ATYR aTyr Pharma, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$0.50
Price · May 20, 2026
Fundamentals as of Mar 5, 2026

ATYR Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$0.50
Market Cap
$77M
P/E (TTM)
-1.0
EPS (TTM)
$-0.80
Revenue (TTM)
$190.0K
Div Yield
ROE
-107.8%
Debt/Equity
52W Range
$0 – $7

ATYR Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $190.0K
7-point trend, -55.0%
2019-12-31 2025-12-31
EPS $-0.80
6-point trend, +54.8%
2020-12-31 2025-12-31
Free Cash Flow $-62M
10-point trend, -16.1%
2016-12-31 2025-12-31
Margins -39009.5%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
ATYR
Peer Median
P/E (TTM)
5-point trend, +76.8%
-1.0
0.9
P/S (TTM)
5-point trend, +9779.2%
404.0
2.0
P/B
5-point trend, -40.1%
1.1
2.3
Price / FCF
5-point trend, +80.2%
-1.2

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
ATYR
Peer Median
Operating Margin
5-point trend, -26745.6%
-40856.3%
Net Profit Margin
5-point trend, -25038.2%
-39009.5%
-350.0%
ROA
5-point trend, -78.4%
-78.1%
-69.7%
ROE
5-point trend, -125.0%
-107.8%
-112.4%
ROIC
5-point trend, -269.7%
-115.0%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
ATYR
Peer Median
Current Ratio
5-point trend, -72.0%
5.3
2.4
Quick Ratio
5-point trend, +82.5%
0.7

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
ATYR
Peer Median
Revenue YoY
5-point trend, +190000.00
-19.1%
Revenue CAGR 3Y
5-point trend, +190000.00
-73.7%
Revenue CAGR 5Y
5-point trend, +190000.00
-55.1%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
ATYR
Peer Median
EPS (Diluted)
5-point trend, +54.8%
$-0.80

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
ATYR
Peer Median

ATYR Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 16 analysts
  • Strong Buy 3 18.8%
  • Buy 5 31.2%
  • Hold 8 50.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

7 analysts · 2026-05-14
Median target $1.00 +98.9%
Mean target $4.36 +766.7%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.01%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.11 $-0.14 0.03%
Dec. 31, 2025 $-0.14 $-0.19 0.05%
Sept. 30, 2025 $-0.26 $-0.19 -0.07%
June 30, 2025 $-0.22 $-0.19 -0.03%
March 31, 2025 $-0.17 $-0.19 0.02%
Dec. 31, 2024 $-0.18 $-0.23 0.05%

Peer Comparison Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ATYR $77M -1.0 -19.1% -39009.5% -107.8%
BYSI 3.1%
INKT -3.8 4.5% -6931.8% 63.4%
ELUT 0.8 -15.0% 434.2% -753.4% 53.7%
XLO $3M -0.2 589.9% -80.0% -165.5%
ESLA -4.5
GOSS $724M -4.1 -57.7% -351.5% 201.8%
KALA $15M -0.2 -1423.8%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for ATYR
Metric Trend 2025202420232022202120202019
Revenue 7-point trend, -55.0% $190.0K $235.0K $353.0K $10M $0 $10M $422.0K
R&D Expense 7-point trend, +328.7% $60M $54M $42M $43M $23M $17M $14M
SG&A Expense 7-point trend, +88.2% $18M $14M $13M $14M $11M $9M $9M
Operating Expenses 7-point trend, +232.6% $78M $68M $55M $57M $34M $26M $23M
Operating Income 7-point trend, -237.8% $-78M $-68M $-55M $-46M $-34M $-16M $-23M
Other Non-op 7-point trend, +546.4% $4M $4M $5M $1M $238.0K $-319.0K $-785.0K
Pretax Income 7-point trend, -211.9% $-74M $-64M $-50M $-45M $-34M $-16M $-24M
Income Tax Flat — no change across 7 periods $0 $0 $0 $0 $0 $0 $0
Net Income 7-point trend, -356.8% $-74M $-64M $-50M $-45M $-34M $-16M $-16M
EPS (Basic) 6-point trend, +54.8% $-0.80 $-0.86 $-0.94 $-1.60 $-1.77 $-1.77 ·
EPS (Diluted) 6-point trend, +54.8% $-0.80 $-0.86 $-0.94 $-1.60 $-1.77 $-1.77 ·
Shares (Basic) 6-point trend, +915.1% 92,985,359 74,261,265 53,606,488 28,419,569 19,080,878 9,160,269 ·
Shares (Diluted) 6-point trend, +915.1% 92,985,359 74,261,265 53,606,488 28,419,569 19,080,878 9,160,269 ·
EBITDA 7-point trend, -244.5% $-77M $-67M $-54M $-46M $-34M $-15M $-22M
Balance Sheet 20
Annual Balance Sheet data for ATYR
Metric Trend 2025202420232022202120202019
Cash & Equivalents 7-point trend, +16.6% $11M $11M $23M $10M $2M $17M $9M
Prepaid Expense 7-point trend, -0.6% $677.0K $8M $2M $3M $5M $2M $681.0K
Current Assets 7-point trend, +151.3% $80M $82M $103M $81M $114M $36M $32M
PP&E (Net) 7-point trend, +235.7% $4M $5M $6M $3M $543.0K $899.0K $1M
PP&E (Gross) 7-point trend, +21.5% $9M $9M $10M $9M $7M $8M $7M
Accum. Depreciation 7-point trend, -22.3% $5M $5M $5M $6M $6M $7M $6M
Other Non-current Assets 7-point trend, -14.0% $148.0K $66.0K $131.0K $193.0K $158.0K $213.0K $172.0K
Total Assets 7-point trend, +157.0% $93M $97M $121M $96M $116M $39M $36M
Accounts Payable 7-point trend, +359.4% $4M $4M $4M $3M $1M $1M $847.0K
Accrued Liabilities 7-point trend, +312.1% $10M $9M $12M $10M $4M $4M $2M
Current Liabilities 7-point trend, +17.2% $15M $15M $16M $14M $6M $6M $13M
Capital Leases 7-point trend, +360.4% $10M $11M $12M $10M $398.0K $1M $2M
Total Debt · · · · · · $9M
Common Stock 7-point trend, +2350.0% $98.0K $84.0K $63.0K $29.0K $28.0K $11.0K $4.0K
Paid-in Capital 7-point trend, +96.1% $674M $602M $559M $490M $482M $370M $344M
Retained Earnings 7-point trend, -88.1% $-606M $-532M $-468M $-418M $-372M $-339M $-322M
AOCI 7-point trend, +80.0% $-8.0K $-40.0K $-74.0K $-433.0K $-263.0K $-43.0K $-40.0K
Stockholders' Equity 7-point trend, +218.5% $67M $70M $91M $71M $109M $32M $21M
Liabilities + Equity 7-point trend, +157.0% $93M $97M $121M $96M $116M $39M $36M
Shares Outstanding 7-point trend, +2418.9% 98,031,104 84,038,922 63,286,404 29,498,488 27,793,035 11,018,954 3,891,787
Cash Flow 8
Annual Cash Flow data for ATYR
Metric Trend 2025202420232022202120202019
D&A 7-point trend, +4.6% $664.0K $708.0K $592.0K $232.0K $475.0K $569.0K $635.0K
Other Non-cash 7-point trend, +288.1% $11M $-6M $17M $3M $218.0K $354.0K $3M
Operating Cash Flow 7-point trend, -209.7% $-62M $-69M $-33M $-42M $-33M $-15M $-20M
CapEx 7-point trend, -2.5% $77.0K $65.0K $4M $2M $192.0K $202.0K $79.0K
Investing Cash Flow 7-point trend, -202.6% $-5M $17M $-20M $47M $-92M $7M $5M
Financing Cash Flow 7-point trend, +4840.9% $66M $40M $66M $5M $110M $16M $1M
Net Change in Cash 7-point trend, +92.5% $-1M $-12M $13M $11M $-15M $8M $-14M
Free Cash Flow 7-point trend, -208.9% $-62M $-69M $-37M $-44M $-33M $-16M $-20M
Profitability 7
Annual Profitability data for ATYR
Metric Trend 2025202420232022202120202019
Operating Margin 6-point trend, -650.3% -40856.3% -28899.6% -15557.8% -446.8% · -152.2% -5445.0%
Net Margin 6-point trend, -597.5% -39009.5% -27243.8% -14274.5% -436.5% · -155.2% -5593.1%
Pretax Margin 6-point trend, -592.8% -39012.1% -27243.4% -14276.2% -436.6% · -155.2% -5631.0%
EBITDA Margin 6-point trend, -665.1% -40506.8% -28598.3% -15390.1% -444.6% · -146.7% -5294.6%
ROA 7-point trend, -47.1% -78.1% -58.9% -46.6% -42.9% -43.8% -43.3% -53.1%
ROE 7-point trend, -9.4% -107.8% -79.7% -62.2% -50.2% -47.9% -61.4% -98.5%
ROIC 6-point trend, -128.8% -115.0% -97.0% -60.6% -64.9% -31.1% -50.3% ·
Liquidity & Solvency 3
Annual Liquidity & Solvency data for ATYR
Metric Trend 2025202420232022202120202019
Current Ratio 7-point trend, +114.4% 5.3 5.5 6.3 5.8 18.9 6.1 2.5
Quick Ratio 7-point trend, -0.5% 0.7 0.7 1.4 0.7 0.4 2.9 0.7
Debt / Equity · · · · · · 0.4
Efficiency 1
Annual Efficiency data for ATYR
Metric Trend 2025202420232022202120202019
Asset Turnover 6-point trend, -78.9% 0.0 0.0 0.0 0.1 · 0.3 0.0
Per Share 5
Annual Per Share data for ATYR
Metric Trend 2025202420232022202120202019
Book Value / Share 7-point trend, -87.4% $0.69 $0.83 $1.43 $2.42 $3.93 $2.87 $5.44
Revenue / Share 4-point trend, -99.5% $0.00 $0.00 $0.01 $0.37 · · ·
Cash Flow / Share 4-point trend, +54.8% $-0.67 $-0.93 $-0.62 $-1.47 · · ·
Cash / Share 7-point trend, -95.4% $0.11 $0.13 $0.36 $0.34 $0.08 $1.54 $2.37
EPS (TTM) 6-point trend, +54.8% $-0.80 $-0.86 $-0.94 $-1.60 $-1.77 $-1.77 ·
Growth Rates 3
Annual Growth Rates data for ATYR
Metric Trend 2025202420232022202120202019
Revenue YoY 3-point trend, +80.2% -19.1% -33.4% -96.6% · · · ·
Revenue CAGR 3Y 2-point trend, -8.8% -73.7% · -67.7% · · · ·
Revenue CAGR 5Y -55.1% · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for ATYR
Metric Trend 2025202420232022202120202019
Revenue TTM 7-point trend, -55.0% $190.0K $235.0K $353.0K $10M $0 $10M $422.0K
Net Income TTM 7-point trend, -356.8% $-74M $-64M $-50M $-45M $-34M $-16M $-16M
Market Cap 7-point trend, +373.0% $77M $304M $89M $65M $208M $43M $16M
Enterprise Value · · · · · · $16M
P/E 6-point trend, +55.3% -1.0 -4.2 -1.5 -1.4 -4.2 -2.2 ·
P/S 6-point trend, +950.5% 404.0 1294.6 252.8 6.2 · 4.1 38.5
P/B 7-point trend, +48.5% 1.1 4.3 1.0 0.9 1.9 1.4 0.8
P / Tangible Book 6-point trend, -15.8% 1.1 4.3 1.0 0.9 1.9 1.4 ·
P / Cash Flow 7-point trend, -52.7% -1.2 -4.4 -2.7 -1.5 -6.3 -2.8 -0.8
P / FCF 7-point trend, -53.1% -1.2 -4.4 -2.4 -1.5 -6.2 -2.8 -0.8
EV / EBITDA · · · · · · -0.7
EV / FCF · · · · · · -0.8
EV / Revenue · · · · · · 37.3
Earnings Yield 6-point trend, -124.0% -102.2% -23.8% -66.7% -73.1% -23.7% -45.6% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $190.0K$235.0K$353.0K$10M$0
Operating Margin % -40856.3%-28899.6%-15557.8%-446.8%
Net Income $-74M$-64M$-50M$-45M$-34M
Diluted EPS $-0.80$-0.86$-0.94$-1.60$-1.77
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 5.35.56.35.818.9
Quick Ratio 0.70.71.40.70.4
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-62M$-69M$-37M$-44M$-33M

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