ENTX Entera Bio Ltd. - Ordinary Shares
NASDAQ · Biotechnology · View on SEC EDGAR ↗ 10-K/10-Q Aug 7, 2026
$3.07
· of 52w range
· above low
· to high
$0.9152w low
$4.2052w high
Market Cap (MRQ)
$151M
P/E (TTM)
9.0
EPS (TTM)
$0.34
Revenue (TTM)
$0
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52W Range
$1–$4
Analyst Rating
BUY
Price Target
$10
P/E
9.0
ROE
-138.9%
Net Profit Margin
-27235.7%
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ENTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$3.07
Market Cap (MRQ)
$151M
P/E (TTM)
9.0
EPS (TTM)
$0.34
Revenue (TTM)
$0
ROE (TTM)
-138.9%
52W Range
$1–$4
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue$42.0K2018-12-31 → 2025-12-31
EPS$0.252016-12-31 → 2025-12-31
Free Cash Flow$-7M2018-12-31 → 2025-12-31
Net margin-27235.7%2018-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | ENTX | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E (TTM) | 9.05Y avg ≈5.2 | ≈5.2 | · | · | |
| P/S | 3375.45Y avg ≈915.0 | ≈915.0 | · | · | |
| P/B (MRQ) | 20.85Y avg ≈5.2 | ≈5.2 | · | · | |
| Price / FCF (TTM) | -13.85Y avg ≈-7.2 | ≈-7.2 | · | · | |
| Price / Cash Flow (TTM) | -13.95Y avg ≈-7.2 | ≈-7.2 | · | · | |
| Price / Tangible Book | 10.85Y avg ≈4.9 | ≈4.9 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | ENTX | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Gross Margin | 0.00%5Y avg ≈9.9% | ≈9.9% | 64.8% | Weak | |
| Operating Margin | -27450.0%5Y avg ≈-14153.3% | ≈-14153.3% | 7.3% | Weak | |
| EBITDA Margin | -27450.0%5Y avg ≈-14153.3% | ≈-14153.3% | 7.9% | Weak | |
| Pretax Margin | -27235.7%5Y avg ≈-14050.5% | ≈-14050.5% | 0.48% | Weak | |
| Net Profit Margin | -27235.7%5Y avg ≈-14087.2% | ≈-14087.2% | -4.3% | Weak | |
| ROA (TTM) | -87.0%5Y avg ≈-79.6% | ≈-79.6% | -28.9% | Weak | |
| ROE (TTM) | -138.9%5Y avg ≈-103.5% | ≈-103.5% | 26.2% | Weak | |
| ROIC | -88.0%5Y avg ≈-101.2% | ≈-101.2% | -39.8% | Weak |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | ENTX | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 9.05Y avg ≈8.6 | ≈8.6 | 5.3 | Strong liquidity | |
| Quick Ratio | 3.25Y avg ≈7.5 | ≈7.5 | 3.8 | Strong liquidity |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
| Metric | 5Y trend | ENTX | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Revenue YoY | -76.8%5Y avg ≈-32.3% | ≈-32.3% | · | · | |
| Revenue CAGR 3Y | -32.1% | · | · | · | |
| Revenue CAGR 5Y | -35.1% | · | · | · | |
| EPS YoY | 0.00%5Y avg ≈-13.7% | ≈-13.7% | · | · | |
| EPS CAGR 3Y | -17.8% | · | · | · |
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
| Metric | 5Y trend | ENTX | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Asset Turnover | 0.05Y avg ≈0.0 | ≈0.0 | 0.5 | Weak | |
| Receivables Turnover | 0.75Y avg ≈1.0 | ≈1.0 | · | · | |
| Revenue / Employee | ≈$2.1K | · | · | · |
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
17.0%
Next Report
Nov 12, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 7, 2026 | $-0.14 | $-0.08 | -71.6% |
| March 31, 2026 | May 8, 2026 | $-0.07 | $-0.15 | 54.2% |
| Dec. 31, 2025 | $-0.07 | $-0.09 | 23.7% | |
| Sept. 30, 2025 | $-0.07 | $-0.09 | 23.7% | |
| June 30, 2025 | $-0.06 | $-0.11 | 46.5% | |
| March 31, 2025 | $-0.06 | $-0.07 | 16.0% | |
| Dec. 31, 2024 | $-0.06 | $-0.08 | 26.5% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue | $42.0K | $181.0K | $0 | $134.0K | $571.0K | $365.0K | $236.0K | $500.0K | |
| Cost of Revenue | $42.0K | $172.0K | $0 | $101.0K | $373.0K | $300.0K | $210.0K | · | |
| Gross Profit | $0 | $9.0K | $0 | $33.0K | $198.0K | $65.0K | · | · | |
| R&D Expense | $6M | $4M | $5M | $6M | $7M | $6M | $7M | $9M | |
| SG&A Expense | $398.0K | $340.0K | $4M | $7M | $6M | $5M | $4M | $3M | |
| Operating Expenses | $12M | $10M | $9M | $13M | $12M | $11M | · | · | |
| Operating Income | $-12M | $-10M | $-9M | $-13M | $-12M | $-11M | $-11M | $-11M | |
| Other Non-op | $90.0K | $58.0K | $31.0K | $83.0K | $-29.0K | $-28.0K | · | · | |
| Pretax Income | $-11M | $-10M | $-9M | $-13M | $-12M | $-11M | $-11M | $-10M | |
| Income Tax | $0 | $14.0K | $29.0K | $137.0K | $-59.0K | $20.0K | · | · | |
| Net Income | $-11M | $-10M | $-9M | $-13M | $-12M | $-11M | $-11M | $-10M | |
| EPS (Basic) | $0.25 | $0.25 | $0.31 | $0.45 | $0.47 | $0.54 | $0.89 | $1.30 | |
| EPS (Diluted) | $0.25 | $0.25 | $0.31 | $0.45 | $0.47 | $0.55 | $0.89 | $1.31 | |
| Shares (Basic) | 46,191,067 | 37,650,179 | 29,007,794 | 28,808,090 | 26,133,770 | 18,417,093 | 12,146,729 | 7,955,447 | |
| Shares (Diluted) | 46,191,067 | 37,650,179 | 29,007,794 | 28,808,090 | 26,133,770 | 18,563,675 | 12,146,729 | 7,983,402 | |
| EBITDA | $-12M | $-10M | $-9M | $-13M | · | $-11M | $-11M | $-11M |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $7M | $9M | $11M | $12M | $25M | $9M | $15M | $8M | |
| Receivables | $0 | $126.0K | $0 | $246.0K | $183.0K | $255.0K | $278.0K | $725.0K | |
| Prepaid Expense | $415.0K | $29.0K | $238.0K | $294.0K | · | · | · | · | |
| Other Current Assets | $107.0K | $186.0K | $238.0K | $294.0K | $254.0K | $261.0K | · | · | |
| Current Assets | $15M | $9M | $11M | $13M | $25M | $9M | $16M | $12M | |
| PP&E (Net) | $134.0K | $57.0K | $100.0K | $139.0K | $156.0K | $192.0K | $202.0K | $224.0K | |
| Intangibles | · | · | · | · | · | $605.0K | $605.0K | $651.0K | |
| Total Assets | $16M | $9M | $12M | $13M | $26M | $10M | $17M | $13M | |
| Accounts Payable | $448.0K | $132.0K | $83.0K | $17.0K | $166.0K | $164.0K | $1M | $1M | |
| Current Liabilities | $2M | $1M | $1M | $1M | $3M | $2M | $5M | $3M | |
| Capital Leases | $260.0K | $102.0K | $256.0K | $0 | $123.0K | $243.0K | · | · | |
| Other Non-current Liabilities | $393.0K | $0 | · | · | · | · | · | · | |
| Total Liabilities | $3M | $1M | $1M | $1M | $3M | $2M | $5M | $3M | |
| Common Stock | $1.0K | $1.0K | $1.0K | · | · | · | · | · | |
| Retained Earnings | $-125M | $-114M | $-104M | $-95M | $-82M | $-70M | $-63M | $-52M | |
| AOCI | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | · | · | |
| Stockholders' Equity | $13M | $8M | $10M | $12M | $23M | $8M | $14M | $10M | |
| Liabilities + Equity | $16M | $9M | $12M | $13M | $26M | $10M | · | · | |
| Shares Outstanding | 46,178,630 | 38,837,220 | 35,476,341 | 28,809,922 | 28,804,411 | 21,057,922 | · | · |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | · | $225.0K | $238.0K | $54.0K | |
| Stock-based Comp | $3M | $3M | $2M | $2M | $2M | $901.0K | · | · | |
| Deferred Tax | $0 | $14.0K | $29.0K | $174.0K | $-217.0K | $0 | · | · | |
| Other Non-cash | · | · | · | · | · | $-665.0K | $2M | $454.0K | |
| Operating Cash Flow | $-7M | $-7M | $-7M | $-12M | $-9M | $-11M | $-9M | $-10M | |
| CapEx | $107.0K | $3.0K | $17.0K | $47.0K | $17.0K | $53.0K | $40.0K | $68.0K | |
| Investing Cash Flow | $-107.0K | $-3.0K | $-17.0K | $-102.0K | $-17.0K | $-53.0K | $4M | $-4M | |
| Stock Issued | $6M | $4M | $5.0K | $0 | $22M | $3M | · | · | |
| Net Stock Activity | $6M | $4M | $5.0K | $0 | · | · | · | · | |
| Financing Cash Flow | $14M | $4M | $6M | $13.0K | $25M | $4M | $13M | $10M | |
| Net Change in Cash | $6M | $-2M | $-1M | $-13M | $16M | $-7M | · | · | |
| Taxes Paid | · | · | $0 | $165.0K | $2.0K | $89.0K | · | · | |
| Free Cash Flow | $-7M | $-7M | $-7M | $-13M | · | $-10M | $-9M | $-10M |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 0.00% | 5.0% | · | 24.6% | · | · | · | · | |
| Operating Margin | -27450.0% | -5295.6% | · | -9714.2% | · | -3050.1% | -4853.4% | -2172.2% | |
| Net Margin | -27235.7% | -5271.3% | · | -9754.5% | · | -2735.1% | -4574.2% | -2060.8% | |
| Pretax Margin | -27235.7% | -5263.5% | · | -9652.2% | · | -2729.6% | · | · | |
| EBITDA Margin | -27450.0% | -5295.6% | · | -9714.2% | · | -2988.5% | -4752.5% | -2161.4% | |
| ROA | -90.1% | -90.2% | -71.4% | -66.8% | · | -74.0% | -71.9% | -77.4% | |
| ROE | -75.4% | -131.3% | -106.9% | -100.3% | · | -97.7% | -98.0% | 96.1% | |
| ROIC | -88.0% | -118.8% | -85.9% | -111.9% | · | -167.4% | · | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 6.9 | 7.6 | 10.3 | 9.6 | · | 2.8 | 3.4 | 7.0 | |
| Quick Ratio | 3.2 | 7.5 | 10.1 | 9.4 | · | 2.7 | 3.4 | 4.6 |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | |
| Receivables Turnover | 0.7 | 2.9 | 0.0 | 0.6 | · | 1.4 | 0.5 | 1.4 |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $0.28 | $0.21 | $0.29 | $0.41 | · | · | · | · | |
| Revenue / Share | $0.00 | $0.00 | $0.00 | $0.00 | · | $0.02 | $0.02 | $0.06 | |
| Cash Flow / Share | $-0.16 | $-0.18 | $-0.25 | $-0.43 | · | $-0.56 | $-0.73 | $-1.23 | |
| Cash / Share | $0.15 | $0.22 | $0.31 | $0.43 | · | · | · | · | |
| EPS (TTM) | $0.25 | $0.25 | $0.31 | $0.45 | $0.47 | $0.55 | $0.89 | $1.31 |
Growth Rates
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -76.8% | · | · | -76.5% | 56.4% | · | · | · | |
| Revenue CAGR 3Y | -32.1% | -31.8% | · | · | · | · | · | · | |
| Revenue CAGR 5Y | -35.1% | · | · | · | · | · | · | · | |
| EPS YoY | 0.00% | -19.4% | -31.1% | -4.3% | · | · | · | · | |
| EPS CAGR 3Y | -17.8% | -19.0% | · | · | · | · | · | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $42.0K | $181.0K | $0 | $134.0K | $571.0K | $365.0K | $236.0K | $500.0K | |
| Net Income TTM | $-11M | $-10M | $-9M | $-13M | $-12M | $-11M | $-11M | $-10M | |
| Market Cap | $90M | $82M | $21M | $21M | · | · | · | · | |
| P/E | 7.8 | 8.5 | 1.9 | 1.6 | 6.0 | 2.0 | 2.4 | 2.3 | |
| P/S | 2133.0 | 454.9 | · | 156.9 | · | · | · | · | |
| P/B | 6.8 | 10.2 | 2.0 | 1.8 | · | · | · | · | |
| P / Tangible Book | 6.8 | 10.2 | 2.0 | 1.8 | 3.6 | · | · | · | |
| P / Cash Flow | -12.2 | -12.1 | -2.9 | -1.7 | · | · | · | · | |
| P / FCF | -12.0 | -12.1 | -2.9 | -1.7 | · | · | · | · | |
| Earnings Yield | 12.9% | 11.8% | 51.7% | 61.6% | 16.7% | 50.9% | 41.6% | 43.0% |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 | $42.0K | $82.0K | $42.0K | $57.0K | $0 | $0 | $0 | $0 | $0 | $14.0K | $8.0K | |
| Cost of Revenue | $0 | $0 | $0 | $0 | $0 | $42.0K | $82.0K | $42.0K | $48.0K | $0 | $0 | $0 | $0 | $0 | $8.0K | $6.0K | |
| Gross Profit | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $9.0K | · | $0 | $0 | $0 | $0 | $6.0K | $2.0K | |
| R&D Expense | $3M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $735.0K | $1M | $1M | $1M | $931.0K | $1M | $1M | |
| SG&A Expense | $124.0K | $128.0K | $-1M | $122.0K | $103.0K | $123.0K | $-1M | $62.0K | $134.0K | $1M | $973.0K | $1M | $1M | $1M | $2M | $1M | |
| Operating Expenses | $5M | $4M | $3M | $3M | $3M | $3M | $2M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $3M | $3M | |
| Operating Income | $-5M | $-4M | $-3M | $-3M | $-3M | $-3M | $-2M | $-3M | $-2M | $-2M | $-2M | $-2M | $-2M | $-2M | $-3M | $-3M | |
| Other Non-op | $-3M | $34.0K | $26.0K | $56.0K | $12.0K | $-4.0K | $-7.0K | $0 | $20.0K | $45.0K | $-32.0K | $36.0K | $5.0K | $22.0K | $-13.0K | $-8.0K | |
| Pretax Income | · | · | · | · | · | · | $-2M | $-3M | · | · | $-2M | $-2M | $-2M | $-2M | $-3M | $-3M | |
| Income Tax | · | · | · | · | · | · | $14.0K | $0 | · | · | $0 | $29.0K | $0 | $0 | $-46.0K | $194.0K | |
| Net Income | $-7M | $-4M | $-3M | $-3M | $-3M | $-3M | $-2M | $-3M | $-2M | $-2M | $-2M | $-2M | $-2M | $-2M | $-3M | $-3M | |
| EPS (Basic) | $0.14 | $0.07 | $0.06 | $0.07 | $0.06 | $0.06 | $0.06 | $0.08 | $0.06 | $0.05 | $0.07 | $0.08 | $0.08 | $0.08 | $0.10 | $0.11 | |
| EPS (Diluted) | $0.14 | $0.07 | $0.06 | $0.07 | $0.06 | $0.06 | $0.06 | $0.08 | $0.06 | $0.05 | $0.07 | $0.08 | $0.08 | $0.08 | $0.10 | $0.11 | |
| Shares (Basic) | 50,451,232 | 47,756,409 | · | 47,089,814 | 46,836,700 | 43,377,391 | · | 37,644,612 | 37,090,160 | 36,735,429 | · | 28,813,952 | 28,812,375 | 28,809,922 | · | 28,809,922 | |
| Shares (Diluted) | 50,451,232 | 47,756,409 | · | 47,089,814 | 46,836,700 | 43,377,391 | · | 37,644,612 | 37,090,160 | 36,735,429 | · | 28,813,952 | 28,812,375 | 28,809,922 | · | 28,809,922 | |
| EBITDA | $-5M | $-4M | · | $-3M | $-3M | $-3M | · | $-3M | $-2M | $-2M | · | $-2M | $-2M | $-2M | · | $-3M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $11M | $4M | $7M | $9M | $11M | $13M | $9M | $7M | $9M | $9M | $11M | $8M | $9M | $11M | $12M | $14M | |
| Receivables | · | · | $0 | $0 | $0 | $126.0K | $126.0K | $42.0K | $57.0K | · | $0 | $0 | $29.0K | $29.0K | $246.0K | $233.0K | |
| Prepaid Expense | $465.0K | $566.0K | $37.0K | $405.0K | $438.0K | $519.0K | $29.0K | $383.0K | $482.0K | $562.0K | · | $431.0K | $650.0K | · | · | · | |
| Other Current Assets | $144.0K | $256.0K | $415.0K | $262.0K | $192.0K | $165.0K | $186.0K | $89.0K | $67.0K | $39.0K | $238.0K | $263.0K | $354.0K | $653.0K | $294.0K | $634.0K | |
| Current Assets | $19M | $12M | $15M | $17M | $19M | $21M | $9M | $7M | $10M | $10M | $11M | $8M | $10M | $11M | $13M | $15M | |
| PP&E (Net) | $121.0K | $127.0K | $134.0K | $114.0K | $79.0K | $57.0K | $57.0K | $65.0K | $76.0K | $87.0K | $100.0K | $108.0K | $122.0K | $136.0K | $139.0K | $152.0K | |
| Total Assets | $19M | $13M | $16M | $17M | $20M | $22M | $9M | $8M | $10M | $10M | $12M | $9M | $10M | $12M | $13M | $16M | |
| Accounts Payable | $575.0K | $274.0K | $448.0K | $216.0K | $383.0K | $134.0K | $132.0K | $184.0K | $69.0K | $66.0K | $83.0K | $564.0K | $240.0K | $150.0K | $17.0K | $413.0K | |
| Current Liabilities | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $1M | $1M | $1M | |
| Capital Leases | $226.0K | $263.0K | $260.0K | $41.0K | $9.0K | $51.0K | $102.0K | $147.0K | $179.0K | $224.0K | $256.0K | $271.0K | $316.0K | · | $0 | $3.0K | |
| Other Non-current Liabilities | · | · | $393.0K | · | · | · | $0 | · | · | · | · | · | · | · | · | · | |
| Total Liabilities | $12M | $2M | $3M | $2M | $2M | $2M | $1M | $1M | $2M | $1M | $1M | $2M | $2M | $2M | $1M | $1M | |
| Common Stock | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | $1.0K | · | · | · | · | · | |
| Retained Earnings | $-136M | $-129M | $-125M | $-122M | $-119M | $-116M | $-114M | $-112M | $-109M | $-106M | $-104M | $-102M | $-100M | $-98M | $-95M | $-92M | |
| AOCI | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | $41.0K | |
| Stockholders' Equity | $7M | $11M | $13M | $15M | $17M | $19M | $8M | $6M | $9M | $9M | $10M | $6M | $8M | $10M | $12M | $14M | |
| Liabilities + Equity | $19M | $13M | $16M | $17M | $20M | $22M | $9M | $8M | $10M | $10M | $12M | $9M | $10M | $12M | $13M | $16M | |
| Shares Outstanding | 49,290,233 | 46,622,239 | 46,178,630 | 45,664,506 | 45,452,167 | 45,420,677 | 38,837,220 | 36,512,214 | 36,314,579 | 35,526,281 | 35,476,341 | 28,813,952 | 28,813,952 | 28,809,922 | 28,809,922 | 28,809,922 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $624.0K | $672.0K | $710.0K | $927.0K | $509.0K | $604.0K | $566.0K | $928.0K | $598.0K | $464.0K | $318.0K | $383.0K | $472.0K | $516.0K | $477.0K | $110.0K | |
| Deferred Tax | · | · | · | · | · | · | $14.0K | · | · | · | $0 | $29.0K | $0 | $0 | $23.0K | $214.0K | |
| Operating Cash Flow | $-3M | $-3M | $-2M | $-3M | $-2M | $-1M | $-1M | $-2M | $-1M | $-2M | $-3M | $-2M | $-2M | $-2M | $-2M | $-3M | |
| CapEx | $3.0K | $0 | $27.0K | $43.0K | $29.0K | $8.0K | $3.0K | $0 | $0 | $0 | $5.0K | $0 | $1.0K | $11.0K | $3.0K | $2.0K | |
| Investing Cash Flow | $-3.0K | $0 | $-27.0K | $-43.0K | $-29.0K | $-8.0K | $-3.0K | $0 | $0 | $0 | $-5.0K | $0 | $-1.0K | $-11.0K | $-3.0K | $-57.0K | |
| Stock Issued | $0 | $0 | $0 | $71.0K | $0 | $6M | $3M | $19.0K | $620.0K | $0 | $0 | $0 | · | · | $0 | $0 | |
| Net Stock Activity | · | $0 | · | · | · | $6M | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $10M | $130.0K | $174.0K | $250.0K | $-51.0K | $13M | $3M | $13.0K | $1M | $30.0K | $6M | $0 | $5.0K | $0 | $0 | $0 | |
| Net Change in Cash | · | · | · | · | $-2M | $12M | $2M | $-2M | $-119.0K | $-2M | $3M | $-2M | $-2M | $-2M | $-2M | $-3M | |
| Taxes Paid | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | · | |
| Free Cash Flow | · | $-3M | · | · | · | $-1M | · | · | · | $-2M | · | · | · | $-2M | · | · |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | · | · | · | · | · | 0.00% | · | 0.00% | 15.8% | · | · | · | · | · | · | 25.0% | |
| Operating Margin | · | · | · | · | · | -6102.4% | · | -7192.9% | -3798.2% | · | · | · | · | · | · | -35812.5% | |
| Net Margin | · | · | · | · | · | -6111.9% | · | -7192.9% | -3763.2% | · | · | · | · | · | · | -38337.5% | |
| Pretax Margin | · | · | · | · | · | · | · | -7192.9% | · | · | · | · | · | · | · | -35912.5% | |
| EBITDA Margin | · | · | · | · | · | -6102.4% | · | -7192.9% | -3798.2% | · | · | · | · | · | · | -35812.5% | |
| ROA | -37.4% | -20.2% | · | -25.4% | -17.9% | -16.1% | · | -37.0% | -20.9% | -18.5% | · | -19.7% | -15.8% | -12.9% | · | -39.5% | |
| ROE | -59.6% | -23.3% | · | -29.5% | -20.6% | -18.2% | · | -47.6% | -25.6% | -21.3% | · | -23.2% | -18.2% | -14.7% | · | -42.9% | |
| ROIC | · | · | · | · | · | · | · | -46.8% | · | · | · | -38.7% | -28.3% | -21.9% | · | -21.4% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 9.0 | 7.9 | · | 10.8 | 10.5 | 13.1 | · | 6.6 | 7.4 | 8.7 | · | 4.0 | 5.3 | 7.6 | · | 12.7 | |
| Quick Ratio | 5.4 | 2.6 | · | 5.5 | 5.9 | 7.8 | · | 6.3 | 7.0 | 8.2 | · | 3.7 | 4.9 | 7.2 | · | 12.2 |
Efficiency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | |
| Receivables Turnover | · | · | · | 0.0 | 0.0 | 0.5 | · | 2.0 | 1.3 | · | · | 0.0 | 0.0 | 0.0 | · | 0.1 |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $0.15 | $0.23 | · | $0.33 | $0.38 | $0.43 | · | $0.18 | $0.23 | $0.25 | · | $0.22 | $0.29 | $0.35 | · | $0.50 | |
| Revenue / Share | $0.00 | $0.00 | · | $0.00 | $0.00 | $0.00 | · | $0.00 | $0.00 | · | · | $0.00 | $0.00 | $0.00 | · | $0.00 | |
| Cash Flow / Share | · | $-0.06 | · | · | · | $-0.03 | · | · | · | $-0.05 | · | · | · | $-0.06 | · | · | |
| Cash / Share | $0.23 | $0.09 | · | $0.19 | $0.24 | $0.28 | · | $0.19 | $0.25 | $0.26 | · | $0.26 | $0.32 | $0.37 | · | $0.50 | |
| EPS (TTM) | $0.34 | $0.26 | · | $0.25 | $0.26 | $0.26 | · | $0.26 | $0.26 | $0.28 | · | $0.34 | $0.37 | $0.40 | · | $0.50 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $0 | · | $124.0K | $166.0K | $223.0K | · | $99.0K | $57.0K | $0 | · | $14.0K | $22.0K | $66.0K | · | $285.0K | |
| Net Income TTM | $-17M | $-12M | · | $-11M | $-11M | $-10M | · | $-9M | $-9M | $-9M | · | $-10M | $-11M | $-11M | · | $-14M | |
| Market Cap | $87M | $52M | · | $88M | $86M | $77M | · | $69M | $67M | $59M | · | $21M | $24M | $33M | · | $30M | |
| P/E | 5.2 | 4.3 | · | 7.7 | 7.3 | 6.5 | · | 7.3 | 7.1 | 6.0 | · | 2.1 | 2.3 | 2.9 | · | 2.1 | |
| P/S | · | · | · | 707.1 | 520.2 | 346.3 | · | 700.7 | 1172.3 | · | · | 1492.2 | 1104.1 | 506.4 | · | 105.1 | |
| P/B | 12.0 | 4.8 | · | 5.8 | 5.0 | 4.0 | · | 10.8 | 7.8 | 6.7 | · | 3.3 | 3.0 | 3.3 | · | 2.1 | |
| P / Tangible Book | 12.0 | 4.8 | · | 5.8 | 5.0 | 4.0 | · | 10.8 | 7.8 | 6.7 | · | 3.3 | 3.0 | 3.3 | · | 2.1 | |
| P / Cash Flow | · | -16.7 | · | · | · | -55.0 | · | · | · | -31.9 | · | · | · | -20.8 | · | · | |
| Earnings Yield | 19.2% | 23.4% | · | 13.0% | 13.7% | 15.3% | · | 13.7% | 14.1% | 16.8% | · | 46.9% | 43.9% | 34.5% | · | 48.1% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Revenue | $42.0K | $181.0K | $0 | $134.0K | $571.0K |
| Gross Margin % | 0.00% | 5.0% | · | 24.6% | · |
| Operating Margin % | -27450.0% | -5295.6% | · | -9714.2% | · |
| Net Income | $-11M | $-10M | $-9M | $-13M | $-12M |
| Diluted EPS | $0.25 | $0.25 | $0.31 | $0.45 | $0.47 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 6.9 | 7.6 | 10.3 | 9.6 | · |
| Quick Ratio | 3.2 | 7.5 | 10.1 | 9.4 | · |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Free Cash Flow | $-7M | $-7M | $-7M | $-13M | · |
Institutional owners (13F) 30 filers · $18.8M total · As of Sept. 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
30
Value held
$18.8M
New positions
8
Exited positions
6
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 8 (0 vs prior Q) | 6 (+2 vs prior Q) | 8 (+3 vs prior Q) | 6 (-1 vs prior Q) | +2.9M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Knoll Capital Management, LLC | $10,410,925 | 5,881,879 | 55.23% | Shares |
| BVF INC/IL | $4,292,250 | 2,425,000 | 22.77% | Shares |
| Siren, L.L.C. | $1,303,529 | 736,457 | 6.92% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $652,859 | 368,847 | 3.46% | Shares |
| Parkman Healthcare Partners LLC | $485,860 | 274,497 | 2.58% | Shares |
| PNC Financial Services Group, Inc. | $483,265 | 273,031 | 2.56% | Shares |
| Seven Fleet Capital Management LP | $338,697 | 191,354 | 1.80% | Shares |
| SIGNATURE ESTATE & INVESTMENT ADVISORS LLC | $137,724 | 47,328 | 0.73% | Shares |
| HighTower Advisors, LLC | $132,935 | 74,573 | 0.71% | Shares |
| Schonfeld Strategic Advisors LLC | $104,201 | 58,871 | 0.55% | Shares |
| TWO SIGMA SECURITIES, LLC | $86,010 | 48,593 | 0.46% | Shares |
| CITADEL ADVISORS LLC | $68,683 | 38,804 | 0.36% | Shares |
| JPMORGAN CHASE & CO | $67,457 | 40,883 | 0.36% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $52,937 | 29,908 | 0.28% | Shares |
| DIADEMA PARTNERS LP | $41,170 | 23,260 | 0.22% | Shares |
| XTX Topco Ltd | $36,389 | 20,559 | 0.19% | Shares |
| Gem Investment Advisors, LLC | $33,869 | 19,135 | 0.18% | Shares |
| JANE STREET GROUP, LLC | $30,676 | 17,331 | 0.16% | Shares |
| SIMPLEX TRADING, LLC | $27,785 | 15,698 | 0.15% | Shares |
| UBS Group AG | $22,520 | 12,723 | 0.12% | Shares |
| CITADEL ADVISORS LLC | $17,877 | 10,100 | 0.09% | Put option |
| Persistent Asset Partners Ltd | $10,409 | 5,881 | 0.06% | Shares |
| Cubist Systematic Strategies, LLC | $8,972 | 4,673 | 0.05% | Shares |
| MORGAN STANLEY | $885 | 500 | 0.00% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $708 | 400 | 0.00% | Shares |
| HRT FINANCIAL LP | $128 | 72,486 | 0.00% | Shares |
| GROUP ONE TRADING LLC | $90 | 51 | 0.00% | Shares |
| Virtu Financial LLC | $65 | 36,921 | 0.00% | Shares |
| SG Americas Securities, LLC | $25 | 13,913 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $3 | 1 | 0.00% | Shares |
Activists & 5%+ owners 1 position
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| BIOTECHNOLOGY VALUE FUND L P, BVF I GP LLC, BIOTECHNOLOGY VALUE FUND II LP, BVF II GP LLC, Biotechnology Value Trading Fund OS LP, BVF Partners OS Ltd., BVF GP HOLDINGS LLC, BVF PARTNERS L P/IL, BVF INC/IL, LAMPERT MARK N | Aug. 4, 2026 | 9.99% | Initial filing | Board campaign | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 17 insiders · 4 officers · 5 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Spiros Jamas | Chief Executive Officer | Jan. 18, 2022 P | 10,000 | 0 | 0 | $0 |
| Ramesh Ratan | U.S.based CFO | Jan. 19, 2022 P | 10,000 | 0 | 0 | $0 |
| Phillip Schwartz | President of R&D | Jan. 20, 2022 P | 607,410 | 0 | 0 | $0 |
| Arthur C Santora II | Chief Medical Officer | April 24, 2023 A | · | 0 | 0 | $0 |
| Gerald M Ostrov | Director | Jan. 1, 2026 A | 75,657 | 0 | 0 | $0 |
| Gerald M Lieberman | Director | Jan. 1, 2026 A | 338,454 | 0 | 0 | $0 |
| Ron Mayron | Director | Jan. 1, 2024 A | 7,000 | 0 | 0 | $0 |
| Roger Garceau | Director | Jan. 1, 2024 A | · | 0 | 0 | $0 |
| Gregory Burshtein | · | Aug. 7, 2026 A | 189,033 | 0 | 0 | $0 |
| Haya Taitel | · | Aug. 7, 2026 A | 119,269 | 1 | 0 | $11,100 |
| Dana Yaacov-Garbeli | · | Aug. 7, 2026 A | 171,441 | 0 | 0 | $0 |
| Yonatan Malca | · | Aug. 7, 2026 A | 100,231 | 0 | 0 | $0 |
| Sean Ellis | · | Aug. 7, 2026 A | 208,132 | 2 | 0 | $34,620 |
| Hillel Galitzer | · | Aug. 7, 2026 A | 163,566 | 0 | 0 | $0 |
| Miranda Jayne Toledano | · | Aug. 7, 2026 A | 847,135 | 1 | 0 | $19,910 |
| Geno J Germano | · | Aug. 7, 2026 A | 65,014 | 2 | 0 | $55,800 |
| Steven D Rubin | · | Aug. 7, 2026 A | 34,117 | 2 | 0 | $19,450 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ENTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 11 analysts
BUY
Median target
$9.50
+209.4%
4 36.4%
Strong Buy
6 54.5%
Buy
1 9.1%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
4 analysts · 2026-10-24Mean target $9.75 +217.6%
← Below all targets
Current price $3.07
Low$9.00
Mean$9.75
High$11.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
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Source: SEC 10-Q filed Aug 7, 2026