $-112M | $-121M | — | — |
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Propietarios institucionales (13F) 218 declarantes · $1.5B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 30 (-4 vs trimestre anterior) | 29 (-2 vs trimestre anterior) | 56 (-17 vs trimestre anterior) | 68 (+9 vs trimestre anterior) | +2.6M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| EcoR1 Capital, LLC | $600 445 942 | 22 970 388 | 39,27% | Acciones |
| Rubric Capital Management LP | $182 980 000 | 7 000 000 | 11,97% | Acciones |
| PERCEPTIVE ADVISORS LLC | $109 342 391 | 4 182 953 | 7,15% | Acciones |
| BVF INC/IL | $95 388 572 | 3 649 142 | 6,24% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $40 752 208 | 1 558 998 | 2,67% | Acciones |
| Assenagon Asset Management S.A. | $32 727 986 | 1 252 027 | 2,14% | Acciones |
| Nextech Invest Ltd. | $29 118 548 | 1 113 946 | 1,90% | Acciones |
| STATE STREET CORP | $28 445 966 | 1 088 216 | 1,86% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $24 486 776 | 936 755 | 1,60% | Acciones |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $23 259 000 | 889 802 | 1,52% | Acciones |
| CITADEL ADVISORS LLC | $21 330 894 | 816 025 | 1,40% | Acciones |
| FMR LLC | $18 355 822 | 702 212 | 1,20% | Acciones |
| Prosight Management, LP | $17 629 705 | 674 434 | 1,15% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $16 322 460 | 624 447 | 1,07% | Acciones |
| Nextech Invest Ltd. | $16 308 169 | 1 113 946 | 1,07% | Acciones |
| Qube Research & Technologies Ltd | $15 516 443 | 593 590 | 1,01% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $13 332 236 | 510 032 | 0,87% | Acciones |
| Redmile Group, LLC | $12 851 836 | 491 654 | 0,84% | Acciones |
| Capricorn Fund Managers Ltd | $12 717 868 | 486 529 | 0,83% | Acciones |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $10 939 512 | 418 497 | 0,72% | Acciones |
| Hillsdale Investment Management Inc. | $10 009 581 | 382 922 | 0,65% | Acciones |
| GOLDMAN SACHS GROUP INC | $9 345 338 | 357 511 | 0,61% | Acciones |
| FIRST TRUST ADVISORS LP | $8 897 088 | 340 363 | 0,58% | Acciones |
| Granahan Investment Management, LLC | $8 787 144 | 336 157 | 0,57% | Acciones |
| Pictet Asset Management Holding SA | $7 446 189 | 308 187 | 0,49% | Acciones |
| PICTON MAHONEY ASSET MANAGEMENT | $7 092 908 | 271 343 | 0,46% | Acciones |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $5 849 243 | 223 766 | 0,38% | Acciones |
| SummitTX Capital, L.P. | $5 510 364 | 210 802 | 0,36% | Acciones |
| Man Group plc | $5 509 763 | 210 779 | 0,36% | Acciones |
| BANK OF AMERICA CORP /DE/ | $5 182 437 | 198 257 | 0,34% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $4 066 835 | 155 579 | 0,27% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3 984 154 | 152 416 | 0,26% | Acciones |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3 960 132 | 151 497 | 0,26% | Acciones |
| KENNEDY CAPITAL MANAGEMENT LLC | $3 800 390 | 145 386 | 0,25% | Acciones |
| D. E. Shaw & Co., Inc. | $3 785 255 | 144 807 | 0,25% | Acciones |
| DIADEMA PARTNERS LP | $3 715 330 | 142 132 | 0,24% | Acciones |
| BlackRock, Inc. | $3 614 744 | 138 284 | 0,24% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3 408 656 | 130 400 | 0,22% | Opción de compra |
| CITIGROUP INC | $3 364 872 | 128 725 | 0,22% | Acciones |
| XTX Topco Ltd | $3 290 425 | 125 877 | 0,22% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $3 100 282 | 118 603 | 0,20% | Acciones |
| PLATINUM INVESTMENT MANAGEMENT LTD | $2 749 510 | 105 184 | 0,18% | Acciones |
| AXA Investment Managers S.A. | $2 705 745 | 158 416 | 0,18% | Acciones |
| Manatuck Hill Partners, LLC | $2 614 000 | 100 000 | 0,17% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2 451 932 | 93 800 | 0,16% | Opción de venta |
| KORNITZER CAPITAL MANAGEMENT INC /KS | $2 321 232 | 88 800 | 0,15% | Acciones |
| MACKENZIE FINANCIAL CORP | $2 293 654 | 87 745 | 0,15% | Acciones |
| VANGUARD GROUP INC | $2 251 979 | 85 529 | 0,15% | Acciones |
| Y-Intercept (Hong Kong) Ltd | $2 181 514 | 83 455 | 0,14% | Acciones |
| LMR Partners LLP | $2 156 550 | 82 500 | 0,14% | Acciones |
| PRINCIPAL FINANCIAL GROUP INC | $2 127 587 | 81 392 | 0,14% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $2 094 337 | 80 120 | 0,14% | Acciones |
| TEMA ETFS LLC | $2 000 422 | 75 975 | 0,13% | Acciones |
| RHUMBLINE ADVISERS | $1 962 211 | 75 066 | 0,13% | Acciones |
| Swiss National Bank | $1 939 588 | 74 200 | 0,13% | Acciones |
| MARTINGALE ASSET MANAGEMENT L P | $1 915 592 | 73 282 | 0,13% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $1 878 786 | 71 874 | 0,12% | Acciones |
| Dana Investment Advisors, Inc. | $1 873 192 | 71 660 | 0,12% | Acciones |
| CREDIT AGRICOLE S A | $1 855 940 | 71 000 | 0,12% | Acciones |
| Fisher Asset Management, LLC | $1 850 057 | 70 775 | 0,12% | Acciones |
| SEGALL BRYANT & HAMILL, LLC | $1 747 093 | 66 836 | 0,11% | Acciones |
| Verdad Advisers, LP | $1 743 224 | 66 688 | 0,11% | Acciones |
| Susquehanna Portfolio Strategies, LLC | $1 705 583 | 65 248 | 0,11% | Acciones |
| Campbell & CO Investment Adviser LLC | $1 591 246 | 60 874 | 0,10% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $1 399 636 | 55 896 | 0,09% | Acciones |
| CITADEL ADVISORS LLC | $1 364 508 | 52 200 | 0,09% | Opción de compra |
| Virtus Investment Advisers, LLC | $1 328 566 | 50 825 | 0,09% | Acciones |
| ENVESTNET ASSET MANAGEMENT INC | $1 272 365 | 48 675 | 0,08% | Acciones |
| Quantinno Capital Management LP | $1 245 362 | 47 642 | 0,08% | Acciones |
| WELLS FARGO & COMPANY/MN | $1 122 164 | 42 929 | 0,07% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $1 111 577 | 42 524 | 0,07% | Acciones |
| Bank of New York Mellon Corp | $1 076 785 | 41 193 | 0,07% | Acciones |
| MARSHALL WACE, LLP | $1 070 380 | 40 948 | 0,07% | Acciones |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | $1 033 419 | 39 534 | 0,07% | Acciones |
| Aquilo Capital Management, LLC | $1 006 181 | 84 482 | 0,07% | Acciones |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $965 141 | 36 922 | 0,06% | Acciones |
| TUDOR INVESTMENT CORP ET AL | $953 352 | 36 471 | 0,06% | Acciones |
| HighTower Advisors, LLC | $943 654 | 36 100 | 0,06% | Acciones |
| Persistent Asset Partners Ltd | $939 341 | 35 935 | 0,06% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $936 221 | 37 389 | 0,06% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $904 653 | 34 608 | 0,06% | Acciones |
| HighVista Strategies LLC | $889 100 | 34 013 | 0,06% | Acciones |
| COMMONWEALTH EQUITY SERVICES, LLC | $837 838 | 32 052 | 0,05% | Acciones |
| TWO SIGMA ADVISERS, LP | $827 157 | 31 415 | 0,05% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $807 360 | 30 886 | 0,05% | Acciones |
| SBI Okasan Asset Management Co.Ltd. | $771 200 | 32 000 | 0,05% | Acciones |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $735 529 | 27 935 | 0,05% | Acciones |
| MetLife Investment Management, LLC | $728 888 | 27 884 | 0,05% | Acciones |
| JOURNEY STRATEGIC WEALTH LLC | $722 304 | 28 846 | 0,05% | Acciones |
| STRS OHIO | $692 710 | 26 500 | 0,05% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $686 933 | 26 279 | 0,04% | Acciones |
| Brevan Howard Capital Management LP | $678 490 | 25 956 | 0,04% | Acciones |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $657 735 | 25 162 | 0,04% | Acciones |
| RITHOLTZ WEALTH MANAGEMENT | $633 712 | 24 243 | 0,04% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $607 206 | 23 229 | 0,04% | Acciones |
| Duncan Williams Asset Management, LLC | $577 563 | 22 095 | 0,04% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $564 049 | 21 578 | 0,04% | Acciones |
| BARCLAYS PLC | $524 577 | 20 068 | 0,03% | Acciones |
| SIMPLEX TRADING, LLC | $507 926 | 19 431 | 0,03% | Acciones |
| Invesco Ltd. | $491 720 | 18 811 | 0,03% | Acciones |
Informantes de la empresa 28 insiders · 12 directivos · 17 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Kenneth Galbraith | Chair & CEO | 12 de enero de 2026 A | 226 842 | 0 | 4 | $-3 337 929 |
| Kristin Stafford | EVP, Chief Financial Officer | 6 de abril de 2026 A | — | 0 | 0 | $0 |
| Christopher Astle | SVP & Chief Financial Officer | 5 de enero de 2024 A | 6 503 | 0 | 0 | $0 |
| Neil A Klompas | President & COO | 10 de marzo de 2023 M | 17 032 | 0 | 0 | $0 |
| Mark Hollywood | EVP & Chief Operating Officer | 6 de julio de 2026 A | 133 852 | 0 | 1 | $-138 740 |
| Paul R Schneider | EVP, General Counsel | 13 de mayo de 2026 A | — | 0 | 0 | $0 |
| Adam Schayowitz | EVP, Head of Research & Development | 9 de abril de 2026 A | — | 0 | 0 | $0 |
| Scott Platshon | EVP, Chief Business Officer | 9 de abril de 2026 A | — | 0 | 0 | $0 |
| Paul Andrew Moore | Chief Scientific Officer | 12 de enero de 2026 A | 48 497 | 0 | 3 | $-721 486 |
| Jeffrey T L Smith | EVP & Chief Medical Officer | 12 de enero de 2026 M | 26 708 | 0 | 2 | $-475 562 |
| Leone D Patterson | EVP, Chief Bus & Fin Officer | 6 de enero de 2026 A | 459 | 0 | 0 | $0 |
| Neil Josephson | Chief Medical Officer | 10 de noviembre de 2022 M | 14 449 | 0 | 0 | $0 |
| Gregory A. Ciongoli | Consejero | 12 de enero de 2026 A | 488 500 | 0 | 0 | $0 |
| Alessandra Cesano | Consejero | 12 de enero de 2026 A | — | 0 | 0 | $0 |
| Carlos Campoy | Consejero | 12 de enero de 2026 A | — | 0 | 0 | $0 |
| Robert E Landry | Consejero | 12 de enero de 2026 A | — | 0 | 0 | $0 |
| Kelvin Neu | Consejero | 12 de enero de 2026 A | — | 0 | 0 | $0 |
| Susan Mahony | Consejero | 12 de enero de 2026 A | — | 0 | 0 | $0 |
| Brian N Cherry | Consejero | 12 de enero de 2026 A | — | 0 | 0 | $0 |
| EcoR1 Capital, LLC | Consejero | 17 de enero de 2025 P | 15 720 161 | 0 | 0 | $0 |
| Nancy Davidson | Consejero | 10 de diciembre de 2024 A | — | 0 | 0 | $0 |
| Neil Gallagher | Consejero | 10 de diciembre de 2024 A | — | 0 | 0 | $0 |
| Derek John Michael Miller | Consejero | 10 de diciembre de 2024 A | — | 0 | 0 | $0 |
| Troy Cox | Consejero | 10 de diciembre de 2024 A | — | 0 | 0 | $0 |
| Kenneth J. Hillan | Consejero | 7 de diciembre de 2023 A | — | 0 | 0 | $0 |
| Hollings Renton | Consejero | 7 de diciembre de 2023 A | — | 0 | 0 | $0 |
| Natalie Sacks | Consejero | 21 de diciembre de 2022 A | — | 0 | 0 | $0 |
| Lota S. Zoth | Consejero | 21 de diciembre de 2022 A | — | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 2 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC, Oleg Nodelman, EcoR1 Capital Fund Qualified, L.P. ×8 presentaciones | 19 de noviembre de 2025 | 30,70% | Enmienda | Campaña de la junta directiva | SEC |
| All Blue Falcons FZE, Daniel Edward Llewellen Cookson ×2 presentaciones | 28 de diciembre de 2022 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 41 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| CANC · Tema ETF Trust | 1,51% | 105 615 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,80% | 10 832 NS | 30 de abril de 2026 | N-PORT |
| FYC · First Trust Exchange-Traded AlphaDE… | 0,49% | 186 247 NS | 30 de abril de 2026 | N-PORT |
| FYX · First Trust Exchange-Traded AlphaDE… | 0,25% | 110 902 NS | 30 de abril de 2026 | N-PORT |
| FSCC · Federated Hermes ETF Trust | 0,15% | 16 669 NS | 31 de mayo de 2026 | N-PORT |
| SMMV · iShares Trust | 0,13% | 16 160 SH | 8 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,13% | 517 328 SH | 8 de agosto de 2026 | Diario |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,12% | 14 789 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,12% | 3 975 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,10% | 74 514 SH | 8 de agosto de 2026 | Diario |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,10% | 17 393 NS | 30 de abril de 2026 | N-PORT |
| BIB · ProShares Trust | 0,09% | 2 766 NS | 31 de mayo de 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,07% | 50 443 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,07% | 423 822 SH | 8 de agosto de 2026 | Diario |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,06% | 67 771 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,04% | 21 639 NS | 30 de abril de 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,04% | 270 692 SH | 8 de agosto de 2026 | Diario |
| DFAS · Dimensional ETF Trust | 0,04% | 189 866 NS | 30 de abril de 2026 | N-PORT |
| IWM · iShares Trust | 0,03% | 1 183 337 SH | 8 de agosto de 2026 | Diario |
| ITWO · ProShares Trust | 0,03% | 2 345 NS | 31 de mayo de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,03% | 10 887 NS | 31 de mayo de 2026 | N-PORT |
| ISCV · iShares Trust | 0,02% | 5 753 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,02% | 1 834 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,02% | 16 794 NS | 30 de abril de 2026 | N-PORT |
| ISCB · iShares Trust | 0,02% | 1 999 SH | 8 de agosto de 2026 | Diario |
| ISCG · iShares Trust | 0,01% | 5 891 SH | 8 de agosto de 2026 | Diario |
| URTY · ProShares Trust | 0,01% | 1 855 NS | 31 de mayo de 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 3 008 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,01% | 110 298 SH | 8 de agosto de 2026 | Diario |
| TILT · FlexShares Trust | 0,01% | 5 236 NS | 30 de abril de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 1 925 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 26 839 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 47 NS | 31 de mayo de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 5 213 NS | 30 de abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 72 902 NS | 30 de abril de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 12 951 NS | 30 de abril de 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 14 256 SH | 8 de agosto de 2026 | Diario |
| DFUS · Dimensional ETF Trust | 0,00% | 8 364 NS | 30 de abril de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 130 NS | 30 de abril de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1 508 613 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 4 085 SH | 8 de agosto de 2026 | Diario |