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Cynthia Smith
Insider
First SEC filing: June 11, 2026 · Latest: June 11, 2026
Insider at
Insider transactions
0 buys (P)
0 sells (S)
Net: $0
Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted
| Date | Ticker | Code | Shares | Price | Value | Owned after | Δ own | A/D | vs now |
|---|---|---|---|---|---|---|---|---|---|
| June 23, 2026 | SPRO | A | 20,000 | · | · | 20,000 Direct | · | Acquired | (price as of 2026-10-02) |
| June 23, 2026 | SPRO | A | 10,000 | · | · | 85,000 Direct | +13.33% | Acquired | (price as of 2026-10-02) |
| June 18, 2026 | AGIO | A | 14,950 | · | · | 14,950 Direct | · | Acquired | (price as of 2026-10-02) |
| June 18, 2026 | AGIO | A | 2,927 | · | · | 2,927 Direct | · | Acquired | (price as of 2026-10-02) |
| June 18, 2026 | AGIO | M | 2,816 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-02) |
| June 18, 2026 | AGIO | M | 2,816 | · | · | 15,230 Direct | +22.68% | Acquired | (price as of 2026-10-02) |
| June 17, 2026 | AKBA | A | 53,600 | · | · | 53,600 Direct | · | Acquired | (price as of 2026-10-02) |
| June 17, 2026 | AKBA | A | 35,700 | · | · | 196,633 Direct | +22.18% | Acquired | (price as of 2026-10-02) |
| June 15, 2026 | TARA | A | 31,000 | · | · | 31,000 Direct | · | Acquired | (price as of 2026-10-02) |
| June 9, 2026 | TVRD | A | 6,000 | · | · | 6,000 Direct | · | Acquired | (price as of 2026-10-02) |
| Aug. 11, 2025 | AGIO | M | 2,302 | · | · | 12,414 Direct | +22.77% | Acquired | (price as of 2026-10-02) |
| Aug. 11, 2025 | AGIO | M | 2,302 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-02) |
| June 20, 2025 | AGIO | M | 2,120 | · | · | 10,112 Direct | +26.53% | Acquired | (price as of 2026-10-02) |
| June 20, 2025 | AGIO | M | 2,120 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-02) |
| June 18, 2025 | AGIO | A | 2,816 | · | · | 2,816 Direct | · | Acquired | (price as of 2026-10-02) |
| June 18, 2025 | AGIO | A | 15,768 | · | · | 15,768 Direct | · | Acquired | (price as of 2026-10-02) |
| June 12, 2025 | SPRO | A | 20,000 | · | · | 75,000 Direct | +36.36% | Acquired | (price as of 2026-10-02) |
| June 12, 2025 | TARA | A | 24,000 | · | · | 24,000 Direct | · | Acquired | (price as of 2026-10-02) |
| June 10, 2025 | AKBA | A | 35,700 | · | · | 160,933 Direct | +28.51% | Acquired | (price as of 2026-10-02) |
| June 10, 2025 | AKBA | A | 53,600 | · | · | 53,600 Direct | · | Acquired | (price as of 2026-10-02) |
| April 17, 2025 | TVRD | A | 12,000 | · | · | 12,000 Direct | · | Acquired | (price as of 2026-10-02) |
| Aug. 11, 2024 | AGIO | M | 2,302 | · | · | 7,992 Direct | +40.46% | Acquired | (price as of 2026-10-02) |
| Aug. 11, 2024 | AGIO | M | 2,302 | · | · | 2,302 Direct | -50.00% | Disposed | (price as of 2026-10-02) |
| June 20, 2024 | AGIO | A | 2,120 | · | · | 2,120 Direct | · | Acquired | (price as of 2026-10-02) |
| June 20, 2024 | AGIO | A | 11,774 | · | · | 11,774 Direct | · | Acquired | (price as of 2026-10-02) |
| June 13, 2024 | AGIO | M | 3,388 | · | · | 5,690 Direct | +147.18% | Acquired | (price as of 2026-10-02) |
| June 13, 2024 | AGIO | M | 3,388 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-02) |
| June 7, 2024 | TARA | A | 10,000 | · | · | 10,000 Direct | · | Acquired | (price as of 2026-10-02) |
| June 6, 2024 | AKBA | A | 30,000 | · | · | 125,233 Direct | +31.50% | Acquired | (price as of 2026-10-02) |
| June 6, 2024 | AKBA | A | 45,000 | · | · | 45,000 Direct | · | Acquired | (price as of 2026-10-02) |
| May 29, 2024 | SPRO | A | 20,000 | · | · | 55,000 Direct | +57.14% | Acquired | (price as of 2026-10-02) |
| Oct. 5, 2023 | SPRO | A | 20,000 | · | · | 35,000 Direct | +133.33% | Acquired | (price as of 2026-10-02) |
| Aug. 11, 2023 | AGIO | M | 2,302 | · | · | 2,302 Direct | · | Acquired | (price as of 2026-10-02) |
| Aug. 11, 2023 | AGIO | M | 2,302 | · | · | 4,604 Direct | -33.33% | Disposed | (price as of 2026-10-02) |
| June 13, 2023 | AGIO | A | 3,388 | · | · | 3,388 Direct | · | Acquired | (price as of 2026-10-02) |
| June 13, 2023 | AGIO | A | 18,958 | · | · | 18,958 Direct | · | Acquired | (price as of 2026-10-02) |
| June 7, 2023 | TARA | A | 10,000 | · | · | 10,000 Direct | · | Acquired | (price as of 2026-10-02) |
| June 6, 2023 | AKBA | A | 30,000 | · | · | 95,233 Direct | +45.99% | Acquired | (price as of 2026-10-02) |
| June 6, 2023 | AKBA | A | 45,000 | · | · | 45,000 Direct | · | Acquired | (price as of 2026-10-02) |
| Sept. 15, 2022 | SPRO | A | 15,000 | · | · | 15,000 Direct | · | Acquired | (price as of 2026-10-02) |
| Aug. 11, 2022 | AGIO | A | 37,947 | · | · | 37,947 Direct | · | Acquired | (price as of 2026-10-02) |
| Aug. 11, 2022 | AGIO | A | 6,906 | · | · | 6,906 Direct | · | Acquired | (price as of 2026-10-02) |
| June 8, 2022 | AKBA | A | 13,700 | · | · | 65,233 Direct | +26.58% | Acquired | (price as of 2026-10-02) |
| June 8, 2022 | AKBA | A | 20,100 | · | · | 20,100 Direct | · | Acquired | (price as of 2026-10-02) |
| June 8, 2022 | TARA | A | 10,000 | · | · | 10,000 Direct | · | Acquired | (price as of 2026-10-02) |
| Aug. 17, 2021 | SPRO | A | 7,500 | · | · | 7,500 Direct | · | Acquired | (price as of 2026-10-02) |
| June 9, 2021 | TARA | A | 10,000 | · | · | 10,000 Direct | · | Acquired | (price as of 2026-10-02) |
| June 2, 2021 | AKBA | A | 13,700 | · | · | 51,533 Direct | +36.21% | Acquired | (price as of 2026-10-02) |
| June 2, 2021 | AKBA | A | 20,100 | · | · | 20,100 Direct | · | Acquired | (price as of 2026-10-02) |
| Jan. 29, 2021 | TARA | A | 3,750 | · | · | 21,750 Direct | +20.83% | Acquired | (price as of 2026-10-02) |
| Jan. 29, 2021 | TARA | A | 18,000 | · | · | 18,000 Direct | · | Acquired | (price as of 2026-10-02) |
| Jan. 4, 2021 | SPRO | A | 2,629 | $13.31 | $34,992 | 2,629 Direct | · | Acquired | -91.1% (price as of 2026-10-02) |
| Oct. 27, 2020 | SPRO | A | 7,500 | · | · | 7,500 Direct | · | Acquired | (price as of 2026-10-02) |
| June 8, 2020 | AKBA | S 10b5-1 | 4,567 | $12.10 | $55,261 | 37,833 Direct | -10.77% | Disposed | -92.9% (price as of 2026-10-02) |
| June 5, 2020 | AKBA | A | 13,700 | · | · | 42,400 Direct | +47.74% | Acquired | (price as of 2026-10-02) |
| June 5, 2020 | AKBA | A | 20,100 | · | · | 20,100 Direct | · | Acquired | (price as of 2026-10-02) |
| Nov. 20, 2019 | AKBA | P | 15,000 | $3.52 | $52,800 | 28,700 Direct | +109.49% | Acquired | -75.4% (price as of 2026-10-02) |
| June 6, 2019 | AKBA | A | 13,700 | · | · | 13,700 Direct | · | Acquired | (price as of 2026-10-02) |
| June 6, 2019 | AKBA | A | 20,100 | · | · | 20,100 Direct | · | Acquired | (price as of 2026-10-02) |
| June 5, 2019 | SPRO | A | 6,073 | · | · | 6,073 Direct | · | Acquired | (price as of 2026-10-02) |
| March 29, 2019 | SPRO | A | 12,146 | · | · | 12,146 Direct | · | Acquired | (price as of 2026-10-02) |
| Aug. 28, 2018 | AKBA | A | 25,000 | · | · | 25,000 Direct | · | Acquired | (price as of 2026-10-02) |
P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding
Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.
Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.
| Date | Ticker | Security | Underlying | Exercise price | Expiration | Shares | A/D |
|---|---|---|---|---|---|---|---|
| June 23, 2026 | SPRO | Stock Option (right to buy) | Common Stock | $2.15 | June 23, 2036 | 20,000 | Acquired |
| June 18, 2026 | AGIO | Stock options (right to buy) | Common stock | $34.16 | June 18, 2036 | 14,950 | Acquired |
| June 18, 2026 | AGIO | Restricted stock units | Common stock | · | · | 2,927 | Acquired |
| June 18, 2026 | AGIO | Restricted stock units | Common stock | · | · | 2,816 | Disposed |
| June 17, 2026 | AKBA | Stock Option (Right to buy) | Common Stock | $1.02 | June 17, 2036 | 53,600 | Acquired |
| June 15, 2026 | TARA | Stock Option (Right to Buy) | Common Stock | $3.94 | June 14, 2036 | 31,000 | Acquired |
| June 9, 2026 | TVRD | Stock Option (right to buy) | Common Stock | $2.78 | June 8, 2036 | 6,000 | Acquired |
| Aug. 11, 2025 | AGIO | Restricted stock units | Common stock | · | · | 2,302 | Disposed |
| June 20, 2025 | AGIO | Restricted stock units | Common stock | · | · | 2,120 | Disposed |
| June 18, 2025 | AGIO | Restricted stock units | Common stock | · | · | 2,816 | Acquired |
| June 18, 2025 | AGIO | Stock options (right to buy) | Common stock | $35.50 | June 18, 2035 | 15,768 | Acquired |
| June 12, 2025 | TARA | Stock Option (Right to Buy) | Common Stock | $3.26 | June 11, 2035 | 24,000 | Acquired |
| June 10, 2025 | AKBA | Stock Option (Right to buy) | Common Stock | $3.92 | June 10, 2035 | 53,600 | Acquired |
| April 17, 2025 | TVRD | Stock Option (right to buy) | Common Stock | $17.04 | April 16, 2035 | 12,000 | Acquired |
| Aug. 11, 2024 | AGIO | Restricted stock units | Common stock | · | · | 2,302 | Disposed |
| June 20, 2024 | AGIO | Restricted stock units | Common stock | · | · | 2,120 | Acquired |
| June 20, 2024 | AGIO | Stock options (right to buy) | Common stock | $42.45 | June 20, 2034 | 11,774 | Acquired |
| June 13, 2024 | AGIO | Restricted stock units | Common stock | · | · | 3,388 | Disposed |
| June 7, 2024 | TARA | Stock Option (Right to Buy) | Common Stock | $2.67 | June 6, 2034 | 10,000 | Acquired |
| June 6, 2024 | AKBA | Stock Option (Right to buy) | Common Stock | $1.07 | June 6, 2034 | 45,000 | Acquired |
| Aug. 11, 2023 | AGIO | Restricted stock units | Common stock | · | · | 2,302 | Disposed |
| June 13, 2023 | AGIO | Restricted stock units | Common stock | · | · | 3,388 | Acquired |
| June 13, 2023 | AGIO | Stock options (right to buy) | Common stock | $26.56 | June 13, 2033 | 18,958 | Acquired |
| June 7, 2023 | TARA | Stock Option (Right to Buy) | Common Stock | $2.85 | June 6, 2033 | 10,000 | Acquired |
| June 6, 2023 | AKBA | Stock Option (Right to buy) | Common Stock | $1.20 | June 6, 2033 | 45,000 | Acquired |
| Aug. 11, 2022 | AGIO | Stock option (right to buy) | Common stock | $25.99 | Aug. 11, 2032 | 37,947 | Acquired |
| Aug. 11, 2022 | AGIO | Restricted stock units | Common stock | · | · | 6,906 | Acquired |
| June 8, 2022 | AKBA | Stock Option (Right to buy) | Common Stock | $0.45 | June 8, 2032 | 20,100 | Acquired |
| June 8, 2022 | TARA | Stock Option (Right to Buy) | Common Stock | $3.50 | June 7, 2032 | 10,000 | Acquired |
| Aug. 17, 2021 | SPRO | Stock Option (right to buy) | Common Stock | $13.69 | Aug. 27, 2031 | 7,500 | Acquired |
| June 9, 2021 | TARA | Stock Option (Right to Buy) | Common Stock | $10.51 | June 8, 2031 | 10,000 | Acquired |
| June 2, 2021 | AKBA | Stock Option (Right to buy) | Common Stock | $3.37 | June 2, 2031 | 20,100 | Acquired |
| Jan. 29, 2021 | TARA | Stock Option (Right to Buy) | Common Stock | $17.98 | Jan. 28, 2031 | 3,750 | Acquired |
| Jan. 29, 2021 | TARA | Stock Option (Right to Buy) | Common Stock | $17.98 | Jan. 28, 2031 | 18,000 | Acquired |
| Jan. 4, 2021 | SPRO | Stock Option (right to buy) | Common Stock | $17.93 | Jan. 4, 2031 | 2,629 | Acquired |
| Oct. 27, 2020 | SPRO | Stock Option (right to buy) | Common Stock | $13.52 | Oct. 27, 2030 | 7,500 | Acquired |
| June 5, 2020 | AKBA | Stock Option (Right to buy) | Common Stock | $11.96 | June 5, 2030 | 20,100 | Acquired |
| June 6, 2019 | AKBA | Stock Option (Right to buy) | Common Stock | $4.23 | June 6, 2029 | 20,100 | Acquired |
| June 5, 2019 | SPRO | Stock Option (right to buy) | Common Stock | $10.67 | June 5, 2029 | 6,073 | Acquired |
| March 29, 2019 | SPRO | Stock Option (right to buy) | Common Stock | $12.81 | March 29, 2029 | 12,146 | Acquired |
| Aug. 28, 2018 | AKBA | Stock Option (Right to buy) | Common Stock | $8.25 | Aug. 28, 2028 | 25,000 | Acquired |
Exercise/conversion price is blank when not applicable (e.g. RSUs).