ZYME Cuplikan Saham Harga, kapitalisasi pasar, P/E, EPS, ROE, utang/ekuitas, kisaran 52 minggu

03

Harga $25.15

Kapitalisasi Pasar (MRQ) $1.80B

P/E (TTM) -12.5

EPS (TTM) $-2.02

Pendapatan (TTM) $37M

ROE (TTM) -72.3%

Rentang 52M $16–$31

ZYME Grafik Harga Saham OHLCV harian dengan indikator teknis — geser, perbesar, dan sesuaikan tampilan Anda

04

rentang

batang

Granularitas batang menyesuaikan dengan periode yang dipilih — arahkan kursor ke bagan untuk melihat buka/tinggi/rendah/tutup untuk sebuah batang.

Tentang Zymeworks Inc. - Common Stock Tinjauan perusahaan dari Wikipedia

05 · wikidata

Zymeworks Inc. is a publicly held biotechnology company based in Vancouver,

British Columbia, that develops protein therapeutics for the treatment of cancer as well as for autoimmune and inflammatory diseases. The products are based upon the company's molecular modeling software for optimizing protein structure. In 2014, Zymeworks raised $44 million across various funding rounds according to PitchBook, placing it among the top 10 HealthTech businesses in the world to raise the most capital that year. In May 2017, Zymeworks held an IPO on the Toronto Stock Exchange, raising $59 million. This was the largest Canadian biotech IPO in more than a decade. By alphabetical order, Zymeworks is the last company on the Toronto Stock Exchange.

In May 2019, Zymeworks announced that GSK has expanded its 2016 licensing and collaboration agreement for the research, development and commercialization of bispecific antibodies across multiple disease areas. The extended agreement has meant that GSK can have access to Zymeworks' heavy-light chain pairing technology, which enables the development of bispecific and multifunctional therapeutics.

In September 2019, Zymeworks announced that, following their clinical trials, it has been confirmed that their ZW25 monotherapy can provide durable disease control in patients with a variety of HER2-expressing solid tumors that have progressed following standard of care treatments.

In May 2022, Zymeworks rejected an unsolicited takeover proposal from a Dubai hedge fund, All Blue Falcons FZE, an arm of All Blue Capital.

Azymetric

This is an IgG1-based heterodimeric antibody scaffold that consists of two different heavy chains engineered to exclusively assemble into a single molecule, allowing bi-specific binding to two different antigens or drug targets. The Azymetric scaffold is engineered by making amino acid changes in the CH3 region of the constant Fc domain of the IgG1. This scaffold can also be engineered with tailored effector function and optimized serum half-life.

Awards and recognition

Deal of the Year, Lifesciences BC Awards, 2018

Life Sciences Company of the Year, Lifesciences BC Awards, 2016

Emerging company of the year – Health, BIOTECanada Gold Leaf Awards, 2015

12th Place, BC's Leading Innovators, 2011

Life Science Emerging Rocket, 2009, 2010, 2011

Early stage Company of the year – Industrial & Agriculture, BIOTECanada Gold Leaf Awards, 2009

== References ==

Baca selengkapnya Tampilkan lebih sedikit

Sumber: Wikipedia (English), CC BY-SA 4.0 · Lihat di Wikipedia ↗

Wikidata ↗

sektorHealthcare industriBiotechnology karyawan231 negaraUS

Kinerja 10 Tahun Tren Pendapatan, laba bersih, margin, dan EPS

06

Pendapatan$106M

2020-12-31 → 2025-12-31

EPS$-1.08

2020-12-31 → 2025-12-31

Arus Kas Bebas$-35M

2023-12-31 → 2025-12-31

Margin bersih-404.0%

2023-12-31 → 2025-12-31

Valuasi & Rasio 07–12

Valuasi Rasio P/E, P/S, P/B, EV/EBITDA — apakah sahamnya mahal atau murah?

Metrik	ZYME	rata-rata 5T	Median Rekan	Kesimpulan
P/E (TTM)	-12.5rata-rata 5T ≈-8.8	≈-8.8	·	·
P/S (TTM)	48.4rata-rata 5T ≈13.8	≈13.8	10.3	Terlalu mahal
P/B (MRQ)	22.3rata-rata 5T ≈4.0	≈4.0	3.7	Terlalu mahal
Harga / FCF (TTM)	-14.9rata-rata 5T ≈-24.0	≈-24.0	·	·
Harga / Arus Kas (TTM)	-15.0rata-rata 5T ≈-25.0	≈-25.0	·	·
Harga / Nilai Buku Berwujud (MRQ)	22.6rata-rata 5T ≈3.4	≈3.4	·	·

Median rekan dihitung berdasarkan basis standar per metrik dan mungkin tidak selalu cocok dengan basis TTM/MRQ yang ditampilkan untuk saham ini.

Profitabilitas Margin kotor, operasional, dan bersih; ROE, ROA, ROIC

Metrik	ZYME	rata-rata 5T	Median Rekan	Kesimpulan
Margin Operasi (TTM)	-419.0%rata-rata 5T ≈-149.5%	≈-149.5%	-588.2%	Lemah
EBITDA Margin (Margin EBITDA)	-87.3%rata-rata 5T ≈-149.5%	≈-149.5%	-588.2%	Lemah
Margin Sebelum Pajak (TTM)	-407.8%rata-rata 5T ≈-128.3%	≈-128.3%	-709.2%	Lemah
Margin Laba Bersih (TTM)	-404.0%rata-rata 5T ≈-131.2%	≈-131.2%	-507.2%	Lemah
ROA (TTM)	-37.2%rata-rata 5T ≈-21.0%	≈-21.0%	-29.6%	Tingkat teratas
ROE (TTM)	-72.3%rata-rata 5T ≈-29.5%	≈-29.5%	-42.0%	Tingkat teratas
ROIC	-35.1%rata-rata 5T ≈-35.7%	≈-35.7%	·	·

Kesehatan Keuangan Utang, likuiditas, solvabilitas — kekuatan neraca

Metrik	Tren 5 Tahun	ZYME	rata-rata 5T	Median Rekan	Kesimpulan
Rasio Lancar (MRQ)		6.3rata-rata 5T ≈5.6	≈5.6	9.0	Likuiditas rendah
Quick Ratio (Rasio Cepat)		1.1rata-rata 5T ≈3.2	≈3.2	5.8	Likuiditas rendah

Pertumbuhan Pertumbuhan Pendapatan, EPS, dan Laba Bersih: YoY, CAGR 3T, CAGR 5T

Metrik	ZYME	rata-rata 5T	Median Rekan	Kesimpulan
Revenue YoY (Pendapatan YoY)	38.9%rata-rata 5T ≈274.4%	≈274.4%	·	·
Revenue CAGR 3Y (CAGR Pendapatan 3T)	-36.4%rata-rata 5T ≈10.2%	≈10.2%	·	·
Revenue CAGR 5Y (CAGR Pendapatan 5T)	22.2%	·	·	·

Metrik Per Saham EPS, nilai buku per saham, arus kas per saham, dividen per saham

Metrik	ZYME	rata-rata 5T	Median Rekan	Kesimpulan
EPS (Diluted)	$-1.08rata-rata 5T ≈$-1.43	≈$-1.43	·	·
Revenue / Share (Pendapatan / Saham)	$1.41rata-rata 5T ≈$1.17	≈$1.17	·	·
Cash Flow / Share (Arus Kas / Saham)	$-0.44rata-rata 5T ≈$-1.20	≈$-1.20	·	·
Cash / Share (Kas / Saham)	$0.55rata-rata 5T ≈$1.25	≈$1.25	·	·

Efisiensi Modal Perputaran aset, perputaran persediaan, perputaran piutang

Metrik	ZYME	rata-rata 5T	Median Rekan	Kesimpulan
Asset Turnover (Perputaran Aset)	0.3rata-rata 5T ≈0.2	≈0.2	0.2	Tingkat teratas
Receivables Turnover (Perputaran Piutang)	3.5rata-rata 5T ≈2.8	≈2.8	·	·
Revenue / Employee (Pendapatan Tahunan ÷ karyawan (jumlah karyawan, yfinance). Turunan — bukan konsep SEC-XBRL yang tersimpan.)	≈$458.7K	·	·	·

nilai · ≈ rata-rata 5T · median industri · penilaian relatif terhadap median

Riwayat Pendapatan EPS aktual vs perkiraan, kejutan %, tingkat keberhasilan, tanggal pendapatan berikutnya

14

Kejutan Rata-rata -16.9%

Laporan Berikutnya Nov 04, 2026

Periode	Laporan	EPS Aktual	EPS Estimasi	Kejutan
30 Juni 2026	Agu 5, 2026	$-0.62	$-0.50	-25.1%
31 Maret 2026	Mei 6, 2026	$-0.59	$-0.20	-201.3%
31 Des. 2025		$-0.55	$-0.42	-29.5%
30 Sep. 2025		$-0.26	$-0.33	20.6%
30 Juni 2025		$0.03	$-0.50	106.0%
31 Maret 2025		$-0.30	$-0.42	28.0%

Fundamental Lengkap Semua metrik per tahun — laporan laba rugi, neraca, arus kas

15

Laporan Laba Rugi 14

Metrik	2025	2024	2023	2022	2021
Revenue	$106M	$76M	$76M	$412M	$27M
R&D Expense	·	·	$144M	$209M	$200M
SG&A Expense	$62M	$62M	$70M	$73M	$43M
Operating Expenses	$199M	$213M	$214M	$282M	$242M
Operating Income	$-93M	$-137M	$-138M	$131M	$-216M
Other Non-op	$51.0K	$-218.0K	$291.0K	$-42.0K	$118.0K
Pretax Income	$-80M	$-117M	$-119M	$135M	$-212M
Income Tax	$1M	$6M	$-568.0K	$11M	$-516.0K
Net Income	$-81M	$-123M	$-119M	$124M	$-212M
EPS (Basic)	$-1.08	$-1.62	$-1.72	$1.91	$-4.11
EPS (Diluted)	$-1.08	$-1.62	$-1.72	$1.90	$-4.61
Shares (Basic)	75,404,897	75,846,681	68,863,010	65,194,775	51,553,869
Shares (Diluted)	75,413,396	75,878,738	68,863,010	65,249,184	52,131,596
EBITDA	$-93M	$-137M	$-138M	·	·

Neraca 23

Metrik	2025	2024	2023	2022	2021
Cash & Equivalents	$41M	$66M	$158M	$401M	$202M
Short-term Investments	·	·	$217M	$91M	$51M
Receivables	$5M	$56M	$19M	$33M	$16M
Prepaid Expense	$15M	$19M	$19M	$19M	$20M
Current Assets	$249M	$300M	$413M	$545M	$288M
PP&E (Net)	$16M	$18M	$20M	$25M	$23M
PP&E (Gross)	$36M	$35M	$41M	$38M	$37M
Accum. Depreciation	$21M	$18M	$21M	$13M	$14M
Goodwill	$12M	$12M	$12M	$12M	$12M
Intangibles	$1M	$5M	$8M	$9M	$4M
Total Assets	$347M	$463M	$581M	$649M	$389M
Accounts Payable	$36M	$60M	$46M	$87M	$63M
Current Liabilities	$42M	$88M	$56M	$96M	$72M
Capital Leases	$15M	$16M	$22M	$25M	$31M
Deferred Tax	$6M	$5M	$3M	$2M	$2M
Other Non-current Liabilities	$278.0K	$923.0K	$2M	$3M	$3M
Total Liabilities	$78M	$124M	$116M	$156M	$140M
Common Stock	$1.11B	$1.02B	$997M	$886M	$741M
Retained Earnings	$-953M	$-830M	$-677M	$-559M	$-683M
AOCI	$-6M	$-7M	$-7M	$-7M	$-7M
Stockholders' Equity	$269M	$339M	$465M	$493M	$249M
Liabilities + Equity	$347M	$463M	$581M	$649M	$389M
Shares Outstanding	74,638,413	68,964,319	70,115,997	63,059,501	46,633,935

Arus Kas 14

Metrik	2025	2024	2023	2022	2021
Stock-based Comp	$28M	$18M	$8M	$4M	$11M
Deferred Tax	$945.0K	$691.0K	$-757.0K	$2M	$-953.0K
Amort. of Intangibles	$4M	$4M	$3M	$1M	$3M
Restructuring	·	·	$0	·	·
Operating Cash Flow	$-33M	$-110M	$-118M	$144M	$-192M
CapEx	$2M	$2M	$2M	$8M	$12M
Investing Cash Flow	$27M	$39M	$-207M	$-54M	$145M
Stock Issued	$0	$0	$26M	$108M	$0
Stock Repurchased	$42M	$30M	$0	$0	·
Net Stock Activity	$-42M	$-30M	$26M	·	·
Financing Cash Flow	$-19M	$-20M	$82M	$109M	$8M
Net Change in Cash	$-25M	$-91M	$-243M	$199M	$-40M
Taxes Paid	$1M	$3M	$165.0K	$10M	·
Free Cash Flow	$-35M	$-112M	$-121M	·	·

Profitabilitas 7

Metrik	2025	2024	2023	2022	2021
Operating Margin	-87.3%	-179.7%	-181.6%	·	·
Net Margin	-76.6%	-160.8%	-156.1%	·	·
Pretax Margin	-75.3%	-152.8%	-156.9%	·	·
EBITDA Margin	-87.3%	-179.7%	-181.6%	·	·
ROA	-20.0%	-23.5%	-19.3%	·	·
ROE	-26.9%	-34.8%	-26.7%	·	·
ROIC	-35.1%	-42.6%	-29.6%	·	·

Likuiditas & Solvabilitas 2

Metrik	Tren	2025	2024	2023	2022	2021
Current Ratio		5.9	3.4	7.4	·	·
Quick Ratio		1.1	1.4	7.1	·	·

Efisiensi 2

Metrik	Tren	2025	2024	2023	2022	2021
Asset Turnover		0.3	0.1	0.1	·	·
Receivables Turnover		3.5	2.0	2.9	·	·

Per Saham 5

Metrik	2025	2024	2023	2022	2021
Book Value / Share	$3.60	$4.91	$6.63	·	·
Revenue / Share	$1.41	$1.01	$1.10	·	·
Cash Flow / Share	$-0.44	$-1.45	$-1.72	·	·
Cash / Share	$0.55	$0.96	$2.25	·	·
EPS (TTM)	$-1.08	$-1.62	$-1.72	$1.90	·

Tingkat Pertumbuhan 3

Metrik	2025	2024	2023	2022	2021
Revenue YoY	38.9%	0.38%	-81.6%	1446.0%	-31.5%
Revenue CAGR 3Y	-36.4%	41.9%	25.0%	·	·
Revenue CAGR 5Y	22.2%	·	·	·	·

Valuasi (TTM) 10

Metrik	2025	2024	2023	2022	2021
Revenue TTM	$106M	$76M	$76M	$412M	·
Net Income TTM	$-81M	$-123M	$-119M	$124M	·
Market Cap	$1.97B	$1.01B	$729M	·	·
P/E	-24.4	-9.0	-6.0	4.1	·
P/S	18.5	13.2	9.6	·	·
P/B	7.3	3.0	1.6	·	·
P / Tangible Book	7.7	3.1	1.6	1.0	·
P / Cash Flow	-59.5	-9.2	-6.2	·	·
P / FCF	-56.9	-9.0	-6.0	·	·
Earnings Yield	-4.1%	-11.1%	-16.6%	24.2%	·

Laporan Laba Rugi 14

Metrik	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Revenue	$5M	$2M	$3M	$28M	$49M	$27M	$31M	$16M	$19M	$10M	$17M	$17M	$7M	$36M	$402M	$3M
R&D Expense	·	·	·	·	·	·	·	·	·	$32M	·	$33M	$39M	$46M	·	$37M
SG&A Expense	$19M	$15M	$15M	$14M	$15M	$17M	$16M	$14M	$16M	$16M	$15M	$17M	$22M	$17M	$30M	$16M
Operating Expenses	$47M	$50M	$47M	$50M	$49M	$53M	$53M	$50M	$62M	$48M	$40M	$50M	$61M	$63M	$83M	$53M
Operating Income	$-42M	$-47M	$-44M	$-22M	$-674.0K	$-26M	$-22M	$-34M	$-43M	$-38M	$-23M	$-33M	$-54M	$-27M	$319M	$-50M
Other Non-op	$196.0K	$120.0K	$-18.0K	$26.0K	$-621.0K	$49.0K	$-253.0K	$-37.0K	$53.0K	$19.0K	$-278.0K	$370.0K	$230.0K	$-31.0K	$-27.0K	$-98.0K
Pretax Income	$-45M	$-46M	$-41M	$-18M	$2M	$-22M	$-18M	$-30M	$-38M	$-32M	$-19M	$-28M	$-49M	$-23M	$320M	$-48M
Income Tax	$-273.0K	$-2M	$-270.0K	$1M	$-186.0K	$496.0K	$6M	$226.0K	$68.0K	$75.0K	$-5M	$1M	$2M	$1M	$11M	$-29.0K
Net Income	$-45M	$-44M	$-41M	$-20M	$2M	$-23M	$-24M	$-30M	$-38M	$-32M	$-14M	$-29M	$-51M	$-24M	$309M	$-48M
EPS (Basic)	$-0.62	$-0.59	$-0.55	$-0.26	$0.03	$-0.30	$-0.32	$-0.39	$-0.49	$-0.42	$-0.19	$-0.41	$-0.76	$-0.36	$4.78	$-0.72
EPS (Diluted)	$-0.62	$-0.59	$-0.55	$-0.26	$0.03	$-0.30	$-0.32	$-0.39	$-0.49	$-0.42	$-0.18	$-0.41	$-0.76	$-0.37	$4.78	$-0.72
Shares (Basic)	72,993,313	74,668,790	·	75,767,778	75,337,168	75,171,020	·	76,128,531	76,392,593	76,214,833	·	70,575,773	67,281,028	66,739,308	·	66,477,016
Shares (Diluted)	72,993,313	74,694,762	·	75,775,214	77,378,449	75,226,387	·	76,157,101	76,396,217	76,248,158	·	70,575,773	67,284,511	66,742,030	·	66,478,157
EBITDA	$-42M	$-47M	·	$-22M	$-674.0K	$-26M	·	$-34M	$-43M	$-38M	·	$-33M	$-54M	$-27M	·	$-50M

Neraca 23

Metrik	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Cash & Equivalents	$179M	$244M	$41M	$65M	$98M	$76M	$66M	$122M	$71M	$115M	·	$94M	$142M	$182M	·	$96M
Short-term Investments	·	·	·	·	·	·	·	·	·	·	·	$201M	$198M	$159M	·	$70M
Receivables	$6M	$5M	$5M	$29M	$3M	$25M	$56M	$24M	$32M	$31M	·	$67M	$49M	$67M	·	$7M
Prepaid Expense	$22M	$16M	$15M	$10M	$12M	$17M	$19M	$23M	$21M	$18M	·	$12M	$31M	$19M	·	$18M
Current Assets	$298M	$386M	$249M	$292M	$296M	$306M	$300M	$344M	$383M	$394M	·	$375M	$420M	$426M	·	$191M
PP&E (Net)	$14M	$15M	$16M	$16M	$16M	$17M	$18M	$18M	$18M	$19M	·	$21M	$22M	$24M	·	$26M
PP&E (Gross)	·	·	$36M	·	·	·	$35M	·	·	·	·	·	·	·	·	·
Accum. Depreciation	·	·	$21M	·	·	·	$18M	·	·	·	·	·	·	·	·	·
Goodwill	$12M	$12M	$12M	$12M	$12M	$12M	$12M	$12M	$12M	$12M	·	$12M	$12M	$12M	·	$12M
Intangibles	$998.0K	$1M	$1M	$1M	$2M	$3M	$5M	$6M	$7M	$7M	·	$8M	$7M	$8M	·	$9M
Total Assets	$397M	$478M	$347M	$397M	$408M	$426M	$463M	$487M	$516M	$554M	·	$556M	$602M	$601M	·	$300M
Accounts Payable	$27M	$30M	$36M	$34M	$31M	$38M	$60M	$52M	$44M	$47M	·	$68M	$70M	$59M	·	$52M
Current Liabilities	$47M	$36M	$42M	$42M	$39M	$65M	$88M	$84M	$55M	$57M	·	$73M	$94M	$67M	·	$58M
Capital Leases	$13M	$14M	$15M	$16M	$15M	$15M	$16M	$17M	$17M	$21M	·	$22M	$23M	$24M	·	$25M
Deferred Tax	$4M	$4M	$6M	$5M	$5M	$5M	$5M	$3M	$3M	$3M	·	$2M	$2M	$2M	·	$2M
Other Non-current Liabilities	$278.0K	$278.0K	$278.0K	$278.0K	$828.0K	$856.0K	$923.0K	$929.0K	$1M	$2M	·	$2M	$4M	$4M	·	$3M
Total Liabilities	$317M	$315M	$78M	$77M	$74M	$101M	$124M	$120M	$109M	$116M	·	$132M	$153M	$127M	·	$121M
Common Stock	$1.13B	$1.13B	$1.11B	$1.09B	$1.07B	$1.02B	$1.02B	$1.01B	$1.01B	$1.00B	·	$932M	$929M	$900M	·	$885M
Retained Earnings	$-1.17B	$-1.07B	$-953M	$-886M	$-851M	$-853M	$-830M	$-798M	$-747M	$-709M	·	$-663M	$-634M	$-583M	·	$-868M
AOCI	$-7M	$-7M	$-6M	$-6M	$-6M	$-6M	$-7M	$-6M	$-8M	$-8M	·	$-8M	$-8M	$-6M	·	$-7M
Stockholders' Equity	$80M	$164M	$269M	$320M	$335M	$325M	$339M	$367M	$406M	$438M	$465M	$424M	$449M	$474M	$493M	$180M
Liabilities + Equity	$397M	$478M	$347M	$397M	$408M	$426M	$463M	$487M	$516M	$554M	·	$556M	$602M	$601M	·	$300M
Shares Outstanding	71,412,072	73,102,689	74,638,413	75,139,281	74,846,147	69,584,811	68,964,319	69,584,882	70,831,545	70,677,106	·	67,922,559	67,687,384	64,083,770	·	61,694,387

Arus Kas 12

Metrik	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Stock-based Comp	$11M	$7M	$9M	$7M	$6M	$6M	$5M	$5M	$5M	$4M	$3M	$2M	$367.0K	$2M	$4M	$5M
Amort. of Intangibles	$176.0K	$176.0K	$185.0K	$648.0K	$2M	$2M	$2M	$980.0K	$812.0K	$702.0K	$673.0K	$672.0K	$678.0K	$679.0K	$529.0K	$166.0K
Operating Cash Flow	$-32M	$-46M	$-10M	$-31M	$12M	$-3M	$-42M	$-6M	$-25M	$-38M	$14M	$-43M	$-6M	$-83M	$327M	$-73M
CapEx	$0	$216.0K	$581.0K	$410.0K	$514.0K	$16.0K	$314.0K	$899.0K	$593.0K	$185.0K	$356.0K	$930.0K	$802.0K	$386.0K	$348.0K	$981.0K
Investing Cash Flow	$17M	$70M	$5M	$368.0K	$9M	$12M	$-6M	$72M	$-20M	$-7M	$-1M	$-7M	$-61M	$-138M	$-22M	$-30M
Stock Issued	·	·	·	·	·	·	$0	$0	·	·	$0	$0	$26M	$0	$0	$0
Stock Repurchased	$52M	$76M	$25M	$16M	$0	$0	$9M	·	·	·	$0	·	·	·	·	·
Net Stock Activity	·	$-76M	·	·	·	·	·	·	·	·	·	·	·	$0	·	·
Financing Cash Flow	$-50M	$179M	$-19M	$-2M	$1M	$1M	$-9M	$-15M	$1M	$2M	$51M	$2M	$28M	$2M	$-377.0K	$628.0K
Net Change in Cash	$-65M	$203M	$-24M	$-33M	$22M	$10M	$-56M	$51M	$-44M	$-43M	$63M	$-48M	$-39M	$-219M	$305M	$-103M
Taxes Paid	$863.0K	$245.0K	$107.0K	$660.0K	$196.0K	$387.0K	$3M	$106.0K	$106.0K	$0	·	·	·	·	·	·
Free Cash Flow	·	$-46M	·	·	·	$-3M	·	·	·	$-38M	·	·	·	$-84M	·	·

Profitabilitas 7

Metrik	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Operating Margin	-919.0%	-1956.7%	·	-80.1%	-1.4%	-94.5%	·	-213.8%	-222.9%	-376.9%	·	-201.4%	-772.8%	-76.7%	·	-1914.0%
Net Margin	-980.8%	-1834.0%	·	-71.0%	4.8%	-83.5%	·	-186.6%	-195.8%	-315.6%	·	-173.8%	-730.5%	-68.5%	·	-1818.6%
Pretax Margin	-986.8%	-1925.0%	·	-66.1%	4.4%	-81.7%	·	-185.2%	-195.5%	-314.8%	·	-167.1%	-706.9%	-64.5%	·	-1819.7%
EBITDA Margin	-919.0%	-1956.7%	·	-80.1%	-1.4%	-94.5%	·	-213.8%	-222.9%	-376.9%	·	-201.4%	-772.8%	-76.7%	·	-1914.0%
ROA	-11.2%	-9.8%	·	-4.4%	0.50%	-4.6%	·	-5.7%	-6.7%	-5.5%	·	-6.7%	-17.0%	-8.1%	·	-31.9%
ROE	-21.7%	-18.1%	·	-5.7%	0.63%	-5.9%	·	-7.5%	-8.8%	-6.9%	·	-9.5%	-22.8%	-10.3%	·	-53.2%
ROIC	-52.2%	-27.4%	·	-7.4%	-0.22%	-8.1%	·	-9.4%	-10.6%	-8.6%	·	-8.2%	-12.5%	-6.1%	·	-28.0%

Likuiditas & Solvabilitas 2

Metrik	Tren	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Current Ratio		6.3	10.8	·	6.9	7.7	4.7	·	4.1	7.0	6.9	·	5.1	4.5	6.3	·	3.3
Quick Ratio		3.9	7.0	·	2.2	2.6	1.5	·	1.7	1.9	2.6	·	5.0	4.2	6.1	·	3.0

Efisiensi 2

Metrik	Tren	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Asset Turnover		0.0	0.0	·	0.1	0.1	0.1	·	0.0	0.0	0.0	·	0.0	0.0	0.1	·	0.0
Receivables Turnover		1.1	0.2	·	1.0	2.8	1.0	·	0.4	0.5	0.2	·	0.4	0.3	1.1	·	0.8

Per Saham 5

Metrik	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Book Value / Share	$1.13	$2.24	·	$4.26	$4.47	$4.67	·	$5.27	$5.73	$6.20	·	$6.25	$6.63	$7.39	·	$2.91
Revenue / Share	$0.06	$0.03	·	$0.36	$0.63	$0.36	·	$0.21	$0.25	$0.13	·	$0.23	$0.10	$0.53	·	$0.04
Cash Flow / Share	·	$-0.61	·	·	·	$-0.05	·	·	·	$-0.49	·	·	·	$-1.25	·	·
Cash / Share	$2.51	$3.34	·	$0.86	$1.31	$1.10	·	$1.76	$1.00	$1.62	·	$1.39	$2.10	$2.83	·	$1.56
EPS (TTM)	$-2.02	$-1.37	·	$-0.85	$-0.98	$-1.50	·	$-1.48	$-1.50	$-1.77	·	$3.24	$2.93	$2.72	·	$-3.83

Valuasi (TTM) 9

Metrik	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Revenue TTM	$37M	$81M	·	$134M	$123M	$93M	·	$62M	$63M	$50M	·	$462M	$448M	$446M	·	$30M
Net Income TTM	$-150M	$-103M	·	$-63M	$-74M	$-114M	·	$-114M	$-113M	$-126M	·	$205M	$186M	$173M	·	$-224M
Market Cap	$1.87B	$1.83B	·	$1.28B	$939M	$829M	·	$873M	$603M	$744M	·	$431M	$585M	$579M	·	$379M
P/E	-12.9	-18.3	·	-20.1	-12.8	-7.9	·	-8.5	-5.7	-5.9	·	2.0	2.9	3.3	·	-1.6
P/S	50.3	22.5	·	9.5	7.6	8.9	·	14.0	9.6	14.7	·	0.9	1.3	1.3	·	12.7
P/B	23.2	11.2	·	4.0	2.8	2.6	·	2.4	1.5	1.7	·	1.0	1.3	1.2	·	2.1
P / Tangible Book	27.7	12.2	·	4.2	2.9	2.7	·	2.5	1.6	1.8	·	1.1	1.4	1.3	·	2.4
P / Cash Flow	·	-40.0	·	·	·	-243.3	·	·	·	-19.7	·	·	·	-7.0	·	·
Earnings Yield	-7.7%	-5.5%	·	-5.0%	-7.8%	-12.6%	·	-11.8%	-17.6%	-16.8%	·	51.1%	33.9%	30.1%	·	-62.3%

Periode terbaru di sebelah kiri · nilai null ditampilkan sebagai ·

Laporan Keuangan Laporan laba rugi, neraca, arus kas — tahunan, 5 tahun terakhir

16

Metrik	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Pendapatan	$106M	$76M	$76M	$412M	$27M
Margin Operasi %	-87.3%	-179.7%	-181.6%	·	·
Laba Bersih	$-81M	$-123M	$-119M	$124M	$-212M
EPS Dilusian	$-1.08	$-1.62	$-1.72	$1.90	$-4.61

Metrik	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Rasio Lancar	5.9	3.4	7.4	·	·
Rasio Cepat	1.1	1.4	7.1	·	·

Metrik	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Arus Kas Bebas	$-35M	$-112M	$-121M	·	·

Pemilik institusional (13F) 212 pengaju · $1.9B total · Per tanggal 30 Sep. 2026

17

Institusi yang melaporkan kepemilikan saham ini dalam SEC Form 13F triwulanan mereka. Hanya posisi panjang; satu pengaju dapat muncul dua kali untuk leg opsi terpisah. Kaki put/call offset yang besar biasanya mencerminkan pembuatan pasar atau inventaris yang dilindungi, bukan keyakinan arah.

Pemegang 212

Nilai yang dipegang $1.9B

Posisi baru 22

Posisi yang keluar 31

Aktivitas institusional — Q2 2026 vs kuartal sebelumnya

Posisi baru	Posisi yang keluar	Meningkat	Menurun	Perubahan bersih saham
22 (-20 vs Kuartal sebelumnya)	31 (0 vs Kuartal sebelumnya)	59 (-16 vs Kuartal sebelumnya)	73 (+13 vs Kuartal sebelumnya)	-2.0M

Dibandingkan dengan Q1 2026. Pengajuan Formulir 13F SEC jatuh tempo dalam waktu 45 hari setelah akhir kuartal ditambah kelonggaran singkat untuk pengaju terlambat — kuartal yang masih dalam jangka waktu tersebut dilewati demi pasangan terakhir yang dilaporkan sepenuhnya.

Institusi	Nilai	Saham	% dari 13F yang dilacak	Tipe
EcoR1 Capital, LLC	$600.445.942	22.970.388	32,29%	Saham
Rubric Capital Management LP	$182.980.000	7.000.000	9,84%	Saham
BlackRock, Inc.	$111.121.925	4.251.030	5,98%	Saham
PERCEPTIVE ADVISORS LLC	$109.342.391	4.182.953	5,88%	Saham
BVF INC/IL	$95.388.572	3.649.142	5,13%	Saham
VANGUARD GROUP INC	$61.315.382	2.328.727	3,30%	Saham
MORGAN STANLEY	$58.325.141	2.231.260	3,14%	Saham
BNP PARIBAS ASSET MANAGEMENT Holding S.A.	$46.558.373	1.781.116	2,50%	Saham
VANGUARD CAPITAL MANAGEMENT LLC	$40.752.208	1.558.998	2,19%	Saham
Assenagon Asset Management S.A.	$32.727.986	1.252.027	1,76%	Saham
Nextech Invest Ltd.	$29.118.548	1.113.946	1,57%	Saham
STATE STREET CORP	$28.445.966	1.088.216	1,53%	Saham
DIMENSIONAL FUND ADVISORS LP	$25.995.770	994.955	1,40%	Saham
CITADEL ADVISORS LLC	$23.895.516	914.136	1,29%	Saham
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	$23.259.000	889.802	1,25%	Saham
FMR LLC	$18.365.133	702.568	0,99%	Saham
GEODE CAPITAL MANAGEMENT, LLC	$18.099.012	692.410	0,97%	Saham
Prosight Management, LP	$17.629.705	674.434	0,95%	Saham
Qube Research & Technologies Ltd	$15.516.443	593.590	0,83%	Saham
VANGUARD PORTFOLIO MANAGEMENT LLC	$13.332.236	510.032	0,72%	Saham
Redmile Group, LLC	$12.851.836	491.654	0,69%	Saham
Capricorn Fund Managers Ltd	$12.717.868	486.529	0,68%	Saham
GOLDMAN SACHS GROUP INC	$12.307.288	470.822	0,66%	Saham
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	$10.939.512	418.497	0,59%	Saham
DEUTSCHE BANK AG\	$10.382.547	397.190	0,56%	Saham
Hillsdale Investment Management Inc.	$10.009.581	382.922	0,54%	Saham
FIRST TRUST ADVISORS LP	$8.897.088	340.363	0,48%	Saham
Granahan Investment Management, LLC	$8.787.144	336.157	0,47%	Saham
NORTHERN TRUST CORP	$8.392.849	321.073	0,45%	Saham
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	$7.997.401	319.385	0,43%	Saham
Pictet Asset Management Holding SA	$7.446.189	308.187	0,40%	Saham
PICTON MAHONEY ASSET MANAGEMENT	$7.092.908	271.343	0,38%	Saham
SILVERCREST ASSET MANAGEMENT GROUP LLC	$5.849.243	223.766	0,31%	Saham
BANK OF AMERICA CORP /DE/	$5.726.515	219.071	0,31%	Saham
WELLS FARGO & COMPANY/MN	$5.677.573	217.199	0,31%	Saham
SummitTX Capital, L.P.	$5.510.364	210.802	0,30%	Saham
Man Group plc	$5.509.763	210.779	0,30%	Saham
FEDERATED HERMES, INC.	$4.914.190	187.995	0,26%	Saham
RAYMOND JAMES FINANCIAL INC	$4.350.114	166.416	0,23%	Saham
STATE OF WISCONSIN INVESTMENT BOARD	$4.066.835	155.579	0,22%	Saham
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	$3.984.154	152.416	0,21%	Saham
KENNEDY CAPITAL MANAGEMENT LLC	$3.800.390	145.386	0,20%	Saham
D. E. Shaw & Co., Inc.	$3.785.255	144.807	0,20%	Saham
DIADEMA PARTNERS LP	$3.715.330	142.132	0,20%	Saham
CITIGROUP INC	$3.435.868	131.441	0,18%	Saham
Bank of New York Mellon Corp	$3.427.107	131.106	0,18%	Saham
SUSQUEHANNA INTERNATIONAL GROUP, LLP	$3.408.656	130.400	0,18%	Opsi beli
XTX Topco Ltd	$3.290.425	125.877	0,18%	Saham
Nuveen, LLC	$3.120.829	119.389	0,17%	Saham
PANAGORA ASSET MANAGEMENT INC	$3.100.282	118.603	0,17%	Saham

Tampilkan semua 212 pemilik institusional →

Aktivis & pemilik 5%+ 2 saham

18

Investor yang mengajukan Jadwal 13D SEC — kepemilikan manfaat di atas 5% dengan niat untuk memengaruhi penerbit (kepemilikan aktivis, kampanye dewan, M&A). Setiap baris menunjukkan status terbaru yang diketahui dari posisi pengaju tersebut.

Pengaju	Diajukan	Kepemilikan	Status	Tujuan	Pengajuan
EcoR1 Capital, LLC, Oleg Nodelman, EcoR1 Capital Fund Qualified, L.P. ×8 pengajuan	19 Nov. 2025	30,70%	Amandemen	Kampanye dewan	SEC
All Blue Falcons FZE, Daniel Edward Llewellen Cookson ×2 pengajuan	28 Des. 2022	·	Pengajuan awal	·	SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Orang dalam perusahaan 28 orang dalam · 12 pejabat · 17 direktur

19

Orang Dalam	Peran	Aktivitas terakhir	Saham dimiliki	Jual 12m	Bersih 12m
Kenneth Galbraith	Chair & CEO	12 Jan. 2026 A	226.842	4	$-3.337.929
Kristin Stafford	EVP, Chief Financial Officer	6 April 2026 A	·	0	$0
Christopher Astle	SVP & Chief Financial Officer	5 Jan. 2024 A	6.503	0	$0
Neil A Klompas	President & COO	10 Maret 2023 M	17.032	0	$0
Mark Hollywood	EVP & Chief Operating Officer	6 Juli 2026 A	133.852	1	$-138.740
Paul R Schneider	EVP, General Counsel	13 Mei 2026 A	·	0	$0
Adam Schayowitz	EVP, Head of Research & Development	9 April 2026 A	·	0	$0
Scott Platshon	EVP, Chief Business Officer	9 April 2026 A	·	0	$0
Paul Andrew Moore	Chief Scientific Officer	12 Jan. 2026 A	48.497	3	$-721.486
Jeffrey T L Smith	EVP & Chief Medical Officer	12 Jan. 2026 M	26.708	2	$-475.562
Leone D Patterson	EVP, Chief Bus & Fin Officer	6 Jan. 2026 A	459	0	$0
Neil Josephson	Chief Medical Officer	10 Nov. 2022 M	14.449	0	$0
Gregory A. Ciongoli	Direktur	12 Jan. 2026 A	488.500	0	$0
Alessandra Cesano	Direktur	12 Jan. 2026 A	·	0	$0
Carlos Campoy	Direktur	12 Jan. 2026 A	·	0	$0
Robert E Landry	Direktur	12 Jan. 2026 A	·	0	$0
Kelvin Neu	Direktur	12 Jan. 2026 A	·	0	$0
Susan Mahony	Direktur	12 Jan. 2026 A	·	0	$0
Brian N Cherry	Direktur	12 Jan. 2026 A	·	0	$0
EcoR1 Capital, LLC	Direktur	17 Jan. 2025 P	15.720.161	0	$0
Nancy Davidson	Direktur	10 Des. 2024 A	·	0	$0
Neil Gallagher	Direktur	10 Des. 2024 A	·	0	$0
Derek John Michael Miller	Direktur	10 Des. 2024 A	·	0	$0
Troy Cox	Direktur	10 Des. 2024 A	·	0	$0
Kenneth J. Hillan	Direktur	7 Des. 2023 A	·	0	$0
Hollings Renton	Direktur	7 Des. 2023 A	·	0	$0
Natalie Sacks	Direktur	21 Des. 2022 A	·	0	$0
Lota S. Zoth	Direktur	21 Des. 2022 A	·	0	$0

Orang dalam dari pengajuan SEC Form 3/4/5; bersih = hanya P/S pasar terbuka

Kepemilikan ETF Dimiliki oleh 31 ETF

20

Bobot mencerminkan kepemilikan ekuitas langsung (N-PORT) saja; dana berbasis leverage atau derivatif mungkin memiliki eksposur swap tambahan yang tidak ditampilkan.

Dana	Bobot	Unit	Per tanggal	Sumber
BBP · ETFis Series Trust I	1,32%	59.315 NS	31 Juli 2026	N-PORT
DWAS · Invesco Exchange-Traded Fund Trust …	0,38%	59.314 SH	2 Okt. 2026	Harian
OMFS · Invesco Exchange-Traded Self-Indexe…	0,14%	14.705 SH	2 Okt. 2026	Harian
IBB · iShares Trust	0,14%	537.742 SH	11 Sep. 2026	Harian
IBBQ · Invesco Exchange-Traded Fund Trust …	0,12%	5.008 SH	2 Okt. 2026	Harian
FYC · First Trust Exchange-Traded AlphaDE…	0,11%	65.877 NS	31 Juli 2026	N-PORT
VFMO · VANGUARD WELLINGTON FUND	0,10%	74.514 SH	19 Agu 2026	Harian
IWO · iShares Trust	0,08%	439.290 SH	11 Sep. 2026	Harian
VTWG · VANGUARD SCOTTSDALE FUNDS	0,07%	50.443 SH	19 Agu 2026	Harian
PRFZ · Invesco Exchange-Traded Fund Trust	0,07%	66.685 SH	2 Okt. 2026	Harian
IWM · iShares Trust	0,04%	1.202.863 SH	11 Sep. 2026	Harian
VTWO · VANGUARD SCOTTSDALE FUNDS	0,04%	270.692 SH	19 Agu 2026	Harian
RSSL · Global X Funds	0,03%	22.528 NS	31 Juli 2026	N-PORT
DFAS · Dimensional ETF Trust	0,03%	189.632 NS	31 Juli 2026	N-PORT
FAD · First Trust Exchange-Traded AlphaDE…	0,02%	5.969 NS	31 Juli 2026	N-PORT
ISCG · iShares Trust	0,02%	5.910 SH	11 Sep. 2026	Harian
FHLC · FIDELITY COVINGTON TRUST	0,01%	18.267 NS	31 Juli 2026	N-PORT
WSML · iShares Trust	0,01%	3.039 SH	11 Sep. 2026	Harian
VHT · VANGUARD WORLD FUND	0,01%	110.298 SH	19 Agu 2026	Harian
TILT · FlexShares Trust	0,01%	5.508 NS	31 Juli 2026	N-PORT
DFAC · Dimensional ETF Trust	0,00%	70.572 NS	31 Juli 2026	N-PORT
DCOR · Dimensional ETF Trust	0,00%	3.968 NS	31 Juli 2026	N-PORT
DFAU · Dimensional ETF Trust	0,00%	12.951 NS	31 Juli 2026	N-PORT
IWV · iShares Trust	0,00%	14.406 SH	10 Sep. 2026	Harian
DFUS · Dimensional ETF Trust	0,00%	8.364 NS	31 Juli 2026	N-PORT
DXUV · Dimensional ETF Trust	0,00%	130 NS	31 Juli 2026	N-PORT
VTI · VANGUARD INDEX FUNDS	0,00%	1.508.613 SH	19 Agu 2026	Harian
VTHR · VANGUARD SCOTTSDALE FUNDS	0,00%	4.085 SH	19 Agu 2026	Harian
ISCB · iShares Trust	·	1.999 SH	11 Sep. 2026	Harian
ISCV · iShares Trust	·	5.753 SH	11 Sep. 2026	Harian
SMMV · iShares Trust	·	16.029 SH	19 Agu 2026	Harian

ZYME Konsensus Analis Opini analis bullish dan bearish, target harga 12 bulan, potensi kenaikan

21

peringkat · 18 analis BELI

Target median $38.00 +51,1%

6 33,3% Beli Kuat

11 61,1% Beli

1 5,6% Tahan

0 0,0% Jual

0 0,0% Jual Kuat

Target Harga 12 Bulan

14 analis · 2026-10-04

Target rata-rata $41.07 +63,3%

← Di bawah semua target Harga saat ini $25.15

Rendah$32.00 Rata-rata$41.07 Tinggi$60.00

Perbandingan rekan (sub-industri GICS) Metrik utama vs rekan sektor

22

Dasar FY, harga per penutupan akhir tahun fiskal terakhir setiap perusahaan.

Ticker	Kapitalisasi Pasar	P/E	Pendapatan YoY	Margin Bersih	ROE	Margin Kotor
ZYME	$1.97B	-24.4	38.9%	-76.6%	-26.9%	·
AUPH	$2.11B	7.7	20.4%	101.5%	62.7%	·
ABUS	$926M	-28.3	128.2%	-237.9%	-42.0%	·
ACOG	$141M	-5.5	·	-202.2%	-43.8%	·
ENGN	·	·	·	·	·	·
XENE	$3.59B	-10.3	·	-4612.1%	-56.9%	·

Metrik Saya Daftar pantauan pribadi Anda — baris yang dipilih dari Fundamental Lengkap

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ZYME Zymeworks Inc. - Common Stock