ZYME Zymeworks Inc. - Common Stock
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Zymeworks Inc. is a publicly held biotechnology company based in Vancouver, British Columbia, that develops protein therapeutics for the treatment of cancer as well as for autoimmune and inflammatory diseases. The products are based upon the company's molecular modeling software for optimizing protein structure. In 2014, Zymeworks raised $44 million across various funding rounds according to PitchBook, placing it among the top 10 HealthTech businesses in the world to raise the most capital that year. In May 2017, Zymeworks held an IPO on the Toronto Stock Exchange, raising $59 million. This was the largest Canadian biotech IPO in more than a decade. By alphabetical order, Zymeworks is the last company on the Toronto Stock Exchange.
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Zymeworks Inc. is a publicly held biotechnology company based in Vancouver,
British Columbia, that develops protein therapeutics for the treatment of cancer as well as for autoimmune and inflammatory diseases. The products are based upon the company's molecular modeling software for optimizing protein structure. In 2014, Zymeworks raised $44 million across various funding rounds according to PitchBook, placing it among the top 10 HealthTech businesses in the world to raise the most capital that year. In May 2017, Zymeworks held an IPO on the Toronto Stock Exchange, raising $59 million. This was the largest Canadian biotech IPO in more than a decade. By alphabetical order, Zymeworks is the last company on the Toronto Stock Exchange.
In May 2019, Zymeworks announced that GSK has expanded its 2016 licensing and collaboration agreement for the research, development and commercialization of bispecific antibodies across multiple disease areas. The extended agreement has meant that GSK can have access to Zymeworks' heavy-light chain pairing technology, which enables the development of bispecific and multifunctional therapeutics.
In September 2019, Zymeworks announced that, following their clinical trials, it has been confirmed that their ZW25 monotherapy can provide durable disease control in patients with a variety of HER2-expressing solid tumors that have progressed following standard of care treatments.
In May 2022, Zymeworks rejected an unsolicited takeover proposal from a Dubai hedge fund, All Blue Falcons FZE, an arm of All Blue Capital.
Azymetric
This is an IgG1-based heterodimeric antibody scaffold that consists of two different heavy chains engineered to exclusively assemble into a single molecule, allowing bi-specific binding to two different antigens or drug targets. The Azymetric scaffold is engineered by making amino acid changes in the CH3 region of the constant Fc domain of the IgG1. This scaffold can also be engineered with tailored effector function and optimized serum half-life.
Awards and recognition
Deal of the Year, Lifesciences BC Awards, 2018
Life Sciences Company of the Year, Lifesciences BC Awards, 2016
Emerging company of the year – Health, BIOTECanada Gold Leaf Awards, 2015
12th Place, BC's Leading Innovators, 2011
Life Science Emerging Rocket, 2009, 2010, 2011
Early stage Company of the year – Industrial & Agriculture, BIOTECanada Gold Leaf Awards, 2009
== References ==
Fonte: Wikipedia (Inglese), CC BY-SA 4.0 · Vedi su Wikipedia ↗
ZYME Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane
ZYME Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione
Performance decennale Andamento di ricavi, utile netto, margini e EPS
Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?
Redditività Margini lordi, operativi e netti; ROE, ROA, ROIC
Salute finanziaria Debito, liquidità, solvibilità — solidità del bilancio
Crescita Crescita di ricavi, EPS e utile netto: YoY, CAGR 3Y, CAGR 5Y
Efficienza del Capitale Rotazione delle attività, rotazione delle scorte, rotazione dei crediti
ZYME Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo
- Acquisto forte 6 33,3%
- Compra 11 61,1%
- Mantieni 1 5,6%
- Vendi 0 0,0%
- Vendita forte 0 0,0%
Target Price a 12 Mesi
12 analisti · 2026-08-16Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili
| Periodo | EPS Actual | EPS Stimato | Sorpresa |
|---|---|---|---|
| 30 Giugno 2026 | $-0.62 | $-0.50 | -0.12% |
| 31 Marzo 2026 | $-0.59 | $-0.20 | -0.39% |
| 31 Dicembre 2025 | $-0.55 | $-0.42 | -0.13% |
| 30 Settembre 2025 | $-0.26 | $-0.33 | 0.07% |
| 30 Giugno 2025 | $0.03 | $-0.50 | 0.53% |
| 31 Marzo 2025 | $-0.30 | $-0.42 | 0.12% |
Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore
| Ticker | Capitalizzazione di Mercato | P/E | Rev YoY | Margine Netto | ROE | Margine lordo |
|---|---|---|---|---|---|---|
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
| AUPH | $2.11B | 7.7 | 20.4% | 101.5% | 62.7% | — |
| ABUS | $926M | -28.3 | 128.2% | -237.9% | -42.0% | — |
| ACOG | $141M | -5.5 | — | -202.2% | -43.8% | — |
| PMN | $15M | -0.3 | — | — | 4840.3% | — |
| XENE | $3.59B | -10.3 | — | -4612.1% | -56.9% | — |
Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario
Conto Economico 14
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue | $106M | $76M | $76M | $412M | $27M | |
| R&D Expense | · | · | $144M | $209M | $200M | |
| SG&A Expense | $62M | $62M | $70M | $73M | $43M | |
| Operating Expenses | $199M | $213M | $214M | $282M | $242M | |
| Operating Income | $-93M | $-137M | $-138M | $131M | $-216M | |
| Other Non-op | $51.0K | $-218.0K | $291.0K | $-42.0K | $118.0K | |
| Pretax Income | $-80M | $-117M | $-119M | $135M | $-212M | |
| Income Tax | $1M | $6M | $-568.0K | $11M | $-516.0K | |
| Net Income | $-81M | $-123M | $-119M | $124M | $-212M | |
| EPS (Basic) | $-1.08 | $-1.62 | $-1.72 | $1.91 | $-4.11 | |
| EPS (Diluted) | $-1.08 | $-1.62 | $-1.72 | $1.90 | $-4.61 | |
| Shares (Basic) | 75,404,897 | 75,846,681 | 68,863,010 | 65,194,775 | 51,553,869 | |
| Shares (Diluted) | 75,413,396 | 75,878,738 | 68,863,010 | 65,249,184 | 52,131,596 | |
| EBITDA | $-93M | $-137M | $-138M | · | · |
Stato Patrimoniale 23
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Cash & Equivalents | $41M | $66M | $158M | $401M | $202M | |
| Short-term Investments | · | · | $217M | $91M | $51M | |
| Receivables | $5M | $56M | $19M | $33M | $16M | |
| Prepaid Expense | $15M | $19M | $19M | $19M | $20M | |
| Current Assets | $249M | $300M | $413M | $545M | $288M | |
| PP&E (Net) | $16M | $18M | $20M | $25M | $23M | |
| PP&E (Gross) | $36M | $35M | $41M | $38M | $37M | |
| Accum. Depreciation | $21M | $18M | $21M | $13M | $14M | |
| Goodwill | $12M | $12M | $12M | $12M | $12M | |
| Intangibles | $1M | $5M | $8M | $9M | $4M | |
| Total Assets | $347M | $463M | $581M | $649M | $389M | |
| Accounts Payable | $36M | $60M | $46M | $87M | $63M | |
| Current Liabilities | $42M | $88M | $56M | $96M | $72M | |
| Capital Leases | $15M | $16M | $22M | $25M | $31M | |
| Deferred Tax | $6M | $5M | $3M | $2M | $2M | |
| Other Non-current Liabilities | $278.0K | $923.0K | $2M | $3M | $3M | |
| Total Liabilities | $78M | $124M | $116M | $156M | $140M | |
| Common Stock | $1.11B | $1.02B | $997M | $886M | $741M | |
| Retained Earnings | $-953M | $-830M | $-677M | $-559M | $-683M | |
| AOCI | $-6M | $-7M | $-7M | $-7M | $-7M | |
| Stockholders' Equity | $269M | $339M | $465M | $493M | $249M | |
| Liabilities + Equity | $347M | $463M | $581M | $649M | $389M | |
| Shares Outstanding | 74,638,413 | 68,964,319 | 70,115,997 | 63,059,501 | 46,633,935 |
Flusso di cassa 14
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Stock-based Comp | $28M | $18M | $8M | $4M | $11M | |
| Deferred Tax | $945.0K | $691.0K | $-757.0K | $2M | $-953.0K | |
| Amort. of Intangibles | $4M | $4M | $3M | $1M | $3M | |
| Restructuring | · | · | $0 | · | · | |
| Operating Cash Flow | $-33M | $-110M | $-118M | $144M | $-192M | |
| CapEx | $2M | $2M | $2M | $8M | $12M | |
| Investing Cash Flow | $27M | $39M | $-207M | $-54M | $145M | |
| Stock Issued | $0 | $0 | $26M | $108M | $0 | |
| Stock Repurchased | $42M | $30M | $0 | $0 | · | |
| Net Stock Activity | $-42M | $-30M | $26M | · | · | |
| Financing Cash Flow | $-19M | $-20M | $82M | $109M | $8M | |
| Net Change in Cash | $-25M | $-91M | $-243M | $199M | $-40M | |
| Taxes Paid | $1M | $3M | $165.0K | $10M | · | |
| Free Cash Flow | $-35M | $-112M | $-121M | · | · |
Redditività 7
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Operating Margin | -87.3% | -179.7% | -181.6% | · | · | |
| Net Margin | -76.6% | -160.8% | -156.1% | · | · | |
| Pretax Margin | -75.3% | -152.8% | -156.9% | · | · | |
| EBITDA Margin | -87.3% | -179.7% | -181.6% | · | · | |
| ROA | -20.0% | -23.5% | -19.3% | · | · | |
| ROE | -26.9% | -34.8% | -26.7% | · | · | |
| ROIC | -35.1% | -42.6% | -29.6% | · | · |
Liquidità e Solvibilità 2
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Current Ratio | 5.9 | 3.4 | 7.4 | · | · | |
| Quick Ratio | 1.1 | 1.4 | 7.1 | · | · |
Efficienza 2
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Asset Turnover | 0.3 | 0.1 | 0.1 | · | · | |
| Receivables Turnover | 3.5 | 2.0 | 2.9 | · | · |
Tassi di Crescita 3
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue YoY | 38.9% | 0.38% | -81.6% | 1446.0% | -31.5% | |
| Revenue CAGR 3Y | -36.4% | 41.9% | 25.0% | · | · | |
| Revenue CAGR 5Y | 22.2% | · | · | · | · |
Valutazione (TTM) 10
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue TTM | $106M | $76M | $76M | $412M | · | |
| Net Income TTM | $-81M | $-123M | $-119M | $124M | · | |
| Market Cap | $1.97B | $1.01B | $729M | · | · | |
| P/E | -24.4 | -9.0 | -6.0 | 4.1 | · | |
| P/S | 18.5 | 13.2 | 9.6 | · | · | |
| P/B | 7.3 | 3.0 | 1.6 | · | · | |
| P / Tangible Book | 7.7 | 3.1 | 1.6 | 1.0 | · | |
| P / Cash Flow | -59.5 | -9.2 | -6.2 | · | · | |
| P / FCF | -56.9 | -9.0 | -6.0 | · | · | |
| Earnings Yield | -4.1% | -11.1% | -16.6% | 24.2% | · |
Conto Economico 14
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $5M | $2M | $3M | $28M | $49M | $27M | $31M | $16M | $19M | $10M | $17M | $17M | $7M | $36M | $402M | $3M | |
| R&D Expense | · | · | · | · | · | · | · | · | · | $32M | · | $33M | $39M | $46M | · | $37M | |
| SG&A Expense | $19M | $15M | $15M | $14M | $15M | $17M | $16M | $14M | $16M | $16M | $15M | $17M | $22M | $17M | $30M | $16M | |
| Operating Expenses | $47M | $50M | $47M | $50M | $49M | $53M | $53M | $50M | $62M | $48M | $40M | $50M | $61M | $63M | $83M | $53M | |
| Operating Income | $-42M | $-47M | $-44M | $-22M | $-674.0K | $-26M | $-22M | $-34M | $-43M | $-38M | $-23M | $-33M | $-54M | $-27M | $319M | $-50M | |
| Other Non-op | $196.0K | $120.0K | $-18.0K | $26.0K | $-621.0K | $49.0K | $-253.0K | $-37.0K | $53.0K | $19.0K | $-278.0K | $370.0K | $230.0K | $-31.0K | $-27.0K | $-98.0K | |
| Pretax Income | $-45M | $-46M | $-41M | $-18M | $2M | $-22M | $-18M | $-30M | $-38M | $-32M | $-19M | $-28M | $-49M | $-23M | $320M | $-48M | |
| Income Tax | $-273.0K | $-2M | $-270.0K | $1M | $-186.0K | $496.0K | $6M | $226.0K | $68.0K | $75.0K | $-5M | $1M | $2M | $1M | $11M | $-29.0K | |
| Net Income | $-45M | $-44M | $-41M | $-20M | $2M | $-23M | $-24M | $-30M | $-38M | $-32M | $-14M | $-29M | $-51M | $-24M | $309M | $-48M | |
| EPS (Basic) | $-0.62 | $-0.59 | $-0.55 | $-0.26 | $0.03 | $-0.30 | $-0.32 | $-0.39 | $-0.49 | $-0.42 | $-0.19 | $-0.41 | $-0.76 | $-0.36 | $4.78 | $-0.72 | |
| EPS (Diluted) | $-0.62 | $-0.59 | $-0.55 | $-0.26 | $0.03 | $-0.30 | $-0.32 | $-0.39 | $-0.49 | $-0.42 | $-0.18 | $-0.41 | $-0.76 | $-0.37 | $4.78 | $-0.72 | |
| Shares (Basic) | 72,993,313 | 74,668,790 | -150,871,069 | 75,767,778 | 75,337,168 | 75,171,020 | -152,889,276 | 76,128,531 | 76,392,593 | 76,214,833 | -135,733,099 | 70,575,773 | 67,281,028 | 66,739,308 | -129,002,888 | 66,477,016 | |
| Shares (Diluted) | 72,993,313 | 74,694,762 | -152,966,654 | 75,775,214 | 77,378,449 | 75,226,387 | -152,922,738 | 76,157,101 | 76,396,217 | 76,248,158 | -135,739,304 | 70,575,773 | 67,284,511 | 66,742,030 | -128,961,927 | 66,478,157 | |
| EBITDA | $-42M | $-47M | · | $-22M | $-674.0K | $-26M | · | $-34M | $-43M | $-38M | · | $-33M | $-54M | $-27M | · | $-50M |
Stato Patrimoniale 23
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $179M | $244M | $41M | $65M | $98M | $76M | $66M | $122M | $71M | $115M | · | $94M | $142M | $182M | · | $96M | |
| Short-term Investments | · | · | · | · | · | · | · | · | · | · | · | $201M | $198M | $159M | · | $70M | |
| Receivables | $6M | $5M | $5M | $29M | $3M | $25M | $56M | $24M | $32M | $31M | · | $67M | $49M | $67M | · | $7M | |
| Prepaid Expense | $22M | $16M | $15M | $10M | $12M | $17M | $19M | $23M | $21M | $18M | · | $12M | $31M | $19M | · | $18M | |
| Current Assets | $298M | $386M | $249M | $292M | $296M | $306M | $300M | $344M | $383M | $394M | · | $375M | $420M | $426M | · | $191M | |
| PP&E (Net) | $14M | $15M | $16M | $16M | $16M | $17M | $18M | $18M | $18M | $19M | · | $21M | $22M | $24M | · | $26M | |
| PP&E (Gross) | · | · | $36M | · | · | · | $35M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $21M | · | · | · | $18M | · | · | · | · | · | · | · | · | · | |
| Goodwill | $12M | $12M | $12M | $12M | $12M | $12M | $12M | $12M | $12M | $12M | · | $12M | $12M | $12M | · | $12M | |
| Intangibles | $998.0K | $1M | $1M | $1M | $2M | $3M | $5M | $6M | $7M | $7M | · | $8M | $7M | $8M | · | $9M | |
| Total Assets | $397M | $478M | $347M | $397M | $408M | $426M | $463M | $487M | $516M | $554M | · | $556M | $602M | $601M | · | $300M | |
| Accounts Payable | $27M | $30M | $36M | $34M | $31M | $38M | $60M | $52M | $44M | $47M | · | $68M | $70M | $59M | · | $52M | |
| Current Liabilities | $47M | $36M | $42M | $42M | $39M | $65M | $88M | $84M | $55M | $57M | · | $73M | $94M | $67M | · | $58M | |
| Capital Leases | $13M | $14M | $15M | $16M | $15M | $15M | $16M | $17M | $17M | $21M | · | $22M | $23M | $24M | · | $25M | |
| Deferred Tax | $4M | $4M | $6M | $5M | $5M | $5M | $5M | $3M | $3M | $3M | · | $2M | $2M | $2M | · | $2M | |
| Other Non-current Liabilities | $278.0K | $278.0K | $278.0K | $278.0K | $828.0K | $856.0K | $923.0K | $929.0K | $1M | $2M | · | $2M | $4M | $4M | · | $3M | |
| Total Liabilities | $317M | $315M | $78M | $77M | $74M | $101M | $124M | $120M | $109M | $116M | · | $132M | $153M | $127M | · | $121M | |
| Common Stock | $1.13B | $1.13B | $1.11B | $1.09B | $1.07B | $1.02B | $1.02B | $1.01B | $1.01B | $1.00B | · | $932M | $929M | $900M | · | $885M | |
| Retained Earnings | $-1.17B | $-1.07B | $-953M | $-886M | $-851M | $-853M | $-830M | $-798M | $-747M | $-709M | · | $-663M | $-634M | $-583M | · | $-868M | |
| AOCI | $-7M | $-7M | $-6M | $-6M | $-6M | $-6M | $-7M | $-6M | $-8M | $-8M | · | $-8M | $-8M | $-6M | · | $-7M | |
| Stockholders' Equity | $80M | $164M | $269M | $320M | $335M | $325M | $339M | $367M | $406M | $438M | $465M | $424M | $449M | $474M | $493M | $180M | |
| Liabilities + Equity | $397M | $478M | $347M | $397M | $408M | $426M | $463M | $487M | $516M | $554M | · | $556M | $602M | $601M | · | $300M | |
| Shares Outstanding | 71,412,072 | 73,102,689 | 74,638,413 | 75,139,281 | 74,846,147 | 69,584,811 | 68,964,319 | 69,584,882 | 70,831,545 | 70,677,106 | · | 67,922,559 | 67,687,384 | 64,083,770 | · | 61,694,387 |
Flusso di cassa 12
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $11M | $7M | $9M | $7M | $6M | $6M | $5M | $5M | $5M | $4M | $3M | $2M | $367.0K | $2M | $4M | $5M | |
| Amort. of Intangibles | $176.0K | $176.0K | $185.0K | $648.0K | $2M | $2M | $2M | $980.0K | $812.0K | $702.0K | $673.0K | $672.0K | $678.0K | $679.0K | $529.0K | $166.0K | |
| Operating Cash Flow | $-32M | $-46M | $-10M | $-31M | $12M | $-3M | $-42M | $-6M | $-25M | $-38M | $14M | $-43M | $-6M | $-83M | $327M | $-73M | |
| CapEx | $0 | $216.0K | $581.0K | $410.0K | $514.0K | $16.0K | $314.0K | $899.0K | $593.0K | $185.0K | $356.0K | $930.0K | $802.0K | $386.0K | $348.0K | $981.0K | |
| Investing Cash Flow | $17M | $70M | $5M | $368.0K | $9M | $12M | $-6M | $72M | $-20M | $-7M | $-1M | $-7M | $-61M | $-138M | $-22M | $-30M | |
| Stock Issued | · | · | · | · | · | · | $0 | $0 | · | · | $0 | $0 | $26M | $0 | $0 | $0 | |
| Stock Repurchased | $52M | $76M | $25M | $16M | $0 | $0 | $9M | · | · | · | $0 | · | · | · | · | · | |
| Net Stock Activity | · | $-76M | · | · | · | · | · | · | · | · | · | · | · | $0 | · | · | |
| Financing Cash Flow | $-50M | $179M | $-19M | $-2M | $1M | $1M | $-9M | $-15M | $1M | $2M | $51M | $2M | $28M | $2M | $-377.0K | $628.0K | |
| Net Change in Cash | $-65M | $203M | $-24M | $-33M | $22M | $10M | $-56M | $51M | $-44M | $-43M | $63M | $-48M | $-39M | $-219M | $305M | $-103M | |
| Taxes Paid | $863.0K | $245.0K | $107.0K | $660.0K | $196.0K | $387.0K | $3M | $106.0K | $106.0K | $0 | · | · | · | · | · | · | |
| Free Cash Flow | · | $-46M | · | · | · | $-3M | · | · | · | $-38M | · | · | · | $-84M | · | · |
Redditività 7
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -919.0% | -1956.7% | · | -80.1% | -1.4% | -94.5% | · | -213.8% | -222.9% | -376.9% | · | -201.4% | -772.8% | -76.7% | · | -1914.0% | |
| Net Margin | -980.8% | -1834.0% | · | -71.0% | 4.8% | -83.5% | · | -186.6% | -195.8% | -315.6% | · | -173.8% | -730.5% | -68.5% | · | -1818.6% | |
| Pretax Margin | -986.8% | -1925.0% | · | -66.1% | 4.4% | -81.7% | · | -185.2% | -195.5% | -314.8% | · | -167.1% | -706.9% | -64.5% | · | -1819.7% | |
| EBITDA Margin | -919.0% | -1956.7% | · | -80.1% | -1.4% | -94.5% | · | -213.8% | -222.9% | -376.9% | · | -201.4% | -772.8% | -76.7% | · | -1914.0% | |
| ROA | -11.2% | -9.8% | · | -4.4% | 0.50% | -4.6% | · | -5.7% | -6.7% | -5.5% | · | -6.7% | -17.0% | -8.1% | · | -31.9% | |
| ROE | -21.7% | -18.1% | · | -5.7% | 0.63% | -5.9% | · | -7.5% | -8.8% | -6.9% | · | -9.5% | -22.8% | -10.3% | · | -53.2% | |
| ROIC | -52.2% | -27.4% | · | -7.4% | -0.22% | -8.1% | · | -9.4% | -10.6% | -8.6% | · | -8.2% | -12.5% | -6.1% | · | -28.0% |
Liquidità e Solvibilità 2
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 6.3 | 10.8 | · | 6.9 | 7.7 | 4.7 | · | 4.1 | 7.0 | 6.9 | · | 5.1 | 4.5 | 6.3 | · | 3.3 | |
| Quick Ratio | 3.9 | 7.0 | · | 2.2 | 2.6 | 1.5 | · | 1.7 | 1.9 | 2.6 | · | 5.0 | 4.2 | 6.1 | · | 3.0 |
Efficienza 2
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.1 | 0.1 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.1 | · | 0.0 | |
| Receivables Turnover | 1.1 | 0.2 | · | 1.0 | 2.8 | 1.0 | · | 0.4 | 0.5 | 0.2 | · | 0.4 | 0.3 | 1.1 | · | 0.8 |
Valutazione (TTM) 10
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $83M | $106M | · | $119M | $111M | $72M | · | $62M | $53M | $69M | · | $62M | $51M | $46M | · | $14M | |
| Net Income TTM | $-106M | $-84M | · | $-70M | $-88M | $-122M | · | $-128M | $-149M | $-136M | · | $-152M | $-188M | $-209M | · | $-246M | |
| Market Cap | $1.87B | $1.83B | · | $1.28B | $939M | $829M | · | $873M | $603M | $744M | · | $431M | $585M | $579M | · | $379M | |
| P/E | -18.2 | -22.4 | · | -18.6 | -10.9 | -7.4 | · | -7.3 | -4.1 | -5.4 | · | -2.8 | -3.1 | -2.8 | · | -1.5 | |
| P/S | 22.4 | 17.3 | · | 10.7 | 8.5 | 11.4 | · | 14.1 | 11.4 | 10.8 | · | 7.0 | 11.5 | 12.7 | · | 26.4 | |
| P/B | 23.2 | 11.2 | · | 4.0 | 2.8 | 2.6 | · | 2.4 | 1.5 | 1.7 | · | 1.0 | 1.3 | 1.2 | · | 2.1 | |
| P / Tangible Book | 27.7 | 12.2 | · | 4.2 | 2.9 | 2.7 | · | 2.5 | 1.6 | 1.8 | · | 1.1 | 1.4 | 1.3 | · | 2.4 | |
| P / Cash Flow | · | -40.0 | · | · | · | -243.3 | · | · | · | -19.7 | · | · | · | -7.0 | · | · | |
| P / FCF | · | -39.9 | · | · | · | -242.1 | · | · | · | -19.6 | · | · | · | -6.9 | · | · | |
| Earnings Yield | -5.5% | -4.5% | · | -5.4% | -9.2% | -13.4% | · | -13.6% | -24.4% | -18.6% | · | -35.6% | -32.6% | -35.9% | · | -67.2% |
Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni
Conto Economico
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ricavi | $106M | $76M | $76M | $412M | $27M |
| Margine Operativo % | -87.3% | -179.7% | -181.6% | — | — |
| Utile netto | $-81M | $-123M | $-119M | $124M | $-212M |
| EPS Diluito | $-1.08 | $-1.62 | $-1.72 | $1.90 | $-4.61 |
Stato Patrimoniale
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Rapporto corrente | 5.9 | 3.4 | 7.4 | — | — |
| Quick Ratio | 1.1 | 1.4 | 7.1 | — | — |
Flusso di cassa
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flusso di cassa libero | $-35M | $-112M | $-121M | — | — |
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Proprietari istituzionali (13F) 218 filer · $1.5B totale · Aggiornato al 30 Giugno 2026
Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.
| Nuove posizioni | Posizioni chiuse | Aumentato | Diminuito | Variazione netta delle azioni |
|---|---|---|---|---|
| 30 (-4 vs trimestre precedente) | 29 (-2 vs trimestre precedente) | 56 (-17 vs trimestre precedente) | 68 (+9 vs trimestre precedente) | +2.6M |
Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.
| Istituzione | Valore | Azioni | % di 13F tracciati | Tipo |
|---|---|---|---|---|
| EcoR1 Capital, LLC | $600.445.942 | 22.970.388 | 39,27% | Azioni |
| Rubric Capital Management LP | $182.980.000 | 7.000.000 | 11,97% | Azioni |
| PERCEPTIVE ADVISORS LLC | $109.342.391 | 4.182.953 | 7,15% | Azioni |
| BVF INC/IL | $95.388.572 | 3.649.142 | 6,24% | Azioni |
| VANGUARD CAPITAL MANAGEMENT LLC | $40.752.208 | 1.558.998 | 2,67% | Azioni |
| Assenagon Asset Management S.A. | $32.727.986 | 1.252.027 | 2,14% | Azioni |
| Nextech Invest Ltd. | $29.118.548 | 1.113.946 | 1,90% | Azioni |
| STATE STREET CORP | $28.445.966 | 1.088.216 | 1,86% | Azioni |
| DIMENSIONAL FUND ADVISORS LP | $24.486.776 | 936.755 | 1,60% | Azioni |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $23.259.000 | 889.802 | 1,52% | Azioni |
| CITADEL ADVISORS LLC | $21.330.894 | 816.025 | 1,40% | Azioni |
| FMR LLC | $18.355.822 | 702.212 | 1,20% | Azioni |
| Prosight Management, LP | $17.629.705 | 674.434 | 1,15% | Azioni |
| GEODE CAPITAL MANAGEMENT, LLC | $16.322.460 | 624.447 | 1,07% | Azioni |
| Nextech Invest Ltd. | $16.308.169 | 1.113.946 | 1,07% | Azioni |
| Qube Research & Technologies Ltd | $15.516.443 | 593.590 | 1,01% | Azioni |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $13.332.236 | 510.032 | 0,87% | Azioni |
| Redmile Group, LLC | $12.851.836 | 491.654 | 0,84% | Azioni |
| Capricorn Fund Managers Ltd | $12.717.868 | 486.529 | 0,83% | Azioni |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $10.939.512 | 418.497 | 0,72% | Azioni |
| Hillsdale Investment Management Inc. | $10.009.581 | 382.922 | 0,65% | Azioni |
| GOLDMAN SACHS GROUP INC | $9.345.338 | 357.511 | 0,61% | Azioni |
| FIRST TRUST ADVISORS LP | $8.897.088 | 340.363 | 0,58% | Azioni |
| Granahan Investment Management, LLC | $8.787.144 | 336.157 | 0,57% | Azioni |
| Pictet Asset Management Holding SA | $7.446.189 | 308.187 | 0,49% | Azioni |
| PICTON MAHONEY ASSET MANAGEMENT | $7.092.908 | 271.343 | 0,46% | Azioni |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $5.849.243 | 223.766 | 0,38% | Azioni |
| SummitTX Capital, L.P. | $5.510.364 | 210.802 | 0,36% | Azioni |
| Man Group plc | $5.509.763 | 210.779 | 0,36% | Azioni |
| BANK OF AMERICA CORP /DE/ | $5.182.437 | 198.257 | 0,34% | Azioni |
| STATE OF WISCONSIN INVESTMENT BOARD | $4.066.835 | 155.579 | 0,27% | Azioni |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3.984.154 | 152.416 | 0,26% | Azioni |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3.960.132 | 151.497 | 0,26% | Azioni |
| KENNEDY CAPITAL MANAGEMENT LLC | $3.800.390 | 145.386 | 0,25% | Azioni |
| D. E. Shaw & Co., Inc. | $3.785.255 | 144.807 | 0,25% | Azioni |
| DIADEMA PARTNERS LP | $3.715.330 | 142.132 | 0,24% | Azioni |
| BlackRock, Inc. | $3.614.744 | 138.284 | 0,24% | Azioni |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3.408.656 | 130.400 | 0,22% | Opzione Call |
| CITIGROUP INC | $3.364.872 | 128.725 | 0,22% | Azioni |
| XTX Topco Ltd | $3.290.425 | 125.877 | 0,22% | Azioni |
| PANAGORA ASSET MANAGEMENT INC | $3.100.282 | 118.603 | 0,20% | Azioni |
| PLATINUM INVESTMENT MANAGEMENT LTD | $2.749.510 | 105.184 | 0,18% | Azioni |
| AXA Investment Managers S.A. | $2.705.745 | 158.416 | 0,18% | Azioni |
| Manatuck Hill Partners, LLC | $2.614.000 | 100.000 | 0,17% | Azioni |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2.451.932 | 93.800 | 0,16% | Opzione Put |
| KORNITZER CAPITAL MANAGEMENT INC /KS | $2.321.232 | 88.800 | 0,15% | Azioni |
| MACKENZIE FINANCIAL CORP | $2.293.654 | 87.745 | 0,15% | Azioni |
| VANGUARD GROUP INC | $2.251.979 | 85.529 | 0,15% | Azioni |
| Y-Intercept (Hong Kong) Ltd | $2.181.514 | 83.455 | 0,14% | Azioni |
| LMR Partners LLP | $2.156.550 | 82.500 | 0,14% | Azioni |
| PRINCIPAL FINANCIAL GROUP INC | $2.127.587 | 81.392 | 0,14% | Azioni |
| VANGUARD FIDUCIARY TRUST CO | $2.094.337 | 80.120 | 0,14% | Azioni |
| TEMA ETFS LLC | $2.000.422 | 75.975 | 0,13% | Azioni |
| RHUMBLINE ADVISERS | $1.962.211 | 75.066 | 0,13% | Azioni |
| Swiss National Bank | $1.939.588 | 74.200 | 0,13% | Azioni |
| MARTINGALE ASSET MANAGEMENT L P | $1.915.592 | 73.282 | 0,13% | Azioni |
| TWO SIGMA INVESTMENTS, LP | $1.878.786 | 71.874 | 0,12% | Azioni |
| Dana Investment Advisors, Inc. | $1.873.192 | 71.660 | 0,12% | Azioni |
| CREDIT AGRICOLE S A | $1.855.940 | 71.000 | 0,12% | Azioni |
| Fisher Asset Management, LLC | $1.850.057 | 70.775 | 0,12% | Azioni |
| SEGALL BRYANT & HAMILL, LLC | $1.747.093 | 66.836 | 0,11% | Azioni |
| Verdad Advisers, LP | $1.743.224 | 66.688 | 0,11% | Azioni |
| Susquehanna Portfolio Strategies, LLC | $1.705.583 | 65.248 | 0,11% | Azioni |
| Campbell & CO Investment Adviser LLC | $1.591.246 | 60.874 | 0,10% | Azioni |
| ALLIANCEBERNSTEIN L.P. | $1.399.636 | 55.896 | 0,09% | Azioni |
| CITADEL ADVISORS LLC | $1.364.508 | 52.200 | 0,09% | Opzione Call |
| Virtus Investment Advisers, LLC | $1.328.566 | 50.825 | 0,09% | Azioni |
| ENVESTNET ASSET MANAGEMENT INC | $1.272.365 | 48.675 | 0,08% | Azioni |
| Quantinno Capital Management LP | $1.245.362 | 47.642 | 0,08% | Azioni |
| WELLS FARGO & COMPANY/MN | $1.122.164 | 42.929 | 0,07% | Azioni |
| VICTORY CAPITAL MANAGEMENT INC | $1.111.577 | 42.524 | 0,07% | Azioni |
| Bank of New York Mellon Corp | $1.076.785 | 41.193 | 0,07% | Azioni |
| MARSHALL WACE, LLP | $1.070.380 | 40.948 | 0,07% | Azioni |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | $1.033.419 | 39.534 | 0,07% | Azioni |
| Aquilo Capital Management, LLC | $1.006.181 | 84.482 | 0,07% | Azioni |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $965.141 | 36.922 | 0,06% | Azioni |
| TUDOR INVESTMENT CORP ET AL | $953.352 | 36.471 | 0,06% | Azioni |
| HighTower Advisors, LLC | $943.654 | 36.100 | 0,06% | Azioni |
| Persistent Asset Partners Ltd | $939.341 | 35.935 | 0,06% | Azioni |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $936.221 | 37.389 | 0,06% | Azioni |
| WELLINGTON MANAGEMENT GROUP LLP | $904.653 | 34.608 | 0,06% | Azioni |
| HighVista Strategies LLC | $889.100 | 34.013 | 0,06% | Azioni |
| COMMONWEALTH EQUITY SERVICES, LLC | $837.838 | 32.052 | 0,05% | Azioni |
| TWO SIGMA ADVISERS, LP | $827.157 | 31.415 | 0,05% | Azioni |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $807.360 | 30.886 | 0,05% | Azioni |
| SBI Okasan Asset Management Co.Ltd. | $771.200 | 32.000 | 0,05% | Azioni |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $735.529 | 27.935 | 0,05% | Azioni |
| MetLife Investment Management, LLC | $728.888 | 27.884 | 0,05% | Azioni |
| JOURNEY STRATEGIC WEALTH LLC | $722.304 | 28.846 | 0,05% | Azioni |
| STRS OHIO | $692.710 | 26.500 | 0,05% | Azioni |
| VANGUARD ASSET MANAGEMENT, Ltd | $686.933 | 26.279 | 0,04% | Azioni |
| Brevan Howard Capital Management LP | $678.490 | 25.956 | 0,04% | Azioni |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $657.735 | 25.162 | 0,04% | Azioni |
| RITHOLTZ WEALTH MANAGEMENT | $633.712 | 24.243 | 0,04% | Azioni |
| BNP PARIBAS FINANCIAL MARKETS | $607.206 | 23.229 | 0,04% | Azioni |
| Duncan Williams Asset Management, LLC | $577.563 | 22.095 | 0,04% | Azioni |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $564.049 | 21.578 | 0,04% | Azioni |
| BARCLAYS PLC | $524.577 | 20.068 | 0,03% | Azioni |
| SIMPLEX TRADING, LLC | $507.926 | 19.431 | 0,03% | Azioni |
| Invesco Ltd. | $491.720 | 18.811 | 0,03% | Azioni |
Insider aziendali 28 insider · 12 dirigenti · 17 direttori
| Insider | Ruolo | Ultima attività | Azioni possedute | Acquisti 12m | Vendite 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Kenneth Galbraith | Chair & CEO | 12 Gennaio 2026 A | 226.842 | 0 | 4 | $-3.337.929 |
| Kristin Stafford | EVP, Chief Financial Officer | 06 Aprile 2026 A | — | 0 | 0 | $0 |
| Christopher Astle | SVP & Chief Financial Officer | 05 Gennaio 2024 A | 6.503 | 0 | 0 | $0 |
| Neil A Klompas | President & COO | 10 Marzo 2023 M | 17.032 | 0 | 0 | $0 |
| Mark Hollywood | EVP & Chief Operating Officer | 06 Luglio 2026 A | 133.852 | 0 | 1 | $-138.740 |
| Paul R Schneider | EVP, General Counsel | 13 Maggio 2026 A | — | 0 | 0 | $0 |
| Adam Schayowitz | EVP, Head of Research & Development | 09 Aprile 2026 A | — | 0 | 0 | $0 |
| Scott Platshon | EVP, Chief Business Officer | 09 Aprile 2026 A | — | 0 | 0 | $0 |
| Paul Andrew Moore | Chief Scientific Officer | 12 Gennaio 2026 A | 48.497 | 0 | 3 | $-721.486 |
| Jeffrey T L Smith | EVP & Chief Medical Officer | 12 Gennaio 2026 M | 26.708 | 0 | 2 | $-475.562 |
| Leone D Patterson | EVP, Chief Bus & Fin Officer | 06 Gennaio 2026 A | 459 | 0 | 0 | $0 |
| Neil Josephson | Chief Medical Officer | 10 Novembre 2022 M | 14.449 | 0 | 0 | $0 |
| Gregory A. Ciongoli | Direttore | 12 Gennaio 2026 A | 488.500 | 0 | 0 | $0 |
| Alessandra Cesano | Direttore | 12 Gennaio 2026 A | — | 0 | 0 | $0 |
| Carlos Campoy | Direttore | 12 Gennaio 2026 A | — | 0 | 0 | $0 |
| Robert E Landry | Direttore | 12 Gennaio 2026 A | — | 0 | 0 | $0 |
| Kelvin Neu | Direttore | 12 Gennaio 2026 A | — | 0 | 0 | $0 |
| Susan Mahony | Direttore | 12 Gennaio 2026 A | — | 0 | 0 | $0 |
| Brian N Cherry | Direttore | 12 Gennaio 2026 A | — | 0 | 0 | $0 |
| EcoR1 Capital, LLC | Direttore | 17 Gennaio 2025 P | 15.720.161 | 0 | 0 | $0 |
| Nancy Davidson | Direttore | 10 Dicembre 2024 A | — | 0 | 0 | $0 |
| Neil Gallagher | Direttore | 10 Dicembre 2024 A | — | 0 | 0 | $0 |
| Derek John Michael Miller | Direttore | 10 Dicembre 2024 A | — | 0 | 0 | $0 |
| Troy Cox | Direttore | 10 Dicembre 2024 A | — | 0 | 0 | $0 |
| Kenneth J. Hillan | Direttore | 07 Dicembre 2023 A | — | 0 | 0 | $0 |
| Hollings Renton | Direttore | 07 Dicembre 2023 A | — | 0 | 0 | $0 |
| Natalie Sacks | Direttore | 21 Dicembre 2022 A | — | 0 | 0 | $0 |
| Lota S. Zoth | Direttore | 21 Dicembre 2022 A | — | 0 | 0 | $0 |
Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato
Attivisti e proprietari del 5%+ 2 partecipazioni
Investitori che hanno depositato SEC Schedule 13D — proprietà effettiva superiore al 5% con l'intento di influenzare l'emittente (partecipazioni attiviste, campagne per il consiglio di amministrazione, M&A). Ogni riga mostra lo stato più recente noto della posizione di quel depositante.
| Depositante | Depositato | Partecipazione | Stato | Scopo | Deposito |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC, Oleg Nodelman, EcoR1 Capital Fund Qualified, L.P. ×8 depositi | 19 Novembre 2025 | 30,70% | Modifica | Campagna per il consiglio di amministrazione | SEC |
| All Blue Falcons FZE, Daniel Edward Llewellen Cookson ×2 depositi | 28 Dicembre 2022 | — | Deposito iniziale | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Proprietà ETF Posseduti da 41 ETF
Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.
| Fondo | Peso | Unità | Aggiornato al | Fonte |
|---|---|---|---|---|
| CANC · Tema ETF Trust | 1,51% | 105.615 NS | 31 Maggio 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,80% | 10.832 NS | 30 Aprile 2026 | N-PORT |
| FYC · First Trust Exchange-Traded AlphaDE… | 0,49% | 186.247 NS | 30 Aprile 2026 | N-PORT |
| FYX · First Trust Exchange-Traded AlphaDE… | 0,25% | 110.902 NS | 30 Aprile 2026 | N-PORT |
| FSCC · Federated Hermes ETF Trust | 0,15% | 16.669 NS | 31 Maggio 2026 | N-PORT |
| SMMV · iShares Trust | 0,13% | 16.160 SH | 08 Agosto 2026 | Giornaliero |
| IBB · iShares Trust | 0,13% | 517.328 SH | 08 Agosto 2026 | Giornaliero |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,12% | 14.789 SH | 08 Agosto 2026 | Giornaliero |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,12% | 3.975 SH | 08 Agosto 2026 | Giornaliero |
| VFMO · VANGUARD WELLINGTON FUND | 0,10% | 74.514 SH | 08 Agosto 2026 | Giornaliero |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,10% | 17.393 NS | 30 Aprile 2026 | N-PORT |
| BIB · ProShares Trust | 0,09% | 2.766 NS | 31 Maggio 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,07% | 50.443 SH | 08 Agosto 2026 | Giornaliero |
| IWO · iShares Trust | 0,07% | 423.822 SH | 08 Agosto 2026 | Giornaliero |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,06% | 67.771 SH | 08 Agosto 2026 | Giornaliero |
| RSSL · Global X Funds | 0,04% | 21.639 NS | 30 Aprile 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,04% | 270.692 SH | 08 Agosto 2026 | Giornaliero |
| DFAS · Dimensional ETF Trust | 0,04% | 189.866 NS | 30 Aprile 2026 | N-PORT |
| IWM · iShares Trust | 0,03% | 1.183.337 SH | 08 Agosto 2026 | Giornaliero |
| ITWO · ProShares Trust | 0,03% | 2.345 NS | 31 Maggio 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,03% | 10.887 NS | 31 Maggio 2026 | N-PORT |
| ISCV · iShares Trust | 0,02% | 5.753 SH | 08 Agosto 2026 | Giornaliero |
| UWM · ProShares Trust | 0,02% | 1.834 NS | 31 Maggio 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,02% | 16.794 NS | 30 Aprile 2026 | N-PORT |
| ISCB · iShares Trust | 0,02% | 1.999 SH | 08 Agosto 2026 | Giornaliero |
| ISCG · iShares Trust | 0,01% | 5.891 SH | 08 Agosto 2026 | Giornaliero |
| URTY · ProShares Trust | 0,01% | 1.855 NS | 31 Maggio 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 3.008 SH | 08 Agosto 2026 | Giornaliero |
| VHT · VANGUARD WORLD FUND | 0,01% | 110.298 SH | 08 Agosto 2026 | Giornaliero |
| TILT · FlexShares Trust | 0,01% | 5.236 NS | 30 Aprile 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 1.925 NS | 31 Maggio 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 26.839 NS | 31 Maggio 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 47 NS | 31 Maggio 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 5.213 NS | 30 Aprile 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 72.902 NS | 30 Aprile 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 12.951 NS | 30 Aprile 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 14.256 SH | 08 Agosto 2026 | Giornaliero |
| DFUS · Dimensional ETF Trust | 0,00% | 8.364 NS | 30 Aprile 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 130 NS | 30 Aprile 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1.508.613 SH | 08 Agosto 2026 | Giornaliero |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 4.085 SH | 08 Agosto 2026 | Giornaliero |