NAMS — الملاك المؤسسيون (13F)
المؤسسات التي تبلغ عن حيازتها لهذا السهم في نموذج SEC 13F ربع السنوي الخاص بها. المراكز الطويلة فقط؛ قد يظهر مقدم واحد مرتين لأرجل خيارات منفصلة. الأرجل الكبيرة المتعاكسة من خيارات البيع/الشراء تعكس عادةً صناعة السوق أو المخزون المتحوط، وليس القناعة الاتجاهية.
| مؤسسة | القيمة | الأسهم | % من 13F المتتبعة | النوع |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $613032889 | 18088902 | 15,23% | الأسهم |
| Capital World Investors | $414493577 | 12230557 | 10,30% | الأسهم |
| FMR LLC | $350411179 | 10339663 | 8,70% | الأسهم |
| RA CAPITAL MANAGEMENT, L.P. | $323655973 | 9550191 | 8,04% | الأسهم |
| FCPM III SERVICES B.V. | $287738063 | 8490353 | 7,15% | الأسهم |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $144533699 | 4264789 | 3,59% | الأسهم |
| VIKING GLOBAL INVESTORS LP | $142458886 | 4203567 | 3,54% | الأسهم |
| Bain Capital Life Sciences Investors, LLC | $129004522 | 3806566 | 3,20% | الأسهم |
| MAVERICK CAPITAL LTD | $110745810 | 3267802 | 2,75% | الأسهم |
| Medicxi Ventures Management (Jersey) Ltd | $74850776 | 2208639 | 1,86% | الأسهم |
| JANUS HENDERSON GROUP PLC | $72253603 | 2258984 | 1,79% | الأسهم |
| JENNISON ASSOCIATES LLC | $71246471 | 2102286 | 1,77% | الأسهم |
| Orbis Allan Gray Ltd | $59227079 | 1747627 | 1,47% | الأسهم |
| Polar Capital Holdings Plc | $58443915 | 1724518 | 1,45% | الأسهم |
| Capital International Investors | $58409246 | 1723495 | 1,45% | الأسهم |
| GOLDMAN SACHS GROUP INC | $52357034 | 1544911 | 1,30% | الأسهم |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $52071036 | 1536472 | 1,29% | الأسهم |
| Castle Hook Partners LP | $46463359 | 1371005 | 1,15% | الأسهم |
| AMERIPRISE FINANCIAL INC | $42482886 | 1253549 | 1,06% | الأسهم |
| ALLIANCEBERNSTEIN L.P. | $40330679 | 1259940 | 1,00% | الأسهم |
| JPMORGAN CHASE & CO | $38373185 | 1132955 | 0,95% | الأسهم |
| Aberdeen Group plc | $37373384 | 1102785 | 0,93% | الأسهم |
| BlackRock, Inc. | $36050487 | 1063750 | 0,90% | الأسهم |
| FRANKLIN RESOURCES INC | $33683835 | 993917 | 0,84% | الأسهم |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $26472835 | 781140 | 0,66% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $25564142 | 754327 | 0,63% | الأسهم |
| Woodline Partners LP | $25501852 | 752489 | 0,63% | الأسهم |
| BANK OF AMERICA CORP /DE/ | $24925518 | 735483 | 0,62% | الأسهم |
| TimesSquare Capital Management, LLC | $24071136 | 751988 | 0,60% | الأسهم |
| AMERICAN CENTURY COMPANIES INC | $23208343 | 684813 | 0,58% | الأسهم |
| CITADEL ADVISORS LLC | $21886331 | 645805 | 0,54% | الأسهم |
| Jefferies Financial Group Inc. | $20334000 | 600000 | 0,51% | عقد خيار البيع |
| Rock Springs Capital Management LP | $19749194 | 582744 | 0,49% | الأسهم |
| First Turn Management, LLC | $19740823 | 582497 | 0,49% | الأسهم |
| MORGAN STANLEY | $19514724 | 575825 | 0,48% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $19269854 | 568600 | 0,48% | عقد خيار البيع |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $18639500 | 550000 | 0,46% | الأسهم |
| Artia Global Partners LP | $17078391 | 503936 | 0,42% | الأسهم |
| MILLENNIUM MANAGEMENT LLC | $16999698 | 501614 | 0,42% | الأسهم |
| PERCEPTIVE ADVISORS LLC | $16945000 | 500000 | 0,42% | عقد خيار البيع |
| Cormorant Asset Management, LP | $16945000 | 500000 | 0,42% | الأسهم |
| JANE STREET GROUP, LLC | $16071858 | 474236 | 0,40% | الأسهم |
| KENNEDY CAPITAL MANAGEMENT LLC | $14280365 | 421374 | 0,35% | الأسهم |
| Bank of New York Mellon Corp | $11973270 | 353298 | 0,30% | الأسهم |
| UBS Group AG | $11660363 | 344065 | 0,29% | الأسهم |
| Slate Path Capital LP | $10810910 | 319000 | 0,27% | الأسهم |
| ExodusPoint Capital Management, LP | $10313879 | 304334 | 0,26% | الأسهم |
| Eversept Partners, LP | $9335712 | 275471 | 0,23% | الأسهم |
| Affinity Asset Advisors, LLC | $9319750 | 275000 | 0,23% | الأسهم |
| SEB Asset Management AB | $9240226 | 272654 | 0,23% | الأسهم |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $9131973 | 285285 | 0,23% | الأسهم |
| Atle Fund Management AB | $8433458 | 248848 | 0,21% | الأسهم |
| GILDER GAGNON HOWE & CO LLC | $7593732 | 224070 | 0,19% | الأسهم |
| WELLINGTON MANAGEMENT GROUP LLP | $7413404 | 218749 | 0,18% | الأسهم |
| LMR Partners LLP | $7269405 | 214500 | 0,18% | عقد خيار البيع |
| Ensign Peak Advisors, Inc | $7199015 | 212423 | 0,18% | الأسهم |
| ArrowMark Colorado Holdings LLC | $7179359 | 211843 | 0,18% | الأسهم |
| DEUTSCHE BANK AG\ | $6775662 | 199931 | 0,17% | الأسهم |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $6156932 | 181674 | 0,15% | الأسهم |
| VANGUARD GROUP INC | $6067297 | 172956 | 0,15% | الأسهم |
| Decheng Capital LLC | $5994700 | 176887 | 0,15% | الأسهم |
| VICTORY CAPITAL MANAGEMENT INC | $5851549 | 172663 | 0,15% | الأسهم |
| PEREGRINE CAPITAL MANAGEMENT LLC | $5743948 | 169488 | 0,14% | الأسهم |
| Point72 Asset Management, L.P. | $5724055 | 168901 | 0,14% | الأسهم |
| AXA Investment Managers S.A. | $5596480 | 196782 | 0,14% | الأسهم |
| Mizuho Markets Cayman LP | $5101767 | 150539 | 0,13% | الأسهم |
| TD Asset Management Inc | $5029276 | 148400 | 0,12% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5015720 | 148000 | 0,12% | عقد خيار الشراء |
| XTX Topco Ltd | $4914321 | 145008 | 0,12% | الأسهم |
| Jump Financial, LLC | $4897512 | 144512 | 0,12% | الأسهم |
| DCF Advisers, LLC | $4778490 | 141000 | 0,12% | الأسهم |
| KORNITZER CAPITAL MANAGEMENT INC /KS | $4742329 | 139933 | 0,12% | الأسهم |
| Cutter Capital Management, LP | $4526981 | 221152 | 0,11% | الأسهم |
| Jefferies Financial Group Inc. | $4159252 | 122728 | 0,10% | الأسهم |
| BOOTHBAY FUND MANAGEMENT, LLC | $4107468 | 121200 | 0,10% | عقد خيار البيع |
| Swiss National Bank | $4104079 | 121100 | 0,10% | الأسهم |
| D. E. Shaw & Co., Inc. | $4085812 | 120561 | 0,10% | الأسهم |
| ADAR1 Capital Management, LLC | $4020133 | 118623 | 0,10% | الأسهم |
| ALPS ADVISORS INC | $4003934 | 118145 | 0,10% | الأسهم |
| STATE STREET CORP | $3904636 | 115215 | 0,10% | الأسهم |
| Walleye Capital LLC | $3789546 | 111819 | 0,09% | الأسهم |
| GEODE CAPITAL MANAGEMENT, LLC | $3562287 | 105169 | 0,09% | الأسهم |
| Swedbank AB | $3527949 | 104100 | 0,09% | الأسهم |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $3261302 | 96232 | 0,08% | الأسهم |
| NORTHERN TRUST CORP | $3184677 | 93971 | 0,08% | الأسهم |
| Caption Management, LLC | $3124658 | 92200 | 0,08% | عقد خيار البيع |
| Squarepoint Ops LLC | $3118761 | 92026 | 0,08% | الأسهم |
| Moody Aldrich Partners LLC | $3071010 | 90617 | 0,08% | الأسهم |
| Schonfeld Strategic Advisors LLC | $3042135 | 89765 | 0,08% | الأسهم |
| Bellevue Group AG | $2948227 | 86994 | 0,07% | الأسهم |
| ALGERT GLOBAL LLC | $2756613 | 81340 | 0,07% | الأسهم |
| Man Group plc | $2739396 | 80832 | 0,07% | الأسهم |
| TUDOR INVESTMENT CORP ET AL | $2692899 | 79460 | 0,07% | الأسهم |
| Y-Intercept (Hong Kong) Ltd | $2648029 | 78136 | 0,07% | الأسهم |
| STEMPOINT CAPITAL LP | $2629491 | 77589 | 0,07% | الأسهم |
| Headlands Technologies LLC | $2451433 | 72335 | 0,06% | الأسهم |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2284796 | 67418 | 0,06% | الأسهم |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $2145169 | 63298 | 0,05% | الأسهم |
| FOX RUN MANAGEMENT, L.L.C. | $2015675 | 59477 | 0,05% | الأسهم |
| Russell Investments Group, Ltd. | $1989578 | 58707 | 0,05% | الأسهم |
| China Universal Asset Management Co., Ltd. | $1647223 | 48605 | 0,04% | الأسهم |
| Qube Research & Technologies Ltd | $1595880 | 47090 | 0,04% | الأسهم |
| FRED ALGER MANAGEMENT, LLC | $1528947 | 45115 | 0,04% | الأسهم |
| Palo Alto Investors LP | $1503327 | 44359 | 0,04% | الأسهم |
| Knights of Columbus Asset Advisors LLC | $1484382 | 43800 | 0,04% | الأسهم |
| FIRST TRUST ADVISORS LP | $1460930 | 43108 | 0,04% | الأسهم |
| VANGUARD ASSET MANAGEMENT, Ltd | $1437682 | 42422 | 0,04% | الأسهم |
| Fieldview Capital Management, LLC | $1418025 | 41842 | 0,04% | الأسهم |
| SEI INVESTMENTS CO | $1385017 | 40868 | 0,03% | الأسهم |
| Legal & General Group Plc | $1333336 | 39343 | 0,03% | الأسهم |
| CITADEL ADVISORS LLC | $1301376 | 38400 | 0,03% | عقد خيار الشراء |
| Ishara Investments LP | $1250541 | 36900 | 0,03% | الأسهم |
| BOOTHBAY FUND MANAGEMENT, LLC | $1211771 | 35756 | 0,03% | الأسهم |
| BNP PARIBAS FINANCIAL MARKETS | $1210212 | 35710 | 0,03% | الأسهم |
| LMR Partners LLP | $1155649 | 34100 | 0,03% | عقد خيار الشراء |
| STATE OF WISCONSIN INVESTMENT BOARD | $1123759 | 33159 | 0,03% | الأسهم |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1118336 | 32999 | 0,03% | الأسهم |
| STIFEL FINANCIAL CORP | $1079432 | 31851 | 0,03% | الأسهم |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $1062621 | 31355 | 0,03% | الأسهم |
| Quadrature Capital Ltd | $1036797 | 30593 | 0,03% | الأسهم |
| VOYA INVESTMENT MANAGEMENT LLC | $916725 | 27050 | 0,02% | الأسهم |
| Eleva Capital SAS | $823329 | 25721 | 0,02% | الأسهم |
| AQR CAPITAL MANAGEMENT LLC | $768998 | 22691 | 0,02% | الأسهم |
| HighVista Strategies LLC | $708470 | 20905 | 0,02% | الأسهم |
| GLENMEDE TRUST CO NA | $692033 | 20420 | 0,02% | الأسهم |
| DNB Asset Management AS | $680850 | 20090 | 0,02% | الأسهم |
| Engineers Gate Manager LP | $661838 | 19529 | 0,02% | الأسهم |
| State of New Jersey Common Pension Fund D | $661465 | 19518 | 0,02% | الأسهم |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $647265 | 19099 | 0,02% | الأسهم |
| Caption Management, LLC | $633743 | 18700 | 0,02% | عقد خيار الشراء |
| Point72 Asset Management, L.P. | $620187 | 18300 | 0,02% | عقد خيار الشراء |
| Point72 Asset Management, L.P. | $620187 | 18300 | 0,02% | عقد خيار البيع |
| WELLS FARGO & COMPANY/MN | $611308 | 18038 | 0,02% | الأسهم |
| GOLDMAN SACHS GROUP INC | $576130 | 17000 | 0,01% | عقد خيار الشراء |
| ARIZONA STATE RETIREMENT SYSTEM | $564472 | 16656 | 0,01% | الأسهم |
| Vanguard Investments Australia, Ltd. | $534581 | 15774 | 0,01% | الأسهم |
| ENVESTNET ASSET MANAGEMENT INC | $525973 | 15520 | 0,01% | الأسهم |
| SBI Okasan Asset Management Co.Ltd. | $504663 | 14900 | 0,01% | الأسهم |
| AlphaCentric Advisors LLC | $503877 | 14868 | 0,01% | الأسهم |
| ROYAL BANK OF CANADA | $487000 | 14362 | 0,01% | الأسهم |
| KLP KAPITALFORVALTNING AS | $464293 | 13700 | 0,01% | الأسهم |
| KEYBANK NATIONAL ASSOCIATION/OH | $422947 | 12480 | 0,01% | الأسهم |
| TWO SIGMA INVESTMENTS, LP | $406714 | 12001 | 0,01% | الأسهم |
| PSP Research LLC | $406680 | 12000 | 0,01% | الأسهم |
| JANE STREET GROUP, LLC | $406680 | 12000 | 0,01% | عقد خيار الشراء |
| PTM WEALTH MANAGEMENT, LLC | $382356 | 12900 | 0,01% | الأسهم |
| Virtus Investment Advisers, LLC | $364758 | 10763 | 0,01% | الأسهم |
| Financiere des Professionnels - Fonds d'investissement inc. | $364114 | 10744 | 0,01% | الأسهم |
| Cerity Partners LLC | $340967 | 10061 | 0,01% | الأسهم |
| Caitong International Asset Management Co., Ltd | $328123 | 9682 | 0,01% | الأسهم |
| Brevan Howard Capital Management LP | $323582 | 9548 | 0,01% | الأسهم |
| LETKO, BROSSEAU & ASSOCIATES INC | $321108 | 9475 | 0,01% | الأسهم |
| BAMCO INC /NY/ | $305010 | 9000 | 0,01% | الأسهم |
| AdvisorNet Financial, Inc | $283829 | 8375 | 0,01% | الأسهم |
| Pictet Asset Management Holding SA | $277051 | 8175 | 0,01% | الأسهم |
| Creative Planning | $275695 | 8135 | 0,01% | الأسهم |
| BARCLAYS PLC | $273560 | 8072 | 0,01% | الأسهم |
| CITIGROUP INC | $272001 | 8026 | 0,01% | الأسهم |
| Mesirow Financial Investment Management, Inc. | $252989 | 7465 | 0,01% | الأسهم |
| JANE STREET GROUP, LLC | $247397 | 7300 | 0,01% | عقد خيار البيع |
| PNC Financial Services Group, Inc. | $247091 | 7291 | 0,01% | الأسهم |
| US BANCORP \DE\ | $246922 | 7286 | 0,01% | الأسهم |
| Persistent Asset Partners Ltd | $246855 | 7284 | 0,01% | الأسهم |
| Wealth Management Associates, Inc. | $239094 | 7055 | 0,01% | الأسهم |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $237501 | 7008 | 0,01% | الأسهم |
| Centiva Capital, LP | $237230 | 7000 | 0,01% | الأسهم |
| Invesco Ltd. | $224250 | 6617 | 0,01% | الأسهم |
| Allianz Asset Management GmbH | $223674 | 6600 | 0,01% | الأسهم |
| CIBC Private Wealth Group LLC | $217282 | 7640 | 0,01% | الأسهم |
| GUGGENHEIM CAPITAL LLC | $216896 | 6400 | 0,01% | الأسهم |
| MARSHALL FINANCIAL GROUP INC /ADV | $213300 | 7500 | 0,01% | الأسهم |
| Mirae Asset Global Investments Co., Ltd. | $177177 | 5228 | 0,00% | الأسهم |
| Quarry LP | $153996 | 4544 | 0,00% | الأسهم |
| Tower Research Capital LLC (TRC) | $152505 | 4500 | 0,00% | الأسهم |
| Mitsubishi UFJ Trust & Banking Corp | $146744 | 4330 | 0,00% | الأسهم |
| WELLS FARGO & COMPANY/MN | $128782 | 3800 | 0,00% | عقد خيار البيع |
| Duquesne Family Office LLC | $104047 | 3070146 | 0,00% | الأسهم |
| Quantbot Technologies LP | $91300 | 2694 | 0,00% | الأسهم |
| Toroso Investments, LLC | $84192 | 2400 | 0,00% | عقد خيار الشراء |
| GF FUND MANAGEMENT CO. LTD. | $82488 | 2434 | 0,00% | الأسهم |
| NATIONAL BANK OF CANADA /FI/ | $61431 | 1813 | 0,00% | الأسهم |
| Federation des caisses Desjardins du Quebec | $60494 | 1785 | 0,00% | الأسهم |
| Parallel Advisors, LLC | $47446 | 1400 | 0,00% | الأسهم |
| Bayforest Capital Ltd | $43278 | 1277 | 0,00% | الأسهم |
| PRICE T ROWE ASSOCIATES INC /MD/ | $39562 | 1167357 | 0,00% | الأسهم |
| THURSTON, SPRINGER, MILLER, HERD & TITAK, INC. | $36160 | 1067 | 0,00% | الأسهم |
| Farther Finance Advisors, LLC | $34093 | 1006 | 0,00% | الأسهم |
| CWM, LLC | $32586 | 1018 | 0,00% | الأسهم |
| Cheviot Value Management, LLC | $26976 | 796 | 0,00% | الأسهم |
| NWI MANAGEMENT LP | $23791 | 702000 | 0,00% | الأسهم |
| SBI Securities Co., Ltd. | $20842 | 615 | 0,00% | الأسهم |
| Handelsbanken Fonder AB | $13409 | 418900 | 0,00% | الأسهم |
| HRT FINANCIAL LP | $11856 | 349843 | 0,00% | الأسهم |
| Stone House Investment Management, LLC | $11014 | 325 | 0,00% | الأسهم |
| LORD, ABBETT & CO. LLC | $10389 | 306560 | 0,00% | الأسهم |
| Global Retirement Partners, LLC | $9150 | 270 | 0,00% | الأسهم |
| FIL Ltd | $7354 | 217 | 0,00% | الأسهم |
| NISA INVESTMENT ADVISORS, LLC | $7083 | 209 | 0,00% | الأسهم |
| Arax Advisory Partners | $6032 | 178 | 0,00% | الأسهم |
| JONES FINANCIAL COMPANIES LLLP | $5584 | 168 | 0,00% | الأسهم |
| Continuum Advisory, LLC | $5219 | 154 | 0,00% | الأسهم |
| OSAIC HOLDINGS, INC. | $4710 | 139 | 0,00% | الأسهم |
| Clearstead Advisors, LLC | $2576 | 76 | 0,00% | الأسهم |
| ORG Partners LLC | $2104 | 60 | 0,00% | الأسهم |
| Essential Partners LLC | $1796 | 53 | 0,00% | الأسهم |
| Lindbrook Capital, LLC | $921 | 45 | 0,00% | الأسهم |
| Allworth Financial LP | $848 | 25 | 0,00% | الأسهم |
| True Wealth Design, LLC | $712 | 21 | 0,00% | الأسهم |
| FIDUCIARY FINANCIAL ADVISORS | $441 | 13 | 0,00% | الأسهم |
| EverSource Wealth Advisors, LLC | $373 | 11 | 0,00% | الأسهم |
| GAMMA Investing LLC | $305 | 9 | 0,00% | الأسهم |
| Sunbelt Securities, Inc. | $256 | 8 | 0,00% | الأسهم |
| SG Americas Securities, LLC | $115 | 3384 | 0,00% | الأسهم |
| ROTHSCHILD INVESTMENT LLC | $102 | 3 | 0,00% | الأسهم |
| IFP Advisors, Inc | $102 | 3 | 0,00% | الأسهم |
| KBC Group NV | $84 | 2483 | 0,00% | الأسهم |
| DUPONT CAPITAL MANAGEMENT CORP | $34 | 1 | 0,00% | الأسهم |