ALEC Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane

03

Prezzo $1.81

Capitalizzazione di Mercato (MRQ) $202M

P/E (TTM) -1.6

EPS (TTM) $-1.10

Ricavi (TTM) $14M

ROE (TTM) -385.1%

D/E Debito/Patrimonio (MRQ) -1.0

Intervallo 52 sett. $1–$3

ALEC Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione

04

intervallo

barre

La granularità delle barre si adatta al periodo selezionato — passa il mouse sul grafico per vedere apertura/massimo/minimo/chiusura di una barra.

Informazioni su Alector, Inc. - Common Stock Panoramica della società da Wikipedia

05 · wikidata

Wikidata ↗

settoreHealthcare industriaBiotechnology dipendenti103 paeseUS

Performance decennale Andamento di ricavi, utile netto, margini e EPS

06

Ricavi$21M

2017-12-31 → 2025-12-31

EPS$-1.39

2020-12-31 → 2025-12-31

Flusso di cassa libero$-184M

2019-12-31 → 2025-12-31

Margine netto-851.7%

2019-12-31 → 2025-12-31

Valutazione e Rapporti 07–12

Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?

Metrica	ALEC	media 5 anni	Mediana dei peer	Verdetto
P/E (TTM)	-1.6media 5 anni ≈-11.9	≈-11.9	·	·
P/S (TTM)	14.6media 5 anni ≈6.1	≈6.1	16.0	Sopravvalutato
P/B (MRQ)	-20.3media 5 anni ≈4.2	≈4.2	·	·
EV / EBITDA	0.3	·	·	·
Prezzo / FCF (TTM)	-1.3media 5 anni ≈-6.2	≈-6.2	·	·
Prezzo / Flusso di cassa (TTM)	-1.3media 5 anni ≈-7.4	≈-7.4	·	·
EV / Ricavi (TTM)	2.8	·	·	·
EV / FCF (TTM)	-0.2	·	·	·
Price / Tangible Book (Prezzo / Valore contabile tangibile)	6.6media 5 anni ≈4.2	≈4.2	·	·

La mediana dei peer viene calcolata su base standardizzata per metrica e potrebbe non corrispondere sempre alla base TTM/MRQ mostrata per questo titolo.

Redditività Margini lordi, operativi e netti; ROE, ROA, ROIC

Metrica	ALEC	media 5 anni	Mediana dei peer	Verdetto
Margine Operativo (TTM)	-914.1%media 5 anni ≈-232.6%	≈-232.6%	-1357.2%	Di prim'ordine
EBITDA Margin (Margine EBITDA)	-741.3%media 5 anni ≈-232.6%	≈-232.6%	-1356.6%	Di prim'ordine
Margine ante imposte (TTM)	-849.4%	·	-1167.4%	Di prim'ordine
Margine di Profitto Netto (TTM)	-851.7%media 5 anni ≈-209.8%	≈-209.8%	-1615.2%	Di prim'ordine
ROA (TTM)	-42.1%media 5 anni ≈-20.0%	≈-20.0%	-24.7%	Debole
ROE (TTM)	-385.1%media 5 anni ≈-106.8%	≈-106.8%	-24.6%	Debole
ROIC	-387.2%	·	-51.5%	Debole

Salute finanziaria Debito, liquidità, solvibilità — solidità del bilancio

Metrica	ALEC	media 5 anni	Mediana dei peer	Verdetto
Debito / Patrimonio Netto (MRQ)	-1.0	·	-0.2	Basso indebitamento
Rapporto corrente (MRQ)	5.3media 5 anni ≈4.7	≈4.7	7.9	Bassa liquidità
Quick Ratio	3.7media 5 anni ≈4.6	≈4.6	7.4	Bassa liquidità
Debito a lungo termine / Patrimonio netto (MRQ)	-0.0	·	·	·

Crescita Crescita di ricavi, EPS e utile netto: YoY, CAGR 3Y, CAGR 5Y

Metrica	ALEC	media 5 anni	Mediana dei peer	Verdetto
Revenue YoY (Ricavi YoY)	-79.1%media 5 anni ≈148.6%	≈148.6%	·	·
Revenue CAGR 3Y (CAGR Ricavi 3Y)	-46.0%media 5 anni ≈-0.35%	≈-0.35%	·	·
Revenue CAGR 5Y (CAGR Ricavi 5Y)	-0.05%	·	·	·

Metriche per Azione EPS, valore contabile per azione, flusso di cassa per azione, dividendo per azione

Metrica	ALEC	media 5 anni	Mediana dei peer	Verdetto
EPS (Diluted) (EPS (Diluito))	$-1.39media 5 anni ≈$-1.25	≈$-1.25	·	·
Revenue / Share (Ricavi / Azione)	$0.20media 5 anni ≈$1.01	≈$1.01	·	·
Cash Flow / Share (Flusso di cassa / Azione)	$-1.79media 5 anni ≈$-1.65	≈$-1.65	·	·
Cash / Share (Liquidità / Azione)	$0.60media 5 anni ≈$1.57	≈$1.57	·	·

Efficienza del Capitale Rotazione delle attività, rotazione delle scorte, rotazione dei crediti

Metrica	Tendenza 5 anni	ALEC	media 5 anni	Mediana dei peer	Verdetto
Asset Turnover (Rotazione delle attività)		0.1media 5 anni ≈0.2	≈0.2	0.1	Debole
Revenue / Employee (Ricavi / Dipendente)		≈$204.3K	·	·	·

valore · ≈ media 5 anni · mediana del settore · giudizio rispetto alla mediana

Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili

14

Sorpresa media 22.4%

Prossimo report Nov 04, 2026

Periodo	Rapporto	EPS Actual	EPS Stimato	Sorpresa
30 Giugno 2026	Ago 5, 2026	$-0.21	$-0.23	9.7%
31 Marzo 2026		$-0.21	$-0.35	39.9%
31 Dicembre 2025		$-0.34	$-0.39	13.1%
30 Settembre 2025		$-0.34	$-0.42	18.2%
30 Giugno 2025		$-0.30	$-0.47	36.1%
31 Marzo 2025		$-0.41	$-0.49	17.1%

Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario

15

Conto Economico 14

Metrica	2025	2024	2023	2022	2021	2020	2019	2018
Revenue	$21M	$101M	$97M	$134M	$207M	$21M	$21M	$28M
R&D Expense	$123M	$186M	$192M	$210M	$189M	$157M	$101M	$73M
SG&A Expense	$54M	$60M	$57M	$61M	$55M	$59M	$35M	$12M
Operating Expenses	$177M	$246M	$249M	$271M	$244M	$216M	$136M	$85M
Operating Income	$-156M	$-145M	$-152M	$-138M	$-37M	$-195M	$-114M	$-57M
Other Non-op	$13M	$26M	$27M	$8M	$1M	$5M	$9M	$5M
Pretax Income	$-143M	$-119M	$-125M	$-130M	·	·	·	·
Income Tax	$168.0K	$128.0K	$5M	$3M	$0	$0	$0	·
Net Income	$-143M	$-119M	$-130M	$-133M	$-36M	$-190M	$-105M	$-52M
EPS (Basic)	$-1.39	$-1.23	$-1.56	$-1.62	$-0.45	$-2.45	·	·
EPS (Diluted)	$-1.39	$-1.23	$-1.56	$-1.62	$-0.45	$-2.45	·	·
Shares (Basic)	102,998,978	96,588,177	83,733,730	82,467,587	80,416,936	77,758,806	·	·
Shares (Diluted)	102,998,978	96,588,177	83,733,730	82,467,587	80,416,936	77,758,806	·	·
EBITDA	$-156M	$-145M	$-152M	$-138M	$-37M	·	$-114M	·

Stato Patrimoniale 25

Metrica	2025	2024	2023	2022	2021	2020	2019	2018
Cash & Equivalents	$66M	$33M	$75M	$154M	$329M	$50M	$90M	$65M
Short-term Investments	$190M	$380M	$474M	$559M	$406M	$363M	$263M	$225M
Prepaid Expense	$10M	$11M	$17M	$11M	$7M	$8M	$4M	$3M
Current Assets	$266M	$425M	$566M	$726M	$750M	$422M	$357M	$293M
PP&E (Net)	$11M	$17M	$22M	$26M	$27M	$30M	$34M	$11M
PP&E (Gross)	$48M	$50M	$50M	$48M	$45M	$41M	$39M	$13M
Accum. Depreciation	$37M	$33M	$28M	$23M	$17M	$11M	$5M	$2M
Other Non-current Assets	$386.0K	$5M	$7M	$6M	$6M	$3M	$676.0K	$3M
Total Assets	$293M	$468M	$622M	$788M	$815M	$488M	$422M	$308M
Accounts Payable	$2M	$2M	$4M	$4M	$5M	$3M	$278.0K	$126.0K
Accrued Liabilities	$19M	$29M	$30M	$28M	$27M	$23M	$18M	$8M
Short-term Debt	$366.0K	$0	·	·	·	·	·	·
Current Liabilities	$70M	$125M	$178M	$94M	$140M	$68M	$62M	$48M
Capital Leases	$17M	$24M	$30M	$35M	$40M	$44M	$41M	·
Other Non-current Liabilities	$2M	$1M	$1M	$759.0K	$158.0K	$472.0K	$493.0K	$96.0K
Total Liabilities	$263M	$342M	$488M	$573M	$514M	$221M	$227M	$195M
Long-term Debt	$10M	$10M	·	·	·	·	·	·
Total Debt	$10M	$9M	·	·	·	·	·	·
Common Stock	$11.0K	$9.0K	$8.0K	$8.0K	$8.0K	$8.0K	$7.0K	$1.0K
Paid-in Capital	$1.00B	$956M	$844M	$799M	$748M	$677M	$414M	$17M
Retained Earnings	$-972M	$-829M	$-710M	$-580M	$-446M	$-410M	$-220M	$-114M
AOCI	$166.0K	$261.0K	$184.0K	$-5M	$-943.0K	$614.0K	$142.0K	$-42.0K
Stockholders' Equity	$31M	$127M	$134M	$214M	$301M	$268M	$195M	$-97M
Liabilities + Equity	$293M	$468M	$622M	$788M	$815M	$488M	$422M	$308M
Shares Outstanding	110,362,581	99,085,888	84,879,693	82,895,718	81,986,192	79,316,261	69,052,873	13,764,829

Flusso di cassa 12

Metrica	2025	2024	2023	2022	2021	2020	2019	2018
D&A	$6M	$5M	$6M	$6M	$6M	$6M	$4M	$1M
Stock-based Comp	$27M	$39M	$43M	$46M	$41M	$31M	$16M	$7M
Restructuring	$2M	$4M	$2M	·	·	·	·	·
Operating Cash Flow	$-184M	$-230M	$-184M	$-20M	$299M	$-167M	$-99M	$127M
CapEx	$41.0K	$1M	$2M	$4M	$3M	$5M	$15M	$2M
Investing Cash Flow	$197M	$107M	$102M	$-159M	$-50M	$-105M	$-49M	$-224M
Stock Issued	$20M	$71M	·	·	·	·	·	·
Net Stock Activity	$20M	·	·	·	·	·	·	·
Financing Cash Flow	$20M	$82M	$3M	$5M	$30M	$232M	$172M	$131M
Net Change in Cash	$33M	$-41M	$-80M	$-175M	$279M	$-40M	$24M	$34M
Taxes Paid	$-880.0K	$-100.0K	·	·	·	·	·	·
Free Cash Flow	$-184M	$-231M	$-187M	$-24M	$295M	·	$-115M	·

Redditività 7

Metrica	2025	2024	2023	2022	2021	2020	2019	2018
Operating Margin	-741.3%	-144.1%	-156.3%	-103.2%	-18.0%	·	-539.2%	·
Net Margin	-679.2%	-118.3%	-134.3%	-99.8%	-17.5%	·	-496.6%	·
Pretax Margin	-678.4%	-118.2%	·	·	·	·	·	·
EBITDA Margin	-741.3%	-144.1%	-156.3%	-103.2%	-18.0%	·	-539.2%	·
ROA	-37.5%	-21.8%	-18.5%	-16.6%	-5.6%	·	-28.9%	·
ROE	-280.7%	-96.9%	-87.9%	-57.0%	-11.4%	·	-51.0%	·
ROIC	-387.2%	-106.6%	·	·	·	·	·	·

Liquidità e Solvibilità 4

Metrica	2025	2024	2023	2022	2021	2020	2019	2018
Current Ratio	3.8	3.4	3.2	7.7	5.4	·	5.8	·
Quick Ratio	3.7	3.3	3.1	7.6	5.3	·	5.7	·
Debt / Equity	0.3	0.1	·	·	·	·	·	·
LT Debt / Equity	0.3	0.1	·	·	·	·	·	·

Efficienza 1

Metrica	Tendenza	2025	2024	2023	2022	2021	2020	2019	2018
Asset Turnover		0.1	0.2	0.1	0.2	0.3	·	0.1	·

Per Azione 5

Metrica	2025	2024	2023	2022	2021	2020	2019	2018
Book Value / Share	$0.28	$1.28	$1.58	$2.62	$3.79	·	$2.82	·
Revenue / Share	$0.20	$1.04	$1.16	$1.62	·	·	·	·
Cash Flow / Share	$-1.79	$-2.38	$-2.20	$-0.25	·	·	·	·
Cash / Share	$0.60	$0.33	$0.88	$1.88	$4.15	·	$1.30	·
EPS (TTM)	$-1.39	$-1.23	$-1.56	$-1.62	$-0.45	$-2.45	·	·

Tassi di Crescita 3

Metrica	2025	2024	2023	2022	2021	2020	2019	2018
Revenue YoY	-79.1%	3.6%	-27.3%	-35.5%	881.5%	·	·	·
Revenue CAGR 3Y	-46.0%	-21.4%	66.3%	·	·	·	·	·
Revenue CAGR 5Y	-0.05%	·	·	·	·	·	·	·

Valutazione (TTM) 14

Metrica	2025	2024	2023	2022	2021	2020	2019	2018
Revenue TTM	$21M	$101M	$97M	$134M	$207M	$21M	$21M	$28M
Net Income TTM	$-143M	$-119M	$-130M	$-133M	$-36M	$-190M	$-105M	$-52M
Market Cap	$172M	$187M	$677M	$757M	$1.64B	·	$1.19B	·
Enterprise Value	$-74M	$-217M	·	·	·	·	·	·
P/E	-1.1	-1.5	-5.1	-5.7	-45.9	-6.2	·	·
P/S	8.2	1.9	7.0	5.7	7.9	·	56.1	·
P/B	5.6	1.5	5.0	3.5	5.4	·	6.1	·
P / Tangible Book	5.6	1.5	5.0	3.5	5.4	4.5	·	·
P / Cash Flow	-0.9	-0.8	-3.7	-37.2	5.5	·	-12.0	·
P / FCF	-0.9	-0.8	-3.6	-31.0	5.5	·	-10.4	·
EV / EBITDA	0.5	1.5	·	·	·	·	·	·
EV / FCF	0.4	0.9	·	·	·	·	·	·
EV / Revenue	-3.5	-2.2	·	·	·	·	·	·
Earnings Yield	-89.1%	-65.1%	-19.6%	-17.5%	-2.2%	-16.2%	·	·

Conto Economico 14

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Revenue	$3M	$1M	$6M	$3M	$8M	$4M	$54M	$15M	$15M	$16M	$15M	$9M	$56M	$17M	$14M	$15M
R&D Expense	$19M	$18M	$32M	$29M	$28M	$34M	$46M	$48M	$46M	$45M	$48M	$46M	$46M	$52M	$54M	$48M
SG&A Expense	$8M	$8M	$13M	$12M	$14M	$15M	$15M	$16M	$14M	$14M	$15M	$13M	$14M	$15M	$15M	$14M
Operating Expenses	$28M	$26M	$46M	$41M	$42M	$48M	$61M	$64M	$61M	$60M	$63M	$60M	$60M	$67M	$70M	$63M
Operating Income	$-24M	$-25M	$-40M	$-38M	$-34M	$-45M	$-7M	$-48M	$-46M	$-44M	$-47M	$-51M	$-4M	$-50M	$-55M	$-48M
Other Non-op	$2M	$2M	$2M	$3M	$4M	$4M	$5M	$6M	$7M	$8M	$8M	$7M	$6M	$5M	$4M	$2M
Pretax Income	$-23M	$-23M	$-37M	$-35M	$-31M	$-40M	$-2M	$-42M	$-39M	$-36M	·	·	·	·	·	·
Income Tax	$130.0K	$0	$168.0K	$0	$0	$0	$48.0K	$0	$73.0K	$7.0K	$2M	$1M	$1M	$901.0K	$721.0K	$733.0K
Net Income	$-23M	$-23M	$-37M	$-35M	$-31M	$-40M	$-2M	$-42M	$-39M	$-36M	$-41M	$-44M	$1M	$-46M	$-52M	$-46M
EPS (Basic)	$-0.21	$-0.21	$-0.34	$-0.34	$-0.30	$-0.41	$-0.02	$-0.43	$-0.40	$-0.38	$-0.50	$-0.53	$0.02	$-0.55	$-0.64	$-0.56
EPS (Diluted)	$-0.21	$-0.21	$-0.34	$-0.34	$-0.30	$-0.41	$-0.02	$-0.43	$-0.40	$-0.38	$-0.50	$-0.53	$0.02	$-0.55	$-0.64	$-0.56
Shares (Basic)	111,224,116	110,590,014	·	102,597,601	100,371,632	99,398,200	·	97,519,595	96,674,921	93,810,177	·	83,927,961	83,497,125	83,102,296	·	82,602,842
Shares (Diluted)	111,224,116	110,590,014	·	102,597,601	100,371,632	99,398,200	·	97,519,595	96,674,921	93,810,177	·	83,927,961	83,566,293	83,102,296	·	82,602,842
EBITDA	$-24M	$-25M	·	$-38M	$-34M	$-45M	·	$-48M	$-46M	$-44M	·	$-51M	$-4M	$-50M	·	$-48M

Stato Patrimoniale 25

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Cash & Equivalents	$60M	$77M	$66M	$77M	$45M	$38M	$33M	$37M	$48M	$73M	$75M	$102M	$132M	$196M	·	$184M
Short-term Investments	$113M	$130M	$190M	$215M	$263M	$317M	$380M	$420M	$456M	$490M	$474M	$487M	$499M	$474M	·	$574M
Prepaid Expense	$7M	$9M	$10M	$9M	$12M	$12M	$11M	$12M	$16M	$19M	$17M	$14M	$10M	$12M	·	$10M
Current Assets	$180M	$215M	$266M	$300M	$319M	$367M	$425M	$469M	$520M	$581M	$566M	$613M	$648M	$686M	·	$775M
PP&E (Net)	$9M	$10M	$11M	$13M	$14M	$16M	$17M	$18M	$20M	$21M	$22M	$23M	$24M	$25M	·	$26M
PP&E (Gross)	·	·	$48M	·	·	·	$50M	·	·	·	$50M	·	·	·	·	·
Accum. Depreciation	·	·	$37M	·	·	·	$33M	·	·	·	$28M	·	·	·	·	·
Other Non-current Assets	$353.0K	$369.0K	$386.0K	$4M	$4M	$5M	$5M	$6M	$6M	$7M	$7M	$9M	$9M	$9M	·	$6M
Total Assets	$203M	$240M	$293M	$335M	$356M	$408M	$468M	$516M	$571M	$635M	$622M	$672M	$709M	$748M	·	$837M
Accounts Payable	$2M	$1M	$2M	$5M	$2M	$2M	$2M	$5M	$4M	$5M	$4M	$5M	$5M	$3M	·	$5M
Accrued Liabilities	$7M	$11M	$19M	$18M	$14M	$17M	$29M	$26M	$23M	$19M	$30M	$30M	$23M	$19M	·	$23M
Short-term Debt	·	$1M	$366.0K	·	·	·	$0	·	·	·	·	·	·	·	·	·
Current Liabilities	$34M	$41M	$70M	$80M	$84M	$110M	$125M	$143M	$148M	$165M	$178M	$155M	$132M	$99M	·	$161M
Capital Leases	$14M	$16M	$17M	$19M	$21M	$23M	$24M	$26M	$28M	$29M	$30M	$32M	$33M	$34M	·	$36M
Other Non-current Liabilities	$2M	$2M	$2M	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$898.0K	$898.0K	$898.0K	·	$233.0K
Total Liabilities	$213M	$230M	$263M	$278M	$285M	$314M	$342M	$397M	$420M	$457M	$488M	$510M	$512M	$565M	·	$584M
Long-term Debt	$10M	·	$10M	·	·	·	·	·	·	·	·	·	·	·	·	·
Total Debt	$10M	$10M	·	$10M	$10M	$9M	·	·	·	·	·	·	·	·	·	·
Common Stock	$11.0K	$11.0K	$11.0K	$10.0K	$9.0K	$9.0K	$9.0K	$9.0K	$9.0K	$9.0K	$8.0K	$8.0K	$8.0K	$8.0K	·	$8.0K
Paid-in Capital	$1.01B	$1.01B	$1.00B	$992M	$971M	$964M	$956M	$945M	$936M	$925M	$844M	$832M	$822M	$811M	·	$787M
Retained Earnings	$-1.02B	$-995M	$-972M	$-935M	$-900M	$-870M	$-829M	$-827M	$-785M	$-746M	$-710M	$-669M	$-624M	$-626M	·	$-527M
AOCI	$-126.0K	$-104.0K	$166.0K	$197.0K	$96.0K	$191.0K	$261.0K	$931.0K	$-620.0K	$-403.0K	$184.0K	$-721.0K	$-1M	$-2M	·	$-7M
Stockholders' Equity	$-10M	$10M	$31M	$58M	$71M	$95M	$127M	$119M	$151M	$179M	$134M	$163M	$196M	$183M	$214M	$253M
Liabilities + Equity	$203M	$240M	$293M	$335M	$356M	$408M	$468M	$516M	$571M	$635M	$622M	$672M	$709M	$748M	·	$837M
Shares Outstanding	111,656,805	111,025,187	110,362,581	107,446,056	101,212,329	99,992,600	99,085,888	97,929,897	97,321,062	96,384,562	84,879,693	84,136,381	83,830,300	83,351,778	82,895,718	81,986,192

Flusso di cassa 10

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
D&A	$1M	$1M	$1M	$1M	$2M	$984.0K	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$1M
Stock-based Comp	$3M	$3M	$5M	$6M	$7M	$8M	$10M	$9M	$10M	$10M	$12M	$10M	$10M	$11M	$11M	$11M
Restructuring	$700.0K	$-300.0K	$100.0K	$-100.0K	$0	$2M	·	·	·	·	·	·	·	·	·	·
Operating Cash Flow	$-34M	$-50M	$-42M	$-33M	$-49M	$-61M	$-55M	$-51M	$-63M	$-61M	$-46M	$-47M	$-43M	$-49M	$-49M	$-49M
CapEx	$31.0K	$118.0K	$0	$11.0K	$10.0K	$20.0K	$173.0K	$212.0K	$337.0K	$533.0K	$233.0K	$-94.0K	$1M	$1M	$766.0K	$2M
Investing Cash Flow	$17M	$61M	$26M	$50M	$56M	$66M	$41M	$40M	$37M	$-12M	$18M	$17M	$-22M	$89M	$18M	$61M
Stock Issued	·	·	$5M	·	·	·	$0	·	·	·	·	·	·	·	·	·
Financing Cash Flow	$50.0K	$25.0K	$5M	$15M	$122.0K	$0	$10M	$0	$644.0K	$71M	$590.0K	$0	$881.0K	$1M	$636.0K	$489.0K
Net Change in Cash	$-17M	$11M	$-11M	$32M	$7M	$5M	$-4M	$-10M	$-25M	$-2M	$-27M	$-30M	$-64M	$41M	$-30M	$12M
Free Cash Flow	·	$-50M	·	·	·	$-61M	·	·	·	$-62M	·	·	·	$-50M	·	·

Redditività 7

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Operating Margin	-734.7%	-2382.3%	·	-1153.6%	-433.5%	-1208.0%	·	-315.7%	-302.4%	-275.0%	·	-555.3%	-6.4%	-302.8%	·	-321.5%
Net Margin	-692.5%	-2192.2%	·	-1063.4%	-387.7%	-1093.8%	·	-275.2%	-256.4%	-227.0%	·	-488.2%	2.5%	-277.1%	·	-310.7%
Pretax Margin	-688.6%	-2192.2%	·	-1063.4%	-387.7%	-1094.6%	·	·	·	·	·	·	·	·	·	·
EBITDA Margin	-734.7%	-2382.3%	·	-1153.6%	-433.5%	-1208.0%	·	-315.7%	-302.4%	-275.0%	·	-555.3%	-6.4%	-302.8%	·	-321.5%
ROA	-8.2%	-7.1%	·	-8.1%	-6.6%	-7.8%	·	-7.1%	-6.0%	-5.2%	·	-5.9%	0.17%	-5.4%	·	-5.5%
ROE	-75.1%	-43.7%	·	-39.2%	-27.5%	-29.6%	·	-30.0%	-22.3%	-19.9%	·	-21.4%	0.57%	-20.4%	·	-15.7%
ROIC	20108.0%	-123.7%	·	-55.9%	-42.3%	-43.0%	·	·	·	·	·	·	·	·	·	·

Liquidità e Solvibilità 4

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Current Ratio	5.3	5.3	·	3.8	3.8	3.3	·	3.3	3.5	3.5	·	3.9	4.9	6.9	·	4.8
Quick Ratio	5.0	5.0	·	3.6	3.6	3.2	·	3.2	3.4	3.4	·	3.8	4.8	6.7	·	4.7
Debt / Equity	-1.0	0.9	·	0.2	0.1	0.1	·	·	·	·	·	·	·	·	·	·
LT Debt / Equity	0.0	0.8	·	0.2	0.1	0.1	·	·	·	·	·	·	·	·	·	·

Efficienza 1

Metrica	Tendenza	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Asset Turnover		0.0	0.0	·	0.0	0.0	0.0	·	0.0	0.0	0.0	·	0.0	0.1	0.0	·	0.0

Per Azione 5

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Book Value / Share	$-0.09	$0.09	·	$0.54	$0.70	$0.95	·	$1.21	$1.55	$1.86	·	$1.93	$2.34	$2.20	·	$3.09
Revenue / Share	$0.03	$0.01	·	$0.03	$0.08	$0.04	·	$0.16	$0.16	$0.17	·	$0.11	$0.67	$0.20	·	$0.18
Cash Flow / Share	·	$-0.45	·	·	·	$-0.61	·	·	·	$-0.65	·	·	·	$-0.58	·	·
Cash / Share	$0.54	$0.69	·	$0.71	$0.44	$0.38	·	$0.38	$0.49	$0.75	·	$1.21	$1.57	$2.35	·	$2.25
EPS (TTM)	$-1.10	$-1.19	·	$-1.07	$-1.16	$-1.26	·	$-1.71	$-1.81	$-1.39	·	$-1.70	$-1.73	$-1.63	·	$-1.66

Valutazione (TTM) 11

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Revenue TTM	$14M	$18M	·	$69M	$81M	$88M	·	$62M	$55M	$96M	·	$96M	$102M	$126M	·	$133M
Net Income TTM	$-118M	$-125M	·	$-108M	$-115M	$-123M	·	$-158M	$-161M	$-121M	·	$-141M	$-143M	$-135M	·	$-136M
Market Cap	$224M	$239M	·	$318M	$142M	$123M	·	$456M	$442M	$580M	·	$545M	$504M	$516M	·	$776M
Enterprise Value	$61M	$42M	·	$37M	$-156M	$-222M	·	·	·	·	·	·	·	·	·	·
P/E	-1.8	-1.8	·	-2.8	-1.2	-1.0	·	-2.7	-2.5	-4.3	·	-3.8	-3.5	-3.8	·	-5.7
P/S	16.2	13.0	·	4.6	1.7	1.4	·	7.4	8.0	6.0	·	5.7	4.9	4.1	·	5.8
P/B	-22.5	23.0	·	5.5	2.0	1.3	·	3.8	2.9	3.2	·	3.4	2.6	2.8	·	3.1
P / Tangible Book	·	23.0	·	5.5	2.0	1.3	·	3.8	2.9	3.2	·	3.4	2.6	2.8	·	3.1
P / Cash Flow	·	-4.8	·	·	·	-2.0	·	·	·	-9.5	·	·	·	-10.6	·	·
EV / Revenue	4.4	2.3	·	0.5	-1.9	-2.5	·	·	·	·	·	·	·	·	·	·
Earnings Yield	-54.7%	-55.4%	·	-36.1%	-82.9%	-102.4%	·	-36.7%	-39.9%	-23.1%	·	-26.2%	-28.8%	-26.3%	·	-17.5%

Periodo più recente a sinistra · valori nulli mostrati come ·

Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni

16

Metrica	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Ricavi	$21M	$101M	$97M	$134M	$207M
Margine Operativo %	-741.3%	-144.1%	-156.3%	-103.2%	-18.0%
Utile netto	$-143M	$-119M	$-130M	$-133M	$-36M
EPS Diluito	$-1.39	$-1.23	$-1.56	$-1.62	$-0.45

Metrica	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Debito / Patrimonio Netto	0.3	0.1	·	·	·
Rapporto corrente	3.8	3.4	3.2	7.7	5.4
Quick Ratio	3.7	3.3	3.1	7.6	5.3

Metrica	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Flusso di cassa libero	$-184M	$-231M	$-187M	$-24M	$295M

Proprietari istituzionali (13F) 154 filer · $189.3M totale · Aggiornato al 30 Giugno 2026

17

Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.

Detentori 154

Valore detenuto $189.3M

Nuove posizioni 19

Posizioni chiuse 8

Attività istituzionale — Q2 2026 vs trimestre precedente

Nuove posizioni	Posizioni chiuse	Aumentato	Diminuito	Variazione netta delle azioni
19 (-10 vs trimestre precedente)	8 (-10 vs trimestre precedente)	59 (+15 vs trimestre precedente)	34 (-2 vs trimestre precedente)	+4.1M

Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.

Istituzione	Valore	Azioni	% di 13F tracciati	Tipo
TCG Crossover Management, LLC	$20.100.000	10.000.000	10,62%	Azioni
BlackRock, Inc.	$15.774.236	7.847.879	8,33%	Azioni
VANGUARD GROUP INC	$10.776.564	6.908.054	5,69%	Azioni
Nantahala Capital Management, LLC	$8.679.399	4.318.109	4,58%	Azioni
VANGUARD CAPITAL MANAGEMENT LLC	$8.058.773	4.009.340	4,26%	Azioni
Kynam Capital Management, LP	$7.655.073	3.808.494	4,04%	Azioni
Merck & Co., Inc.	$7.126.896	3.545.719	3,76%	Azioni
Balyasny Asset Management L.P.	$6.527.326	3.247.426	3,45%	Azioni
683 Capital Management, LLC	$6.432.000	3.200.000	3,40%	Azioni
D. E. Shaw & Co., Inc.	$5.949.566	2.959.983	3,14%	Azioni
ADAR1 Capital Management, LLC	$5.796.002	2.883.583	3,06%	Azioni
VANGUARD PORTFOLIO MANAGEMENT LLC	$5.669.191	2.820.493	2,99%	Azioni
GEODE CAPITAL MANAGEMENT, LLC	$4.934.077	2.454.271	2,61%	Azioni
Spruce Street Capital LP	$4.223.147	2.101.068	2,23%	Azioni
MILLENNIUM MANAGEMENT LLC	$3.997.558	1.988.835	2,11%	Azioni
Ikarian Capital, LLC	$3.985.038	1.982.606	2,10%	Azioni
STATE STREET CORP	$3.778.328	1.879.765	2,00%	Azioni
JACOBS LEVY EQUITY MANAGEMENT, INC	$3.549.517	1.765.929	1,87%	Azioni
MEDICI CAPITAL LLC	$3.321.565	1.652.520	1,75%	Azioni
Affinity Asset Advisors, LLC	$3.035.100	1.510.000	1,60%	Azioni
Eversept Partners, LP	$2.861.985	1.423.873	1,51%	Azioni
FMR LLC	$2.806.759	1.396.398	1,48%	Azioni
AQR CAPITAL MANAGEMENT LLC	$2.632.249	1.309.577	1,39%	Azioni
Euclidean Capital LLC	$2.628.795	1.307.858	1,39%	Azioni
MACKENZIE FINANCIAL CORP	$2.230.638	1.109.770	1,18%	Azioni
DEUTSCHE BANK AG\	$2.207.760	1.098.388	1,17%	Azioni
DEERFIELD MANAGEMENT COMPANY, L.P.	$2.120.936	1.055.192	1,12%	Azioni
TWO SIGMA INVESTMENTS, LP	$2.101.206	1.045.376	1,11%	Azioni
RENAISSANCE TECHNOLOGIES LLC	$1.879.684	935.166	0,99%	Azioni
DAFNA Capital Management LLC	$1.825.786	908.351	0,96%	Azioni
Elmind Capital, LP	$1.809.000	900.000	0,96%	Azioni
PANAGORA ASSET MANAGEMENT INC	$1.700.458	845.999	0,90%	Azioni
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	$1.645.850	818.831	0,87%	Azioni
NORTHERN TRUST CORP	$1.554.659	773.462	0,82%	Azioni
VANGUARD FIDUCIARY TRUST CO	$1.333.820	663.592	0,70%	Azioni
MARSHALL WACE, LLP	$1.203.105	598.559	0,64%	Azioni
BOOTHBAY FUND MANAGEMENT, LLC	$1.071.029	532.850	0,57%	Azioni
TWO SIGMA ADVISERS, LP	$1.016.808	651.800	0,54%	Azioni
Balyasny Asset Management L.P.	$1.012.839	503.900	0,53%	Opzione Call
New Leaf Venture Partners, L.L.C.	$1.005.124	339.569	0,53%	Azioni
GOLDMAN SACHS GROUP INC	$872.089	433.875	0,46%	Azioni
XTX Topco Ltd	$803.359	399.681	0,42%	Azioni
CITADEL ADVISORS LLC	$786.376	391.232	0,42%	Azioni
CANTOR FITZGERALD, L. P.	$593.939	295.492	0,31%	Azioni
UBS Group AG	$550.298	273.780	0,29%	Azioni
Invesco Ltd.	$516.849	257.139	0,27%	Azioni
Bank of New York Mellon Corp	$502.688	250.093	0,27%	Azioni
AMERIPRISE FINANCIAL INC	$451.305	224.530	0,24%	Azioni
NANO CAP NEW MILLENNIUM GROWTH FUND L P	$402.000	200.000	0,21%	Azioni
LMR Partners LLP	$402.000	200.000	0,21%	Azioni

Mostra tutti i 154 proprietari istituzionali →

Attivisti e proprietari del 5%+ 1 partecipazione

18

Investitori che hanno depositato SEC Schedule 13D — proprietà effettiva superiore al 5% con l'intento di influenzare l'emittente (partecipazioni attiviste, campagne per il consiglio di amministrazione, M&A). Ogni riga mostra lo stato più recente noto della posizione di quel depositante.

Depositante	Depositato	Partecipazione	Stato	Scopo	Deposito
OrbiMed Advisors LLC, OrbiMed Capital GP IV LLC ×10 depositi	16 Luglio 2020	·	Deposito iniziale	·	SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Insider aziendali 22 insider · 11 dirigenti · 12 direttori

19

Insider	Ruolo	Ultima attività	Azioni possedute	Vendite 12m	Netto 12m
Arnon Rosenthal	Chief Executive Officer	03 Settembre 2026 S	2.294.600	4	$-655.369
Neil Lindsay Berkley	CFO & Chief Business Officer	03 Settembre 2026 S	350.649	4	$-220.535
Marc Grasso	Chief Financial Officer	02 Giugno 2025 S	296.072	0	$0
Sara Kenkare-Mitra	President and Head of R&D	03 Dicembre 2025 S	501.652	1	$-46.689
Shehnaaz Suliman	President and COO	13 Dicembre 2021 M	102.598	0	$0
Grace Wong-Sarad	Principal Accounting Officer	04 Settembre 2026 S	106.015	12	$-99.033
Gary Romano	Chief Medical Officer	03 Marzo 2025 S	332.977	0	$0
Robert King	Chief Development Officer	01 Ottobre 2022 A	550.871	0	$0
Robert Paul	Chief Medical Officer	09 Agosto 2021 M	234.319	0	$0
Calvin Yu	Vice President, Finance	06 Luglio 2021 M	76.686	0	$0
Sabah Oney	Chief Business Officer	01 Ottobre 2020 A	573.918	0	$0
Elizabeth A. Garofalo	Direttore	17 Giugno 2026 A	118.650	0	$0
Paula Hammond	Direttore	17 Giugno 2026 A	103.609	0	$0
Kristine Yaffe	Direttore	17 Giugno 2026 A	124.109	0	$0
Mark Altmeyer	Direttore	17 Giugno 2026 A	98.650	0	$0
Richard H Scheller	Direttore	17 Giugno 2026 A	134.899	0	$0
Louis J Lavigne JR	Direttore	17 Giugno 2026 A	128.109	0	$0
Errol B Desouza	Direttore	17 Giugno 2026 A	98.650	0	$0
David M. Wehner	Direttore	12 Giugno 2024 A	115.330	0	$0
Terrance McGuire	Direttore	11 Settembre 2023 S	10.853.817	0	$0
Tillman U. Gerngross	Direttore	14 Giugno 2023 A	2.644.319	0	$0
GORDON CARL L	Direttore	10 Maggio 2019 A	203.200	0	$0

Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato

Proprietà ETF Posseduti da 18 ETF

20

Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.

Fondo	Peso	Unità	Aggiornato al	Fonte
QQQS · Invesco Exchange-Traded Fund Trust …	0,42%	53.037 SH	01 Ottobre 2026	Giornaliero
UAE · iShares Trust	0,41%	3.282.337 SH	11 Settembre 2026	Giornaliero
IBRN · iShares Trust	0,18%	6.349 SH	11 Settembre 2026	Giornaliero
IWC · iShares Trust	0,05%	336.837 SH	11 Settembre 2026	Giornaliero
EEMS · iShares, Inc.	0,02%	212.007 SH	11 Settembre 2026	Giornaliero
IWO · iShares Trust	0,01%	820.921 SH	11 Settembre 2026	Giornaliero
PRFZ · Invesco Exchange-Traded Fund Trust	0,01%	155.185 SH	01 Ottobre 2026	Giornaliero
VTWO · VANGUARD SCOTTSDALE FUNDS	0,01%	563.396 SH	19 Agosto 2026	Giornaliero
VTWG · VANGUARD SCOTTSDALE FUNDS	0,01%	94.277 SH	19 Agosto 2026	Giornaliero
IWM · iShares Trust	0,01%	2.501.663 SH	11 Settembre 2026	Giornaliero
DFSU · Dimensional ETF Trust	0,00%	3.867 NS	31 Luglio 2026	N-PORT
IWV · iShares Trust	0,00%	16.616 SH	03 Settembre 2026	Giornaliero
VXF · VANGUARD INDEX FUNDS	0,00%	1.071.545 SH	19 Agosto 2026	Giornaliero
VTI · VANGUARD INDEX FUNDS	0,00%	2.837.922 SH	19 Agosto 2026	Giornaliero
VTWV · VANGUARD SCOTTSDALE FUNDS	0,00%	9.493 SH	19 Agosto 2026	Giornaliero
VTHR · VANGUARD SCOTTSDALE FUNDS	0,00%	5.223 SH	19 Agosto 2026	Giornaliero
VHT · VANGUARD WORLD FUND	0,00%	230.061 SH	19 Agosto 2026	Giornaliero
IWN · iShares Trust	·	160.282 SH	11 Settembre 2026	Giornaliero

ALEC Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo

21

rating · 14 analisti COMPRA

Target mediano $2.00 +10,5%

3 21,4% Acquisto forte

5 35,7% Compra

4 28,6% Mantieni

2 14,3% Vendi

0 0,0% Vendita forte

Target Price a 12 Mesi

5 analisti · 2026-10-02

Target medio $3.10 +71,3%

Ora Prezzo attuale $1.81

Basso$1.00 Media$3.10 Alto$6.00

Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore

22

Base FY, prezzi alla chiusura dell'ultimo anno fiscale di ciascuna società.

Ticker	Capitalizzazione di Mercato	P/E	Rev YoY	Margine Netto	ROE	Margine lordo
ALEC	$172M	-1.1	-79.1%	-679.2%	-280.7%	·
KROS	$398M	8.9	·	35.7%	17.2%	·
RNAC	$188M	-1.4	-92.8%	-4658.6%	202.4%	·
TRDA	$394M	-3.0	-87.9%	-565.5%	-41.9%	·
WHWK	$114M	-7.3	-72.5%	-288.3%	-13.4%	·
ELDN	$114M	-2.9	·	·	-69.4%	·
NKTX	$131M	-1.3	·	·	-31.1%	·
CUE	$29M	-1.1	195.8%	-96.9%	-119.3%	·
CHRS	$172M	1.0	59.8%	398.4%	185.8%	·
CNTN	$112M	-2.7	·	·	-18.0%	·

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ALEC Alector, Inc. - Common Stock