ZYME — Pemilik institusional (13F)
Institusi yang melaporkan kepemilikan saham ini dalam SEC Form 13F triwulanan mereka. Hanya posisi panjang; satu pengaju dapat muncul dua kali untuk leg opsi terpisah. Kaki put/call offset yang besar biasanya mencerminkan pembuatan pasar atau inventaris yang dilindungi, bukan keyakinan arah.
| Institusi | Nilai | Saham | % dari 13F yang dilacak | Tipe |
|---|---|---|---|---|
| EcoR1 Capital, LLC | $600.445.942 | 22.970.388 | 32,29% | Saham |
| Rubric Capital Management LP | $182.980.000 | 7.000.000 | 9,84% | Saham |
| BlackRock, Inc. | $111.121.925 | 4.251.030 | 5,98% | Saham |
| PERCEPTIVE ADVISORS LLC | $109.342.391 | 4.182.953 | 5,88% | Saham |
| BVF INC/IL | $95.388.572 | 3.649.142 | 5,13% | Saham |
| VANGUARD GROUP INC | $61.315.382 | 2.328.727 | 3,30% | Saham |
| MORGAN STANLEY | $58.325.141 | 2.231.260 | 3,14% | Saham |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $46.558.373 | 1.781.116 | 2,50% | Saham |
| VANGUARD CAPITAL MANAGEMENT LLC | $40.752.208 | 1.558.998 | 2,19% | Saham |
| Assenagon Asset Management S.A. | $32.727.986 | 1.252.027 | 1,76% | Saham |
| Nextech Invest Ltd. | $29.118.548 | 1.113.946 | 1,57% | Saham |
| STATE STREET CORP | $28.445.966 | 1.088.216 | 1,53% | Saham |
| DIMENSIONAL FUND ADVISORS LP | $25.995.770 | 994.955 | 1,40% | Saham |
| CITADEL ADVISORS LLC | $23.895.516 | 914.136 | 1,29% | Saham |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $23.259.000 | 889.802 | 1,25% | Saham |
| FMR LLC | $18.365.133 | 702.568 | 0,99% | Saham |
| GEODE CAPITAL MANAGEMENT, LLC | $18.099.012 | 692.410 | 0,97% | Saham |
| Prosight Management, LP | $17.629.705 | 674.434 | 0,95% | Saham |
| Qube Research & Technologies Ltd | $15.516.443 | 593.590 | 0,83% | Saham |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $13.332.236 | 510.032 | 0,72% | Saham |
| Redmile Group, LLC | $12.851.836 | 491.654 | 0,69% | Saham |
| Capricorn Fund Managers Ltd | $12.717.868 | 486.529 | 0,68% | Saham |
| GOLDMAN SACHS GROUP INC | $12.307.288 | 470.822 | 0,66% | Saham |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $10.939.512 | 418.497 | 0,59% | Saham |
| DEUTSCHE BANK AG\ | $10.382.547 | 397.190 | 0,56% | Saham |
| Hillsdale Investment Management Inc. | $10.009.581 | 382.922 | 0,54% | Saham |
| FIRST TRUST ADVISORS LP | $8.897.088 | 340.363 | 0,48% | Saham |
| Granahan Investment Management, LLC | $8.787.144 | 336.157 | 0,47% | Saham |
| NORTHERN TRUST CORP | $8.392.849 | 321.073 | 0,45% | Saham |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $7.997.401 | 319.385 | 0,43% | Saham |
| Pictet Asset Management Holding SA | $7.446.189 | 308.187 | 0,40% | Saham |
| PICTON MAHONEY ASSET MANAGEMENT | $7.092.908 | 271.343 | 0,38% | Saham |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $5.849.243 | 223.766 | 0,31% | Saham |
| BANK OF AMERICA CORP /DE/ | $5.726.515 | 219.071 | 0,31% | Saham |
| WELLS FARGO & COMPANY/MN | $5.677.573 | 217.199 | 0,31% | Saham |
| SummitTX Capital, L.P. | $5.510.364 | 210.802 | 0,30% | Saham |
| Man Group plc | $5.509.763 | 210.779 | 0,30% | Saham |
| FEDERATED HERMES, INC. | $4.914.190 | 187.995 | 0,26% | Saham |
| RAYMOND JAMES FINANCIAL INC | $4.350.114 | 166.416 | 0,23% | Saham |
| STATE OF WISCONSIN INVESTMENT BOARD | $4.066.835 | 155.579 | 0,22% | Saham |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3.984.154 | 152.416 | 0,21% | Saham |
| KENNEDY CAPITAL MANAGEMENT LLC | $3.800.390 | 145.386 | 0,20% | Saham |
| D. E. Shaw & Co., Inc. | $3.785.255 | 144.807 | 0,20% | Saham |
| DIADEMA PARTNERS LP | $3.715.330 | 142.132 | 0,20% | Saham |
| CITIGROUP INC | $3.435.868 | 131.441 | 0,18% | Saham |
| Bank of New York Mellon Corp | $3.427.107 | 131.106 | 0,18% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3.408.656 | 130.400 | 0,18% | Opsi beli |
| XTX Topco Ltd | $3.290.425 | 125.877 | 0,18% | Saham |
| Nuveen, LLC | $3.120.829 | 119.389 | 0,17% | Saham |
| PANAGORA ASSET MANAGEMENT INC | $3.100.282 | 118.603 | 0,17% | Saham |
| UBS Group AG | $3.008.583 | 115.095 | 0,16% | Saham |
| Invesco Ltd. | $2.933.222 | 112.212 | 0,16% | Saham |
| AQR CAPITAL MANAGEMENT LLC | $2.908.911 | 111.282 | 0,16% | Saham |
| WELLINGTON MANAGEMENT GROUP LLP | $2.875.766 | 110.014 | 0,15% | Saham |
| PLATINUM INVESTMENT MANAGEMENT LTD | $2.749.510 | 105.184 | 0,15% | Saham |
| AXA Investment Managers S.A. | $2.705.745 | 158.416 | 0,15% | Saham |
| Manatuck Hill Partners, LLC | $2.614.000 | 100.000 | 0,14% | Saham |
| JPMORGAN CHASE & CO | $2.564.192 | 106.398 | 0,14% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2.451.932 | 93.800 | 0,13% | Opsi jual |
| KORNITZER CAPITAL MANAGEMENT INC /KS | $2.321.232 | 88.800 | 0,12% | Saham |
| MACKENZIE FINANCIAL CORP | $2.293.654 | 87.745 | 0,12% | Saham |
| PRINCIPAL FINANCIAL GROUP INC | $2.221.639 | 84.990 | 0,12% | Saham |
| Y-Intercept (Hong Kong) Ltd | $2.181.514 | 83.455 | 0,12% | Saham |
| LMR Partners LLP | $2.156.550 | 82.500 | 0,12% | Saham |
| AMERIPRISE FINANCIAL INC | $2.150.380 | 82.264 | 0,12% | Saham |
| VANGUARD FIDUCIARY TRUST CO | $2.094.337 | 80.120 | 0,11% | Saham |
| STIFEL FINANCIAL CORP | $2.018.373 | 77.214 | 0,11% | Saham |
| FRANKLIN RESOURCES INC | $2.000.443 | 76.528 | 0,11% | Saham |
| TEMA ETFS LLC | $2.000.422 | 75.975 | 0,11% | Saham |
| RHUMBLINE ADVISERS | $1.962.211 | 75.066 | 0,11% | Saham |
| Swiss National Bank | $1.939.588 | 74.200 | 0,10% | Saham |
| MARTINGALE ASSET MANAGEMENT L P | $1.915.592 | 73.282 | 0,10% | Saham |
| TWO SIGMA INVESTMENTS, LP | $1.878.786 | 71.874 | 0,10% | Saham |
| Dana Investment Advisors, Inc. | $1.873.192 | 71.660 | 0,10% | Saham |
| CREDIT AGRICOLE S A | $1.855.940 | 71.000 | 0,10% | Saham |
| Fisher Asset Management, LLC | $1.850.057 | 70.775 | 0,10% | Saham |
| SEGALL BRYANT & HAMILL, LLC | $1.747.093 | 66.836 | 0,09% | Saham |
| Verdad Advisers, LP | $1.743.224 | 66.688 | 0,09% | Saham |
| Susquehanna Portfolio Strategies, LLC | $1.705.583 | 65.248 | 0,09% | Saham |
| Campbell & CO Investment Adviser LLC | $1.591.246 | 60.874 | 0,09% | Saham |
| ROYAL BANK OF CANADA | $1.471.000 | 56.278 | 0,08% | Saham |
| ALLIANCEBERNSTEIN L.P. | $1.399.636 | 55.896 | 0,08% | Saham |
| CITADEL ADVISORS LLC | $1.364.508 | 52.200 | 0,07% | Opsi beli |
| Virtus Investment Advisers, LLC | $1.328.566 | 50.825 | 0,07% | Saham |
| ENVESTNET ASSET MANAGEMENT INC | $1.272.365 | 48.675 | 0,07% | Saham |
| Russell Investments Group, Ltd. | $1.251.241 | 47.867 | 0,07% | Saham |
| Quantinno Capital Management LP | $1.245.362 | 47.642 | 0,07% | Saham |
| Legal & General Group Plc | $1.128.017 | 43.160 | 0,06% | Saham |
| VICTORY CAPITAL MANAGEMENT INC | $1.111.577 | 42.524 | 0,06% | Saham |
| MARSHALL WACE, LLP | $1.070.380 | 40.948 | 0,06% | Saham |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | $1.033.419 | 39.534 | 0,06% | Saham |
| Aquilo Capital Management, LLC | $1.006.181 | 84.482 | 0,05% | Saham |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $986.628 | 37.744 | 0,05% | Saham |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $965.141 | 36.922 | 0,05% | Saham |
| TUDOR INVESTMENT CORP ET AL | $953.352 | 36.471 | 0,05% | Saham |
| HighTower Advisors, LLC | $943.654 | 36.100 | 0,05% | Saham |
| Persistent Asset Partners Ltd | $939.341 | 35.935 | 0,05% | Saham |
| HighVista Strategies LLC | $889.100 | 34.013 | 0,05% | Saham |
| COMMONWEALTH EQUITY SERVICES, LLC | $837.838 | 32.052 | 0,05% | Saham |
| TWO SIGMA ADVISERS, LP | $827.157 | 31.415 | 0,04% | Saham |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $807.360 | 30.886 | 0,04% | Saham |
| Creative Planning | $777.168 | 29.731 | 0,04% | Saham |
| SBI Okasan Asset Management Co.Ltd. | $771.200 | 32.000 | 0,04% | Saham |
| MetLife Investment Management, LLC | $728.888 | 27.884 | 0,04% | Saham |
| JOURNEY STRATEGIC WEALTH LLC | $727.412 | 29.050 | 0,04% | Saham |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $723.294 | 27.670 | 0,04% | Saham |
| STRS OHIO | $692.710 | 26.500 | 0,04% | Saham |
| VANGUARD ASSET MANAGEMENT, Ltd | $686.933 | 26.279 | 0,04% | Saham |
| Brevan Howard Capital Management LP | $678.490 | 25.956 | 0,04% | Saham |
| Jump Financial, LLC | $669.393 | 25.608 | 0,04% | Saham |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $657.735 | 25.162 | 0,04% | Saham |
| RITHOLTZ WEALTH MANAGEMENT | $633.712 | 24.243 | 0,03% | Saham |
| BNP PARIBAS FINANCIAL MARKETS | $607.206 | 23.229 | 0,03% | Saham |
| Duncan Williams Asset Management, LLC | $577.563 | 22.095 | 0,03% | Saham |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $564.049 | 21.578 | 0,03% | Saham |
| BARCLAYS PLC | $538.562 | 20.603 | 0,03% | Saham |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $508.031 | 19.435 | 0,03% | Saham |
| SIMPLEX TRADING, LLC | $507.926 | 19.431 | 0,03% | Saham |
| BetterWealth, LLC | $486.779 | 18.622 | 0,03% | Saham |
| BANK OF MONTREAL /CAN/ | $481.394 | 18.416 | 0,03% | Saham |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $477.499 | 18.267 | 0,03% | Saham |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | $475.356 | 18.185 | 0,03% | Saham |
| JANUS HENDERSON GROUP PLC | $455.819 | 18.200 | 0,02% | Saham |
| JANE STREET GROUP, LLC | $455.803 | 17.437 | 0,02% | Saham |
| NEW YORK STATE COMMON RETIREMENT FUND | $454.078 | 17.371 | 0,02% | Saham |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $452.483 | 17.310 | 0,02% | Saham |
| Squarepoint Ops LLC | $423.468 | 16.200 | 0,02% | Saham |
| HSBC HOLDINGS PLC | $421.205 | 15.588 | 0,02% | Saham |
| Vinva Investment Management Ltd | $419.717 | 11.983 | 0,02% | Saham |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $400.988 | 15.340 | 0,02% | Saham |
| AGF MANAGEMENT LTD | $392.100 | 15.000 | 0,02% | Saham |
| Police & Firemen's Retirement System of New Jersey | $358.170 | 13.702 | 0,02% | Saham |
| INTECH INVESTMENT MANAGEMENT LLC | $311.981 | 11.935 | 0,02% | Saham |
| State of New Jersey Common Pension Fund D | $311.667 | 11.923 | 0,02% | Saham |
| China Universal Asset Management Co., Ltd. | $303.799 | 11.622 | 0,02% | Saham |
| JAMES INVESTMENT RESEARCH, INC. | $285.580 | 10.925 | 0,02% | Saham |
| Ewing Morris & Co. Investment Partners Ltd. | $283.619 | 10.850 | 0,02% | Saham |
| ARIZONA STATE RETIREMENT SYSTEM | $265.975 | 10.175 | 0,01% | Saham |
| Jain Global LLC | $261.661 | 10.010 | 0,01% | Saham |
| PSP Research LLC | $261.400 | 10.000 | 0,01% | Saham |
| Mitsubishi UFJ Trust & Banking Corp | $250.134 | 9.569 | 0,01% | Saham |
| VOYA INVESTMENT MANAGEMENT LLC | $243.991 | 9.334 | 0,01% | Saham |
| Vanguard Investments Australia, Ltd. | $230.110 | 8.803 | 0,01% | Saham |
| Allspring Global Investments Holdings, LLC | $225.359 | 8.762 | 0,01% | Saham |
| ProShare Advisors LLC | $223.681 | 8.557 | 0,01% | Saham |
| AlphaQuest LLC | $218.881 | 8.313 | 0,01% | Saham |
| INCEPTIONR LLC | $217.302 | 8.313 | 0,01% | Saham |
| Magnetar Financial LLC | $216.753 | 8.292 | 0,01% | Saham |
| KLP KAPITALFORVALTNING AS | $209.120 | 8.000 | 0,01% | Saham |
| PRUDENTIAL FINANCIAL INC | $207.552 | 7.940 | 0,01% | Saham |
| CWM, LLC | $174.153 | 6.955 | 0,01% | Saham |
| Vanguard Global Advisers, LLC | $142.698 | 5.459 | 0,01% | Saham |
| Northwest & Ethical Investments L.P. | $111.583 | 4.630 | 0,01% | Saham |
| Ameritas Investment Partners, Inc. | $108.847 | 4.164 | 0,01% | Saham |
| Mirae Asset Global Investments Co., Ltd. | $85.373 | 3.266 | 0,00% | Saham |
| Arax Advisory Partners | $78.368 | 2.998 | 0,00% | Saham |
| State of Wyoming | $72.983 | 2.792 | 0,00% | Saham |
| Tower Research Capital LLC (TRC) | $62.030 | 2.373 | 0,00% | Saham |
| GF FUND MANAGEMENT CO. LTD. | $41.432 | 1.585 | 0,00% | Saham |
| TD Waterhouse Canada Inc. | $37.014 | 1.439 | 0,00% | Saham |
| Caitong International Asset Management Co., Ltd | $34.217 | 1.309 | 0,00% | Saham |
| Eurizon Capital SGR S.p.A. | $31.865 | 1.321 | 0,00% | Saham |
| GAMMA Investing LLC | $29.120 | 1.114 | 0,00% | Saham |
| Optiver Holding B.V. | $27.159 | 1.039 | 0,00% | Saham |
| Steward Partners Investment Advisory, LLC | $25.382 | 971 | 0,00% | Saham |
| LANARK FINANCIAL, INC. | $25.146 | 962 | 0,00% | Saham |
| PNC Financial Services Group, Inc. | $23.474 | 898 | 0,00% | Saham |
| OSAIC HOLDINGS, INC. | $23.055 | 882 | 0,00% | Saham |
| JONES FINANCIAL COMPANIES LLLP | $20.214 | 837 | 0,00% | Saham |
| Freestone Grove Partners LP | $16.939 | 648 | 0,00% | Saham |
| NATIONAL BANK OF CANADA /FI/ | $15.182 | 581 | 0,00% | Saham |
| Federation des caisses Desjardins du Quebec | $14.894 | 570 | 0,00% | Saham |
| NISA INVESTMENT ADVISORS, LLC | $12.573 | 481 | 0,00% | Saham |
| UMB Bank, n.a. | $12.129 | 464 | 0,00% | Saham |
| HUNTINGTON NATIONAL BANK | $12.024 | 460 | 0,00% | Saham |
| Parallel Advisors, LLC | $8.600 | 329 | 0,00% | Saham |
| US BANCORP \DE\ | $8.234 | 315 | 0,00% | Saham |
| SBI Securities Co., Ltd. | $8.156 | 312 | 0,00% | Saham |
| COMERICA BANK | $5.556 | 211 | 0,00% | Saham |
| Quarry LP | $5.489 | 210 | 0,00% | Saham |
| EverSource Wealth Advisors, LLC | $4.888 | 187 | 0,00% | Saham |
| Lindbrook Capital, LLC | $4.419 | 371 | 0,00% | Saham |
| Sterling Capital Management LLC | $4.313 | 165 | 0,00% | Saham |
| Fortitude Family Office, LLC | $3.032 | 116 | 0,00% | Saham |
| Allworth Financial LP | $2.824 | 108 | 0,00% | Saham |
| IFP Advisors, Inc | $2.509 | 96 | 0,00% | Saham |
| Versant Capital Management, Inc | $2.490 | 94 | 0,00% | Saham |
| ROTHSCHILD INVESTMENT LLC | $2.091 | 80 | 0,00% | Saham |
| HighMark Wealth Management LLC | $2.091 | 80 | 0,00% | Saham |
| SJS Investment Consulting Inc. | $2.013 | 77 | 0,00% | Saham |
| Kilter Group LLC | $1.726 | 66 | 0,00% | Saham |
| Bare Financial Services, Inc | $1.673 | 64 | 0,00% | Saham |
| Rockefeller Capital Management L.P. | $1.595 | 61 | 0,00% | Saham |
| True Wealth Design, LLC | $1.517 | 58 | 0,00% | Saham |
| Physician Wealth Advisors, Inc. | $1.334 | 51 | 0,00% | Saham |
| North Growth Management Ltd. | $1.201 | 46.000 | 0,00% | Saham |
| PRICE T ROWE ASSOCIATES INC /MD/ | $1.007 | 38.486 | 0,00% | Saham |
| Farther Finance Advisors, LLC | $784 | 30 | 0,00% | Saham |
| Sunbelt Securities, Inc. | $676 | 27 | 0,00% | Saham |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | $643 | 25 | 0,00% | Saham |
| Jackson Creek Investment Advisors LLC | $409 | 18.648 | 0,00% | Saham |
| Essential Partners LLC | $314 | 12 | 0,00% | Saham |
| Janney Montgomery Scott LLC | $310 | 11.865 | 0,00% | Saham |
| Smartleaf Asset Management LLC | $289 | 12 | 0,00% | Saham |
| SG Americas Securities, LLC | $165 | 6.321 | 0,00% | Saham |
| Clearstead Advisors, LLC | $157 | 6 | 0,00% | Saham |
| Larson Financial Group LLC | $157 | 6 | 0,00% | Saham |
| Silver Grove Financial Group, Inc. | $105 | 4 | 0,00% | Saham |
| DekaBank Deutsche Girozentrale | $94 | 3.843 | 0,00% | Saham |
| Hughes Financial Services, LLC | $78 | 3 | 0,00% | Saham |
| SHELL ASSET MANAGEMENT CO | $72 | 4.212 | 0,00% | Saham |
| Covestor Ltd | $1 | 40 | 0,00% | Saham |