TSHA Taysha Gene Therapies, Inc. - Common Stock
TSHA Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
TSHA Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
TSHA Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 6 33,3%
- Compra 11 61,1%
- Mantener 1 5,6%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
12 analistas · 2026-08-16Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.13 | $-0.12 | -0.01% |
| 31 de marzo de 2026 | $-0.12 | $-0.10 | -0.02% |
| 31 de diciembre de 2025 | $-0.08 | $-0.10 | 0.02% |
| 30 de septiembre de 2025 | $-0.09 | $-0.09 | 0.00% |
| 30 de junio de 2025 | $-0.09 | $-0.08 | -0.01% |
| 31 de marzo de 2025 | $-0.08 | $-0.09 | 0.01% |
| 31 de diciembre de 2024 | $-0.07 | $-0.08 | 0.01% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| TSHA | $1.57B | -16.2 | 17.3% | -1115.3% | -44.0% | — |
| PVLA | $1.30B | -28.2 | 65.3% | -1610.6% | -110.1% | — |
| AGIO | $1.59B | -3.8 | 48.0% | -764.0% | -32.2% | — |
| STOK | $1.87B | -264.5 | 404.5% | -3.7% | -2.0% | — |
| VRDN | $3.17B | -7.7 | 23359.9% | -483.6% | -55.4% | — |
| BHVN | $1.50B | -1.6 | — | — | -310.8% | — |
| SRPT | $2.26B | -3.0 | 15.6% | -32.5% | -57.1% | — |
| ZBIO | $1.98B | -4.3 | 100.0% | -3777.4% | -156.8% | — |
| DMRA | — | — | 38.3% | -17981.1% | -167.0% | — |
| SNDX | $1.84B | -6.4 | 627.8% | -165.6% | -257.1% | — |
| RXRX | $2.16B | -2.8 | 26.9% | -863.4% | -62.9% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 15
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue | $10M | $8M | $15M | $3M | |
| R&D Expense | $86M | $66M | $57M | $91M | |
| SG&A Expense | $34M | $29M | $30M | $37M | |
| Operating Expenses | $120M | $100M | $88M | $165M | |
| Operating Income | $-110M | $-91M | $-72M | $-162M | |
| Interest Expense | · | · | $5M | $4M | |
| Interest Income | $9M | $7M | $4M | · | |
| Other Non-op | $-291.0K | $-110.0K | $-47.0K | $-18.0K | |
| Income Tax | $0 | $0 | $0 | $0 | |
| Net Income | $-109M | $-89M | $-112M | $-166M | |
| EPS (Basic) | $-0.34 | $-0.36 | $-0.96 | $-3.78 | |
| EPS (Diluted) | $-0.34 | $-0.36 | $-0.96 | $-3.78 | |
| Shares (Basic) | 319,711,972 | 250,134,421 | 116,121,482 | 43,952,015 | |
| Shares (Diluted) | 319,711,972 | 250,134,421 | 116,121,482 | 43,952,015 | |
| EBITDA | $-110M | $-91M | $-72M | · |
Balance general 23
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $320M | $139M | $144M | $88M | |
| Prepaid Expense | $4M | $3M | $3M | $9M | |
| Other Current Assets | $802.0K | $308.0K | $292.0K | $466.0K | |
| Current Assets | $325M | $142M | $150M | $96M | |
| PP&E (Net) | $7M | $7M | $11M | $15M | |
| PP&E (Gross) | $11M | $11M | $14M | $17M | |
| Accum. Depreciation | $5M | $4M | $3M | $2M | |
| Other Non-current Assets | $183.0K | $217.0K | $304.0K | $1M | |
| Total Assets | $343M | $160M | $173M | $126M | |
| Accounts Payable | $6M | $4M | $6M | $11M | |
| Current Liabilities | $27M | $26M | $37M | $63M | |
| Capital Leases | $18M | $17M | $19M | $20M | |
| Other Non-current Liabilities | $2M | $1M | $2M | $4M | |
| Total Liabilities | $96M | $89M | $98M | $125M | |
| Long-term Debt | · | · | · | $38M | |
| Total Debt | $50M | $44M | $41M | · | |
| Common Stock | $3.0K | $2.0K | $2.0K | $1.0K | |
| Paid-in Capital | $958M | $678M | $588M | $402M | |
| Retained Earnings | $-711M | $-602M | $-513M | $-401M | |
| AOCI | $-192.0K | $-4M | · | · | |
| Stockholders' Equity | $247M | $72M | $75M | $949.0K | |
| Liabilities + Equity | $343M | $160M | $173M | $126M | |
| Shares Outstanding | 285,051,648 | 204,943,306 | 186,960,193 | 63,207,507 |
Flujo de Efectivo 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Stock-based Comp | $13M | $13M | $8M | $18M | |
| Operating Cash Flow | $-93M | $-81M | $-73M | $-88M | |
| CapEx | $738.0K | $374.0K | $4M | $21M | |
| Investing Cash Flow | $-604.0K | $-363.0K | $-7M | $-25M | |
| Stock Issued | · | · | $500.0K | · | |
| Financing Cash Flow | $275M | $77M | $136M | $52M | |
| Net Change in Cash | $181M | $-5M | $56M | $-61M | |
| Free Cash Flow | $-94M | $-82M | $-77M | · |
Rentabilidad 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Operating Margin | -1130.7% | -1097.5% | -468.8% | · | |
| Net Margin | -1115.3% | -1071.6% | -722.1% | · | |
| EBITDA Margin | -1130.7% | -1097.5% | -468.8% | · | |
| ROA | -43.3% | -53.6% | -74.6% | · | |
| ROE | -44.0% | -111.4% | -864.1% | · |
Liquidez y Solvencia 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 12.2 | 5.4 | 4.1 | · | |
| Quick Ratio | 12.0 | 5.3 | 3.9 | · | |
| Debt / Equity | 0.2 | 0.6 | 0.5 | · | |
| LT Debt / Equity | 0.2 | 0.6 | 0.5 | · | |
| Interest Coverage | · | · | -14.5 | · |
Eficiencia 1
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.1 | 0.1 | · |
Tasas de Crecimiento 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue YoY | 17.3% | -46.1% | 517.6% | · | |
| Revenue CAGR 3Y | 57.5% | · | · | · |
Valoración (TTM) 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue TTM | $10M | $8M | $15M | $3M | |
| Net Income TTM | $-109M | $-89M | $-112M | $-166M | |
| Market Cap | $1.57B | $355M | $331M | · | |
| Enterprise Value | $1.30B | $259M | $227M | · | |
| P/E | -16.2 | -4.8 | -1.8 | -0.6 | |
| P/S | 160.4 | 42.5 | 21.4 | · | |
| P/B | 6.3 | 5.0 | 4.4 | · | |
| P / Tangible Book | 6.3 | 5.0 | 4.4 | 150.5 | |
| P / Cash Flow | -16.8 | -4.4 | -4.5 | · | |
| P / FCF | -16.7 | -4.3 | -4.3 | · | |
| EV / EBITDA | -11.7 | -2.8 | -3.1 | · | |
| EV / FCF | -13.8 | -3.2 | -3.0 | · | |
| EV / Revenue | 132.8 | 31.1 | 14.7 | · | |
| Earnings Yield | -6.2% | -20.8% | -54.2% | -167.3% |
Estado de resultados 15
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $5M | $0 | $2M | $2M | $2M | $2M | $1M | $3M | $4M | $5M | $2M | $5M | |
| R&D Expense | $39M | $34M | $25M | $26M | $20M | $16M | $15M | $15M | $15M | $21M | $13M | $12M | $20M | $13M | |
| SG&A Expense | $12M | $10M | $9M | $8M | $9M | $8M | $7M | $8M | $7M | $7M | $7M | $9M | $6M | $9M | |
| Operating Expenses | $47M | $43M | $34M | $34M | $29M | $24M | $22M | $28M | $22M | $28M | $20M | $21M | $26M | $21M | |
| Operating Income | $-47M | $-43M | $-28M | $-34M | $-27M | $-21M | $-20M | $-26M | $-21M | $-24M | $-16M | $-16M | $-23M | $-17M | |
| Interest Expense | · | · | · | · | · | · | · | · | $27.0K | $29.0K | · | $1M | $1M | $1M | |
| Interest Income | $2M | $3M | $3M | $3M | $2M | $1M | $2M | $2M | $1M | $2M | $2M | $1M | · | · | |
| Other Non-op | $-88.0K | $-31.0K | $-30.0K | $-37.0K | $-237.0K | $13.0K | $-66.0K | $-81.0K | $42.0K | $-5.0K | $-23.0K | $-19.0K | $3.0K | $-8.0K | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | · | $0 | $0 | $0 | |
| Net Income | $-47M | $-42M | $-28M | $-33M | $-27M | $-22M | $-19M | $-26M | $-21M | $-24M | $48M | $-117M | $-25M | $-18M | |
| EPS (Basic) | $-0.13 | $-0.12 | $-0.08 | $-0.09 | $-0.09 | $-0.08 | $-0.07 | $-0.10 | $-0.09 | $-0.10 | $0.63 | $-0.93 | $-0.38 | $-0.28 | |
| EPS (Diluted) | $-0.13 | $-0.12 | $-0.08 | $-0.09 | $-0.09 | $-0.08 | $-0.07 | $-0.10 | $-0.09 | $-0.10 | $0.63 | $-0.93 | $-0.38 | $-0.28 | |
| Shares (Basic) | 369,044,040 | 366,632,827 | -600,892,861 | 353,309,524 | 297,988,978 | 269,306,331 | -481,760,521 | 267,824,045 | 232,821,553 | 231,249,344 | -137,084,753 | 125,700,799 | 64,244,531 | 63,260,905 | |
| Shares (Diluted) | 369,044,040 | 366,632,827 | -600,892,861 | 353,309,524 | 297,988,978 | 269,306,331 | -481,760,521 | 267,824,045 | 232,821,553 | 231,249,344 | -137,084,753 | 125,700,799 | 64,244,531 | 63,260,905 | |
| EBITDA | $-47M | $-43M | · | $-34M | $-27M | $-21M | · | $-26M | $-21M | $-24M | · | $-16M | $-23M | $-17M |
Balance general 23
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $455M | $277M | $320M | $297M | $313M | $117M | $139M | $158M | $173M | $124M | $144M | $164M | $45M | $63M | |
| Prepaid Expense | $6M | $5M | $4M | $2M | $3M | $4M | $3M | $3M | $3M | $4M | $3M | $6M | $9M | $9M | |
| Other Current Assets | $851.0K | $1M | $802.0K | $456.0K | $657.0K | $536.0K | $308.0K | $465.0K | $206.0K | $149.0K | $292.0K | $404.0K | $510.0K | $532.0K | |
| Current Assets | $461M | $282M | $325M | $300M | $316M | $121M | $142M | $162M | $178M | $131M | $150M | $172M | $54M | $72M | |
| PP&E (Net) | $2M | $6M | $7M | $7M | $7M | $7M | $7M | $8M | $11M | $11M | $11M | $11M | $14M | $15M | |
| PP&E (Gross) | $8M | $11M | $11M | $11M | $11M | $11M | $11M | $12M | $14M | $14M | $14M | $14M | $16M | $17M | |
| Accum. Depreciation | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $4M | $4M | $3M | $3M | $3M | $2M | $2M | |
| Other Non-current Assets | $106.0K | $181.0K | $183.0K | $184.0K | $186.0K | $188.0K | $217.0K | $220.0K | $288.0K | $304.0K | $304.0K | $304.0K | $304.0K | $1M | |
| Total Assets | $470M | $300M | $343M | $317M | $333M | $138M | $160M | $180M | $200M | $153M | $173M | $196M | $82M | $102M | |
| Accounts Payable | $9M | $5M | $6M | $5M | $8M | $4M | $4M | $5M | $9M | $10M | $6M | $8M | $11M | $9M | |
| Current Liabilities | $26M | $20M | $27M | $29M | $25M | $23M | $26M | $29M | $34M | $39M | $37M | $180M | $51M | $54M | |
| Capital Leases | $6M | $18M | $18M | $17M | $17M | $17M | $17M | $18M | $18M | $18M | $19M | $19M | $20M | $20M | |
| Other Non-current Liabilities | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $4M | $4M | $4M | |
| Total Liabilities | $83M | $88M | $96M | $98M | $85M | $83M | $89M | $91M | $92M | $99M | $98M | $245M | $119M | $117M | |
| Long-term Debt | · | · | · | · | · | · | · | · | · | · | · | · | $38M | $38M | |
| Total Debt | $49M | $49M | · | $51M | $41M | $42M | · | $43M | $38M | $41M | · | $39M | $38M | $38M | |
| Common Stock | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $1.0K | $1.0K | |
| Paid-in Capital | $1.19B | $965M | $958M | $904M | $900M | $681M | $678M | $675M | $664M | $591M | $588M | $512M | $407M | $404M | |
| Retained Earnings | $-800M | $-754M | $-711M | $-683M | $-651M | $-624M | $-602M | $-584M | $-558M | $-537M | $-513M | $-561M | $-444M | $-419M | |
| AOCI | $769.0K | $985.0K | $-192.0K | $-1M | $-699.0K | $-2M | $-4M | $-2M | $2M | $-251.0K | · | · | · | · | |
| Stockholders' Equity | $387M | $212M | $247M | $219M | $249M | $55M | $72M | $89M | $109M | $54M | $75M | $-49M | $-37M | $-15M | |
| Liabilities + Equity | $470M | $300M | $343M | $317M | $333M | $138M | $160M | $180M | $200M | $153M | $173M | $196M | $82M | $102M | |
| Shares Outstanding | 325,302,280 | 287,276,885 | 285,051,648 | 273,915,373 | 272,730,060 | 205,054,570 | 204,943,306 | 204,943,306 | 201,381,450 | 187,018,275 | 186,960,193 | 186,960,193 | 64,432,637 | 63,473,349 |
Flujo de Efectivo 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $6M | $6M | $4M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $2M | $2M | $2M | $2M | |
| Operating Cash Flow | $-40M | $-41M | $-27M | $-24M | $-20M | $-22M | $-18M | $-22M | $-22M | $-20M | $-16M | $-18M | $-19M | $-20M | |
| CapEx | $-1.0K | $24.0K | $250.0K | $108.0K | $2.0K | $378.0K | $-2.0K | $35.0K | $201.0K | $140.0K | $17.0K | $0 | $-48.0K | $4M | |
| Investing Cash Flow | $1.0K | $-3M | $-247.0K | $-48.0K | $62.0K | $-371.0K | $13.0K | $-35.0K | $-201.0K | $-140.0K | $-10.0K | $-3M | $48.0K | $-4M | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | $0 | · | · | · | |
| Financing Cash Flow | $217M | $711.0K | $50M | $9M | $216M | $-52.0K | $-357.0K | $7M | $70M | $-22.0K | $-4M | $141M | $377.0K | $-370.0K | |
| Net Change in Cash | $176M | $-43M | $23M | $-15M | $196M | $-22M | $-19M | $-15M | $49M | $-20M | $-20M | $119M | $-18M | $-24M | |
| Free Cash Flow | · | $-41M | · | · | · | · | · | · | · | $-20M | · | · | · | $-24M |
Rentabilidad 5
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | -1347.1% | -930.5% | · | -1448.4% | -1915.4% | -713.3% | · | -342.4% | -976.4% | -351.9% | |
| Net Margin | · | · | · | · | -1353.6% | -935.2% | · | -1427.5% | -1882.0% | -705.4% | · | -2467.1% | -1027.1% | -374.5% | |
| EBITDA Margin | · | · | · | · | -1347.1% | -930.5% | · | -1448.4% | -1915.4% | -713.3% | · | -342.4% | -976.4% | -351.9% | |
| ROA | -11.6% | -19.3% | · | -13.2% | -10.1% | -14.8% | · | -13.6% | -14.8% | -18.9% | · | -76.2% | -22.0% | -13.2% | |
| ROE | -14.7% | -31.8% | · | -21.3% | -15.0% | -39.5% | · | -128.6% | -58.3% | -123.7% | · | 616.4% | 1117.1% | -98.5% |
Liquidez y Solvencia 5
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 17.8 | 14.0 | · | 10.5 | 12.5 | 5.4 | · | 5.5 | 5.2 | 3.4 | · | 1.0 | 1.1 | 1.3 | |
| Quick Ratio | 17.5 | 13.8 | · | 10.4 | 12.3 | 5.2 | · | 5.4 | 5.1 | 3.2 | · | 0.9 | 0.9 | 1.2 | |
| Debt / Equity | 0.1 | 0.2 | · | 0.2 | 0.2 | 0.8 | · | 0.5 | 0.3 | 0.8 | · | -0.8 | -1.0 | -2.6 | |
| LT Debt / Equity | 0.1 | 0.2 | · | 0.2 | 0.2 | 0.8 | · | 0.5 | 0.3 | 0.8 | · | -0.8 | -1.0 | -2.6 | |
| Interest Coverage | · | · | · | · | · | · | · | · | -788.9 | -839.0 | · | -11.0 | -16.2 | -12.1 |
Eficiencia 1
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 |
Valoración (TTM) 14
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $2M | $4M | · | $6M | $7M | $9M | · | $11M | $12M | $15M | · | · | · | · | |
| Net Income TTM | $-149M | $-124M | · | $-107M | $-95M | $-92M | · | $-188M | $-187M | $-183M | · | $-186M | $-103M | $-129M | |
| Market Cap | $2.22B | $1.28B | · | $896M | $630M | $285M | · | $412M | $451M | $537M | · | $591M | $43M | $51M | |
| Enterprise Value | $1.81B | $1.06B | · | $649M | $358M | $211M | · | $297M | $316M | $453M | · | $465M | $36M | $25M | |
| P/E | -15.8 | -11.8 | · | -9.1 | -6.4 | -3.8 | · | -1.6 | -1.5 | -1.7 | · | -1.4 | -0.3 | -0.3 | |
| P/S | 1115.5 | 299.5 | · | 147.4 | 87.6 | 33.1 | · | 37.3 | 38.7 | 35.2 | · | · | · | · | |
| P/B | 5.7 | 6.1 | · | 4.1 | 2.5 | 5.2 | · | 4.6 | 4.1 | 10.0 | · | -12.0 | -1.1 | -3.4 | |
| P / Tangible Book | 5.7 | 6.1 | · | 4.1 | 2.5 | 5.2 | · | 4.6 | 4.1 | 10.0 | · | · | · | · | |
| P / Cash Flow | · | -31.4 | · | · | · | -12.9 | · | · | · | -27.1 | · | · | · | -2.5 | |
| P / FCF | · | -31.4 | · | · | · | · | · | · | · | -26.9 | · | · | · | -2.1 | |
| EV / EBITDA | -38.2 | -24.3 | · | -19.1 | -13.4 | -9.8 | · | -11.5 | -14.8 | -18.6 | · | -28.6 | -1.5 | -1.5 | |
| EV / FCF | · | -25.8 | · | · | · | · | · | · | · | -22.7 | · | · | · | -1.1 | |
| EV / Revenue | 911.0 | 246.4 | · | 106.8 | 49.8 | 24.5 | · | 26.9 | 27.1 | 29.7 | · | · | · | · | |
| Earnings Yield | -6.3% | -8.5% | · | -11.0% | -15.6% | -26.6% | · | -60.7% | -67.0% | -58.9% | · | -70.9% | -326.8% | -388.5% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $10M | $8M | $15M | $3M | — |
| Margen Operativo % | -1130.7% | -1097.5% | -468.8% | — | — |
| Beneficio neto | $-109M | $-89M | $-112M | $-166M | $-175M |
| EPS Diluido | $-0.34 | $-0.36 | $-0.96 | $-3.78 | $-4.64 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Deuda / Patrimonio | 0.2 | 0.6 | 0.5 | — | 0.4 |
| Ratio corriente | 12.2 | 5.4 | 4.1 | — | 3.1 |
| Ratio Rápido | 12.0 | 5.3 | 3.9 | — | 2.9 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-94M | $-82M | $-77M | — | $-132M |
Últimas noticias Noticias recientes que mencionan a esta empresa
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Propietarios institucionales (13F) 224 declarantes · $1.7B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 48 (+20 vs trimestre anterior) | 23 (-7 vs trimestre anterior) | 90 (+26 vs trimestre anterior) | 42 (-13 vs trimestre anterior) | +44.7M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | $162 683 327 | 23 888 888 | 9,61% | Acciones |
| RA CAPITAL MANAGEMENT, L.P. | $160 413 963 | 23 555 648 | 9,48% | Acciones |
| Vestal Point Capital, LP | $132 216 150 | 19 415 000 | 7,81% | Acciones |
| GOLDMAN SACHS GROUP INC | $92 490 887 | 13 581 628 | 5,46% | Acciones |
| RTW INVESTMENTS, LP | $92 345 357 | 13 560 258 | 5,46% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $84 979 232 | 12 478 595 | 5,02% | Acciones |
| STATE STREET CORP | $77 783 275 | 11 421 920 | 4,59% | Acciones |
| Siren, L.L.C. | $67 055 203 | 9 846 579 | 3,96% | Acciones |
| Octagon Capital Advisors LP | $66 010 992 | 9 693 244 | 3,90% | Acciones |
| VANGUARD GROUP INC | $63 339 386 | 11 516 252 | 3,74% | Acciones |
| FMR LLC | $53 647 634 | 7 877 773 | 3,17% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $38 279 203 | 5 619 701 | 2,26% | Acciones |
| Polar Capital Holdings Plc | $34 847 676 | 5 117 133 | 2,06% | Acciones |
| MPM BIOIMPACT LLC | $30 645 000 | 4 500 000 | 1,81% | Acciones |
| BAKER BROS. ADVISORS LP | $27 272 388 | 4 004 756 | 1,61% | Acciones |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $26 460 262 | 3 885 501 | 1,56% | Acciones |
| GordonMD Global Investments LP | $24 501 508 | 723 185 | 1,45% | Acciones |
| Casdin Capital, LLC | $22 132 500 | 3 250 000 | 1,31% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $21 383 461 | 3 140 009 | 1,26% | Acciones |
| ADAR1 Capital Management, LLC | $20 705 573 | 3 040 466 | 1,22% | Acciones |
| Pictet Asset Management Holding SA | $18 868 474 | 2 770 701 | 1,11% | Acciones |
| Aberdeen Group plc | $15 847 905 | 2 327 152 | 0,94% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $15 761 752 | 2 314 501 | 0,93% | Acciones |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $15 322 500 | 2 250 000 | 0,91% | Acciones |
| NORGES BANK | $15 210 816 | 2 233 600 | 0,90% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $14 986 733 | 2 200 695 | 0,89% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $14 483 767 | 2 126 838 | 0,86% | Acciones |
| ORBIMED ADVISORS LLC | $13 620 000 | 2 000 000 | 0,80% | Acciones |
| RICE HALL JAMES & ASSOCIATES, LLC | $13 567 079 | 1 992 229 | 0,80% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $12 914 988 | 1 896 474 | 0,76% | Acciones |
| B Group, Inc. | $12 261 786 | 1 800 556 | 0,72% | Acciones |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD | $12 099 000 | 3 700 000 | 0,71% | Acciones |
| Affinity Asset Advisors, LLC | $11 917 500 | 1 750 000 | 0,70% | Acciones |
| BARCLAYS PLC | $11 020 670 | 1 618 307 | 0,65% | Acciones |
| HEIGHTS CAPITAL MANAGEMENT, INC | $10 215 000 | 1 500 000 | 0,60% | Acciones |
| Seven Fleet Capital Management LP | $9 940 323 | 1 504 400 | 0,59% | Acciones |
| Palo Alto Investors LP | $9 475 311 | 1 391 382 | 0,56% | Acciones |
| Granahan Investment Management, LLC | $8 888 255 | 1 305 177 | 0,53% | Acciones |
| BANK OF AMERICA CORP /DE/ | $8 103 178 | 1 189 894 | 0,48% | Acciones |
| CITADEL ADVISORS LLC | $7 471 292 | 1 097 106 | 0,44% | Acciones |
| Quantum Private Wealth, LLC | $5 529 903 | 812 027 | 0,33% | Acciones |
| FIRST TRUST ADVISORS LP | $5 387 860 | 791 169 | 0,32% | Acciones |
| Sands Capital Alternatives, LLC | $4 936 385 | 724 873 | 0,29% | Acciones |
| D. E. Shaw & Co., Inc. | $4 871 997 | 715 418 | 0,29% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $4 358 638 | 640 035 | 0,26% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $4 020 535 | 590 387 | 0,24% | Acciones |
| AFFINITY WEALTH MANAGEMENT LLC | $3 928 062 | 576 808 | 0,23% | Acciones |
| Squarepoint Ops LLC | $3 876 722 | 569 269 | 0,23% | Acciones |
| ACUTA CAPITAL PARTNERS, LLC | $3 825 912 | 561 808 | 0,23% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3 799 980 | 558 000 | 0,22% | Opción de compra |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3 765 930 | 553 000 | 0,22% | Acciones |
| DIADEMA PARTNERS LP | $3 559 035 | 522 619 | 0,21% | Acciones |
| Woodline Partners LP | $3 499 169 | 513 828 | 0,21% | Acciones |
| Holocene Advisors, LP | $3 473 100 | 510 000 | 0,21% | Acciones |
| Ghisallo Capital Management LLC | $3 439 050 | 505 000 | 0,20% | Acciones |
| Burkehill Global Management, LP | $3 405 000 | 500 000 | 0,20% | Acciones |
| POLEN CAPITAL MANAGEMENT LLC | $3 331 581 | 489 219 | 0,20% | Acciones |
| Trexquant Investment LP | $2 584 919 | 379 577 | 0,15% | Acciones |
| Swiss National Bank | $2 512 890 | 369 000 | 0,15% | Acciones |
| MOORE CAPITAL MANAGEMENT, LP | $2 440 527 | 358 374 | 0,14% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $2 371 603 | 348 253 | 0,14% | Acciones |
| Jefferies Financial Group Inc. | $2 239 128 | 328 800 | 0,13% | Acciones |
| RHUMBLINE ADVISERS | $2 042 820 | 299 975 | 0,12% | Acciones |
| CITIGROUP INC | $1 995 800 | 293 069 | 0,12% | Acciones |
| ALPS ADVISORS INC | $1 978 598 | 290 543 | 0,12% | Acciones |
| Ensign Peak Advisors, Inc | $1 790 322 | 262 896 | 0,11% | Acciones |
| Qube Research & Technologies Ltd | $1 767 910 | 259 605 | 0,10% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $1 702 500 | 250 000 | 0,10% | Acciones |
| Bank of New York Mellon Corp | $1 660 258 | 243 797 | 0,10% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $1 598 416 | 234 716 | 0,09% | Acciones |
| WELLS FARGO & COMPANY/MN | $1 489 565 | 218 732 | 0,09% | Acciones |
| ORACLE INVESTMENT MANAGEMENT INC | $1 457 500 | 265 000 | 0,09% | Acciones |
| BlackRock, Inc. | $1 411 468 | 207 264 | 0,08% | Acciones |
| Monashee Investment Management LLC | $1 362 000 | 200 000 | 0,08% | Acciones |
| Privium Fund Management B.V. | $1 354 509 | 198 900 | 0,08% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $1 345 506 | 197 578 | 0,08% | Acciones |
| Chicago Partners Investment Group LLC | $1 296 283 | 222 347 | 0,08% | Acciones |
| Balyasny Asset Management L.P. | $1 289 351 | 189 332 | 0,08% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 205 976 | 177 089 | 0,07% | Acciones |
| MORGAN STANLEY | $1 204 212 | 176 830 | 0,07% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $1 107 130 | 247 680 | 0,07% | Acciones |
| WEXFORD CAPITAL LP | $1 094 054 | 160 654 | 0,06% | Acciones |
| JANE STREET GROUP, LLC | $1 054 045 | 154 779 | 0,06% | Acciones |
| Rafferty Asset Management, LLC | $1 053 548 | 154 706 | 0,06% | Acciones |
| Palumbo Wealth Management LLC | $1 015 869 | 149 173 | 0,06% | Acciones |
| MetLife Investment Management, LLC | $959 161 | 140 846 | 0,06% | Acciones |
| Vanguard Global Advisers, LLC | $911 321 | 133 821 | 0,05% | Acciones |
| Persistent Asset Partners Ltd | $908 529 | 133 411 | 0,05% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $903 101 | 132 614 | 0,05% | Acciones |
| Mariner, LLC | $793 923 | 116 582 | 0,05% | Acciones |
| CITADEL ADVISORS LLC | $783 150 | 115 000 | 0,05% | Opción de compra |
| TWO SIGMA ADVISERS, LP | $767 696 | 139 581 | 0,05% | Acciones |
| Aquatic Capital Management LLC | $736 896 | 108 208 | 0,04% | Acciones |
| Engineers Gate Manager LP | $709 139 | 104 132 | 0,04% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $708 887 | 104 095 | 0,04% | Acciones |
| XTX Topco Ltd | $689 138 | 101 195 | 0,04% | Acciones |
| PRELUDE CAPITAL MANAGEMENT, LLC | $669 736 | 98 346 | 0,04% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $663 294 | 97 400 | 0,04% | Opción de venta |
| Invesco Ltd. | $650 055 | 95 456 | 0,04% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $612 091 | 136 933 | 0,04% | Acciones |
Informantes de la empresa 11 insiders · 4 directivos · 7 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Sean P. Nolan | Chief Executive Officer | 2 de enero de 2024 A | 1 185 858 | 0 | 0 | $0 |
| Kamran Alam | Chief Financial Officer | 2 de enero de 2024 A | 842 225 | 0 | 0 | $0 |
| Sukumar Nagendran | President and Head of R&D | 2 de enero de 2024 A | 897 843 | 0 | 0 | $0 |
| Suyash Prasad | CMO and Head of R&D | 6 de julio de 2022 S | 530 589 | 0 | 0 | $0 |
| Alison S Long | Consejero | 1 de noviembre de 2023 A | — | 0 | 0 | $0 |
| John A Stalfort III | Consejero | 16 de agosto de 2023 G | 1 049 381 | 0 | 0 | $0 |
| Phillip B. Donenberg | Consejero | 16 de agosto de 2023 P | 114 111 | 0 | 0 | $0 |
| Kathleen Reape | Consejero | 22 de junio de 2023 A | — | 0 | 0 | $0 |
| Laura Sepp-Lorenzino | Consejero | 22 de junio de 2023 A | — | 0 | 0 | $0 |
| Paul B Manning | Propietario del 10% | 17 de noviembre de 2023 P | 16 566 667 | 0 | 0 | $0 |
| R.A. Session II | Propietario del 10% | 13 de julio de 2023 S | 8 871 747 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 4 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Paul B Manning, The Paul B. Manning Revocable Trust dated May 10, 2000, The PBM 2023 Grantor Retained Annuity Trust, The PBM 2025 Grantor Retained Annuity Trust, BKB Growth Investments, LLC, BKB G2 Investments, LLC | 3 de junio de 2025 | 9,80% | Enmienda | — | SEC |
| Paul B. Manning, The Paul B. Manning Revocable Trust dated May 10, 2000, The PBM 2023 Grantor Retained Annuity Trust, BKB Growth Investments, LLC, BKB G2 Investments, LLC ×3 presentaciones | 21 de agosto de 2023 | — | Presentación inicial | — | SEC |
| Astellas Pharma Inc., Astellas US Holding, Inc., Astellas Gene Therapies, Inc. (f/k/a Audentes Therapeutics, Inc.) ×2 presentaciones | 18 de agosto de 2023 | — | Presentación inicial | — | SEC |
| RA Session II, RA Session II, as Trustee of the Session 2020 Annuity Trust I, RA Session II, as Trustee of the Session 2020 Annuity Trust II | 5 de octubre de 2020 | — | Presentación inicial | Inversión pasiva | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 44 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| IBRN · iShares Trust | 1,53% | 18 665 SH | 8 de agosto de 2026 | Diario |
| SBIO · ALPS ETF Trust | 1,02% | 282 348 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,82% | 47 669 NS | 30 de abril de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,40% | 322 791 NS | 30 de abril de 2026 | N-PORT |
| FYC · First Trust Exchange-Traded AlphaDE… | 0,32% | 522 481 NS | 30 de abril de 2026 | N-PORT |
| ESSC · Strategy Shares | 0,18% | 7 298 NS | 30 de abril de 2026 | N-PORT |
| IBB · iShares Trust | 0,13% | 1 949 477 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,13% | 15 639 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,11% | 332 492 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,10% | 257 044 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,09% | 2 159 516 SH | 8 de agosto de 2026 | Diario |
| FYX · First Trust Exchange-Traded AlphaDE… | 0,08% | 154 894 NS | 30 de abril de 2026 | N-PORT |
| BIB · ProShares Trust | 0,08% | 10 128 NS | 31 de mayo de 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,06% | 48 717 NS | 30 de abril de 2026 | N-PORT |
| GINN · Goldman Sachs ETF Trust | 0,06% | 23 348 NS | 31 de mayo de 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,05% | 1 379 816 SH | 8 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,05% | 6 118 574 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,04% | 95 596 NS | 30 de abril de 2026 | N-PORT |
| ISCG · iShares Trust | 0,04% | 66 429 SH | 8 de agosto de 2026 | Diario |
| GSSC · Goldman Sachs ETF Trust | 0,04% | 64 980 NS | 31 de mayo de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,03% | 10 394 NS | 31 de mayo de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,03% | 1 069 955 NS | 31 de mayo de 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,03% | 117 196 SH | 8 de agosto de 2026 | Diario |
| TEXN · iShares Trust | 0,02% | 631 SH | 8 de agosto de 2026 | Diario |
| ISCB · iShares Trust | 0,02% | 9 303 SH | 8 de agosto de 2026 | Diario |
| VXF · VANGUARD INDEX FUNDS | 0,02% | 3 043 718 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,02% | 552 457 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,02% | 8 129 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 62 485 NS | 30 de abril de 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 8 221 NS | 31 de mayo de 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 8 217 SH | 8 de agosto de 2026 | Diario |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 8 504 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 206 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 92 844 NS | 31 de mayo de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,00% | 78 390 NS | 30 de abril de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 332 315 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,00% | 69 995 SH | 8 de agosto de 2026 | Diario |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 131 780 NS | 31 de mayo de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 4 760 NS | 30 de abril de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 3 045 NS | 30 de abril de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 5 870 NS | 30 de abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 10 179 NS | 30 de abril de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 9 141 487 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 20 636 SH | 8 de agosto de 2026 | Diario |