LXRX Lexicon Pharmaceuticals, Inc. - Common Stock

NASDAQ · Pharmaceuticals · Auf SEC EDGAR ansehen ↗
$2,45
Kurs · Aug 19, 2026
Fundamentaldaten per Aug 6, 2026

Über Lexicon Pharmaceuticals, Inc. - Common Stock Unternehmensübersicht von Wikipedia

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 100 potential therapeutic targets. Lexicon has advanced multiple drug candidates into human clinical trials and has a broad and diverse pipeline of drug targets behind its clinical programs. Lexicon is pursuing drug targets in five therapeutic areas including oncology, gastroenterology, immunology, metabolism, and ophthalmology.

Mehr lesen

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 100 potential therapeutic targets. Lexicon has advanced multiple drug candidates into human clinical trials and has a broad and diverse pipeline of drug targets behind its clinical programs. Lexicon is pursuing drug targets in five therapeutic areas including oncology, gastroenterology, immunology, metabolism, and ophthalmology.

The company's clinical drug candidates include sotagliflozin (LX4211) for the treatment of type 2 diabetes; LX1033 for the treatment of irritable bowel syndrome and other gastrointestinal disorders; telotristat ethyl (LX1032) for the treatment of the symptoms associated with carcinoid syndrome; and LX2931 for the treatment of autoimmune diseases, such as rheumatoid arthritis.

Company history

Lexicon Pharmaceuticals was founded in September 1995 as a biotech venture of Baylor College of Medicine. The company went public in April 2000 with $220 million initial public offerings. In June, 2001 Lexicon purchased a privately owned small chemical library synthesis company, Coelacanth Corporation in Princeton, New Jersey, which became the site for the company's small molecule and medicinal chemistry efforts. The company's original name was Lexicon Genetics Incorporated, but in 2007, the name changed to Lexicon Pharmaceuticals, Inc. to reflect a renewed focus on drug development.

The company initially focused on using gene knockout technology to define the function of genes. This effort complemented and benefited from the international effort to sequence the human and mouse genomes (see Human Genome Project). Using its proprietary gene trapping and gene targeting technologies, the company created A repository of genetically modified mouse embryonic stem cells, known as OmniBank, and established a large-scale mammalian knockout program to discover the physiological and behavioral functions of the most druggable mammalian genes. The information collected from this program is stored in the company's LexVision database, which contains almost 5,000 gene knockouts studied. Over the years, Lexicon evolved from a genomics company into a drug discovery and development company focused on discovering and developing treatments for human disease. The company currently has multiple drug candidates in various stages of clinical trials.

In 2016, the company was ranked #8 on the Deloitte Fast 500 North America list.

Technology

Lexicon uses patented gene trapping and gene targeting technologies to generate and study knockout mice to discover the physiological and behavioral effects that result from the disruption of a single gene knockout. Because there is a close similarity in gene function and physiology between mice and humans, with a large majority of human genes having a counterpart in the mouse genome, knockout mouse technology has become a powerful tool in the discovery of new medicines.

The value of Lexicon's technology in drug discovery has been described in a retrospective analysis by the scientific journal Nature. The conclusion of this analysis was that, in most cases, there was a direct correlation when comparing the physiological characteristics, or phenotypes, of knockout mice to the therapeutic effect of the 100 best-selling drugs of 2001. The tremendous utility of knockout mouse technology was recognized in 2007 with the Nobel Prize in Physiology or Medicine to Drs. Mario Capecchi, Martin Evans, and Oliver Smithies.

In developing small molecule drugs for its validated targets, Lexicon uses medicinal chemistry known as "click chemistry." Dr. K. Barry Sharpless, who was awarded the 2001 Nobel Prize in Chemistry, developed this tools for the rapid synthesis of novel compounds. Lexicon uses solution-phase chemistry to generate diverse libraries of optically pure compounds that are built using organic reactions that allow the company to generate collections of diffrent compounds and to tailor the compound collections to address various therapeutic target families. Lexicon's medicinal chemists design these libraries by analyzing the chemical structures of drugs that have been proven safe and effective against human disease and using that knowledge in the design of scaffolds and chemical building blocks for the generation of large numbers of new drug-like compounds.

Locations

Lexicon operates from two locations found in Texas and New Jersey. The corporate headquarters are in The Woodlands, Texas just north of Houston. This location serves as Lexicon's primary research facility to discover and validate the company's drug targets and test drug candidates in preclinical research. The company's clinical development and regulatory team is also based at the corporate headquarters.

Lexicon's campus in Princeton, New Jersey is the home of Lexicon's small molecule medicinal chemistry and preclinical development efforts. This site serves as Lexicon's primary medicinal chemistry site to create new chemical entities for therapeutic development.

== References ==

Quelle: Wikipedia (Englisch), CC BY-SA 4.0 · Auf Wikipedia ansehen ↗

Wikidata ↗

LXRX Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne

Kurs
$2.44
Marktkapitalisierung
$894M
P/E (TTM)
-17.5
EPS (TTM)
$-0.14
Umsatz (TTM)
$50M
Dividendenrendite
ROE
-39.7%
Verschuldungsgrad
0.5
52W-Spanne
$1 – $3

LXRX Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen

10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends

Umsatz & Nettoergebnis $50M
10-point trend, -37.2%
2016-12-31 2025-12-31
EPS $-0.14
9-point trend, +88.0%
2017-12-31 2025-12-31
Freier Cashflow $-68M
10-point trend, +61.4%
2016-12-31 2025-12-31
Margen -101.1%

Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?

Kennzahl
5-Jahres-Trend
LXRX
Peer-Median
P/E (TTM)
5-point trend, -25.1%
-17.5
29.9
P/S (TTM) (K/V (TTM))
5-point trend, +514.6%
18.0
14.4
P/B (K/B)
5-point trend, +3.5%
8.3
4.4
EV / EBITDA
5-point trend, +1.2%
-17.6
Price / FCF (Kurs / FCF)
5-point trend, -259.3%
-13.2

Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC

Kennzahl
5-Jahres-Trend
LXRX
Peer-Median
Operating Margin (Betriebsgewinnmarge)
5-point trend, +99.7%
-98.2%
Net Profit Margin (Nettogewinnmarge)
5-point trend, +99.7%
-101.1%
0.70%
ROA
5-point trend, +59.6%
-20.8%
-0.55%
ROE
5-point trend, +38.9%
-39.7%
-2.5%

Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke

Kennzahl
5-Jahres-Trend
LXRX
Peer-Median
Debt / Equity (Fremdkapital / Eigenkapital)
5-point trend, +574.1%
0.5
Current Ratio (Liquiditätsgrad)
5-point trend, +21.5%
4.9
3.9
Quick Ratio
5-point trend, +20.5%
4.7

Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR

Kennzahl
5-Jahres-Trend
LXRX
Peer-Median
Revenue YoY (Umsatz YoY)
5-point trend, +16612.4%
60.2%
Revenue CAGR 3Y (Umsatz CAGR 3J)
5-point trend, +16612.4%
610.2%
Revenue CAGR 5Y (Umsatz CAGR 5J)
5-point trend, +16612.4%
15.7%

Kennzahlen pro Aktie EPS, Buchwert pro Aktie, Cashflow pro Aktie, Dividende pro Aktie

Kennzahl
5-Jahres-Trend
LXRX
Peer-Median
EPS (Diluted) (EPS (Verwässert))
5-point trend, +76.7%
$-0.14

Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag

Kennzahl
5-Jahres-Trend
LXRX
Peer-Median

LXRX Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial

KAUF 11 Analysten
  • Starker Kauf 3 27,3%
  • Kauf 5 45,5%
  • Halten 3 27,3%
  • Verkauf 0 0,0%
  • Starker Verkauf 0 0,0%

12-Monats-Kursziel

5 Analysten · 2026-08-19
Median-Ziel $3.10 +26,8%
Mittelwert-Ziel $3.86 +57,7%

Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum

Durchschn. Überraschung
0.03%
Zeitraum EPS Actual EPS est. Überraschung
30. Juni 2026 $-0.07 $-0.05 -0.02%
31. März 2026 $0.00 $-0.04 0.04%
31. Dezember 2025 $-0.04 $-0.07 0.03%
30. September 2025 $-0.04 $-0.07 0.03%
30. Juni 2025 $0.01 $-0.08 0.09%
31. März 2025 $-0.07 $-0.10 0.03%

Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen

Ticker Marktkapitalisierung P/E Umsatz Vj. Nettomarge ROE Bruttogewinnmarge
LXRX $421M -8.2 60.2% -101.1% -39.7%
ANRO $568M -8.1 -46.1%
EYPT $1.51B -5.8 -27.5% -739.4% -84.0%
OMER $1.23B -343.6 1.9%
PCRX $1.06B 161.8 3.6% 0.97% 0.97%
COLL $1.47B 26.8 23.6% 8.1% 23.5% 59.4%
AMPH $1.22B 13.2 -1.7% 13.6% 12.7% 49.5%
ACRS $363M -5.7 -58.2% -829.6% -55.3%
SGP 50.0%
LLY 46.8 44.7% 31.7% 101.2%

Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow

Gewinn- und Verlustrechnung 16
Jährliche Gewinn- und Verlustrechnung-Daten für LXRX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +117.9% $50M $31M $1M $139.0K $298.0K $24M $322M $63M $92M $79M $130M $23M
Cost of Revenue 11-point trend, +274000.00 $274.0K $616.0K $85.0K $0 $0 $2M $3M $2M $2M $0 $0 ·
R&D Expense 12-point trend, -31.5% $61M $84M $59M $53M $55M $154M $92M $100M $152M $164M $95M $89M
SG&A Expense 12-point trend, +92.3% $37M $143M $114M $48M $32M $47M $57M $64M $66M $43M $24M $19M
Operating Expenses 12-point trend, -19.9% $99M $228M $173M $101M $87M $204M $181M $166M $222M $206M $129M $123M
Operating Income 12-point trend, +51.3% $-49M $-197M $-172M $-101M $-87M $-48M $141M $-103M $-131M $-127M $1M $-100M
Interest Expense 9-point trend, +23.4% · · · $3M $802.0K $15M $21M $21M $7M $7M $7M $2M
Other Non-op 12-point trend, +206.4% $7M $12M $8M $2M $134.0K $3M $3M $4M $2M $2M $572.0K $2M
Pretax Income 8-point trend, +12.6% · · · · $-88M $-59M $124M $-121M $-136M $-131M $-5M $-100M
Income Tax 7-point trend, +100.0% · $0 $0 $0 $0 · · · · $0 $0 $-70.0K
Net Income 12-point trend, +49.8% $-50M $-200M $-177M $-102M $-88M $-59M $130M $-121M $-123M $-131M $-5M $-100M
EPS (Basic) 9-point trend, +88.0% $-0.14 $-0.63 $-0.80 $-0.62 $-0.60 $-0.53 $1.23 $-1.14 $-1.17 · · ·
EPS (Diluted) 9-point trend, +88.0% $-0.14 $-0.63 $-0.80 $-0.62 $-0.60 $-0.53 $1.16 $-1.14 $-1.17 · · ·
Shares (Basic) 5-point trend, +149.3% 363,053,000 320,031,000 221,130,000 165,733,000 145,652,000 · · · · · · ·
Shares (Diluted) 9-point trend, +245.0% 363,053,000 320,031,000 221,130,000 165,733,000 145,652,000 110,841,000 116,747,000 105,830,000 105,237,000 · · ·
EBITDA 11-point trend, +50.9% $-48M $-197M $-171M $-100M $-87M $-45M $145M $-100M $-133M $-135M · $-98M
Bilanz 30
Jährliche Bilanz-Daten für LXRX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, -75.0% $34M $67M $22M $46M $64M $126M $36M $80M $62M $47M $203M $137M
Short-term Investments 12-point trend, -69.4% $62M $171M $148M $92M $23M $26M $236M $80M $249M $300M $318M $202M
Receivables 12-point trend, +130.3% $2M $3M $1M $28.0K $14.0K $395.0K $57M $6M $5M $7M $911.0K $1M
Inventory 9-point trend, +281000.00 $281.0K $231.0K $381.0K $0 · $0 $4M $5M $2M $0 · ·
Other Current Assets 12-point trend, -37.0% $3M $5M $5M $2M $2M $5M $5M $3M $4M $4M $10M $5M
Current Assets 12-point trend, -72.4% $102M $246M $177M $141M $89M $158M $338M $173M $322M $358M $532M $369M
PP&E (Net) 12-point trend, +72.5% $2M $2M $2M $2M $1M $295.0K $14M $16M $18M $19M $21M $1M
PP&E (Gross) 12-point trend, -87.8% $5M $5M $7M $6M $6M $6M $76M $76M $76M $79M $81M $37M
Accum. Depreciation 12-point trend, -92.5% $3M $2M $5M $4M $5M $6M $62M $60M $59M $60M $59M $36M
Goodwill Flat — no change across 12 periods $45M $45M $45M $45M $45M $45M $45M $45M $45M $45M $45M $45M
Intangibles 6-point trend, -63.0% · · · · · · $20M $50M $52M $53M $53M $53M
Other Non-current Assets 12-point trend, -89.2% $368.0K $368.0K $828.0K $412.0K $2M $1M $2M $285.0K $429.0K $461.0K $433.0K $3M
Total Assets 12-point trend, -60.8% $185M $298M $229M $194M $137M $204M $418M $284M $437M $476M $652M $471M
Accounts Payable 12-point trend, -76.4% $3M $15M $14M $10M $9M $5M $12M $12M $39M $53M $20M $13M
Accrued Liabilities 12-point trend, +30.3% $13M $30M $17M $13M $13M $30M $42M $21M $12M $32M $25M $10M
Current Liabilities 12-point trend, -53.6% $21M $45M $32M $23M $22M $47M $65M $37M $105M $165M $123M $45M
Capital Leases 4-point trend, +21.7% $7M $5M $5M $5M · · · · · · · ·
Deferred Tax 6-point trend, -100.0% · · · · · · $0 $6M $6M $19M $19M $19M
Other Non-current Liabilities 12-point trend, -69.5% $7M $7M $5M $5M $1M $611.0K $1M $238.0K $292.0K $805.0K $14M $24M
Total Liabilities 12-point trend, -58.7% $77M $152M $136M $77M $23M $47M $301M $311M $368M $318M $366M $187M
Long-term Debt 11-point trend, -49.8% $54M $100M · $49M $0 $12M $249M $250M $252M $101M $106M $108M
Total Debt 10-point trend, -49.8% $54M $100M $100M · $0 $12M $245M $245M $246M $101M · $108M
Common Stock 12-point trend, +251.9% $366.0K $363.0K $245.0K $189.0K $150.0K $142.0K $106.0K $106.0K $106.0K $105.0K $104.0K $104.0K
Paid-in Capital 12-point trend, +53.2% $2.13B $2.12B $1.86B $1.71B $1.61B $1.56B $1.46B $1.45B $1.44B $1.41B $1.40B $1.39B
Retained Earnings 12-point trend, -82.7% $-2.02B $-1.97B $-1.77B $-1.59B $-1.49B $-1.40B $-1.34B $-1.47B $-1.37B $-1.25B $-1.11B $-1.10B
Treasury Stock 12-point trend, +117.0% $5M $5M $3M $2M $8M $5M $4M $3M $2M $3M $3M $2M
AOCI 12-point trend, +147.6% $30.0K $119.0K $31.0K $-428.0K $-10.0K $-6.0K $84.0K $-12.0K $-222.0K $-195.0K $-219.0K $-63.0K
Stockholders' Equity 12-point trend, -62.1% $108M $146M $93M $117M $114M $156M $117M $-26M $68M $168M $286M $284M
Liabilities + Equity 12-point trend, -60.8% $185M $298M $229M $194M $137M $204M $418M $284M $437M $476M $652M $471M
Shares Outstanding 11-point trend, +252.9% 365,848,216 363,020,303 · 189,214,000 150,082,000 142,289,000 106,679,000 106,162,000 105,711,000 104,582,000 103,860,000 103,663,000
Cashflow 17
Jährliche Cashflow-Daten für LXRX
Kennzahl Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, -67.8% $621.0K $534.0K $554.0K $427.0K $292.0K $3M $4M $4M $3M $2M $727.0K $2M
Stock-based Comp 12-point trend, +76.8% $13M $13M $14M $12M $11M $13M $14M $12M $9M $7M $7M $7M
Deferred Tax 9-point trend, +100.0% · · · $0 $0 $0 $-6M $0 $-13M $0 $0 $-70.0K
Amort. of Intangibles 2-point trend, +20.0% · · · · · · · $2M $2M · · ·
Other Non-cash 11-point trend, -296.5% $-31M $8M $328.0K $1M $-10M $-101M $-28M $-43M $-57M $-44M · $16M
Operating Cash Flow 12-point trend, +10.3% $-68M $-179M $-162M $-89M $-87M $-143M $114M $-149M $-185M $-176M $185M $-76M
CapEx 12-point trend, -100.0% $0 $1M $470.0K $1M $1M $87.0K $70.0K $95.0K $228.0K $231.0K $910.0K $80.0K
Investing Cash Flow 12-point trend, +204.2% $113M $-15M $-50M $-71M $2M $381M $-156M $170M $51M $18M $-117M $-108M
Debt Issued 11-point trend, -100.0% $0 $0 $50M $49M · $0 $0 $13M $146M $0 $0 $84M
Net Debt Issued 10-point trend, -100.0% $0 $0 · $49M $-12M $-217M $-1M $-2M $144M $-2M · $82M
Stock Issued 12-point trend, -100.0% $0 $0 $139M $94M $37M $70M $0 $732.0K $8M $4M $114.0K $202M
Stock Repurchased 11-point trend, +95.0% · $2M $824.0K $864.0K $3M $1M $941.0K $972.0K $2M $621.0K $357.0K $887.0K
Net Stock Activity 11-point trend, -100.0% $0 $-2M $138M $93M $34M $69M $-941.0K $-240.0K $6M $3M · $201M
Financing Cash Flow 12-point trend, -117.1% $-48M $238M $188M $142M $23M $-148M $-2M $-2M $150M $987.0K $-2M $284M
Net Change in Cash 12-point trend, -103.3% $-3M $44M $-24M $-18M $-62M $90M $-44M $19M $15M $-156M $66M $100M
Free Cash Flow 11-point trend, +10.4% $-68M $-180M $-162M $-90M $-88M $-143M $114M $-149M $-186M $-176M · $-76M
Levered FCF 2-point trend, -134.0% · · · · · · · · · $-182M · $-78M
Rentabilität 7
Jährliche Rentabilität-Daten für LXRX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, +77.6% -98.2% -634.2% -14264.9% -72489.2% -29224.8% -199.2% 43.9% -163.4% -151.3% -164.6% · -439.2%
Net Margin 11-point trend, +77.0% -101.1% -644.8% -14710.9% -73341.0% -29449.0% -244.1% 40.4% -190.7% -142.9% -169.7% · -438.8%
Pretax Margin 7-point trend, -6605.9% · · · · -29449.0% -244.1% 38.5% -190.7% -156.9% -169.7% · -439.1%
EBITDA Margin 11-point trend, +77.5% -97.0% -632.5% -14218.9% -72182.0% -29126.9% -187.0% 45.1% -157.6% -147.5% -162.1% · -430.7%
ROA 11-point trend, +22.6% -20.8% -75.9% -83.6% -61.6% -51.5% -18.9% 37.1% -33.5% -28.3% -25.1% · -26.9%
ROE 11-point trend, +10.1% -39.7% -167.7% -168.5% -88.4% -65.0% -42.8% 287.0% -576.0% -117.5% -63.8% · -44.2%
ROIC 2-point trend, -106.9% · · · · · · · · · -53.0% · -25.6%
Liquidität & Solvenz 5
Jährliche Liquidität & Solvenz-Daten für LXRX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -40.5% 4.9 5.4 5.6 6.1 4.0 3.4 5.2 4.7 2.6 2.2 · 8.2
Quick Ratio 11-point trend, -37.6% 4.7 5.3 5.4 6.0 3.9 3.3 5.0 4.5 2.5 2.2 · 7.6
Debt / Equity 10-point trend, +32.5% 0.5 0.7 1.1 · 0.0 0.1 2.1 -9.3 4.7 0.6 · 0.4
LT Debt / Equity 9-point trend, +49.1% 0.5 0.7 1.1 · · 0.0 2.0 -9.2 4.4 0.5 · 0.3
Interest Coverage 8-point trend, +18.6% · · · -36.2 -108.6 -3.3 6.8 -5.0 -19.6 -20.9 · -44.5
Effizienz 3
Jährliche Effizienz-Daten für LXRX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, +236.1% 0.2 0.1 0.0 0.0 0.0 0.1 0.9 0.2 0.2 0.1 · 0.1
Inventory Turnover 7-point trend, -45.1% 1.1 2.0 0.4 · · 0.9 0.7 0.8 1.9 · · ·
Receivables Turnover 11-point trend, -32.1% 17.0 13.9 2.3 6.6 1.5 0.8 10.3 11.8 14.7 19.8 · 25.0
Pro Aktie 5
Jährliche Pro Aktie-Daten für LXRX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Book Value / Share 9-point trend, -24.9% $0.29 · · $0.62 $0.76 $1.10 $1.10 $-0.25 $0.49 $1.50 · $0.39
Revenue / Share 6-point trend, -95.0% $0.14 $0.10 $0.01 · $0.00 $0.22 $2.76 · · · · ·
Cash Flow / Share 6-point trend, -119.2% $-0.19 $-0.56 $-0.73 · $-0.60 $-1.29 $0.97 · · · · ·
Cash / Share 9-point trend, -50.4% $0.09 · · $0.24 $0.43 $0.89 $0.34 $0.76 $0.58 $0.45 · $0.19
EPS (TTM) 11-point trend, -16.7% $-0.14 $-0.63 $-0.80 $-0.62 $-0.60 $-0.53 $1.16 $-1.14 $-1.17 $-0.12 $-0.12 ·
Wachstumsraten 3
Jährliche Wachstumsraten-Daten für LXRX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +161.0% 60.2% 2481.5% 766.2% -53.4% -98.8% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +1066.8% 610.2% 370.7% -63.1% · · · · · · · · ·
Revenue CAGR 5Y 15.7% · · · · · · · · · · ·
Bewertung (TTM) 14
Jährliche Bewertung (TTM)-Daten für LXRX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +117.9% $50M $31M $1M $139.0K $298.0K $24M $322M $63M $92M $79M $130M $23M
Net Income TTM 12-point trend, +49.8% $-50M $-200M $-177M $-102M $-88M $-59M $130M $-121M $-123M $-131M $-5M $-100M
Market Cap 9-point trend, -90.9% $421M · · $361M $591M $487M $443M $705M $1.04B $1.45B · $4.62B
Enterprise Value 8-point trend, -91.4% $378M · · · $505M $346M $416M $790M $979M $1.20B · $4.39B
P/E 11-point trend, +92.6% -8.2 -1.2 -1.9 -3.1 -6.6 -6.5 3.6 -5.8 -8.4 -115.2 -110.9 ·
P/S 9-point trend, -95.8% 8.4 · · 2600.0 1984.3 20.3 1.4 11.2 11.4 18.2 · 202.3
P/B 9-point trend, -76.0% 3.9 · · 3.1 5.2 3.1 3.8 -26.7 20.0 9.2 · 16.3
P / Tangible Book 4-point trend, +53.5% 6.7 · · 5.0 8.6 4.4 · · · · · ·
P / Cash Flow 9-point trend, +89.9% -6.2 · · -4.1 -6.8 -3.4 3.9 -4.7 -5.6 -8.2 · -61.1
P / FCF 9-point trend, +89.8% -6.2 · · -4.0 -6.7 -3.4 3.9 -4.7 -5.6 -8.2 · -61.1
EV / EBITDA 8-point trend, +82.4% -7.8 · · · -5.8 -7.7 2.9 -7.9 -7.3 -8.9 · -44.6
EV / FCF 8-point trend, +90.4% -5.6 · · · -5.7 -2.4 3.7 -5.3 -5.3 -6.8 · -58.0
EV / Revenue 8-point trend, -96.0% 7.6 · · · 1693.2 14.4 1.3 12.5 10.7 15.2 · 192.1
Earnings Yield 11-point trend, -1252.2% -12.2% -85.1% -52.3% -32.5% -15.2% -15.5% 28.0% -17.2% -11.8% -0.87% -0.90% ·

Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre

Gewinn- und Verlustrechnung
2025-12-312024-12-312023-12-312022-12-312021-12-31
Umsatz $50M$31M$1M$139.0K$298.0K
Betriebsgewinnmarge % -98.2%-634.2%-14264.9%-72489.2%-29224.8%
Nettoergebnis $-50M$-200M$-177M$-102M$-88M
Verwässerte EPS $-0.14$-0.63$-0.80$-0.62$-0.60
Bilanz
2025-12-312024-12-312023-12-312022-12-312021-12-31
Fremdkapital / Eigenkapital 0.50.71.10.0
Liquiditätsgrad 4.95.45.66.14.0
Quick Ratio 4.75.35.46.03.9
Cashflow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Freier Cashflow $-68M$-180M$-162M$-90M$-88M

Neueste Nachrichten Aktuelle Schlagzeilen über dieses Unternehmen

Meine Kennzahlen Ihre persönliche Watchlist — ausgewählte Zeilen aus den vollständigen Fundamentaldaten

📊

Wählen Sie die Kennzahlen, die für Sie wichtig sind — klicken Sie auf das ➕ neben jeder Zeile in den vollständigen Fundamentaldaten oben.

Ihre Auswahl wird gespeichert und begleitet Sie über alle Ticker hinweg.

Institutionelle Eigentümer (13F) 169 Einreicher · $760.9M gesamt · Stand 30. Juni 2026

Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.

Institutionelle Aktivität — Q2 2026 vs. Vorquartal
Neue Positionen Geschlossene Positionen Erhöht Abgenommen Nettoveränderung der Aktien
48 (+19 vs. Vorquartal) 26 (+13 vs. Vorquartal) 34 (-11 vs. Vorquartal) 37 (+17 vs. Vorquartal) +36.5M

Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.

Institution Wert Aktien % der verfolgten 13F Typ
Artal Group S.A. $420.374.549 175.156.062 55,25% Aktien
Siren, L.L.C. $106.328.443 44.303.518 13,97% Aktien
FMR LLC $65.057.059 27.107.108 8,55% Aktien
Sessa Capital IM, L.P. $45.506.006 18.960.836 5,98% Aktien
VANGUARD CAPITAL MANAGEMENT LLC $23.762.899 9.901.208 3,12% Aktien
Point72 Asset Management, L.P. $19.803.180 8.251.325 2,60% Aktien
GEODE CAPITAL MANAGEMENT, LLC $12.946.507 5.393.025 1,70% Aktien
STATE STREET CORP $11.802.646 4.917.769 1,55% Aktien
VANGUARD PORTFOLIO MANAGEMENT LLC $5.658.598 2.357.749 0,74% Aktien
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4.696.260 1.956.775 0,62% Aktien
VANGUARD FIDUCIARY TRUST CO $3.922.970 1.634.571 0,52% Aktien
CIBC Private Wealth Group LLC $3.240.347 2.400.257 0,43% Aktien
Ishara Investments LP $3.050.400 1.271.000 0,40% Aktien
MILLENNIUM MANAGEMENT LLC $2.722.150 1.134.229 0,36% Aktien
RENAISSANCE TECHNOLOGIES LLC $2.704.800 1.127.000 0,36% Aktien
MACKENZIE FINANCIAL CORP $2.312.050 963.354 0,30% Aktien
ADAR1 Capital Management, LLC $1.800.000 750.000 0,24% Aktien
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1.604.400 668.500 0,21% Kaufoption
TWO SIGMA INVESTMENTS, LP $1.544.266 643.444 0,20% Aktien
JANE STREET GROUP, LLC $1.398.960 582.900 0,18% Kaufoption
CITADEL ADVISORS LLC $1.348.733 561.972 0,18% Aktien
VANGUARD GROUP INC $1.277.587 1.110.945 0,17% Aktien
Compagnie Lombard Odier SCmA $1.152.000 480.000 0,15% Aktien
BARCLAYS PLC $890.636 371.098 0,12% Aktien
CITADEL ADVISORS LLC $886.320 369.300 0,12% Kaufoption
XTX Topco Ltd $858.905 357.877 0,11% Aktien
GOLDMAN SACHS GROUP INC $725.810 302.421 0,10% Aktien
CANADA PENSION PLAN INVESTMENT BOARD $618.960 257.900 0,08% Aktien
RHUMBLINE ADVISERS $616.523 256.885 0,08% Aktien
WELLS FARGO & COMPANY/MN $544.865 227.027 0,07% Aktien
GROUP ONE TRADING LLC $420.031 175.013 0,06% Aktien
Virtus Investment Advisers, LLC $408.996 170.415 0,05% Aktien
Headlands Technologies LLC $401.275 167.198 0,05% Aktien
Ikarian Capital, LLC $395.218 164.674 0,05% Aktien
CITIGROUP INC $386.021 160.842 0,05% Aktien
Quarry LP $374.846 156.186 0,05% Aktien
MetLife Investment Management, LLC $351.384 146.410 0,05% Aktien
Bank of New York Mellon Corp $345.307 143.878 0,05% Aktien
BANK OF AMERICA CORP /DE/ $344.321 143.467 0,05% Aktien
PANAGORA ASSET MANAGEMENT INC $316.901 132.042 0,04% Aktien
State of Wyoming $285.816 119.090 0,04% Aktien
BlackRock, Inc. $284.436 118.515 0,04% Aktien
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $273.874 114.114 0,04% Aktien
Cornerstone Investment Partners, LLC $272.974 113.739 0,04% Aktien
Invesco Ltd. $238.190 99.246 0,03% Aktien
ALGERT GLOBAL LLC $221.160 92.150 0,03% Aktien
TWO SIGMA ADVISERS, LP $208.124 180.977 0,03% Aktien
BANK OF NOVA SCOTIA $207.857 86.607 0,03% Aktien
LPL Financial LLC $203.799 84.916 0,03% Aktien
Vanguard Global Advisers, LLC $187.070 77.946 0,02% Aktien
AQR CAPITAL MANAGEMENT LLC $180.101 75.042 0,02% Aktien
Police & Firemen's Retirement System of New Jersey $176.165 73.402 0,02% Aktien
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO $171.426 71.427 0,02% Aktien
PRUDENTIAL FINANCIAL INC $171.228 71.345 0,02% Aktien
MANUFACTURERS LIFE INSURANCE COMPANY, THE $167.393 69.747 0,02% Aktien
NEW YORK STATE COMMON RETIREMENT FUND $164.160 68.400 0,02% Aktien
TWO SIGMA SECURITIES, LLC $159.300 66.375 0,02% Aktien
SEI INVESTMENTS CO $153.449 63.937 0,02% Aktien
Nuveen, LLC $153.449 63.937 0,02% Aktien
Straight Path Wealth Management $150.398 62.666 0,02% Aktien
WELLINGTON MANAGEMENT GROUP LLP $144.000 60.000 0,02% Aktien
R Squared Ltd $131.964 54.985 0,02% Aktien
Vanguard Personalized Indexing Management, LLC $130.402 54.334 0,02% Aktien
Fortis Group Advisors, LLC $120.000 50.000 0,02% Aktien
Schonfeld Strategic Advisors LLC $118.642 49.435 0,02% Aktien
SCOTIA CAPITAL INC. $117.291 48.871 0,02% Aktien
PROFUND ADVISORS LLC $116.606 48.586 0,02% Aktien
VOYA INVESTMENT MANAGEMENT LLC $114.650 47.771 0,02% Aktien
AXQ CAPITAL, LP $109.745 45.727 0,01% Aktien
BOOTHBAY FUND MANAGEMENT, LLC $106.356 44.315 0,01% Aktien
ALLIANCEBERNSTEIN L.P. $105.768 67.800 0,01% Aktien
WINTON GROUP Ltd $103.680 43.200 0,01% Aktien
INTECH INVESTMENT MANAGEMENT LLC $101.978 42.491 0,01% Aktien
LMR Partners LLP $98.618 41.091 0,01% Aktien
BANK OF MONTREAL /CAN/ $96.000 40.000 0,01% Aktien
NORTHERN TRUST CORP $93.794 39.081 0,01% Aktien
BNP PARIBAS FINANCIAL MARKETS $90.672 37.780 0,01% Aktien
Cubist Systematic Strategies, LLC $85.704 63.484 0,01% Aktien
Rafferty Asset Management, LLC $81.816 34.090 0,01% Aktien
ProShare Advisors LLC $78.212 32.588 0,01% Aktien
Leonteq Securities AG $72.000 30.000 0,01% Aktien
PINNACLE ASSOCIATES LTD $69.636 29.015 0,01% Aktien
VICTORY CAPITAL MANAGEMENT INC $58.135 24.223 0,01% Aktien
Legal & General Group Plc $58.044 24.185 0,01% Aktien
XPONANCE LLC $57.031 23.763 0,01% Aktien
Graham Capital Management, L.P. $56.498 23.541 0,01% Aktien
D. E. Shaw & Co., Inc. $53.280 22.200 0,01% Aktien
Quadrature Capital Ltd $52.795 21.998 0,01% Aktien
Invera Wealth Advisors, LLC $48.000 20.000 0,01% Aktien
DIKER MANAGEMENT LLC $48.000 20.000 0,01% Aktien
TIAA-CREF INDIVIDUAL & INSTITUTIONAL SERVICES, LLC $48.000 20.000 0,01% Aktien
Russell Investments Group, Ltd. $47.764 19.902 0,01% Aktien
Point72 Asia (Singapore) Pte. Ltd. $47.282 35.024 0,01% Aktien
Tower Research Capital LLC (TRC) $46.764 19.485 0,01% Aktien
KWB Wealth $46.736 40.640 0,01% Aktien
SBI Securities Co., Ltd. $46.092 19.205 0,01% Aktien
PRINCIPAL FINANCIAL GROUP INC $45.682 19.034 0,01% Aktien
CREDIT AGRICOLE S A $45.540 18.975 0,01% Aktien
WOLVERINE TRADING, LLC $43.785 31.500 0,01% Verkaufsoption
SUSQUEHANNA INTERNATIONAL GROUP, LLP $42.960 17.900 0,01% Verkaufsoption

Unternehmensinsider 49 Insider · 32 Führungskräfte · 19 Direktoren

Insider Rolle Letzte Aktivität Gehaltene Aktien Käufe 12m Verkäufe 12m Netto 12m
Michael Exton Chief Executive Officer 28. Februar 2026 M 298.432 0 0 $0
Lonnel Coats Chief Executive Officer 28. Februar 2024 M 1.098.068 0 0 $0
Arthur T Sands President & CEO 28. Februar 2014 M 1.021.329 0 0 $0
Scott M Coiante SVP, Chief Financial Officer 28. Februar 2026 M 105.356 0 0 $0
Ajay Bansal EVP Corp Dev and CFO 2. Juni 2009 A 0 0 $0
Julia P Gregory EVP and CFO 7. Februar 2008 A 50.200 0 0 $0
Jeffrey L Wade President and COO 8. Juli 2024 A 324.214 0 0 $0
Rachel Yap Martens SVP, Partnerships & Corp Strat 28. Februar 2026 M 31.264 0 0 $0
Suma Gopinathan SVP, Discovery 28. Februar 2026 M 150.132 0 0 $0
Wendy Mcdermott SVP, Human Resources 28. Februar 2026 M 277.945 0 0 $0
Craig B Granowitz SVP, Chief Medical Officer 28. Februar 2026 M 323.430 0 0 $0
Lisa Defrancesco SVP, IR and Corp Comm 28. Februar 2026 M 93.869 0 0 $0
Brian T Crum SVP, General Counsel & Secr. 28. Februar 2026 M 428.802 0 0 $0
Kristen Alexander VP, Finance and Accounting 28. Februar 2025 M 76.368 0 0 $0
Alan J Main EVP, Innov & Chem Sciences 28. Februar 2025 M 339.104 0 0 $0
Brian Corrigan SVP, Regulatory & QA 13. Februar 2025 A 0 0 $0
Kenneth B. Kassler-Taub SVP, Regulatory & QA 28. Februar 2024 M 162.672 0 0 $0
Thomas Garner SVP, Chief Commercial Officer 8. Februar 2024 A 0 0 $0
Kiernan Seth VP, Chief Commercial Officer 28. Februar 2023 M 53.136 0 0 $0
James F Tessmer VP, Finance & Accounting 15. März 2021 M 71.766 0 0 $0
Alexander A Santini EVP and CCO 22. April 2020 F 55.584 0 0 $0
Pablo Lapuerta EVP and CMO 22. April 2020 F 85.719 0 0 $0
John Northcott VP, Marketing, Comm Strategy 2. März 2015 M 8.235 0 0 $0
Brian P Zambrowicz EVP, Chief Scientific Officer 28. Februar 2014 M 278.703 0 0 $0
Steven Alan Tragash VP, Corporate Affairs 15. Februar 2010 A 0 0 $0
Philip M Brown SVP, Clinical Development 15. Februar 2010 A 27.306 0 0 $0
James R Piggott PHD SVP of Pharm Bio 7. Februar 2008 A 0 0 0 $0
Lance K Ishimoto SVP, Intellectual Property 7. Februar 2008 A 10.200 0 0 $0
Tamar D Howson EVP of Bus Dev 7. Februar 2008 A 0 0 $0
Walter F Colbert SVP, HR and Corp Serv 13. Februar 2007 A 0 0 $0
Randall B Riggs SVP, Corp Licensing 23. Februar 2004 M 15.000 0 0 $0
Christophe Person VP Informatics 12. Januar 2004 M 0 0 0 $0
Ivan Cheung Direktor 3. Juni 2026 M 89.312 0 0 $0
Diane E. Sullivan Direktor 3. Juni 2026 M 126.122 0 0 $0
Judith L Swain Direktor 3. Juni 2026 M 174.486 0 0 $0
Amouyal Philippe Direktor 3. Juni 2026 M 374.486 0 0 $0
Sam L Barker Direktor 3. Juni 2026 M 213.771 0 0 $0
Christopher J Sobecki Direktor 3. Juni 2026 M 293.177 0 0 $0
Raymond Debbane Direktor 3. Juni 2026 M 1.995.498 7 0 $723.048
Robert J Lefkowitz MD Direktor 13. Mai 2024 A 48.364 0 0 $0
Frank Palantoni Direktor 21. Mai 2023 M 40.332 0 0 $0
Alan S Nies Direktor 21. Mai 2023 M 41.046 0 0 $0
Invus C.V. Direktor 31. Dezember 2020 J 0 0 0 $0
Kathleen M Wiltsey Direktor 24. April 2009 A 0 0 $0
Clayton Stuart Rose Direktor 26. Juni 2007 P 25.000 0 0 $0
Barry Mills Direktor 26. April 2007 A 25.000 0 0 $0
Patricia M Cloherty Direktor 27. April 2006 A 0 0 $0
Thomas C Caskey Direktor 13. Oktober 2005 P 6.300 0 0 $0
Praveen Tyle 28. Februar 2021 M 120.791 0 0 $0

Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten

Aktivisten & 5%+-Eigentümer 11 Beteiligungen

Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.

Anmelder Eingereicht Beteiligung Status Zweck Einreichung
Invus, L.P., Invus Advisors, L.L.C., Invus Public Equities, L.P., Invus Public Equities Advisors, LLC, Invus Global Management, LLC, Siren, L.L.C., Avicenna Life Sci Master Fund LP, Avicenna Life Sci Master GP LLC, Invus US Partners LLC, Ulys, L.L.C., Raymond Debbane, Artal Participations S.a r.l., Artal International S.C.A., Artal International Management S.A., Artal Group S.A., Westend S.A., Stichting Administratiekantoor Westend, Amaury Wittouck ×7 Einreichungen 8. Mai 2026 39,40% Änderung SEC
Invus, L.P. (2), Invus Advisors, L.L.C. (2), Invus Public Equities, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Global Management, LLC (2), Siren, L.L.C. (2), Artal Participations S.à r.l. (2), Artal International S.C.A. (2), Artal International Management S.A. (2), Artal Group S.A. (2), Westend S.A. (2), Stichting Administratiekantoor Westend (2), Mr. Amaury Wittouck (2), Invus US Partners LLC (2), Ulys, L.L.C. (2), Mr. Raymond Debbane (2) ×15 Einreichungen 9. Dezember 2024 Erste Einreichung SEC
24. Februar 2012 Erste Einreichung SEC
Raymond Debbane (2), Ulys, L.L.C. (2), Invus Advisors, L.L.C. (2), Invus, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Public Equities, L.P. (2), Invus C.V. (2) 27. Dezember 2011 Erste Einreichung SEC
14. November 2011 Erste Einreichung SEC
15. August 2011 Erste Einreichung SEC
Raymond Debbane, Ulys, L.L.C., Invus Advisors, L.L.C., Invus, L.P., Invus Public Equities Advisors, LLC, Invus Public Equities, L.P., Invus C.V. 19. März 2010 Erste Einreichung Kapitalstruktur SEC
Estate of Gordon A. Cain (, Mary H. Cain ×4 Einreichungen 5. August 2005 Erste Einreichung SEC
Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter 8. August 2003 Erste Einreichung SEC
Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter 18. Juli 2003 Erste Einreichung Passive Anlage SEC
Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter 19. März 2003 Erste Einreichung SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF-Besitz Gehalten von 14 ETFs

Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.

Fonds Gewicht Anteile Stand Quelle
QQQS · Invesco Exchange-Traded Fund Trust … 0,56% 51.356 SH 8. August 2026 Täglich
IWC · iShares Trust 0,13% 841.693 SH 8. August 2026 Täglich
VTWG · VANGUARD SCOTTSDALE FUNDS 0,04% 266.401 SH 8. August 2026 Täglich
IWO · iShares Trust 0,04% 2.223.001 SH 8. August 2026 Täglich
PRFZ · Invesco Exchange-Traded Fund Trust 0,03% 323.271 SH 8. August 2026 Täglich
VTWO · VANGUARD SCOTTSDALE FUNDS 0,02% 1.432.882 SH 8. August 2026 Täglich
IWM · iShares Trust 0,02% 6.194.737 SH 8. August 2026 Täglich
VXF · VANGUARD INDEX FUNDS 0,01% 2.594.934 SH 8. August 2026 Täglich
VHT · VANGUARD WORLD FUND 0,01% 637.561 SH 8. August 2026 Täglich
SCHA · SCHWAB STRATEGIC TRUST 0,01% 1.032.223 NS 31. Mai 2026 N-PORT
IWV · iShares Trust 0,00% 84.479 SH 8. August 2026 Täglich
SCHB · SCHWAB STRATEGIC TRUST 0,00% 110.085 NS 31. Mai 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0,00% 7.083.651 SH 8. August 2026 Täglich
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 20.905 SH 8. August 2026 Täglich