SEPN logo
SEPN NASDAQ US

Septerna, Inc. - Common Stock

Healthcare · Pharmaceuticals Website · IPO Oct 2024
$25.18
▲ +$0.81 (+3.32%)
Vol 288K
3
Quality Score
fail
Mkt Cap
$1.2B
Margin
-266.8%
D/E
0.00
Beta
2.38
52W
$4–$31

Wall Street Consensus

14 analysts · Apr 2026
3
Strong Buy
10
Buy
1
Hold
0
Sell
0
Strong Sell
92.9%
Buy Rating

Price Chart

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Earnings

Beat rate: 25.0%
Next Report May 13, 2026
EPS Estimate: $-0.37
Quarter EPS Est EPS Act Surprise
Mar 2026 $-0.37 — —
Dec 2025 $-0.26 $-0.24 +$0.02
Sep 2025 $0.81 $-0.09 $-0.90
Jun 2025 $0.88 $-0.56 $-1.44

Fundamentals Trend

Metric 2025-06-30 2025-09-02 2025-10-02 2025-11-03 2025-12-03 2026-01-02
ROE (TTM) — — — — — —
P/E (TTM) — — — — — —
Net Margin -20872.3% -12053.0% -12053.0% -12053.0% -266.8% -266.8%
Gross Margin — — — — — —
D/E Ratio — 0.00 0.00 0.00 0.00 0.00
Current Ratio — 27.77 27.77 27.77 27.77 27.77

Key Ratios

P/S (TTM)
56.63
P/B
2.4
EPS (TTM)
$-1.51
52W High
$30.50
52W Low
$4.17
$4.17 52-Week Range $30.50

How does SEPN compare to Pharmaceuticals peers?

Peer group: Micro-cap Pharmaceuticals (All) · 171 companies

SEPN AARD ACB ACRS ADIL

SEPN valuation vs Pharmaceuticals peers

P/E ratio
—
▼ 0% below peers (22.4)
vs Peers
vs Industry
Undervalued
P/S ratio
56.6
▲ 1044% above peers (5.0)
vs Peers
vs Industry
Overvalued
P/B ratio
2.4
▲ 14% above peers (2.1)
vs Peers
vs Industry
Fair value
Div yield
—
▼ 0% below peers (2.0%)
vs Peers
vs Industry
Low yield

SEPN profitability vs Pharmaceuticals peers

ROE
—
▼ 0% below peers (-54.3%)
vs Peers
vs Industry
Top tier
Net margin
-266.8%
▼ 463% below peers (-47.4%)
vs Peers
vs Industry
Weak
Gross margin
—
▼ 0% below peers (68.3%)
vs Peers
vs Industry
In line
ROA
—
▼ 0% below peers (-37.4%)
vs Peers
vs Industry
Top tier

SEPN financial health vs Pharmaceuticals peers

D/E ratio
0.0
▼ 100% below peers (1.5)
vs Peers
vs Industry
Low debt
Current ratio
27.8
▲ 727% above peers (3.4)
vs Peers
vs Industry
Strong liquidity
Beta
2.4
▲ 153% above peers (0.9)
vs Peers
vs Industry
More volatile

SEPN fundamentals radar

SEPN Peer median Industry

SEPN profitability vs leverage

Bubble size = market cap · X = net margin · Y = D/E ratio

SEPN vs peers: key metrics

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