EYPT EyePoint, Inc. - Common Stock

NASDAQ · Pharmaceuticals · View on SEC EDGAR ↗
$5.96
Price · Aug 19, 2026
Fundamentals as of Aug 5, 2026

About EyePoint, Inc. - Common Stock Company overview from Wikipedia

EyePoint Pharmaceuticals Inc. is a Watertown, Massachusetts company specialising in the application of microelectromechanical systems (MEMS) and nanotechnology to drug delivery.

Read more

EyePoint Pharmaceuticals Inc. (formerly pSivida Corporation) is a Watertown, Massachusetts company specialising in the application of microelectromechanical systems (MEMS) and nanotechnology to drug delivery.

pSivida obtained porous silicon technology from the British government Defence Evaluation and Research Agency (DERA, now QinetiQ). QinetiQ continues to be a strategic partner.

In June 2004, pSivida acquired full ownership of pSiMedica. In April 2018, pSivida purchased eye products firm Icon Bioscience. Afterwards, it rebranded to its current name of EyepOint Pharmaceuticals, Inc.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

EYPT Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$5.96
Market Cap
$494M
P/E (TTM)
-1.9
EPS (TTM)
$-3.17
Revenue (TTM)
$31M
Div Yield
ROE
-84.0%
Debt/Equity
52W Range
$4 – $19

EYPT Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $31M
10-point trend, +316.1%
2017-06-30 2025-12-31
EPS $-3.17
6-point trend, -509.6%
2017-06-30 2025-12-31
Free Cash Flow $-243M
6-point trend, -327.7%
2019-12-31 2025-12-31
Margins -739.4%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
EYPT
Peer Median
P/E (TTM)
5-point trend, +4.4%
-1.9
29.9
P/S (TTM)
5-point trend, +329.3%
15.7
14.4
P/B
5-point trend, +119.6%
1.6
4.4
Price / FCF
5-point trend, +24.7%
-2.0

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
EYPT
Peer Median
Operating Margin
5-point trend, -418.6%
-776.0%
Net Profit Margin
5-point trend, -367.6%
-739.4%
0.70%
ROA
5-point trend, -80.2%
-59.3%
-0.55%
ROE
5-point trend, -99.3%
-84.0%
-2.5%
ROIC
5-point trend, -218.2%
-79.6%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
EYPT
Peer Median
Current Ratio
5-point trend, -11.7%
8.9
3.9
Quick Ratio
5-point trend, -7.5%
8.3

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
EYPT
Peer Median
Revenue YoY
5-point trend, -15.1%
-27.5%
Revenue CAGR 3Y
5-point trend, -15.1%
-8.8%
Revenue CAGR 5Y
5-point trend, -15.1%
-1.8%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
EYPT
Peer Median
EPS (Diluted)
5-point trend, -56.2%
$-3.17

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
EYPT
Peer Median

EYPT Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 20 analysts
  • Strong Buy 7 35.0%
  • Buy 12 60.0%
  • Hold 1 5.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

13 analysts · 2026-08-19
Median target $37.00 +520.8%
Mean target $36.62 +514.4%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.07%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-1.09 $-0.97 -0.12%
March 31, 2026 $-0.99 $-0.82 -0.17%
Dec. 31, 2025 $-0.81 $-0.76 -0.05%
Sept. 30, 2025 $-0.85 $-0.80 -0.05%
June 30, 2025 $-0.85 $-0.81 -0.04%
March 31, 2025 $-0.65 $-0.67 0.02%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
EYPT $1.51B -5.8 -27.5% -739.4% -84.0%
AQST $788M -8.3 -22.6% -188.1% 157.7%
CTNM -5.3 -27.7%
ZVRA $509M 6.6 350.9% 78.2% 61.2%
EOLS $432M -8.3 11.6% -17.4% 247.3% 66.3%
RLMD $354M -3.3 93.7% -112.0%
BIOA $495M -5.9 -896.1% -28.4%
AVIR $279M -1.8 -49.5%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for EYPT
Metric Trend 20252024202320222021202020192018201720162015
Revenue 11-point trend, +18.1% $31M $43M $46M $41M $37M $34M $20M $5M $8M $2M $27M
R&D Expense 11-point trend, +1728.6% $221M $133M $65M $50M $28M $17M $15M $19M $15M $14M $12M
SG&A Expense 11-point trend, +540.6% $52M $52M $40M $35M $26M $21M $18M $15M $11M $9M $8M
Operating Expenses 11-point trend, +1264.2% $275M $189M $121M $141M $92M $72M $68M $44M $26M $23M $20M
Operating Income 11-point trend, -3891.2% $-243M $-146M $-75M $-100M $-55M $-37M $-48M $-39M $-19M $-22M $6M
Interest Expense 8-point trend, +1247000.00 · · $1M $3M $5M $7M $6M $2M $0 $0 ·
Interest Income · · · · · · · · · · $19.0K
Other Non-op 11-point trend, +53463.6% $12M $15M $7M $2M $292.0K $58.0K $1M $420.0K $91.0K $72.0K $22.0K
Pretax Income 10-point trend, -3695.9% $-232M $-131M $-71M $-102M $-58M $-45M $-57M · $-18M $-22M $6M
Income Tax 9-point trend, +190.6% $279.0K $90.0K $83.0K · $0 $0 $0 · $0 $-155.0K $96.0K
Net Income 11-point trend, -3754.7% $-232M $-131M $-71M $-102M $-58M $-45M $-57M $-86M $-18M $-22M $6M
EPS (Basic) 8-point trend, -1540.9% $-3.17 $-2.32 $-1.82 $-2.74 $-2.03 · · · $-0.52 $-0.68 $0.22
EPS (Diluted) 8-point trend, -1609.5% $-3.17 $-2.32 $-1.82 $-2.74 $-2.03 · · · $-0.52 $-0.68 $0.21
Shares (Basic) 8-point trend, -99.8% 73,251 56,298 38,904 37,317,000 28,758,000 · · · 35,343,765 31,623,473 29,378,250
Shares (Diluted) 8-point trend, -99.8% 73,251 56,298 38,904 37,317,000 28,758,000 · · · 35,343,765 31,623,473 30,584,140
EBITDA 8-point trend, -3855.3% $-241M $-146M $-75M $-100M $-55M · $-48M · · $-22M $6M
Balance Sheet 27
Annual Balance Sheet data for EYPT
Metric Trend 20252024202320222021202020192018201720162015
Cash & Equivalents 11-point trend, +432.5% $102M $100M $281M $96M $179M $45M $22M $45M $17M $15M $19M
Short-term Investments 11-point trend, +2069.8% $204M $271M $50M $49M $33M $0 $0 $0 $0 $14M $9M
Inventory 8-point trend, +549.8% $2M $2M $4M $3M $4M $5M $2M $279.0K · · ·
Prepaid Expense 11-point trend, +2852.3% $20M $9M $9M $10M $4M $3M $6M $1M $591.0K $483.0K $681.0K
Other Current Assets 5-point trend, +279.9% $2M $1M $1M $782.0K $517.0K · · · · · ·
Current Assets 11-point trend, +1001.5% $329M $383M $345M $173M $238M $63M $42M $48M $18M $30M $30M
PP&E (Net) 11-point trend, +2569.5% $9M $8M $5M $1M $476.0K $630.0K $357.0K $288.0K $313.0K $290.0K $338.0K
PP&E (Gross) 11-point trend, +601.5% $15M $12M $8M $3M $2M $2M $1M $983.0K $799.0K $2M $2M
Accum. Depreciation 11-point trend, +233.2% $6M $4M $3M $2M $1M $1M $839.0K $695.0K $486.0K $2M $2M
Intangibles 8-point trend, -100.0% · · · $0 $23M $25M $28M $30M $364.0K $1M $2M
Other Non-current Assets 3-point trend, +5945000.00 $6M $6M $0 · · · · · · · ·
Total Assets 11-point trend, +1024.6% $364M $418M $355M $180M $263M $92M $73M $78M $19M $32M $32M
Accounts Payable 11-point trend, +1309.9% $10M $12M $7M $6M $7M $5M $4M $3M $1M $1M $744.0K
Accrued Liabilities 11-point trend, +848.8% $24M $18M $18M $16M $14M $8M $7M $4M $4M $4M $3M
Short-term Debt 3-point trend, +0.00 · · $0 $10M $0 · · · · · ·
Current Liabilities 11-point trend, +1005.9% $37M $49M $63M $35M $24M $15M $12M $21M $5M $5M $3M
Capital Leases 8-point trend, +20772000.00 $21M $22M $5M $6M $2M $2M $3M $0 · · ·
Other Non-current Liabilities 9-point trend, +70.6% $87.0K $205.0K $0 $600.0K $2M $2M $3M $1M $51.0K · ·
Total Liabilities 11-point trend, +543.2% $58M $82M $89M $84M $79M $73M $65M $41M $5M $11M $9M
Long-term Debt · · · $30M · · · · · · ·
Total Debt 4-point trend, -100.0% · · $0 $40M $37M · $47M · · · ·
Common Stock 11-point trend, +186.2% $83.0K $68.0K $49.0K $34.0K $34.0K $18.0K $11.0K $95.0K $39.0K $34.0K $29.0K
Retained Earnings 11-point trend, -308.2% $-1.10B $-873M $-742M $-671M $-569M $-511M $-465M $-408M $-311M $-292M $-271M
AOCI 11-point trend, +1.7% $961.0K $1M $864.0K $786.0K $841.0K $841.0K $840.0K $839.0K $833.0K $852.0K $945.0K
Stockholders' Equity 11-point trend, +1210.0% $306M $337M $266M $96M $184M $19M $8M $38M $13M $21M $23M
Liabilities + Equity 11-point trend, +1024.6% $364M $418M $355M $180M $263M $92M $73M $78M $19M $32M $32M
Shares Outstanding 11-point trend, +181.6% 82,826,416 68,266,005 49,043,074 34,082,934 33,905,826 18,139,981 10,941,659 95,372,236 39,356,999 34,172,919 29,412,365
Cash Flow 18
Annual Cash Flow data for EYPT
Metric Trend 20252024202320222021202020192018201720162015
D&A 3-point trend, +397.6% $2M $2M $464.0K · · · · · · · ·
Stock-based Comp 10-point trend, +1321.4% $28M $37M $12M $14M $7M $6M $5M · $2M $2M $2M
Deferred Tax 3-point trend, +236.1% $279.0K $90.0K $83.0K · · · · · · · ·
Amort. of Intangibles 9-point trend, -100.0% · · $0 $2M $2M $2M $2M $981.0K $724.0K $756.0K $770.0K
Restructuring 2-point trend, +25.0% · · · · · $590.0K · · $472.0K · ·
Other Non-cash $-39M · · · · · · · · · ·
Operating Cash Flow 10-point trend, -2431.8% $-240M $-126M $2M $-65M $-50M $-14M $-57M · $-20M $-16M $10M
CapEx 10-point trend, +1937.3% $3M $4M $3M $2M $156.0K $362.0K $213.0K · $147.0K $113.0K $161.0K
Investing Cash Flow 9-point trend, +1637.0% $69M $-219M $-3M $-17M $-33M $-362.0K $-213.0K · $14M $-4M ·
Debt Issued 6-point trend, +0.00 · · $0 $30M $0 · $50M · $0 $0 ·
Net Debt Issued 5-point trend, -100.0% · $0 $-30M $-8M $0 · $30M · · · ·
Stock Issued 9-point trend, +173445000.00 $173M $163M $226M $0 · $50M $23M · $8M $16M $0
Net Stock Activity 5-point trend, +951.2% $173M $163M $226M · · · $23M · · $16M ·
Financing Cash Flow 9-point trend, +922.1% $174M $164M $187M $-690.0K $217M $37M $34M · $9M $17M ·
Net Change in Cash 10-point trend, -44.1% $2M $-182M $186M $-83M $134M $23M $-23M · $2M $-4M $4M
Taxes Paid 2-point trend, +100.0% $200.0K $100.0K · · · · · · · · ·
Free Cash Flow 8-point trend, -2501.2% $-243M $-130M $-2M $-67M $-50M · $-57M · · $-16M $10M
Levered FCF 4-point trend, +95.5% · · $-3M $-70M $-56M · $-63M · · · ·
Profitability 7
Annual Profitability data for EYPT
Metric Trend 20252024202320222021202020192018201720162015
Operating Margin 8-point trend, -3310.5% -776.0% -337.1% -163.1% -240.6% -149.6% · -235.0% · · -1344.1% 24.2%
Net Margin 8-point trend, -3195.1% -739.4% -302.4% -153.8% -247.0% -158.1% · -278.9% · · -1330.1% 23.9%
Pretax Margin 8-point trend, -3145.5% -738.5% -302.2% -153.7% -247.0% -158.1% · -278.9% · · -1339.6% 24.2%
EBITDA Margin 8-point trend, -3280.1% -768.6% -337.1% -163.1% -240.6% -149.6% · -235.0% · · -1344.1% 24.2%
ROA 8-point trend, -357.1% -59.3% -33.8% -26.4% -46.1% -32.9% · -75.1% · · -67.3% 23.1%
ROE 8-point trend, -439.0% -84.0% -47.1% -43.6% -87.9% -42.2% · -468.1% · · -90.8% 24.8%
ROIC 8-point trend, -394.1% -79.6% -43.4% -28.2% -73.2% -25.0% · -86.2% · · -103.5% 27.1%
Liquidity & Solvency 5
Annual Liquidity & Solvency data for EYPT
Metric Trend 20252024202320222021202020192018201720162015
Current Ratio 8-point trend, -0.4% 8.9 7.8 5.5 5.0 10.0 · 3.6 · · 5.9 8.9
Quick Ratio 8-point trend, -3.0% 8.3 7.6 5.2 4.2 8.9 · 1.9 · · 5.7 8.5
Debt / Equity 4-point trend, -100.0% · · 0.0 0.4 0.2 · 5.7 · · · ·
LT Debt / Equity 3-point trend, -94.6% · · · 0.3 0.2 · 5.7 · · · ·
Interest Coverage 4-point trend, -676.8% · · -60.2 -31.2 -10.1 · -7.7 · · · ·
Efficiency 1
Annual Efficiency data for EYPT
Metric Trend 20252024202320222021202020192018201720162015
Asset Turnover 8-point trend, -91.7% 0.1 0.1 0.2 0.2 0.2 · 0.3 · · 0.1 1.0
Per Share 5
Annual Per Share data for EYPT
Metric Trend 20252024202320222021202020192018201720162015
Book Value / Share 8-point trend, +365.2% $3.70 $4.93 $5.43 $2.83 $5.44 · $0.08 · · $0.61 $0.79
Revenue / Share 6-point trend, +49205.5% $428.27 $768.64 $1.18 $1.11 · · · · · $0.05 $0.87
Cash Flow / Share 6-point trend, -973639.5% $-3277.91 $-2242.10 $0.05 $-1.74 · · · · · $-0.52 $0.34
Cash / Share 8-point trend, +89.1% $1.23 $1.46 $5.74 $2.81 $5.27 · $0.20 · · $0.45 $0.65
EPS (TTM) 10-point trend, -1609.5% $-3.17 $-2.32 $-1.82 $-2.74 $-2.03 $-0.67 $-0.67 · $-0.52 $-0.68 $0.21
Growth Rates 3
Annual Growth Rates data for EYPT
Metric Trend 20252024202320222021202020192018201720162015
Revenue YoY 5-point trend, -478.3% -27.5% -6.0% 11.1% 12.1% 7.3% · · · · · ·
Revenue CAGR 3Y 3-point trend, -187.0% -8.8% 5.4% 10.2% · · · · · · · ·
Revenue CAGR 5Y -1.8% · · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for EYPT
Metric Trend 20252024202320222021202020192018201720162015
Revenue TTM 10-point trend, +18.1% $31M $43M $46M $41M $37M $34M $20M · $8M $2M $27M
Net Income TTM 10-point trend, -3754.7% $-232M $-131M $-71M $-102M $-58M $-45M $-57M · $-18M $-22M $6M
Market Cap 8-point trend, +36.5% $1.51B $509M $1.13B $119M $415M · $1.70B · · $967M $1.11B
Enterprise Value 4-point trend, -53.4% · · $802M $15M $240M · $1.72B · · · ·
P/E 10-point trend, -103.2% -5.8 -3.2 -12.7 -1.3 -6.0 -9.8 -23.1 · -32.9 -41.6 179.5
P/S 8-point trend, +15.6% 48.2 11.8 24.6 2.9 11.2 · 83.3 · · 597.0 41.7
P/B 8-point trend, -89.6% 4.9 1.5 4.3 1.2 2.3 · 203.6 · · 46.3 47.5
P / Tangible Book 5-point trend, +92.5% 4.9 1.5 4.3 1.2 2.6 · · · · · ·
P / Cash Flow 8-point trend, -105.9% -6.3 -4.0 604.5 -1.8 -8.3 · -29.9 · · -59.3 107.7
P / FCF 8-point trend, -105.7% -6.2 -3.9 -704.8 -1.8 -8.3 · -29.8 · · -58.9 109.4
EV / EBITDA 4-point trend, +70.3% · · -10.7 -0.1 -4.3 · -36.0 · · · ·
EV / FCF 4-point trend, -1550.1% · · -499.0 -0.2 -4.8 · -30.2 · · · ·
EV / Revenue 4-point trend, -79.4% · · 17.4 0.4 6.5 · 84.5 · · · ·
Earnings Yield 10-point trend, -3198.2% -17.3% -31.1% -7.9% -78.3% -16.6% -10.2% -4.3% · -3.0% -2.4% 0.56%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $31M$43M$46M$41M$37M
Operating Margin % -776.0%-337.1%-163.1%-240.6%-149.6%
Net Income $-232M$-131M$-71M$-102M$-58M
Diluted EPS $-3.17$-2.32$-1.82$-2.74$-2.03
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.00.40.2
Current Ratio 8.97.85.55.010.0
Quick Ratio 8.37.65.24.28.9
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-243M$-130M$-2M$-67M$-50M

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Institutional owners (13F) 217 filers · $1.2B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
37 (-25 vs prior Q) 21 (-2 vs prior Q) 63 (-9 vs prior Q) 56 (+18 vs prior Q) +3.1M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
MONTANOVA CAPITAL, LLC $118,638,163 8,296,375 10.19% Shares
Cormorant Asset Management, LP $100,100,000 7,000,000 8.60% Shares
VANGUARD GROUP INC $78,353,343 4,288,634 6.73% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $69,037,426 4,827,792 5.93% Shares
Commodore Capital LP $65,780,000 4,600,000 5.65% Shares
VANGUARD CAPITAL MANAGEMENT LLC $51,912,604 3,630,252 4.46% Shares
JANUS HENDERSON GROUP PLC $45,962,750 3,565,768 3.95% Shares
Paradigm Biocapital Advisors LP $41,332,677 2,890,397 3.55% Shares
STATE STREET CORP $33,712,894 2,357,545 2.90% Shares
Aberdeen Group plc $28,725,869 2,008,802 2.47% Shares
PERCEPTIVE ADVISORS LLC $28,600,000 2,000,000 2.46% Put option
Balyasny Asset Management L.P. $25,916,719 1,812,358 2.23% Shares
GEODE CAPITAL MANAGEMENT, LLC $25,269,659 1,766,745 2.17% Shares
CITADEL ADVISORS LLC $25,214,389 1,763,244 2.17% Shares
Parkman Healthcare Partners LLC $18,420,731 1,288,163 1.58% Shares
EVENTIDE ASSET MANAGEMENT, LLC $17,811,837 1,245,583 1.53% Shares
TWO SIGMA INVESTMENTS, LP $16,890,345 1,181,143 1.45% Shares
Essex Woodlands Management, Inc. $15,513,455 1,084,857 1.33% Shares
ORBIMED ADVISORS LLC $15,288,802 1,069,147 1.31% Shares
5AM Venture Management, LLC $15,015,000 1,050,000 1.29% Shares
Rosalind Advisors, Inc. $14,131,689 988,230 1.21% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $13,885,500 971,014 1.19% Shares
HSBC HOLDINGS PLC $11,918,407 833,455 1.02% Shares
Candriam S.C.A. $11,254,258 787,769 0.97% Shares
AMERIPRISE FINANCIAL INC $11,087,640 775,357 0.95% Shares
DIMENSIONAL FUND ADVISORS LP $11,062,981 773,635 0.95% Shares
Artia Global Partners LP $10,969,501 767,098 0.94% Shares
Blue Owl Capital Holdings LP $10,905,094 762,594 0.94% Shares
Patient Square Capital LP $10,296,000 720,000 0.88% Shares
Principia Wealth Advisory, LLC $9,696,346 530,725 0.83% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $9,260,866 647,613 0.80% Shares
Sio Capital Management, LLC $8,910,759 623,130 0.77% Shares
VANGUARD FIDUCIARY TRUST CO $7,996,789 559,216 0.69% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $7,899,320 552,400 0.68% Call option
Alyeska Investment Group, L.P. $7,284,463 509,403 0.63% Shares
MILLENNIUM MANAGEMENT LLC $7,151,330 500,093 0.61% Shares
Simplify Asset Management Inc. $5,720,629 400,044 0.49% Shares
Ikarian Capital, LLC $5,296,720 370,400 0.46% Call option
Ikarian Capital, LLC $5,296,720 370,400 0.46% Put option
Ghisallo Capital Management LLC $5,005,000 350,000 0.43% Shares
STEMPOINT CAPITAL LP $4,840,135 338,471 0.42% Shares
E Fund Management Co., Ltd. $4,730,068 330,774 0.41% Shares
Jump Financial, LLC $4,586,825 320,757 0.39% Shares
Bleichroeder LP $4,526,165 316,515 0.39% Shares
Woodline Partners LP $4,296,621 300,463 0.37% Shares
Eversept Partners, LP $4,257,610 297,735 0.37% Shares
GOLDMAN SACHS GROUP INC $4,086,797 285,790 0.35% Shares
Rock Springs Capital Management LP $3,839,822 268,519 0.33% Shares
CITIGROUP INC $3,750,032 262,240 0.32% Shares
MYDA Advisors LLC $3,575,000 250,000 0.31% Shares
AXA Investment Managers S.A. $3,480,640 244,427 0.30% Shares
UBS Group AG $3,373,442 235,905 0.29% Shares
BNP PARIBAS ASSET MANAGEMENT Holding S.A. $3,342,639 233,751 0.29% Shares
Schonfeld Strategic Advisors LLC $3,285,853 229,780 0.28% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $3,038,750 212,500 0.26% Put option
Propel Bio Management, LLC $2,741,954 191,745 0.24% Shares
Qube Research & Technologies Ltd $2,704,159 189,102 0.23% Shares
Walleye Capital LLC $2,691,560 188,221 0.23% Shares
Susquehanna Portfolio Strategies, LLC $2,685,554 187,801 0.23% Shares
BlackRock, Inc. $2,649,890 185,307 0.23% Shares
CITADEL ADVISORS LLC $2,559,700 179,000 0.22% Put option
SCHRODER INVESTMENT MANAGEMENT GROUP $2,389,303 169,334 0.21% Shares
HighVista Strategies LLC $2,226,567 155,704 0.19% Shares
Granahan Investment Management, LLC $2,136,234 149,387 0.18% Shares
Swiss National Bank $2,034,890 142,300 0.17% Shares
STATE OF WISCONSIN INVESTMENT BOARD $1,998,711 139,770 0.17% Shares
PANAGORA ASSET MANAGEMENT INC $1,890,660 132,214 0.16% Shares
Corient Private Wealth LP $1,827,526 127,799 0.16% Shares
ESSEX INVESTMENT MANAGEMENT CO LLC $1,740,081 121,684 0.15% Shares
BOOTHBAY FUND MANAGEMENT, LLC $1,548,690 108,300 0.13% Call option
BOOTHBAY FUND MANAGEMENT, LLC $1,548,690 108,300 0.13% Put option
DIADEMA PARTNERS LP $1,520,090 106,300 0.13% Call option
SILVERBACK ASSET MANAGEMENT LLC $1,430,000 100,000 0.12% Call option
Squarepoint Ops LLC $1,401,429 98,002 0.12% Shares
RHUMBLINE ADVISERS $1,393,341 97,437 0.12% Shares
CITADEL ADVISORS LLC $1,357,070 94,900 0.12% Call option
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $1,354,752 105,101 0.12% Shares
ALGERT GLOBAL LLC $1,129,557 78,990 0.10% Shares
Waverly Advisors, LLC $1,114,170 77,914 0.10% Shares
Cinctive Capital Management LP $1,037,923 72,582 0.09% Shares
Caption Management, LLC $1,036,750 72,500 0.09% Call option
WELLINGTON MANAGEMENT GROUP LLP $1,035,134 72,387 0.09% Shares
GOLDMAN SACHS GROUP INC $1,002,430 70,100 0.09% Call option
DEUTSCHE BANK AG\ $989,860 69,221 0.09% Shares
Bank of New York Mellon Corp $981,824 68,659 0.08% Shares
WOODSTOCK CORP $979,049 68,465 0.08% Shares
ALLIANCEBERNSTEIN L.P. $971,081 75,336 0.08% Shares
BANK OF AMERICA CORP /DE/ $930,186 65,048 0.08% Shares
Zurcher Kantonalbank (Zurich Cantonalbank) $865,708 60,539 0.07% Shares
FOX RUN MANAGEMENT, L.L.C. $836,950 58,528 0.07% Shares
Y-Intercept (Hong Kong) Ltd $732,017 51,190 0.06% Shares
SILVERBACK ASSET MANAGEMENT LLC $715,000 50,000 0.06% Shares
JANE STREET GROUP, LLC $715,000 50,000 0.06% Call option
Erste Asset Management GmbH $705,500 50,000 0.06% Shares
VANGUARD ASSET MANAGEMENT, Ltd $702,545 49,129 0.06% Shares
Point72 Asset Management, L.P. $694,608 48,574 0.06% Shares
SBI Okasan Asset Management Co.Ltd. $644,827 45,700 0.06% Shares
MetLife Investment Management, LLC $621,607 43,469 0.05% Shares
JANE STREET GROUP, LLC $597,954 41,815 0.05% Shares
SCOTIA CAPITAL INC. $597,039 41,751 0.05% Shares

Company insiders 25 insiders · 12 officers · 16 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Jay S. Duker President and CEO July 10, 2026 M 9,594 0 0 $0
Nancy Lurker President & CEO Oct. 12, 2018 A 211,700 0 0 $0
Paul Ashton President & CEO March 18, 2016 M 450,741 0 0 $0
David Price Chief Financial Officer Aug. 1, 2018 A 0 0 $0
Michael Soja VP Finance, CFO & Treasurer Sept. 10, 2008 A 0 0 $0
Ramiro Ribeiro Chief Medical Officer June 30, 2026 M 0 0 2 $-73,174
Leonard S Ross Vice President of Finance and Chief Accounting Officer Dec. 22, 2018 M 76,187 0 0 $0
Dario A. Paggiarino Chief Medical Officer Oct. 12, 2018 F 29,600 0 0 $0
Leonard M Blum Executive VP and General Manager, US May 14, 2018 A 0 0 $0
Debora Jorn EVP, Corp. & Comm'l Dev. June 27, 2017 A 0 0 $0
Lori Freedman VP Corporate Affairs, General Counsel and Secretary July 21, 2016 A 96,423 0 0 $0
Aaron Finlay Secretary Oct. 18, 2007 A 0 0 $0
Karen L. Zaderej Director Aug. 18, 2026 P 49,100 1 0 $52,258
Wendy F Dicicco Director Jan. 2, 2026 A 0 0 $0
ANDO GORAN Director Jan. 2, 2026 A 0 0 $0
Fred Hassan Director Jan. 2, 2026 A 0 0 $0
Michael W Rogers Director Nov. 15, 2018 M 112,500 0 0 $0
John B. Landis Director Oct. 25, 2018 A 0 0 $0
David J Mazzo Director Sept. 6, 2018 A 138,000 0 0 $0
Douglas Evan Godshall Director June 27, 2018 M 12,500 0 0 $0
James J Barry Director May 7, 2018 M 12,500 0 0 $0
Kristine Peterson Director Dec. 15, 2017 A 0 0 $0
SAVAS PETER G Director Dec. 3, 2015 A 0 0 $0
Paul Hopper Director Dec. 18, 2013 A 10,000 0 0 $0
Katherine Woodthorpe Director Nov. 27, 2007 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 5 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
EW Healthcare Partners L.P., EW Healthcare Partners-A L.P., Essex Woodlands Fund IX-GP, L.P., Essex Woodlands IX, LLC, Martin P. Sutter, R. Scott Barry, Ronald Eastman, Petri Vainio, Steve Wiggins ×4 filings Dec. 8, 2023 Initial filing SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Aug. 30, 2023 Initial filing SEC
Ocumension Therapeutics Jan. 22, 2021 Initial filing SEC
IRS Identification Nos. of above persons (entities only) Pfizer Inc. ×2 filings May 26, 2017 Initial filing SEC
Pfizer Inc. July 17, 2007 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 42 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PILL · Direxion Shares ETF Trust 1.18% 11,564 NS April 30, 2026 N-PORT
BBC · ETFis Series Trust I 0.61% 17,260 NS April 30, 2026 N-PORT
FSCC · Federated Hermes ETF Trust 0.12% 25,180 NS May 31, 2026 N-PORT
NUSC · Nushares ETF Trust 0.08% 78,250 NS April 30, 2026 N-PORT
BIB · ProShares Trust 0.06% 3,062 NS May 31, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.04% 25,575 NS May 31, 2026 N-PORT
RSSL · Global X Funds 0.03% 33,518 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.03% 3,648 NS May 31, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.02% 378,469 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.02% 34,174 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.02% 2,853 NS May 31, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.01% 152,391 NS April 30, 2026 N-PORT
URTY · ProShares Trust 0.01% 2,885 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.01% 2,895 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 72 NS May 31, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.00% 28,026 NS May 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 3,564 NS April 30, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 46,188 NS May 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 10,667 NS April 30, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 41,879 NS April 30, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 13,282 NS April 30, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTI · VANGUARD INDEX FUNDS July 15, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND July 30, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
ITOT · iShares Trust July 22, 2026 Daily
IWV · iShares Trust Aug. 18, 2026 Daily
IWN · iShares Trust Aug. 17, 2026 Daily
IWO · iShares Trust Aug. 18, 2026 Daily
IWM · iShares Trust Aug. 18, 2026 Daily
IWC · iShares Trust Aug. 18, 2026 Daily
IHE · iShares Trust Aug. 18, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust July 13, 2026 Daily
VHT · VANGUARD WORLD FUND July 20, 2026 Daily
ISCB · iShares Trust July 20, 2026 Daily
ISCV · iShares Trust July 20, 2026 Daily
WSML · iShares Trust July 20, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … July 20, 2026 Daily
QQQS · Invesco Exchange-Traded Fund Trust … Aug. 5, 2026 Daily