ACAD ACADIA Pharmaceuticals Inc. - Common Stock

NASDAQ · Biotechnology · Visualizza su SEC EDGAR ↗
$30,66
Prezzo · Ago 19, 2026
Fondamentali al Ago 5, 2026

Informazioni su ACADIA Pharmaceuticals Inc. - Common Stock Panoramica della società da Wikipedia

Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, California.

Leggi di più

Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, California.

Product development

Nuplazid, a drug developed by Acadia in the late 1990s, "was designed to stimulate a subset of the brain’s serotonin receptors, or the proteins that govern memory, cognition and learning." On April 29, 2016, the FDA approved Acadia's drug, Nuplazid, for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis. Nuplazid is the trade name for Acadia's proprietary molecule, pimavanserin, a selective serotonin inverse agonist preferentially targeting 5-HT2a receptors. Acadia had partnered with Biovail in the late-stage clinical testing of the drug, which showed trial failures as of 2009.

Acadia is running multiple Phase 2 and Phase 3 trials with pimavanserin in several central nervous system conditions: dementia-related psychosis, major depressive disorder, schizophrenia inadequate response, and schizophrenia negative symptoms.

As of 1997, Acadia was among several companies that licensed compounds from Genzyme's small-molecule compound library.

In 2023, the FDA approved trofinetide (marketed as Daybue) for use in Rett syndrome.

History

Acadia started in 1993 as Receptor Technologies, based in Winooski, Vermont. In 1997, the company relocated all operations and management from Vermont to San Diego, California, as a strategic move to garner partnerships with other biotechnology companies. However, the company also had an office in Denmark, in which it received a crucial part of its early investments from BankInvest, under managing director Florian Schönharting, Kommunernes Pensionsforsikring A/S and Dansk Kapitalanlæg Aktieselskab as well as private investor Lars Christiansen. At the time, the company had fifty employees, fourteen of whom were in the Denmark office. The focus of the company in its early years was on genetic screens for receptors, aiming to accelerate early stage drug discovery.

The company planned to conduct an initial public offering (IPO) consisting of 31.6% of the company in 2001, with the intention of raising US$64 million and listing on the NASDAQ exchange under the symbol ACAD. At the time, Acadia and Allergan were collaborating on development of a treatment for glaucoma, and Allergan would retain a 6.3% ownership stake in Acadia after the IPO. However, the company's IPO, which ultimately took place in May 2004, did not fare as well as expected and netted only US$35 million. At the time, the company had five drugs in development and was running two in human trials. The company had a subsequent round of stock offering in May 2007 which raised US$102 million.

In September 2020, Acadia Pharmaceuticals acquired clinical-stage biotechnology company CerSci Therapeutics.

Corporate governance

In 2001, the company's chief executive officer at the time, Leonard R. Borrmann, left Acadia to lead Maret Pharmaceuticals. He was succeeded by Uli Hacksell, who left Acadia to lead Cerecor at the beginning of 2016.

== References ==

Fonte: Wikipedia (Inglese), CC BY-SA 4.0 · Vedi su Wikipedia ↗

Wikidata ↗

ACAD Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane

Prezzo
$30.66
Capitalizzazione di Mercato
$5.22B
P/E (TTM)
13.3
EPS (TTM)
$2.30
Ricavi (TTM)
$1.07B
Rendimento div.
ROE
38.1%
D/E Debito/Patrimonio
Intervallo 52 sett.
$20 – $31

ACAD Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione

Performance decennale Andamento di ricavi, utile netto, margini e EPS

Ricavi e Utile Netto $1.07B
10-point trend, +6082.6%
2016-12-31 2025-12-31
EPS $2.30
6-point trend, +228.5%
2020-12-31 2025-12-31
Flusso di cassa libero $105M
10-point trend, +149.6%
2016-12-31 2025-12-31
Margini 36.5%
8-point trend, +14.6%
2016-12-31 2023-12-31

Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?

Metrica
Tendenza 5 anni
ACAD
Mediana dei peer
P/E (TTM)
5-point trend, +152.2%
13.3
13.2
P/S (TTM)
5-point trend, -45.3%
4.9
55.3
P/B
5-point trend, -46.7%
4.3
3.5
Price / FCF (Prezzo / FCF)
5-point trend, +246.0%
49.7

Redditività Margini lordi, operativi e netti; ROE, ROA, ROIC

Metrica
Tendenza 5 anni
ACAD
Mediana dei peer
Operating Margin (Margine Operativo)
5-point trend, +127.8%
9.8%
Net Profit Margin (Margine di Profitto Netto)
5-point trend, +205.2%
36.5%
-151.2%
ROA
5-point trend, +225.5%
28.4%
-42.2%
ROE
5-point trend, +225.9%
38.1%
-52.8%
ROIC
5-point trend, +176.1%
24.0%

Salute finanziaria Debito, liquidità, solvibilità — solidità del bilancio

Metrica
Tendenza 5 anni
ACAD
Mediana dei peer
Current Ratio (Rapporto corrente)
5-point trend, -40.4%
3.8
10.3
Quick Ratio
5-point trend, -51.0%
1.1

Crescita Crescita di ricavi, EPS e utile netto: YoY, CAGR 3Y, CAGR 5Y

Metrica
Tendenza 5 anni
ACAD
Mediana dei peer
Revenue YoY (Ricavi YoY)
5-point trend, +121.3%
11.9%
Revenue CAGR 3Y (CAGR Ricavi 3Y)
5-point trend, +121.3%
27.5%
Revenue CAGR 5Y (CAGR Ricavi 5Y)
5-point trend, +121.3%
19.4%
EPS YoY
5-point trend, +319.0%
69.1%
Net Income YoY (Utile Netto YoY)
5-point trend, +332.9%
72.7%

Metriche per Azione EPS, valore contabile per azione, flusso di cassa per azione, dividendo per azione

Metrica
Tendenza 5 anni
ACAD
Mediana dei peer
EPS (Diluted) (EPS (Diluito))
5-point trend, +319.0%
$2.30

Efficienza del Capitale Rotazione delle attività, rotazione delle scorte, rotazione dei crediti

Metrica
Tendenza 5 anni
ACAD
Mediana dei peer

ACAD Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo

COMPRA 27 analisti
  • Acquisto forte 7 25,9%
  • Compra 14 51,9%
  • Mantieni 5 18,5%
  • Vendi 1 3,7%
  • Vendita forte 0 0,0%

Target Price a 12 Mesi

20 analisti · 2026-08-18
Target mediano $36.00 +17,4%
Target medio $33.85 +10,4%

Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili

Sorpresa media
0.30%
Periodo EPS Actual EPS Stimato Sorpresa
30 Giugno 2026 $0.18 $0.06 0.12%
31 Marzo 2026 $0.02 $0.06 -0.04%
31 Dicembre 2025 $1.60 $0.14 1.5%
30 Settembre 2025 $0.42 $0.15 0.27%
30 Giugno 2025 $0.16 $0.14 0.02%
31 Marzo 2025 $0.11 $0.11 -0.00%

Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore

Ticker Capitalizzazione di Mercato P/E Rev YoY Margine Netto ROE Margine lordo
ACAD $4.55B 11.6 11.9% 36.5% 38.1%
DNTH $1.78B -9.8 -67.3% -7973.3% -40.8%
ERAS $1.06B -8.5 -35.7%
CAI $7.62B -8.4 97.0% -8.4% -13.2%
PTCT $6.19B 9.8 114.5% 39.4% -331.5%
TVTX $3.47B -131.8 110.5% -5.2% -34.6%
DYN $3.23B -5.6 -57.8%
PBLS
CELC $4.81B -26.3 -244.3%
RLAY $1.47B -5.3 53.4% -1800.6% -44.9%

Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario

Conto Economico 16
Dati annuali Conto Economico per ACAD
Metrica Tendenza 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +892820.8% $1.07B $958M $726M $517M $484M $442M $339M $224M $125M $17M $61.0K $120.0K
Cost of Revenue 10-point trend, +2794.2% $89M $82M $42M $10M $19M $10M $11M $12M $9M $3M · ·
Gross Profit 8-point trend, +4704.9% · · $685M $507M $473M $432M $328M $211M $116M $14M · ·
R&D Expense 12-point trend, +442.6% $329M $303M $352M $362M $239M $319M $240M $187M $149M $99M $74M $61M
SG&A Expense 12-point trend, +1576.1% $549M $488M $407M $369M $396M $389M $326M $266M $255M $186M $88M $33M
Operating Expenses 12-point trend, +935.6% $967M $727M $800M $741M $655M $728M $586M $471M $417M $290M $165M $93M
Operating Income 12-point trend, +212.4% $105M $231M $-73M $-224M $-170M $-287M $-247M $-247M $-292M $-273M $-165M $-93M
Other Non-op 8-point trend, +228.9% $2M $2M $5M $4M $2M $-997.0K $997.0K $-2M · · · ·
Pretax Income 12-point trend, +250.2% $139M $258M $-51M $-213M $-168M $-281M $-234M $-244M $-288M $-270M $-164M $-92M
Income Tax 12-point trend, -252096000.00 $-252M $32M $10M $3M $351.0K $611.0K $876.0K $1M $1M $1M $330.0K $0
Net Income 12-point trend, +522.8% $391M $226M $-61M $-216M $-168M $-282M $-235M $-245M $-289M $-271M $-164M $-92M
EPS (Basic) 6-point trend, +229.6% $2.32 $1.37 $-0.37 $-1.34 $-1.05 $-1.79 · · · · · ·
EPS (Diluted) 6-point trend, +228.5% $2.30 $1.36 $-0.37 $-1.34 $-1.05 $-1.79 · · · · · ·
Shares (Basic) 6-point trend, +106907.5% 168,356,000 165,717,000 163,819,000 161,683,000 160,493 157,331 · · · · · ·
Shares (Diluted) 6-point trend, +107901.0% 169,919,000 166,362,000 163,819,000 161,683,000 160,493 157,331 · · · · · ·
EBITDA 12-point trend, +212.4% $105M $231M $-73M $-224M $-170M $-287M $-247M $-247M $-292M $-273M $-165M $-93M
Stato Patrimoniale 25
Dati annuali Stato Patrimoniale per ACAD
Metrica Tendenza 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +187.3% $178M $320M $189M $115M $147M $326M $190M $135M $69M $164M $102M $62M
Receivables 10-point trend, +1957.5% $121M $99M $98M $62M $64M $48M $36M $26M $17M $6M · ·
Inventory 10-point trend, +2567.6% $111M $92M $40M $12M $14M $10M $6M $4M $5M $4M · ·
Prepaid Expense 12-point trend, +4996.4% $60M $56M $39M $21M $24M $26M $19M $21M $8M $8M $2M $1M
Current Assets 12-point trend, +227.2% $1.06B $938M $616M $508M $618M $718M $760M $526M $373M $548M $219M $325M
PP&E (Net) 12-point trend, +1258.2% $8M $4M $5M $6M $8M $9M $3M $3M $3M $3M $2M $553.0K
PP&E (Gross) 12-point trend, +531.1% $17M $14M $14M $14M $14M $13M $9M $8M $7M $6M $5M $3M
Accum. Depreciation 12-point trend, +343.2% $9M $10M $10M $8M $6M $4M $5M $4M $4M $3M $3M $2M
Intangibles 10-point trend, +1452.3% $109M $120M $65M $0 $0 $1M $3M $4M $6M $7M · ·
Other Non-current Assets 12-point trend, +1257.5% $4M $359.0K $476.0K $8M $4M $2M $3M $2M $354.0K $785.0K $329.0K $287.0K
Total Assets 12-point trend, +380.6% $1.56B $1.19B $749M $588M $700M $783M $783M $540M $385M $561M $222M $325M
Accounts Payable 12-point trend, +440.8% $11M $16M $18M $13M $7M $8M $7M $3M $9M $4M $2M $2M
Accrued Liabilities 12-point trend, +1826.6% $266M $379M $237M $113M $89M $97M $68M $56M $40M $36M $20M $14M
Current Liabilities 12-point trend, +1650.1% $277M $395M $254M $126M $96M $106M $75M $60M $49M $43M $22M $16M
Capital Leases 7-point trend, +537.5% $41M $42M $48M $53M $56M $44M $6M · · · · ·
Deferred Tax 7-point trend, +345.4% $11M $11M $12M $13M $14M $13M $3M · · · · ·
Other Non-current Liabilities 8-point trend, +1128.3% $19M $18M $15M $9M $7M $5M $3M $2M · · · ·
Total Liabilities 12-point trend, +2009.1% $337M $455M $317M $187M $159M $156M $84M $61M $49M $43M $22M $16M
Common Stock 12-point trend, +60.0% $16.0K $16.0K $16.0K $16.0K $16.0K $16.0K $15.0K $14.0K $12.0K $12.0K $10.0K $10.0K
Paid-in Capital 3-point trend, +79.8% · · · · · · · · · $1.45B $862M $808M
Retained Earnings 12-point trend, -264.0% $-1.81B $-2.20B $-2.43B $-2.37B $-2.15B $-1.99B $-1.70B $-1.47B $-1.22B $-934M $-663M $-498M
AOCI 12-point trend, +16155.6% $1M $292.0K $24.0K $-975.0K $-192.0K $36.0K $297.0K $-372.0K $-399.0K $106.0K $11.0K $-9.0K
Stockholders' Equity 12-point trend, +296.6% $1.23B $733M $432M $400M $541M $627M $699M $479M $335M $518M $200M $309M
Liabilities + Equity 12-point trend, +380.6% $1.56B $1.19B $749M $588M $700M $783M $783M $540M $385M $561M $222M $325M
Shares Outstanding 12-point trend, +70.2% 170,309,376 166,708,856 164,650,219 162,064,872 161,012,695 159,637,771 155,275,300 143,853,597 124,410,552 121,367,169 101,938,702 100,047,331
Flusso di cassa 13
Dati annuali Flusso di cassa per ACAD
Metrica Tendenza 202520242023202220212020201920182017201620152014
D&A · · · · · · · · · · · $206.0K
Stock-based Comp 12-point trend, +225.1% $52M $67M $66M $68M $64M $84M $82M $82M $76M $55M $40M $16M
Deferred Tax 5-point trend, -71417.4% $-250M $0 $0 $3M $351.0K · · · · · · ·
Amort. of Intangibles 12-point trend, +10889000.00 $11M $15M $4M $0 $1M $1M $1M $1M $1M $985.0K $0 $0
Operating Cash Flow 12-point trend, +265.3% $110M $158M $17M $-114M $-126M $-136M $-151M $-167M $-218M $-208M $-122M $-66M
CapEx 12-point trend, +2505.6% $5M $523.0K $50.0K $0 $1M $8M $1M $2M $812.0K $2M $2M $180.0K
Investing Cash Flow 10-point trend, -15.5% $-303M $-31M $32M $73M $-71M $193M $-166M $-71M $92M $-262M · ·
Stock Issued 12-point trend, -75.5% $50M $7M $25M $8M $18M $81M $372M $307M $31M $519M $15M $204M
Net Stock Activity 12-point trend, -75.5% $50M $7M $25M $8M $18M $81M $372M $307M $31M $519M $15M $204M
Financing Cash Flow 10-point trend, -90.7% $50M $7M $25M $8M $18M $81M $372M $307M $31M $534M · ·
Net Change in Cash 12-point trend, -384.8% $-143M $134M $74M $-33M $-179M $137M $55M $68M $-94M $63M $40M $50M
Taxes Paid 11-point trend, +5965.1% $25M $20M $6M $2M $1M $1M $2M $1M $1M $-365.0K $415.0K ·
Free Cash Flow 12-point trend, +257.8% $105M $157M $17M $-114M $-127M $-144M $-152M $-170M $-219M $-212M $-124M $-67M
Redditività 8
Dati annuali Redditività per ACAD
Metrica Tendenza 202520242023202220212020201920182017201620152014
Gross Margin 8-point trend, +14.6% · · 94.3% 98.0% 97.8% 97.7% 96.7% 94.5% 92.7% 82.2% · ·
Operating Margin 12-point trend, +100.0% 9.8% 24.1% -10.1% -43.2% -35.2% -64.9% -72.7% -110.6% -234.1% -1574.1% -269855.7% -77691.7%
Net Margin 12-point trend, +100.0% 36.5% 23.6% -8.4% -41.8% -34.7% -63.7% -69.4% -109.6% -231.7% -1565.9% -269578.7% -77062.5%
Pretax Margin 11-point trend, +100.0% 13.0% 26.9% -7.0% -41.3% -34.6% -63.6% -69.1% -109.0% -230.8% -1558.2% -269037.7% ·
EBITDA Margin 12-point trend, +100.0% 9.8% 24.1% -10.1% -43.2% -35.2% -64.9% -72.7% -110.6% -234.1% -1574.1% -269855.7% -77691.7%
ROA 12-point trend, +179.1% 28.4% 23.4% -9.2% -33.5% -22.6% -36.0% -35.5% -53.0% -61.2% -69.3% -60.1% -35.9%
ROE 12-point trend, +201.4% 38.1% 34.6% -15.4% -52.3% -30.3% -43.9% -33.9% -69.8% -67.8% -75.6% -64.6% -37.6%
ROIC 11-point trend, +129.1% 24.0% 27.6% -20.4% -56.5% -31.6% -45.8% -35.4% -51.9% -87.5% -52.9% -82.6% ·
Liquidità e Solvibilità 2
Dati annuali Liquidità e Solvibilità per ACAD
Metrica Tendenza 202520242023202220212020201920182017201620152014
Current Ratio 12-point trend, -81.3% 3.8 2.4 2.4 4.0 6.4 6.8 10.2 8.8 7.6 12.9 10.0 20.5
Quick Ratio 12-point trend, -72.4% 1.1 1.1 1.1 1.4 2.2 3.5 3.0 2.7 1.8 4.0 4.7 3.9
Efficienza 3
Dati annuali Efficienza per ACAD
Metrica Tendenza 202520242023202220212020201920182017201620152014
Asset Turnover 12-point trend, +155640.0% 0.8 1.0 1.1 0.8 0.7 0.6 0.5 0.5 0.3 0.0 0.0 0.0
Inventory Turnover 9-point trend, -40.5% 0.9 1.2 1.6 0.8 0.9 1.3 2.2 · 1.9 1.5 · ·
Receivables Turnover 10-point trend, +65.7% 9.7 9.7 9.1 8.2 8.6 10.5 11.0 10.3 10.7 5.9 · ·
Per Azione 5
Dati annuali Per Azione per ACAD
Metrica Tendenza 202520242023202220212020201920182017201620152014
Book Value / Share 12-point trend, +133.0% $7.21 $4.40 $2.62 $2.47 $3.36 $3.93 $4.50 $3.33 $2.69 $4.27 $1.96 $3.09
Revenue / Share 4-point trend, -99.8% $6.31 $5.76 $4434.39 $3199.07 · · · · · · · ·
Cash Flow / Share 4-point trend, +100.1% $0.65 $0.95 $101.95 $-705.30 · · · · · · · ·
Cash / Share 12-point trend, +68.8% $1.04 $1.92 $1.15 $0.71 $0.92 $2.04 $1.22 $0.94 $0.56 $1.35 $1.00 $0.62
EPS (TTM) 6-point trend, +228.5% $2.30 $1.36 $-0.37 $-1.34 $-1.05 $-1.79 · · · · · ·
Tassi di Crescita 5
Dati annuali Tassi di Crescita per ACAD
Metrica Tendenza 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +23.6% 11.9% 31.9% 40.5% 6.8% 9.6% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +52.4% 27.5% 25.5% 18.0% · · · · · · · · ·
Revenue CAGR 5Y 19.4% · · · · · · · · · · ·
EPS YoY 69.1% · · · · · · · · · · ·
Net Income YoY 72.7% · · · · · · · · · · ·
Valutazione (TTM) 10
Dati annuali Valutazione (TTM) per ACAD
Metrica Tendenza 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +892820.8% $1.07B $958M $726M $517M $484M $442M $339M $224M $125M $17M $61.0K $120.0K
Net Income TTM 12-point trend, +522.8% $391M $226M $-61M $-216M $-168M $-282M $-235M $-245M $-289M $-271M $-164M $-92M
Market Cap 12-point trend, +43.2% $4.55B $3.06B $5.16B $2.58B $3.76B $8.53B $6.64B $2.33B $3.75B $3.50B $3.63B $3.18B
P/E 6-point trend, +138.9% 11.6 13.5 -84.6 -11.9 -22.2 -29.9 · · · · · ·
P/S 12-point trend, -100.0% 4.2 3.2 7.1 5.0 7.8 19.3 19.6 10.4 30.0 202.0 59575.7 26470.9
P/B 12-point trend, -63.9% 3.7 4.2 11.9 6.4 6.9 13.6 9.5 4.9 11.2 6.8 18.2 10.3
P / Tangible Book 6-point trend, -70.2% 4.1 5.0 14.1 6.4 6.9 13.6 · · · · · ·
P / Cash Flow 12-point trend, +186.6% 41.4 19.4 308.7 -22.6 -29.9 -62.7 -44.0 -13.9 -17.2 -16.6 -29.8 -47.8
P / FCF 12-point trend, +190.7% 43.3 19.5 309.6 -22.6 -29.6 -59.4 -43.6 -13.7 -17.1 -16.5 -29.3 -47.7
Earnings Yield 6-point trend, +357.0% 8.6% 7.4% -1.2% -8.4% -4.5% -3.4% · · · · · ·

Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni

Conto Economico
2025-12-312024-12-312023-12-312022-12-312021-12-31
Ricavi $1.07B$958M$726M$517M$484M
Margine Lordo % 94.3%98.0%97.8%
Margine Operativo % 9.8%24.1%-10.1%-43.2%-35.2%
Utile netto $391M$226M$-61M$-216M$-168M
EPS Diluito $2.30$1.36$-0.37$-1.34$-1.05
Stato Patrimoniale
2025-12-312024-12-312023-12-312022-12-312021-12-31
Rapporto corrente 3.82.42.44.06.4
Quick Ratio 1.11.11.11.42.2
Flusso di cassa
2025-12-312024-12-312023-12-312022-12-312021-12-31
Flusso di cassa libero $105M$157M$17M$-114M$-127M

Ultime notizie Notizie recenti che menzionano questa società

Segnali di trading Segnali recenti di acquisto/vendita con prezzo di entrata e rapporto rischio/rendimento

Le Mie Metriche La tua watchlist personale — righe selezionate da Fondamentali Completi

📊

Scegli le metriche che contano per te — fai clic sul ➕ accanto a qualsiasi riga nei Fondamentali Completi sopra.

La tua selezione è salvata e ti segue su tutti i ticker.

Proprietari istituzionali (13F) 388 filer · $3.3B totale · Aggiornato al 30 Giugno 2026

Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.

Attività istituzionale — Q2 2026 vs trimestre precedente
Nuove posizioni Posizioni chiuse Aumentato Diminuito Variazione netta delle azioni
56 (+10 vs trimestre precedente) 37 (+10 vs trimestre precedente) 136 (+11 vs trimestre precedente) 100 (-13 vs trimestre precedente) +17.3M

Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.

Istituzione Valore Azioni % di 13F tracciati Tipo
BAKER BROS. ADVISORS LP $1.085.696.471 42.912.904 32,71% Azioni
STATE STREET CORP $229.628.164 9.076.212 6,92% Azioni
VANGUARD PORTFOLIO MANAGEMENT LLC $223.612.785 8.838.450 6,74% Azioni
RTW INVESTMENTS, LP $180.756.457 7.144.524 5,45% Azioni
VANGUARD CAPITAL MANAGEMENT LLC $145.822.875 5.763.750 4,39% Azioni
DIMENSIONAL FUND ADVISORS LP $88.971.384 3.516.656 2,68% Azioni
GEODE CAPITAL MANAGEMENT, LLC $73.088.127 2.888.204 2,20% Azioni
Palo Alto Investors LP $72.461.629 2.864.096 2,18% Azioni
Qube Research & Technologies Ltd $61.899.233 2.446.610 1,86% Azioni
Point72 Asset Management, L.P. $61.559.150 2.433.168 1,85% Azioni
CITADEL ADVISORS LLC $53.414.195 2.111.233 1,61% Azioni
Pictet Asset Management Holding SA $50.146.450 1.983.198 1,51% Azioni
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $49.826.959 1.969.445 1,50% Azioni
MARSHALL WACE, LLP $44.649.289 1.764.794 1,35% Azioni
BRAIDWELL LP $41.653.895 1.646.399 1,25% Azioni
NORGES BANK $41.069.692 1.623.308 1,24% Azioni
Frazier Life Sciences Management, L.P. $36.386.409 1.438.198 1,10% Azioni
Artisan Partners Limited Partnership $33.525.890 1.325.134 1,01% Azioni
RENAISSANCE TECHNOLOGIES LLC $32.449.679 1.282.596 0,98% Azioni
GOLDMAN SACHS GROUP INC $32.070.584 1.267.612 0,97% Azioni
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $30.520.301 1.206.336 0,92% Azioni
D. E. Shaw & Co., Inc. $28.330.257 1.119.773 0,85% Azioni
Allspring Global Investments Holdings, LLC $26.143.513 1.037.441 0,79% Azioni
TWO SIGMA INVESTMENTS, LP $23.452.898 926.992 0,71% Azioni
VANGUARD FIDUCIARY TRUST CO $23.082.961 912.370 0,70% Azioni
BANK OF AMERICA CORP /DE/ $21.702.062 857.789 0,65% Azioni
PANAGORA ASSET MANAGEMENT INC $17.985.922 710.906 0,54% Azioni
Fisher Asset Management, LLC $17.690.535 699.230 0,53% Azioni
Allianz Asset Management GmbH $15.730.341 706.664 0,47% Azioni
RICE HALL JAMES & ASSOCIATES, LLC $15.657.841 618.887 0,47% Azioni
MILLENNIUM MANAGEMENT LLC $14.925.077 589.924 0,45% Azioni
MANUFACTURERS LIFE INSURANCE COMPANY, THE $14.771.456 583.852 0,45% Azioni
ADAGE CAPITAL PARTNERS GP, L.L.C. $12.903.000 510.000 0,39% Azioni
Hudson Bay Capital Management LP $11.764.500 465.000 0,35% Azioni
GLENMEDE TRUST CO NA $11.656.544 460.733 0,35% Azioni
JUPITER ASSET MANAGEMENT LTD $11.599.190 458.466 0,35% Azioni
Public Sector Pension Investment Board $11.014.988 435.375 0,33% Azioni
MACKENZIE FINANCIAL CORP $10.646.872 420.825 0,32% Azioni
Ishara Investments LP $10.373.000 410.000 0,31% Azioni
TWO SIGMA ADVISERS, LP $9.888.042 370.200 0,30% Azioni
Balyasny Asset Management L.P. $9.817.007 388.024 0,30% Azioni
BlackRock, Inc. $9.281.482 366.857 0,28% Azioni
SPHERA FUNDS MANAGEMENT LTD. $9.020.310 356.534 0,27% Azioni
AMERIPRISE FINANCIAL INC $8.039.177 317.754 0,24% Azioni
PRUDENTIAL FINANCIAL INC $7.985.313 315.625 0,24% Azioni
Alyeska Investment Group, L.P. $7.850.261 310.287 0,24% Azioni
RHUMBLINE ADVISERS $7.663.389 302.902 0,23% Azioni
Schonfeld Strategic Advisors LLC $7.189.171 284.157 0,22% Azioni
Edgestream Partners, L.P. $7.167.515 283.301 0,22% Azioni
Logos Global Management LP $6.325.000 250.000 0,19% Azioni
LAZARD ASSET MANAGEMENT LLC $6.263.496 247.569 0,19% Azioni
FMR LLC $6.052.317 239.222 0,18% Azioni
Swiss National Bank $5.841.871 230.904 0,18% Azioni
VICTORY CAPITAL MANAGEMENT INC $5.432.213 214.712 0,16% Azioni
ALPS ADVISORS INC $4.985.340 197.049 0,15% Azioni
ENVESTNET ASSET MANAGEMENT INC $4.926.239 194.713 0,15% Azioni
Legal & General Group Plc $4.918.245 194.397 0,15% Azioni
FIRST TRUST ADVISORS LP $4.664.965 184.386 0,14% Azioni
NEW YORK STATE COMMON RETIREMENT FUND $4.364.807 172.522 0,13% Azioni
Birchview Capital, LP $4.326.300 171.000 0,13% Azioni
MARTINGALE ASSET MANAGEMENT L P $4.247.693 167.893 0,13% Azioni
Tetragon Partners GP Ltd $4.247.238 167.875 0,13% Azioni
GREAT LAKES ADVISORS, LLC $3.822.526 151.088 0,12% Azioni
AMERICAN CENTURY COMPANIES INC $3.635.306 143.688 0,11% Azioni
STEMPOINT CAPITAL LP $3.622.125 143.167 0,11% Azioni
ALLIANCEBERNSTEIN L.P. $3.585.329 161.066 0,11% Azioni
Squarepoint Ops LLC $3.542.329 140.013 0,11% Azioni
ORBIMED ADVISORS LLC $3.466.100 137.000 0,10% Azioni
Erste Asset Management GmbH $3.369.240 133.700 0,10% Azioni
Emerald Investment Advisers, LLC $3.333.326 131.752 0,10% Azioni
Caption Management, LLC $3.289.000 130.000 0,10% Opzione Put
VANGUARD ASSET MANAGEMENT, Ltd $3.130.217 123.724 0,09% Azioni
WELLS FARGO & COMPANY/MN $3.084.475 121.916 0,09% Azioni
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $3.077.311 138.244 0,09% Azioni
Longaeva Partners L.P. $2.968.145 117.318 0,09% Azioni
JACOBS LEVY EQUITY MANAGEMENT, INC $2.948.791 116.553 0,09% Azioni
Trexquant Investment LP $2.935.357 116.022 0,09% Azioni
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $2.909.778 115.011 0,09% Azioni
JONES FINANCIAL COMPANIES LLLP $2.868.477 113.289 0,09% Azioni
Rafferty Asset Management, LLC $2.789.426 110.254 0,08% Azioni
Nan Fung Group Holdings Ltd $2.605.495 102.984 0,08% Azioni
RAYMOND JAMES FINANCIAL INC $2.406.232 95.108 0,07% Azioni
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $2.344.000 92.648 0,07% Azioni
ROYCE & ASSOCIATES LP $2.324.691 91.885 0,07% Azioni
HOHIMER WEALTH MANAGEMENT, LLC $2.322.540 91.800 0,07% Azioni
Point72 Europe (London) LLP $2.305.047 108.015 0,07% Azioni
VIRGINIA RETIREMENT SYSTEMS ET Al $2.134.076 79.898 0,06% Azioni
Campbell & CO Investment Adviser LLC $2.108.527 83.341 0,06% Azioni
Verdad Advisers, LP $2.090.514 82.629 0,06% Azioni
VOYA INVESTMENT MANAGEMENT LLC $2.072.576 81.920 0,06% Azioni
CITADEL ADVISORS LLC $2.049.300 81.000 0,06% Opzione Call
GUGGENHEIM CAPITAL LLC $1.979.776 78.252 0,06% Azioni
WESBANCO BANK INC $1.978.460 78.200 0,06% Azioni
Phocas Financial Corp. $1.954.299 77.245 0,06% Azioni
MetLife Investment Management, LLC $1.899.043 75.061 0,06% Azioni
STATE OF WISCONSIN INVESTMENT BOARD $1.850.493 73.142 0,06% Azioni
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1.788.331 70.685 0,05% Azioni
Freestone Grove Partners LP $1.755.643 69.393 0,05% Azioni
CenterBook Partners LP $1.743.878 68.928 0,05% Azioni
CANADA PENSION PLAN INVESTMENT BOARD $1.722.930 68.100 0,05% Azioni

Insider aziendali 37 insider · 19 dirigenti · 19 direttori

Insider Ruolo Ultima attività Azioni possedute Acquisti 12m Vendite 12m Netto 12m
Stephen Davis CEO 06 Gennaio 2024 M 96.521 0 0 $0
Uli Hacksell CEO 25 Marzo 2011 A 69.916 0 0 $0
Elena Ridloff EVP and CFO 29 Aprile 2021 M 10.553 0 0 $0
Todd S. Young EVP AND CFO 15 Ottobre 2018 A 0 0 $0
Thomas H Aasen Exec. VP, CFO & CBO 25 Marzo 2011 A 13.899 0 0 $0
Srdjan R. Stankovic President 21 Novembre 2022 M 61.234 0 0 $0
Mark R Brann President & CSO 16 Giugno 2006 S 317.756 0 0 $0
Brendan Teehan EVP, COO, Head of Commercial 06 Gennaio 2024 M 30.949 0 0 $0
Elizabeth H.Z. Thompson EVP, Head of Research & Dev 29 Luglio 2026 M 18.994 0 2 $-432.662
James Kihara PRINCIPAL ACCOUNTING OFFICER 26 Giugno 2026 S 13.088 0 2 $-412.253
Austin D. Kim EVP,General Counsel, Secretary 06 Gennaio 2024 M 46.901 0 0 $0
Douglas J Williamson Executive VP, Research & Dev 10 Febbraio 2023 A 0 0 $0
Michael J. Yang EVP and CCO 06 Gennaio 2021 M 8.059 0 0 $0
Eric Alejandro Miller Controller & PAO 15 Ottobre 2019 M 270 0 0 $0
Glenn Baity VP, GC & Sec. 25 Marzo 2011 A 0 0 $0
Roger Mills Executive VP, Development 25 Marzo 2011 A 0 0 $0
Bo-Ragnar Tolf VP/Mg. Dir. ACADIA Pharma AB 08 Luglio 2009 M 20.000 0 0 $0
Brian Lundstrom Sr. VP, Bus. Development 07 Marzo 2008 A 0 0 0 $0
Robert E Davis Exec. VP, Drug Discovery 11 Marzo 2005 A 0 0 $0
Adora Ndu Direttore 29 Maggio 2026 A 32.908 0 0 $0
Elizabeth A. Garofalo Direttore 29 Maggio 2026 A 33.489 0 0 $0
Jonathan Poole Direttore 29 Maggio 2026 A 2.010 0 0 $0
James M Daly Direttore 29 Maggio 2026 A 12.148 0 0 $0
Laura Brege Direttore 29 Maggio 2026 A 23.202 0 0 $0
Edmund Harrigan Direttore 29 Maggio 2026 A 43.148 0 0 $0
Daniel B Soland Direttore 01 Giugno 2023 A 28.002 0 0 $0
Torsten Rasmussen Direttore 11 Giugno 2010 A 4.000 0 0 $0
Leslie L Iversen Direttore 11 Giugno 2010 A 9.000 0 0 $0
Mary Ann Gray Direttore 11 Giugno 2010 A 0 0 $0
Michael T Borer Direttore 11 Giugno 2010 A 0 0 $0
Lester J Ph D Kaplan Direttore 11 Giugno 2010 A 4.000 0 0 $0
Gordon M Binder Direttore 12 Giugno 2009 A 14.364 0 0 $0
Alan G Walton Direttore 12 Giugno 2009 A 25.979 0 0 $0
Martien Van Osch Direttore 10 Giugno 2005 A 1.168.892 0 0 $0
GORDON CARL L Direttore 20 Aprile 2005 A 774.006 0 0 $0
Mark C. Schneyer 06 Agosto 2026 M 67.828 0 3 $-587.248
John Joseph Kaiser 20 Ottobre 2008 A 0 0 $0

Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato

Attivisti e proprietari del 5%+ 6 partecipazioni

Investitori che hanno depositato SEC Schedule 13D — proprietà effettiva superiore al 5% con l'intento di influenzare l'emittente (partecipazioni attiviste, campagne per il consiglio di amministrazione, M&A). Ogni riga mostra lo stato più recente noto della posizione di quel depositante.

Depositante Depositato Partecipazione Stato Scopo Deposito
Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker, Felix J. Baker, FBB3 LLC ×14 depositi 26 Febbraio 2026 25,40% Modifica SEC
Baker Bros. Advisors, LLC, Felix J. Baker, Julian C. Baker ×4 depositi 06 Giugno 2013 Deposito iniziale SEC
Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata 02 Maggio 2005 Deposito iniziale SEC
Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata 02 Maggio 2005 Deposito iniziale SEC
Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata 02 Maggio 2005 Deposito iniziale SEC
Oxford Bioscience Partners IV L.P., mRNA Fund II L.P., OBP Management IV L.P., Jeffrey T. Barnes, Mark P. Carthy, Jonathan J. Fleming, Michael E. Lytton, Alan G. Walton 29 Aprile 2005 Deposito iniziale Investimento passivo SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Proprietà ETF Posseduti da 77 ETF

Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.

Fondo Peso Unità Aggiornato al Fonte
IBRN · iShares Trust 4,89% 13.265 SH 08 Agosto 2026 Giornaliero
PBE · Invesco Exchange-Traded Fund Trust 3,29% 407.914 SH 08 Agosto 2026 Giornaliero
SBIO · ALPS ETF Trust 2,35% 175.740 NS 31 Maggio 2026 N-PORT
PSCH · Invesco Exchange-Traded Fund Trust … 1,87% 109.972 SH 08 Agosto 2026 Giornaliero
BBP · ETFis Series Trust I 1,32% 34.855 NS 30 Aprile 2026 N-PORT
RZG · Invesco Exchange-Traded Fund Trust 1,25% 59.514 SH 08 Agosto 2026 Giornaliero
LABU · Direxion Shares ETF Trust 0,85% 195.542 NS 30 Aprile 2026 N-PORT
ROSC · Lattice Strategies Trust 0,56% 13.607 NS 30 Aprile 2026 N-PORT
IJT · iShares Trust 0,40% 1.176.933 SH 08 Agosto 2026 Giornaliero
OASC · Unified Series Trust 0,39% 15.269 NS 31 Maggio 2026 N-PORT
IBB · iShares Trust 0,37% 1.239.145 SH 08 Agosto 2026 Giornaliero
VIOG · VANGUARD ADMIRAL FUNDS 0,35% 150.827 SH 08 Agosto 2026 Giornaliero
IBBQ · Invesco Exchange-Traded Fund Trust … 0,34% 9.317 SH 08 Agosto 2026 Giornaliero
FNY · First Trust Exchange-Traded AlphaDE… 0,27% 61.606 NS 30 Aprile 2026 N-PORT
BFOR · ALPS ETF Trust 0,24% 24.003 NS 31 Maggio 2026 N-PORT
QVMS · Invesco Exchange-Traded Fund Trust … 0,23% 20.369 SH 08 Agosto 2026 Giornaliero
IWO · iShares Trust 0,23% 1.166.817 SH 08 Agosto 2026 Giornaliero
XJR · iShares Trust 0,23% 14.974 SH 08 Agosto 2026 Giornaliero
GSSC · Goldman Sachs ETF Trust 0,20% 89.945 NS 31 Maggio 2026 N-PORT
IJR · iShares Trust 0,20% 7.728.433 SH 08 Agosto 2026 Giornaliero
VTWG · VANGUARD SCOTTSDALE FUNDS 0,19% 137.860 SH 08 Agosto 2026 Giornaliero
BIB · ProShares Trust 0,19% 6.303 NS 31 Maggio 2026 N-PORT
VIOO · VANGUARD ADMIRAL FUNDS 0,17% 443.221 SH 08 Agosto 2026 Giornaliero
BKSE · BNY Mellon ETF Trust 0,17% 6.035 NS 30 Aprile 2026 N-PORT
SMMV · iShares Trust 0,17% 17.063 SH 08 Agosto 2026 Giornaliero
SMLF · iShares Trust 0,15% 219.745 SH 08 Agosto 2026 Giornaliero
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0,15% 47.683 NS 30 Aprile 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0,14% 137.072 SH 08 Agosto 2026 Giornaliero
FNX · First Trust Exchange-Traded AlphaDE… 0,14% 81.552 NS 30 Aprile 2026 N-PORT
SAA · ProShares Trust 0,12% 1.498 NS 31 Maggio 2026 N-PORT
IWM · iShares Trust 0,12% 3.281.125 SH 08 Agosto 2026 Giornaliero
ISCG · iShares Trust 0,11% 39.884 SH 08 Agosto 2026 Giornaliero
VTWO · VANGUARD SCOTTSDALE FUNDS 0,10% 741.237 SH 08 Agosto 2026 Giornaliero
RWJ · Invesco Exchange-Traded Fund Trust … 0,09% 66.331 SH 08 Agosto 2026 Giornaliero
VBK · VANGUARD INDEX FUNDS 0,09% 1.699.377 SH 08 Agosto 2026 Giornaliero
AVSC · AMERICAN CENTURY ETF TRUST 0,09% 115.210 NS 31 Maggio 2026 N-PORT
DFAS · Dimensional ETF Trust 0,08% 526.641 NS 30 Aprile 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0,08% 16.957 NS 30 Aprile 2026 N-PORT
ITWO · ProShares Trust 0,07% 5.921 NS 31 Maggio 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0,06% 599.784 NS 31 Maggio 2026 N-PORT
ISCB · iShares Trust 0,06% 5.636 SH 08 Agosto 2026 Giornaliero
FHLC · FIDELITY COVINGTON TRUST 0,04% 54.956 NS 30 Aprile 2026 N-PORT
IEUS · iShares Trust 0,04% 7.411 SH 08 Agosto 2026 Giornaliero
SMDX · Tidal Trust III 0,04% 2.306 NS 30 Aprile 2026 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0,04% 4.033 SH 08 Agosto 2026 Giornaliero
UWM · ProShares Trust 0,04% 4.631 NS 31 Maggio 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0,04% 1.457.036 SH 08 Agosto 2026 Giornaliero
VB · VANGUARD INDEX FUNDS 0,04% 2.944.095 SH 08 Agosto 2026 Giornaliero
PDN · Invesco Exchange-Traded Fund Trust … 0,04% 14.209 SH 08 Agosto 2026 Giornaliero
VHT · VANGUARD WORLD FUND 0,04% 346.329 SH 08 Agosto 2026 Giornaliero