LXRX Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne

03
Kurs $1.82
Marktkapitalisierung (MRQ) $813M
P/E (TTM) -12.1
EPS (TTM) $-0.15
Umsatz (TTM) $41M
ROE (TTM) -40.2%
Verschuldungsgrad (MRQ) 0.3
52W-Spanne $1–$3

LXRX Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen

04
Spanne
Balken

Die Balkengranularität passt sich der ausgewählten Periode an – bewegen Sie den Mauszeiger über das Diagramm, um Eröffnungs-/Höchst-/Tiefst-/Schlusskurse für einen Balken anzuzeigen.

Aktiensplits 1
Ex-Datum Split Typ
21. Mai 2015 1-for-7 Umgekehrt

Über Lexicon Pharmaceuticals, Inc. - Common Stock Unternehmensübersicht von Wikipedia

05 · wikidata

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 100 potential therapeutic targets. Lexicon has advanced multiple drug candidates into human clinical trials and has a broad and diverse pipeline of drug targets behind its clinical programs. Lexicon is pursuing drug targets in five therapeutic areas including oncology, gastroenterology, immunology, metabolism, and ophthalmology.

The company's clinical drug candidates include sotagliflozin (LX4211) for the treatment of type 2 diabetes; LX1033 for the treatment of irritable bowel syndrome and other gastrointestinal disorders; telotristat ethyl (LX1032) for the treatment of the symptoms associated with carcinoid syndrome; and LX2931 for the treatment of autoimmune diseases, such as rheumatoid arthritis.

Company history

Lexicon Pharmaceuticals was founded in September 1995 as a biotech venture of Baylor College of Medicine. The company went public in April 2000 with $220 million initial public offerings. In June, 2001 Lexicon purchased a privately owned small chemical library synthesis company, Coelacanth Corporation in Princeton, New Jersey, which became the site for the company's small molecule and medicinal chemistry efforts. The company's original name was Lexicon Genetics Incorporated, but in 2007, the name changed to Lexicon Pharmaceuticals, Inc. to reflect a renewed focus on drug development.

The company initially focused on using gene knockout technology to define the function of genes. This effort complemented and benefited from the international effort to sequence the human and mouse genomes (see Human Genome Project). Using its proprietary gene trapping and gene targeting technologies, the company created A repository of genetically modified mouse embryonic stem cells, known as OmniBank, and established a large-scale mammalian knockout program to discover the physiological and behavioral functions of the most druggable mammalian genes. The information collected from this program is stored in the company's LexVision database, which contains almost 5,000 gene knockouts studied. Over the years, Lexicon evolved from a genomics company into a drug discovery and development company focused on discovering and developing treatments for human disease. The company currently has multiple drug candidates in various stages of clinical trials.

In 2016, the company was ranked #8 on the Deloitte Fast 500 North America list.

Technology

Lexicon uses patented gene trapping and gene targeting technologies to generate and study knockout mice to discover the physiological and behavioral effects that result from the disruption of a single gene knockout. Because there is a close similarity in gene function and physiology between mice and humans, with a large majority of human genes having a counterpart in the mouse genome, knockout mouse technology has become a powerful tool in the discovery of new medicines.

The value of Lexicon's technology in drug discovery has been described in a retrospective analysis by the scientific journal Nature. The conclusion of this analysis was that, in most cases, there was a direct correlation when comparing the physiological characteristics, or phenotypes, of knockout mice to the therapeutic effect of the 100 best-selling drugs of 2001. The tremendous utility of knockout mouse technology was recognized in 2007 with the Nobel Prize in Physiology or Medicine to Drs. Mario Capecchi, Martin Evans, and Oliver Smithies.

In developing small molecule drugs for its validated targets, Lexicon uses medicinal chemistry known as "click chemistry." Dr. K. Barry Sharpless, who was awarded the 2001 Nobel Prize in Chemistry, developed this tools for the rapid synthesis of novel compounds. Lexicon uses solution-phase chemistry to generate diverse libraries of optically pure compounds that are built using organic reactions that allow the company to generate collections of different compounds and to tailor the compound collections to address various therapeutic target families. Lexicon's medicinal chemists design these libraries by analyzing the chemical structures of drugs that have been proven safe and effective against human disease and using that knowledge in the design of scaffolds and chemical building blocks for the generation of large numbers of new drug-like compounds.

Locations

Lexicon operates from two locations found in Texas and New Jersey. The corporate headquarters are in The Woodlands, Texas just north of Houston. This location serves as Lexicon's primary research facility to discover and validate the company's drug targets and test drug candidates in preclinical research. The company's clinical development and regulatory team is also based at the corporate headquarters.

Lexicon's campus in Princeton, New Jersey is the home of Lexicon's small molecule medicinal chemistry and preclinical development efforts. This site serves as Lexicon's primary medicinal chemistry site to create new chemical entities for therapeutic development.

== References ==

Quelle: Wikipedia (Englisch), CC BY-SA 4.0 · Auf Wikipedia ansehen ↗

Wikidata ↗

SektorHealthcare BranchePharmaceuticals Mitarbeiter81 LandUS

10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends

06
Umsatz$50M
2016-12-31 → 2025-12-31
EPS$-0.14
2017-12-31 → 2025-12-31
Freier Cashflow$-68M
2016-12-31 → 2025-12-31
Nettogewinnmarge-147.4%
2016-12-31 → 2025-12-31
Bewertung & Kennzahlen 07–12

Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?

Kennzahl 5-Jahres-Trend LXRX 5-Jahres-Durchschnitt Peer-Median Fazit
P/E (TTM) -12.15-Jahres-Durchschnitt ≈-4.2 ≈-4.2 · ·
P/S (TTM) 19.65-Jahres-Durchschnitt ≈1530.9 ≈1530.9 6.6 Überbewertet
K/B (MRQ) 4.75-Jahres-Durchschnitt ≈4.1 ≈4.1 3.8 Überbewertet
EV / EBITDA (TTM) -12.5 · · ·
Price / FCF (Kurs / FCF) -9.85-Jahres-Durchschnitt ≈-5.6 ≈-5.6 · ·
Price / Cash Flow (Kurs / Cashflow) -9.85-Jahres-Durchschnitt ≈-5.7 ≈-5.7 · ·
EV / Umsatz (TTM) 16.3 · · ·
EV / FCF -9.2 · · ·
Price / Tangible Book (Kurs / Materieller Buchwert) 10.65-Jahres-Durchschnitt ≈6.7 ≈6.7 · ·

Der Median der Vergleichsgruppe wird pro Kennzahl standardisiert berechnet und stimmt möglicherweise nicht immer mit der für diese Aktie angezeigten TTM/MRQ-Basis überein.

Wert · ≈ 5-Jahres-Durchschnitt · Branchenmedian · Urteil relativ zum Median

Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum

14
Durchschn. Überraschung 48.2%
Nächster Bericht Nov 13, 2026
ZeitraumBerichtEPS ActualEPS est.Überraschung
30. Juni 2026 Aug 4, 2026 $-0.07 $-0.05 -36.7%
31. März 2026 Mai 11, 2026 $0.00 $-0.04 100.0%
31. Dezember 2025 $-0.04 $-0.07 43.2%
30. September 2025 $-0.04 $-0.07 40.6%
30. Juni 2025 $0.01 $-0.08 112.6%
31. März 2025 $-0.07 $-0.10 29.6%

Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow

15
Gewinn- und Verlustrechnung 16
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue $50M$31M$1M$139.0K$298.0K$24M$322M$63M$92M$79M$130M$23M
Cost of Revenue $274.0K$616.0K$85.0K$0$0$2M$3M$2M$2M$0$0·
R&D Expense $61M$84M$59M$53M$55M$154M$92M$100M$152M$164M$95M$89M
SG&A Expense $37M$143M$114M$48M$32M$47M$57M$64M$66M$43M$24M$19M
Operating Expenses $99M$228M$173M$101M$87M$204M$181M$166M$222M$206M$129M$123M
Operating Income $-49M$-197M$-172M$-101M$-87M$-48M$141M$-103M$-131M$-127M$1M$-100M
Interest Expense ···$3M$802.0K$15M$21M$21M$7M$7M$7M$2M
Other Non-op $7M$12M$8M$2M$134.0K$3M$3M$4M$2M$2M$572.0K$2M
Pretax Income ····$-88M$-59M$124M$-121M$-136M$-131M$-5M$-100M
Income Tax ·$0$0$0$0····$0$0$-70.0K
Net Income $-50M$-200M$-177M$-102M$-88M$-59M$130M$-121M$-123M$-131M$-5M$-100M
EPS (Basic) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.23$-1.14$-1.17···
EPS (Diluted) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.16$-1.14$-1.17···
Shares (Basic) 363,053,000320,031,000221,130,000165,733,000145,652,000·······
Shares (Diluted) 363,053,000320,031,000221,130,000165,733,000145,652,000110,841,000116,747,000105,830,000105,237,000···
EBITDA $-48M$-197M$-171M$-100M$-87M$-45M$145M$-100M$-133M$-135M·$-98M
Bilanz 30
Kennzahl Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $34M$67M$22M$46M$64M$126M$36M$80M$62M$47M$203M$137M
Short-term Investments $62M$171M$148M$92M$23M$26M$236M$80M$249M$300M$318M$202M
Receivables $2M$3M$1M$28.0K$14.0K$395.0K$57M$6M$5M$7M$911.0K$1M
Inventory $281.0K$231.0K$381.0K$0·$0$4M$5M$2M$0··
Other Current Assets $3M$5M$5M$2M$2M$5M$5M$3M$4M$4M$10M$5M
Current Assets $102M$246M$177M$141M$89M$158M$338M$173M$322M$358M$532M$369M
PP&E (Net) $2M$2M$2M$2M$1M$295.0K$14M$16M$18M$19M$21M$1M
PP&E (Gross) $5M$5M$7M$6M$6M$6M$76M$76M$76M$79M$81M$37M
Accum. Depreciation $3M$2M$5M$4M$5M$6M$62M$60M$59M$60M$59M$36M
Goodwill $45M$45M$45M$45M$45M$45M$45M$45M$45M$45M$45M$45M
Intangibles ······$20M$50M$52M$53M$53M$53M
Other Non-current Assets $368.0K$368.0K$828.0K$412.0K$2M$1M$2M$285.0K$429.0K$461.0K$433.0K$3M
Total Assets $185M$298M$229M$194M$137M$204M$418M$284M$437M$476M$652M$471M
Accounts Payable $3M$15M$14M$10M$9M$5M$12M$12M$39M$53M$20M$13M
Accrued Liabilities $13M$30M$17M$13M$13M$30M$42M$21M$12M$32M$25M$10M
Current Liabilities $21M$45M$32M$23M$22M$47M$65M$37M$105M$165M$123M$45M
Capital Leases $7M$5M$5M$5M········
Deferred Tax ······$0$6M$6M$19M$19M$19M
Other Non-current Liabilities $7M$7M$5M$5M$1M$611.0K$1M$238.0K$292.0K$805.0K$14M$24M
Total Liabilities $77M$152M$136M$77M$23M$47M$301M$311M$368M$318M$366M$187M
Long-term Debt $54M$100M·$49M$0$12M$249M$250M$252M$101M$106M$108M
Total Debt $54M$100M$100M·$0$12M$245M$245M$246M$101M·$108M
Common Stock $366.0K$363.0K$245.0K$189.0K$150.0K$142.0K$106.0K$106.0K$106.0K$105.0K$104.0K$104.0K
Paid-in Capital $2.13B$2.12B$1.86B$1.71B$1.61B$1.56B$1.46B$1.45B$1.44B$1.41B$1.40B$1.39B
Retained Earnings $-2.02B$-1.97B$-1.77B$-1.59B$-1.49B$-1.40B$-1.34B$-1.47B$-1.37B$-1.25B$-1.11B$-1.10B
Treasury Stock $5M$5M$3M$2M$8M$5M$4M$3M$2M$3M$3M$2M
AOCI $30.0K$119.0K$31.0K$-428.0K$-10.0K$-6.0K$84.0K$-12.0K$-222.0K$-195.0K$-219.0K$-63.0K
Stockholders' Equity $108M$146M$93M$117M$114M$156M$117M$-26M$68M$168M$286M$284M
Liabilities + Equity $185M$298M$229M$194M$137M$204M$418M$284M$437M$476M$652M$471M
Shares Outstanding 365,848,216363,020,303·189,214,000150,082,000142,289,000106,679,000106,162,000105,711,000104,582,000103,860,000103,663,000
Cashflow 17
Kennzahl Trend 202520242023202220212020201920182017201620152014
D&A $621.0K$534.0K$554.0K$427.0K$292.0K$3M$4M$4M$3M$2M$727.0K$2M
Stock-based Comp $13M$13M$14M$12M$11M$13M$14M$12M$9M$7M$7M$7M
Deferred Tax ···$0$0$0$-6M$0$-13M$0$0$-70.0K
Amort. of Intangibles ·······$2M$2M···
Other Non-cash $-31M$8M$328.0K$1M$-10M$-101M$-28M$-43M$-57M$-44M·$16M
Operating Cash Flow $-68M$-179M$-162M$-89M$-87M$-143M$114M$-149M$-185M$-176M$185M$-76M
CapEx $0$1M$470.0K$1M$1M$87.0K$70.0K$95.0K$228.0K$231.0K$910.0K$80.0K
Investing Cash Flow $113M$-15M$-50M$-71M$2M$381M$-156M$170M$51M$18M$-117M$-108M
Debt Issued $0$0$50M$49M·$0$0$13M$146M$0$0$84M
Net Debt Issued $0$0·$49M$-12M$-217M$-1M$-2M$144M$-2M·$82M
Stock Issued $0$0$139M$94M$37M$70M$0$732.0K$8M$4M$114.0K$202M
Stock Repurchased ·$2M$824.0K$864.0K$3M$1M$941.0K$972.0K$2M$621.0K$357.0K$887.0K
Net Stock Activity $0$-2M$138M$93M$34M$69M$-941.0K$-240.0K$6M$3M·$201M
Financing Cash Flow $-48M$238M$188M$142M$23M$-148M$-2M$-2M$150M$987.0K$-2M$284M
Net Change in Cash $-3M$44M$-24M$-18M$-62M$90M$-44M$19M$15M$-156M$66M$100M
Free Cash Flow $-68M$-180M$-162M$-90M$-88M$-143M$114M$-149M$-186M$-176M·$-76M
Levered FCF ·········$-182M·$-78M
Rentabilität 7
Kennzahl Trend 202520242023202220212020201920182017201620152014
Operating Margin -98.2%-634.2%-14264.9%-72489.2%-29224.8%-199.2%43.9%-163.4%-151.3%-164.6%·-439.2%
Net Margin -101.1%-644.8%-14710.9%-73341.0%-29449.0%-244.1%40.4%-190.7%-142.9%-169.7%·-438.8%
Pretax Margin ····-29449.0%-244.1%38.5%-190.7%-156.9%-169.7%·-439.1%
EBITDA Margin -97.0%-632.5%-14218.9%-72182.0%-29126.9%-187.0%45.1%-157.6%-147.5%-162.1%·-430.7%
ROA -20.8%-75.9%-83.6%-61.6%-51.5%-18.9%37.1%-33.5%-28.3%-25.1%·-26.9%
ROE -39.7%-167.7%-168.5%-88.4%-65.0%-42.8%287.0%-576.0%-117.5%-63.8%·-44.2%
ROIC ·········-53.0%·-25.6%
Liquidität & Solvenz 5
Kennzahl Trend 202520242023202220212020201920182017201620152014
Current Ratio 4.95.45.66.14.03.45.24.72.62.2·8.2
Quick Ratio 4.75.35.46.03.93.35.04.52.52.2·7.6
Debt / Equity 0.50.71.1·0.00.12.1-9.34.70.6·0.4
LT Debt / Equity 0.50.71.1··0.02.0-9.24.40.5·0.3
Interest Coverage ···-36.2-108.6-3.36.8-5.0-19.6-20.9·-44.5
Effizienz 3
Kennzahl Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.20.10.00.00.00.10.90.20.20.1·0.1
Inventory Turnover 1.12.00.4··0.90.70.81.9···
Receivables Turnover 17.013.92.36.61.50.810.311.814.719.8·25.0
Pro Aktie 5
Kennzahl Trend 202520242023202220212020201920182017201620152014
Book Value / Share $0.29··$0.62$0.76$1.10$1.10$-0.25$0.49$1.50·$0.39
Revenue / Share $0.14$0.10$0.01·$0.00$0.22$2.76·····
Cash Flow / Share $-0.19$-0.56$-0.73·$-0.60$-1.29$0.97·····
Cash / Share $0.09··$0.24$0.43$0.89$0.34$0.76$0.58$0.45·$0.19
EPS (TTM) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.16$-1.14$-1.17$-0.12$-0.12·
Wachstumsraten 3
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue YoY 60.2%2481.5%766.2%-53.4%-98.8%·······
Revenue CAGR 3Y 610.2%370.7%-63.1%·········
Revenue CAGR 5Y 15.7%···········
Bewertung (TTM) 14
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue TTM $50M$31M$1M$139.0K$298.0K$24M$322M$63M$92M$79M$130M$23M
Net Income TTM $-50M$-200M$-177M$-102M$-88M$-59M$130M$-121M$-123M$-131M$-5M$-100M
Market Cap $421M··$361M$591M$487M$443M$705M$1.04B$1.45B·$4.62B
Enterprise Value $378M···$505M$346M$416M$790M$979M$1.20B·$4.39B
P/E -8.2-1.2-1.9-3.1-6.6-6.53.6-5.8-8.4-115.2-110.9·
P/S 8.4··2600.01984.320.31.411.211.418.2·202.3
P/B 3.9··3.15.23.13.8-26.720.09.2·16.3
P / Tangible Book 6.7··5.08.64.4······
P / Cash Flow -6.2··-4.1-6.8-3.43.9-4.7-5.6-8.2·-61.1
P / FCF -6.2··-4.0-6.7-3.43.9-4.7-5.6-8.2·-61.1
EV / EBITDA -7.8···-5.8-7.72.9-7.9-7.3-8.9·-44.6
EV / FCF -5.6···-5.7-2.43.7-5.3-5.3-6.8·-58.0
EV / Revenue 7.6···1693.214.41.312.510.715.2·192.1
Earnings Yield -12.2%-85.1%-52.3%-32.5%-15.2%-15.5%28.0%-17.2%-11.8%-0.87%-0.90%·

Aktuellster Zeitraum links · fehlende Werte werden als · angezeigt

Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre

16
Kennzahl 2025-12-312024-12-312023-12-312022-12-312021-12-31
Umsatz $50M $31M $1M $139.0K $298.0K
Betriebsgewinnmarge % -98.2% -634.2% -14264.9% -72489.2% -29224.8%
Nettoergebnis $-50M $-200M $-177M $-102M $-88M
Verwässerte EPS $-0.14 $-0.63 $-0.80 $-0.62 $-0.60

Institutionelle Eigentümer (13F) 167 Einreicher · $890.0M gesamt · Stand 30. Juni 2026

17

Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.

Inhaber 167
Gehaltener Wert $890.0M
Neue Positionen 43
Geschlossene Positionen 27
Institutionelle Aktivität — Q2 2026 vs. Vorquartal
Neue Positionen Geschlossene Positionen Erhöht Abgenommen Nettoveränderung der Aktien
43 (+9 vs. Vorquartal) 27 (+14 vs. Vorquartal) 39 (-5 vs. Vorquartal) 38 (+14 vs. Vorquartal) +42.4M

Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.

Institution Wert Aktien % der verfolgten 13F Typ
Artal Group S.A. $420.374.549 175.156.062 47,23% Aktien
FMR LLC $124.276.907 51.782.045 13,96% Aktien
Siren, L.L.C. $106.328.443 44.303.518 11,95% Aktien
Sessa Capital IM, L.P. $45.506.006 18.960.836 5,11% Aktien
BlackRock, Inc. $41.636.978 17.348.741 4,68% Aktien
VANGUARD CAPITAL MANAGEMENT LLC $23.762.899 9.901.208 2,67% Aktien
Point72 Asset Management, L.P. $19.803.180 8.251.325 2,23% Aktien
GEODE CAPITAL MANAGEMENT, LLC $14.989.739 6.244.372 1,68% Aktien
STATE STREET CORP $11.802.646 4.917.769 1,33% Aktien
VANGUARD GROUP INC $11.047.532 9.606.549 1,24% Aktien
VANGUARD PORTFOLIO MANAGEMENT LLC $5.658.598 2.357.749 0,64% Aktien
NORTHERN TRUST CORP $4.724.686 1.968.619 0,53% Aktien
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4.696.260 1.956.775 0,53% Aktien
VANGUARD FIDUCIARY TRUST CO $3.922.970 1.634.571 0,44% Aktien
CITADEL ADVISORS LLC $3.842.837 1.601.182 0,43% Aktien
CIBC Private Wealth Group LLC $3.240.347 2.400.257 0,36% Aktien
Ishara Investments LP $3.050.400 1.271.000 0,34% Aktien
MILLENNIUM MANAGEMENT LLC $2.722.150 1.134.229 0,31% Aktien
RENAISSANCE TECHNOLOGIES LLC $2.704.800 1.127.000 0,30% Aktien
MACKENZIE FINANCIAL CORP $2.312.050 963.354 0,26% Aktien
ADAR1 Capital Management, LLC $1.800.000 750.000 0,20% Aktien
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1.672.262 696.776 0,19% Aktien
UBS Group AG $1.643.312 684.713 0,18% Aktien
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1.604.400 668.500 0,18% Kaufoption
TWO SIGMA INVESTMENTS, LP $1.544.266 643.444 0,17% Aktien
Nuveen, LLC $1.407.994 586.664 0,16% Aktien
JANE STREET GROUP, LLC $1.398.960 582.900 0,16% Kaufoption
Bank of New York Mellon Corp $1.364.893 568.706 0,15% Aktien
Invesco Ltd. $1.219.370 508.071 0,14% Aktien
GOLDMAN SACHS GROUP INC $1.165.310 485.546 0,13% Aktien
Compagnie Lombard Odier SCmA $1.152.000 480.000 0,13% Aktien
BANK OF AMERICA CORP /DE/ $1.011.117 421.299 0,11% Aktien
BARCLAYS PLC $929.960 387.483 0,10% Aktien
CITADEL ADVISORS LLC $886.320 369.300 0,10% Kaufoption
XTX Topco Ltd $858.905 357.877 0,10% Aktien
CANADA PENSION PLAN INVESTMENT BOARD $618.960 257.900 0,07% Aktien
RHUMBLINE ADVISERS $616.523 256.885 0,07% Aktien
DEUTSCHE BANK AG\ $594.068 247.528 0,07% Aktien
WELLS FARGO & COMPANY/MN $553.128 230.470 0,06% Aktien
WELLINGTON MANAGEMENT GROUP LLP $431.280 179.700 0,05% Aktien
CITIGROUP INC $420.492 175.205 0,05% Aktien
GROUP ONE TRADING LLC $420.031 175.013 0,05% Aktien
Virtus Investment Advisers, LLC $408.996 170.415 0,05% Aktien
Headlands Technologies LLC $401.275 167.198 0,05% Aktien
Ikarian Capital, LLC $395.218 164.674 0,04% Aktien
Quarry LP $374.846 156.186 0,04% Aktien
MetLife Investment Management, LLC $351.384 146.410 0,04% Aktien
MORGAN STANLEY $318.964 132.902 0,04% Aktien
PANAGORA ASSET MANAGEMENT INC $316.901 132.042 0,04% Aktien
JPMORGAN CHASE & CO $289.975 109.839 0,03% Aktien

Alle 167 institutionellen Eigentümer anzeigen →

Aktivisten & 5%+-Eigentümer 11 Beteiligungen

18

Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.

Anmelder Eingereicht Beteiligung Status Zweck Einreichung
Invus, L.P., Invus Advisors, L.L.C., Invus Public Equities, L.P., Invus Public Equities Advisors, LLC, Invus Global Management, LLC, Siren, L.L.C., Avicenna Life Sci Master Fund LP, Avicenna Life Sci Master GP LLC, Invus US Partners LLC, Ulys, L.L.C., Raymond Debbane, Artal Participations S.a r.l., Artal International S.C.A., Artal International Management S.A., Artal Group S.A., Westend S.A., Stichting Administratiekantoor Westend, Amaury Wittouck ×7 Einreichungen 8. Mai 2026 39,40% Änderung · SEC
Invus, L.P. (2), Invus Advisors, L.L.C. (2), Invus Public Equities, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Global Management, LLC (2), Siren, L.L.C. (2), Artal Participations S.à r.l. (2), Artal International S.C.A. (2), Artal International Management S.A. (2), Artal Group S.A. (2), Westend S.A. (2), Stichting Administratiekantoor Westend (2), Mr. Amaury Wittouck (2), Invus US Partners LLC (2), Ulys, L.L.C. (2), Mr. Raymond Debbane (2) ×15 Einreichungen 9. Dezember 2024 · Erste Einreichung · SEC
24. Februar 2012 · Erste Einreichung · SEC
Raymond Debbane (2), Ulys, L.L.C. (2), Invus Advisors, L.L.C. (2), Invus, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Public Equities, L.P. (2), Invus C.V. (2) 27. Dezember 2011 · Erste Einreichung · SEC
14. November 2011 · Erste Einreichung · SEC
15. August 2011 · Erste Einreichung · SEC
Raymond Debbane, Ulys, L.L.C., Invus Advisors, L.L.C., Invus, L.P., Invus Public Equities Advisors, LLC, Invus Public Equities, L.P., Invus C.V. 19. März 2010 · Erste Einreichung Kapitalstruktur SEC
Estate of Gordon A. Cain (, Mary H. Cain ×4 Einreichungen 5. August 2005 · Erste Einreichung · SEC
Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter 8. August 2003 · Erste Einreichung · SEC
Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter 18. Juli 2003 · Erste Einreichung Passive Anlage SEC
Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter, Nicht offengelegter meldender Beteiligter 19. März 2003 · Erste Einreichung · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Unternehmensinsider 49 Insider · 32 Führungskräfte · 19 Direktoren

19
Insider Rolle Letzte Aktivität Gehaltene Aktien Käufe 12m Verkäufe 12m Netto 12m
Michael Exton Chief Executive Officer 28. Februar 2026 M 298.432 0 0 $0
Lonnel Coats Chief Executive Officer 28. Februar 2024 M 1.098.068 0 0 $0
Arthur T Sands President & CEO 28. Februar 2014 M 1.021.329 0 0 $0
Scott M Coiante SVP, Chief Financial Officer 28. Februar 2026 M 105.356 0 0 $0
Ajay Bansal EVP Corp Dev and CFO 2. Juni 2009 A · 0 0 $0
Julia P Gregory EVP and CFO 7. Februar 2008 A 50.200 0 0 $0
Jeffrey L Wade President and COO 8. Juli 2024 A 324.214 0 0 $0
Rachel Yap Martens SVP, Partnerships & Corp Strat 28. Februar 2026 M 31.264 0 0 $0
Suma Gopinathan SVP, Discovery 28. Februar 2026 M 150.132 0 0 $0
Wendy Mcdermott SVP, Human Resources 28. Februar 2026 M 277.945 0 0 $0
Craig B Granowitz SVP, Chief Medical Officer 28. Februar 2026 M 323.430 0 0 $0
Lisa Defrancesco SVP, IR and Corp Comm 28. Februar 2026 M 93.869 0 0 $0
Brian T Crum SVP, General Counsel & Secr. 28. Februar 2026 M 428.802 0 0 $0
Kristen Alexander VP, Finance and Accounting 28. Februar 2025 M 76.368 0 0 $0
Alan J Main EVP, Innov & Chem Sciences 28. Februar 2025 M 339.104 0 0 $0
Brian Corrigan SVP, Regulatory & QA 13. Februar 2025 A · 0 0 $0
Kenneth B. Kassler-Taub SVP, Regulatory & QA 28. Februar 2024 M 162.672 0 0 $0
Thomas Garner SVP, Chief Commercial Officer 8. Februar 2024 A · 0 0 $0
Kiernan Seth VP, Chief Commercial Officer 28. Februar 2023 M 53.136 0 0 $0
James F Tessmer VP, Finance & Accounting 15. März 2021 M 71.766 0 0 $0
Alexander A Santini EVP and CCO 22. April 2020 F 55.584 0 0 $0
Pablo Lapuerta EVP and CMO 22. April 2020 F 85.719 0 0 $0
John Northcott VP, Marketing, Comm Strategy 2. März 2015 M 8.235 0 0 $0
Brian P Zambrowicz EVP, Chief Scientific Officer 28. Februar 2014 M 278.703 0 0 $0
Steven Alan Tragash VP, Corporate Affairs 15. Februar 2010 A · 0 0 $0
Philip M Brown SVP, Clinical Development 15. Februar 2010 A 27.306 0 0 $0
James R Piggott PHD SVP of Pharm Bio 7. Februar 2008 A 0 0 0 $0
Lance K Ishimoto SVP, Intellectual Property 7. Februar 2008 A 10.200 0 0 $0
Tamar D Howson EVP of Bus Dev 7. Februar 2008 A · 0 0 $0
Walter F Colbert SVP, HR and Corp Serv 13. Februar 2007 A · 0 0 $0
Randall B Riggs SVP, Corp Licensing 23. Februar 2004 M 15.000 0 0 $0
Christophe Person VP Informatics 12. Januar 2004 M 0 0 0 $0
Ivan Cheung Direktor 3. Juni 2026 M 89.312 0 0 $0
Diane E. Sullivan Direktor 3. Juni 2026 M 126.122 0 0 $0
Judith L Swain Direktor 3. Juni 2026 M 174.486 0 0 $0
Amouyal Philippe Direktor 3. Juni 2026 M 374.486 0 0 $0
Sam L Barker Direktor 3. Juni 2026 M 213.771 0 0 $0
Christopher J Sobecki Direktor 3. Juni 2026 M 293.177 0 0 $0
Raymond Debbane Direktor 3. Juni 2026 M 1.995.498 7 0 $723.048
Robert J Lefkowitz MD Direktor 13. Mai 2024 A 48.364 0 0 $0
Frank Palantoni Direktor 21. Mai 2023 M 40.332 0 0 $0
Alan S Nies Direktor 21. Mai 2023 M 41.046 0 0 $0
Invus C.V. Direktor 31. Dezember 2020 J 0 0 0 $0
Kathleen M Wiltsey Direktor 24. April 2009 A · 0 0 $0
Clayton Stuart Rose Direktor 26. Juni 2007 P 25.000 0 0 $0
Barry Mills Direktor 26. April 2007 A 25.000 0 0 $0
Patricia M Cloherty Direktor 27. April 2006 A · 0 0 $0
Thomas C Caskey Direktor 13. Oktober 2005 P 6.300 0 0 $0
Praveen Tyle · 28. Februar 2021 M 120.791 0 0 $0

Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten

ETF-Besitz Gehalten von 16 ETFs

20

Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.

Fonds Gewicht Anteile Stand Quelle
BBC · ETFis Series Trust I 0,81% 161.882 NS 31. Juli 2026 N-PORT
PILL · Direxion Shares ETF Trust 0,45% 40.310 NS 31. Juli 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0,42% 53.319 SH 2. Oktober 2026 Täglich
IWC · iShares Trust 0,12% 842.323 SH 11. September 2026 Täglich
VTWG · VANGUARD SCOTTSDALE FUNDS 0,04% 266.401 SH 19. August 2026 Täglich
IWO · iShares Trust 0,03% 2.343.443 SH 11. September 2026 Täglich
VTWO · VANGUARD SCOTTSDALE FUNDS 0,02% 1.432.882 SH 19. August 2026 Täglich
RSSL · Global X Funds 0,02% 118.391 NS 31. Juli 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0,02% 255.130 SH 2. Oktober 2026 Täglich
IWM · iShares Trust 0,02% 6.319.224 SH 11. September 2026 Täglich
VXF · VANGUARD INDEX FUNDS 0,01% 2.594.934 SH 19. August 2026 Täglich
VHT · VANGUARD WORLD FUND 0,01% 637.561 SH 19. August 2026 Täglich
WSML · iShares Trust 0,01% 17.992 SH 11. September 2026 Täglich
IWV · iShares Trust 0,00% 85.389 SH 3. September 2026 Täglich
VTI · VANGUARD INDEX FUNDS 0,00% 7.083.651 SH 19. August 2026 Täglich
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 20.905 SH 19. August 2026 Täglich

LXRX Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial

21
Bewertung · 11 Analysten KAUF
Median-Ziel $4.55 +150,0%
3 27,3% Starker Kauf
5 45,5% Kauf
3 27,3% Halten
0 0,0% Verkauf
0 0,0% Starker Verkauf

12-Monats-Kursziel

6 Analysten · 2026-09-30

Mittelwert-Ziel $4.55 +149,8%

← Unter allen Zielen Aktueller Preis $1.82
Tief$2.00 Mittelwert$4.55 Hoch$8.00

Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen

22

FY-Basis, Kurse zum Schlusskurs am Ende des letzten Geschäftsjahres jedes Unternehmens.

Ticker Marktkapitalisierung P/E Umsatz Vj. Nettomarge ROE Bruttogewinnmarge
LXRX $421M -8.2 60.2% -101.1% -39.7% ·
ANRO $568M -8.1 · · -46.1% ·
ALMS · -3.4 · -1011.8% -61.9% ·
APMD · · · · · ·
SGP · · · · 50.0% ·
COLL $1.47B 26.8 23.6% 8.1% 23.5% 59.4%
ACRS $363M -5.7 -58.2% -829.6% -55.3% ·
ZVRA $509M 6.6 350.9% 78.2% 61.2% ·
AQST $788M -8.3 -22.6% -188.1% 157.7% ·
PHAT $1.18B -5.5 216.9% -126.4% 52.4% 87.1%

Neueste Nachrichten Aktuelle Schlagzeilen über dieses Unternehmen

23

Meine Kennzahlen Ihre persönliche Watchlist — ausgewählte Zeilen aus den vollständigen Fundamentaldaten

26

Wählen Sie die Kennzahlen, die für Sie wichtig sind — klicken Sie auf das + neben jeder Zeile in den vollständigen Fundamentaldaten oben.

Ihre Auswahl wird gespeichert und begleitet Sie über alle Ticker hinweg.

Quelle: SEC 10-Q eingereicht Aug 6, 2026