KPTI — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $18 732 549 | 1 917 354 | 8,69% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $14 863 316 | 1 521 322 | 6,89% | Actions |
| ACORN CAPITAL ADVISORS, LLC | $14 831 964 | 1 518 113 | 6,88% | Actions |
| GOLDMAN SACHS GROUP INC | $13 918 908 | 1 424 658 | 6,46% | Actions |
| BlackRock, Inc. | $13 861 666 | 1 418 799 | 6,43% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $9 369 225 | 958 979 | 4,35% | Actions |
| Catalio Capital Management, LP | $9 192 153 | 940 855 | 4,26% | Actions |
| Avidity Partners Management LP | $9 032 238 | 924 487 | 4,19% | Actions |
| TWO SIGMA INVESTMENTS, LP | $6 792 729 | 695 264 | 3,15% | Actions |
| Kalehua Capital Management LLC | $6 698 742 | 685 644 | 3,11% | Actions |
| NEA Management Company, LLC | $5 635 141 | 576 780 | 2,61% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $5 191 417 | 531 231 | 2,41% | Actions |
| Ghisallo Capital Management LLC | $4 885 000 | 500 000 | 2,27% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4 736 496 | 484 800 | 2,20% | Option d'achat |
| Soleus Capital Management, L.P. | $4 298 800 | 440 000 | 1,99% | Actions |
| VANGUARD GROUP INC | $4 118 796 | 559 619 | 1,91% | Actions |
| UBS Group AG | $3 454 135 | 353 545 | 1,60% | Actions |
| STATE STREET CORP | $3 184 932 | 325 991 | 1,48% | Actions |
| Affinity Asset Advisors, LLC | $3 053 125 | 312 500 | 1,42% | Actions |
| Brevan Howard Capital Management LP | $3 026 912 | 309 817 | 1,40% | Actions |
| MILLENNIUM MANAGEMENT LLC | $2 986 455 | 305 676 | 1,39% | Actions |
| Boxer Capital Management, LLC | $2 955 777 | 302 536 | 1,37% | Actions |
| Davidson Kempner Capital Management LP | $2 931 000 | 300 000 | 1,36% | Actions |
| SILVERARC CAPITAL MANAGEMENT, LLC | $2 906 184 | 297 460 | 1,35% | Actions |
| Caption Management, LLC | $2 791 289 | 285 700 | 1,29% | Option d'achat |
| Eversept Partners, LP | $2 698 220 | 276 174 | 1,25% | Actions |
| Tetragon Partners GP Ltd | $2 445 431 | 250 300 | 1,13% | Option d'achat |
| JPMORGAN CHASE & CO | $2 093 737 | 207 609 | 0,97% | Actions |
| MORGAN STANLEY | $1 978 485 | 202 506 | 0,92% | Actions |
| Trexquant Investment LP | $1 840 355 | 188 368 | 0,85% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $1 837 131 | 188 038 | 0,85% | Actions |
| BARCLAYS PLC | $1 620 882 | 165 904 | 0,75% | Actions |
| NORTHERN TRUST CORP | $1 563 258 | 160 006 | 0,73% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $1 420 568 | 145 401 | 0,66% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1 317 172 | 134 818 | 0,61% | Actions |
| MARSHALL WACE, LLP | $1 254 967 | 128 451 | 0,58% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $1 057 251 | 108 214 | 0,49% | Actions |
| DLD Asset Management, LP | $989 625 | 101 500 | 0,46% | Option de vente |
| SILVERBACK ASSET MANAGEMENT LLC | $977 000 | 100 000 | 0,45% | Option d'achat |
| Jump Financial, LLC | $918 380 | 94 000 | 0,43% | Actions |
| Caption Management, LLC | $903 725 | 92 500 | 0,42% | Option de vente |
| Invesco Ltd. | $882 270 | 90 304 | 0,41% | Actions |
| DLD Asset Management, LP | $780 975 | 80 100 | 0,36% | Option d'achat |
| Connor, Clark & Lunn Investment Management Ltd. | $746 399 | 76 397 | 0,35% | Actions |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $702 199 | 71 873 | 0,33% | Actions |
| J. Goldman & Co LP | $660 452 | 67 600 | 0,31% | Option de vente |
| TWO SIGMA ADVISERS, LP | $660 405 | 89 729 | 0,31% | Actions |
| J. Goldman & Co LP | $659 475 | 67 500 | 0,31% | Actions |
| Squarepoint Ops LLC | $623 336 | 63 801 | 0,29% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $605 183 | 61 943 | 0,28% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $594 993 | 60 900 | 0,28% | Option de vente |
| ROYAL BANK OF CANADA | $590 000 | 60 430 | 0,27% | Actions |
| Bank of New York Mellon Corp | $559 446 | 57 262 | 0,26% | Actions |
| Susquehanna Portfolio Strategies, LLC | $532 905 | 54 545 | 0,25% | Actions |
| XTX Topco Ltd | $520 467 | 53 272 | 0,24% | Actions |
| CITADEL ADVISORS LLC | $509 994 | 52 200 | 0,24% | Option d'achat |
| CITADEL ADVISORS LLC | $508 714 | 52 069 | 0,24% | Actions |
| BANK OF AMERICA CORP /DE/ | $487 758 | 49 924 | 0,23% | Actions |
| CITIGROUP INC | $370 449 | 37 917 | 0,17% | Actions |
| Nuveen, LLC | $369 971 | 37 868 | 0,17% | Actions |
| MILLENNIUM MANAGEMENT LLC | $351 720 | 36 000 | 0,16% | Option de vente |
| Engineers Gate Manager LP | $331 848 | 33 966 | 0,15% | Actions |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $326 000 | 33 333 | 0,15% | Actions |
| JANE STREET GROUP, LLC | $324 100 | 33 173 | 0,15% | Actions |
| TORONTO DOMINION BANK | $302 186 | 30 930 | 0,14% | Actions |
| SILVERBACK ASSET MANAGEMENT LLC | $293 100 | 30 000 | 0,14% | Actions |
| Baird Financial Group, Inc. | $291 058 | 29 791 | 0,14% | Actions |
| JANE STREET GROUP, LLC | $286 261 | 29 300 | 0,13% | Option d'achat |
| ExodusPoint Capital Management, LP | $259 706 | 26 582 | 0,12% | Actions |
| China Universal Asset Management Co., Ltd. | $244 250 | 25 000 | 0,11% | Actions |
| SIMPLEX TRADING, LLC | $235 320 | 24 086 | 0,11% | Actions |
| JANE STREET GROUP, LLC | $232 526 | 23 800 | 0,11% | Option de vente |
| RHUMBLINE ADVISERS | $229 266 | 23 467 | 0,11% | Actions |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | $227 299 | 23 265 | 0,11% | Actions |
| Velan Capital Investment Management LP | $195 400 | 20 000 | 0,09% | Actions |
| DEUTSCHE BANK AG\ | $189 782 | 19 425 | 0,09% | Actions |
| WELLS FARGO & COMPANY/MN | $165 142 | 16 903 | 0,08% | Actions |
| SEI INVESTMENTS CO | $147 361 | 15 083 | 0,07% | Actions |
| HSBC HOLDINGS PLC | $137 363 | 13 750 | 0,06% | Actions |
| CITADEL ADVISORS LLC | $133 849 | 13 700 | 0,06% | Option de vente |
| Headlands Technologies LLC | $118 344 | 12 113 | 0,05% | Actions |
| MetLife Investment Management, LLC | $117 406 | 12 017 | 0,05% | Actions |
| Y-Intercept (Hong Kong) Ltd | $101 364 | 10 375 | 0,05% | Actions |
| Quadrature Capital Ltd | $100 592 | 10 296 | 0,05% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $89 601 | 9 171 | 0,04% | Actions |
| FMR LLC | $87 305 | 8 936 | 0,04% | Actions |
| Vanguard Global Advisers, LLC | $80 182 | 8 207 | 0,04% | Actions |
| Police & Firemen's Retirement System of New Jersey | $57 389 | 5 874 | 0,03% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $54 712 | 5 600 | 0,03% | Actions |
| TD Waterhouse Canada Inc. | $54 502 | 5 707 | 0,03% | Actions |
| Legal & General Group Plc | $18 905 | 1 935 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $17 664 | 1 808 | 0,01% | Actions |
| Russell Investments Group, Ltd. | $15 553 | 1 592 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $12 300 | 1 259 | 0,01% | Actions |
| T. Rowe Price Investment Management, Inc. | $7 683 | 786 309 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $3 927 | 402 | 0,00% | Actions |
| Sterling Capital Management LLC | $3 439 | 352 | 0,00% | Actions |
| ACADIAN ASSET MANAGEMENT LLC | $2 916 | 298 997 | 0,00% | Actions |
| HARBOUR INVESTMENTS, INC. | $2 784 | 285 | 0,00% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2 677 | 274 | 0,00% | Actions |
| Quent Capital, LLC | $1 622 | 166 | 0,00% | Actions |
| MB, LEVIS & ASSOCIATES, LLC | $977 | 100 | 0,00% | Actions |
| C WorldWide Group Holding A/S | $977 | 100 000 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $655 | 67 | 0,00% | Actions |
| Activest Wealth Management | $645 | 66 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $266 | 27 225 | 0,00% | Actions |
| Allworth Financial LP | $255 | 26 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $137 | 14 | 0,00% | Actions |
| Virtu Financial LLC | $105 | 10 728 | 0,00% | Actions |
| CIBC Private Wealth Group LLC | $20 | 3 | 0,00% | Actions |
| West Branch Capital LLC | $17 | 3 | 0,00% | Actions |
| PlanVest Financial, Inc | $10 | 1 | 0,00% | Actions |