CGEM — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| MPM BIOIMPACT LLC | $177 207 720 | 9 731 341 | 13,90% | Actions |
| Lynx1 Capital Management LP | $163 225 335 | 8 963 500 | 12,81% | Actions |
| BVF INC/IL | $104 719 937 | 5 750 683 | 8,22% | Actions |
| BlackRock, Inc. | $95 288 670 | 5 232 766 | 7,48% | Actions |
| STATE STREET CORP | $66 805 698 | 3 668 627 | 5,24% | Actions |
| Kynam Capital Management, LP | $56 708 344 | 3 114 132 | 4,45% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $47 602 142 | 2 614 066 | 3,73% | Actions |
| RTW INVESTMENTS, LP | $43 054 759 | 2 364 347 | 3,38% | Actions |
| Siren, L.L.C. | $34 478 996 | 1 893 410 | 2,71% | Actions |
| VANGUARD GROUP INC | $34 139 516 | 3 298 504 | 2,68% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $28 182 326 | 1 547 309 | 2,21% | Actions |
| Blue Owl Capital Holdings LP | $28 039 102 | 1 539 764 | 2,20% | Actions |
| Venrock Adviser, LLC | $25 129 163 | 1 379 965 | 1,97% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $19 714 346 | 1 082 611 | 1,55% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $19 061 499 | 1 046 694 | 1,50% | Actions |
| GOLDMAN SACHS GROUP INC | $18 239 100 | 1 001 598 | 1,43% | Actions |
| Affinity Asset Advisors, LLC | $15 947 590 | 875 760 | 1,25% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $13 452 474 | 738 741 | 1,06% | Actions |
| BOONE CAPITAL MANAGEMENT LLC | $12 827 889 | 704 442 | 1,01% | Actions |
| Elmind Capital, LP | $12 564 900 | 690 000 | 0,99% | Actions |
| MORGAN STANLEY | $11 454 726 | 629 035 | 0,90% | Actions |
| TWIN FOCUS CAPITAL PARTNERS, LLC | $10 843 855 | 595 489 | 0,85% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $10 586 165 | 581 338 | 0,83% | Actions |
| NORTHERN TRUST CORP | $10 399 367 | 571 080 | 0,82% | Actions |
| BANK OF AMERICA CORP /DE/ | $9 293 018 | 510 325 | 0,73% | Actions |
| Nuveen, LLC | $8 594 154 | 471 947 | 0,67% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $8 450 059 | 464 034 | 0,66% | Actions |
| PERCEPTIVE ADVISORS LLC | $7 766 164 | 426 478 | 0,61% | Actions |
| TCG Crossover Management, LLC | $7 407 573 | 406 786 | 0,58% | Actions |
| CITADEL ADVISORS LLC | $7 238 184 | 397 484 | 0,57% | Actions |
| DEUTSCHE BANK AG\ | $6 971 516 | 382 840 | 0,55% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $6 612 707 | 363 136 | 0,52% | Actions |
| MILLENNIUM MANAGEMENT LLC | $6 304 885 | 346 232 | 0,49% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $5 951 228 | 326 811 | 0,47% | Actions |
| GREAT POINT PARTNERS LLC | $5 463 000 | 300 000 | 0,43% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $5 326 425 | 292 500 | 0,42% | Actions |
| JPMORGAN CHASE & CO | $5 206 063 | 282 631 | 0,41% | Actions |
| TWO SIGMA INVESTMENTS, LP | $4 963 700 | 272 581 | 0,39% | Actions |
| Bleichroeder LP | $4 552 500 | 250 000 | 0,36% | Actions |
| UBS Group AG | $4 527 498 | 248 627 | 0,36% | Actions |
| FMR LLC | $4 372 486 | 240 115 | 0,34% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $4 333 980 | 238 000 | 0,34% | Actions |
| Susquehanna Portfolio Strategies, LLC | $4 258 263 | 233 842 | 0,33% | Actions |
| PFM Health Sciences, LP | $3 504 369 | 192 442 | 0,27% | Actions |
| MOORE CAPITAL MANAGEMENT, LP | $3 458 917 | 189 946 | 0,27% | Actions |
| Bank of New York Mellon Corp | $3 114 469 | 171 031 | 0,24% | Actions |
| Squarepoint Ops LLC | $3 061 411 | 168 117 | 0,24% | Actions |
| PRUDENTIAL FINANCIAL INC | $3 051 177 | 167 555 | 0,24% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $2 999 478 | 164 716 | 0,24% | Actions |
| AMERICAN CENTURY COMPANIES INC | $2 846 533 | 156 317 | 0,22% | Actions |
| Engineers Gate Manager LP | $2 787 041 | 153 050 | 0,22% | Actions |
| Trexquant Investment LP | $2 770 888 | 152 163 | 0,22% | Actions |
| BARCLAYS PLC | $2 621 239 | 143 945 | 0,21% | Actions |
| Invesco Ltd. | $2 614 082 | 143 552 | 0,21% | Actions |
| Jump Financial, LLC | $2 525 873 | 138 708 | 0,20% | Actions |
| CITIGROUP INC | $2 265 488 | 124 409 | 0,18% | Actions |
| Quantinno Capital Management LP | $2 000 842 | 109 876 | 0,16% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 576 986 | 86 600 | 0,12% | Option d'achat |
| Creative Planning | $1 574 400 | 86 458 | 0,12% | Actions |
| Y-Intercept (Hong Kong) Ltd | $1 468 600 | 80 648 | 0,12% | Actions |
| TD Asset Management Inc | $1 468 236 | 80 628 | 0,12% | Actions |
| Apis Capital Advisors, LLC | $1 456 800 | 80 000 | 0,11% | Actions |
| RHUMBLINE ADVISERS | $1 437 306 | 78 930 | 0,11% | Actions |
| XTX Topco Ltd | $1 401 533 | 76 965 | 0,11% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1 396 907 | 76 711 | 0,11% | Actions |
| Swiss National Bank | $1 383 960 | 76 000 | 0,11% | Actions |
| Point72 Asset Management, L.P. | $1 365 914 | 75 009 | 0,11% | Actions |
| Mariner, LLC | $1 352 532 | 74 273 | 0,11% | Actions |
| TWO SIGMA ADVISERS, LP | $1 343 523 | 129 809 | 0,11% | Actions |
| Cubist Systematic Strategies, LLC | $1 318 345 | 222 318 | 0,10% | Actions |
| Knott David M Jr | $1 259 804 | 69 182 | 0,10% | Actions |
| Rafferty Asset Management, LLC | $1 203 535 | 66 092 | 0,09% | Actions |
| MARSHALL WACE, LLP | $1 202 789 | 66 051 | 0,09% | Actions |
| CITADEL ADVISORS LLC | $1 187 292 | 65 200 | 0,09% | Option de vente |
| Longaeva Partners L.P. | $1 179 735 | 64 785 | 0,09% | Actions |
| MARTINGALE ASSET MANAGEMENT L P | $1 127 891 | 61 938 | 0,09% | Actions |
| Assenagon Asset Management S.A. | $1 123 229 | 61 682 | 0,09% | Actions |
| ALLIANCEBERNSTEIN L.P. | $1 069 303 | 75 250 | 0,08% | Actions |
| Corient Private Wealth LP | $999 312 | 54 877 | 0,08% | Actions |
| KENNEDY CAPITAL MANAGEMENT LLC | $965 312 | 53 010 | 0,08% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $961 392 | 67 656 | 0,08% | Actions |
| WELLS FARGO & COMPANY/MN | $933 372 | 51 256 | 0,07% | Actions |
| CITADEL ADVISORS LLC | $919 605 | 50 500 | 0,07% | Option d'achat |
| Soleus Capital Management, L.P. | $910 500 | 50 000 | 0,07% | Actions |
| FRANKLIN RESOURCES INC | $771 103 | 42 345 | 0,06% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $733 007 | 40 253 | 0,06% | Actions |
| ALGERT GLOBAL LLC | $671 057 | 36 851 | 0,05% | Actions |
| Vanguard Global Advisers, LLC | $669 709 | 36 777 | 0,05% | Actions |
| JANE STREET GROUP, LLC | $668 307 | 36 700 | 0,05% | Option de vente |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $655 560 | 36 000 | 0,05% | Option de vente |
| Fisher Asset Management, LLC | $655 523 | 35 998 | 0,05% | Actions |
| MetLife Investment Management, LLC | $650 935 | 35 746 | 0,05% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $648 704 | 35 535 | 0,05% | Actions |
| IEQ CAPITAL, LLC | $614 041 | 33 720 | 0,05% | Actions |
| PROFUND ADVISORS LLC | $608 269 | 33 403 | 0,05% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $585 215 | 32 137 | 0,05% | Actions |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $577 494 | 31 713 | 0,05% | Actions |
| Leonteq Securities AG | $546 300 | 30 000 | 0,04% | Actions |
| Verdad Advisers, LP | $527 853 | 28 987 | 0,04% | Actions |
| Russell Investments Group, Ltd. | $520 514 | 28 584 | 0,04% | Actions |
| ExodusPoint Capital Management, LP | $519 659 | 28 537 | 0,04% | Actions |
| OPTIMIZE FINANCIAL INC. | $510 991 | 28 061 | 0,04% | Actions |
| JANE STREET GROUP, LLC | $508 059 | 27 900 | 0,04% | Option d'achat |
| Legal & General Group Plc | $500 356 | 27 477 | 0,04% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $475 099 | 26 090 | 0,04% | Actions |
| PANAGORA ASSET MANAGEMENT INC | $444 251 | 24 396 | 0,03% | Actions |
| Virtus Investment Advisers, LLC | $434 909 | 23 883 | 0,03% | Actions |
| TUDOR INVESTMENT CORP ET AL | $410 053 | 22 518 | 0,03% | Actions |
| MERCER GLOBAL ADVISORS INC /ADV | $399 200 | 21 922 | 0,03% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $386 380 | 21 218 | 0,03% | Actions |
| TEMA ETFS LLC | $382 577 | 36 964 | 0,03% | Actions |
| AlphaCentric Advisors LLC | $371 957 | 20 426 | 0,03% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $370 537 | 20 348 | 0,03% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $365 111 | 20 050 | 0,03% | Actions |
| Birchview Capital, LP | $364 200 | 20 000 | 0,03% | Actions |
| MILLENNIUM MANAGEMENT LLC | $364 200 | 20 000 | 0,03% | Option d'achat |
| Qube Research & Technologies Ltd | $363 035 | 19 936 | 0,03% | Actions |
| Police & Firemen's Retirement System of New Jersey | $324 885 | 17 841 | 0,03% | Actions |
| SIMPLEX TRADING, LLC | $317 655 | 17 444 | 0,02% | Actions |
| AlphaQuest LLC | $299 633 | 28 950 | 0,02% | Actions |
| TWO SIGMA SECURITIES, LLC | $277 156 | 15 220 | 0,02% | Actions |
| AXQ CAPITAL, LP | $271 966 | 14 935 | 0,02% | Actions |
| JANUS HENDERSON GROUP PLC | $263 190 | 18 528 | 0,02% | Actions |
| SEI INVESTMENTS CO | $244 852 | 13 446 | 0,02% | Actions |
| Nebula Research & Development LLC | $239 853 | 31 853 | 0,02% | Actions |
| INTECH INVESTMENT MANAGEMENT LLC | $226 132 | 12 418 | 0,02% | Actions |
| Pale Fire Capital SE | $226 132 | 12 418 | 0,02% | Actions |
| State of New Jersey Common Pension Fund D | $222 745 | 12 232 | 0,02% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $215 151 | 11 815 | 0,02% | Actions |
| GREAT LAKES ADVISORS, LLC | $214 987 | 11 806 | 0,02% | Actions |
| Inscription Capital, LLC | $212 347 | 11 661 | 0,02% | Actions |
| EntryPoint Capital, LLC | $210 435 | 11 556 | 0,02% | Actions |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $202 475 | 11 168 | 0,02% | Actions |
| Campbell & CO Investment Adviser LLC | $201 949 | 11 090 | 0,02% | Actions |
| GROUP ONE TRADING LLC | $195 994 | 10 763 | 0,02% | Actions |
| ARIZONA STATE RETIREMENT SYSTEM | $190 076 | 10 438 | 0,01% | Actions |
| China Universal Asset Management Co., Ltd. | $178 112 | 9 781 | 0,01% | Actions |
| Quarry LP | $176 127 | 9 672 | 0,01% | Actions |
| CWM, LLC | $173 305 | 12 196 | 0,01% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $172 776 | 9 488 | 0,01% | Actions |
| Corton Capital Inc. | $160 804 | 27 117 | 0,01% | Actions |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $139 143 | 7 641 | 0,01% | Actions |
| Vanguard Investments Australia, Ltd. | $132 423 | 7 272 | 0,01% | Actions |
| KLP KAPITALFORVALTNING AS | $123 828 | 6 800 | 0,01% | Actions |
| ROYAL BANK OF CANADA | $106 000 | 5 820 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $99 973 | 5 490 | 0,01% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $69 672 | 3 825 950 | 0,01% | Actions |
| SIGNATUREFD, LLC | $58 399 | 3 207 | 0,00% | Actions |
| Tower Research Capital LLC (TRC) | $58 108 | 3 191 | 0,00% | Actions |
| Quantbot Technologies LP | $53 009 | 2 911 | 0,00% | Actions |
| Allworth Financial LP | $52 682 | 2 893 | 0,00% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $50 059 | 2 749 | 0,00% | Actions |
| Arax Advisory Partners | $47 802 | 2 625 | 0,00% | Actions |
| GAMMA Investing LLC | $35 109 | 1 928 | 0,00% | Actions |
| Parallel Advisors, LLC | $34 107 | 1 873 | 0,00% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $26 259 | 1 442 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $25 312 | 1 390 | 0,00% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $22 799 | 1 252 | 0,00% | Actions |
| Sterling Capital Management LLC | $22 198 | 1 219 | 0,00% | Actions |
| Point72 (DIFC) Ltd | $21 070 | 3 553 | 0,00% | Actions |
| STRS OHIO | $18 210 | 1 000 | 0,00% | Actions |
| Farther Finance Advisors, LLC | $15 488 | 849 | 0,00% | Actions |
| Bangor Savings Bank | $15 333 | 842 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $14 441 | 793 | 0,00% | Actions |
| IFP Advisors, Inc | $13 257 | 728 | 0,00% | Actions |
| UMB Bank, n.a. | $12 474 | 685 | 0,00% | Actions |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $12 437 | 683 | 0,00% | Actions |
| Rockefeller Capital Management L.P. | $11 818 | 649 | 0,00% | Actions |
| US BANCORP \DE\ | $9 415 | 517 | 0,00% | Actions |
| Essential Partners LLC | $9 287 | 510 | 0,00% | Actions |
| FEDERATED HERMES, INC. | $7 065 | 388 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $5 736 | 315 | 0,00% | Actions |
| Larson Financial Group LLC | $5 081 | 279 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $4 607 | 253 | 0,00% | Actions |
| Federation des caisses Desjardins du Quebec | $4 553 | 250 | 0,00% | Actions |
| Fortitude Family Office, LLC | $3 496 | 192 | 0,00% | Actions |
| Optiver Holding B.V. | $2 549 | 140 | 0,00% | Actions |
| SJS Investment Consulting Inc. | $2 204 | 121 | 0,00% | Actions |
| Wealth Enhancement Trust Services, Inc. | $1 439 | 79 | 0,00% | Actions |
| Silver Grove Financial Group, Inc. | $1 293 | 71 | 0,00% | Actions |
| True Wealth Design, LLC | $1 293 | 71 | 0,00% | Actions |
| Lindbrook Capital, LLC | $1 196 | 158 | 0,00% | Actions |
| COMERICA BANK | $683 | 66 | 0,00% | Actions |
| MassMutual Private Wealth & Trust, FSB | $492 | 27 | 0,00% | Actions |
| Smartleaf Asset Management LLC | $479 | 26 | 0,00% | Actions |
| NATIONAL BANK OF CANADA /FI/ | $419 | 23 | 0,00% | Actions |
| ACADIAN ASSET MANAGEMENT LLC | $366 | 20 279 | 0,00% | Actions |
| SG Americas Securities, LLC | $347 | 19 058 | 0,00% | Actions |
| Clearstead Advisors, LLC | $275 | 15 | 0,00% | Actions |
| PNC Financial Services Group, Inc. | $273 | 15 | 0,00% | Actions |
| FIFTH THIRD BANCORP | $55 | 3 | 0,00% | Actions |
| Capital Advisors, Ltd. LLC | $29 | 1 600 | 0,00% | Actions |
| Pacer Advisors, Inc. | $20 | 1 104 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $18 | 1 | 0,00% | Actions |
| Avion Wealth | $3 | 200 | 0,00% | Actions |
| Covestor Ltd | $1 | 33 | 0,00% | Actions |