TVRD Tvardi Therapeutics, Inc. - Common Stock
$1.97
Price · Aug 19, 2026
Fundamentals as of Aug 14, 2026
52W Range
$2–$44
1% of range
Analyst Rating
BUY
15 analysts
Price Target
$8
+333% upside
P/E (TTM)
-0.6
ROE
-67.6%
Net Profit Margin
—
TVRD Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$1.97
Market Cap
$18M
P/E (TTM)
-0.6
EPS (TTM)
$-3.26
Revenue (TTM)
$7M
Div Yield
—
ROE
-67.6%
Debt/Equity
—
52W Range
$2 – $44
TVRD Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$7M
2016-12-31
→
2024-12-31
EPS
$-3.26
2018-12-31
→
2025-12-31
Free Cash Flow
—
2016-12-31
→
2024-12-31
Margins
—
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
TVRD
Peer Median
P/E (TTM)
-0.6
53.4
P/S (TTM)
2.2
6.8
P/B
0.9
1.5
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
TVRD
Peer Median
ROA
-54.1%
-33.0%
ROE
-67.6%
-4.5%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
TVRD
Peer Median
Current Ratio
2.9
1.7
Quick Ratio
2.8
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
TVRD
Peer Median
Revenue YoY
-66.0%
—
Revenue CAGR 3Y
-32.3%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
TVRD
Peer Median
TVRD Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
15 analysts
- Strong Buy 4 26.7%
- Buy 8 53.3%
- Hold 2 13.3%
- Sell 1 6.7%
- Strong Sell 0 0.0%
12-Month Price Target
8 analysts · 2026-08-16
Median
$9.50
Mean
$8.50
← Below all targets
$1.97
Low
$3.00
High
$13.00
Median target
$9.50
+383.5%
Mean target
$8.50
+332.6%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-0.36%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $-0.73 | $-0.76 | 0.03% |
| Dec. 31, 2025 | $-0.78 | $-0.66 | -0.12% |
| Sept. 30, 2025 | $-0.59 | $-1.02 | 0.43% |
| June 30, 2025 | $-1.00 | $-0.58 | -0.42% |
| March 31, 2025 | $-3.22 | $-0.36 | -2.9% |
| Sept. 30, 2024 | $-8.28 | $-9.06 | 0.78% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| TVRD | $40M | -1.3 | -66.0% | — | -67.6% | — |
| AYTU | $20M | -3.0 | 1.8% | -20.4% | -54.5% | 69.0% |
| TXMD | $19M | -32.6 | 71.6% | -18.8% | -2.1% | — |
| QCLS | — | -0.5 | — | — | — | — |
| BFRI | — | — | — | — | — | — |
| COCP | $14M | -1.3 | — | — | -151.4% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 16
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | $7M | $21M | $42M | $23M | $135M | $20M | $13M | $911.0K | $86.0K | $4M | $3M | |
| Cost of Revenue | · | · | · | · | $0 | · | · | · | · | · | · | · | |
| R&D Expense | $18M | $24M | $109M | $92M | $83M | $108M | $114M | $76M | $49M | $49M | $21M | $15M | |
| SG&A Expense | $9M | $4M | $28M | $30M | $29M | $22M | $18M | $15M | $12M | $9M | $8M | $6M | |
| Operating Expenses | $27M | $28M | $142M | $129M | $112M | $130M | $132M | $91M | $60M | $58M | $29M | $21M | |
| Operating Income | $-27M | $-28M | $-121M | $-88M | $-89M | $5M | $-112M | $-77M | $-59M | $-58M | $-25M | $-18M | |
| Interest Income | $700.0K | $700.0K | · | · | · | · | · | · | · | · | · | · | |
| Other Non-op | $7M | $-2M | $4M | $2M | $642.0K | $2M | $4M | $3M | $1M | $652.0K | $101.0K | $126.0K | |
| Pretax Income | · | $-71M | $-119M | $-85M | $-88M | $8M | $-107M | $-74M | $-58M | $-58M | $-25M | $-18M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $-691.0K | $-816.0K | $-389.0K | $-204.0K | $-468.0K | $-397.0K | $-201.0K | |
| Net Income | $-18M | $-29M | $-119M | $-85M | $-88M | $8M | $-106M | $-74M | $-58M | $-57M | $-25M | $-18M | |
| EPS (Basic) | $-2.46 | $-11.42 | $-26.26 | $-19.12 | $-1.74 | $0.18 | $-2.49 | $-2.06 | · | · | · | · | |
| EPS (Diluted) | $-3.26 | $-11.42 | $-26.26 | $-19.12 | $-1.74 | $0.18 | $-2.49 | $-2.06 | · | · | · | · | |
| Shares (Basic) | 7,419,060 | 2,574,233 | 4,512,422 | 4,471,130 | 50,718,765 | 47,413,250 | 42,669,333 | 35,892,786 | 31,202,842 | 27,279,008 | 24,620,372 | 20,965,935 | |
| Shares (Diluted) | 7,783,182 | 2,574,233 | 4,512,422 | 4,471,130 | 50,718,765 | 47,915,030 | 42,669,333 | 35,892,786 | 31,202,842 | 27,279,008 | 24,620,372 | 20,965,935 | |
| EBITDA | $-27M | $-58M | $-121M | $-87M | $-89M | $6M | $-111M | $-77M | $-59M | $-57M | $-24M | $-17M |
Balance Sheet 24
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $21M | $32M | $52M | $64M | $13M | $32M | $18M | $15M | $9M | $12M | $15M | $53M | |
| Short-term Investments | $10M | · | · | · | · | · | · | · | · | $46M | $92M | · | |
| Receivables | · | $407.0K | $3M | $3M | · | · | · | · | · | · | · | · | |
| Inventory | · | $900.0K | $3M | $2M | $3M | · | · | · | · | · | · | · | |
| Prepaid Expense | $727.0K | $72.0K | $8M | $16M | $3M | $12M | $9M | $5M | $2M | $2M | $2M | $287.0K | |
| Current Assets | $32M | $32M | $116M | $169M | $173M | $195M | $166M | $168M | $95M | $61M | $109M | $53M | |
| PP&E (Net) | $52.0K | $84.0K | $3M | $426.0K | $631.0K | $840.0K | $700.0K | $880.0K | $1M | $2M | $1M | $2M | |
| PP&E (Gross) | · | · | $5M | $2M | $2M | $2M | $2M | $2M | $2M | $10M | $8M | $8M | |
| Accum. Depreciation | · | · | $2M | $1M | $1M | $2M | $1M | $1M | $764.0K | $8M | $7M | $6M | |
| Intangibles | $322.0K | $385.0K | · | · | · | · | · | · | · | · | · | · | |
| Other Non-current Assets | $17.0K | $17.0K | · | · | · | · | · | · | · | · | · | · | |
| Total Assets | $32M | $35M | $126M | $182M | $247M | $271M | $233M | $191M | $97M | $64M | $111M | $56M | |
| Accounts Payable | $3M | $2M | $12M | $10M | $6M | $5M | $9M | $4M | $4M | $5M | $2M | $515.0K | |
| Accrued Liabilities | $8M | $8M | · | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $11M | $10M | $26M | $23M | $18M | $18M | $43M | $40M | $9M | $12M | $5M | $3M | |
| Capital Leases | $85.0K | $201.0K | $6M | · | $2M | $4M | $3M | · | · | · | · | · | |
| Total Liabilities | $11M | $41M | $69M | $23M | · | · | · | · | · | · | · | · | |
| Common Stock | $9.0K | $2.0K | $5.0K | $53.0K | $53.0K | $50.0K | $47.0K | $39.0K | $33.0K | $27.0K | $27.0K | $23.0K | |
| Paid-in Capital | $131M | $1M | · | · | · | · | · | · | · | · | · | · | |
| Retained Earnings | $-110M | $-92M | $-685M | $-566M | $-481M | $-392M | $-401M | $-294M | $-220M | $-162M | $-105M | $-80M | |
| AOCI | $8.0K | · | $-260.0K | $-2M | $-358.0K | $73.0K | $170.0K | $-114.0K | $-70.0K | $3.0K | $-35.0K | $0 | |
| Stockholders' Equity | $21M | $-91M | $-62M | $159M | $228M | $249M | $187M | $134M | $87M | $51M | $105M | $52M | |
| Liabilities + Equity | $32M | $35M | $126M | $182M | $247M | $271M | $233M | $191M | $97M | $64M | $111M | $56M | |
| Shares Outstanding | 9,381,344 | 2,574,767 | 4,540,059 | 53,797,341 | 53,480,812 | 49,872,213 | 46,720,225 | 39,547,558 | 32,662,255 | 27,296,863 | 27,254,863 | 22,802,039 |
Cash Flow 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $95.0K | $95.0K | $259.0K | $248.0K | $248.0K | $209.0K | $198.0K | $370.0K | $495.0K | $1M | $839.0K | $783.0K | |
| Stock-based Comp | $1M | $319.0K | $14M | $18M | $21M | $15M | $13M | $9M | $6M | $3M | $3M | $1M | |
| Deferred Tax | · | · | · | · | · | · | · | $0 | $0 | $0 | $0 | $0 | |
| Restructuring | · | $6M | · | · | · | · | · | · | · | · | · | · | |
| Other Non-cash | $-7M | $829.0K | $12M | $-11M | $7M | $-29M | $-16M | $42M | $-3M | $6M | $-141.0K | $-2M | |
| Operating Cash Flow | $-23M | $-18M | $-92M | $-79M | $-60M | $-5M | $-109M | $-22M | $-55M | $-47M | $-21M | $-18M | |
| CapEx | · | $1M | $2M | $43.0K | $39.0K | $349.0K | $18.0K | $73.0K | $58.0K | $717.0K | $20.0K | $42.0K | |
| Investing Cash Flow | $-10M | $49M | $43M | $129M | $-5M | $-20M | $-31M | $-83M | $-36M | $45M | · | · | |
| Stock Issued | · | · | $1M | · | · | · | $136M | $92M | $86M | · | $75M | $100.0K | |
| Net Stock Activity | · | · | $1M | · | · | · | $136M | $92M | $86M | · | · | $100.0K | |
| Financing Cash Flow | $23M | $27M | $38M | $311.0K | $47M | $39M | $143M | $111M | $88M | $123.0K | · | · | |
| Net Change in Cash | $-11M | $9M | · | · | · | · | · | · | $-3M | $-3M | $-38M | $40M | |
| Taxes Paid | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Free Cash Flow | · | $-62M | $-94M | $-79M | $-60M | $-6M | $-109M | $-22M | $-55M | $-48M | $-21M | $-18M |
Profitability 7
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | -818.0% | -579.4% | -209.1% | -386.9% | 4.0% | -561.6% | · | -6529.6% | -67907.0% | -662.3% | -568.8% | |
| Net Margin | · | -993.0% | -565.2% | -204.2% | -384.1% | 6.2% | -534.9% | · | -6380.4% | -66604.7% | -649.2% | -558.5% | |
| Pretax Margin | · | -998.5% | · | -204.2% | -384.1% | 5.7% | -539.0% | · | -6402.7% | -67148.8% | -659.7% | -564.9% | |
| EBITDA Margin | · | -815.3% | -578.2% | -208.5% | -385.8% | 4.1% | -560.6% | · | -6475.3% | -66203.5% | -640.3% | -544.2% | |
| ROA | -54.1% | -83.5% | -76.9% | -39.8% | -34.1% | 3.3% | -50.2% | -51.4% | -72.3% | -65.6% | -29.6% | -47.9% | |
| ROE | -67.6% | 170.6% | -166.1% | -49.8% | -40.7% | 4.5% | -53.4% | -52.3% | -62.5% | -93.5% | -22.6% | -33.2% | |
| ROIC | · | 1264.0% | · | -55.1% | -39.1% | 2.4% | -59.4% | -57.6% | -68.3% | -114.2% | -23.6% | -34.6% |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.9 | 11.0 | 4.5 | 7.2 | 9.8 | 10.6 | 3.9 | 4.2 | 11.2 | 5.3 | 20.7 | 15.6 | |
| Quick Ratio | 2.8 | 9.6 | 2.1 | 2.7 | 0.8 | 1.7 | 0.4 | 0.4 | 1.1 | 5.1 | 20.3 | 15.5 |
Efficiency 3
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | 0.1 | 0.1 | 0.2 | 0.1 | 0.5 | 0.1 | · | 0.0 | 0.0 | 0.0 | 0.1 | |
| Inventory Turnover | · | · | · | · | 0.0 | · | · | · | · | · | · | · | |
| Receivables Turnover | · | 4.5 | 7.0 | · | · | · | · | · | · | · | · | · |
Growth Rates 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | · | -66.0% | -49.9% | 81.8% | -83.0% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | · | -32.3% | -46.3% | · | · | · | · | · | · | · | · | · |
Valuation (TTM) 10
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $8M | $7M | $21M | $42M | $23M | $135M | $20M | $13M | $911.0K | $86.0K | $4M | $3M | |
| Net Income TTM | $-18M | $-29M | $-119M | $-85M | $-88M | $8M | $-106M | $-74M | $-58M | $-57M | $-25M | $-18M | |
| Market Cap | $40M | $84M | $1.46B | $20.80B | $23.45B | $27.16B | $27.10B | $18.51B | $14.39B | $9.13B | $16.54B | $8.18B | |
| P/E | -1.3 | -1.6 | -1.0 | -20.2 | -252.0 | 3026.0 | -232.9 | -227.2 | -317.0 | -240.6 | -436.7 | -258.2 | |
| P/S | 4.9 | 11.8 | 69.5 | 496.8 | 1018.3 | 201.1 | 1362.6 | 1374.1 | 15798.3 | 106153.1 | 4349.9 | 2576.0 | |
| P/B | 1.9 | -18.3 | 25.5 | 131.0 | 103.1 | 109.1 | 145.1 | 138.5 | 165.8 | 180.0 | 157.5 | 158.4 | |
| P / Tangible Book | 2.0 | · | · | 131.0 | 103.1 | 109.1 | · | · | · | · | · | · | |
| P / Cash Flow | -1.7 | -1.4 | -15.8 | -264.2 | -390.3 | -4950.7 | -248.1 | -829.9 | -262.5 | -192.7 | -770.2 | -463.9 | |
| P / FCF | · | -1.4 | -15.4 | -264.1 | -390.0 | -4654.6 | -248.0 | -827.2 | -262.2 | -189.8 | -769.5 | -462.8 | |
| Earnings Yield | -75.8% | -62.2% | -98.2% | -5.0% | -0.40% | 0.03% | -0.43% | -0.44% | -0.32% | -0.42% | -0.23% | -0.39% |
Income Statement 14
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | $3M | · | $3M | $991.0K | $2M | $3M | $5M | $7M | $6M | $11M | $23M | |
| R&D Expense | $4M | $5M | $8M | $4M | $6M | $3M | $-10M | $5M | $7M | $22M | $28M | $25M | $30M | $24M | $25M | $20M | |
| SG&A Expense | $3M | $2M | $-1M | $2M | $3M | $1M | $-4M | $881.0K | $650.0K | $7M | $7M | $7M | $8M | $7M | $7M | $8M | |
| Operating Expenses | $7M | $7M | $7M | $6M | $9M | $4M | $-17M | $6M | $7M | $32M | $36M | $34M | $39M | $34M | $35M | $27M | |
| Operating Income | $-7M | $-7M | $-10M | $-6M | $-9M | $-4M | $14M | $-6M | $-7M | $-30M | $-33M | $-29M | $-32M | $-28M | $-24M | $-4M | |
| Interest Income | $200.0K | · | $100.0K | $300.0K | $100.0K | · | $100.0K | $200.0K | $200.0K | · | · | · | · | · | · | · | |
| Other Non-op | · | · | $0 | $0 | $13M | $347.0K | $-4M | $766.0K | $689.0K | $952.0K | $874.0K | $866.0K | $861.0K | $985.0K | $665.0K | $266.0K | |
| Income Tax | · | · | · | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-6M | $-7M | $-7M | $-6M | $4M | $-10M | $-13M | $-6M | $-7M | $-4M | $-32M | $-28M | $-31M | $-27M | $-23M | $-4M | |
| EPS (Basic) | $-0.69 | $-0.73 | $0.84 | $-0.59 | $0.51 | $-3.72 | $13.67 | $-2.14 | $-2.71 | $-20.24 | $-24.67 | $-0.52 | $-0.58 | $-0.49 | $-0.43 | $-0.08 | |
| EPS (Diluted) | $-0.69 | $-0.73 | $1.55 | $-0.59 | $-1.00 | $-3.72 | $13.67 | $-2.14 | $-2.71 | $-20.24 | $-24.67 | $-0.52 | $-0.58 | $-0.49 | $-0.43 | $-0.08 | |
| Shares (Basic) | 9,381,344 | 9,381,344 | -11,728,717 | 9,377,079 | 8,246,582 | 2,575,462 | -4,091,637 | 2,574,767 | 2,574,767 | 1,516,336 | -157,598,299 | 54,235,695 | 54,002,988 | 53,872,038 | 53,726,123 | 53,614,668 | |
| Shares (Diluted) | 9,381,344 | 9,381,344 | -11,573,236 | 9,377,079 | 8,455,223 | 2,575,462 | -4,091,637 | 2,574,767 | 2,574,767 | 1,516,336 | -157,598,299 | 54,235,695 | 54,002,988 | 53,872,038 | 53,726,123 | 53,614,668 | |
| EBITDA | $-7M | $-7M | · | $-6M | $-9M | $-2M | · | $-6M | $-17M | $-30M | · | $-29M | $-32M | $-28M | $-24M | $-4M |
Balance Sheet 24
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $16M | $20M | $21M | $21M | $21M | $34M | $32M | $37M | $49M | $47M | $52M | $63M | $58M | $47M | $43M | $47M | |
| Short-term Investments | · | $5M | $10M | $15M | $20M | · | · | · | · | · | · | · | · | · | · | · | |
| Receivables | · | · | · | · | · | $1M | · | $435.0K | $359.0K | $2M | $3M | $3M | · | · | · | · | |
| Inventory | · | · | · | · | · | $900.0K | · | $625.0K | $2M | $3M | $3M | $3M | $3M | $4M | $2M | $3M | |
| Prepaid Expense | $1M | $345.0K | $727.0K | $2M | $2M | $2M | $72.0K | $2M | $4M | $6M | $8M | $13M | $15M | $17M | $19M | $6M | |
| Current Assets | $17M | $25M | $32M | $38M | $43M | · | $32M | $48M | $64M | $81M | $116M | $101M | $125M | $143M | $187M | $176M | |
| PP&E (Net) | $36.0K | $44.0K | $52.0K | $60.0K | $68.0K | · | $84.0K | $3M | $3M | $4M | $3M | $1M | $308.0K | $368.0K | $487.0K | $549.0K | |
| PP&E (Gross) | · | · | · | · | · | · | · | · | · | · | $5M | · | · | · | · | · | |
| Accum. Depreciation | · | · | · | · | · | · | · | · | · | · | $2M | · | · | · | · | · | |
| Intangibles | $291.0K | $306.0K | $322.0K | $338.0K | $354.0K | · | $385.0K | · | · | · | · | · | · | · | · | · | |
| Other Non-current Assets | $17.0K | $17.0K | $17.0K | $17.0K | $17.0K | · | $17.0K | · | · | · | · | · | · | · | · | · | |
| Total Assets | $18M | $26M | $32M | $39M | $44M | $39M | $35M | $51M | $72M | $90M | $126M | $115M | $134M | $153M | $214M | $227M | |
| Accounts Payable | $5M | $5M | $3M | $4M | $2M | $4.0K | $2M | $3M | $7M | $5M | $12M | $8M | $12M | $4M | $15M | $10M | |
| Accrued Liabilities | $4M | $7M | $8M | $7M | $8M | · | $8M | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $9M | $11M | $11M | $11M | $11M | $1M | $10M | $10M | $14M | $15M | $26M | $23M | $25M | $17M | $28M | $21M | |
| Capital Leases | $22.0K | $54.0K | $85.0K | $115.0K | $145.0K | · | $201.0K | · | $7M | $7M | $6M | $7M | · | · | $497.0K | $983.0K | |
| Total Liabilities | $9M | $11M | $11M | $11M | $11M | $47M | $41M | $51M | $61M | $60M | $69M | · | · | · | · | · | |
| Common Stock | $9.0K | $9.0K | $9.0K | $9.0K | $9.0K | $2.0K | $2.0K | $54.0K | $54.0K | $54.0K | $5.0K | $54.0K | $54.0K | $54.0K | $53.0K | $53.0K | |
| Paid-in Capital | $132M | $132M | $131M | $131M | $131M | · | $1M | · | · | · | · | · | · | · | · | · | |
| Retained Earnings | $-124M | $-117M | $-110M | $-103M | $-98M | $-761M | $-92M | $-748M | $-735M | $-715M | $-685M | $-652M | $-624M | $-593M | $-536M | $-513M | |
| AOCI | · | $1.0K | $8.0K | $7.0K | $-13.0K | · | · | $-25.0K | $-121.0K | $-191.0K | $-260.0K | $-439.0K | $-730.0K | $-1M | $-2M | $-2M | |
| Stockholders' Equity | $8M | $15M | $21M | $28M | $33M | $-8M | $-91M | $707.0K | $12M | $30M | $57M | $86M | $109M | $137M | $185M | $204M | |
| Liabilities + Equity | $18M | $26M | $32M | $39M | $44M | $39M | $35M | $51M | $72M | $90M | $126M | $115M | $134M | $153M | $214M | $227M | |
| Shares Outstanding | 9,381,344 | 9,381,344 | 9,381,344 | 9,379,332 | 9,373,433 | 1,524,535 | 2,574,767 | 54,846,639 | 54,837,764 | 54,667,079 | 4,540,059 | 54,471,829 | 54,068,806 | 53,974,352 | 53,733,607 | 53,710,300 |
Cash Flow 12
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $23.0K | $24.0K | $24.0K | $24.0K | $47.0K | $24.0K | $24.0K | $-48.0K | $5.0K | $42.0K | $82.0K | $59.0K | $60.0K | $58.0K | $61.0K | $63.0K | |
| Stock-based Comp | $335.0K | $370.0K | $353.0K | $339.0K | $-719.0K | $80.0K | $79.0K | $-5M | $-3M | $3M | $4M | $3M | $3M | $3M | $4M | $5M | |
| Deferred Tax | $0 | $0 | · | $0 | $0 | $0 | · | $0 | $0 | · | · | · | · | · | · | · | |
| Restructuring | · | · | · | · | · | $0 | · | $707.0K | $3M | $2M | · | · | · | · | · | · | |
| Other Non-cash | · | $551.0K | · | · | · | $-1M | · | · | · | $-3M | · | · | · | $-11M | · | · | |
| Operating Cash Flow | $-9M | $-6M | $-6M | $-4M | $-9M | $-8M | $-5M | $29M | $24M | $-30M | $-17M | $-20M | $-20M | $-35M | $-25M | $-5M | |
| CapEx | · | · | · | · | · | · | · | $0 | $210.0K | $836.0K | $2M | · | · | · | $0 | $0 | |
| Investing Cash Flow | $5M | $5M | $5M | $5M | $-10M | $-11M | · | $2M | $15M | $26M | $-30M | $23M | $33M | $18M | $21M | $30M | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | $0 | · | · | · | · | · | |
| Financing Cash Flow | · | · | $1.0K | $-322.0K | $22M | $-2M | $27M | $1M | $690.0K | $-685.0K | $36M | $1M | $0 | $560.0K | $104.0K | $182.0K | |
| Net Change in Cash | $-4M | $-883.0K | $-684.0K | $770.0K | $9M | $-20M | $22M | $-7M | · | · | · | · | · | · | · | · | |
| Free Cash Flow | · | · | · | · | · | · | · | · | · | $-31M | · | · | · | · | · | · |
Profitability 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | -92.9% | · | -234.3% | -1746.3% | -1389.5% | · | -593.9% | -466.5% | -448.5% | -220.5% | -19.4% | |
| Net Margin | · | · | · | · | · | -191.0% | · | -488.1% | -2019.8% | -1437.8% | · | -576.1% | -454.0% | -432.5% | -214.4% | -18.3% | |
| EBITDA Margin | · | · | · | · | · | -92.9% | · | -234.3% | -1746.3% | -1387.5% | · | -593.9% | -466.5% | -447.6% | -220.5% | -19.4% | |
| ROA | -21.1% | -21.0% | · | -12.2% | 7.2% | -7.6% | · | -15.0% | -19.4% | -25.2% | · | -17.1% | -17.4% | -14.1% | -10.6% | -1.9% | |
| ROE | -31.3% | -211.6% | · | -38.7% | 18.7% | -45.1% | · | -28.9% | -33.2% | -36.9% | · | -20.7% | -20.1% | -15.7% | -11.8% | -2.1% |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 1.9 | 2.2 | · | 3.5 | 4.0 | · | · | 4.8 | 4.6 | 5.4 | · | 4.4 | 4.9 | 8.6 | 6.6 | 8.3 | |
| Quick Ratio | 1.7 | 2.2 | · | 3.3 | 3.8 | 29.6 | · | 3.7 | 3.6 | 3.2 | · | 2.9 | 2.3 | 2.8 | 1.5 | 2.2 |
Efficiency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | |
| Receivables Turnover | · | · | · | · | · | 1.7 | · | 1.4 | 5.5 | 2.5 | · | 2.9 | · | · | · | · |
Valuation (TTM) 10
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $8M | $8M | · | $8M | $8M | $8M | · | $11M | $15M | $20M | · | $29M | $47M | $45M | $59M | · | |
| Net Income TTM | $-15M | $-18M | · | $-16M | $-18M | $-26M | · | $-45M | $-71M | $-90M | · | $-109M | $-86M | $-82M | $-56M | $-64M | |
| Market Cap | $18M | $30M | · | $366M | $219M | $23M | · | $608M | $509M | $1.79B | · | $3.29B | $5.51B | $9.54B | $18.11B | $17.65B | |
| P/E | -0.6 | -0.5 | · | -5.6 | -2.6 | -0.5 | · | -0.4 | -0.4 | -1.5 | · | -29.9 | -64.5 | -116.3 | -320.9 | -267.2 | |
| P/S | 2.2 | 3.6 | · | 44.3 | 26.5 | 2.8 | · | 57.7 | 34.1 | 89.1 | · | 114.5 | 117.4 | 213.1 | 307.5 | · | |
| P/B | 2.1 | 2.1 | · | 13.1 | 6.6 | -2.9 | · | 860.2 | 43.9 | 60.1 | · | 38.5 | 50.6 | 69.8 | 98.0 | 86.4 | |
| P / Tangible Book | 2.2 | 2.1 | · | 13.3 | 6.7 | · | · | 860.2 | 43.9 | 60.1 | · | 38.5 | 50.6 | 69.8 | 98.0 | 86.4 | |
| P / Cash Flow | · | -5.1 | · | · | · | -4.9 | · | · | · | -58.8 | · | · | · | -275.6 | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | -57.2 | · | · | · | · | · | · | |
| Earnings Yield | -158.4% | -189.9% | · | -17.8% | -38.9% | -186.1% | · | -231.0% | -258.9% | -66.6% | · | -3.3% | -1.6% | -0.86% | -0.31% | -0.37% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | — | $7M | $21M | $42M | $23M |
| Operating Margin % | — | -818.0% | -579.4% | -209.1% | -386.9% |
| Net Income | $-18M | $-29M | $-119M | $-85M | $-88M |
| Diluted EPS | $-3.26 | $-11.42 | $-26.26 | $-19.12 | $-1.74 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Current Ratio | 2.9 | 11.0 | 4.5 | 7.2 | 9.8 |
| Quick Ratio | 2.8 | 9.6 | 2.1 | 2.7 | 0.8 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | — | $-62M | $-94M | $-79M | $-60M |
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Institutional owners (13F) 63 filers · $5.2M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 17 (+2 vs prior Q) | 19 (+7 vs prior Q) | 7 (-10 vs prior Q) | 21 (+7 vs prior Q) | -122K |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| VANGUARD GROUP INC | $1,611,687 | 374,811 | 31.00% | Shares |
| Slate Path Capital LP | $1,337,824 | 704,118 | 25.73% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $654,326 | 344,382 | 12.58% | Shares |
| AMERICAN FINANCIAL GROUP INC | $424,952 | 223,659 | 8.17% | Shares |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $191,965 | 101,034 | 3.69% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $173,677 | 91,409 | 3.34% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $137,690 | 72,428 | 2.65% | Shares |
| Duncan Williams Asset Management, LLC | $120,158 | 63,241 | 2.31% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $84,949 | 44,710 | 1.63% | Shares |
| Russell Investments Group, Ltd. | $82,133 | 43,228 | 1.58% | Shares |
| STATE STREET CORP | $64,410 | 33,900 | 1.24% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $63,014 | 33,165 | 1.21% | Shares |
| Savant Capital, LLC | $49,434 | 19,462 | 0.95% | Shares |
| NORTHERN TRUST CORP | $41,485 | 21,834 | 0.80% | Shares |
| DIADEMA PARTNERS LP | $31,553 | 16,607 | 0.61% | Shares |
| XTX Topco Ltd | $28,249 | 14,868 | 0.54% | Shares |
| BROWN ADVISORY INC | $21,280 | 11,200 | 0.41% | Shares |
| Arax Advisory Partners | $20,906 | 11,003 | 0.40% | Shares |
| Qube Research & Technologies Ltd | $19,399 | 10,210 | 0.37% | Shares |
| Persistent Asset Partners Ltd | $8,081 | 4,253 | 0.16% | Shares |
| Vanguard Global Advisers, LLC | $6,460 | 3,400 | 0.12% | Shares |
| PNC Financial Services Group, Inc. | $5,879 | 3,094 | 0.11% | Shares |
| Tower Research Capital LLC (TRC) | $5,748 | 3,025 | 0.11% | Shares |
| CWM, LLC | $5,425 | 1,706 | 0.10% | Shares |
| FMR LLC | $2,457 | 1,293 | 0.05% | Shares |
| MERCER GLOBAL ADVISORS INC /ADV | $1,431 | 753 | 0.03% | Shares |
| BlackRock, Inc. | $1,322 | 696 | 0.03% | Shares |
| BARCLAYS PLC | $1,074 | 565 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $454 | 239 | 0.01% | Shares |
| GROUP ONE TRADING LLC | $407 | 214 | 0.01% | Shares |
| Allworth Financial LP | $301 | 158 | 0.01% | Shares |
| TD PRIVATE CLIENT WEALTH LLC | $283 | 149 | 0.01% | Shares |
| MORGAN STANLEY | $213 | 112 | 0.00% | Shares |
| JPMORGAN CHASE & CO | $187 | 98 | 0.00% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $162 | 85 | 0.00% | Shares |
| Integrated Wealth Concepts LLC | $118 | 61 | 0.00% | Shares |
| GAMMA Investing LLC | $76 | 40 | 0.00% | Shares |
| McIlrath & Eck, LLC | $64 | 20 | 0.00% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $55 | 29 | 0.00% | Shares |
| LRI Investments, LLC | $51 | 27 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $44 | 24 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $41 | 27 | 0.00% | Shares |
| GSA CAPITAL PARTNERS LLP | $34 | 17,885 | 0.00% | Shares |
| Farther Finance Advisors, LLC | $30 | 16 | 0.00% | Shares |
| HARBOUR INVESTMENTS, INC. | $29 | 15 | 0.00% | Shares |
| UBS Group AG | $29 | 15 | 0.00% | Shares |
| Leonteq Securities AG | $23 | 12 | 0.00% | Shares |
| WELLS FARGO & COMPANY/MN | $21 | 11 | 0.00% | Shares |
| ROTHSCHILD INVESTMENT LLC | $17 | 9 | 0.00% | Shares |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | $12 | 6 | 0.00% | Shares |
| IFP Advisors, Inc | $11 | 6 | 0.00% | Shares |
| Truvestments Capital LLC | $8 | 4 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $6 | 3 | 0.00% | Shares |
| Larson Financial Group LLC | $4 | 2 | 0.00% | Shares |
| COMERICA BANK | $4 | 1 | 0.00% | Shares |
| True Wealth Design, LLC | $4 | 2 | 0.00% | Shares |
| EverSource Wealth Advisors, LLC | $2 | 1 | 0.00% | Shares |
| Front Row Advisors LLC | $2 | 1 | 0.00% | Shares |
| Axiom Investment Management LLC | $2 | 1 | 0.00% | Shares |
| SJS Investment Consulting Inc. | $2 | 1 | 0.00% | Shares |
| CITIGROUP INC | $2 | 1 | 0.00% | Shares |
| FIFTH THIRD BANCORP | $2 | 1 | 0.00% | Shares |
| ROYAL BANK OF CANADA | $0 | 96 | 0.00% | Shares |
Company insiders 26 insiders · 12 officers · 15 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Christopher Posner | President and CEO | Nov. 2, 2023 S | 164,411 | 0 | 0 | $0 |
| Derek T Chalmers | President & CEO | Sept. 7, 2021 S | 991,405 | 0 | 0 | $0 |
| Ryan D Maynard | Chief Financial Officer | March 1, 2023 A | — | 0 | 0 | $0 |
| Mani Mohindru | CFO & Chief Strategy Officer | Dec. 4, 2019 S | 17,441 | 0 | 0 | $0 |
| Josef Schoell | Chief Financial Officer | July 26, 2017 M | 50,000 | 0 | 0 | $0 |
| Joana Goncalves | Chief Medical Officer | June 23, 2023 S | 53,681 | 0 | 0 | $0 |
| Scott Terrillion | Sec'y; Chief Compliance & G.C. | June 23, 2023 S | 88,563 | 0 | 0 | $0 |
| Frederique Menzaghi Ph.D. | Chief Scientific Off,SVP-R&D | June 23, 2023 S | 153,747 | 0 | 0 | $0 |
| Richard Makara | VP, Head of Accting;Controller | June 15, 2022 A | 13,583 | 0 | 0 | $0 |
| Joseph William Stauffer | Chief Medical Officer | Oct. 17, 2018 S | 2,000 | 0 | 0 | $0 |
| Michael E Lewis | Chief Scientific Advisor | March 8, 2017 A | 314,988 | 0 | 0 | $0 |
| Robert Medve | Chief Medical Officer | June 17, 2014 A | — | 0 | 0 | $0 |
| Susan Shiff Ph.D. | Director | June 9, 2026 A | — | 0 | 0 | $0 |
| Wallace L Hall JR | Director | June 9, 2026 A | — | 0 | 0 | $0 |
| Cynthia Smith | Director | June 9, 2026 A | — | 0 | 0 | $0 |
| Sujal Shah | Director | June 9, 2026 A | — | 0 | 0 | $0 |
| Michael S Wyzga | Director | June 9, 2026 A | — | 0 | 0 | $0 |
| Helen M Boudreau | Director | Aug. 2, 2023 A | — | 0 | 0 | $0 |
| Lisa Von Moltke | Director | June 1, 2023 A | 32,362 | 0 | 0 | $0 |
| Jeffrey L. Ives | Director | June 1, 2023 A | 47,838 | 0 | 0 | $0 |
| Martin Vogelbaum | Director | June 1, 2023 A | 109,712 | 0 | 0 | $0 |
| Harrison M Bains JR | Director | June 1, 2023 A | 57,438 | 0 | 0 | $0 |
| Dean Slagel | Director | June 29, 2017 S | 1,064,338 | 0 | 0 | $0 |
| Charles Moller Ph.D. | Director | Feb. 5, 2014 C | 1,576,404 | 0 | 0 | $0 |
| Edward Hurwitz | Director | Jan. 30, 2014 A | — | 0 | 0 | $0 |
| Thomas Charles Reilly | — | March 3, 2022 S | 37,811 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 1 position
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Vifor (International) Ltd., CSL Limited ×3 filings | April 16, 2025 | 2.20% | Amendment | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 7 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| ITWO · ProShares Trust | 0.00% | 284 NS | May 31, 2026 | N-PORT |
| RSSL · Global X Funds | 0.00% | 2,140 NS | April 30, 2026 | N-PORT |
| UWM · ProShares Trust | 0.00% | 220 NS | May 31, 2026 | N-PORT |
| URTY · ProShares Trust | 0.00% | 222 NS | May 31, 2026 | N-PORT |
| HDG · ProShares Trust | 0.00% | 6 NS | May 31, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | July 15, 2026 | Daily |
| VTI · VANGUARD INDEX FUNDS | — | — | July 15, 2026 | Daily |