ABUS Arbutus Biopharma Corporation - Common Stock

NASDAQ · Biotechnology · Ver en SEC EDGAR ↗
$5,01
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 12, 2026

Acerca de Arbutus Biopharma Corporation - Common Stock Descripción general de la empresa de Wikipedia

Arbutus Biopharma Corporation is a publicly traded Canadian biopharmaceutical company with an expertise in liposomal drug delivery and RNA interference, and is developing drugs for hepatitis B infection.

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Arbutus Biopharma Corporation is a publicly traded Canadian (NASDAQ: ABUS) biopharmaceutical company with an expertise in liposomal drug delivery and RNA interference, and is developing drugs for hepatitis B infection.

It is headquartered in Warminster, Pennsylvania. The company was formerly known as Tekmira, which was spun out of Inex Pharmaceuticals in 2007.

History

Tekmira, as the company was formerly called, was formed as a wholly owned subsidiary of Inex Pharmaceuticals in 2005 after that company began collapsing after its regulatory and partnering strategy failed in 2004. Tekmira was fully spun out in 2007 and Tekmira absorbed the assets of Inex, which had been founded in 1992.

Inex had been developing liposomal formulations of off-patent cancer drugs, and licensed them to Talon Pharmaceuticals in 2005; Talon was acquired by Spectrum Pharmaceuticals in 2013, and three former Inex/Tekmira products reached the market and began generating royalties for Tekmira: Marqibo (liposomal vincristine), Alocrest (liposomal vinorelbine) and Brakiva (liposomal topotecan).

Inex had also acquired licenses to intellectual property, as well as staff and manufacturing facilities, concerning RNAi technology from Lynx Therapeutics in 1998; this set of technologies became the focus for Tekmira and it initially sought to develop liposomally encapsulated RNAi drugs for a broad range of indications.

Tekmira also worked on providing liposomal delivery technology to other companies. In 2007 it signed a license agreement with Alnylam Pharmaceuticals so that Alnylam could use it to deliver its own RNAi drugs; that deal was expanded into a manufacturing agreement in 2009.

Most of those products not focused on viral diseases faltered, and Tekmira had only $6.3 million in cash when it filed suit against Alnylam in 2011 for breaching its contract and stealing trade secrets. The suit was settled in 2012, with Alnylam agreeing to pay Tekmira $65 million in termination fees, and the companies negotiated a new license agreement with lower milestones and royalties, which covers Alnylam's product patisiran.

Tekmira caught the world's attention and its stock rose dramatically during the 2013 West African Ebola virus epidemic due to its drug candidate for Ebola fever, TKM-Ebola. Tekmira was developing it under a $140 million US Department of Defense contract. While its stock was trading high in January 2015, it acquired OnCore BioPharma, a company focused on hepatitis B.

On December 19, 2014, Tekmira announced the appointment of former Bill & Melinda Gates Foundation CFO Richard Henriques to the company's board of directors. The company simultaneously announced the forthcoming departure of Ian MacLachlan as Executive Vice President and Chief Technical Officer.

Development of TKM-Ebola was terminated in mid June 2015 during a Phase II trial, for lack of efficacy.

The next month, Tekmira changed its name to Arbutus Biopharma and said that it would focus on drugs to treat hepatitis B.

In March 2017 Arbutus signed another license for its liposome delivery technology, this time with Alexion Pharmaceuticals, for delivery of an mRNA drug candidate. This license was terminated in July 2017, when Alexion discontinued preclinical programs outside its core complement franchise.

In 2019, Arbutus began a phase 1 clinical study using AB-506 to treat chronic hepatitis B. The company released preliminary data in July and stopped the trial in October after two patients developed acute hepatitis. Now AB-729 is paving the way for Arbutus, as they recently received the FDA go ahead to pursue phase 2 trials, after having their data voted best in ILC, 2021; after abandoning development of previous investigational agents. AB-836, Arbutus's next generation capsid inhibitor, has shown potential against mutants in its phase 1 trials.

In July 2019, Arbutus Biopharma announced the sale of part of its royalty interest on future global net sales of ONPATTRO, an RNA interference therapeutic currently sold by Alnylam Pharmaceuticals, to OMERS for $20 million.

COVID-19

On March 10, 2023, U.S. District Judge Mitchell Goldberg rejected a bid by Moderna to dismiss some of the patent infringement claims brought against the company by Arbutus and its partner, Genevant Sciences.

Moderna settled their lawsuit and will pay Arbutus $950 million upfront and an additional $1.3 billion contingent upon a favorable resolution of Moderna’s Section 1498 appeal.

Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗

Wikidata ↗

ABUS Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas

Precio
$5.01
Capitalización Bursátil
$987M
P/E (TTM)
-30.1
BPA (TTM)
$-0.17
Ingresos (TTM)
$14M
Rendimiento div.
ROE
-42.0%
Deuda/Capital
Rango 52S
$3 – $5

ABUS Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista

Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA

Ingresos y Beneficio Neto $14M
10-point trend, +844.5%
2016-12-31 2025-12-31
BPA $-0.17
9-point trend, +97.7%
2016-12-31 2025-12-31
Flujo de caja libre $-40M
9-point trend, +35.9%
2016-12-31 2025-12-31
Márgenes -237.9%

Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?

Métrica
Tendencia a 5 años
ABUS
Mediana de Pares
P/E (TTM)
5-point trend, -503.7%
-30.1
6.7
P/S (TTM) (P/V (TTM))
5-point trend, +28.1%
70.1
39.8
P/B (P/C)
5-point trend, +263.3%
12.9
4.8
Price / FCF (Precio / FCF)
5-point trend, -183.1%
-24.9

Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC

Métrica
Tendencia a 5 años
ABUS
Mediana de Pares
Operating Margin (Margen Operativo)
5-point trend, +59.5%
-271.0%
Net Profit Margin (Margen de Beneficio Neto)
5-point trend, +65.7%
-237.9%
-220.1%
ROA
5-point trend, +33.7%
-29.6%
-35.0%
ROE
5-point trend, +17.5%
-42.0%
-43.2%

Salud financiera Deuda, liquidez, solvencia — solidez del balance general

Métrica
Tendencia a 5 años
ABUS
Mediana de Pares
Current Ratio (Ratio corriente)
5-point trend, +9.8%
15.7
9.7
Quick Ratio (Ratio Rápido)
5-point trend, +11.1%
15.5

Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años

Métrica
Tendencia a 5 años
ABUS
Mediana de Pares
Revenue YoY (Ingresos interanuales)
5-point trend, +28.2%
128.2%
Revenue CAGR 3Y (Ingresos CAGR 3A)
5-point trend, +28.2%
-28.8%
Revenue CAGR 5Y (Ingresos CAGR 5A)
5-point trend, +28.2%
15.3%

Métricas por acción BPA, valor contable por acción, flujo de caja por acción, dividendo por acción

Métrica
Tendencia a 5 años
ABUS
Mediana de Pares
EPS (Diluted) (BPA (Diluido))
5-point trend, +79.5%
$-0.17

Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar

Métrica
Tendencia a 5 años
ABUS
Mediana de Pares

ABUS Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista

COMPRA 8 analistas
  • Compra fuerte 3 37,5%
  • Compra 4 50,0%
  • Mantener 1 12,5%
  • Venta 0 0,0%
  • Venta fuerte 0 0,0%

Precio objetivo a 12 meses

1 analistas · 2026-08-17
Objetivo mediano $5.53 +10,3%
Objetivo medio $5.53 +10,3%

Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados

Sorpresa Media
0.01%
Período EPS Actual EPS est. Sorpresa
31 de marzo de 2026 $-0.05 $-0.03 -0.02%
31 de diciembre de 2025 $-0.02 $-0.04 0.02%
30 de septiembre de 2025 $-0.04 $-0.03 -0.01%
30 de junio de 2025 $0.01 $-0.05 0.06%
31 de marzo de 2025 $-0.13 $-0.11 -0.02%
31 de diciembre de 2024 $-0.07 $-0.08 0.01%

Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector

Ticker Capitalización Bursátil P/E Ingresos interanuales Margen Neto ROE Margen Bruto
ABUS $926M -28.3 128.2% -237.9% -42.0%
XENE $3.59B -10.3 -4612.1% -56.9%
AUPH $2.11B 7.7 20.4% 101.5% 62.7%
ZYME $1.97B -24.4 38.9% -76.6% -26.9%
ACOG $141M -5.5 -202.2% -43.8%

Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja

Estado de resultados 16
Datos anuales de Estado de resultados para ABUS
Métrica Tendencia 20252024202320222021202020192018201720162015
Revenue 11-point trend, -39.5% $14M $6M $18M $39M $11M $7M $6M $6M $11M $1M $23M
R&D Expense 11-point trend, -51.0% $25M $54M $74M $84M $66M $49M $58M $58M $63M $61M $52M
SG&A Expense 11-point trend, -39.9% $16M $22M $22M $18M $17M $15M $18M $16M $16M $39M $26M
Operating Expenses 11-point trend, -58.9% $52M $82M $96M $104M $85M $65M $150M $96M $122M $493M $127M
Operating Income 11-point trend, +63.3% $-38M $-76M $-78M $-65M $-74M $-58M $-144M $-90M $-111M $-492M $-104M
Interest Expense 9-point trend, +459000.00 · · $459.0K $2M $3M $4M $2M $226.0K $261.0K $0 $0
Interest Income 11-point trend, +503.6% $4M $7M $6M $2M $127.0K $741.0K $2M $3M $2M $1M $674.0K
Other Non-op 11-point trend, -81.4% $5M $6M $5M $444.0K $-3M $-6M $-22M $28M $2M $2M $25M
Pretax Income 6-point trend, +19.2% · · · · · $-64M $-166M $-61M $-109M $-489M $-79M
Income Tax 11-point trend, +100.0% $0 $0 $0 $4M $0 $0 $-13M $-4M $-24M $-105M $-16M
Net Income 11-point trend, +46.6% $-34M $-70M $-73M $-69M $-76M $-64M $-154M $-57M $-84M $-384M $-63M
EPS (Basic) 10-point trend, +87.7% $-0.17 $-0.38 $-0.44 $-0.46 $-0.83 $-1.00 · $-1.21 $-1.56 $-7.24 $-1.38
EPS (Diluted) 10-point trend, +87.7% $-0.17 $-0.38 $-0.44 $-0.46 $-0.83 $-1.00 · $-1.21 $-1.56 $-7.24 $-1.38
Shares (Basic) 10-point trend, +321.4% 191,599,600 185,608,874 165,960,379 150,939,337 106,242,452 75,835,378 · 55,304,083 54,723,272 53,074,401 45,462,324
Shares (Diluted) 10-point trend, +321.4% 191,599,600 185,608,874 165,960,379 150,939,337 106,242,452 75,835,378 · 55,304,083 54,723,272 53,074,401 45,462,324
EBITDA 9-point trend, +92.2% $-38M $-76M $-78M $-65M $-74M $-58M · $-90M $-111M $-492M ·
Balance general 25
Datos anuales de Balance general para ABUS
Métrica Tendencia 20252024202320222021202020192018201720162015
Cash & Equivalents 11-point trend, -89.2% $18M $36M $26M $31M $109M $52M $32M $37M $54M $23M $167M
Short-term Investments 11-point trend, +405.8% $73M $86M $100M $116M $46M $71M $59M $88M $72M $107M $15M
Receivables 11-point trend, +43.6% $1M $2M $2M $1M $899.0K $1M $1M $1M $402.0K $273.0K $1M
Prepaid Expense 11-point trend, +28.6% $2M $2M $4M $3M $4M $3M $2M $3M $2M $1M $1M
Current Assets 11-point trend, -48.6% $94M $127M $132M $151M $161M $128M $94M $129M $129M $133M $184M
PP&E (Net) 11-point trend, -99.0% $32.0K $3M $5M $5M $6M $7M $9M $10M $12M $7M $3M
PP&E (Gross) 11-point trend, -98.1% $245.0K $16M $17M $16M $15M $15M $14M $17M $25M $18M $13M
Accum. Depreciation 11-point trend, -97.8% $213.0K $13M $12M $11M $9M $8M $6M $7M $13M $11M $10M
Goodwill 5-point trend, -100.0% · · · · · · $0 $22M $24M $24M $163M
Intangibles 5-point trend, -100.0% · · · · · · $0 $44M $59M $99M $353M
Other Non-current Assets 8-point trend, +130000.00 $130.0K $34.0K $0 $103.0K $61.0K $44.0K $293.0K $0 · · ·
Total Assets 11-point trend, -86.7% $95M $132M $144M $195M $204M $137M $106M $228M $237M $276M $712M
Accounts Payable 11-point trend, -38.2% $5M $8M $10M $16M $11M $9M $7M $9M $11M $10M $9M
Current Liabilities 11-point trend, -43.2% $6M $16M $22M $33M $11M $10M $8M $11M $15M $11M $11M
Capital Leases 8-point trend, +199000.00 $199.0K $806.0K $1M $2M $2M $3M $3M $0 · · ·
Deferred Tax 5-point trend, -100.0% · · · · · · $0 $13M $17M $41M $146M
Total Liabilities 11-point trend, -89.0% $18M $34M $38M $59M $35M $35M $33M $28M $55M $73M $165M
Long-term Debt Flat — no change across 5 periods $0 $0 $0 $0 $0 · · · · · ·
Common Stock 11-point trend, +70.4% $1.42B $1.41B $1.35B $1.32B $1.29B $986M $899M $879M $876M $867M $834M
Paid-in Capital 11-point trend, +175.8% $83M $82M $81M $72M $65M $61M $55M $48M $43M $37M $30M
Retained Earnings 11-point trend, -416.9% $-1.38B $-1.35B $-1.28B $-1.20B $-1.13B $-1.05B $-970M $-805M $-738M $-653M $-267M
AOCI 11-point trend, +3.4% $-48M $-48M $-48M $-50M $-48M $-48M $-48M $-48M $-48M $-48M $-50M
Stockholders' Equity 11-point trend, -86.0% $77M $97M $106M $137M $169M $102M $73M $200M $182M $203M $548M
Liabilities + Equity 11-point trend, -86.7% $95M $132M $144M $195M $204M $137M $106M $228M $237M $276M $712M
Shares Outstanding 11-point trend, +252.8% 192,531,225 189,963,492 169,867,414 157,455,363 144,987,736 89,678,722 64,780,314 55,518,800 55,060,650 54,841,494 54,570,691
Flujo de Efectivo 14
Datos anuales de Flujo de Efectivo para ABUS
Métrica Tendencia 20252024202320222021202020192018201720162015
Stock-based Comp 9-point trend, -54.0% $7M $9M $9M $7M $6M $6M $7M $6M $15M · ·
Deferred Tax 6-point trend, +100.0% · · · · · $0 $-13M $-4M $-24M $-105M $-16M
Restructuring 8-point trend, +12939000.00 $13M $4M $0 · $0 $64.0K $156.0K $5M $0 · ·
Operating Cash Flow 11-point trend, +29.7% $-40M $-65M $-86M $-35M $-68M $-51M $-71M $-68M $-49M $-58M $-56M
CapEx 11-point trend, -100.0% $0 $182.0K $1M $512.0K $809.0K $229.0K $589.0K $1M $7M $4M $2M
Investing Cash Flow 11-point trend, +102.8% $16M $23M $51M $-75M $-13M $-15M $28M $-4M $28M $-99M $8M
Debt Issued 3-point trend, +0.00 · · · · · · · · $0 $12M $0
Net Debt Issued 2-point trend, -100.0% · · · · · · · · $0 $12M ·
Stock Issued 7-point trend, -5.3% · · · · $135M $86M $19M $0 $0 $0 $142M
Net Stock Activity 4-point trend, +134665000.00 · · · · $135M $86M · · $0 $0 ·
Financing Cash Flow 11-point trend, -96.0% $6M $52M $31M $32M $137M $87M $37M $56M $49M $13M $144M
Net Change in Cash 11-point trend, -119.4% $-18M $10M $-4M $-79M $57M $20M $-5M $-17M $31M $-143M $95M
Free Cash Flow 9-point trend, +35.9% $-40M $-65M $-87M $-36M $-68M $-52M · $-69M $-56M $-62M ·
Levered FCF 3-point trend, +0.8% · · · · · $-56M · $-69M $-56M · ·
Rentabilidad 7
Datos anuales de Rentabilidad para ABUS
Métrica Tendencia 20252024202320222021202020192018201720162015
Operating Margin 9-point trend, +99.2% -271.0% -1236.7% -430.5% -167.8% -669.1% -836.1% · -1510.2% -1036.7% -32973.8% ·
Net Margin 9-point trend, +99.1% -237.9% -1133.0% -401.6% -178.0% -693.9% -922.0% · -959.8% -788.9% -25765.5% ·
Pretax Margin 4-point trend, +97.2% · · · · · -922.0% · -1031.8% -1016.2% -32807.9% ·
EBITDA Margin 9-point trend, +99.2% -271.0% -1236.7% -430.5% -167.8% -669.1% -836.1% · -1510.2% -1036.7% -32973.8% ·
ROA 9-point trend, +61.9% -29.6% -50.6% -42.9% -34.7% -44.6% -52.5% · -24.5% -32.9% -77.8% ·
ROE 9-point trend, +59.0% -42.0% -68.5% -64.6% -49.2% -50.9% -64.0% · -27.5% -43.8% -102.4% ·
ROIC 4-point trend, +70.2% · · · · · -56.7% · -41.7% -47.2% -190.2% ·
Liquidez y Solvencia 3
Datos anuales de Liquidez y Solvencia para ABUS
Métrica Tendencia 20252024202320222021202020192018201720162015
Current Ratio 9-point trend, +25.6% 15.7 8.2 5.9 4.6 14.3 13.4 · 11.5 8.8 12.5 ·
Quick Ratio 9-point trend, +25.2% 15.5 8.0 5.7 4.5 13.9 13.1 · 11.2 8.7 12.4 ·
Interest Coverage 6-point trend, +60.0% · · -170.2 -37.9 -25.7 -14.4 · -397.3 -425.0 · ·
Eficiencia 2
Datos anuales de Eficiencia para ABUS
Métrica Tendencia 20252024202320222021202020192018201720162015
Asset Turnover 9-point trend, +4046.7% 0.1 0.0 0.1 0.2 0.1 0.1 · 0.0 0.0 0.0 ·
Receivables Turnover 9-point trend, +213.8% 7.3 2.9 11.6 34.7 9.9 5.5 · 6.5 31.7 2.3 ·
Por Acción 5
Datos anuales de Por Acción para ABUS
Métrica Tendencia 20252024202320222021202020192018201720162015
Book Value / Share 9-point trend, -89.3% $0.40 $0.51 $0.62 $0.87 $1.17 $1.14 · $3.61 $3.31 $3.70 ·
Revenue / Share 8-point trend, +161.6% $0.07 $0.03 $0.11 $0.26 $0.10 · · $0.11 $0.20 $0.03 ·
Cash Flow / Share 8-point trend, +81.0% $-0.21 $-0.35 $-0.52 $-0.23 $-0.64 · · $-1.23 $-0.89 $-1.09 ·
Cash / Share 9-point trend, -78.1% $0.09 $0.19 $0.15 $0.20 $0.75 $0.58 · $0.67 $0.99 $0.43 ·
EPS (TTM) 11-point trend, +87.7% $-0.17 $-0.38 $-0.44 $-0.46 $-0.83 $-1.00 $-1.32 $-1.21 $-1.56 $-7.24 $-1.38
Tasas de Crecimiento 3
Datos anuales de Tasas de Crecimiento para ABUS
Métrica Tendencia 20252024202320222021202020192018201720162015
Revenue YoY 5-point trend, +117.6% 128.2% -66.0% -53.5% 255.1% 58.9% · · · · · ·
Revenue CAGR 3Y 3-point trend, -175.9% -28.8% -17.5% 37.9% · · · · · · · ·
Revenue CAGR 5Y 15.3% · · · · · · · · · ·
Valoración (TTM) 10
Datos anuales de Valoración (TTM) para ABUS
Métrica Tendencia 20252024202320222021202020192018201720162015
Revenue TTM 11-point trend, -39.5% $14M $6M $18M $39M $11M $7M $6M $6M $11M $1M $23M
Net Income TTM 11-point trend, +46.6% $-34M $-70M $-73M $-69M $-76M $-64M $-154M $-57M $-84M $-384M $-63M
Market Cap 9-point trend, +589.2% $926M $621M $425M $367M $564M $318M · $213M $278M $134M ·
P/E 11-point trend, -777.4% -28.3 -8.6 -5.7 -5.1 -4.7 -3.5 -2.1 -3.2 -3.2 -0.3 -3.2
P/S 9-point trend, -27.0% 65.8 100.7 23.4 9.4 51.3 46.0 · 35.8 26.0 90.1 ·
P/B 9-point trend, +1727.1% 12.1 6.4 4.0 2.7 3.3 3.1 · 1.1 1.5 0.7 ·
P / Tangible Book 6-point trend, +287.3% 12.1 6.4 4.0 2.7 3.3 3.1 · · · · ·
P / Cash Flow 9-point trend, -906.5% -23.4 -9.6 -4.9 -10.4 -8.4 -6.2 · -3.1 -5.7 -2.3 ·
P / FCF 9-point trend, -976.0% -23.4 -9.6 -4.9 -10.2 -8.3 -6.2 · -3.1 -5.0 -2.2 ·
Earnings Yield 11-point trend, +88.6% -3.5% -11.6% -17.6% -19.7% -21.3% -28.2% -47.5% -31.6% -30.9% -295.5% -31.0%

Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años

Estado de resultados
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ingresos $14M$6M$18M$39M$11M
Margen Operativo % -271.0%-1236.7%-430.5%-167.8%-669.1%
Beneficio neto $-34M$-70M$-73M$-69M$-76M
EPS Diluido $-0.17$-0.38$-0.44$-0.46$-0.83
Balance general
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ratio corriente 15.78.25.94.614.3
Ratio Rápido 15.58.05.74.513.9
Flujo de Efectivo
2025-12-312024-12-312023-12-312022-12-312021-12-31
Flujo de caja libre $-40M$-65M$-87M$-36M$-68M

Últimas noticias Noticias recientes que mencionan a esta empresa

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Propietarios institucionales (13F) 191 declarantes · $496.0M total · A fecha de 30 de junio de 2026

Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.

Actividad institucional — Q2 2026 vs trimestre anterior
Nuevas posiciones Posiciones cerradas Aumentado Disminuido Cambio neto de acciones
41 (+15 vs trimestre anterior) 22 (-8 vs trimestre anterior) 55 (+10 vs trimestre anterior) 44 (-8 vs trimestre anterior) +14.8M

Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.

Institución Valor Acciones % de 13F rastreadas Tipo
Two Seas Capital LP $91 658 798 19 095 583 18,48% Acciones
Whitefort Capital Management, LP $75 812 453 15 794 261 15,28% Acciones
VANGUARD GROUP INC $38 412 670 7 986 002 7,74% Acciones
STATE STREET CORP $37 772 059 7 869 179 7,62% Acciones
Rubric Capital Management LP $36 158 098 7 532 937 7,29% Acciones
VANGUARD CAPITAL MANAGEMENT LLC $33 651 259 7 010 679 6,78% Acciones
GEODE CAPITAL MANAGEMENT, LLC $16 983 987 3 537 471 3,42% Acciones
BlackBarn Capital Partners LP $12 000 000 2 500 000 2,42% Acciones
Woodline Partners LP $10 952 909 2 281 856 2,21% Acciones
GOLDMAN SACHS GROUP INC $8 545 829 1 780 381 1,72% Acciones
Jefferies Financial Group Inc. $8 216 026 1 711 672 1,66% Acciones
NOMURA HOLDINGS INC $7 857 989 1 637 081 1,58% Acciones
VANGUARD PORTFOLIO MANAGEMENT LLC $7 398 998 1 541 458 1,49% Acciones
BANK OF AMERICA CORP /DE/ $7 169 851 1 493 719 1,45% Acciones
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $6 869 846 1 431 218 1,38% Acciones
OSAIC HOLDINGS, INC. $6 469 756 1 347 866 1,30% Acciones
ADAR1 Capital Management, LLC $6 087 106 1 268 147 1,23% Acciones
Deltroit Asset Management (UK) LLP $5 760 000 1 200 000 1,16% Acciones
VANGUARD FIDUCIARY TRUST CO $5 449 738 1 135 362 1,10% Acciones
CITIGROUP INC $4 175 784 869 955 0,84% Acciones
BANK OF MONTREAL /CAN/ $3 734 102 777 938 0,75% Acciones
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $3 123 360 650 700 0,63% Acciones
MACKENZIE FINANCIAL CORP $2 946 269 613 806 0,59% Acciones
LOS ANGELES CAPITAL MANAGEMENT LLC $2 889 638 602 008 0,58% Acciones
Western Standard LLC $2 605 378 542 787 0,53% Acciones
Rangeley Capital, LLC $2 400 000 500 000 0,48% Acciones
Man Group plc $2 272 642 473 467 0,46% Acciones
Corbin Capital Partners, L.P. $2 231 732 682 487 0,45% Acciones
CenterBook Partners LP $2 136 725 445 151 0,43% Acciones
Freestone Capital Holdings, LLC $2 124 000 442 500 0,43% Acciones
CITADEL ADVISORS LLC $1 942 541 404 696 0,39% Acciones
KENNEDY CAPITAL MANAGEMENT LLC $1 849 430 385 298 0,37% Acciones
Swiss National Bank $1 375 200 286 500 0,28% Acciones
Ledgewood Wealth Advisors, LLC $1 336 493 278 436 0,27% Acciones
FMR LLC $1 277 232 266 090 0,26% Acciones
Susquehanna Portfolio Strategies, LLC $1 265 688 263 685 0,26% Acciones
Carrera Capital Advisors $1 234 402 257 167 0,25% Acciones
Quinn Opportunity Partners LLC $1 225 027 255 214 0,25% Acciones
D. E. Shaw & Co., Inc. $1 209 614 252 003 0,24% Acciones
STATE OF WISCONSIN INVESTMENT BOARD $1 161 682 242 017 0,23% Acciones
Campbell & CO Investment Adviser LLC $1 106 563 230 534 0,22% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1 080 475 225 099 0,22% Acciones
Squarepoint Ops LLC $999 096 208 145 0,20% Acciones
MARTINGALE ASSET MANAGEMENT L P $926 880 193 100 0,19% Acciones
RHUMBLINE ADVISERS $909 224 189 423 0,18% Acciones
STRS OHIO $810 720 168 900 0,16% Acciones
Bank of New York Mellon Corp $801 067 166 889 0,16% Acciones
Caption Management, LLC $720 000 150 000 0,15% Opción de compra
Caption Management, LLC $720 000 150 000 0,15% Opción de venta
Hudson Bay Capital Management LP $720 000 150 000 0,15% Acciones
Wealth Management Associates, Inc. $710 376 147 995 0,14% Acciones
WELLINGTON MANAGEMENT GROUP LLP $701 467 146 139 0,14% Acciones
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $643 433 142 985 0,13% Acciones
ALLIANCEBERNSTEIN L.P. $631 080 140 240 0,13% Acciones
Connor, Clark & Lunn Investment Management Ltd. $619 685 129 101 0,12% Acciones
BlackRock, Inc. $567 398 118 208 0,11% Acciones
Front Row Advisors LLC $516 035 110 500 0,10% Acciones
BARCLAYS PLC $499 320 104 025 0,10% Acciones
Rafferty Asset Management, LLC $490 416 102 170 0,10% Acciones
MetLife Investment Management, LLC $452 885 94 351 0,09% Acciones
VANGUARD ASSET MANAGEMENT, Ltd $429 994 89 582 0,09% Acciones
TWO SIGMA INVESTMENTS, LP $407 933 84 986 0,08% Acciones
JBF Capital, Inc. $385 349 80 281 0,08% Acciones
Integrated Quantitative Investments LLC $383 698 79 937 0,08% Acciones
Virtus Investment Advisers, LLC $368 674 76 807 0,07% Acciones
XTX Topco Ltd $365 808 76 210 0,07% Acciones
AMERICAN CENTURY COMPANIES INC $317 832 66 215 0,06% Acciones
Invesco Ltd. $305 616 63 670 0,06% Acciones
Rockefeller Capital Management L.P. $302 400 63 000 0,06% Acciones
Creative Planning $298 133 62 111 0,06% Acciones
JANUS HENDERSON GROUP PLC $273 746 60 900 0,06% Acciones
Quantinno Capital Management LP $273 413 56 961 0,06% Acciones
Zurcher Kantonalbank (Zurich Cantonalbank) $265 118 55 233 0,05% Acciones
Vanguard Global Advisers, LLC $264 730 55 152 0,05% Acciones
Mitsubishi UFJ Asset Management Co., Ltd. $255 936 53 320 0,05% Acciones
Jump Financial, LLC $255 178 53 162 0,05% Acciones
PROFUND ADVISORS LLC $254 482 53 017 0,05% Acciones
WOLVERINE TRADING, LLC $248 868 55 800 0,05% Opción de compra
Police & Firemen's Retirement System of New Jersey $248 203 51 709 0,05% Acciones
Exome Asset Management LLC $240 797 50 166 0,05% Acciones
Magnetar Financial LLC $225 922 47 067 0,05% Acciones
State of New Jersey Common Pension Fund D $221 602 46 167 0,04% Acciones
MANUFACTURERS LIFE INSURANCE COMPANY, THE $212 664 44 305 0,04% Acciones
ALLSTATE CORP $212 285 44 226 0,04% Acciones
Quadrature Capital Ltd $201 619 42 004 0,04% Acciones
Universal- Beteiligungs- und Servicegesellschaft mbH $189 475 39 474 0,04% Acciones
ARIZONA STATE RETIREMENT SYSTEM $189 110 39 398 0,04% Acciones
SUSQUEHANNA INTERNATIONAL GROUP, LLP $175 680 36 600 0,04% Opción de compra
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $171 936 35 820 0,03% Acciones
NEW YORK STATE COMMON RETIREMENT FUND $169 286 35 268 0,03% Acciones
INTECH INVESTMENT MANAGEMENT LLC $167 208 34 835 0,03% Acciones
Mitsubishi UFJ Trust & Banking Corp $152 102 31 688 0,03% Acciones
VOYA INVESTMENT MANAGEMENT LLC $151 070 31 473 0,03% Acciones
China Universal Asset Management Co., Ltd. $150 902 31 438 0,03% Acciones
Vanguard Investments Australia, Ltd. $150 182 31 288 0,03% Acciones
KLP KAPITALFORVALTNING AS $148 320 30 900 0,03% Acciones
Premier Path Wealth Partners, LLC $144 000 30 000 0,03% Acciones
BNP PARIBAS FINANCIAL MARKETS $139 675 29 099 0,03% Acciones
SHERBROOKE PARK ADVISERS LLC $134 627 27 989 0,03% Acciones
EntryPoint Capital, LLC $134 112 27 940 0,03% Acciones

Informantes de la empresa 25 insiders · 13 directivos · 11 consejeros

Insider Rol Última actividad Acciones en propiedad Compras 12m Ventas 12m Neto 12m
William H. Collier President and CEO 24 de junio de 2019 A 0 0 $0
Mark J. Murray President and CEO 1 de marzo de 2019 A 341 396 0 0 $0
David C Hastings Chief Financial Officer 1 de marzo de 2019 A 0 0 $0
Bruce Cousins EVP & Chief Financial Officer 24 de marzo de 2017 A 0 0 $0
Gaston Picchio Chief Development Officer 1 de marzo de 2019 A 0 0 $0
Elizabeth Howard Executive VP & General Counsel 1 de marzo de 2019 A 0 0 $0
Michael J. Mcelhaugh Chief Business Officer 1 de marzo de 2019 A 0 0 $0
Michael J. Sofia Chief Scientific Officer 1 de marzo de 2019 A 1 503 403 0 0 $0
Koert Vandenenden Chief Accounting Officer 11 de diciembre de 2018 A 0 0 $0
William T. Symonds Chief Development Officer 16 de abril de 2018 A 0 0 $0
Peter Lutwyche Chief Technology Officer 24 de marzo de 2017 A 0 0 $0
Michael J. Abrams Managing Director 16 de agosto de 2016 M 42 097 0 0 $0
Mark Kowalski Sr VP & Chief Medical Officer 15 de marzo de 2016 A 0 0 $0
Roger Sawhney Consejero 8 de junio de 2026 A 0 0 $0
Robert A Beardsley Consejero 8 de junio de 2026 A 0 0 $0
Frank Torti Consejero 26 de noviembre de 2018 A 0 0 $0
Vivek Ramaswamy Consejero 19 de junio de 2018 A 0 0 $0
Keith S Manchester Consejero 19 de junio de 2018 A 0 0 $0
Daniel D Burgess Consejero 19 de junio de 2018 A 0 0 $0
Herbert J Conrad Consejero 19 de junio de 2018 A 0 0 $0
Richard C Henriques JR Consejero 19 de junio de 2018 A 1 000 0 0 $0
Frank Karbe Consejero 21 de junio de 2017 A 0 0 $0
Roivant Sciences Ltd. Propietario del 10% 18 de octubre de 2021 C 38 847 462 0 0 $0
Andrew Lo Propietario del 10% 12 de enero de 2018 P 0 0 $0
Patrick Machado Propietario del 10% 12 de enero de 2018 P 0 0 $0

Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto

Activistas y propietarios del %+ 5 8 tenencias

Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.

Declarante Presentado Participación Estado Propósito Presentación
Whitefort Capital Master Fund, LP, Whitefort Capital GP, LLC, Whitefort Capital Management, LP, Whitefort Capital Management GP, LLC, David Salanic, Joseph Kaplan ×5 presentaciones 28 de abril de 2026 8,00% Enmienda SEC
Roivant Sciences Ltd. ×14 presentaciones 25 de febrero de 2025 20,50% Enmienda SEC
Patrick Machado ×4 presentaciones 17 de julio de 2019 Presentación inicial SEC
Dr. Andrew Lo ×5 presentaciones 17 de julio de 2019 Presentación inicial SEC
QVT Financial LP, QVT Financial GP LLC, QVT Family Office Fund LP, QVT Associates GP LLC ×6 presentaciones 12 de julio de 2019 Presentación inicial SEC
SVF Investments (UK) Limited, SVF Holdings (UK) LLP, SoftBank Vision Fund L.P., SVF GP (Jersey) Limited ×4 presentaciones 12 de julio de 2019 Presentación inicial SEC
Dexxon Holdings Ltd., Dexcel Pharma Technologies Ltd., Dan Oren ×6 presentaciones 12 de julio de 2019 Presentación inicial SEC
Viking Global Investors LP, Viking Global Performance LLC, Viking Global Equities LP, Viking Global Equities II LP, VGE III Portfolio Ltd., Viking Global Equities Master Ltd., Viking Long Fund GP LLC, Viking Long Fund Master Ltd., Viking Global Opportunities GP LLC, Viking Global Opportunities Portfolio GP LLC, Viking Global Opportunities Illiquid Investments Sub-Master LP, O. Andreas Halvorsen, David C. Ott, Rose S. Shabet ×7 presentaciones 12 de julio de 2019 Presentación inicial SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Propiedad de ETFs Mantenido por 34 ETFs

El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.

Fondo Ponderación Unidades A fecha de Fuente
BBC · ETFis Series Trust I 0,66% 58 600 NS 30 de abril de 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0,50% 24 523 SH 8 de agosto de 2026 Diario
IWC · iShares Trust 0,17% 546 359 SH 8 de agosto de 2026 Diario
LABU · Direxion Shares ETF Trust 0,11% 132 235 NS 30 de abril de 2026 N-PORT
SMMV · iShares Trust 0,10% 62 236 SH 8 de agosto de 2026 Diario
IBBQ · Invesco Exchange-Traded Fund Trust … 0,06% 10 748 SH 8 de agosto de 2026 Diario
IBB · iShares Trust 0,06% 1 164 301 SH 8 de agosto de 2026 Diario
VTWG · VANGUARD SCOTTSDALE FUNDS 0,05% 172 487 SH 8 de agosto de 2026 Diario
IWO · iShares Trust 0,04% 1 441 824 SH 8 de agosto de 2026 Diario
BIB · ProShares Trust 0,04% 7 110 NS 31 de mayo de 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0,03% 64 366 NS 31 de mayo de 2026 N-PORT
IWM · iShares Trust 0,02% 4 026 921 SH 8 de agosto de 2026 Diario
VTWO · VANGUARD SCOTTSDALE FUNDS 0,02% 925 044 SH 8 de agosto de 2026 Diario
PRFZ · Invesco Exchange-Traded Fund Trust 0,02% 122 366 SH 8 de agosto de 2026 Diario
RSSL · Global X Funds 0,02% 65 520 NS 30 de abril de 2026 N-PORT
ITWO · ProShares Trust 0,02% 7 126 NS 31 de mayo de 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0,01% 734 401 NS 31 de mayo de 2026 N-PORT
ISCG · iShares Trust 0,01% 24 628 SH 8 de agosto de 2026 Diario
ISCB · iShares Trust 0,01% 6 673 SH 8 de agosto de 2026 Diario
UWM · ProShares Trust 0,01% 5 554 NS 31 de mayo de 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0,01% 1 810 587 SH 8 de agosto de 2026 Diario
VHT · VANGUARD WORLD FUND 0,01% 430 244 SH 8 de agosto de 2026 Diario
FHLC · FIDELITY COVINGTON TRUST 0,01% 64 437 NS 30 de abril de 2026 N-PORT
ISCV · iShares Trust 0,01% 13 314 SH 8 de agosto de 2026 Diario
WSML · iShares Trust 0,01% 11 503 SH 8 de agosto de 2026 Diario
URTY · ProShares Trust 0,01% 5 639 NS 31 de mayo de 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,00% 5 309 NS 31 de mayo de 2026 N-PORT
HDG · ProShares Trust 0,00% 141 NS 31 de mayo de 2026 N-PORT
ITOT · iShares Trust 0,00% 266 009 SH 8 de agosto de 2026 Diario
IWV · iShares Trust 0,00% 49 253 SH 8 de agosto de 2026 Diario
SCHB · SCHWAB STRATEGIC TRUST 0,00% 86 163 NS 31 de mayo de 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0,00% 4 760 NS 31 de mayo de 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0,00% 5 034 547 SH 8 de agosto de 2026 Diario
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 13 683 SH 8 de agosto de 2026 Diario