SPRB Spruce Biosciences, Inc. - Common Stock
$53,10
Prezzo · Ago 19, 2026
Fondamentali al Ago 12, 2026
Intervallo 52 sett.
$7–$240
20% of range
Rating Analisti
BUY
14 analysts
Prezzo Obiettivo
$148
+178% upside
P/E (TTM)
-1.0
ROE
-139.9%
Margine di Profitto Netto
—
SPRB Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane
Prezzo
$53.10
Capitalizzazione di Mercato
$73M
P/E (TTM)
-1.0
EPS (TTM)
$-50.83
Ricavi (TTM)
$0
Rendimento div.
—
ROE
-139.9%
D/E Debito/Patrimonio
0.0
Intervallo 52 sett.
$7 – $240
SPRB Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione
Configure
Performance decennale Andamento di ricavi, utile netto, margini e EPS
Ricavi e Utile Netto
$0
2022-12-31
→
2025-12-31
EPS
$-50.83
2021-12-31
→
2025-12-31
Flusso di cassa libero
—
2020-12-31
→
2024-12-31
Margini
—
Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?
Metrica
Tendenza 5 anni
SPRB
Mediana dei peer
P/E (TTM)
-1.0
—
P/B
1.7
1.2
EV / EBITDA
-0.7
—
Redditività Margini lordi, operativi e netti; ROE, ROA, ROIC
Metrica
Tendenza 5 anni
SPRB
Mediana dei peer
ROA
-79.3%
-85.8%
ROE
-139.9%
-122.3%
Salute finanziaria Debito, liquidità, solvibilità — solidità del bilancio
Metrica
Tendenza 5 anni
SPRB
Mediana dei peer
Debt / Equity (Debito / Patrimonio Netto)
0.0
—
Current Ratio (Rapporto corrente)
5.2
4.5
Quick Ratio
4.8
—
Crescita Crescita di ricavi, EPS e utile netto: YoY, CAGR 3Y, CAGR 5Y
Metrica
Tendenza 5 anni
SPRB
Mediana dei peer
Revenue YoY (Ricavi YoY)
-51.3%
—
Efficienza del Capitale Rotazione delle attività, rotazione delle scorte, rotazione dei crediti
Metrica
Tendenza 5 anni
SPRB
Mediana dei peer
SPRB Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo
COMPRA
14 analisti
- Acquisto forte 5 35,7%
- Compra 8 57,1%
- Mantieni 1 7,1%
- Vendi 0 0,0%
- Vendita forte 0 0,0%
Target Price a 12 Mesi
8 analisti · 2026-08-17
Mediana
$142.00
← Sotto tutti i target
$53.10
Basso
$104.00
Alto
$230.00
Target mediano
$142.00
+167,4%
Target medio
$147.88
+178,5%
Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili
Sorpresa media
-3.2%
| Periodo | EPS Actual | EPS Stimato | Sorpresa |
|---|---|---|---|
| 30 Giugno 2026 | $-6.68 | $-5.92 | -0.76% |
| 31 Marzo 2026 | $-8.94 | $-8.99 | 0.05% |
| 31 Dicembre 2025 | $-11.28 | $-8.15 | -3.1% |
| 30 Settembre 2025 | $-14.58 | $-14.21 | -0.37% |
| 30 Giugno 2025 | $-3.50 | $-19.51 | 16.0% |
| 31 Marzo 2025 | $-24.00 | $-16.42 | -7.6% |
| 31 Dicembre 2024 | $-42.75 | $-16.07 | -26.7% |
Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore
| Ticker | Capitalizzazione di Mercato | P/E | Rev YoY | Margine Netto | ROE | Margine lordo |
|---|---|---|---|---|---|---|
| SPRB | $120M | -1.7 | -51.3% | — | -139.9% | — |
| CNTN | $112M | -2.7 | — | — | -18.0% | — |
| HUMA | — | — | — | — | — | — |
| UNCY | $128M | -3.5 | -29.0% | — | -113.9% | — |
| EQ | $95M | -4.0 | 13.9% | — | -133.1% | — |
| HURA | — | -1.2 | — | — | — | — |
| IMDX | $215M | -4.5 | 115.6% | -1238.5% | 330.8% | 56.7% |
| INDP | $6M | -0.1 | — | — | -2820.8% | — |
| OTLK | $57M | -0.6 | — | -4416.2% | 193.1% | 4.0% |
| CBUS | — | -0.6 | -14.6% | -3492.3% | -223.0% | — |
Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario
Conto Economico 13
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue | $0 | $5M | $10M | $0 | |
| R&D Expense | $20M | $46M | $49M | $35M | |
| SG&A Expense | $17M | $15M | $13M | $12M | |
| Operating Expenses | $37M | $61M | $62M | $47M | |
| Operating Income | $-37M | $-56M | $-52M | $-47M | |
| Interest Expense | $90.0K | $307.0K | $483.0K | $420.0K | |
| Income Tax | $0 | $0 | $0 | $0 | |
| Net Income | $-39M | $-53M | $-48M | $-46M | |
| EPS (Basic) | $-50.83 | $-96.40 | $-1.24 | $-1.96 | |
| EPS (Diluted) | $-50.83 | $-96.40 | $-1.24 | $-1.96 | |
| Shares (Basic) | 766,598 | 550,146 | 38,510,220 | 23,527,116 | |
| Shares (Diluted) | 766,598 | 550,146 | 38,510,220 | 23,527,116 | |
| EBITDA | $-37M | $-56M | $-52M | $-47M |
Stato Patrimoniale 22
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $49M | $39M | $96M | $24M | |
| Short-term Investments | · | · | $0 | $55M | |
| Receivables | · | · | · | $0 | |
| Prepaid Expense | $353.0K | $3M | $4M | $3M | |
| Other Current Assets | $3M | $2M | $2M | $1M | |
| Current Assets | $52M | $44M | $102M | $84M | |
| Other Non-current Assets | $243.0K | $69.0K | $582.0K | $640.0K | |
| Total Assets | $53M | $45M | $104M | $86M | |
| Accounts Payable | $943.0K | $1M | $3M | $1M | |
| Accrued Liabilities | $9M | $12M | $15M | · | |
| Current Liabilities | $10M | $15M | $24M | $12M | |
| Capital Leases | $419.0K | $736.0K | $1M | $1M | |
| Other Non-current Liabilities | $0 | $282.0K | $236.0K | $161.0K | |
| Total Liabilities | $11M | $16M | $27M | $17M | |
| Long-term Debt | $0 | $2M | $4M | $6M | |
| Total Debt | $0 | $2M | $3M | $5M | |
| Common Stock | $0 | $0 | $4.0K | $3.0K | |
| Retained Earnings | $-289M | $-250M | $-197M | $-149M | |
| AOCI | · | · | $0 | $-558.0K | |
| Stockholders' Equity | $43M | $29M | $77M | $68M | |
| Liabilities + Equity | $53M | $45M | $104M | $86M | |
| Shares Outstanding | 1,372,043 | 563,042 | 547,019 | 23,601,004 |
Flusso di cassa 9
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| D&A | $21.0K | $46.0K | $70.0K | $74.0K | |
| Stock-based Comp | $3M | $5M | $5M | $4M | |
| Operating Cash Flow | $-33M | $-56M | $-33M | $-42M | |
| CapEx | · | $0 | $7.0K | $8.0K | |
| Investing Cash Flow | · | $0 | $56M | $24M | |
| Debt Issued | · | · | · | $0 | |
| Net Debt Issued | $-2M | $-2M | $-2M | $0 | |
| Financing Cash Flow | $43M | $-2M | $49M | $-241.0K | |
| Free Cash Flow | · | $-56M | $-33M | $-42M |
Redditività 5
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Operating Margin | · | -1143.4% | -515.3% | · | |
| Net Margin | · | -1079.9% | -475.0% | · | |
| EBITDA Margin | · | -1143.4% | -515.3% | · | |
| ROA | -79.3% | -71.1% | -50.5% | -43.5% | |
| ROE | -139.9% | -131.8% | -59.2% | -62.8% |
Liquidità e Solvibilità 5
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 5.2 | 2.9 | 4.2 | 6.7 | |
| Quick Ratio | 4.8 | 2.5 | 3.9 | 6.4 | |
| Debt / Equity | 0.0 | 0.1 | 0.0 | 0.1 | |
| LT Debt / Equity | 0.0 | 0.0 | 0.0 | 0.0 | |
| Interest Coverage | -405.7 | -182.9 | -107.6 | -112.6 |
Efficienza 1
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.1 | 0.1 | · |
Tassi di Crescita 1
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue YoY | · | -51.3% | · | · |
Valutazione (TTM) 14
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue TTM | $0 | $5M | $10M | $0 | |
| Net Income TTM | $-39M | $-53M | $-48M | $-46M | |
| Market Cap | $120M | $99.77B | $676.22B | $145.63B | |
| Enterprise Value | $71M | $99.73B | $676.13B | $145.56B | |
| P/E | -1.7 | -24.5 | -13291.3 | -3148.3 | |
| P/S | · | 20315.9 | 67025.8 | · | |
| P/B | 2.8 | 3461.8 | 8838.5 | 2126.5 | |
| P / Tangible Book | 2.8 | 3461.8 | 8838.5 | 2126.5 | |
| P / Cash Flow | -3.6 | -1782.8 | -20322.3 | -3493.8 | |
| P / FCF | · | -1782.8 | -20318.0 | -3493.2 | |
| EV / EBITDA | -1.9 | -1776.2 | -13004.2 | -3078.5 | |
| EV / FCF | · | -1782.1 | -20315.2 | -3491.4 | |
| EV / Revenue | · | 20308.4 | 67016.5 | · | |
| Earnings Yield | -58.4% | -4.1% | -0.01% | -0.03% |
Conto Economico 13
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | $0 | $0 | $0 | $0 | $697.0K | $602.0K | $2M | $2M | $3M | $3M | $2M | $2M | $0 | $0 | |
| R&D Expense | $12M | $8M | $4M | $5M | $-430.0K | $11M | $21M | $7M | $8M | $10M | $11M | $13M | $13M | $12M | $9M | $9M | |
| SG&A Expense | $4M | $4M | $7M | $3M | $3M | $4M | $3M | $3M | $4M | $4M | $3M | $3M | $3M | $3M | $3M | $3M | |
| Operating Expenses | $17M | $12M | $11M | $8M | $3M | $14M | $25M | $10M | $12M | $15M | $14M | $17M | $16M | $15M | $12M | $12M | |
| Operating Income | $-17M | $-12M | $-11M | $-8M | $-3M | $-14M | $-24M | $-9M | $-10M | $-13M | $-11M | $-14M | $-14M | $-13M | $-12M | $-12M | |
| Interest Expense | $1M | $674.0K | $6.0K | $19.0K | $29.0K | $36.0K | $56.0K | $71.0K | $83.0K | $97.0K | $106.0K | $119.0K | $127.0K | $131.0K | $129.0K | $110.0K | |
| Other Non-op | · | · | · | · | · | · | · | $808.0K | $938.0K | $1M | · | $1M | $1M | $539.0K | · | · | |
| Net Income | $-16M | $-12M | $-15M | $-8M | $-2M | $-14M | $-24M | $-9M | $-9M | $-12M | $-10M | $-12M | $-13M | $-13M | $-11M | $-11M | |
| EPS (Basic) | $-6.68 | $-8.94 | $-32.43 | $-14.58 | $-3.50 | $-23.95 | $-63.64 | $-15.75 | $-16.73 | $-0.28 | $-0.22 | $-0.30 | $-0.32 | $-0.40 | $-0.47 | $-0.48 | |
| EPS (Diluted) | $-6.68 | $-8.94 | $-32.43 | $-14.58 | $-3.50 | $-23.95 | $-63.64 | $-15.75 | $-16.73 | $-0.28 | $-0.22 | $-0.30 | $-0.32 | $-0.40 | $-0.47 | $-0.48 | |
| Shares (Basic) | 2,431,075 | 1,372,084 | -44,332,551 | 563,066 | 591,137 | 586,142 | -41,645,519 | 550,645 | 548,789 | 41,096,231 | -74,648,557 | 40,710,692 | 40,547,925 | 31,900,160 | -47,019,042 | 23,560,250 | |
| Shares (Diluted) | 2,431,075 | 1,372,084 | -44,332,551 | 563,066 | 591,137 | 586,142 | -41,645,519 | 550,645 | 548,789 | 41,096,231 | -74,648,557 | 40,710,692 | 40,547,925 | 31,900,160 | -47,019,042 | 23,560,250 | |
| EBITDA | $-17M | $-12M | · | $-8M | $-3M | $-14M | · | $-9M | $-10M | $-13M | · | $-14M | $-14M | $-13M | · | $-12M |
Stato Patrimoniale 22
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $96M | $54M | $49M | $11M | $16M | $26M | $39M | $60M | $70M | $81M | $96M | $99M | $97M | $74M | $24M | $22M | |
| Short-term Investments | · | · | · | · | · | · | · | · | · | · | · | $9M | $23M | $45M | $55M | $69M | |
| Receivables | · | · | · | · | · | · | · | · | · | · | · | · | · | $15M | · | · | |
| Prepaid Expense | $5M | $864.0K | $353.0K | $932.0K | $2M | $3M | $3M | $3M | $3M | $3M | $4M | $3M | $3M | $3M | $3M | $3M | |
| Other Current Assets | $234.0K | $88.0K | $3M | $3M | $3M | $2M | $2M | $860.0K | $2M | $2M | $2M | $419.0K | $206.0K | $253.0K | $1M | · | |
| Current Assets | $101M | $55M | $52M | $15M | $21M | $31M | $44M | $64M | $74M | $86M | $102M | $111M | $124M | $137M | $84M | $93M | |
| Other Non-current Assets | $1M | $539.0K | $243.0K | $62.0K | $64.0K | $204.0K | $69.0K | $531.0K | $547.0K | $553.0K | $582.0K | $607.0K | $536.0K | $525.0K | $640.0K | $667.0K | |
| Total Assets | $103M | $56M | $53M | $15M | $22M | $32M | $45M | $65M | $76M | $88M | $104M | $113M | $126M | $139M | $86M | $95M | |
| Accounts Payable | $1M | $3M | $943.0K | $1M | $807.0K | $2M | $1M | $2M | $682.0K | $2M | $3M | $3M | $945.0K | $3M | $1M | $2M | |
| Accrued Liabilities | $7M | $8M | $9M | $8M | $6M | $12M | $12M | $8M | $11M | · | $15M | · | · | · | · | · | |
| Current Liabilities | $11M | $12M | $10M | $9M | $8M | $16M | $15M | $12M | $14M | $18M | $24M | $24M | $23M | $23M | $12M | $12M | |
| Capital Leases | $245.0K | $332.0K | $419.0K | $500.0K | $580.0K | $659.0K | $736.0K | · | · | $950.0K | $1M | · | · | · | $1M | $998.0K | |
| Other Non-current Liabilities | · | · | $0 | $0 | $0 | $0 | $282.0K | $273.0K | $262.0K | $250.0K | $236.0K | $220.0K | $202.0K | $181.0K | $161.0K | $139.0K | |
| Total Liabilities | $19M | $22M | $11M | $10M | $9M | $16M | $16M | $13M | $16M | $21M | $27M | $28M | $29M | $31M | $17M | $17M | |
| Long-term Debt | $20M | $20M | $0 | $549.0K | $972.0K | $1M | $2M | $2M | $3M | $3M | $3M | $4M | $5M | $5M | $5M | $6M | |
| Total Debt | $7M | $6M | · | $539.0K | $943.0K | $1M | · | $2M | $3M | $3M | · | $4M | $4M | $5M | · | $5M | |
| Common Stock | $0 | $0 | $0 | $0 | $0 | $4.0K | $0 | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $3.0K | $3.0K | |
| Retained Earnings | $-318M | $-302M | $-289M | $-275M | $-266M | $-264M | $-250M | $-227M | $-218M | $-209M | $-197M | $-187M | $-175M | $-162M | $-149M | $-138M | |
| AOCI | · | · | · | · | · | · | · | · | · | · | · | $-3.0K | $-55.0K | $-188.0K | $-558.0K | $-873.0K | |
| Stockholders' Equity | $84M | $35M | $43M | $5M | $13M | $15M | $29M | $52M | $59M | $67M | $77M | $85M | $97M | $108M | $68M | $78M | |
| Liabilities + Equity | $103M | $56M | $53M | $15M | $22M | $32M | $45M | $65M | $76M | $88M | $104M | $113M | $126M | $139M | $86M | $95M | |
| Shares Outstanding | 2,752,810 | 1,372,278 | 1,372,043 | 563,491 | 563,042 | 42,231,285 | 563,042 | 41,302,599 | 41,302,599 | 41,154,799 | 41,029,832 | 40,710,692 | 40,710,692 | 39,746,116 | 23,601,004 | 23,560,250 |
Flusso di cassa 9
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $631.0K | $252.0K | $5.0K | $3.0K | $7.0K | $6.0K | $9.0K | $10.0K | $12.0K | $15.0K | $16.0K | $17.0K | $18.0K | $19.0K | $24.0K | $23.0K | |
| Stock-based Comp | $871.0K | $689.0K | $2M | $415.0K | $-77.0K | $544.0K | $961.0K | $1M | $2M | $2M | $1M | $1M | $1M | $1M | $802.0K | $783.0K | |
| Operating Cash Flow | $-22M | $-9M | $-6M | $-5M | $-9M | $-13M | $-21M | $-9M | $-11M | $-15M | $-11M | $-12M | $2M | $-12M | $-12M | $-9M | |
| CapEx | $135.0K | $10.0K | · | · | $0 | $0 | · | · | · | · | $0 | $7.0K | · | · | $0 | $2.0K | |
| Investing Cash Flow | $-135.0K | $-10.0K | · | · | $0 | $0 | · | $0 | $0 | $0 | $9M | $14M | $22M | $10M | $15M | $-17M | |
| Debt Issued | $0 | $14M | · | · | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Net Debt Issued | · | $14M | · | · | · | $-405.0K | · | · | · | $-405.0K | · | · | · | $-405.0K | · | · | |
| Financing Cash Flow | $64M | $14M | $45M | $-402.0K | $-400.0K | $-411.0K | $-625.0K | $-405.0K | $-365.0K | $-227.0K | $-552.0K | $-405.0K | $-432.0K | $51M | $36.0K | $-90.0K | |
| Free Cash Flow | · | $-9M | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
Redditività 5
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | -1562.8% | -623.4% | -631.0% | · | -444.4% | -645.4% | -672.1% | · | · | |
| Net Margin | · | · | · | · | · | · | · | -1440.4% | -570.2% | -580.7% | · | -402.0% | -592.3% | -651.3% | · | · | |
| EBITDA Margin | · | · | · | · | · | · | · | -1562.8% | -623.4% | -631.0% | · | -444.4% | -645.4% | -672.1% | · | · | |
| ROA | -26.0% | -27.9% | · | -20.4% | -4.2% | -23.6% | · | -9.7% | -9.1% | -10.3% | · | -11.9% | -11.1% | -10.1% | · | -9.9% | |
| ROE | -33.5% | -49.1% | · | -28.8% | -5.7% | -34.3% | · | -12.7% | -11.8% | -13.3% | · | -15.1% | -13.8% | -12.3% | · | -11.5% |
Liquidità e Solvibilità 5
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 9.2 | 4.7 | · | 1.5 | 2.6 | 2.0 | · | 5.4 | 5.2 | 4.7 | · | 4.6 | 5.5 | 6.0 | · | 7.8 | |
| Quick Ratio | 8.8 | 4.6 | · | 1.1 | 2.0 | 1.6 | · | 5.1 | 4.9 | 4.4 | · | 4.5 | 5.3 | 5.8 | · | 7.5 | |
| Debt / Equity | 0.1 | 0.2 | · | 0.1 | 0.1 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.1 | |
| LT Debt / Equity | 0.1 | 0.2 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | |
| Interest Coverage | -15.1 | -17.8 | · | -433.1 | -92.8 | -402.6 | · | -132.5 | -120.9 | -130.2 | · | -114.8 | -110.0 | -100.8 | · | -105.1 |
Efficienza 2
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · | |
| Receivables Turnover | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.3 | · | · |
Valutazione (TTM) 14
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $602.0K | $602.0K | · | $602.0K | $2M | $4M | · | $7M | $9M | $9M | · | $7M | $4M | $2M | · | · | |
| Net Income TTM | $-39M | $-37M | · | $-33M | $-34M | $-44M | · | $-42M | $-46M | $-50M | · | $-49M | $-49M | $-48M | · | $-46M | |
| Market Cap | $149M | $90M | · | $5M | $231M | $68.89B | · | $110.36B | $120.35B | $181.96B | · | $517.53B | $492.34B | $494.09B | · | $181.56B | |
| Enterprise Value | $59M | $42M | · | $-5M | $216M | $68.87B | · | $110.30B | $120.28B | $181.88B | · | $517.43B | $492.23B | $493.98B | · | $181.48B | |
| P/E | -1.6 | -1.3 | · | -0.3 | -11.3 | -49.3 | · | -80.8 | -165.3 | -3401.0 | · | -8475.0 | -7072.4 | -6577.4 | · | -3892.0 | |
| P/S | 246.9 | 149.0 | · | 8.4 | 104.5 | 16347.8 | · | 15144.1 | 13598.4 | 19769.2 | · | 71859.9 | 119240.7 | 251575.3 | · | · | |
| P/B | 1.8 | 2.6 | · | 0.9 | 17.5 | 4495.5 | · | 2137.1 | 2033.9 | 2731.1 | · | 6061.5 | 5098.8 | 4575.1 | · | 2313.6 | |
| P / Tangible Book | 1.8 | 2.6 | · | 0.9 | 17.5 | 4495.5 | · | 2137.1 | 2033.9 | 2731.1 | · | 6061.5 | 5098.8 | 4575.1 | · | 2313.6 | |
| P / Cash Flow | · | -10.3 | · | · | · | -5412.9 | · | · | · | -12164.4 | · | · | · | -41907.9 | · | · | |
| P / FCF | · | -10.3 | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| EV / EBITDA | -3.6 | -3.5 | · | 0.6 | -80.1 | -4752.0 | · | -11723.8 | -11984.7 | -14397.0 | · | -37884.8 | -35229.6 | -37425.6 | · | -15702.7 | |
| EV / FCF | · | -4.8 | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| EV / Revenue | 98.8 | 69.9 | · | -8.4 | 97.5 | 16342.1 | · | 15136.2 | 13590.8 | 19760.7 | · | 71845.4 | 119212.5 | 251517.2 | · | · | |
| Earnings Yield | -62.4% | -78.0% | · | -381.6% | -8.8% | -2.0% | · | -1.2% | -0.61% | -0.03% | · | -0.01% | -0.01% | -0.02% | · | -0.03% |
Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni
Conto Economico
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ricavi | $0 | $5M | $10M | $0 | — |
| Margine Operativo % | — | -1143.4% | -515.3% | — | — |
| Utile netto | $-39M | $-53M | $-48M | $-46M | $-42M |
| EPS Diluito | $-50.83 | $-96.40 | $-1.24 | $-1.96 | $-1.81 |
Stato Patrimoniale
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Debito / Patrimonio Netto | 0.0 | 0.1 | 0.0 | 0.1 | 0.0 |
| Rapporto corrente | 5.2 | 2.9 | 4.2 | 6.7 | 10.4 |
| Quick Ratio | 4.8 | 2.5 | 3.9 | 6.4 | 10.0 |
Flusso di cassa
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flusso di cassa libero | — | $-56M | $-33M | $-42M | $-36M |
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Proprietari istituzionali (13F) 64 filer · $85.1M totale · Aggiornato al 30 Giugno 2026
Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.
Attività istituzionale — Q2 2026 vs trimestre precedente
| Nuove posizioni | Posizioni chiuse | Aumentato | Diminuito | Variazione netta delle azioni |
|---|---|---|---|---|
| 36 (+25 vs trimestre precedente) | 4 (-5 vs trimestre precedente) | 14 (+8 vs trimestre precedente) | 5 (0 vs trimestre precedente) | +890K |
Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.
| Istituzione | Valore | Azioni | % di 13F tracciati | Tipo |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | $10.800.000 | 200.000 | 12,69% | Azioni |
| MILLENNIUM MANAGEMENT LLC | $8.692.974 | 160.981 | 10,22% | Azioni |
| Ikarian Capital, LLC | $6.553.224 | 121.356 | 7,70% | Azioni |
| VANGUARD CAPITAL MANAGEMENT LLC | $6.443.874 | 119.331 | 7,57% | Azioni |
| Alyeska Investment Group, L.P. | $4.410.234 | 81.671 | 5,18% | Azioni |
| ADAR1 Capital Management, LLC | $3.656.718 | 67.717 | 4,30% | Azioni |
| AIGH Capital Management LLC | $3.302.532 | 61.158 | 3,88% | Azioni |
| Cable Car Capital, LP | $3.240.000 | 60.000 | 3,81% | Azioni |
| GEODE CAPITAL MANAGEMENT, LLC | $3.228.503 | 59.780 | 3,79% | Azioni |
| STATE STREET CORP | $2.724.300 | 50.450 | 3,20% | Azioni |
| CITADEL ADVISORS LLC | $2.535.840 | 46.960 | 2,98% | Azioni |
| BOOTHBAY FUND MANAGEMENT, LLC | $2.272.320 | 42.080 | 2,67% | Azioni |
| STEMPOINT CAPITAL LP | $2.234.952 | 41.388 | 2,63% | Azioni |
| Eversept Partners, LP | $2.160.000 | 40.000 | 2,54% | Azioni |
| Carlyle Group Inc. | $2.085.493 | 38.620 | 2,45% | Azioni |
| Affinity Asset Advisors, LLC | $1.620.000 | 30.000 | 1,90% | Azioni |
| DIADEMA PARTNERS LP | $1.620.000 | 30.000 | 1,90% | Azioni |
| Stonepine Capital Management, LLC | $1.554.930 | 28.795 | 1,83% | Azioni |
| Point72 Asset Management, L.P. | $1.527.012 | 28.278 | 1,79% | Azioni |
| GOLDMAN SACHS GROUP INC | $1.480.086 | 27.409 | 1,74% | Azioni |
| Quinn Opportunity Partners LLC | $1.447.740 | 26.810 | 1,70% | Azioni |
| UBS Group AG | $1.262.574 | 23.381 | 1,48% | Azioni |
| ExodusPoint Capital Management, LP | $1.188.000 | 22.000 | 1,40% | Azioni |
| Knott David M Jr | $1.080.000 | 20.000 | 1,27% | Azioni |
| Rosalind Advisors, Inc. | $1.080.000 | 20.000 | 1,27% | Azioni |
| AMERIPRISE FINANCIAL INC | $1.017.036 | 18.834 | 1,20% | Azioni |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $998.784 | 18.496 | 1,17% | Azioni |
| VANGUARD FIDUCIARY TRUST CO | $991.494 | 18.361 | 1,17% | Azioni |
| Balyasny Asset Management L.P. | $655.452 | 12.138 | 0,77% | Azioni |
| DIMENSIONAL FUND ADVISORS LP | $429.732 | 7.958 | 0,51% | Azioni |
| Persistent Asset Partners Ltd | $414.558 | 7.677 | 0,49% | Azioni |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $387.828 | 7.182 | 0,46% | Azioni |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $318.384 | 5.896 | 0,37% | Azioni |
| RENAISSANCE TECHNOLOGIES LLC | $253.800 | 4.700 | 0,30% | Azioni |
| Pale Fire Capital SE | $206.172 | 3.818 | 0,24% | Azioni |
| RHUMBLINE ADVISERS | $190.026 | 3.519 | 0,22% | Azioni |
| DEUTSCHE BANK AG\ | $143.208 | 2.652 | 0,17% | Azioni |
| WELLS FARGO & COMPANY/MN | $125.766 | 2.329 | 0,15% | Azioni |
| Bank of New York Mellon Corp | $120.798 | 2.237 | 0,14% | Azioni |
| NEW YORK STATE COMMON RETIREMENT FUND | $102.600 | 1.900 | 0,12% | Azioni |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $67.608 | 1.252 | 0,08% | Azioni |
| JPMORGAN CHASE & CO | $62.977 | 1.127 | 0,07% | Azioni |
| CITIGROUP INC | $59.832 | 1.108 | 0,07% | Azioni |
| Lion Point Capital, LP | $54.000 | 1.000 | 0,06% | Azioni |
| Police & Firemen's Retirement System of New Jersey | $46.656 | 864 | 0,05% | Azioni |
| VANGUARD GROUP INC | $39.374 | 452 | 0,05% | Azioni |
| BNP PARIBAS FINANCIAL MARKETS | $24.462 | 453 | 0,03% | Azioni |
| Vanguard Global Advisers, LLC | $24.408 | 452 | 0,03% | Azioni |
| NORTHERN TRUST CORP | $22.950 | 425 | 0,03% | Azioni |
| BARCLAYS PLC | $20.574 | 381 | 0,02% | Azioni |
| FMR LLC | $18.522 | 343 | 0,02% | Azioni |
| BlackRock, Inc. | $18.360 | 340 | 0,02% | Azioni |
| Legal & General Group Plc | $14.219 | 264 | 0,02% | Azioni |
| Ameritas Investment Partners, Inc. | $13.338 | 247 | 0,02% | Azioni |
| Tower Research Capital LLC (TRC) | $13.284 | 246 | 0,02% | Azioni |
| Russell Investments Group, Ltd. | $11.718 | 217 | 0,01% | Azioni |
| SBI Securities Co., Ltd. | $10.854 | 201 | 0,01% | Azioni |
| ROYAL BANK OF CANADA | $6.000 | 120 | 0,01% | Azioni |
| Sterling Capital Management LLC | $2.322 | 43 | 0,00% | Azioni |
| JONES FINANCIAL COMPANIES LLLP | $1.653 | 30 | 0,00% | Azioni |
| CALDWELL SUTTER CAPITAL, INC. | $702 | 13 | 0,00% | Azioni |
| Friedenthal Financial | $378 | 7 | 0,00% | Azioni |
| MORGAN STANLEY | $108 | 2 | 0,00% | Azioni |
| Cassaday & Co Wealth Management LLC | $108 | 2 | 0,00% | Azioni |
Insider aziendali 19 insider · 6 dirigenti · 10 direttori
| Insider | Ruolo | Ultima attività | Azioni possedute | Acquisti 12m | Vendite 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Javier B. Szwarcberg | CHIEF EXECUTIVE OFFICER | 30 Giugno 2026 A | 19.270 | 0 | 0 | $0 |
| Richard King | Chief Executive Officer | 30 Giugno 2021 J | 2.230 | 0 | 0 | $0 |
| Samir M. Gharib | President & CFO | 29 Dicembre 2023 A | 202.776 | 0 | 0 | $0 |
| Adrian W Quartel | Chief Medical Officer | 27 Luglio 2026 A | — | 0 | 0 | $0 |
| Ralph William Charlton III | Chief Medical Officer | 29 Dicembre 2023 A | 55.373 | 0 | 0 | $0 |
| Subaweerage Dias | Chief Medical Officer | 16 Dicembre 2021 A | — | 0 | 0 | $0 |
| Percival Barretto-Ko | Direttore | 25 Maggio 2023 A | — | 0 | 0 | $0 |
| Kirk Ways | Direttore | 25 Maggio 2023 A | — | 0 | 0 | $0 |
| Camilla V Simpson | Direttore | 25 Maggio 2023 A | 0 | 0 | 0 | $0 |
| Bali Muralidhar | Direttore | 25 Maggio 2023 A | 1.792.518 | 0 | 0 | $0 |
| Niall O'Donnell, Ph.D. | Direttore | 25 Maggio 2023 A | 1.326.305 | 0 | 0 | $0 |
| Tiba Aynechi | Direttore | 25 Maggio 2023 A | — | 0 | 0 | $0 |
| Moghrabi Dina Chaya | Direttore | 25 Maggio 2022 A | 2.161.022 | 0 | 0 | $0 |
| Jonas Hansson | Direttore | 14 Ottobre 2020 C | 2.033.621 | 0 | 0 | $0 |
| Parkman Healthcare Partners LLC | Proprietario del 10% | 06 Ottobre 2025 S | 1.050 | 1 | 2 | $-336 |
| Novo Holdings A/S | Proprietario del 10% | 21 Marzo 2024 S | 2.550.000 | 0 | 0 | $0 |
| Michael G Grey | — | 21 Maggio 2026 A | — | 0 | 0 | $0 |
| Daniel K Spiegelman | — | 21 Maggio 2026 A | — | 0 | 0 | $0 |
| HealthCap VIII, L.P. | — | 14 Ottobre 2020 C | 2.033.621 | 0 | 0 | $0 |
Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato
Attivisti e proprietari del 5%+ 6 partecipazioni
Investitori che hanno depositato SEC Schedule 13D — proprietà effettiva superiore al 5% con l'intento di influenzare l'emittente (partecipazioni attiviste, campagne per il consiglio di amministrazione, M&A). Ogni riga mostra lo stato più recente noto della posizione di quel depositante.
| Depositante | Depositato | Partecipazione | Stato | Scopo | Deposito |
|---|---|---|---|---|---|
| HealthCap VIII, L.P., HealthCap VIII GP LLC ×4 depositi | 09 Ottobre 2025 | 3,40% | Modifica | — | SEC |
| RiverVest Venture Fund III, L.P., RiverVest Venture Fund III (Ohio), L.P., RiverVest Venture Partners III (Ohio), LLC, RiverVest Venture Partners III, L.P., RiverVest Venture Partners III, LLC, RiverVest Venture Fund IV, L.P., RiverVest Venture Partners IV, L.P., RiverVest Venture Partners IV, LLC, John P. McKearn, Ph.D., Jay Schmelter, Thomas C. Melzer, Niall O'Donnell, Ph.D. | 10 Gennaio 2025 | 4,20% | Modifica | — | SEC |
| Novo Holdings A/S ×9 depositi | 28 Marzo 2024 | — | Deposito iniziale | — | SEC |
| Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata | 30 Maggio 2023 | — | Deposito iniziale | — | SEC |
| Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata | 23 Ottobre 2020 | — | Deposito iniziale | Investimento passivo | SEC |
| Abingworth LLP, Abingworth Bioventures VII, LP | 16 Ottobre 2020 | — | Deposito iniziale | Campagna per il consiglio di amministrazione | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Proprietà ETF Posseduti da 13 ETF
Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.
| Fondo | Peso | Unità | Aggiornato al | Fonte |
|---|---|---|---|---|
| QQQS · Invesco Exchange-Traded Fund Trust … | 0,45% | 2.182 SH | 08 Agosto 2026 | Giornaliero |
| IWC · iShares Trust | 0,03% | 9.122 SH | 08 Agosto 2026 | Giornaliero |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,01% | 1.758 SH | 08 Agosto 2026 | Giornaliero |
| IWN · iShares Trust | 0,01% | 17.564 SH | 08 Agosto 2026 | Giornaliero |
| IWM · iShares Trust | 0,00% | 67.341 SH | 08 Agosto 2026 | Giornaliero |
| IWO · iShares Trust | 0,00% | 6.379 SH | 08 Agosto 2026 | Giornaliero |
| DFAS · Dimensional ETF Trust | 0,00% | 1.283 NS | 30 Aprile 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 681 NS | 30 Aprile 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 31.892 SH | 08 Agosto 2026 | Giornaliero |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 84.935 SH | 08 Agosto 2026 | Giornaliero |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,00% | 15.701 SH | 08 Agosto 2026 | Giornaliero |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,00% | 748 SH | 08 Agosto 2026 | Giornaliero |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 289 SH | 08 Agosto 2026 | Giornaliero |