AGIO — Détenteurs institutionnels (13F)

262 déclarants · $2.7B total · Au 30 septembre 2026

Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.

Institution Valeur Actions % de 13F suivies Type
BlackRock, Inc. $239 582 050 6 455 997 8,88% Actions
FARALLON CAPITAL MANAGEMENT, L.L.C. $219 594 714 5 917 400 8,14% Actions
VANGUARD GROUP INC $152 278 288 5 594 353 5,64% Actions
STATE STREET CORP $131 144 972 3 533 633 4,86% Actions
Lynx1 Capital Management LP $126 505 652 3 408 937 4,69% Actions
D. E. Shaw & Co., Inc. $115 300 956 3 107 005 4,27% Actions
VANGUARD PORTFOLIO MANAGEMENT LLC $107 552 091 2 898 197 3,98% Actions
ARMISTICE CAPITAL, LLC $104 279 100 2 810 000 3,86% Option d'achat
VANGUARD CAPITAL MANAGEMENT LLC $99 523 268 2 681 845 3,69% Actions
ARMISTICE CAPITAL, LLC $89 064 000 2 400 000 3,30% Actions
Erste Asset Management GmbH $81 972 396 2 154 900 3,04% Actions
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $78 332 000 2 110 809 2,90% Actions
GEODE CAPITAL MANAGEMENT, LLC $58 433 490 1 574 268 2,17% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $51 046 957 1 375 558 1,89% Actions
ADAR1 Capital Management, LLC $47 799 647 1 288 053 1,77% Actions
BNP PARIBAS ASSET MANAGEMENT Holding S.A. $47 502 433 1 280 044 1,76% Actions
DIMENSIONAL FUND ADVISORS LP $46 345 467 1 248 738 1,72% Actions
GOLDMAN SACHS GROUP INC $42 711 087 1 150 932 1,58% Actions
UBS Group AG $36 584 189 985 831 1,36% Actions
MORGAN STANLEY $35 746 487 963 256 1,32% Actions
Nuveen, LLC $32 417 811 873 560 1,20% Actions
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $30 078 768 810 530 1,11% Actions
Foresite Capital Management VI LLC $29 131 350 785 000 1,08% Actions
CITADEL ADVISORS LLC $27 190 015 732 687 1,01% Actions
AQR CAPITAL MANAGEMENT LLC $25 395 858 684 340 0,94% Actions
Parkman Healthcare Partners LLC $24 828 297 669 046 0,92% Actions
SCS Capital Management LLC $22 742 864 612 850 0,84% Actions
Qube Research & Technologies Ltd $22 178 346 597 638 0,82% Actions
NORTHERN TRUST CORP $20 585 250 554 709 0,76% Actions
Defilade Capital Management, L.P. $20 293 529 546 848 0,75% Actions
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $19 969 930 538 128 0,74% Actions
TWO SIGMA INVESTMENTS, LP $19 905 062 536 380 0,74% Actions
Rock Springs Capital Management LP $19 763 413 532 563 0,73% Actions
Schonfeld Strategic Advisors LLC $19 300 279 520 083 0,72% Actions
BANK OF AMERICA CORP /DE/ $18 847 034 507 869 0,70% Actions
Point72 Asset Management, L.P. $18 790 426 506 344 0,70% Actions
JANE STREET GROUP, LLC $18 280 312 492 598 0,68% Actions
Legal & General Group Plc $16 132 422 434 719 0,60% Actions
VANGUARD FIDUCIARY TRUST CO $14 690 661 395 868 0,54% Actions
PANAGORA ASSET MANAGEMENT INC $13 876 579 373 931 0,51% Actions
KENNEDY CAPITAL MANAGEMENT LLC $13 850 565 373 230 0,51% Actions
JPMORGAN CHASE & CO $13 783 528 359 756 0,51% Actions
Connor, Clark & Lunn Investment Management Ltd. $13 342 901 359 550 0,49% Actions
Squarepoint Ops LLC $11 917 431 321 138 0,44% Actions
Ensign Peak Advisors, Inc $11 045 049 297 630 0,41% Actions
BNP PARIBAS FINANCIAL MARKETS $9 996 803 269 383 0,37% Actions
ALGERT GLOBAL LLC $9 203 540 248 007 0,34% Actions
JANE STREET GROUP, LLC $7 974 939 214 900 0,30% Option de vente
Palo Alto Investors LP $7 926 733 213 601 0,29% Actions
Tetragon Partners GP Ltd $7 629 037 205 579 0,28% Actions
Bank of New York Mellon Corp $7 373 215 198 685 0,27% Actions
AXA Investment Managers S.A. $7 131 875 177 675 0,26% Actions
Cutter Capital Management, LP $6 895 755 235 350 0,26% Actions
Jump Financial, LLC $6 782 706 182 773 0,25% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $6 334 677 170 700 0,23% Option d'achat
Invesco Ltd. $6 240 157 168 153 0,23% Actions
FIRST TRUST ADVISORS LP $6 144 933 165 587 0,23% Actions
Ishara Investments LP $6 086 040 164 000 0,23% Actions
GROUP ONE TRADING LLC $5 640 497 151 994 0,21% Actions
BOOTHBAY FUND MANAGEMENT, LLC $5 562 269 149 886 0,21% Actions
MARSHALL WACE, LLP $5 150 868 138 800 0,19% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5 080 359 136 900 0,19% Option de vente
AMERICAN CENTURY COMPANIES INC $4 991 740 134 512 0,18% Actions
Man Group plc $4 618 933 124 466 0,17% Actions
ArrowMark Colorado Holdings LLC $4 368 367 117 714 0,16% Actions
Pictet Asset Management Holding SA $4 247 606 111 861 0,16% Actions
Swiss National Bank $4 143 703 111 660 0,15% Actions
CAPITAL FUND MANAGEMENT S.A. $3 862 408 104 080 0,14% Actions
Assenagon Asset Management S.A. $3 857 770 103 955 0,14% Actions
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $3 744 272 110 679 0,14% Actions
Universal- Beteiligungs- und Servicegesellschaft mbH $3 700 831 99 726 0,14% Actions
Knott David M Jr $3 527 602 95 058 0,13% Actions
Trexquant Investment LP $3 471 232 93 539 0,13% Actions
CITADEL ADVISORS LLC $3 402 987 91 700 0,13% Option d'achat
Jain Global LLC $3 401 020 91 647 0,13% Actions
Caligan Partners LP $3 339 900 90 000 0,12% Option d'achat
CITIGROUP INC $3 308 987 89 167 0,12% Actions
CITADEL ADVISORS LLC $3 295 368 88 800 0,12% Option de vente
RHUMBLINE ADVISERS $2 948 045 79 441 0,11% Actions
Campbell & CO Investment Adviser LLC $2 712 555 73 095 0,10% Actions
Exome Asset Management LLC $2 616 255 70 500 0,10% Actions
Edgestream Partners, L.P. $2 604 936 70 195 0,10% Actions
Russell Investments Group, Ltd. $2 481 023 66 856 0,09% Actions
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $2 478 800 66 796 0,09% Actions
TUDOR INVESTMENT CORP ET AL $2 441 059 65 779 0,09% Actions
TWO SIGMA ADVISERS, LP $2 319 144 85 200 0,09% Actions
DEUTSCHE BANK AG\ $2 309 281 62 228 0,09% Actions
ALPS ADVISORS INC $2 228 789 60 059 0,08% Actions
Seven Fleet Capital Management LP $2 111 559 56 900 0,08% Actions
ALLIANCEBERNSTEIN L.P. $2 092 859 61 864 0,08% Actions
Rafferty Asset Management, LLC $2 062 574 55 580 0,08% Actions
Engineers Gate Manager LP $2 000 674 53 912 0,07% Actions
WELLS FARGO & COMPANY/MN $1 975 736 53 240 0,07% Actions
VANGUARD ASSET MANAGEMENT, Ltd $1 931 576 52 050 0,07% Actions
XTX Topco Ltd $1 869 082 50 366 0,07% Actions
Caption Management, LLC $1 855 500 50 000 0,07% Option d'achat
Tetragon Partners GP Ltd $1 855 500 50 000 0,07% Option d'achat
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main $1 846 742 49 764 0,07% Actions
BARCLAYS PLC $1 792 412 48 300 0,07% Actions
Quantinno Capital Management LP $1 614 805 43 514 0,06% Actions
MARTINGALE ASSET MANAGEMENT L P $1 596 064 43 009 0,06% Actions
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1 544 400 41 455 0,06% Actions
IEQ CAPITAL, LLC $1 499 392 40 404 0,06% Actions
Kodai Capital Management LP $1 485 276 50 692 0,06% Actions
Virtus Investment Advisers, LLC $1 464 843 39 473 0,05% Actions
Caption Management, LLC $1 456 530 39 249 0,05% Actions
JANE STREET GROUP, LLC $1 451 001 39 100 0,05% Option d'achat
FMR LLC $1 449 962 39 072 0,05% Actions
Aquatic Capital Management LLC $1 433 448 38 627 0,05% Actions
MANUFACTURERS LIFE INSURANCE COMPANY, THE $1 400 049 37 727 0,05% Actions
SEI INVESTMENTS CO $1 302 150 35 089 0,05% Actions
EDGEWOOD MANAGEMENT LLC $1 298 850 35 000 0,05% Actions
MetLife Investment Management, LLC $1 279 182 34 470 0,05% Actions
CITIGROUP INC $1 224 630 33 000 0,05% Option d'achat
CITIGROUP INC $1 224 630 33 000 0,05% Option de vente
STATE OF WISCONSIN INVESTMENT BOARD $1 196 241 32 235 0,04% Actions
Bridgefront Capital, LLC $1 154 010 31 097 0,04% Actions
Mariner, LLC $1 081 528 29 139 0,04% Actions
PROFUND ADVISORS LLC $1 048 729 28 260 0,04% Actions
Quadrature Capital Ltd $1 043 199 28 111 0,04% Actions
VIRGINIA RETIREMENT SYSTEMS ET Al $1 030 211 27 761 0,04% Actions
AXQ CAPITAL, LP $1 026 314 27 656 0,04% Actions
OAK RIDGE INVESTMENTS LLC $951 834 25 649 0,04% Actions
BOOTHBAY FUND MANAGEMENT, LLC $950 016 25 600 0,04% Option d'achat
Coppell Advisory Solutions LLC $909 940 59 0,03% Actions
DIVERSIFIED TRUST CO $888 710 23 948 0,03% Actions
Zurcher Kantonalbank (Zurich Cantonalbank) $876 538 23 620 0,03% Actions
Vanguard Global Advisers, LLC $865 294 23 317 0,03% Actions
JACOBS LEVY EQUITY MANAGEMENT, INC $851 229 22 938 0,03% Actions
CenterBook Partners LP $812 152 21 885 0,03% Actions
JANUS HENDERSON GROUP PLC $804 696 23 797 0,03% Actions
Creative Planning $801 724 21 604 0,03% Actions
MERCER GLOBAL ADVISORS INC /ADV $790 257 21 295 0,03% Actions
WELLINGTON MANAGEMENT GROUP LLP $774 671 20 875 0,03% Actions
Headlands Technologies LLC $772 074 20 805 0,03% Actions
NEW YORK STATE COMMON RETIREMENT FUND $770 700 20 768 0,03% Actions
Cerity Partners LLC $750 699 20 229 0,03% Actions
Quarry LP $747 655 20 147 0,03% Actions
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $740 450 17 959 0,03% Actions
LOS ANGELES CAPITAL MANAGEMENT LLC $669 020 18 028 0,02% Actions
State of New Jersey Common Pension Fund D $667 906 17 998 0,02% Actions
Police & Firemen's Retirement System of New Jersey $647 347 17 444 0,02% Actions
CANADA PENSION PLAN INVESTMENT BOARD $612 315 16 500 0,02% Actions
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $588 082 15 847 0,02% Actions
FOX RUN MANAGEMENT, L.L.C. $579 732 15 622 0,02% Actions
ARIZONA STATE RETIREMENT SYSTEM $569 972 15 359 0,02% Actions
TD Asset Management Inc $559 841 15 086 0,02% Actions
Rockefeller Capital Management L.P. $554 238 14 935 0,02% Actions
AlphaCentric Advisors LLC $525 960 14 173 0,02% Actions
Atria Investments, Inc $520 765 14 033 0,02% Actions
Vanguard Investments Australia, Ltd. $502 358 13 537 0,02% Actions
Inspire Investing, LLC $498 654 14 740 0,02% Actions
INTECH INVESTMENT MANAGEMENT LLC $477 160 12 858 0,02% Actions
COMMERCE BANK $461 538 12 437 0,02% Actions
WOLVERINE TRADING, LLC $447 678 11 400 0,02% Option d'achat
ENVESTNET ASSET MANAGEMENT INC $447 435 12 057 0,02% Actions
KLP KAPITALFORVALTNING AS $437 898 11 800 0,02% Actions
CAPTRUST FINANCIAL ADVISORS $421 236 11 351 0,02% Actions
VOYA INVESTMENT MANAGEMENT LLC $421 199 11 350 0,02% Actions
Gallagher Fiduciary Advisors, LLC $411 717 11 095 0,02% Actions
ROYAL BANK OF CANADA $388 000 10 429 0,01% Actions
Toroso Investments, LLC $387 803 14 247 0,01% Actions
PRUDENTIAL FINANCIAL INC $369 430 9 955 0,01% Actions
Hudson Bay Capital Management LP $359 967 9 700 0,01% Actions
ProShare Advisors LLC $359 745 9 694 0,01% Actions
ALLSTATE CORP $351 988 9 485 0,01% Actions
China Universal Asset Management Co., Ltd. $351 246 9 465 0,01% Actions
Brevan Howard Capital Management LP $344 752 9 290 0,01% Actions
CAPSTONE INVESTMENT ADVISORS, LLC $341 264 9 196 0,01% Actions
AlphaQuest LLC $325 633 11 963 0,01% Actions
Fiduciary Trust Co $306 158 8 250 0,01% Actions
HSBC HOLDINGS PLC $293 014 7 717 0,01% Actions
E Fund Management Co., Ltd. $290 831 7 837 0,01% Actions
JONES FINANCIAL COMPANIES LLLP $289 101 7 628 0,01% Actions
Financiere des Professionnels - Fonds d'investissement inc. $278 511 7 505 0,01% Actions
PDT Partners, LLC $278 325 7 500 0,01% Actions
Savvy Advisors, Inc. $252 125 6 794 0,01% Actions
Cubist Systematic Strategies, LLC $251 438 6 264 0,01% Actions
TEACHER RETIREMENT SYSTEM OF TEXAS $240 287 6 475 0,01% Actions
VICTORY CAPITAL MANAGEMENT INC $239 026 6 441 0,01% Actions
Vanguard Personalized Indexing Management, LLC $229 043 6 172 0,01% Actions
PNC Financial Services Group, Inc. $216 573 5 836 0,01% Actions
XPONANCE LLC $213 642 5 757 0,01% Actions
Merit Financial Group, LLC $206 183 5 556 0,01% Actions
Inscription Capital, LLC $205 589 5 540 0,01% Actions
Arax Advisory Partners $199 504 5 376 0,01% Actions
Ameritas Investment Partners, Inc. $199 206 5 368 0,01% Actions
Eurizon Capital SGR S.p.A. $100 784 2 647 0,00% Actions
Mirae Asset Global Investments Co., Ltd. $98 713 2 660 0,00% Actions
Tower Research Capital LLC (TRC) $76 224 2 054 0,00% Actions
Allworth Financial LP $73 144 1 971 0,00% Actions
Versant Capital Management, Inc $66 533 2 001 0,00% Actions
OSAIC HOLDINGS, INC. $59 079 1 592 0,00% Actions
Bayforest Capital Ltd $55 368 1 492 0,00% Actions
NISA INVESTMENT ADVISORS, LLC $50 395 1 358 0,00% Actions
ASSETMARK, INC $48 874 1 317 0,00% Actions
GF FUND MANAGEMENT CO. LTD. $46 091 1 242 0,00% Actions
GW&K Investment Management, LLC $44 777 1 206 615 0,00% Actions
Quantbot Technologies LP $43 493 1 172 0,00% Actions
CWM, LLC $43 336 1 281 0,00% Actions
Sterling Capital Management LLC $42 157 1 136 0,00% Actions
Essential Partners LLC $20 670 557 0,00% Actions
US BANCORP \DE\ $20 114 542 0,00% Actions
GAMMA Investing LLC $19 965 538 0,00% Actions
EverSource Wealth Advisors, LLC $19 855 535 0,00% Actions
Kemnay Advisory Services Inc. $19 780 533 0,00% Actions
Farther Finance Advisors, LLC $18 077 484 0,00% Actions
FTB Advisors, Inc. $17 395 523 0,00% Actions
CITY HOLDING CO $16 910 500 0,00% Actions
Smartleaf Asset Management LLC $16 129 424 0,00% Actions
ROTHSCHILD INVESTMENT LLC $14 918 402 0,00% Actions
SIGNATUREFD, LLC $14 807 399 0,00% Actions
FIRST HORIZON CORP $13 174 355 0,00% Actions
True Wealth Design, LLC $11 356 306 0,00% Actions
FIFTH THIRD BANCORP $10 447 281 0,00% Actions
THURSTON, SPRINGER, MILLER, HERD & TITAK, INC. $8 943 241 0,00% Actions
Bell Investment Advisors, Inc $8 796 237 0,00% Actions
IFP Advisors, Inc $8 647 233 0,00% Actions
PRICE T ROWE ASSOCIATES INC /MD/ $8 127 218 966 0,00% Actions
Lindbrook Capital, LLC $7 530 257 0,00% Actions
Concord Wealth Partners $7 422 200 0,00% Actions
Hillsdale Investment Management Inc. $7 422 200 0,00% Actions
HRT FINANCIAL LP $5 965 160 759 0,00% Actions
COMERICA BANK $5 703 209 0,00% Actions
SJS Investment Consulting Inc. $4 862 131 0,00% Actions
Keating Financial Advisory Services, Inc. $4 602 124 0,00% Actions
Hurley Capital, LLC $4 453 120 0,00% Actions
Triumph Capital Management $3 711 100 0,00% Actions
Private Wealth Management Group, LLC $3 081 83 0,00% Actions
JPL Wealth Management, LLC $2 970 80 0,00% Actions
Wealth Enhancement Trust Services, Inc. $2 857 77 0,00% Actions
Larson Financial Group LLC $2 449 66 0,00% Actions
Clearstead Advisors, LLC $2 339 63 0,00% Actions
HARBOR CAPITAL ADVISORS, INC. $1 727 46 550 0,00% Actions
Pinnacle Wealth Planning Services, Inc. $1 484 40 0,00% Actions
ZIONS BANCORPORATION, NATIONAL ASSOCIATION /UT/ $1 410 38 0,00% Actions
SG Americas Securities, LLC $1 275 34 348 0,00% Actions
SBI Securities Co., Ltd. $1 188 32 0,00% Actions
GSA CAPITAL PARTNERS LLP $932 25 113 0,00% Actions
Parkside Financial Bank & Trust $817 22 0,00% Actions
Parallel Advisors, LLC $742 20 0,00% Actions
FEDERATED HERMES, INC. $705 19 0,00% Actions
Handelsbanken Fonder AB $654 19 323 0,00% Actions
CANADA LIFE ASSURANCE Co $634 17 121 0,00% Actions
Manchester Capital Management LLC $594 16 0,00% Actions
Global Retirement Partners, LLC $408 11 0,00% Actions
Steward Partners Investment Advisory, LLC $334 9 0,00% Actions
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO $252 6 796 0,00% Actions
FIDUCIARY FINANCIAL ADVISORS $185 5 0,00% Actions
State of Alaska, Department of Revenue $185 5 000 0,00% Actions
KBC Group NV $77 2 073 0,00% Actions
Fortitude Family Office, LLC $74 2 0,00% Actions
Bay Harbor Wealth Management, LLC $74 2 0,00% Actions
JFS WEALTH ADVISORS, LLC $68 2 0,00% Actions
Dunhill Financial, LLC $67 1 0,00% Actions
Rialto Wealth Management, LLC $38 1 0,00% Actions
Hughes Financial Services, LLC $37 1 0,00% Actions
Pacer Advisors, Inc. $34 928 0,00% Actions
ACADIAN ASSET MANAGEMENT LLC $31 876 0,00% Actions
BESSEMER GROUP INC $3 76 0,00% Actions
Covestor Ltd $0 12 0,00% Actions
Hemington Wealth Management $0 15 0,00% Actions