NAMS — Institutionelle Eigentümer (13F)
Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.
| Institution | Wert | Aktien | % der verfolgten 13F | Typ |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $613.032.889 | 18.088.902 | 15,23% | Aktien |
| Capital World Investors | $414.493.577 | 12.230.557 | 10,30% | Aktien |
| FMR LLC | $350.411.179 | 10.339.663 | 8,70% | Aktien |
| RA CAPITAL MANAGEMENT, L.P. | $323.655.973 | 9.550.191 | 8,04% | Aktien |
| FCPM III SERVICES B.V. | $287.738.063 | 8.490.353 | 7,15% | Aktien |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $144.533.699 | 4.264.789 | 3,59% | Aktien |
| VIKING GLOBAL INVESTORS LP | $142.458.886 | 4.203.567 | 3,54% | Aktien |
| Bain Capital Life Sciences Investors, LLC | $129.004.522 | 3.806.566 | 3,20% | Aktien |
| MAVERICK CAPITAL LTD | $110.745.810 | 3.267.802 | 2,75% | Aktien |
| Medicxi Ventures Management (Jersey) Ltd | $74.850.776 | 2.208.639 | 1,86% | Aktien |
| JANUS HENDERSON GROUP PLC | $72.253.603 | 2.258.984 | 1,79% | Aktien |
| JENNISON ASSOCIATES LLC | $71.246.471 | 2.102.286 | 1,77% | Aktien |
| Orbis Allan Gray Ltd | $59.227.079 | 1.747.627 | 1,47% | Aktien |
| Polar Capital Holdings Plc | $58.443.915 | 1.724.518 | 1,45% | Aktien |
| Capital International Investors | $58.409.246 | 1.723.495 | 1,45% | Aktien |
| GOLDMAN SACHS GROUP INC | $52.357.034 | 1.544.911 | 1,30% | Aktien |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $52.071.036 | 1.536.472 | 1,29% | Aktien |
| Castle Hook Partners LP | $46.463.359 | 1.371.005 | 1,15% | Aktien |
| AMERIPRISE FINANCIAL INC | $42.482.886 | 1.253.549 | 1,06% | Aktien |
| ALLIANCEBERNSTEIN L.P. | $40.330.679 | 1.259.940 | 1,00% | Aktien |
| JPMORGAN CHASE & CO | $38.373.185 | 1.132.955 | 0,95% | Aktien |
| Aberdeen Group plc | $37.373.384 | 1.102.785 | 0,93% | Aktien |
| BlackRock, Inc. | $36.050.487 | 1.063.750 | 0,90% | Aktien |
| FRANKLIN RESOURCES INC | $33.683.835 | 993.917 | 0,84% | Aktien |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $26.472.835 | 781.140 | 0,66% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $25.564.142 | 754.327 | 0,63% | Aktien |
| Woodline Partners LP | $25.501.852 | 752.489 | 0,63% | Aktien |
| BANK OF AMERICA CORP /DE/ | $24.925.518 | 735.483 | 0,62% | Aktien |
| TimesSquare Capital Management, LLC | $24.071.136 | 751.988 | 0,60% | Aktien |
| AMERICAN CENTURY COMPANIES INC | $23.208.343 | 684.813 | 0,58% | Aktien |
| CITADEL ADVISORS LLC | $21.886.331 | 645.805 | 0,54% | Aktien |
| Jefferies Financial Group Inc. | $20.334.000 | 600.000 | 0,51% | Verkaufsoption |
| Rock Springs Capital Management LP | $19.749.194 | 582.744 | 0,49% | Aktien |
| First Turn Management, LLC | $19.740.823 | 582.497 | 0,49% | Aktien |
| MORGAN STANLEY | $19.514.724 | 575.825 | 0,48% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $19.269.854 | 568.600 | 0,48% | Verkaufsoption |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $18.639.500 | 550.000 | 0,46% | Aktien |
| Artia Global Partners LP | $17.078.391 | 503.936 | 0,42% | Aktien |
| MILLENNIUM MANAGEMENT LLC | $16.999.698 | 501.614 | 0,42% | Aktien |
| PERCEPTIVE ADVISORS LLC | $16.945.000 | 500.000 | 0,42% | Verkaufsoption |
| Cormorant Asset Management, LP | $16.945.000 | 500.000 | 0,42% | Aktien |
| JANE STREET GROUP, LLC | $16.071.858 | 474.236 | 0,40% | Aktien |
| KENNEDY CAPITAL MANAGEMENT LLC | $14.280.365 | 421.374 | 0,35% | Aktien |
| Bank of New York Mellon Corp | $11.973.270 | 353.298 | 0,30% | Aktien |
| UBS Group AG | $11.660.363 | 344.065 | 0,29% | Aktien |
| Slate Path Capital LP | $10.810.910 | 319.000 | 0,27% | Aktien |
| ExodusPoint Capital Management, LP | $10.313.879 | 304.334 | 0,26% | Aktien |
| Eversept Partners, LP | $9.335.712 | 275.471 | 0,23% | Aktien |
| Affinity Asset Advisors, LLC | $9.319.750 | 275.000 | 0,23% | Aktien |
| SEB Asset Management AB | $9.240.226 | 272.654 | 0,23% | Aktien |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $9.131.973 | 285.285 | 0,23% | Aktien |
| Atle Fund Management AB | $8.433.458 | 248.848 | 0,21% | Aktien |
| GILDER GAGNON HOWE & CO LLC | $7.593.732 | 224.070 | 0,19% | Aktien |
| WELLINGTON MANAGEMENT GROUP LLP | $7.413.404 | 218.749 | 0,18% | Aktien |
| LMR Partners LLP | $7.269.405 | 214.500 | 0,18% | Verkaufsoption |
| Ensign Peak Advisors, Inc | $7.199.015 | 212.423 | 0,18% | Aktien |
| ArrowMark Colorado Holdings LLC | $7.179.359 | 211.843 | 0,18% | Aktien |
| DEUTSCHE BANK AG\ | $6.775.662 | 199.931 | 0,17% | Aktien |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $6.156.932 | 181.674 | 0,15% | Aktien |
| VANGUARD GROUP INC | $6.067.297 | 172.956 | 0,15% | Aktien |
| Decheng Capital LLC | $5.994.700 | 176.887 | 0,15% | Aktien |
| VICTORY CAPITAL MANAGEMENT INC | $5.851.549 | 172.663 | 0,15% | Aktien |
| PEREGRINE CAPITAL MANAGEMENT LLC | $5.743.948 | 169.488 | 0,14% | Aktien |
| Point72 Asset Management, L.P. | $5.724.055 | 168.901 | 0,14% | Aktien |
| AXA Investment Managers S.A. | $5.596.480 | 196.782 | 0,14% | Aktien |
| Mizuho Markets Cayman LP | $5.101.767 | 150.539 | 0,13% | Aktien |
| TD Asset Management Inc | $5.029.276 | 148.400 | 0,12% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5.015.720 | 148.000 | 0,12% | Kaufoption |
| XTX Topco Ltd | $4.914.321 | 145.008 | 0,12% | Aktien |
| Jump Financial, LLC | $4.897.512 | 144.512 | 0,12% | Aktien |
| DCF Advisers, LLC | $4.778.490 | 141.000 | 0,12% | Aktien |
| KORNITZER CAPITAL MANAGEMENT INC /KS | $4.742.329 | 139.933 | 0,12% | Aktien |
| Cutter Capital Management, LP | $4.526.981 | 221.152 | 0,11% | Aktien |
| Jefferies Financial Group Inc. | $4.159.252 | 122.728 | 0,10% | Aktien |
| BOOTHBAY FUND MANAGEMENT, LLC | $4.107.468 | 121.200 | 0,10% | Verkaufsoption |
| Swiss National Bank | $4.104.079 | 121.100 | 0,10% | Aktien |
| D. E. Shaw & Co., Inc. | $4.085.812 | 120.561 | 0,10% | Aktien |
| ADAR1 Capital Management, LLC | $4.020.133 | 118.623 | 0,10% | Aktien |
| ALPS ADVISORS INC | $4.003.934 | 118.145 | 0,10% | Aktien |
| STATE STREET CORP | $3.904.636 | 115.215 | 0,10% | Aktien |
| Walleye Capital LLC | $3.789.546 | 111.819 | 0,09% | Aktien |
| GEODE CAPITAL MANAGEMENT, LLC | $3.562.287 | 105.169 | 0,09% | Aktien |
| Swedbank AB | $3.527.949 | 104.100 | 0,09% | Aktien |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $3.261.302 | 96.232 | 0,08% | Aktien |
| NORTHERN TRUST CORP | $3.184.677 | 93.971 | 0,08% | Aktien |
| Caption Management, LLC | $3.124.658 | 92.200 | 0,08% | Verkaufsoption |
| Squarepoint Ops LLC | $3.118.761 | 92.026 | 0,08% | Aktien |
| Moody Aldrich Partners LLC | $3.071.010 | 90.617 | 0,08% | Aktien |
| Schonfeld Strategic Advisors LLC | $3.042.135 | 89.765 | 0,08% | Aktien |
| Bellevue Group AG | $2.948.227 | 86.994 | 0,07% | Aktien |
| ALGERT GLOBAL LLC | $2.756.613 | 81.340 | 0,07% | Aktien |
| Man Group plc | $2.739.396 | 80.832 | 0,07% | Aktien |
| TUDOR INVESTMENT CORP ET AL | $2.692.899 | 79.460 | 0,07% | Aktien |
| Y-Intercept (Hong Kong) Ltd | $2.648.029 | 78.136 | 0,07% | Aktien |
| STEMPOINT CAPITAL LP | $2.629.491 | 77.589 | 0,07% | Aktien |
| Headlands Technologies LLC | $2.451.433 | 72.335 | 0,06% | Aktien |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2.284.796 | 67.418 | 0,06% | Aktien |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $2.145.169 | 63.298 | 0,05% | Aktien |
| FOX RUN MANAGEMENT, L.L.C. | $2.015.675 | 59.477 | 0,05% | Aktien |
| Russell Investments Group, Ltd. | $1.989.578 | 58.707 | 0,05% | Aktien |
| China Universal Asset Management Co., Ltd. | $1.647.223 | 48.605 | 0,04% | Aktien |
| Qube Research & Technologies Ltd | $1.595.880 | 47.090 | 0,04% | Aktien |
| FRED ALGER MANAGEMENT, LLC | $1.528.947 | 45.115 | 0,04% | Aktien |
| Palo Alto Investors LP | $1.503.327 | 44.359 | 0,04% | Aktien |
| Knights of Columbus Asset Advisors LLC | $1.484.382 | 43.800 | 0,04% | Aktien |
| FIRST TRUST ADVISORS LP | $1.460.930 | 43.108 | 0,04% | Aktien |
| VANGUARD ASSET MANAGEMENT, Ltd | $1.437.682 | 42.422 | 0,04% | Aktien |
| Fieldview Capital Management, LLC | $1.418.025 | 41.842 | 0,04% | Aktien |
| SEI INVESTMENTS CO | $1.385.017 | 40.868 | 0,03% | Aktien |
| Legal & General Group Plc | $1.333.336 | 39.343 | 0,03% | Aktien |
| CITADEL ADVISORS LLC | $1.301.376 | 38.400 | 0,03% | Kaufoption |
| Ishara Investments LP | $1.250.541 | 36.900 | 0,03% | Aktien |
| BOOTHBAY FUND MANAGEMENT, LLC | $1.211.771 | 35.756 | 0,03% | Aktien |
| BNP PARIBAS FINANCIAL MARKETS | $1.210.212 | 35.710 | 0,03% | Aktien |
| LMR Partners LLP | $1.155.649 | 34.100 | 0,03% | Kaufoption |
| STATE OF WISCONSIN INVESTMENT BOARD | $1.123.759 | 33.159 | 0,03% | Aktien |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1.118.336 | 32.999 | 0,03% | Aktien |
| STIFEL FINANCIAL CORP | $1.079.432 | 31.851 | 0,03% | Aktien |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $1.062.621 | 31.355 | 0,03% | Aktien |
| Quadrature Capital Ltd | $1.036.797 | 30.593 | 0,03% | Aktien |
| VOYA INVESTMENT MANAGEMENT LLC | $916.725 | 27.050 | 0,02% | Aktien |
| Eleva Capital SAS | $823.329 | 25.721 | 0,02% | Aktien |
| AQR CAPITAL MANAGEMENT LLC | $768.998 | 22.691 | 0,02% | Aktien |
| HighVista Strategies LLC | $708.470 | 20.905 | 0,02% | Aktien |
| GLENMEDE TRUST CO NA | $692.033 | 20.420 | 0,02% | Aktien |
| DNB Asset Management AS | $680.850 | 20.090 | 0,02% | Aktien |
| Engineers Gate Manager LP | $661.838 | 19.529 | 0,02% | Aktien |
| State of New Jersey Common Pension Fund D | $661.465 | 19.518 | 0,02% | Aktien |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $647.265 | 19.099 | 0,02% | Aktien |
| Caption Management, LLC | $633.743 | 18.700 | 0,02% | Kaufoption |
| Point72 Asset Management, L.P. | $620.187 | 18.300 | 0,02% | Kaufoption |
| Point72 Asset Management, L.P. | $620.187 | 18.300 | 0,02% | Verkaufsoption |
| WELLS FARGO & COMPANY/MN | $611.308 | 18.038 | 0,02% | Aktien |
| GOLDMAN SACHS GROUP INC | $576.130 | 17.000 | 0,01% | Kaufoption |
| ARIZONA STATE RETIREMENT SYSTEM | $564.472 | 16.656 | 0,01% | Aktien |
| Vanguard Investments Australia, Ltd. | $534.581 | 15.774 | 0,01% | Aktien |
| ENVESTNET ASSET MANAGEMENT INC | $525.973 | 15.520 | 0,01% | Aktien |
| SBI Okasan Asset Management Co.Ltd. | $504.663 | 14.900 | 0,01% | Aktien |
| AlphaCentric Advisors LLC | $503.877 | 14.868 | 0,01% | Aktien |
| ROYAL BANK OF CANADA | $487.000 | 14.362 | 0,01% | Aktien |
| KLP KAPITALFORVALTNING AS | $464.293 | 13.700 | 0,01% | Aktien |
| KEYBANK NATIONAL ASSOCIATION/OH | $422.947 | 12.480 | 0,01% | Aktien |
| TWO SIGMA INVESTMENTS, LP | $406.714 | 12.001 | 0,01% | Aktien |
| PSP Research LLC | $406.680 | 12.000 | 0,01% | Aktien |
| JANE STREET GROUP, LLC | $406.680 | 12.000 | 0,01% | Kaufoption |
| PTM WEALTH MANAGEMENT, LLC | $382.356 | 12.900 | 0,01% | Aktien |
| Virtus Investment Advisers, LLC | $364.758 | 10.763 | 0,01% | Aktien |
| Financiere des Professionnels - Fonds d'investissement inc. | $364.114 | 10.744 | 0,01% | Aktien |
| Cerity Partners LLC | $340.967 | 10.061 | 0,01% | Aktien |
| Caitong International Asset Management Co., Ltd | $328.123 | 9.682 | 0,01% | Aktien |
| Brevan Howard Capital Management LP | $323.582 | 9.548 | 0,01% | Aktien |
| LETKO, BROSSEAU & ASSOCIATES INC | $321.108 | 9.475 | 0,01% | Aktien |
| BAMCO INC /NY/ | $305.010 | 9.000 | 0,01% | Aktien |
| AdvisorNet Financial, Inc | $283.829 | 8.375 | 0,01% | Aktien |
| Pictet Asset Management Holding SA | $277.051 | 8.175 | 0,01% | Aktien |
| Creative Planning | $275.695 | 8.135 | 0,01% | Aktien |
| BARCLAYS PLC | $273.560 | 8.072 | 0,01% | Aktien |
| CITIGROUP INC | $272.001 | 8.026 | 0,01% | Aktien |
| Mesirow Financial Investment Management, Inc. | $252.989 | 7.465 | 0,01% | Aktien |
| JANE STREET GROUP, LLC | $247.397 | 7.300 | 0,01% | Verkaufsoption |
| PNC Financial Services Group, Inc. | $247.091 | 7.291 | 0,01% | Aktien |
| US BANCORP \DE\ | $246.922 | 7.286 | 0,01% | Aktien |
| Persistent Asset Partners Ltd | $246.855 | 7.284 | 0,01% | Aktien |
| Wealth Management Associates, Inc. | $239.094 | 7.055 | 0,01% | Aktien |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $237.501 | 7.008 | 0,01% | Aktien |
| Centiva Capital, LP | $237.230 | 7.000 | 0,01% | Aktien |
| Invesco Ltd. | $224.250 | 6.617 | 0,01% | Aktien |
| Allianz Asset Management GmbH | $223.674 | 6.600 | 0,01% | Aktien |
| CIBC Private Wealth Group LLC | $217.282 | 7.640 | 0,01% | Aktien |
| GUGGENHEIM CAPITAL LLC | $216.896 | 6.400 | 0,01% | Aktien |
| MARSHALL FINANCIAL GROUP INC /ADV | $213.300 | 7.500 | 0,01% | Aktien |
| Mirae Asset Global Investments Co., Ltd. | $177.177 | 5.228 | 0,00% | Aktien |
| Quarry LP | $153.996 | 4.544 | 0,00% | Aktien |
| Tower Research Capital LLC (TRC) | $152.505 | 4.500 | 0,00% | Aktien |
| Mitsubishi UFJ Trust & Banking Corp | $146.744 | 4.330 | 0,00% | Aktien |
| WELLS FARGO & COMPANY/MN | $128.782 | 3.800 | 0,00% | Verkaufsoption |
| Duquesne Family Office LLC | $104.047 | 3.070.146 | 0,00% | Aktien |
| Quantbot Technologies LP | $91.300 | 2.694 | 0,00% | Aktien |
| Toroso Investments, LLC | $84.192 | 2.400 | 0,00% | Kaufoption |
| GF FUND MANAGEMENT CO. LTD. | $82.488 | 2.434 | 0,00% | Aktien |
| NATIONAL BANK OF CANADA /FI/ | $61.431 | 1.813 | 0,00% | Aktien |
| Federation des caisses Desjardins du Quebec | $60.494 | 1.785 | 0,00% | Aktien |
| Parallel Advisors, LLC | $47.446 | 1.400 | 0,00% | Aktien |
| Bayforest Capital Ltd | $43.278 | 1.277 | 0,00% | Aktien |
| PRICE T ROWE ASSOCIATES INC /MD/ | $39.562 | 1.167.357 | 0,00% | Aktien |
| THURSTON, SPRINGER, MILLER, HERD & TITAK, INC. | $36.160 | 1.067 | 0,00% | Aktien |
| Farther Finance Advisors, LLC | $34.093 | 1.006 | 0,00% | Aktien |
| CWM, LLC | $32.586 | 1.018 | 0,00% | Aktien |
| Cheviot Value Management, LLC | $26.976 | 796 | 0,00% | Aktien |
| NWI MANAGEMENT LP | $23.791 | 702.000 | 0,00% | Aktien |
| SBI Securities Co., Ltd. | $20.842 | 615 | 0,00% | Aktien |
| Handelsbanken Fonder AB | $13.409 | 418.900 | 0,00% | Aktien |
| HRT FINANCIAL LP | $11.856 | 349.843 | 0,00% | Aktien |
| Stone House Investment Management, LLC | $11.014 | 325 | 0,00% | Aktien |
| LORD, ABBETT & CO. LLC | $10.389 | 306.560 | 0,00% | Aktien |
| Global Retirement Partners, LLC | $9.150 | 270 | 0,00% | Aktien |
| FIL Ltd | $7.354 | 217 | 0,00% | Aktien |
| NISA INVESTMENT ADVISORS, LLC | $7.083 | 209 | 0,00% | Aktien |
| Arax Advisory Partners | $6.032 | 178 | 0,00% | Aktien |
| JONES FINANCIAL COMPANIES LLLP | $5.584 | 168 | 0,00% | Aktien |
| Continuum Advisory, LLC | $5.219 | 154 | 0,00% | Aktien |
| OSAIC HOLDINGS, INC. | $4.710 | 139 | 0,00% | Aktien |
| Clearstead Advisors, LLC | $2.576 | 76 | 0,00% | Aktien |
| ORG Partners LLC | $2.104 | 60 | 0,00% | Aktien |
| Essential Partners LLC | $1.796 | 53 | 0,00% | Aktien |
| Lindbrook Capital, LLC | $921 | 45 | 0,00% | Aktien |
| Allworth Financial LP | $848 | 25 | 0,00% | Aktien |
| True Wealth Design, LLC | $712 | 21 | 0,00% | Aktien |
| FIDUCIARY FINANCIAL ADVISORS | $441 | 13 | 0,00% | Aktien |
| EverSource Wealth Advisors, LLC | $373 | 11 | 0,00% | Aktien |
| GAMMA Investing LLC | $305 | 9 | 0,00% | Aktien |
| Sunbelt Securities, Inc. | $256 | 8 | 0,00% | Aktien |
| SG Americas Securities, LLC | $115 | 3.384 | 0,00% | Aktien |
| ROTHSCHILD INVESTMENT LLC | $102 | 3 | 0,00% | Aktien |
| IFP Advisors, Inc | $102 | 3 | 0,00% | Aktien |
| KBC Group NV | $84 | 2.483 | 0,00% | Aktien |
| DUPONT CAPITAL MANAGEMENT CORP | $34 | 1 | 0,00% | Aktien |