PLRX Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane

03

Prezzo $1.03

Capitalizzazione di Mercato (MRQ) $64M

P/E -0.4

EPS $-2.43

Ricavi $0

ROE -74.4%

Intervallo 52 sett. $1–$2

PLRX Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione

04

intervallo

barre

La granularità delle barre si adatta al periodo selezionato — passa il mouse sul grafico per vedere apertura/massimo/minimo/chiusura di una barra.

Informazioni su Pliant Therapeutics, Inc. - Common Stock Panoramica della società da Wikipedia

05 · wikidata

Wikidata ↗

settoreHealthcare industriaPharmaceuticals dipendenti49 paeseUS

Performance decennale Andamento di ricavi, utile netto, margini e EPS

06

Ricavi$0

2019-12-31 → 2025-12-31

EPS$-2.43

2019-12-31 → 2025-12-31

Flusso di cassa libero$-129M

2020-12-31 → 2025-12-31

Margine netto·

2020-12-31 → 2023-12-31

Valutazione e Rapporti 07–12

Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?

Metrica	PLRX	media 5 anni	Mediana dei peer	Verdetto
P/E	-0.4media 5 anni ≈-4.5	≈-4.5	·	·
P/B (MRQ)	0.4media 5 anni ≈2.1	≈2.1	3.9	Sottovalutato
Prezzo / FCF (TTM)	-0.9media 5 anni ≈-6.2	≈-6.2	·	·
Prezzo / Flusso di cassa (TTM)	-0.9media 5 anni ≈-6.3	≈-6.3	·	·
Price / Tangible Book (Prezzo / Valore contabile tangibile)	0.4media 5 anni ≈2.1	≈2.1	·	·

La mediana dei peer viene calcolata su base standardizzata per metrica e potrebbe non corrispondere sempre alla base TTM/MRQ mostrata per questo titolo.

Redditività Margini lordi, operativi e netti; ROE, ROA, ROIC

Metrica	Tendenza 5 anni	PLRX	media 5 anni	Mediana dei peer	Verdetto
ROA		-48.0%media 5 anni ≈-43.7%	≈-43.7%	-53.7%	In linea
ROE		-74.4%media 5 anni ≈-52.5%	≈-52.5%	-120.8%	Di prim'ordine

Salute finanziaria Debito, liquidità, solvibilità — solidità del bilancio

Metrica	Tendenza 5 anni	PLRX	media 5 anni	Mediana dei peer	Verdetto
Rapporto corrente (MRQ)		9.9media 5 anni ≈13.7	≈13.7	4.3	Liquidità elevata
Quick Ratio		11.7media 5 anni ≈13.4	≈13.4	4.1	Liquidità elevata

Crescita Crescita di ricavi, EPS e utile netto: YoY, CAGR 3Y, CAGR 5Y

Metrica	Tendenza 5 anni	PLRX	media 5 anni	Mediana dei peer	Verdetto
Revenue YoY (Ricavi YoY)		-83.7%media 5 anni ≈-45.9%	≈-45.9%	·	·
Revenue CAGR 3Y (CAGR Ricavi 3Y)		-66.4%	·	·	·

Metriche per Azione EPS, valore contabile per azione, flusso di cassa per azione, dividendo per azione

Metrica	PLRX	media 5 anni	Mediana dei peer	Verdetto
EPS (Diluted) (EPS (Diluito))	$-2.43media 5 anni ≈$-2.86	≈$-2.86	·	·
Revenue / Share (Ricavi / Azione)	$0.00media 5 anni ≈$0.06	≈$0.06	·	·
Cash Flow / Share (Flusso di cassa / Azione)	$-2.09media 5 anni ≈$-2.22	≈$-2.22	·	·
Cash / Share (Liquidità / Azione)	$0.74media 5 anni ≈$0.91	≈$0.91	·	·

Efficienza del Capitale Rotazione delle attività, rotazione delle scorte, rotazione dei crediti

Metrica	Tendenza 5 anni	PLRX	media 5 anni	Mediana dei peer	Verdetto
Asset Turnover (Rotazione delle attività)		0.0media 5 anni ≈0.0	≈0.0	0.0	Debole
Revenue / Employee (Ricavi / Dipendente)		≈$0.00	·	·	·

valore · ≈ media 5 anni · mediana del settore · giudizio rispetto alla mediana

Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili

14

Sorpresa media 0.86%

Prossimo report Nov 04, 2026

Periodo	Rapporto	EPS Actual	EPS Stimato	Sorpresa
30 Giugno 2026	Ago 5, 2026	$-0.36	$-0.35	-3.2%
31 Marzo 2026	Mag 6, 2026	$-0.32	$-0.36	12.0%
31 Dicembre 2025		$-0.38	$-0.39	1.5%
30 Settembre 2025		$-0.43	$-0.53	19.5%
30 Giugno 2025		$-0.71	$-0.71	-0.10%
31 Marzo 2025		$-0.92	$-0.74	-24.5%

Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario

15

Conto Economico 15

Metrica	2025	2024	2023	2022	2021	2020	2019
Revenue	$0	$0	$2M	$10M	$8M	$42M	$57M
R&D Expense	$109M	$169M	$128M	$97M	$78M	$66M	$47M
SG&A Expense	$47M	$59M	$58M	$40M	$28M	$17M	$11M
Operating Expenses	$156M	$228M	$186M	$137M	$105M	$83M	$58M
Operating Income	$-156M	$-228M	$-184M	$-127M	$-98M	$-42M	$-1M
Interest Expense	·	·	$1M	$791.0K	$0	·	·
Interest Income	·	·	·	·	·	$478.0K	$816.0K
Other Non-op	·	·	·	·	·	$-366.0K	$-216.0K
Income Tax	$0	$0	$0	$0	$0	$0	$0
Net Income	$-149M	$-210M	$-161M	$-123M	$-97M	$-42M	$-631.0K
EPS (Basic)	$-2.43	$-3.47	$-2.75	$-2.94	$-2.71	$-1.95	$-4.22
EPS (Diluted)	$-2.43	$-3.47	$-2.75	$-2.94	$-2.71	$-1.95	$-4.22
Shares (Basic)	61,366,887	60,538,639	58,719,083	42,015,908	35,846,421	21,344,236	1,623,358
Shares (Diluted)	61,366,887	60,538,639	58,719,083	42,015,908	35,846,421	21,344,236	1,623,358
EBITDA	$-156M	$-228M	$-184M	$-127M	·	$-42M	·

Stato Patrimoniale 23

Metrica	2025	2024	2023	2022	2021	2020	2019
Cash & Equivalents	$45M	$71M	$63M	$34M	$52M	$51M	$86M
Short-term Investments	$145M	$285M	$431M	$298M	$149M	$226M	$17M
Receivables	·	·	$0	$2M	$2M	$9M	$7M
Prepaid Expense	$4M	$7M	$11M	$7M	$7M	$4M	$2M
Current Assets	$196M	$362M	$506M	$340M	$209M	$291M	$112M
PP&E (Net)	$3M	$6M	$4M	$4M	$5M	$4M	$4M
PP&E (Gross)	$14M	$16M	$12M	$11M	$10M	$8M	$6M
Accum. Depreciation	$11M	$11M	$9M	$7M	$5M	$3M	$2M
Other Non-current Assets	$392.0K	$435.0K	$392.0K	$394.0K	$838.0K	$451.0K	$3M
Total Assets	$225M	$397M	$512M	$351M	$221M	$296M	$119M
Accounts Payable	$480.0K	$6M	$5M	$2M	$3M	$2M	$1M
Accrued Liabilities	$10M	$12M	$10M	$9M	$12M	$10M	$7M
Current Liabilities	$16M	$33M	$29M	$24M	$17M	$12M	$8M
Capital Leases	$28M	$29M	$0	$3M	$5M	$0	·
Other Non-current Liabilities	·	·	·	·	$0	$866.0K	$912.0K
Total Liabilities	$44M	$93M	$39M	$37M	$22M	$12M	$9M
Long-term Debt	$0	$30M	$10M	$10M	$0	·	·
Common Stock	$6.0K	$6.0K	$6.0K	$5.0K	$3.0K	$3.0K	$1.0K
Retained Earnings	$-859M	$-710M	$-500M	$-338M	$-215M	$-118M	$-76M
AOCI	$-15.0K	$321.0K	$345.0K	$-2M	$-201.0K	$-32.0K	$-1.0K
Stockholders' Equity	$181M	$304M	$474M	$313M	$199M	$283M	$-76M
Liabilities + Equity	$225M	$397M	$512M	$351M	$221M	$296M	$119M
Shares Outstanding	61,449,290	60,860,838	59,921,002	48,941,254	36,083,301	35,552,795	1,846,024

Flusso di cassa 8

Metrica	2025	2024	2023	2022	2021	2020	2019
Stock-based Comp	$26M	$38M	$44M	$23M	$10M	$4M	$2M
Operating Cash Flow	$-128M	$-156M	$-116M	$-95M	$-75M	$-37M	$-3M
CapEx	$374.0K	$4M	$921.0K	$2M	$2M	$2M	$964.0K
Investing Cash Flow	$134M	$140M	$-127M	$-150M	$74M	$-211M	$-18M
Financing Cash Flow	$-32M	$23M	$274M	$227M	$3M	$213M	$46M
Net Change in Cash	$-26M	$8M	$31M	$-18M	$783.0K	$-35M	$25M
Taxes Paid	$0	$0	·	·	·	·	·
Free Cash Flow	$-129M	$-159M	$-117M	$-96M	·	$-39M	·

Redditività 5

Metrica	2025	2024	2023	2022	2021	2020	2019
Operating Margin	·	·	-11654.8%	-1313.4%	·	-99.6%	·
Net Margin	·	·	-10211.1%	-1273.3%	·	-99.3%	·
EBITDA Margin	·	·	-11654.8%	-1313.4%	·	-99.6%	·
ROA	-48.0%	-46.3%	-37.4%	-43.1%	·	-20.0%	·
ROE	-74.4%	-64.7%	-33.0%	-37.9%	·	-14.2%	·

Liquidità e Solvibilità 3

Metrica	2025	2024	2023	2022	2021	2020	2019
Current Ratio	12.0	10.9	17.7	14.2	·	25.1	·
Quick Ratio	11.7	10.7	17.3	13.9	·	24.7	·
Interest Coverage	·	·	-145.3	·	·	·	·

Efficienza 2

Metrica	Tendenza	2025	2024	2023	2022	2021	2020	2019
Asset Turnover		0.0	0.0	0.0	0.0	·	0.2	·
Receivables Turnover		·	·	1.6	4.9	·	5.1	·

Per Azione 7

Metrica	2025	2024	2023	2022	2021	2020	2019
Book Value / Share	$2.95	$5.00	$7.90	$6.40	·	$7.96	·
Revenue / Share	$0.00	$0.00	$0.03	$0.23	·	$1.96	·
Cash Flow / Share	$-2.09	$-2.57	$-1.98	$-2.25	·	$-1.75	·
Cash / Share	$0.74	$1.17	$1.06	$0.69	·	$1.43	·
Dividend / Share	$0.00	$0.00	$0.00	$0.00	·	$0.00	·
Dividend Paid / Share	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	·
EPS (TTM)	$-2.43	$-3.47	$-2.75	$-2.94	$-2.71	$-1.95	·

Tassi di Crescita 2

Metrica	Tendenza	2025	2024	2023	2022	2021	2020	2019
Revenue YoY		·	·	-83.7%	27.9%	-81.9%	·	·
Revenue CAGR 3Y		·	·	-66.4%	·	·	·	·

Valutazione (TTM) 10

Metrica	2025	2024	2023	2022	2021	2020	2019
Revenue TTM	$0	$0	$2M	$10M	$8M	$42M	·
Net Income TTM	$-149M	$-210M	$-161M	$-123M	$-97M	$-42M	·
Market Cap	$75M	$802M	$1.09B	$946M	·	$808M	·
P/E	-0.5	-3.8	-6.6	-6.6	-5.0	-11.7	·
P/S	·	·	686.8	97.7	·	19.3	·
P/B	0.4	2.6	2.3	3.0	·	2.9	·
P / Tangible Book	0.4	2.6	2.3	3.0	·	2.9	·
P / Cash Flow	-0.6	-5.2	-9.3	-10.0	·	-21.7	·
P / FCF	-0.6	-5.0	-9.3	-9.8	·	-20.8	·
Earnings Yield	-199.2%	-26.4%	-15.2%	-15.2%	-20.1%	-8.6%	·

Conto Economico 13

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q3 2022	Q2 2022
Revenue	·	·	·	·	·	·	$0	$0	$0	$0	$0	$0	$248.0K	$1M	$1M	$5M
R&D Expense	$17M	$14M	$16M	$18M	$32M	$43M	$39M	$48M	$46M	$37M	$33M	$32M	$33M	$29M	$25M	$26M
SG&A Expense	$7M	$8M	$8M	$10M	$13M	$15M	$15M	$14M	$15M	$15M	$14M	$15M	$15M	$14M	$9M	$8M
Operating Expenses	$24M	$22M	$24M	$28M	$46M	$59M	$53M	$62M	$61M	$52M	$47M	$48M	$48M	$43M	$33M	$35M
Operating Income	$-24M	$-22M	$-24M	$-28M	$-46M	$-59M	$-53M	$-62M	$-61M	$-52M	$-47M	$-48M	$-47M	$-42M	$-32M	$-30M
Interest Expense	·	·	·	·	·	·	·	·	·	$445.0K	·	$317.0K	$319.0K	$311.0K	$301.0K	$173.0K
Income Tax	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
Net Income	$-22M	$-20M	$-24M	$-26M	$-43M	$-56M	$-50M	$-58M	$-56M	$-47M	$-41M	$-41M	$-41M	$-38M	$-31M	$-30M
EPS (Basic)	$-0.36	$-0.32	$-0.37	$-0.43	$-0.71	$-0.92	$-0.82	$-0.95	$-0.92	$-0.78	$-0.68	$-0.70	$-0.70	$-0.67	$-0.65	$-0.82
EPS (Diluted)	$-0.36	$-0.32	$-0.37	$-0.43	$-0.71	$-0.92	$-0.82	$-0.95	$-0.92	$-0.78	$-0.68	$-0.70	$-0.70	$-0.67	$-0.65	$-0.82
Shares (Basic)	61,919,233	61,803,467	·	61,406,475	61,386,183	61,222,676	·	60,730,935	60,382,796	60,180,921	·	59,688,451	59,172,869	56,057,603	46,799,058	36,173,135
Shares (Diluted)	61,919,233	61,803,467	·	61,406,475	61,386,183	61,222,676	·	60,730,935	60,382,796	60,180,921	·	59,688,451	59,172,869	56,057,603	46,799,058	36,173,135
EBITDA	$-24M	$-22M	·	$-28M	$-46M	$-59M	·	$-62M	$-61M	$-52M	·	$-48M	$-47M	$-42M	$-32M	$-30M

Stato Patrimoniale 22

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q3 2022	Q2 2022
Cash & Equivalents	$25M	$22M	$45M	$94M	$87M	$92M	$71M	$80M	$80M	$114M	$63M	$58M	$55M	$103M	$45M	$25M
Short-term Investments	$133M	$149M	$145M	$148M	$176M	$214M	$285M	$325M	$356M	$368M	$431M	$466M	$500M	$475M	$316M	$139M
Receivables	·	·	·	·	·	·	·	·	·	·	·	$0	$2M	$3M	$1M	$5M
Prepaid Expense	$4M	$3M	$4M	$4M	$5M	$6M	$7M	$6M	$11M	$8M	$11M	$11M	$9M	$8M	$4M	$5M
Current Assets	$163M	$175M	$196M	$246M	$267M	$311M	$362M	$410M	$448M	$490M	$506M	$534M	$566M	$588M	$366M	$174M
PP&E (Net)	$2M	$3M	$3M	$4M	$5M	$5M	$6M	$6M	$5M	$6M	$4M	$4M	$4M	$4M	$5M	$5M
PP&E (Gross)	$13M	$13M	$14M	$16M	$17M	$16M	$16M	$16M	$15M	$15M	$12M	$12M	$12M	$11M	$11M	$10M
Accum. Depreciation	$11M	$10M	$11M	$12M	$12M	$11M	$11M	$10M	$10M	$9M	$9M	$8M	$8M	$7M	$6M	$6M
Other Non-current Assets	$554.0K	$389.0K	$392.0K	$392.0K	$391.0K	$427.0K	$435.0K	$427.0K	$437.0K	$392.0K	$392.0K	$392.0K	$672.0K	$644.0K	$397.0K	$913.0K
Total Assets	$190M	$203M	$225M	$277M	$300M	$345M	$397M	$446M	$484M	$522M	$512M	$540M	$575M	$598M	$377M	$185M
Accounts Payable	$2M	$362.0K	$480.0K	$485.0K	$1M	$6M	$6M	$7M	$3M	$7M	$5M	$3M	$2M	$1M	$3M	$3M
Accrued Liabilities	$4M	$4M	$10M	$8M	$7M	$7M	$12M	$10M	$8M	$6M	$10M	$8M	$7M	·	$20M	$17M
Current Liabilities	$16M	$10M	$16M	$18M	$21M	$28M	$33M	$40M	$31M	$30M	$29M	$27M	$30M	$23M	$26M	$23M
Capital Leases	$26M	$27M	$28M	$28M	$29M	$29M	$29M	$30M	$30M	$24M	$0	$0	$2M	$3M	$4M	$4M
Total Liabilities	$43M	$37M	$44M	$76M	$80M	$88M	$93M	$100M	$91M	$84M	$39M	$37M	$42M	$36M	$40M	$37M
Long-term Debt	$0	$0	$0	$30M	$30M	$30M	$30M	$30M	$30M	$30M	$10M	$10M	$10M	$10M	$10M	$10M
Common Stock	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$6.0K	$5.0K	$3.0K
Retained Earnings	$-902M	$-879M	$-859M	$-836M	$-810M	$-766M	$-710M	$-660M	$-603M	$-547M	$-500M	$-459M	$-417M	$-376M	$-303M	$-273M
AOCI	$-397.0K	$-341.0K	$-15.0K	$34.0K	$-1.0K	$159.0K	$321.0K	$848.0K	$-617.0K	$-489.0K	$345.0K	$-2M	$-2M	$-1M	$-2M	$-1M
Stockholders' Equity	$147M	$165M	$181M	$200M	$220M	$257M	$304M	$346M	$393M	$437M	$474M	$503M	$533M	$562M	$337M	$148M
Liabilities + Equity	$190M	$203M	$225M	$277M	$300M	$345M	$397M	$446M	$484M	$522M	$512M	$540M	$575M	$598M	$377M	$185M
Shares Outstanding	61,920,154	61,914,569	61,449,290	61,449,290	61,386,183	61,386,183	60,860,838	60,849,503	60,425,144	60,318,542	59,921,002	59,890,980	59,222,685	58,978,902	48,749,842	36,182,297

Flusso di cassa 7

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q3 2022	Q2 2022
Stock-based Comp	$4M	$4M	$5M	$6M	$6M	$9M	$8M	$9M	$11M	$10M	$9M	$10M	$13M	$12M	$5M	$3M
Operating Cash Flow	$-13M	$-19M	$-18M	$-21M	$-41M	$-49M	$-48M	$-32M	$-45M	$-30M	$-25M	$-36M	$-25M	$-30M	$-18M	$-24M
CapEx	$0	$0	$0	$0	$112.0K	$262.0K	$209.0K	$896.0K	$1M	$1M	$61.0K	$94.0K	$603.0K	$163.0K	$696.0K	$254.0K
Investing Cash Flow	$15M	$-4M	$2M	$28M	$35M	$69M	$39M	$31M	$11M	$60M	$32M	$38M	$-23M	$-174M	$-178M	$6M
Financing Cash Flow	$0	$74.0K	$-32M	$72.0K	$0	$498.0K	$102.0K	$543.0K	$684.0K	$22M	$219.0K	$699.0K	$161.0K	$273M	$216M	$10M
Net Change in Cash	$3M	$-23M	$-48M	$7M	$-5M	$21M	$-8M	$-770.0K	$-34M	$51M	$7M	$3M	$-48M	$69M	$20M	$-7M
Free Cash Flow	·	$-19M	·	·	·	$-49M	·	·	·	$-32M	·	·	·	$-30M	·	·

Redditività 5

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q3 2022	Q2 2022
Operating Margin	·	·	·	·	·	·	·	·	·	·	·	·	-19083.9%	-3160.3%	-2155.7%	-594.1%
Net Margin	·	·	·	·	·	·	·	·	·	·	·	·	-16609.7%	-2818.9%	-2065.8%	-592.2%
EBITDA Margin	·	·	·	·	·	·	·	·	·	·	·	·	-19083.9%	-3160.3%	-2155.7%	-594.1%
ROA	-9.1%	-7.3%	·	-7.3%	-11.1%	-13.0%	·	-11.7%	-10.5%	-8.4%	·	-9.0%	-10.8%	-9.4%	-10.0%	-13.4%
ROE	-12.2%	-9.5%	·	-9.6%	-14.1%	-16.2%	·	-13.6%	-12.1%	-9.4%	·	-9.9%	-12.1%	-10.2%	-11.0%	-15.1%

Liquidità e Solvibilità 3

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q3 2022	Q2 2022
Current Ratio	9.9	16.9	·	13.9	13.0	11.0	·	10.3	14.5	16.1	·	19.5	19.2	25.4	14.0	7.7
Quick Ratio	9.6	16.5	·	13.7	12.8	10.8	·	10.1	14.1	15.9	·	19.1	18.9	25.1	13.8	7.5
Interest Coverage	·	·	·	·	·	·	·	·	·	-117.7	·	-150.4	-148.4	-135.4	·	·

Efficienza 2

Metrica	Tendenza	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q3 2022	Q2 2022
Asset Turnover		·	·	·	·	·	·	·	0.0	0.0	0.0	·	0.0	0.0	0.0	0.0	0.0
Receivables Turnover		·	·	·	·	·	·	·	·	·	·	·	0.0	0.1	0.6	1.0	1.5

Per Azione 7

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q3 2022	Q2 2022
Book Value / Share	$2.37	$2.67	·	$3.26	$3.59	$4.19	·	$5.68	$6.50	$7.25	·	$8.40	$9.00	$9.53	$6.91	$4.08
Revenue / Share	·	·	·	·	·	·	·	$0.00	$0.00	$0.00	·	$0.00	$0.00	$0.02	$0.03	$0.14
Cash Flow / Share	·	$-0.31	·	·	·	$-0.80	·	·	·	$-0.50	·	·	·	$-0.54	·	·
Cash / Share	$0.40	$0.36	·	$1.53	$1.41	$1.50	·	$1.31	$1.33	$1.89	·	$0.96	$0.93	$1.74	$0.92	$0.69
Dividend / Share	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	·	$0.00	$0.00	$0.00	·	$0.00	$0.00	$0.00	·	$0.00
Dividend Paid / Share	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	·	$0.00	$0.00	$0.00	·	$0.00	$0.00	$0.00	·	$0.00
EPS (TTM)	$-1.48	$-1.83	·	$-2.88	$-3.40	$-3.61	·	$-3.33	$-3.08	$-2.86	·	$-2.76	$-2.71	$-2.83	$-2.93	$-3.03

Valutazione (TTM) 9

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q3 2022	Q2 2022
Revenue TTM	$0	$0	·	$0	$0	$0	·	$0	$0	$248.0K	·	$4M	$5M	$10M	$10M	$10M
Net Income TTM	$-92M	$-113M	·	$-175M	$-207M	$-220M	·	$-202M	$-185M	$-171M	·	$-155M	$-144M	$-133M	$-113M	$-109M
Market Cap	$71M	$78M	·	$91M	$71M	$83M	·	$682M	$650M	$899M	·	$1.04B	$1.07B	$1.57B	$1.02B	$290M
P/E	-0.8	-0.7	·	-0.5	-0.3	-0.4	·	-3.4	-3.5	-5.2	·	-6.3	-6.7	-9.4	-7.1	-2.6
P/S	·	·	·	·	·	·	·	·	·	3624.0	·	293.0	213.5	160.6	104.8	29.4
P/B	0.5	0.5	·	0.5	0.3	0.3	·	2.0	1.7	2.1	·	2.1	2.0	2.8	3.0	2.0
P / Tangible Book	0.5	0.5	·	0.5	0.3	0.3	·	2.0	1.7	2.1	·	2.1	2.0	2.8	3.0	2.0
P / Cash Flow	·	-4.1	·	·	·	-1.7	·	·	·	-29.7	·	·	·	-51.8	·	·
Earnings Yield	-129.8%	-145.2%	·	-194.6%	-293.1%	-267.4%	·	-29.7%	-28.6%	-19.2%	·	-15.9%	-15.0%	-10.6%	-14.0%	-37.8%

Periodo più recente a sinistra · valori nulli mostrati come ·

Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni

16

Metrica	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Ricavi	$0	$0	$2M	$10M	$8M
Margine Operativo %	·	·	-11654.8%	-1313.4%	·
Utile netto	$-149M	$-210M	$-161M	$-123M	$-97M
EPS Diluito	$-2.43	$-3.47	$-2.75	$-2.94	$-2.71

Metrica	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Rapporto corrente	12.0	10.9	17.7	14.2	·
Quick Ratio	11.7	10.7	17.3	13.9	·

Metrica	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Flusso di cassa libero	$-129M	$-159M	$-117M	$-96M	·

Proprietari istituzionali (13F) 99 filer · $56.9M totale · Aggiornato al 30 Giugno 2026

17

Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.

Detentori 99

Valore detenuto $56.9M

Nuove posizioni 12

Posizioni chiuse 12

Attività istituzionale — Q2 2026 vs trimestre precedente

Nuove posizioni	Posizioni chiuse	Aumentato	Diminuito	Variazione netta delle azioni
12 (-2 vs trimestre precedente)	12 (-1 vs trimestre precedente)	18 (-8 vs trimestre precedente)	27 (0 vs trimestre precedente)	-1.3M

Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.

Istituzione	Valore	Azioni	% di 13F tracciati	Tipo
TANG CAPITAL MANAGEMENT LLC	$7.001.038	6.141.261	12,30%	Azioni
ADAR1 Capital Management, LLC	$6.281.085	5.509.724	11,04%	Azioni
VANGUARD GROUP INC	$3.438.255	2.818.241	6,04%	Azioni
VANGUARD CAPITAL MANAGEMENT LLC	$2.782.000	2.440.351	4,89%	Azioni
TWO SIGMA INVESTMENTS, LP	$2.579.628	2.262.832	4,53%	Azioni
CITADEL ADVISORS LLC	$2.442.138	2.142.226	4,29%	Azioni
RENAISSANCE TECHNOLOGIES LLC	$2.336.856	2.049.874	4,11%	Azioni
Monaco Asset Management SAM	$2.210.172	1.938.747	3,88%	Azioni
Lynx1 Capital Management LP	$2.049.800	1.798.070	3,60%	Azioni
BML Capital Management, LLC	$1.762.596	1.546.137	3,10%	Azioni
Prosight Management, LP	$1.562.066	1.370.233	2,74%	Azioni
TWO SIGMA ADVISERS, LP	$1.519.632	1.245.600	2,67%	Azioni
Peapod Lane Capital LLC	$1.492.275	1.309.013	2,62%	Azioni
Woodline Partners LP	$1.478.049	1.296.534	2,60%	Azioni
BlackRock, Inc.	$1.312.384	1.151.214	2,31%	Azioni
Ikarian Capital, LLC	$1.140.000	1.000.000	2,00%	Azioni
Eversept Partners, LP	$1.016.224	891.425	1,79%	Azioni
MARSHALL WACE, LLP	$952.041	835.124	1,67%	Azioni
Redmile Group, LLC	$880.224	772.126	1,55%	Azioni
JPMORGAN CHASE & CO	$783.894	681.647	1,38%	Azioni
JACOBS LEVY EQUITY MANAGEMENT, INC	$733.157	643.120	1,29%	Azioni
GEODE CAPITAL MANAGEMENT, LLC	$659.954	578.577	1,16%	Azioni
UBS Group AG	$651.806	571.760	1,15%	Azioni
MILLENNIUM MANAGEMENT LLC	$637.770	559.447	1,12%	Azioni
BRIDGEWAY CAPITAL MANAGEMENT, LLC	$631.138	553.630	1,11%	Azioni
Connor, Clark & Lunn Investment Management Ltd.	$611.132	536.081	1,07%	Azioni
DAFNA Capital Management LLC	$555.180	487.000	0,98%	Azioni
XTX Topco Ltd	$502.562	440.844	0,88%	Azioni
Laurion Capital Management LP	$470.587	412.796	0,83%	Azioni
TORNO CAPITAL, LLC	$400.647	351.445	0,70%	Azioni
VANGUARD FIDUCIARY TRUST CO	$389.596	341.751	0,68%	Azioni
BOOTHBAY FUND MANAGEMENT, LLC	$345.420	303.000	0,61%	Azioni
MORGAN STANLEY	$340.833	298.976	0,60%	Azioni
SEI INVESTMENTS CO	$338.909	297.291	0,60%	Azioni
Verdad Advisers, LP	$320.731	281.343	0,56%	Azioni
ArrowMark Colorado Holdings LLC	$320.555	281.189	0,56%	Azioni
NANO CAP NEW MILLENNIUM GROWTH FUND L P	$313.500	275.000	0,55%	Azioni
STATE STREET CORP	$288.897	253.418	0,51%	Azioni
Stonepine Capital Management, LLC	$262.813	230.538	0,46%	Azioni
Rangeley Capital, LLC	$256.500	225.000	0,45%	Azioni
GOLDMAN SACHS GROUP INC	$237.787	208.585	0,42%	Azioni
Congress Wealth Management LLC / DE /	$231.907	199.920	0,41%	Azioni
Marquette Asset Management, LLC	$198.930	174.500	0,35%	Azioni
HighMark Wealth Management LLC	$189.495	166.224	0,33%	Azioni
VANGUARD PORTFOLIO MANAGEMENT LLC	$175.232	153.712	0,31%	Azioni
JANE STREET GROUP, LLC	$148.144	129.951	0,26%	Azioni
NORTHERN TRUST CORP	$142.568	125.060	0,25%	Azioni
ALGERT GLOBAL LLC	$140.678	123.402	0,25%	Azioni
OSAIC HOLDINGS, INC.	$131.013	114.924	0,23%	Azioni
Invesco Ltd.	$119.333	104.678	0,21%	Azioni

Mostra tutti i 99 proprietari istituzionali →

Attivisti e proprietari del 5%+ 1 partecipazione

18

Investitori che hanno depositato SEC Schedule 13D — proprietà effettiva superiore al 5% con l'intento di influenzare l'emittente (partecipazioni attiviste, campagne per il consiglio di amministrazione, M&A). Ogni riga mostra lo stato più recente noto della posizione di quel depositante.

Depositante	Depositato	Partecipazione	Stato	Scopo	Deposito
TANG CAPITAL MANAGEMENT, LLC, KEVIN TANG, TANG CAPITAL PARTNERS, LP, TANG CAPITAL PARTNERS INTERNATIONAL, LP, TANG CAPITAL PARTNERS III, INC, TANG CAPITAL PARTNERS IV, INC, CONCENTRA BIOSCIENCES, LLC	10 Marzo 2025	9,60%	Deposito iniziale	Investimento passivo	SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Insider aziendali 23 insider · 9 dirigenti · 14 direttori

19

Insider	Ruolo	Ultima attività	Azioni possedute	Vendite 12m	Netto 12m
Bernard Coulie	President and CEO	17 Aprile 2026 A	505.601	1	$-114.400
Keith Lamont Cummings	Chief Financial Officer	17 Aprile 2026 A	297.214	1	$-30.723
Minnie Kuo	Chief Operating Officer	17 Aprile 2026 A	37.806	1	$-8.854
David Raben	Chief Medical Officer	01 Ottobre 2026 A	·	0	$0
Lily Cheung	Chief Human Resource Officer	17 Aprile 2026 A	44.847	1	$-9.644
Mike Ouimette	General Counsel & Corp. Sec'y	23 Gennaio 2025 A	105.544	0	$0
Hans Hull	Chief Business Officer	23 Gennaio 2025 A	251.708	0	$0
Eric Lefebvre	Chief Medical Officer	23 Gennaio 2025 A	240.224	0	$0
Barbara Howes	Chief Human Resource Officer	23 Gennaio 2021 A	24.799	0	$0
Flavia Borellini	Direttore	09 Luglio 2026 A	·	0	$0
Robert Iannone	Direttore	09 Luglio 2026 A	·	0	$0
Steve E. Krognes	Direttore	11 Giugno 2026 A	·	0	$0
Darren S Cline	Direttore	11 Giugno 2026 A	·	0	$0
John T Curnutte	Direttore	11 Giugno 2026 A	·	0	$0
Thomas A Mccourt	Direttore	11 Giugno 2026 A	·	0	$0
Hoyoung Huh	Direttore	11 Giugno 2026 A	239.619	0	$0
Gayle A Crowell	Direttore	11 Giugno 2026 A	·	0	$0
Katharine Knobil	Direttore	05 Giugno 2025 A	·	0	$0
Suzanne Louise Bruhn	Direttore	05 Giugno 2025 A	·	0	$0
David E I Pyott	Direttore	05 Giugno 2025 A	·	0	$0
Smital Shah	Direttore	13 Giugno 2024 A	·	0	$0
Neil Exter	Direttore	16 Giugno 2022 A	0	0	$0
Charles J Homcy	·	29 Giugno 2021 A	·	0	$0

Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato

Proprietà ETF Posseduti da 5 ETF

20

Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.

Fondo	Peso	Unità	Aggiornato al	Fonte
IWC · iShares Trust	0,02%	205.246 SH	11 Settembre 2026	Giornaliero
PRFZ · Invesco Exchange-Traded Fund Trust	0,00%	22.250 SH	29 Settembre 2026	Giornaliero
VXF · VANGUARD INDEX FUNDS	0,00%	615.799 SH	19 Agosto 2026	Giornaliero
VTI · VANGUARD INDEX FUNDS	0,00%	1.746.470 SH	19 Agosto 2026	Giornaliero
VHT · VANGUARD WORLD FUND	0,00%	153.712 SH	19 Agosto 2026	Giornaliero

PLRX Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo

21

rating · 10 analisti VENDI

Target mediano $2.00 +93,2%

0 0,0% Acquisto forte

0 0,0% Compra

6 60,0% Mantieni

2 20,0% Vendi

2 20,0% Vendita forte

Target Price a 12 Mesi

1 analisti · 2026-09-27

Target medio $2.00 +93,2%

Basso$2.00 Media$2.00 Alto$2.00

Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore

22

Base FY, prezzi alla chiusura dell'ultimo anno fiscale di ciascuna società.

Ticker	Capitalizzazione di Mercato	P/E	Rev YoY	Margine Netto	ROE	Margine lordo
PLRX	$75M	-0.5	-83.7%	·	-74.4%	·
NTHI	·	-2.6	-51.8%	·	·	·
TELO	$46M	-4.0	·	·	-325.7%	·
VRCA	$143M	-4.9	370.2%	-50.3%	-492.8%	·
RFL	·	-1.6	44.0%	-3328.2%	-34.6%	·
CING	·	·	·	·	·	·
ELOX	·	·	·	·	30.1%	·
HYPD	$31M	-0.4	1318.8%	-5570.6%	-115.6%	62.7%
TLPH	$56M	·	·	-51035.7%	-120.8%	·

Le Mie Metriche La tua watchlist personale — righe selezionate da Fondamentali Completi

26

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PLRX Pliant Therapeutics, Inc. - Common Stock