MCRB Seres Therapeutics, Inc. - Common Stock
$4.59
Price · Aug 19, 2026
Fundamentals as of Aug 5, 2026
52W Range
$4–$30
1% of range
Analyst Rating
BUY
8 analysts
Price Target
$17
+270% upside
P/E (TTM)
7.2
ROE
14.8%
Net Profit Margin
721.9%
MCRB Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$4.59
Market Cap
$44M
P/E (TTM)
7.2
EPS (TTM)
$0.64
Revenue (TTM)
$789.0K
Div Yield
—
ROE
14.8%
Debt/Equity
—
52W Range
$4 – $30
MCRB Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$789.0K
2016-12-31
→
2025-12-31
EPS
$0.64
2020-12-31
→
2025-12-31
Free Cash Flow
$865.0K
2016-12-31
→
2025-12-31
Margins
721.9%
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
MCRB
Peer Median
P/E (TTM)
7.2
0.8
P/S (TTM)
55.8
6.2
P/B
1.0
3.0
Price / FCF
50.9
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
MCRB
Peer Median
Operating Margin
-11910.1%
—
Net Profit Margin
721.9%
-1056.6%
ROA
4.1%
-118.6%
ROE
14.8%
-139.5%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
MCRB
Peer Median
Current Ratio
2.6
2.1
Quick Ratio
2.4
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
MCRB
Peer Median
Revenue CAGR 3Y
-52.0%
—
Revenue CAGR 5Y
-52.7%
—
Net Income YoY
4088.2%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
MCRB
Peer Median
MCRB Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
8 analysts
- Strong Buy 2 25.0%
- Buy 5 62.5%
- Hold 1 12.5%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
2 analysts · 2026-08-15
Median
$17.00
← Below all targets
$4.59
Low
$12.00
High
$22.00
Median target
$17.00
+270.4%
Mean target
$17.00
+270.4%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-0.26%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| June 30, 2026 | $-1.50 | $-2.23 | 0.73% |
| March 31, 2026 | $-2.08 | $-1.92 | -0.16% |
| Dec. 31, 2025 | $-1.78 | $-2.15 | 0.37% |
| Sept. 30, 2025 | $0.94 | $1.31 | -0.37% |
| June 30, 2025 | $-2.27 | $-2.54 | 0.27% |
| March 31, 2025 | $-2.96 | $-0.55 | -2.4% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| MCRB | $142M | 23.2 | — | 721.9% | 14.8% | — |
| MGX | $61M | -0.7 | -51.8% | -348.5% | -49.6% | — |
| KPTI | $135M | -0.4 | 0.57% | -134.2% | 73.7% | — |
| TVGN | — | — | — | — | — | — |
| ELUT | — | 0.8 | -15.0% | 434.2% | -753.4% | 53.7% |
| ALGS | $58M | -3.8 | -39.5% | -1106.7% | -31.1% | — |
| CRVO | $73M | — | -58.9% | -673.1% | -104.4% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $789.0K | $0 | $0 | $7M | $145M | $33M | $35M | $28M | $32M | $22M | $0 | |
| R&D Expense | $49M | $65M | $118M | $110M | $142M | $91M | $80M | $96M | $89M | $82M | $38M | |
| SG&A Expense | $39M | $53M | $78M | $70M | $69M | $31M | $25M | $33M | $34M | $33M | $17M | |
| Operating Expenses | $95M | $121M | $195M | $180M | $209M | $121M | $106M | $129M | $123M | $115M | $55M | |
| Operating Income | $-94M | $-121M | $-195M | $-180M | $-64M | $-88M | $-72M | $-100M | $-91M | $-93M | $-55M | |
| Interest Income | $2M | $4M | $7M | $3M | $3M | $946.0K | $1M | $1M | $2M | · | · | |
| Other Non-op | $17M | $-14M | $134.0K | $-705.0K | $-1M | $981.0K | $1M | $1M | $2M | $1M | $76.0K | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $6M | $136.0K | $-114M | $-250M | $-66M | $-89M | $-70M | $-99M | $-89M | $-92M | $-55M | |
| EPS (Basic) | $0.64 | $0.00 | $-17.77 | $-2.31 | $-0.72 | $-1.12 | · | · | · | · | · | |
| EPS (Diluted) | $0.64 | $0.00 | $-17.77 | $-2.31 | $-0.72 | $-1.12 | · | · | · | · | · | |
| Shares (Basic) | 8,858,975 | 7,769,910 | 6,400,339 | 108,077,043 | 91,702,866 | 79,789,220 | · | · | · | · | · | |
| Shares (Diluted) | 8,869,742 | 7,769,910 | 6,400,339 | 108,077,043 | 91,702,866 | 79,789,220 | · | · | · | · | · | |
| EBITDA | $-90M | $-116M | $-102M | $-240M | $-59M | $-82M | $-64M | $-92M | $-84M | $-89M | $-54M |
Balance Sheet 25
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $46M | $31M | $128M | $163M | $180M | $116M | $65M | $86M | $36M | $55M | $74M | |
| Short-term Investments | · | · | $0 | $18M | $111M | $138M | $30M | · | $114M | $139M | $131M | |
| Receivables | $157.0K | $0 | · | · | · | $9M | $2M | · | · | · | · | |
| Inventory | · | · | $30M | $0 | · | · | · | · | · | · | · | |
| Prepaid Expense | $3M | $6M | $8M | $13M | $13M | $6M | $4M | $7M | $5M | $5M | $3M | |
| Current Assets | $49M | $39M | $175M | $195M | $304M | $269M | $100M | $93M | $155M | $198M | $208M | |
| PP&E (Net) | $8M | $12M | $18M | $23M | $18M | $14M | $19M | $26M | $33M | $36M | $8M | |
| PP&E (Gross) | $64M | $65M | $67M | $68M | $58M | $48M | $47M | $47M | $45M | $41M | $9M | |
| Accum. Depreciation | $57M | $53M | $49M | $45M | $40M | $34M | $28M | $20M | $12M | $5M | $1M | |
| Other Non-current Assets | $31.0K | $31.0K | $2M | $10M | $5M | · | · | · | · | · | · | |
| Total Assets | $138M | $140M | $359M | $349M | $355M | $343M | $132M | $120M | $190M | $273M | $217M | |
| Accounts Payable | $2M | $4M | $4M | $17M | $14M | $4M | $5M | $6M | $7M | $8M | $5M | |
| Short-term Debt | · | · | $0 | $456.0K | $0 | $454.0K | · | · | · | · | · | |
| Current Liabilities | $19M | $41M | $99M | $86M | $82M | $46M | $46M | $42M | $32M | $30M | $11M | |
| Capital Leases | $73M | $83M | $92M | $108M | $18M | $11M | $16M | · | · | · | · | |
| Other Non-current Liabilities | $2M | $2M | $2M | $1M | $11M | $1M | $502.0K | $644.0K | $1M | · | · | |
| Total Liabilities | $94M | $126M | $403M | $338M | $223M | $168M | $181M | $169M | $129M | $140M | $12M | |
| Long-term Debt | · | · | $110M | $50M | $24M | $25M | $25M | · | · | · | · | |
| Total Debt | · | · | $0 | $456.0K | · | $454.0K | · | · | · | · | · | |
| Common Stock | $10.0K | $9.0K | $135.0K | $125.0K | $92.0K | $91.0K | $70.0K | $41.0K | $40.0K | $40.0K | $39.0K | |
| Retained Earnings | $-972M | $-978M | $-978M | $-865M | $-614M | $-549M | $-460M | $-389M | $-264M | $-174M | $-83M | |
| AOCI | · | $0 | $0 | $-12.0K | $-60.0K | $-47.0K | · | · | $-146.0K | $-149.0K | $30.0K | |
| Stockholders' Equity | $44M | $14M | $-45M | $11M | $132M | $175M | $-48M | $-48M | $61M | $133M | $205M | |
| Liabilities + Equity | $138M | $140M | $359M | $349M | $355M | $343M | $132M | $120M | $190M | $273M | $217M | |
| Shares Outstanding | 9,556,466 | 8,650,227 | 6,752,073 | 6,261,400 | 91,889,418 | 91,459,239 | 70,143,252 | 40,936,735 | 40,571,015 | 40,355,753 | 39,082,017 |
Cash Flow 16
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $4M | $5M | $6M | $7M | $6M | $7M | $8M | $8M | $7M | $4M | $728.0K | |
| Stock-based Comp | $11M | $21M | $34M | $25M | $20M | $9M | $8M | $17M | $17M | $17M | $10M | |
| Restructuring | $1M | · | $6M | · | $0 | $0 | $1M | $0 | $0 | · | · | |
| Other Non-cash | $-20M | $-175M | $-44M | $-11M | $46M | $-20M | $-22M | $12M | $-11M | $114M | $4M | |
| Operating Cash Flow | $1M | $-149M | $-117M | $-229M | $7M | $-94M | $-77M | $-63M | $-76M | $44M | $-41M | |
| CapEx | $252.0K | $380.0K | $8M | $10M | $10M | $591.0K | $1M | $2M | $5M | $21M | $4M | |
| Investing Cash Flow | $-42.0K | $142M | $11M | $82M | $64M | $-159M | $-31M | $112M | $56M | $-66M | · | |
| Debt Issued | · | · | · | $28M | $0 | $0 | $25M | · | · | · | · | |
| Net Debt Issued | · | · | · | $28M | · | · | $25M | · | · | · | · | |
| Stock Issued | · | $0 | $0 | $97M | $0 | $244M | $61M | · | · | · | $143M | |
| Stock Repurchased | · | · | · | · | · | · | · | · | $33.0K | · | · | |
| Net Stock Activity | · | $0 | $0 | $97M | · | $244M | $61M | · | $-33.0K | · | $143M | |
| Financing Cash Flow | $14M | $-90M | $72M | $130M | $1M | $303M | $86M | $268.0K | $83.0K | $2M | · | |
| Net Change in Cash | · | · | · | · | · | $51M | $-21M | $50M | $-20M | $-20M | $-40M | |
| Taxes Paid | $0 | · | · | · | · | · | · | · | · | · | · | |
| Free Cash Flow | $865.0K | $-149M | $-125M | $-239M | $-3M | $-94M | $-78M | $-65M | $-80M | $22M | $-45M |
Profitability 5
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -11910.1% | · | -85.5% | -3458.1% | -44.5% | -265.3% | -208.3% | -354.8% | -284.7% | -426.5% | · | |
| Net Margin | 721.9% | · | -90.0% | -3509.5% | -45.2% | -268.3% | -203.7% | -350.0% | -278.4% | -420.7% | · | |
| EBITDA Margin | -11386.3% | · | -80.5% | -3365.1% | -40.4% | -245.5% | -186.3% | -327.0% | -262.1% | -407.2% | · | |
| ROA | 4.1% | 0.05% | -32.1% | -71.1% | -18.8% | -37.5% | -55.6% | -63.8% | -38.7% | -37.4% | -32.8% | |
| ROE | 14.8% | 0.72% | 379.2% | -638.4% | -42.7% | -49.1% | 174.5% | 251.7% | -92.5% | -54.2% | -61.3% |
Liquidity & Solvency 3
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.6 | 0.9 | 1.8 | 2.3 | 3.7 | 5.8 | 2.2 | 2.2 | 4.9 | 6.5 | 19.0 | |
| Quick Ratio | 2.4 | 0.7 | 1.3 | 2.1 | 3.5 | 5.7 | 1.5 | 2.0 | 4.7 | 6.3 | 18.8 | |
| Debt / Equity | · | · | 0.0 | 0.0 | · | 0.0 | · | · | · | · | · |
Efficiency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | 0.4 | 0.0 | 0.4 | 0.1 | 0.3 | 0.2 | 0.1 | 0.1 | 0.0 | |
| Receivables Turnover | 10.1 | · | · | · | · | 5.9 | 38.7 | · | · | · | · |
Growth Rates 4
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | · | · | · | -95.1% | 336.3% | · | · | · | · | · | · | |
| Revenue CAGR 3Y | -52.0% | · | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | -52.7% | · | · | · | · | · | · | · | · | · | · | |
| Net Income YoY | 4088.2% | · | · | · | · | · | · | · | · | · | · |
Valuation (TTM) 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $789.0K | $0 | $0 | $7M | $145M | $33M | $35M | $28M | $32M | $22M | $0 | |
| Net Income TTM | $6M | $136.0K | $-114M | $-250M | $-66M | $-89M | $-70M | $-99M | $-89M | $-92M | $-55M | |
| Market Cap | $142M | $2.88B | $3.78B | $14.02B | $15.31B | $44.82B | $4.84B | $3.70B | $8.23B | $7.99B | $27.43B | |
| Enterprise Value | · | · | $3.65B | $13.84B | · | $44.56B | · | · | · | · | · | |
| P/E | 23.2 | · | -1.6 | -48.5 | -231.4 | -437.5 | · | · | · | · | · | |
| P/S | 180.2 | · | · | 1967.6 | 105.6 | 1349.2 | 140.3 | 130.9 | 256.3 | 367.1 | · | |
| P/B | 3.2 | 208.6 | -84.3 | 1300.6 | 116.4 | 256.5 | -100.2 | -77.0 | 135.6 | 60.2 | 133.5 | |
| P / Tangible Book | 3.2 | 208.6 | · | 1300.6 | 116.4 | 256.5 | · | · | · | · | · | |
| P / Cash Flow | 127.3 | -19.3 | -32.2 | -61.3 | 2289.0 | -478.7 | -63.2 | -58.9 | -108.9 | 181.9 | -671.5 | |
| P / FCF | 164.4 | -19.3 | -30.2 | -58.8 | -5319.2 | -475.7 | -62.4 | -57.1 | -102.6 | 356.3 | -606.7 | |
| EV / EBITDA | · | · | -35.9 | -57.7 | · | -546.4 | · | · | · | · | · | |
| EV / FCF | · | · | -29.1 | -58.0 | · | -473.1 | · | · | · | · | · | |
| EV / Revenue | · | · | · | 1942.2 | · | 1341.6 | · | · | · | · | · | |
| Earnings Yield | 4.3% | 0.00% | -63.5% | -2.1% | -0.43% | -0.23% | · | · | · | · | · |
Income Statement 14
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $736.0K | $358.0K | $438.0K | $351.0K | $0 | $0 | $0 | $0 | $0 | $0 | $-126M | $310.0K | $126M | $-522.0K | · | $3M | |
| R&D Expense | $9M | $13M | $12M | $13M | $13M | $12M | $13M | $16M | $16M | $19M | $2M | $25M | $47M | $44M | $-17M | $43M | |
| SG&A Expense | $7M | $8M | $8M | $9M | $10M | $12M | $12M | $13M | $13M | $15M | $8M | $19M | $28M | $22M | $13M | $18M | |
| Operating Expenses | $22M | $21M | $20M | $23M | $25M | $27M | $29M | $29M | $29M | $34M | $4M | $45M | $77M | $70M | $-4M | $63M | |
| Operating Income | $-21M | $-21M | $-19M | $-22M | $-25M | $-27M | $-29M | $-29M | $-29M | $-34M | $-129M | $-45M | $50M | $-71M | $-2M | $-59M | |
| Interest Income | $181.0K | $325.0K | $445.0K | $618.0K | $546.0K | $618.0K | $437.0K | $652.0K | $1M | $2M | $2M | $3M | $2M | $1M | $1M | $865.0K | |
| Other Non-op | $673.0K | $669.0K | $2M | $3M | $4M | $7M | $6M | $-23M | $1M | $505.0K | $336.0K | $999.0K | $-2M | $310.0K | $-23.0K | $-33.0K | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $5M | $-20M | $-15M | $8M | $-20M | $33M | $-16M | $89M | $-33M | $-40M | $-41M | $-48M | $47M | $-71M | $-69M | $-60M | |
| EPS (Basic) | $0.47 | $-2.08 | $-1.79 | $0.94 | $-2.27 | $3.76 | $-1.80 | $11.63 | $-4.34 | $-5.49 | $-17.19 | $-0.37 | $0.36 | $-0.57 | $-0.51 | $-0.49 | |
| EPS (Diluted) | $0.47 | $-2.08 | $-1.78 | $0.94 | $-2.27 | $3.75 | $-1.80 | $11.63 | $-4.34 | $-5.49 | $-17.19 | $-0.37 | $0.36 | $-0.57 | $-0.51 | $-0.49 | |
| Shares (Basic) | 9,706,193 | 9,582,533 | -17,346,671 | 8,758,692 | 8,743,733 | 8,703,221 | -14,742,978 | 7,632,242 | 7,575,620 | 7,305,026 | -375,465,993 | 128,289,871 | 127,713,486 | 125,862,975 | -198,870,067 | 122,527,275 | |
| Shares (Diluted) | 9,747,138 | 9,582,533 | -17,360,211 | 8,771,519 | 8,743,733 | 8,714,701 | -14,742,978 | 7,632,242 | 7,575,620 | 7,305,026 | -377,597,438 | 128,289,871 | 129,844,931 | 125,862,975 | -198,870,067 | 122,527,275 | |
| EBITDA | $-21M | $-20M | · | $-21M | $-24M | $-26M | · | $-28M | $-30M | $-38M | · | $-46M | $51M | $-69M | · | $-57M |
Balance Sheet 25
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $16M | $30M | $46M | $48M | $45M | $59M | $31M | $67M | $71M | $111M | · | $170M | $230M | $95M | · | $205M | |
| Short-term Investments | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $12M | · | $28M | |
| Receivables | $274.0K | $233.0K | $157.0K | $351.0K | · | · | $0 | · | · | · | · | · | · | · | · | · | |
| Inventory | · | · | · | · | · | · | · | · | $53M | $42M | · | $19M | $5M | · | · | · | |
| Prepaid Expense | $1M | $2M | $3M | $3M | $2M | $4M | $6M | $6M | $6M | $5M | · | $9M | $9M | $10M | · | $15M | |
| Current Assets | $42M | $32M | $49M | $52M | $49M | $66M | $39M | $73M | $149M | $165M | · | $214M | $251M | $116M | · | $248M | |
| PP&E (Net) | $6M | $7M | $8M | $9M | $10M | $11M | $12M | $13M | $18M | $19M | · | $24M | $24M | $24M | · | $19M | |
| PP&E (Gross) | $61M | $64M | $64M | $65M | $65M | $65M | $65M | $65M | $72M | $72M | · | $73M | $72M | $71M | · | $65M | |
| Accum. Depreciation | $55M | $57M | $57M | $56M | $55M | $54M | $53M | $52M | $54M | $52M | · | $50M | $48M | $46M | · | $45M | |
| Other Non-current Assets | $31.0K | $31.0K | $31.0K | $31.0K | $31.0K | $31.0K | $31.0K | $465.0K | $42M | $41M | · | $12M | $11M | $11M | · | $12M | |
| Total Assets | $102M | $118M | $138M | $143M | $144M | $164M | $140M | $179M | $322M | $341M | · | $368M | $406M | $270M | · | $312M | |
| Accounts Payable | $1M | $2M | $2M | $2M | $2M | $2M | $4M | $8M | $5M | $5M | · | $9M | $13M | $12M | · | $10M | |
| Short-term Debt | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $0 | · | · | |
| Current Liabilities | $20M | $19M | $19M | $22M | $31M | $31M | $41M | $65M | $108M | $98M | · | $79M | $78M | $64M | · | $82M | |
| Capital Leases | $45M | $70M | $73M | $75M | $78M | $80M | $83M | $85M | $101M | $103M | · | $105M | $107M | $107M | · | $18M | |
| Other Non-current Liabilities | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | · | $2M | $2M | $1M | · | $961.0K | |
| Total Liabilities | $67M | $91M | $94M | $100M | $111M | $114M | $126M | $155M | $409M | $401M | · | $383M | $384M | $318M | · | $244M | |
| Long-term Debt | · | · | · | · | · | · | · | · | $110M | $110M | · | $110M | $110M | $50M | · | $50M | |
| Total Debt | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $0 | · | · | |
| Common Stock | $10.0K | $10.0K | $10.0K | $9.0K | $9.0K | $9.0K | $9.0K | $170.0K | $152.0K | $151.0K | · | $129.0K | $128.0K | $127.0K | · | $124.0K | |
| Retained Earnings | $-988M | $-992M | $-972M | $-957M | $-965M | $-945M | $-978M | $-962M | $-1.05B | $-1.02B | · | $-937M | $-889M | $-936M | · | $-796M | |
| AOCI | · | · | · | $0 | $0 | · | · | $0 | $0 | $0 | · | $0 | $-1.0K | $2.0K | · | $-118.0K | |
| Stockholders' Equity | $35M | $26M | $44M | $44M | $33M | $50M | $14M | $24M | $-87M | $-60M | $-45M | $-15M | $23M | $-48M | $11M | $68M | |
| Liabilities + Equity | $102M | $118M | $138M | $143M | $144M | $164M | $140M | $179M | $322M | $341M | · | $368M | $406M | $270M | · | $312M | |
| Shares Outstanding | 9,827,569 | 9,592,326 | 9,556,446 | 8,764,664 | 8,754,482 | 8,732,187 | 8,650,227 | 170,200,253 | 151,633,922 | 151,442,034 | 6,752,073 | 128,630,689 | 128,037,679 | 126,592,604 | 125,222,273 | 124,410,917 |
Cash Flow 11
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $670.0K | $781.0K | $954.0K | $1M | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $1M | $2M | $2M | |
| Stock-based Comp | $2M | $2M | $3M | $2M | $2M | $3M | $4M | $5M | $6M | $6M | $5M | $9M | $13M | $7M | $7M | $6M | |
| Restructuring | $0 | $914.0K | $0 | $1M | · | · | · | · | · | · | · | · | · | · | · | · | |
| Other Non-cash | · | $1M | · | · | · | $-10M | · | · | · | $-3M | · | · | · | $-14M | · | · | |
| Operating Cash Flow | $-22M | $-16M | $-15M | $2M | $-13M | $27M | $-39M | $-35M | $-40M | $-35M | $-47M | $-59M | $66M | $-77M | $-53M | $-60M | |
| CapEx | $0 | $0 | $29.0K | $8.0K | $181.0K | $34.0K | $90.0K | $129.0K | $99.0K | $62.0K | $877.0K | $2M | $1M | $4M | $3M | $1M | |
| Investing Cash Flow | $14.0K | $0 | $181.0K | $-8.0K | $-181.0K | $-34.0K | $-90.0K | $141M | $1M | $-62.0K | $-877.0K | $-2M | $11M | $3M | $6M | $40M | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $-3M | · | |
| Financing Cash Flow | $2M | $428.0K | $13M | $61.0K | $0 | $1M | $2M | $-111M | $0 | $19M | $6M | $1M | $58M | $6M | $5M | $98M | |
| Net Change in Cash | · | · | · | · | · | · | · | · | · | · | · | · | $135M | $-68M | · | $79M | |
| Free Cash Flow | · | $-16M | · | · | · | $27M | · | · | · | $-35M | · | · | · | $-81M | · | · |
Profitability 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -2890.3% | -5839.9% | · | -6403.7% | · | · | · | · | · | · | · | -15294.5% | 39.2% | 13518.8% | · | -1716.2% | |
| Net Margin | 622.4% | -5562.3% | · | 2337.3% | · | · | · | · | · | · | · | -15436.8% | 36.8% | 13634.9% | · | -1742.2% | |
| EBITDA Margin | -2799.3% | -5621.8% | · | -6106.3% | · | · | · | · | · | · | · | -14751.3% | 40.4% | 13250.6% | · | -1665.5% | |
| ROA | 3.7% | -14.1% | · | 5.1% | -8.5% | 12.9% | · | 32.5% | -9.0% | -13.1% | · | -14.1% | 13.7% | -24.1% | · | -17.0% | |
| ROE | 13.6% | -51.7% | · | 24.3% | 73.4% | -704.9% | · | 2018.6% | 102.0% | 74.6% | · | -182.4% | 203.8% | -430.2% | · | -49.3% |
Liquidity & Solvency 3
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.1 | 1.6 | · | 2.3 | 1.6 | 2.1 | · | 1.1 | 1.4 | 1.7 | · | 2.7 | 3.2 | 1.8 | · | 3.0 | |
| Quick Ratio | 0.8 | 1.6 | · | 2.1 | 1.5 | 1.9 | · | 1.0 | 0.7 | 1.1 | · | 2.1 | 2.9 | 1.7 | · | 2.8 | |
| Debt / Equity | · | · | · | · | · | · | · | · | · | · | · | 0.0 | 0.0 | 0.0 | · | · |
Efficiency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | · | · | · | · | 0.0 | 0.0 | · | 0.0 | 0.4 | -0.0 | · | 0.0 | |
| Receivables Turnover | 1.0 | 0.3 | · | 0.4 | · | · | · | · | · | · | · | · | · | · | · | · |
Valuation (TTM) 14
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $1M | · | · | · | $310.0K | $310.0K | · | $310.0K | $127M | $126M | · | $130M | $131M | $6M | · | $133M | |
| Net Income TTM | $-27M | $1M | · | $110M | $69M | $48M | · | $-32M | $-74M | $-113M | · | $-132M | $-149M | $-253M | · | $-113M | |
| Market Cap | $78M | $85M | · | $169M | $97M | $122M | · | $3.22B | $2.20B | $2.34B | · | $6.12B | $12.27B | $14.36B | · | $15.97B | |
| Enterprise Value | · | · | · | · | · | · | · | · | · | · | · | $5.95B | $12.04B | $14.25B | · | · | |
| P/E | -2.7 | 26.1 | · | 1.4 | 1.3 | 2.5 | · | 13.2 | -1.5 | -2.6 | · | -44.5 | -68.4 | -47.8 | · | -118.9 | |
| P/S | 53.7 | · | · | · | 313.7 | 394.4 | · | 10387.7 | 17.3 | 18.6 | · | 47.2 | 93.9 | 2549.4 | · | 120.2 | |
| P/B | 2.2 | 3.2 | · | 3.9 | 3.0 | 2.4 | · | 134.6 | -25.2 | -39.2 | · | -404.9 | 542.4 | -299.9 | · | 236.4 | |
| P / Tangible Book | 2.2 | 3.2 | · | 3.9 | 3.0 | 2.4 | · | 134.6 | · | · | · | · | 542.4 | · | · | 236.4 | |
| P / Cash Flow | · | -5.2 | · | · | · | 4.5 | · | · | · | -66.5 | · | · | · | -187.4 | · | · | |
| P / FCF | · | -5.2 | · | · | · | 4.5 | · | · | · | -66.4 | · | · | · | -178.0 | · | · | |
| EV / EBITDA | · | · | · | · | · | · | · | · | · | · | · | -130.2 | 235.8 | -206.0 | · | · | |
| EV / FCF | · | · | · | · | · | · | · | · | · | · | · | · | · | -176.7 | · | · | |
| EV / Revenue | · | · | · | · | · | · | · | · | · | · | · | 45.9 | 92.2 | 2530.5 | · | · | |
| Earnings Yield | -37.3% | 3.8% | · | 73.0% | 78.9% | 39.6% | · | 7.6% | -68.0% | -39.2% | · | -2.2% | -1.5% | -2.1% | · | -0.84% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | $789.0K | $0 | $0 | $7M | $145M |
| Operating Margin % | -11910.1% | — | -85.5% | -3458.1% | -44.5% |
| Net Income | $6M | $136.0K | $-114M | $-250M | $-66M |
| Diluted EPS | $0.64 | $0.00 | $-17.77 | $-2.31 | $-0.72 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Debt / Equity | — | — | 0.0 | 0.0 | — |
| Current Ratio | 2.6 | 0.9 | 1.8 | 2.3 | 3.7 |
| Quick Ratio | 2.4 | 0.7 | 1.3 | 2.1 | 3.5 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $865.0K | $-149M | $-125M | $-239M | $-3M |
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Institutional owners (13F) 43 filers · $15.5M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 13 (+10 vs prior Q) | 5 (-2 vs prior Q) | 6 (-3 vs prior Q) | 12 (+1 vs prior Q) | +240K |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| VANGUARD GROUP INC | $4,205,028 | 282,596 | 27.14% | Shares |
| Flagship Pioneering, LLC | $3,334,654 | 422,643 | 21.52% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $2,270,553 | 287,776 | 14.65% | Shares |
| Vontobel Holding Ltd. | $970,273 | 122,975 | 6.26% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $512,920 | 64,970 | 3.31% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $503,382 | 63,800 | 3.25% | Put option |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $460,208 | 58,328 | 2.97% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $384,125 | 48,685 | 2.48% | Shares |
| CITADEL ADVISORS LLC | $343,215 | 43,500 | 2.21% | Put option |
| HAP Trading, LLC | $334,750 | 125,000 | 2.16% | Call option |
| STATE STREET CORP | $267,479 | 33,901 | 1.73% | Shares |
| Lion Point Capital, LP | $249,087 | 31,570 | 1.61% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $244,977 | 31,049 | 1.58% | Shares |
| AMERICAN CENTURY COMPANIES INC | $223,390 | 28,313 | 1.44% | Shares |
| MARSHALL WACE, LLP | $217,606 | 27,580 | 1.40% | Shares |
| XTX Topco Ltd | $163,575 | 20,732 | 1.06% | Shares |
| GOLDMAN SACHS GROUP INC | $120,157 | 15,229 | 0.78% | Shares |
| NORTHERN TRUST CORP | $116,409 | 14,754 | 0.75% | Shares |
| Invesco Ltd. | $102,365 | 12,974 | 0.66% | Shares |
| MORGAN STANLEY | $93,978 | 11,911 | 0.61% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $87,579 | 11,100 | 0.57% | Call option |
| CITADEL ADVISORS LLC | $82,877 | 10,504 | 0.53% | Shares |
| SIMPLEX TRADING, LLC | $36,278 | 4,598 | 0.23% | Shares |
| SBI Securities Co., Ltd. | $32,996 | 4,182 | 0.21% | Shares |
| Integrated Wealth Concepts LLC | $31,560 | 4,000 | 0.20% | Shares |
| GROUP ONE TRADING LLC | $29,303 | 3,714 | 0.19% | Shares |
| JPMORGAN CHASE & CO | $25,832 | 3,316 | 0.17% | Shares |
| Vanguard Global Advisers, LLC | $15,583 | 1,975 | 0.10% | Shares |
| BlackRock, Inc. | $13,397 | 1,698 | 0.09% | Shares |
| Rachor Investment Advisory Services, LLC | $11,654 | 1,477 | 0.08% | Shares |
| UBS Group AG | $2,627 | 333 | 0.02% | Shares |
| Tower Research Capital LLC (TRC) | $2,493 | 316 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $1,665 | 211 | 0.01% | Shares |
| BARCLAYS PLC | $1,318 | 167 | 0.01% | Shares |
| FMR LLC | $773 | 98 | 0.00% | Shares |
| Continuum Advisory, LLC | $371 | 47 | 0.00% | Shares |
| MERCER GLOBAL ADVISORS INC /ADV | $292 | 37 | 0.00% | Shares |
| Sandy Spring Bank | $242 | 345 | 0.00% | Shares |
| WELLS FARGO & COMPANY/MN | $79 | 10 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $63 | 8 | 0.00% | Shares |
| Larson Financial Group LLC | $39 | 5 | 0.00% | Shares |
| WHITTIER TRUST CO OF NEVADA INC | $8 | 1 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $0 | 11 | 0.00% | Shares |
Company insiders 32 insiders · 16 officers · 17 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Richard N Kender | Interim Chief Executive Officer | July 8, 2026 A | 63,492 | 0 | 0 | $0 |
| Marella Thorell | EVP and Chief Financial Officer | July 8, 2026 A | — | 0 | 0 | $0 |
| David Arkowitz | Chief Financial Officer | Feb. 15, 2024 M | 182,442 | 0 | 0 | $0 |
| Matthew R. Henn | President and Chief Scientific Officer | Aug. 15, 2026 M | 7,995 | 0 | 5 | $-24,664 |
| Kelly Brady | EVP, Chief Operating Officer | Aug. 15, 2026 M | 8,679 | 0 | 2 | $-735 |
| Thomas Desrosier | EVP and Chief Legal Officer | Aug. 15, 2026 M | 8,117 | 0 | 5 | $-4,209 |
| Teresa L. Young | EVP, Chief Commercial & Strategy Officer | Feb. 15, 2026 M | 8,557 | 0 | 3 | $-19,644 |
| Lisa Von Moltke | Executive Vice President and Chief Medical Officer | Feb. 15, 2025 M | 39,875 | 0 | 0 | $0 |
| David S. Ege | Executive Vice President and Chief Technology Officer | Aug. 15, 2024 M | 77,575 | 0 | 0 | $0 |
| Paula Cloghessy | Executive Vice President, Chief People Officer | Oct. 27, 2023 M | 45,684 | 0 | 0 | $0 |
| Marcus Chapman | SVP, Principal Financial and Accounting Officer | Feb. 4, 2021 A | 8,600 | 0 | 0 | $0 |
| John G. Aunins | Chief Technology Officer & EVP | Jan. 29, 2020 A | 105,250 | 0 | 0 | $0 |
| David N Cook | Chief Scientific Officer and EVP of R&D | Jan. 26, 2019 M | 147,435 | 0 | 0 | $0 |
| Kevin Horgan | Chief Medical Officer and EVP | Jan. 25, 2019 A | — | 0 | 0 | $0 |
| Michele Trucksis | Chief Medical Officer and EVP | Jan. 30, 2018 A | 4,893 | 0 | 0 | $0 |
| Wael Hashad | EVP & Chief Commercial Officer | Jan. 26, 2017 A | — | 0 | 0 | $0 |
| Eric D. Shaff | Director | Aug. 15, 2026 M | 12,499 | 0 | 5 | $-12,708 |
| Stephen Berenson | Director | July 8, 2026 A | 3,589 | 0 | 0 | $0 |
| Robert L. Rosiello | Director | July 8, 2026 A | — | 0 | 0 | $0 |
| Kurt Graves | Director | July 8, 2026 A | — | 0 | 0 | $0 |
| Claire Fraser | Director | July 8, 2026 A | — | 0 | 0 | $0 |
| Dennis A Ausiello | Director | July 8, 2026 A | — | 0 | 0 | $0 |
| Willard H Dere | Director | July 8, 2026 A | 31,746 | 0 | 0 | $0 |
| Paul Biondi | Director | April 10, 2025 A | 47,619 | 0 | 0 | $0 |
| Hans-Juergen Woerle | Director | Feb. 4, 2025 A | — | 0 | 0 | $0 |
| Gregory Behar | Director | June 22, 2023 A | — | 0 | 0 | $0 |
| Meryl Zausner | Director | July 5, 2022 A | 31,746 | 0 | 0 | $0 |
| AFEYAN NOUBAR | Director | June 18, 2019 P | 4,444,444 | 0 | 0 | $0 |
| Lorence H. Kim | Director | June 13, 2019 A | — | 0 | 0 | $0 |
| Roger Pomerantz | Director | June 13, 2019 A | 213,976 | 0 | 0 | $0 |
| Peter Barton Hutt | Director | June 15, 2016 A | — | 0 | 0 | $0 |
| Werner Cautreels | Director | June 25, 2015 A | — | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 4 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Nestlé S.A., Société des Produits Nestlé S.A. | Oct. 2, 2024 | — | Initial filing | — | SEC |
| Nestle Health Science US Holdings, Inc., NIMCO US, Inc., Nestlé S.A., Nestlé US Holdco, Inc., Société des Produits Nestlé S.A. ×2 filings | July 22, 2022 | — | Initial filing | — | SEC |
| Flagship VentureLabs IV, LLC (2), Flagship Ventures Fund IV, L.P. (2), Flagship Ventures Fund IV-Rx, L.P. (2), Flagship Ventures Fund IV General Partner LLC (2), Nutritional Health LTP Fund, L.P. (2), Nutritional Health LTP Fund General Partner LLC (2), Flagship Pioneering Fund VI, L.P. (2), Flagship Pioneering Fund VI General Partner LLC (2), Flagship Pioneering Fund VII, L.P. (2), Flagship Pioneering Fund VII General Partner LLC (2), Flagship Pioneering, Inc. (2), Noubar B. Afeyan, Ph.D. (2) ×3 filings | July 7, 2022 | — | Initial filing | — | SEC |
| Nestle Health Science US Holdings, Inc. (1), NIMCO US, Inc. (1), Nestlé S.A., Nestlé US Holdco, Inc. (1), Société des Produits Nestlé S.A. | Aug. 19, 2020 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 8 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| IWC · iShares Trust | 0.01% | 25,389 SH | Aug. 8, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.00% | 12,905 SH | Aug. 8, 2026 | Daily |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.00% | 5,277 NS | May 31, 2026 | N-PORT |
| AVUV · AMERICAN CENTURY ETF TRUST | 0.00% | 37,364 NS | May 31, 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0.00% | 31,077 NS | May 31, 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0.00% | 1,022 NS | May 31, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.00% | 75,849 SH | Aug. 8, 2026 | Daily |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 206,170 SH | Aug. 8, 2026 | Daily |