SLDB — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $120 240 899 | 12 036 126 | 10,43% | Actions |
| PERCEPTIVE ADVISORS LLC | $118 947 393 | 11 906 646 | 10,31% | Actions |
| Bain Capital Life Sciences Investors, LLC | $97 990 102 | 9 808 819 | 8,50% | Actions |
| Siren, L.L.C. | $76 827 146 | 7 690 405 | 6,66% | Actions |
| BlackRock, Inc. | $69 273 136 | 6 934 248 | 6,01% | Actions |
| FMR LLC | $68 690 808 | 6 875 957 | 5,96% | Actions |
| ARMISTICE CAPITAL, LLC | $42 737 220 | 4 278 000 | 3,71% | Actions |
| STATE STREET CORP | $41 711 896 | 4 175 365 | 3,62% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $40 059 121 | 4 009 922 | 3,47% | Actions |
| RTW INVESTMENTS, LP | $38 890 331 | 3 892 926 | 3,37% | Actions |
| Deep Track Capital, LP | $35 614 969 | 3 565 062 | 3,09% | Actions |
| FRANKLIN RESOURCES INC | $34 372 673 | 3 440 708 | 2,98% | Actions |
| JANUS HENDERSON GROUP PLC | $28 877 004 | 4 010 695 | 2,50% | Actions |
| CITADEL ADVISORS LLC | $28 123 069 | 2 815 122 | 2,44% | Actions |
| Alyeska Investment Group, L.P. | $22 782 035 | 2 280 484 | 1,98% | Actions |
| AMERIPRISE FINANCIAL INC | $22 235 593 | 2 225 783 | 1,93% | Actions |
| Vestal Point Capital, LP | $21 578 400 | 2 160 000 | 1,87% | Actions |
| VANGUARD GROUP INC | $19 485 969 | 3 454 959 | 1,69% | Actions |
| Redmile Group, LLC | $19 467 463 | 1 948 695 | 1,69% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $19 391 710 | 1 940 824 | 1,68% | Actions |
| GOLDMAN SACHS GROUP INC | $16 013 141 | 1 602 917 | 1,39% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $15 049 995 | 1 506 506 | 1,30% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $12 645 298 | 1 266 290 | 1,10% | Actions |
| BLAIR WILLIAM & CO/IL | $7 555 207 | 756 277 | 0,66% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $7 478 404 | 748 589 | 0,65% | Actions |
| Woodline Partners LP | $6 734 019 | 674 076 | 0,58% | Actions |
| SILVERARC CAPITAL MANAGEMENT, LLC | $6 677 816 | 668 450 | 0,58% | Actions |
| Birchview Capital, LP | $6 655 298 | 666 196 | 0,58% | Actions |
| NORTHERN TRUST CORP | $6 030 434 | 603 647 | 0,52% | Actions |
| MOORE CAPITAL MANAGEMENT, LP | $6 028 685 | 603 472 | 0,52% | Actions |
| BANK OF AMERICA CORP /DE/ | $5 235 779 | 524 102 | 0,45% | Actions |
| Monashee Investment Management LLC | $4 995 000 | 500 000 | 0,43% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $4 942 353 | 494 730 | 0,43% | Actions |
| Point72 Asset Management, L.P. | $4 475 600 | 448 008 | 0,39% | Actions |
| STEMPOINT CAPITAL LP | $3 584 212 | 358 780 | 0,31% | Actions |
| Boxer Capital Management, LLC | $2 997 000 | 300 000 | 0,26% | Actions |
| JPMORGAN CHASE & CO | $2 667 443 | 281 673 | 0,23% | Actions |
| Ally Bridge Group (NY) LLC | $2 557 030 | 255 959 | 0,22% | Actions |
| MORGAN STANLEY | $2 549 403 | 255 195 | 0,22% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2 441 566 | 244 401 | 0,21% | Actions |
| Bank of New York Mellon Corp | $2 429 105 | 243 154 | 0,21% | Actions |
| J. Goldman & Co LP | $2 419 218 | 242 164 | 0,21% | Actions |
| Nuveen, LLC | $2 414 004 | 241 642 | 0,21% | Actions |
| D. E. Shaw & Co., Inc. | $2 225 662 | 222 789 | 0,19% | Actions |
| UBS Group AG | $1 881 587 | 188 347 | 0,16% | Actions |
| ALGERT GLOBAL LLC | $1 872 316 | 187 419 | 0,16% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $1 851 797 | 185 365 | 0,16% | Actions |
| Balyasny Asset Management L.P. | $1 780 747 | 178 253 | 0,15% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 628 740 | 163 037 | 0,14% | Actions |
| Apis Capital Advisors, LLC | $1 598 400 | 160 000 | 0,14% | Actions |
| Soleus Capital Management, L.P. | $1 498 500 | 150 000 | 0,13% | Actions |
| CITIGROUP INC | $1 482 836 | 148 432 | 0,13% | Actions |
| Invesco Ltd. | $1 432 936 | 143 437 | 0,12% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $1 369 479 | 137 085 | 0,12% | Actions |
| Qube Research & Technologies Ltd | $1 367 661 | 136 903 | 0,12% | Actions |
| Y-Intercept (Hong Kong) Ltd | $1 097 761 | 109 886 | 0,10% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $1 081 038 | 108 212 | 0,09% | Actions |
| Susquehanna Portfolio Strategies, LLC | $1 071 717 | 107 279 | 0,09% | Actions |
| RHUMBLINE ADVISERS | $1 049 627 | 105 068 | 0,09% | Actions |
| Fisher Asset Management, LLC | $1 033 775 | 103 481 | 0,09% | Actions |
| GOLDMAN SACHS GROUP INC | $999 000 | 100 000 | 0,09% | Option d'achat |
| ALPS ADVISORS INC | $998 161 | 99 916 | 0,09% | Actions |
| XTX Topco Ltd | $889 450 | 89 034 | 0,08% | Actions |
| Jump Financial, LLC | $880 628 | 88 151 | 0,08% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $820 179 | 82 100 | 0,07% | Actions |
| Verition Fund Management LLC | $811 937 | 81 275 | 0,07% | Actions |
| Quadrature Capital Ltd | $782 117 | 78 290 | 0,07% | Actions |
| DEUTSCHE BANK AG\ | $774 644 | 77 542 | 0,07% | Actions |
| Quantum Private Wealth, LLC | $738 241 | 73 898 | 0,06% | Actions |
| Rafferty Asset Management, LLC | $717 072 | 71 779 | 0,06% | Actions |
| Trexquant Investment LP | $690 589 | 69 128 | 0,06% | Actions |
| WELLS FARGO & COMPANY/MN | $686 942 | 68 763 | 0,06% | Actions |
| BARCLAYS PLC | $649 380 | 65 003 | 0,06% | Actions |
| AMERICAN CENTURY COMPANIES INC | $621 488 | 62 211 | 0,05% | Actions |
| JANE STREET GROUP, LLC | $617 242 | 61 786 | 0,05% | Actions |
| TWO SIGMA INVESTMENTS, LP | $606 443 | 60 705 | 0,05% | Actions |
| DeepCurrents Investment Group LLC | $591 139 | 59 173 | 0,05% | Actions |
| Vanguard Global Advisers, LLC | $585 324 | 58 591 | 0,05% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $575 604 | 57 618 | 0,05% | Actions |
| Knott David M Jr | $561 518 | 56 208 | 0,05% | Actions |
| ALLIANCEBERNSTEIN L.P. | $498 672 | 69 260 | 0,04% | Actions |
| Russell Investments Group, Ltd. | $482 516 | 48 300 | 0,04% | Actions |
| BANK OF NOVA SCOTIA | $471 538 | 47 201 | 0,04% | Actions |
| MetLife Investment Management, LLC | $461 108 | 46 157 | 0,04% | Actions |
| Virtus Investment Advisers, LLC | $457 802 | 45 826 | 0,04% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $440 959 | 44 574 | 0,04% | Actions |
| Ikarian Capital, LLC | $429 130 | 42 956 | 0,04% | Actions |
| Quantinno Capital Management LP | $400 999 | 40 140 | 0,03% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $373 626 | 37 400 | 0,03% | Option d'achat |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $368 831 | 36 920 | 0,03% | Actions |
| PROFUND ADVISORS LLC | $365 065 | 36 543 | 0,03% | Actions |
| Creative Planning | $358 241 | 35 860 | 0,03% | Actions |
| CIBC Bancorp USA Inc. | $349 411 | 34 976 | 0,03% | Actions |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | $332 577 | 33 291 | 0,03% | Actions |
| ArchPoint Investors | $312 947 | 31 326 | 0,03% | Actions |
| CITADEL ADVISORS LLC | $308 691 | 30 900 | 0,03% | Option d'achat |
| Engineers Gate Manager LP | $288 861 | 28 915 | 0,03% | Actions |
| HSBC HOLDINGS PLC | $285 269 | 27 804 | 0,02% | Actions |
| Atom Investors LP | $271 548 | 27 182 | 0,02% | Actions |
| Police & Firemen's Retirement System of New Jersey | $231 868 | 23 210 | 0,02% | Actions |
| SFMG, LLC | $221 308 | 22 153 | 0,02% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $212 218 | 21 243 | 0,02% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $199 291 | 19 949 | 0,02% | Actions |
| AXQ CAPITAL, LP | $197 193 | 19 739 | 0,02% | Actions |
| CIBC Private Wealth Group LLC | $188 802 | 30 600 | 0,02% | Actions |
| Skopos Labs, Inc. | $185 840 | 25 811 | 0,02% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $169 830 | 17 000 | 0,01% | Actions |
| INTECH INVESTMENT MANAGEMENT LLC | $162 857 | 16 302 | 0,01% | Actions |
| Lido Advisors, LLC | $159 700 | 15 986 | 0,01% | Actions |
| China Universal Asset Management Co., Ltd. | $156 523 | 15 668 | 0,01% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $156 084 | 15 624 | 0,01% | Actions |
| INCEPTIONR LLC | $150 819 | 15 097 | 0,01% | Actions |
| ProShare Advisors LLC | $135 166 | 13 530 | 0,01% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $132 867 | 13 300 | 0,01% | Option de vente |
| SEI INVESTMENTS CO | $130 649 | 13 078 | 0,01% | Actions |
| PRUDENTIAL FINANCIAL INC | $129 520 | 12 965 | 0,01% | Actions |
| LPL Financial LLC | $127 882 | 12 801 | 0,01% | Actions |
| US BANCORP \DE\ | $122 637 | 12 276 | 0,01% | Actions |
| LMR Partners LLP | $112 857 | 11 297 | 0,01% | Actions |
| E Fund Management Co., Ltd. | $101 109 | 10 121 | 0,01% | Actions |
| Quantbot Technologies LP | $96 254 | 9 635 | 0,01% | Actions |
| SIMPLEX TRADING, LLC | $92 757 | 9 285 | 0,01% | Actions |
| Legal & General Group Plc | $76 314 | 7 639 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $71 349 | 7 142 | 0,01% | Actions |
| ROYAL BANK OF CANADA | $61 000 | 6 057 | 0,01% | Actions |
| Farther Finance Advisors, LLC | $54 980 | 5 531 | 0,00% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $54 306 | 5 436 | 0,00% | Actions |
| Arax Advisory Partners | $51 019 | 5 107 | 0,00% | Actions |
| Steward Partners Investment Advisory, LLC | $49 500 | 4 955 | 0,00% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $43 986 | 4 403 | 0,00% | Actions |
| GROUP ONE TRADING LLC | $42 258 | 4 230 | 0,00% | Actions |
| CWM, LLC | $38 124 | 5 295 | 0,00% | Actions |
| Tower Research Capital LLC (TRC) | $26 923 | 2 695 | 0,00% | Actions |
| Rockefeller Capital Management L.P. | $19 451 | 1 947 | 0,00% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $19 441 | 1 946 | 0,00% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $15 358 | 2 133 | 0,00% | Actions |
| GAMMA Investing LLC | $14 156 | 1 417 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $13 206 | 1 322 | 0,00% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $10 829 | 1 084 | 0,00% | Actions |
| Sterling Capital Management LLC | $9 481 | 949 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $8 561 | 857 | 0,00% | Actions |
| PNC Financial Services Group, Inc. | $6 813 | 682 | 0,00% | Actions |
| Larson Financial Group LLC | $6 434 | 644 | 0,00% | Actions |
| True Wealth Design, LLC | $5 635 | 564 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $5 624 | 563 | 0,00% | Actions |
| Physician Wealth Advisors, Inc. | $3 117 | 312 | 0,00% | Actions |
| IFP Advisors, Inc | $2 977 | 298 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $2 827 | 283 | 0,00% | Actions |
| Optiver Holding B.V. | $2 637 | 264 | 0,00% | Actions |
| Essential Partners LLC | $2 627 | 263 | 0,00% | Actions |
| EASTERN BANK | $1 508 | 151 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $1 499 | 150 | 0,00% | Actions |
| Parkside Financial Bank & Trust | $1 349 | 135 | 0,00% | Actions |
| Parallel Advisors, LLC | $1 249 | 125 | 0,00% | Actions |
| Versant Capital Management, Inc | $774 | 107 | 0,00% | Actions |
| Fortitude Family Office, LLC | $769 | 77 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $646 | 64 637 | 0,00% | Actions |
| Stone House Investment Management, LLC | $410 | 41 | 0,00% | Actions |
| Keating Financial Advisory Services, Inc. | $330 | 33 | 0,00% | Actions |
| NATIONAL BANK OF CANADA /FI/ | $309 | 31 | 0,00% | Actions |
| SG Americas Securities, LLC | $161 | 16 136 | 0,00% | Actions |
| Clearstead Advisors, LLC | $60 | 6 | 0,00% | Actions |
| Pacer Advisors, Inc. | $12 | 1 199 | 0,00% | Actions |
| HANTZ FINANCIAL SERVICES, INC. | $10 | 1 000 | 0,00% | Actions |