| BAKER BROS. ADVISORS LP |
$37,335,293 |
5,072,730 |
14.70% |
주식
|
| 5AM Venture Management, LLC |
$29,854,949 |
4,056,379 |
11.76% |
주식
|
| MPM ASSET MANAGEMENT LLC |
$25,410,160 |
4,381,062 |
10.01% |
주식
|
| BlackRock, Inc. |
$19,013,332 |
2,583,333 |
7.49% |
주식
|
| VANGUARD GROUP INC |
$16,781,689 |
1,632,460 |
6.61% |
주식
|
| Merck & Co., Inc. |
$12,804,692 |
1,739,768 |
5.04% |
주식
|
| StepStone Group LP |
$9,607,316 |
761,277 |
3.78% |
주식
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$9,344,506 |
1,269,634 |
3.68% |
주식
|
| MPM BIOIMPACT LLC |
$9,222,470 |
1,253,053 |
3.63% |
주식
|
| TCG Crossover Management, LLC |
$7,803,293 |
1,060,230 |
3.07% |
주식
|
| WELLINGTON MANAGEMENT GROUP LLP |
$7,024,524 |
954,419 |
2.77% |
주식
|
| MILLENNIUM MANAGEMENT LLC |
$5,622,738 |
763,959 |
2.21% |
주식
|
| GEODE CAPITAL MANAGEMENT, LLC |
$5,281,368 |
717,430 |
2.08% |
주식
|
| AQR CAPITAL MANAGEMENT LLC |
$5,148,591 |
699,537 |
2.03% |
주식
|
| STATE STREET CORP |
$4,391,543 |
596,677 |
1.73% |
주식
|
| JPMORGAN CHASE & CO |
$3,827,683 |
496,457 |
1.51% |
주식
|
| CITADEL ADVISORS LLC |
$2,902,217 |
394,323 |
1.14% |
주식
|
| DIMENSIONAL FUND ADVISORS LP |
$2,769,577 |
376,136 |
1.09% |
주식
|
| NORTHERN TRUST CORP |
$2,281,173 |
309,942 |
0.90% |
주식
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$2,233,458 |
303,459 |
0.88% |
주식
|
| Nantahala Capital Management, LLC |
$2,212,232 |
300,575 |
0.87% |
주식
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$1,870,397 |
254,130 |
0.74% |
주식
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$1,450,921 |
197,136 |
0.57% |
주식
|
| Longaeva Partners L.P. |
$1,436,944 |
195,237 |
0.57% |
주식
|
| MORGAN STANLEY |
$1,410,544 |
191,650 |
0.56% |
주식
|
| RENAISSANCE TECHNOLOGIES LLC |
$1,405,760 |
191,000 |
0.55% |
주식
|
| Quantinno Capital Management LP |
$1,389,855 |
188,839 |
0.55% |
주식
|
| Lynx1 Capital Management LP |
$1,314,540 |
178,606 |
0.52% |
주식
|
| GOLDMAN SACHS GROUP INC |
$1,305,247 |
177,343 |
0.51% |
주식
|
| VANGUARD FIDUCIARY TRUST CO |
$1,233,875 |
167,646 |
0.49% |
주식
|
| Woodline Partners LP |
$1,071,616 |
145,600 |
0.42% |
주식
|
| Trexquant Investment LP |
$1,031,452 |
140,143 |
0.41% |
주식
|
| MOORE CAPITAL MANAGEMENT, LP |
$772,800 |
105,000 |
0.30% |
주식
|
| Cubist Systematic Strategies, LLC |
$711,521 |
122,676 |
0.28% |
주식
|
| XTX Topco Ltd |
$701,680 |
95,337 |
0.28% |
주식
|
| BNP PARIBAS FINANCIAL MARKETS |
$699,524 |
95,044 |
0.28% |
주식
|
| Allspring Global Investments Holdings, LLC |
$688,440 |
93,538 |
0.27% |
주식
|
| ROYCE & ASSOCIATES LP |
$610,159 |
82,902 |
0.24% |
주식
|
| AMERICAN CENTURY COMPANIES INC |
$586,599 |
79,701 |
0.23% |
주식
|
| Bank of New York Mellon Corp |
$581,955 |
79,070 |
0.23% |
주식
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$533,747 |
72,520 |
0.21% |
주식
|
| AMERIPRISE FINANCIAL INC |
$518,107 |
70,395 |
0.20% |
주식
|
| Qube Research & Technologies Ltd |
$448,018 |
60,872 |
0.18% |
주식
|
| CANTOR FITZGERALD, L. P. |
$441,600 |
60,000 |
0.17% |
주식
|
| BANK OF AMERICA CORP /DE/ |
$426,343 |
57,927 |
0.17% |
주식
|
| Nuveen, LLC |
$417,879 |
56,777 |
0.16% |
주식
|
| ALLIANCEBERNSTEIN L.P. |
$399,297 |
31,640 |
0.16% |
주식
|
| Susquehanna Portfolio Strategies, LLC |
$398,272 |
54,113 |
0.16% |
주식
|
| TD Asset Management Inc |
$394,408 |
53,588 |
0.16% |
주식
|
| ExodusPoint Capital Management, LP |
$388,365 |
52,767 |
0.15% |
주식
|
| Nan Fung Group Holdings Ltd |
$361,244 |
49,082 |
0.14% |
주식
|
| TWO SIGMA INVESTMENTS, LP |
$341,519 |
46,402 |
0.13% |
주식
|
| Invesco Ltd. |
$326,372 |
44,344 |
0.13% |
주식
|
| UBS Group AG |
$305,911 |
41,564 |
0.12% |
주식
|
| GREAT LAKES ADVISORS, LLC |
$283,441 |
38,511 |
0.11% |
주식
|
| MARTINGALE ASSET MANAGEMENT L P |
$281,616 |
38,263 |
0.11% |
주식
|
| HSBC HOLDINGS PLC |
$278,266 |
36,470 |
0.11% |
주식
|
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO |
$276,015 |
37,502 |
0.11% |
주식
|
| RHUMBLINE ADVISERS |
$270,421 |
36,743 |
0.11% |
주식
|
| Y-Intercept (Hong Kong) Ltd |
$255,296 |
34,687 |
0.10% |
주식
|
| Brevan Howard Capital Management LP |
$250,012 |
33,969 |
0.10% |
주식
|
| Graham Capital Management, L.P. |
$246,244 |
33,457 |
0.10% |
주식
|
| D. E. Shaw & Co., Inc. |
$238,442 |
32,397 |
0.09% |
주식
|
| Odyssean, LLC |
$230,405 |
31,305 |
0.09% |
주식
|
| Corton Capital Inc. |
$225,324 |
38,849 |
0.09% |
주식
|
| IEQ CAPITAL, LLC |
$218,437 |
29,679 |
0.09% |
주식
|
| BARCLAYS PLC |
$210,495 |
28,600 |
0.08% |
주식
|
| Point72 Asset Management, L.P. |
$209,760 |
28,500 |
0.08% |
주식
|
| China Universal Asset Management Co., Ltd. |
$204,446 |
27,778 |
0.08% |
주식
|
| Verdad Advisers, LP |
$202,400 |
27,500 |
0.08% |
주식
|
| DEUTSCHE BANK AG\ |
$195,452 |
26,556 |
0.08% |
주식
|
| Voleon Capital Management LP |
$186,385 |
25,324 |
0.07% |
주식
|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
$184,000 |
25,000 |
0.07% |
주식
|
| WELLS FARGO & COMPANY/MN |
$183,279 |
24,902 |
0.07% |
주식
|
| Jump Financial, LLC |
$177,170 |
24,072 |
0.07% |
주식
|
| Inscription Capital, LLC |
$176,206 |
23,941 |
0.07% |
주식
|
| Russell Investments Group, Ltd. |
$172,591 |
23,450 |
0.07% |
주식
|
| AlphaQuest LLC |
$160,666 |
15,629 |
0.06% |
주식
|
| Mariner, LLC |
$159,779 |
21,707 |
0.06% |
주식
|
| MERCER GLOBAL ADVISORS INC /ADV |
$152,006 |
20,653 |
0.06% |
주식
|
| MetLife Investment Management, LLC |
$129,941 |
17,655 |
0.05% |
주식
|
| ADAR1 Capital Management, LLC |
$114,080 |
15,500 |
0.04% |
주식
|
| PANAGORA ASSET MANAGEMENT INC |
$114,028 |
15,493 |
0.04% |
주식
|
| CITIGROUP INC |
$108,854 |
14,790 |
0.04% |
주식
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$99,735 |
13,551 |
0.04% |
주식
|
| Cerity Partners LLC |
$99,442 |
13,511 |
0.04% |
주식
|
| Quadrature Capital Ltd |
$97,572 |
13,257 |
0.04% |
주식
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$88,364 |
12,769 |
0.03% |
주식
|
| CWM, LLC |
$85,665 |
6,788 |
0.03% |
주식
|
| Police & Firemen's Retirement System of New Jersey |
$69,707 |
9,471 |
0.03% |
주식
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$65,335 |
8,877 |
0.03% |
주식
|
| Vanguard Global Advisers, LLC |
$64,856 |
8,812 |
0.03% |
주식
|
| State of Wyoming |
$36,903 |
5,014 |
0.01% |
주식
|
| Arax Advisory Partners |
$32,958 |
4,478 |
0.01% |
주식
|
| Versant Capital Management, Inc |
$26,702 |
4,205 |
0.01% |
주식
|
| STRS OHIO |
$23,552 |
3,200 |
0.01% |
주식
|
| NISA INVESTMENT ADVISORS, LLC |
$21,874 |
2,972 |
0.01% |
주식
|
| Tower Research Capital LLC (TRC) |
$21,462 |
2,916 |
0.01% |
주식
|
| Zurcher Kantonalbank (Zurich Cantonalbank) |
$19,784 |
2,688 |
0.01% |
주식
|
| Legal & General Group Plc |
$18,807 |
2,557 |
0.01% |
주식
|
| Ameritas Investment Partners, Inc. |
$17,789 |
2,417 |
0.01% |
주식
|
| FMR LLC |
$15,962 |
2,169 |
0.01% |
주식
|
| FEDERATED HERMES, INC. |
$14,484 |
1,968 |
0.01% |
주식
|
| Mirae Asset Global Investments Co., Ltd. |
$12,777 |
1,736 |
0.01% |
주식
|
| PNC Financial Services Group, Inc. |
$8,354 |
1,135 |
0.00% |
주식
|
| Point72 (DIFC) Ltd |
$7,876 |
1,358 |
0.00% |
주식
|
| ROYAL BANK OF CANADA |
$6,000 |
882 |
0.00% |
주식
|
| GF FUND MANAGEMENT CO. LTD. |
$5,976 |
812 |
0.00% |
주식
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$5,490 |
435 |
0.00% |
주식
|
| Allworth Financial LP |
$4,762 |
647 |
0.00% |
주식
|
| EverSource Wealth Advisors, LLC |
$4,724 |
642 |
0.00% |
주식
|
| Essential Partners LLC |
$4,394 |
597 |
0.00% |
주식
|
| Sterling Capital Management LLC |
$4,364 |
593 |
0.00% |
주식
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$3,992 |
542,316 |
0.00% |
주식
|
| GAMMA Investing LLC |
$3,864 |
525 |
0.00% |
주식
|
| ACADIAN ASSET MANAGEMENT LLC |
$2,945 |
400,862 |
0.00% |
주식
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$2,937 |
399 |
0.00% |
주식
|
| True Wealth Design, LLC |
$2,260 |
307 |
0.00% |
주식
|
| ROTHSCHILD INVESTMENT LLC |
$2,009 |
273 |
0.00% |
주식
|
| Optiver Holding B.V. |
$1,722 |
234 |
0.00% |
주식
|
| Private Wealth Management Group, LLC |
$1,561 |
212 |
0.00% |
주식
|
| OSAIC HOLDINGS, INC. |
$1,435 |
195 |
0.00% |
주식
|
| MassMutual Private Wealth & Trust, FSB |
$1,369 |
186 |
0.00% |
주식
|
| IFP Advisors, Inc |
$1,259 |
171 |
0.00% |
주식
|
| Farther Finance Advisors, LLC |
$1,054 |
143 |
0.00% |
주식
|
| Clearstead Advisors, LLC |
$1,038 |
141 |
0.00% |
주식
|
| Cornerstone Financial Management LLC |
$670 |
91 |
0.00% |
주식
|
| GSA CAPITAL PARTNERS LLP |
$648 |
88,005 |
0.00% |
주식
|
| ZIONS BANCORPORATION, NATIONAL ASSOCIATION /UT/ |
$640 |
87 |
0.00% |
주식
|
| SJS Investment Consulting Inc. |
$523 |
71 |
0.00% |
주식
|
| Caitong International Asset Management Co., Ltd |
$339 |
46 |
0.00% |
주식
|
| Wealth Enhancement Trust Services, Inc. |
$316 |
43 |
0.00% |
주식
|
| HARBOR CAPITAL ADVISORS, INC. |
$245 |
33,351 |
0.00% |
주식
|
| Quarry LP |
$184 |
25 |
0.00% |
주식
|
| SBI Securities Co., Ltd. |
$15 |
2 |
0.00% |
주식
|