Invesco Exchange-Traded Fund Trust II (IBBQ)
Management Company · XNAS · Series S000072469 · View on SEC EDGAR ↗
$36.29
As of Aug. 21, 2026
▲ +0.49 (+1.37%)
1-day change
$23.25 – $36.84
52-week range
+0.18%
Premium / Discount
NAV as of Aug. 20, 2026
Net flows (30d): +$7.7M Estimated from creation/redemption of shares outstanding
- Net assets
- $67.4M
- Holdings
- 261
- As of
- May 31, 2026
- Top 10 holdings weight
- 56.58%
- Effective number of positions
- 20.2
- Positions above 1%
- 27
On this page
- Price chart The fund's market price over time, with technical overlays.
- Performance Total return, volatility, drawdown and other risk metrics.
- Fund flows Money flowing in and out of the fund each month, from N-PORT filings.
- Holdings Every position the fund currently holds, with weights.
- Sector breakdown How the fund's holdings split across market sectors.
- Recent changes Positions the fund added, trimmed or exited most recently.
- Institutional owners 13F institutions that report holding this ETF.
- Similar funds Other funds with overlapping holdings or comparable size.
IBBQ Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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Performance as of Aug. 20, 2026
| Period | Price return | Total return |
|---|---|---|
| 1M | ▲ +21.11% | — |
| 3M | ▲ +21.11% | — |
| 6M | ▲ +20.40% | — |
| YTD | ▲ +26.07% | — |
| 1Y | ▲ +52.76% | — |
| 3Y | — | — |
| 5Y | — | — |
| Max since Feb. 27, 2024 | ▲ +55.79% | — |
- Volatility 1Y
- 26.86%
- Volatility 3Y
- —
- Max drawdown 3Y
- —
- Beta 3Y
- —
- Sharpe 1Y*
- 2.84
Total return is shown once dividend history for this fund has been collected — price return alone would duplicate it misleadingly. Returns are not benchmarked against an index. * Sharpe ratio is computed with a 0% risk-free rate.
Fund flows (SEC-reported)
- Last month (May 2026)
- +$0
- Quarter ending May 2026
- -$7.6M
- Trailing 12 months
- +$15.2M
Jun 2025 – May 2026
Based on the fund's own SEC Form N-PORT monthly flow disclosures (Item C.9 "Flow Information") — sales minus redemptions, reinvested distributions excluded. This is a different, independent metric from the "Net flows" estimate above (which is derived from daily shares-outstanding changes). SEC N-PORT filing lag is up to ~60 days; the most recent month/quarter may not yet be fully reflected.
Full composition 261 holdings
| Name | CUSIP | Value | % | Balance | Category | Country |
|---|---|---|---|---|---|---|
| Spyre Therapeutics, Inc. | 00773J202 | $309K | 0.46 | 4,207 | EC | US |
| Cogent Biosciences, Inc. | 19240Q201 | $304K | 0.45 | 8,702 | EC | US |
| CRISPR Therapeutics AG | H17182108 | $289K | 0.43 | 5,136 | EC | CH |
| CG Oncology, Inc. | 156944100 | $282K | 0.42 | 4,527 | EC | US |
| Scholar Rock Holding Corp. | 80706P103 | $269K | 0.40 | 5,458 | EC | US |
| Centessa Pharmaceuticals PLC | 152309100 | $255K | 0.38 | 6,401 | EC | GB |
| Caris Life Sciences, Inc. | 142152107 | $252K | 0.37 | 15,091 | EC | US |
| Ligand Pharmaceuticals Inc. | 53220K504 | $248K | 0.37 | 1,069 | EC | US |
| Xenon Pharmaceuticals Inc. | 98420N105 | $244K | 0.36 | 4,455 | EC | CA |
| Indivior Pharmaceuticals, Inc. | 45579U109 | $241K | 0.36 | 6,697 | EC | US |
| Apogee Therapeutics, Inc. | 03770N101 | $241K | 0.36 | 2,933 | EC | US |
| Travere Therapeutics, Inc. | 89422G107 | $233K | 0.35 | 4,947 | EC | US |
| Amneal Pharmaceuticals, Inc. | 03168L105 | $222K | 0.33 | 16,863 | EC | US |
| Twist Bioscience Corp. | 90184D100 | $220K | 0.33 | 3,287 | EC | US |
| Erasca, Inc. | 29479A108 | $213K | 0.32 | 16,597 | EC | US |
| NewAmsterdam Pharma Co. N.V. | N62509109 | $208K | 0.31 | 6,171 | EC | NL |
| Crinetics Pharmaceuticals, Inc. | 22663K107 | $200K | 0.30 | 5,613 | EC | US |
| Acadia Pharmaceuticals Inc. | 004225108 | $198K | 0.29 | 9,144 | EC | US |
| Veracyte, Inc. | 92337F107 | $197K | 0.29 | 4,260 | EC | US |
| Edgewise Therapeutics, Inc. | 28036F105 | $196K | 0.29 | 5,751 | EC | US |
| Beam Therapeutics Inc. | 07373V105 | $180K | 0.27 | 5,461 | EC | US |
| Denali Therapeutics Inc. | 24823R105 | $179K | 0.27 | 8,502 | EC | US |
| 10x Genomics, Inc. | 88025U109 | $179K | 0.27 | 6,309 | EC | US |
| Dyne Therapeutics, Inc. | 26818M108 | $171K | 0.25 | 8,827 | EC | US |
| Structure Therapeutics Inc. | 86366E106 | $164K | 0.24 | 4,176 | EC | KY |
| Tango Therapeutics Inc. | 87583X109 | $159K | 0.24 | 7,220 | EC | US |
| Oruka Therapeutics, Inc. | 687604108 | $152K | 0.23 | 2,595 | EC | US |
| GRAIL, Inc. | 384747101 | $150K | 0.22 | 2,094 | EC | US |
| Alumis Inc. | 022307102 | $146K | 0.22 | 6,778 | EC | US |
| Arcutis Biotherapeutics, Inc. | 03969K108 | $143K | 0.21 | 6,650 | EC | US |
| Disc Medicine, Inc. | 254604101 | $142K | 0.21 | 2,046 | EC | US |
| Supernus Pharmaceuticals, Inc. | 868459108 | $142K | 0.21 | 3,074 | EC | US |
| IDEAYA Biosciences, Inc. | 45166A102 | $139K | 0.21 | 4,708 | EC | US |
| Vera Therapeutics, Inc. | 92337R101 | $136K | 0.20 | 3,825 | EC | US |
| Tarsus Pharmaceuticals, Inc. | 87650L103 | $136K | 0.20 | 2,282 | EC | US |
| Relay Therapeutics, Inc. | 75943R102 | $135K | 0.20 | 9,582 | EC | US |
| Mineralys Therapeutics, Inc. | 603170101 | $134K | 0.20 | 4,243 | EC | US |
| Definium Therapeutics, Inc. | 24477V105 | $129K | 0.19 | 5,345 | EC | CA |
| Enliven Therapeutics, Inc. | 29337E102 | $126K | 0.19 | 3,182 | EC | US |
| Adaptive Biotechnologies Corp. | 00650F109 | $125K | 0.19 | 8,255 | EC | US |
| Ultragenyx Pharmaceutical Inc. | 90400D108 | $124K | 0.18 | 5,180 | EC | US |
| Legend Biotech Corp. | 52490G102 | $123K | 0.18 | 4,525 | EC | KY |
| Kodiak Sciences Inc. | 50015M109 | $120K | 0.18 | 3,273 | EC | US |
| BioCryst Pharmaceuticals, Inc. | 09058V103 | $120K | 0.18 | 13,446 | EC | US |
| Kiniksa Pharmaceuticals International, PLC | G52694109 | $119K | 0.18 | 2,461 | EC | GB |
| Aurinia Pharmaceuticals Inc. | 05156V102 | $109K | 0.16 | 7,129 | EC | CA |
| Ocular Therapeutix, Inc. | 67576A100 | $105K | 0.16 | 11,671 | EC | US |
| Pharvaris N.V. | N69605108 | $104K | 0.15 | 3,443 | EC | NL |
| NovoCure Ltd. | G6674U108 | $103K | 0.15 | 6,072 | EC | JE |
| Sionna Therapeutics, Inc. | 829401108 | $102K | 0.15 | 2,393 | EC | US |
Page 2
of 6
Sector breakdown
Healthcare
82.4%
Other/Unmapped
17.6%
Daily changes (30d)
| Date | Type | Ticker | Change |
|---|---|---|---|
| Aug. 20, 2026 | Trimmed |
2200963D — OmniAb Inc
68218J202
|
Units/share: 0.00005187 → 0.00004883 (-5.9%) |
| Aug. 20, 2026 | Trimmed |
2200964D — OmniAb Inc
68218J301
|
Units/share: 0.00005187 → 0.00004883 (-5.9%) |
| Aug. 20, 2026 | Trimmed |
2324462D — Cartesian Therapeutics Inc
816212112
|
Units/share: 0.001093 → 0.001029 (-5.9%) |
| Aug. 20, 2026 | Trimmed |
2600057D — Novo Nordisk A/S
009CVR108
|
Units/share: 0.001574 → 0.001482 (-5.9%) |
| Aug. 20, 2026 | Trimmed |
2645588D — Eli Lilly & Co
152CVR015
|
Units/share: 0.002632 → 0.002478 (-5.9%) |
| Aug. 20, 2026 | Trimmed |
2673120D — Esperion Therapeutics Inc
296CVR020
|
Units/share: 0.005488 → 0.005166 (-5.9%) |
| Aug. 20, 2026 | Trimmed |
ABVX — Abivax SA
00370M103
|
Units/share: 0.001331 → 0.001328 (-0.2%) |
| Aug. 20, 2026 | Increased |
AGIO — Agios Pharmaceuticals Inc
00847X104
|
Units/share: 0.001367 → 0.001369 (0.1%) |
| Aug. 20, 2026 | Trimmed |
AGPXX — Invesco Government & Agency Portfolio
825252885
|
Units/share: 0.01535 → 0.01502 (-2.2%) |
| Aug. 20, 2026 | Trimmed |
ALMS — Alumis Inc
022307102
|
Units/share: 0.002834 → 0.002831 (-0.1%) |
| Aug. 20, 2026 | Increased |
ALNY — Alnylam Pharmaceuticals Inc
02043Q107
|
Units/share: 0.003066 → 0.003069 (0.1%) |
| Aug. 20, 2026 | Increased |
AMLX — Amylyx Pharmaceuticals Inc
03237H101
|
Units/share: 0.002553 → 0.002558 (0.2%) |
| Aug. 20, 2026 | Trimmed |
AMPH — Amphastar Pharmaceuticals Inc
03209R103
|
Units/share: 0.001013 → 0.001011 (-0.1%) |
| Aug. 20, 2026 | Increased |
ANAB — AnaptysBio Inc
032724106
|
Units/share: 0.0006692 → 0.0006715 (0.3%) |
| Aug. 20, 2026 | Trimmed |
ANIP — ANI Pharmaceuticals Inc
00182C103
|
Units/share: 0.0005215 → 0.0005199 (-0.3%) |
| Aug. 20, 2026 | Trimmed |
APGE — Apogee Therapeutics Inc
03770N101
|
Units/share: 0.001422 → 0.00142 (-0.1%) |
| Aug. 20, 2026 | Increased |
AQST — Aquestive Therapeutics Inc
03843E104
|
Units/share: 0.002852 → 0.002857 (0.2%) |
| Aug. 20, 2026 | Trimmed |
ARCT — Arcturus Therapeutics Holdings Inc
03969T109
|
Units/share: 0.0006432 → 0.0006406 (-0.4%) |
| Aug. 20, 2026 | Trimmed |
ARGX — Argenx SE
04016X101
|
Units/share: 0.0006329 → 0.0006305 (-0.4%) |
| Aug. 20, 2026 | Increased |
ARVN — Arvinas Inc
04335A105
|
Units/share: 0.001467 → 0.00147 (0.2%) |
| Aug. 20, 2026 | Trimmed |
ARWR — Arrowhead Pharmaceuticals Inc
04280A100
|
Units/share: 0.003235 → 0.003231 (-0.1%) |
| Aug. 20, 2026 | Increased |
AUPH — Aurinia Pharmaceuticals Inc
05156V102
|
Units/share: 0.002953 → 0.002957 (0.2%) |
| Aug. 20, 2026 | Increased |
AURA — Aura Biosciences Inc
05153U107
|
Units/share: 0.002374 → 0.002377 (0.1%) |
| Aug. 20, 2026 | Increased |
AVBP — ArriVent Biopharma Inc
04272N102
|
Units/share: 0.001071 → 0.001072 (0.2%) |
| Aug. 20, 2026 | Increased |
AXSM — Axsome Therapeutics Inc
05464T104
|
Units/share: 0.001182 → 0.001184 (0.2%) |
| Aug. 20, 2026 | Increased |
BCYC — Bicycle Therapeutics PLC
088786108
|
Units/share: 0.001062 → 0.001064 (0.2%) |
| Aug. 20, 2026 | Increased |
BEAM — Beam Therapeutics Inc
07373V105
|
Units/share: 0.002362 → 0.002366 (0.2%) |
| Aug. 20, 2026 | Trimmed |
BIOA — BioAge Labs Inc
09077V100
|
Units/share: 0.001021 → 0.001019 (-0.2%) |
| Aug. 20, 2026 | Increased |
BNTX — BioNTech SE
09075V102
|
Units/share: 0.002668 → 0.002671 (0.1%) |
| Aug. 20, 2026 | Increased |
CADL — Candel Therapeutics Inc
137404109
|
Units/share: 0.001683 → 0.001684 (0.1%) |
| Aug. 20, 2026 | Increased |
CDXS — Codexis Inc
192005106
|
Units/share: 0.002067 → 0.00207 (0.2%) |
| Aug. 20, 2026 | Trimmed |
CGON — CG oncology Inc
156944100
|
Units/share: 0.002026 → 0.002023 (-0.1%) |
| Aug. 20, 2026 | Increased |
CMPS — Compass Pathways Plc
20451W101
|
Units/share: 0.003056 → 0.003061 (0.1%) |
| Aug. 20, 2026 | Trimmed |
COLL — Collegium Pharmaceutical Inc
19459J104
|
Units/share: 0.0007435 → 0.0007402 (-0.4%) |
| Aug. 20, 2026 | Increased |
CRBU — Caribou Biosciences Inc
142038108
|
Units/share: 0.002255 → 0.00226 (0.2%) |
| Aug. 20, 2026 | Trimmed |
CRVS — Corvus Pharmaceuticals Inc
221015100
|
Units/share: 0.001931 → 0.001928 (-0.2%) |
| Aug. 20, 2026 | Increased |
CTNM — Contineum Therapeutics Inc
21217B100
|
Units/share: 0.0007535 → 0.0007562 (0.4%) |
| Aug. 20, 2026 | Trimmed |
DNLI — Denali Therapeutics Inc
24823R105
|
Units/share: 0.003645 → 0.00364 (-0.1%) |
| Aug. 20, 2026 | Trimmed |
DSGN — Design Therapeutics Inc
25056L103
|
Units/share: 0.001434 → 0.001431 (-0.2%) |
| Aug. 20, 2026 | Increased |
ENTA — Enanta Pharmaceuticals Inc
29251M106
|
Units/share: 0.0006624 → 0.0006652 (0.4%) |
| Aug. 20, 2026 | Trimmed |
ETON — Eton Pharmaceuticals Inc
29772L108
|
Units/share: 0.0006283 → 0.0006262 (-0.3%) |
| Aug. 20, 2026 | Increased |
EWTX — Edgewise Therapeutics Inc
28036F105
|
Units/share: 0.002471 → 0.002473 (0.1%) |
| Aug. 20, 2026 | Trimmed |
EYPT — EyePoint Inc
30233G209
|
Units/share: 0.001925 → 0.001923 (-0.1%) |
| Aug. 20, 2026 | Trimmed |
FHTX — Foghorn Therapeutics Inc
344174107
|
Units/share: 0.001332 → 0.00133 (-0.1%) |
| Aug. 20, 2026 | Increased |
FTRE — Fortrea Holdings Inc
34965K107
|
Units/share: 0.002172 → 0.002175 (0.1%) |
| Aug. 20, 2026 | Trimmed |
GH — Guardant Health Inc
40131M109
|
Units/share: 0.003045 → 0.003041 (-0.1%) |
| Aug. 20, 2026 | Increased |
GHRS — GH Research PLC
G3855L106
|
Units/share: 0.001575 → 0.001578 (0.2%) |
| Aug. 20, 2026 | Trimmed |
GLUE — Monte Rosa Therapeutics Inc
61225M102
|
Units/share: 0.00194 → 0.001936 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
GMAB — Genmab A/S
372303206
|
Units/share: 0.001741 → 0.001738 (-0.1%) |
| Aug. 20, 2026 | Increased |
GRAL — GRAIL Inc
384747101
|
Units/share: 0.0009853 → 0.0009867 (0.1%) |
| Aug. 20, 2026 | Trimmed |
HRMY — Harmony Biosciences Holdings Inc
413197104
|
Units/share: 0.001329 → 0.001327 (-0.2%) |
| Aug. 20, 2026 | Increased |
HROW — Harrow Inc
415858109
|
Units/share: 0.000857 → 0.0008602 (0.4%) |
| Aug. 20, 2026 | Trimmed |
IMCR — Immunocore Holdings PLC
45258D105
|
Units/share: 0.001021 → 0.001019 (-0.2%) |
| Aug. 20, 2026 | Increased |
IMRX — Immuneering Corp
45254E107
|
Units/share: 0.001471 → 0.001474 (0.2%) |
| Aug. 20, 2026 | Trimmed |
INBX — Inhibrx Biosciences Inc
45720N103
|
Units/share: 0.0003353 → 0.0003332 (-0.6%) |
| Aug. 20, 2026 | Increased |
IRON — Disc Medicine Inc
254604101
|
Units/share: 0.000878 → 0.0008793 (0.1%) |
| Aug. 20, 2026 | Trimmed |
JAZZ — Jazz Pharmaceuticals PLC
G50871105
|
Units/share: 0.001439 → 0.001437 (-0.2%) |
| Aug. 20, 2026 | Increased |
KNSA — Kiniksa Pharmaceuticals International Plc
G52694109
|
Units/share: 0.001065 → 0.001067 (0.2%) |
| Aug. 20, 2026 | Trimmed |
KOD — Kodiak Sciences Inc
50015M109
|
Units/share: 0.001435 → 0.001433 (-0.1%) |
| Aug. 20, 2026 | Increased |
KROS — Keros Therapeutics Inc
492327101
|
Units/share: 0.0004539 → 0.0004566 (0.6%) |
| Aug. 20, 2026 | Increased |
KRYS — Krystal Biotech Inc
501147102
|
Units/share: 0.000678 → 0.0006793 (0.2%) |
| Aug. 20, 2026 | Trimmed |
KURA — Kura Oncology Inc
50127T109
|
Units/share: 0.002039 → 0.002035 (-0.2%) |
| Aug. 20, 2026 | Increased |
KYTX — Kyverna Therapeutics Inc
501976104
|
Units/share: 0.001382 → 0.001384 (0.1%) |
| Aug. 20, 2026 | Trimmed |
LEGN — Legend Biotech Corp
52490G102
|
Units/share: 0.001938 → 0.001934 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
LENZ — LENZ Therapeutics Inc
52635N103
|
Units/share: 0.0007121 → 0.0007109 (-0.2%) |
| Aug. 20, 2026 | Increased |
LFCR — Lifecore Biomedical Inc
514766104
|
Units/share: 0.0008544 → 0.0008578 (0.4%) |
| Aug. 20, 2026 | Increased |
LGND — Ligand Pharmaceuticals Inc
53220K504
|
Units/share: 0.0004618 → 0.0004641 (0.5%) |
| Aug. 20, 2026 | Trimmed |
LKFT — Lakefront Biotherapeutics NV
36315X101
|
Units/share: 0.0003432 → 0.0003406 (-0.7%) |
| Aug. 20, 2026 | Increased |
LRMR — Larimar Therapeutics Inc
517125100
|
Units/share: 0.002362 → 0.002366 (0.2%) |
| Aug. 20, 2026 | Trimmed |
LYEL — Lyell Immunopharma Inc
55083R203
|
Units/share: 0.0005287 → 0.0005266 (-0.4%) |
| Aug. 20, 2026 | Increased |
MAZE — Maze Therapeutics Inc
578784100
|
Units/share: 0.001271 → 0.001274 (0.2%) |
| Aug. 20, 2026 | Trimmed |
MDGL — Madrigal Pharmaceuticals Inc
558868105
|
Units/share: 0.0005287 → 0.0005266 (-0.4%) |
| Aug. 20, 2026 | Increased |
MEDP — Medpace Holdings Inc
58506Q109
|
Units/share: 0.0006577 → 0.0006602 (0.4%) |
| Aug. 20, 2026 | Trimmed |
MENS — Jyong Biotech Ltd
G83116106
|
Units/share: 0.001727 → 0.001725 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
MGTX — MeiraGTx Holdings plc
G59665102
|
Units/share: 0.002126 → 0.002124 (-0.1%) |
| Aug. 20, 2026 | Increased |
NBP — NovaBridge Biosciences
44975P103
|
Units/share: 0.002552 → 0.002557 (0.2%) |
| Aug. 20, 2026 | Increased |
NGNE — Neurogene Inc
64135M105
|
Units/share: 0.0003614 → 0.0003637 (0.6%) |
| Aug. 20, 2026 | Increased |
NRIX — Nurix Therapeutics Inc
67080M103
|
Units/share: 0.002374 → 0.002377 (0.1%) |
| Aug. 20, 2026 | Increased |
NVCR — Novocure Ltd
G6674U108
|
Units/share: 0.00266 → 0.002664 (0.1%) |
| Aug. 20, 2026 | Increased |
OBIO — Orchestra BioMed Holdings Inc
68572M106
|
Units/share: 0.001363 → 0.001366 (0.2%) |
| Aug. 20, 2026 | Increased |
OMER — Omeros Corp
682143102
|
Units/share: 0.001662 → 0.001666 (0.2%) |
| Aug. 20, 2026 | Increased |
ONC — BeOne Medicines Ltd
07725L102
|
Units/share: 0.0007595 → 0.0007625 (0.4%) |
| Aug. 20, 2026 | Increased |
ORKA — Oruka Therapeutics Inc
687604108
|
Units/share: 0.001385 → 0.001386 (0.1%) |
| Aug. 20, 2026 | Increased |
PAHC — Phibro Animal Health Corp
71742Q106
|
Units/share: 0.0004846 → 0.0004855 (0.2%) |
| Aug. 20, 2026 | Increased |
PBYI — Puma Biotechnology Inc
74587V107
|
Units/share: 0.001159 → 0.001162 (0.2%) |
| Aug. 20, 2026 | Increased |
PEPG — PepGen Inc
713317105
|
Units/share: 0.001573 → 0.001575 (0.2%) |
| Aug. 20, 2026 | Trimmed |
PHAT — Phathom Pharmaceuticals Inc
71722W107
|
Units/share: 0.001832 → 0.001829 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
PRAX — Praxis Precision Medicines Inc
74006W207
|
Units/share: 0.0006386 → 0.0006363 (-0.4%) |
| Aug. 20, 2026 | Trimmed |
PRME — Prime Medicine Inc
74168J101
|
Units/share: 0.004148 → 0.004143 (-0.1%) |
| Aug. 20, 2026 | Increased |
PTGX — Protagonist Therapeutics Inc
74366E102
|
Units/share: 0.001477 → 0.001479 (0.2%) |
| Aug. 20, 2026 | Trimmed |
PYXS — Pyxis Oncology Inc
747324101
|
Units/share: 0.001437 → 0.001435 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
QURE — uniQure NV
N90064101
|
Units/share: 0.001446 → 0.001443 (-0.2%) |
| Aug. 20, 2026 | Increased |
RANI — Rani Therapeutics Holdings Inc
753018100
|
Units/share: 0.002555 → 0.00256 (0.2%) |
| Aug. 20, 2026 | Increased |
RARE — Ultragenyx Pharmaceutical Inc
90400D108
|
Units/share: 0.002261 → 0.002265 (0.2%) |
| Aug. 20, 2026 | Increased |
REGN — Regeneron Pharmaceuticals Inc
75886F107
|
Units/share: 0.002366 → 0.002369 (0.1%) |
| Aug. 20, 2026 | Increased |
RGNX — REGENXBIO Inc
75901B107
|
Units/share: 0.001187 → 0.001188 (0.1%) |
| Aug. 20, 2026 | Trimmed |
RIGL — Rigel Pharmaceuticals Inc
766559702
|
Units/share: 0.0004241 → 0.0004223 (-0.4%) |
| Aug. 20, 2026 | Increased |
RYTM — Rhythm Pharmaceuticals Inc
76243J105
|
Units/share: 0.001575 → 0.001577 (0.2%) |
| Aug. 20, 2026 | Trimmed |
SEPN — Septerna Inc
81734D104
|
Units/share: 0.001034 → 0.001032 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
SIGA — SIGA Technologies Inc
826917106
|
Units/share: 0.001629 → 0.001627 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
SION — Sionna Therapeutics Inc
829401108
|
Units/share: 0.001035 → 0.001033 (-0.2%) |
| Aug. 20, 2026 | Increased |
SLDB — Solid Biosciences Inc
83422E204
|
Units/share: 0.002261 → 0.002264 (0.2%) |
| Aug. 20, 2026 | Increased |
SLN — Silence Therapeutics PLC
82686Q101
|
Units/share: 0.001069 → 0.001071 (0.2%) |
| Aug. 20, 2026 | Trimmed |
SNDX — Syndax Pharmaceuticals Inc
87164F105
|
Units/share: 0.002035 → 0.002031 (-0.2%) |
| Aug. 20, 2026 | Increased |
SRRK — Scholar Rock Holding Corp
80706P103
|
Units/share: 0.002752 → 0.002756 (0.2%) |
| Aug. 20, 2026 | Trimmed |
STOK — Stoke Therapeutics Inc
86150R107
|
Units/share: 0.00143 → 0.001427 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
SUPN — Supernus Pharmaceuticals Inc
868459108
|
Units/share: 0.001332 → 0.00133 (-0.1%) |
| Aug. 20, 2026 | Increased |
TARS — Tarsus Pharmaceuticals Inc
87650L103
|
Units/share: 0.0009879 → 0.0009891 (0.1%) |
| Aug. 20, 2026 | Increased |
TBPH — Theravance Biopharma Inc
G8807B106
|
Units/share: 0.001184 → 0.001186 (0.1%) |
| Aug. 20, 2026 | Trimmed |
TECX — Tectonic Therapeutic Inc
878972108
|
Units/share: 0.000432 → 0.0004301 (-0.4%) |
| Aug. 20, 2026 | Trimmed |
THRD — Third Harmonic Bio Inc
88427A107
|
Units/share: 0.000666 → 0.000627 (-5.9%) |
| Aug. 20, 2026 | Trimmed |
TKNO — Alpha Teknova Inc
02080L102
|
Units/share: 0.001218 → 0.001216 (-0.1%) |
| Aug. 20, 2026 | Increased |
TRDA — Entrada Therapeutics Inc
29384C108
|
Units/share: 0.0008827 → 0.0008844 (0.2%) |
| Aug. 20, 2026 | Increased |
TRVI — Trevi Therapeutics Inc
89532M101
|
Units/share: 0.00326 → 0.003264 (0.1%) |
| Aug. 20, 2026 | Trimmed |
TVTX — Travere Therapeutics Inc
89422G107
|
Units/share: 0.002135 → 0.002132 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
TWST — Twist Bioscience Corp
90184D100
|
Units/share: 0.00143 → 0.001427 (-0.2%) |
| Aug. 20, 2026 | Increased |
TYRA — Tyra Biosciences Inc
90240B106
|
Units/share: 0.001367 → 0.001369 (0.1%) |
| Aug. 20, 2026 | Trimmed |
UPB — Upstream Bio Inc
91678A107
|
Units/share: 0.001234 → 0.001232 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
URGN — UroGen Pharma Ltd
M96088105
|
Units/share: 0.001119 → 0.001117 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
USD — CASH & EQUIVALENTS
CASHUSD00
|
Units/share: 0.003576 → 0.003503 (-2.0%) |
| Aug. 20, 2026 | Increased |
UTHR — United Therapeutics Corp
91307C102
|
Units/share: 0.0009759 → 0.0009773 (0.1%) |
| Aug. 20, 2026 | Increased |
VCEL — Vericel Corp
92346J108
|
Units/share: 0.001173 → 0.001175 (0.2%) |
| Aug. 20, 2026 | Trimmed |
VCYT — Veracyte Inc
92337F107
|
Units/share: 0.001832 → 0.001829 (-0.2%) |
| Aug. 20, 2026 | Trimmed |
VERA — Vera Therapeutics Inc
92337R101
|
Units/share: 0.001646 → 0.001644 (-0.2%) |
| Aug. 20, 2026 | Increased |
VNDA — Vanda Pharmaceuticals Inc
921659108
|
Units/share: 0.001368 → 0.001371 (0.2%) |
| Aug. 20, 2026 | Trimmed |
VOR — Vor BioPharma Inc
929033207
|
Units/share: 0.001242 → 0.00124 (-0.2%) |
| Aug. 20, 2026 | Increased |
VYGR — Voyager Therapeutics Inc
92915B106
|
Units/share: 0.001374 → 0.001377 (0.2%) |
| Aug. 20, 2026 | Trimmed |
ZBIO — Zenas Biopharma Inc
98937L105
|
Units/share: 0.001448 → 0.001445 (-0.2%) |
| Aug. 20, 2026 | Increased |
ZLAB — Zai Lab Ltd
98887Q104
|
Units/share: 0.0007574 → 0.0007605 (0.4%) |
| Aug. 20, 2026 | Increased |
ZVRA — Zevra Therapeutics Inc
488445206
|
Units/share: 0.001359 → 0.001362 (0.2%) |
| Aug. 20, 2026 | Increased |
ZYME — Zymeworks Inc
98985Y108
|
Units/share: 0.001677 → 0.001679 (0.1%) |
| Aug. 20, 2026 | Trimmed |
— SECURITIES LENDING - BNYM
BNYMLEND
|
Units/share: 0.0000004149 → 0.0000003906 (-5.9%) |
| Aug. 14, 2026 | Trimmed |
2200963D — OmniAb Inc
68218J202
|
Units/share: 0.00005274 → 0.00005187 (-1.7%) |
| Aug. 14, 2026 | Trimmed |
2200964D — OmniAb Inc
68218J301
|
Units/share: 0.00005274 → 0.00005187 (-1.7%) |
| Aug. 14, 2026 | Trimmed |
2324462D — Cartesian Therapeutics Inc
816212112
|
Units/share: 0.001111 → 0.001093 (-1.7%) |
| Aug. 14, 2026 | Trimmed |
2600057D — Novo Nordisk A/S
009CVR108
|
Units/share: 0.001601 → 0.001574 (-1.7%) |
| Aug. 14, 2026 | Trimmed |
2645588D — Eli Lilly & Co
152CVR015
|
Units/share: 0.002677 → 0.002632 (-1.7%) |
| Aug. 14, 2026 | Trimmed |
2673120D — Esperion Therapeutics Inc
296CVR020
|
Units/share: 0.00558 → 0.005488 (-1.7%) |
| Aug. 14, 2026 | Increased |
AGIO — Agios Pharmaceuticals Inc
00847X104
|
Units/share: 0.001366 → 0.001367 (0.1%) |
| Aug. 14, 2026 | Trimmed |
AGPXX — Invesco Government & Agency Portfolio
825252885
|
Units/share: 0.01913 → 0.01535 (-19.8%) |
| Aug. 14, 2026 | Trimmed |
ARCT — Arcturus Therapeutics Holdings Inc
03969T109
|
Units/share: 0.0006439 → 0.0006432 (-0.1%) |
| Aug. 14, 2026 | Increased |
AVBP — ArriVent Biopharma Inc
04272N102
|
Units/share: 0.001069 → 0.001071 (0.1%) |
| Aug. 14, 2026 | Increased |
BCYC — Bicycle Therapeutics PLC
088786108
|
Units/share: 0.001061 → 0.001062 (0.2%) |
| Aug. 14, 2026 | Increased |
CTNM — Contineum Therapeutics Inc
21217B100
|
Units/share: 0.0007527 → 0.0007535 (0.1%) |
| Aug. 14, 2026 | Trimmed |
FHTX — Foghorn Therapeutics Inc
344174107
|
Units/share: 0.001334 → 0.001332 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
GMAB — Genmab A/S
372303206
|
Units/share: 0.001742 → 0.001741 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
INBX — Inhibrx Biosciences Inc
45720N103
|
Units/share: 0.0003359 → 0.0003353 (-0.2%) |
| Aug. 14, 2026 | Increased |
IRON — Disc Medicine Inc
254604101
|
Units/share: 0.0008771 → 0.000878 (0.1%) |
| Aug. 14, 2026 | Trimmed |
JAZZ — Jazz Pharmaceuticals PLC
G50871105
|
Units/share: 0.001441 → 0.001439 (-0.1%) |
| Aug. 14, 2026 | Increased |
KNSA — Kiniksa Pharmaceuticals International Plc
G52694109
|
Units/share: 0.001063 → 0.001065 (0.1%) |
| Aug. 14, 2026 | Trimmed |
KOD — Kodiak Sciences Inc
50015M109
|
Units/share: 0.001437 → 0.001435 (-0.1%) |
| Aug. 14, 2026 | Increased |
KROS — Keros Therapeutics Inc
492327101
|
Units/share: 0.0004532 → 0.0004539 (0.2%) |
| Aug. 14, 2026 | Increased |
KRYS — Krystal Biotech Inc
501147102
|
Units/share: 0.0006771 → 0.000678 (0.1%) |
| Aug. 14, 2026 | Increased |
LGND — Ligand Pharmaceuticals Inc
53220K504
|
Units/share: 0.0004612 → 0.0004618 (0.1%) |
| Aug. 14, 2026 | Trimmed |
LKFT — Lakefront Biotherapeutics NV
36315X101
|
Units/share: 0.0003439 → 0.0003432 (-0.2%) |
| Aug. 14, 2026 | Increased |
MEDP — Medpace Holdings Inc
58506Q109
|
Units/share: 0.000657 → 0.0006577 (0.1%) |
| Aug. 14, 2026 | Increased |
NGNE — Neurogene Inc
64135M105
|
Units/share: 0.0003608 → 0.0003614 (0.2%) |
| Aug. 14, 2026 | Increased |
OBIO — Orchestra BioMed Holdings Inc
68572M106
|
Units/share: 0.001362 → 0.001363 (0.1%) |
| Aug. 14, 2026 | Increased |
PAHC — Phibro Animal Health Corp
71742Q106
|
Units/share: 0.000484 → 0.0004846 (0.1%) |
| Aug. 14, 2026 | Increased |
PBYI — Puma Biotechnology Inc
74587V107
|
Units/share: 0.001158 → 0.001159 (0.2%) |
| Aug. 14, 2026 | Trimmed |
PRAX — Praxis Precision Medicines Inc
74006W207
|
Units/share: 0.0006392 → 0.0006386 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
PYXS — Pyxis Oncology Inc
747324101
|
Units/share: 0.001439 → 0.001437 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
QURE — uniQure NV
N90064101
|
Units/share: 0.001448 → 0.001446 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
SEPN — Septerna Inc
81734D104
|
Units/share: 0.001035 → 0.001034 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
SION — Sionna Therapeutics Inc
829401108
|
Units/share: 0.001037 → 0.001035 (-0.1%) |
| Aug. 14, 2026 | Increased |
SLN — Silence Therapeutics PLC
82686Q101
|
Units/share: 0.001068 → 0.001069 (0.1%) |
| Aug. 14, 2026 | Trimmed |
SUPN — Supernus Pharmaceuticals Inc
868459108
|
Units/share: 0.001333 → 0.001332 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
TECX — Tectonic Therapeutic Inc
878972108
|
Units/share: 0.0004325 → 0.000432 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
THRD — Third Harmonic Bio Inc
88427A107
|
Units/share: 0.0006772 → 0.000666 (-1.7%) |
| Aug. 14, 2026 | Increased |
TYRA — Tyra Biosciences Inc
90240B106
|
Units/share: 0.001366 → 0.001367 (0.1%) |
| Aug. 14, 2026 | Trimmed |
UPB — Upstream Bio Inc
91678A107
|
Units/share: 0.001236 → 0.001234 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
USD — CASH & EQUIVALENTS
CASHUSD00
|
Units/share: 0.003636 → 0.003576 (-1.7%) |
| Aug. 14, 2026 | Increased |
UTHR — United Therapeutics Corp
91307C102
|
Units/share: 0.0009749 → 0.0009759 (0.1%) |
| Aug. 14, 2026 | Trimmed |
VERA — Vera Therapeutics Inc
92337R101
|
Units/share: 0.001648 → 0.001646 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
VOR — Vor BioPharma Inc
929033207
|
Units/share: 0.001244 → 0.001242 (-0.1%) |
| Aug. 14, 2026 | Trimmed |
ZBIO — Zenas Biopharma Inc
98937L105
|
Units/share: 0.00145 → 0.001448 (-0.1%) |
| Aug. 14, 2026 | Increased |
ZVRA — Zevra Therapeutics Inc
488445206
|
Units/share: 0.001358 → 0.001359 (0.1%) |
| Aug. 14, 2026 | Trimmed |
— SECURITIES LENDING - BNYM
BNYMLEND
|
Units/share: 0.0000004219 → 0.0000004149 (-1.7%) |
| Aug. 10, 2026 | Exited |
9666679D
Y95308105
|
Position exited — was 0.004418 units/share |
| Aug. 10, 2026 | New |
WVE — Wave Life Sciences Inc
94352A104
|
New position — 0.004418 units/share |
| Aug. 4, 2026 | Trimmed |
2200963D — OmniAb Inc
68218J202
|
Units/share: 0.00005342 → 0.00005274 (-1.3%) |
| Aug. 4, 2026 | Trimmed |
2200964D — OmniAb Inc
68218J301
|
Units/share: 0.00005342 → 0.00005274 (-1.3%) |
| Aug. 4, 2026 | Trimmed |
2324462D — Cartesian Therapeutics Inc
816212112
|
Units/share: 0.001125 → 0.001111 (-1.3%) |
| Aug. 4, 2026 | Trimmed |
2600057D — Novo Nordisk A/S
009CVR108
|
Units/share: 0.001621 → 0.001601 (-1.3%) |
| Aug. 4, 2026 | Trimmed |
2645588D — Eli Lilly & Co
152CVR015
|
Units/share: 0.002711 → 0.002677 (-1.3%) |
| Aug. 4, 2026 | Trimmed |
2673120D — Esperion Therapeutics Inc
296CVR020
|
Units/share: 0.005652 → 0.00558 (-1.3%) |
| Aug. 4, 2026 | Trimmed |
AGPXX — Invesco Government & Agency Portfolio
825252885
|
Units/share: 0.01924 → 0.01913 (-0.6%) |
| Aug. 4, 2026 | Increased |
ANAB — AnaptysBio Inc
032724106
|
Units/share: 0.0006684 → 0.0006692 (0.1%) |
| Aug. 4, 2026 | Trimmed |
ANIP — ANI Pharmaceuticals Inc
00182C103
|
Units/share: 0.0005221 → 0.0005215 (-0.1%) |
| Aug. 4, 2026 | Trimmed |
ARCT — Arcturus Therapeutics Holdings Inc
03969T109
|
Units/share: 0.000645 → 0.0006439 (-0.2%) |
| Aug. 4, 2026 | Trimmed |
ARGX — Argenx SE
04016X101
|
Units/share: 0.0006338 → 0.0006329 (-0.1%) |
| Aug. 4, 2026 | Trimmed |
COLL — Collegium Pharmaceutical Inc
19459J104
|
Units/share: 0.0007446 → 0.0007435 (-0.2%) |
| Aug. 4, 2026 | Increased |
CTNM — Contineum Therapeutics Inc
21217B100
|
Units/share: 0.0007515 → 0.0007527 (0.2%) |
| Aug. 4, 2026 | Increased |
ENTA — Enanta Pharmaceuticals Inc
29251M106
|
Units/share: 0.0006615 → 0.0006624 (0.1%) |
| Aug. 4, 2026 | Trimmed |
ETON — Eton Pharmaceuticals Inc
29772L108
|
Units/share: 0.000629 → 0.0006283 (-0.1%) |
| Aug. 4, 2026 | Increased |
HROW — Harrow Inc
415858109
|
Units/share: 0.0008558 → 0.000857 (0.1%) |
| Aug. 4, 2026 | Trimmed |
INBX — Inhibrx Biosciences Inc
45720N103
|
Units/share: 0.0003363 → 0.0003359 (-0.1%) |
| Aug. 4, 2026 | Increased |
KROS — Keros Therapeutics Inc
492327101
|
Units/share: 0.0004526 → 0.0004532 (0.1%) |
| Aug. 4, 2026 | Increased |
LFCR — Lifecore Biomedical Inc
514766104
|
Units/share: 0.0008532 → 0.0008544 (0.1%) |
| Aug. 4, 2026 | Increased |
LGND — Ligand Pharmaceuticals Inc
53220K504
|
Units/share: 0.0004607 → 0.0004612 (0.1%) |
Showing latest 200 of 499 changes
Institutional owners (13F) 37 filers
Institutions that report holding this ETF in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | % of tracked 13F | Shares | Type | As of |
|---|---|---|---|---|---|
| RAYMOND JAMES FINANCIAL INC | $2,557,596 | 15.82% | 78,310 | Shares | June 30, 2026 |
| WMS Group LLC | $1,930,794 | 11.94% | 59,118 | Shares | June 30, 2026 |
| TWO SIGMA INVESTMENTS, LP | $1,678,724 | 10.38% | 51,400 | Shares | June 30, 2026 |
| COMMONWEALTH EQUITY SERVICES, LLC | $1,631,404 | 10.09% | 49,951 | Shares | June 30, 2026 |
| Independent Advisor Alliance | $969,232 | 5.99% | 29,676 | Shares | June 30, 2026 |
| KNIGHTSBRIDGE ASSET MANAGEMENT, LLC | $956,938 | 5.92% | 29,300 | Shares | June 30, 2026 |
| Advisory Services Network, LLC | $710,638 | 4.39% | 21,759 | Shares | June 30, 2026 |
| Churchill Financial Advisors, LLC | $663,847 | 4.11% | 20,326 | Shares | June 30, 2026 |
| Orion Porfolio Solutions, LLC | $646,333 | 4.00% | 19,790 | Shares | June 30, 2026 |
| Clearstead Advisors, LLC | $634,959 | 3.93% | 19,441 | Shares | June 30, 2026 |
| LPL Financial LLC | $521,254 | 3.22% | 15,960 | Shares | June 30, 2026 |
| Tower Research Capital LLC (TRC) | $496,236 | 3.07% | 15,194 | Shares | June 30, 2026 |
| Concurrent Investment Advisors, LLC | $463,849 | 2.87% | 14,202 | Shares | June 30, 2026 |
| Clarius Group, LLC | $407,512 | 2.52% | 19,231 | Shares | March 31, 2025 |
| Beckerman Institutional, LLC | $374,138 | 2.31% | 11,456 | Shares | June 30, 2026 |
| OSAIC HOLDINGS, INC. | $340,685 | 2.11% | 10,431 | Shares | June 30, 2026 |
| CreativeOne Wealth, LLC | $289,470 | 1.79% | 8,863 | Shares | June 30, 2026 |
| Ignite Planners, LLC | $260,267 | 1.61% | 7,954 | Shares | June 30, 2026 |
| Breakwater Capital Group | $230,678 | 1.43% | 7,063 | Shares | June 30, 2026 |
| Lauer Wealth, LLC | $201,252 | 1.24% | 6,200 | Shares | June 30, 2026 |
| ROYAL BANK OF CANADA | $43,000 | 0.27% | 1,306 | Shares | June 30, 2026 |
| ORG Partners LLC | $30,298 | 0.19% | 1,067 | Shares | Dec. 31, 2025 |
| Signature Equity Partners, LLC | $21,345 | 0.13% | 654 | Shares | June 30, 2026 |
| Princeton Global Asset Management LLC | $19,617 | 0.12% | 601 | Shares | June 30, 2026 |
| MORGAN STANLEY | $17,963 | 0.11% | 550 | Shares | June 30, 2026 |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | $16,330 | 0.10% | 500 | Shares | June 30, 2026 |
| WR Wealth Planners, LLC | $14,741 | 0.09% | 685 | Shares | Dec. 31, 2024 |
| FMR LLC | $8,590 | 0.05% | 263 | Shares | June 30, 2026 |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | $8,197 | 0.05% | 251 | Shares | June 30, 2026 |
| PRIVATE TRUST CO NA | $7,414 | 0.05% | 227 | Shares | June 30, 2026 |
| HARBOUR INVESTMENTS, INC. | $5,467 | 0.03% | 167 | Shares | June 30, 2026 |
| Strengthening Families & Communities, LLC | $3,218 | 0.02% | 99 | Shares | June 30, 2026 |
| WELLS FARGO & COMPANY/MN | $2,776 | 0.02% | 85 | Shares | June 30, 2026 |
| Institute for Wealth Management, LLC. | $2,515 | 0.02% | 77 | Shares | June 30, 2026 |
| AE Wealth Management LLC | $2,188 | 0.01% | 67 | Shares | June 30, 2026 |
| Meramec Financial Planners, LLC | $815 | 0.01% | 25 | Shares | June 30, 2026 |
| Farmers & Merchants Trust Co of Chambersburg PA | $7 | 0.00% | 200 | Shares | June 30, 2026 |
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